Cancer Database Query Results

Scientific Papers found: Click to Expand⟱

4404-

AgNPs,

Rad,

Main Approaches to Enhance Radiosensitization in Cancer Cells by Nanoparticles: A Systematic Review

Review,

Var,

eff↑, ROS↑,

4402-

AgNPs,

Enhancement of Triple-Negative Breast Cancer-Specific Induction of Cell Death by Silver Nanoparticles by Combined Treatment with Proteotoxic Stress Response Inhibitors

in-vitro,

BC,

BT549

in-vitro,

BC,

MDA-MB-231

in-vitro,

Nor,

MCF10

TumCD↑, selectivity↑, *toxicity↝, Dose↝, OS↑,

4401-

AgNPs,

Rad,

Metformin-loaded chitosan nanoparticles augment silver nanoparticle-induced radiosensitization in breast cancer cells during radiation therapy

in-vitro,

BC,

 Met NPs and AgNPs had average diameters of 51.5 ± 9.4 nm and 3.02 ± 0.03 nm,

RadioS↑, DNAdam↑,

4400-

AgNPs,

Rad,

Differential cytotoxic and radiosensitizing effects of silver nanoparticles on triple-negative breast cancer and non-triple-negative breast cells

in-vitro,

BC,

MCF-7

in-vitro,

Nor,

MCF10

in-vitro,

BC,

MDA-MB-231

in-vitro,

BC,

BT549

in-vivo,

BC,

MDA-MB-231

right hind flanks of the mice

ROS↑, DNAdam↑, selectivity↑, TumCG↓, RadioS↑, Dose↝, selectivity↑, other↝, eff↓, eff↑, γH2AX↑, Dose↓, eff↑,

4399-

AgNPs,

Chit,

Silver nanoparticles impregnated alginate-chitosan-blended nanocarrier induces apoptosis in human glioblastoma cells

in-vitro,

GBM,

U87MG

 2.4 μg mL(-1) for Ag NPs

DNAdam↑, ROS↑, MMP↓, eff↑,

4398-

AgNPs,

Induction of apoptosis in cancer cells at low silver nanoparticle concentrations using chitosan nanocarrier

in-vitro,

Colon,

HT29

0.33 μg mL(-1)

Apoptosis↑, MMP↓, Casp3↑, ROS↑, eff↑,

4397-

AgNPs,

Synthesis and Characterization of Silver Nanoparticles from Rhizophora apiculata and Studies on Their Wound Healing, Antioxidant, Anti-Inflammatory, and Cytotoxic Activity

NA,

Wounds,

 99 nm, with a zeta potential of −6 mV

selectivity↑, tumCV↓, antiOx↑, Inflam↓,

4396-

AgNPs,

Identification of possible reductants in the aqueous leaf extract of mangrove plant Rhizophora apiculata for the fabrication and cytotoxicity of silver nanoparticles against human osteosarcoma MG-63 cells

in-vitro,

OS,

MG63

AntiCan↑, tumCV↓,

4395-

AgNPs,

Hepatoprotective effect of silver nanoparticles synthesized using aqueous leaf extract of Rhizophora apiculata

in-vivo,

LiverDam,

hepatotoxin-induced liver damage in experimental mice

*hepatoP↑, *LDH↓,

4394-

AgNPs,

Silver nanoparticles provoke apoptosis of Dalton's ascites lymphoma in vivo by mitochondria dependent and independent pathways

in-vivo,

lymphoma,

OS↑, TumVol↓, Weight↑, AntiTum↑, Apoptosis↑, mtDam↑,

4393-

AgNPs,

Nanotoxic Effects of Silver Nanoparticles on Normal HEK-293 Cells in Comparison to Cancerous HeLa Cell Line

in-vitro,

Cerv,

HeLa

1.98 µL/mL

in-vitro,

Nor,

HEK293

0.622 µL/mL

selectivity↓,

4392-

AgNPs,

Hepatocurative activity of biosynthesized silver nanoparticles fabricated using Andrographis paniculata

in-vivo,

LiverDam,

13-27 nm. Zeta potential was -34.3 mV indicating stable AgNPs.

 CCl(4) induced liver injury.

*antiOx↑, *eff?,

4391-

AgNPs,

Silver Nanoparticles Induce Apoptosis in HepG2 Cells through Particle-Specific Effects on Mitochondria

NA,

Liver,

HepG2

Apoptosis↑,

4390-

AgNPs,

Therapeutic Potential of Cucumis melo (L.) Fruit Extract and Its Silver Nanopartciles Against DEN-Induced Hepatocellular Cancer in Rats

in-vivo,

Liver,

 Wistar rats were divided into six groups and hepatic cancer was induced with 0.01% DEN (diethylnitrosamine) through drinking water for 16 weeks.

hepatoP↑, AST↓, ALAT↓, ALP↓,

4389-

AgNPs,

Graphene Oxide-Silver Nanocomposite Enhances Cytotoxic and Apoptotic Potential of Salinomycin in Human Ovarian Cancer Stem Cells (OvCSCs): A Novel Approach for Cancer Therapy

in-vitro,

Ovarian,

tumCV↓, ROS↑, LDH↓, MMP↑, CSCs↓, AntiCan↑,

4388-

AgNPs,

Differential Cytotoxic Potential of Silver Nanoparticles in Human Ovarian Cancer Cells and Ovarian Cancer Stem Cells

in-vitro,

Cerv,

47.5 nm

tumCV↓, CSCs↓, selectivity↑, Apoptosis↑, ROS↑, LDH↓, Casp3↑, BAX↑, Bak↑, cMyc↑, MMP↓,

4387-

AgNPs,

Attenuation of diethylnitrosamine (DEN) - Induced hepatic cancer in experimental model of Wistar rats by Carissa carandas embedded silver nanoparticles

in-vitro,

Liver,

IL6↓, TNF-α↓, IL1β↓, hepatoP↑,

4386-

AgNPs,

Evaluation of hepatic cancer stem cells (CD73+, CD44+, and CD90+) induced by diethylnitrosamine in male rats and treatment with biologically synthesized silver nanoparticles

hepatoP↑, CD44↓, CSCs↓,

4385-

AgNPs,

Hepatoprotective effect of engineered silver nanoparticles coated bioactive compounds against diethylnitrosamine induced hepatocarcinogenesis in experimental mice

in-vitro,

Liver,

hepatoP↑, *AST↓, *ALAT↓, *Catalase↑, *GPx↑, *GSTA1↑, *SOD↑,

4414-

AgNPs,

Silver nanoparticles: Forging a new frontline in lung cancer therapy

Review,

Lung,

tumCV↑, ROS↑, MMP↓, TumCCA↑, Apoptosis↑, angioG↓,

4423-

AgNPs,

Pongamia pinnata seed extract-mediated green synthesis of silver nanoparticle loaded nanogel for estimation of their antipsoriatic properties

in-vivo,

PSA,

 116 nm

*eff↑, *other↑,

4422-

AgNPs,

Bioengineering of Piper longum L. extract mediated silver nanoparticles and their potential biomedical applications

in-vitro,

Cerv,

HeLa

AntiCan↑, selectivity↑,

4421-

AgNPs,

Effect of Biologically Synthesized Silver Nanoparticles on Human Cancer Cells

in-vitro,

Cerv,

selectivity↑, eff↝, other↝,

4424-

AgNPs,

Understanding the prospective of nano-formulations towards the treatment of psoriasis

in-vivo,

PSA,

*eff↑,

4419-

AgNPs,

Tackling the various classes of nano-therapeutics employed in topical therapy of psoriasis

NA,

PSA,

IL1α↓, other↝,

4418-

AgNPs,

Nanocarriers for the topical treatment of psoriasis - pathophysiology, conventional treatments, nanotechnology, regulatory and toxicology

Human,

PSA,

*Inflam↓, *EPR↑,

4417-

AgNPs,

Caffeine-boosted silver nanoparticles target breast cancer cells by triggering oxidative stress, inflammation, and apoptotic pathways

in-vitro,

BC,

MDA-MB-231

ROS↑, MDA↑, COX2↑, IL1β↑, TNF-α↑, GSH↓, Cyt‑c↑, Casp3↑, BAX↑, Bcl-2↓, LDH↓, cycD1/CCND1↓, CDK2↓, TumCCA↑, mt-Apoptosis↑,

4416-

AgNPs,

Efficacy of curcumin-synthesized silver nanoparticles on MCF-7 breast cancer cells

in-vitro,

BC,

MCF-7

TumCMig↓, Apoptosis↑, BAX↑, P53↑, Bcl-2↓,

4415-

AgNPs,

SDT,

CUR,

Examining the Impact of Sonodynamic Therapy With Ultrasound Wave in the Presence of Curcumin-Coated Silver Nanoparticles on the Apoptosis of MCF7 Breast Cancer Cells

in-vitro,

BC,

MCF-7

29.3 ± 5.6 nm

 48.23 µg/ml

SDT was performed using an US frequency of 1 MHz, intensity of 2 W/cm2, and a distance of 2 cm.

tumCV↓, BAX↑, Casp3↑, Bcl-2↓, eff↑, ROS↑, sonoS↑, eff↑, MMP↓, Cyt‑c↑,

4382-

AgNPs,

Silver nanoparticles induce cytotoxicity by a Trojan-horse type mechanism

in-vitro,

Nor,

RAW264.7

68.9 nm, concentrations; 0.2, 0.4, 0.8, and 1.6 ppm, exposure time; 24, 48, 72, and 96 h

*GSH↓, *NO↑, *TNF-α↑, *MMP3↑, *MMP11↑,

4413-

AgNPs,

Anzaroot,

Green synthesis of silver nanoparticles from plant Astragalus fasciculifolius Bioss and evaluating cytotoxic effects on MCF7 human breast cancer cells

in-vitro,

BC,

MCF-7

12.35 μg/mL

The IC50 value for root extract-mediated SNPs was found to be 21.73 μg/mL

chemoP↑, TumCG↓, eff↑, CellMemb↑, selectivity↑, ROS↑, P53↑,

4412-

AgNPs,

Biosynthesis and characterization of silver nanoparticles from Asplenium dalhousiae and their potential biological properties

in-vitro,

CRC,

HCT116

in-vitro,

Melanoma,

A2780S

Bacteria↓, antiOx↑, AntiCan↑, eff↑,

4411-

AgNPs,

Eco-friendly synthesis of silver nanoparticles using Anemone coronaria bulb extract and their potent anticancer and antibacterial activities

in-vitro,

Lung,

A549

in-vitro,

PC,

MIA PaCa-2

in-vitro,

Pca,

PC3

in-vitro,

Nor,

HEK293

AntiCan↑, selectivity↑, Apoptosis↑, TumCCA↑, Bacteria↓, tumCV↓, selectivity↑, Apoptosis↑, TumCCA↑,

4410-

AgNPs,

Green-synthesized silver nanoparticles: a sustainable nanoplatform for targeted colon cancer therapy

Review,

Colon,

AntiCan↑, ROS↑, mtDam↑, tumCV↓, selectivity↑,

4409-

AgNPs,

Plant-based synthesis of gold and silver nanoparticles using Artocarpus heterophyllus aqueous leaf extract and its anticancer activities

in-vitro,

BC,

MCF-7

12.75 nm

54.981 µg/mL

tumCV↓, TumCCA↑, cycD1/CCND1↓, COX2↓, HER2/EBBR2↓,

4408-

AgNPs,

Chitosan-coated silver nanoparticles synthesized using Moringa oleifera flower extract: A potential therapeutic approach against triple-negative breast cancer

in-vitro,

BC,

MDA-MB-231

 27 ± 0.5 μg/mL

tumCV↓,

4407-

AgNPs,

Green Synthesis and Characterization of Silver Nanoparticles from Eclipta alba and Its Activity Against Triple-Negative Breast Cancer Cell Line (MDA-MB-231)

in-vitro,

BC,

MDA-MB-231

 40-60 nm

antiOx↑, TumCG↓,

4406-

AgNPs,

Silver nanoparticles achieve cytotoxicity against breast cancer by regulating long-chain noncoding RNA XLOC_006390-mediated pathway

in-vitro,

BC,

MCF-7

63.1 ± 8.3 nm

tissues from 64 patients

in-vitro,

BC,

T47D

in-vitro,

BC,

MDA-MB-231

TumCD↑, other↓, P53↑, TumCCA↑, Apoptosis↑, ChemoSen↑, tumCV↓, γH2AX↑, SOX4↓,

4405-

AgNPs,

Silver nanoparticles defeat p53-positive and p53-negative osteosarcoma cells by triggering mitochondrial stress and apoptosis

in-vitro,

OS,

Apoptosis↑, other↑, ROS↑, eff↑, P53↝, Apoptosis↑, cl‑Casp3↑, survivin↓, MMP↓, Cyt‑c↑,

4431-

AgNPs,

doxoR,

Oxidative Stress-Induced Silver Nano-Carriers for Chemotherapy

in-vitro,

BC,

4T1

PA-AgNPs have an average hydrodynamic diameter of 130 nm

in-vivo,

BC,

4T1

in-vitro,

Nor,

3T3

AntiCan↑, ROS↑, TumVol↓, EPR↑, selectivity↑, ChemoSen↑,

4362-

AgNPs,

Enhancing Colorectal Cancer Radiation Therapy Efficacy using Silver Nanoprisms Decorated with Graphene as Radiosensitizers

in-vitro,

CRC,

HCT116

18–45 nm.

in-vitro,

CRC,

HT29

in-vivo,

NA,

Male Swiss nu/nu mice aged 5–8 weeks

eff↑, TumCG↓, OS↑, RadioS↑, eff↑, ROS↑, DNAdam↑, eff↝,

4361-

AgNPs,

GoldNP,

Biocompatible silver, gold and silver/gold alloy nanoparticles for enhanced cancer therapy: in vitro and in vivo perspectives

in-vivo,

Liver,

HepG2

IC50 values of the AgNPs, AuNPs and Ag/AuNPs on HepG2 cells were determined as 38.42 μg ml-1, 43.25 μg ml-1 and 39.20 μg ml-1

Sprague Dawley (SD) rat model

TumCD↑, TumVol↓, *toxicity↝, hepatoP↑,

4360-

AgNPs,

Silver Nanoparticles as Real Topical Bullets for Wound Healing

Study,

Nor,

*other↝, *toxicity↓, *eff↑, *eff↑, *Inflam↓, *IL6↓, *TGF-β↑, *MMP9↓, *eff↑,

4359-

AgNPs,

Antimicrobial Silver Nanoparticles for Wound Healing Application: Progress and Future Trends

NA,

Wounds,

*Bacteria↓, *eff↑, *other↝, *toxicity↓,

4358-

AgNPs,

HPT,

Rad,

Silver nanocrystals mediated combination therapy of radiation with magnetic hyperthermia on glioma cells

in-vitro,

GBM,

U251

10 nm silver nanoparticles (AgNPs) on human glioma U251 c

RadioS↑, eff↑, TumCD↑,

4426-

AgNPs,

Antiangiogenic properties of silver nanoparticles

Study,

NA,

angioG↑, TumCG↓, TumCI↓, TumMeta↓, VEGF↓, PI3K↓, Akt↓,

4427-

AgNPs,

Silver nanoparticles induce apoptosis and G2/M arrest via PKCζ-dependent signaling in A549 lung cells

in-vitro,

Lung,

A549

tumCV↓, LDH↑, TumCCA↑, BAX↑, BID↑, Bcl-2↓, PKCδ↓,

4428-

AgNPs,

p38 MAPK Activation, DNA Damage, Cell Cycle Arrest and Apoptosis As Mechanisms of Toxicity of Silver Nanoparticles in Jurkat T Cells

in-vitro,

AML,

Jurkat

toxicity↝, tumCV↓, ROS↑, p38↑, NRF2↓, NF-kB↝, DNAdam↑, Apoptosis↑,

4429-

AgNPs,

Comparative proteomic analysis reveals the different hepatotoxic mechanisms of human hepatocytes exposed to silver nanoparticles

in-vitro,

Liver,

HepG2

*toxicity↝, selectivity↑, mt-ROS↑,

4430-

AgNPs,

Evaluation of the Genotoxic and Oxidative Damage Potential of Silver Nanoparticles in Human NCM460 and HCT116 Cells

in-vitro,

Colon,

HCT116

20 nm

in-vitro,

Nor,

NCM460

*Bacteria↓, ROS↑, p‑p38↑, BAX↑, Bcl-2↓, BAX↑, P21↑, TumCD↑, toxicity↝,

Showing Research Papers: 151 to 200 of 5729
Prev Page 4 of 115 Next

* indicates research on normal cells as opposed to diseased cells
Total Research Paper Matches: 5729

Pathway results for Effect on Cancer / Diseased Cells:

Infection & Microbiome ⓘ

Bacteria↓, 2,
Total Targets: 91

Pathway results for Effect on Normal Cells:

Redox & Oxidative Stress ⓘ

antiOx↑, 1, Catalase↑, 1, GPx↑, 1, GSH↓, 1, GSTA1↑, 1, SOD↑, 1,

Core Metabolism/Glycolysis ⓘ

ALAT↓, 1, LDH↓, 1,

Transcription & Epigenetics ⓘ

other↑, 1, other↝, 2,

Migration ⓘ

MMP11↑, 1, MMP3↑, 1, MMP9↓, 1, TGF-β↑, 1,

Angiogenesis & Vasculature ⓘ

EPR↑, 1, NO↑, 1,

Immune & Inflammatory Signaling ⓘ

IL6↓, 1, Inflam↓, 2, TNF-α↑, 1,

Drug Metabolism & Resistance ⓘ

eff?, 1, eff↑, 6,

Clinical Biomarkers ⓘ

ALAT↓, 1, AST↓, 1, IL6↓, 1, LDH↓, 1,

Functional Outcomes ⓘ

hepatoP↑, 1, toxicity↓, 2, toxicity↝, 3,

Infection & Microbiome ⓘ

Bacteria↓, 2,
Total Targets: 29

Query results interpretion may depend on "conditions" listed in the research papers.
Such Conditions may include : 
  -low or high Dose
  -format for product, such as nano of lipid formations
  -different cell line effects
  -synergies with other products 
  -if effect was for normal or cancerous cells

Filter Conditions: Pro/AntiFlg:%  IllCat:%  CanType:%  Cells:%  prod#:%  Target#:%  State#:%  Dir#:%
  wNotes=0  sortOrder:rid,rpid

Cancer Database Query Results

Pathway results for Effect on Cancer / Diseased Cells:

Redox & Oxidative Stress ⓘ

Mitochondria & Bioenergetics ⓘ

Core Metabolism/Glycolysis ⓘ

Cell Death ⓘ

Kinase & Signal Transduction ⓘ

Transcription & Epigenetics ⓘ

DNA Damage & Repair ⓘ

Cell Cycle & Senescence ⓘ

Proliferation, Differentiation & Cell State ⓘ

Migration ⓘ

Angiogenesis & Vasculature ⓘ

Barriers & Transport ⓘ

Immune & Inflammatory Signaling ⓘ

Drug Metabolism & Resistance ⓘ

Clinical Biomarkers ⓘ

Functional Outcomes ⓘ

Infection & Microbiome ⓘ

Pathway results for Effect on Normal Cells:

Redox & Oxidative Stress ⓘ

Core Metabolism/Glycolysis ⓘ

Transcription & Epigenetics ⓘ

Migration ⓘ

Angiogenesis & Vasculature ⓘ

Immune & Inflammatory Signaling ⓘ

Drug Metabolism & Resistance ⓘ

Clinical Biomarkers ⓘ

Functional Outcomes ⓘ

Infection & Microbiome ⓘ

Home Page