Cancer Database Query Results

Scientific Papers found: Click to Expand⟱
6867- FA,  Ang,    Effect of Feru-guard 100M on amyloid-beta deposition in individuals with mild cognitive impairment
- Trial, AD, NA
*Aβ∅, *BrainVol∅, *cognitive∅,
6866- FA,  Ang,    Effects of Ferulic Acid and Angelica archangelica Extract (Feru-guard ®) on Mild Cognitive Impairment: A Multicenter, Randomized, Double-Blind, Placebo-Controlled Prospective Trial
- Trial, AD, NA
*cognitive↑, *neuroP↑, *AChE↓, *Dose↝, *Aβ↓,
6883- FA,  Ang,    Effect of ferulic acid and Angelica archangelica extract on behavioral and psychological symptoms of dementia in frontotemporal lobar degeneration and dementia with Lewy bodies
- Trial, AD, NA
*Dose↝, *neuroP↑,
6962- FA,  VitB12,    Effects of Folic Acid and Vitamin B12, Alone and in Combination on Cognitive Function and Inflammatory Factors in the Elderly with Mild Cognitive Impairment: A Single-blind Experimental Design
- Trial, AD, NA
*Hcy/homoC↝, *IL6↓, *TNF-α↓, *MCP1/CCL2↝, *eff↑, *cognitive↑, *Inflam↓,
6951- FA,    Folic acid supplementation improves cognitive function by reducing the levels of peripheral inflammatory cytokines in elderly Chinese subjects with MCI
- Trial, AD, NA
*Dose↝, *cognitive↑, *Hcy/homoC↓, *IL6↓, *TNF-α↓,
6950- FA,  VitB12,    Effects of Folic Acid and Vitamin B12 Supplementation on Cognitive Impairment and Inflammation in Patients with Alzheimer's Disease: A Randomized, Single-Blinded, Placebo-Controlled Trial
- Trial, AD, NA
*Dose↝, *cognitive?,
6949- FA,  VitB12,    A controlled trial of homocysteine lowering and cognitive performance
- Trial, AD, NA
*Hcy/homoC↓, *cognitive∅,
6948- FA,  VitB12,    A randomized placebo controlled trial of homocysteine lowering to reduce cognitive decline in older demented people
- Trial, AD, NA
*Dose↝, *Hcy/homoC↓, *cognitive∅,
6947- FA,    Homocysteine-lowering by B vitamins slows the rate of accelerated brain atrophy in mild cognitive impairment: a randomized controlled trial
- Trial, AD, NA
*Hcy/homoC↓, *cognitive↑,
6954- FA,    Folic acid as a potential therapeutic agent for Alzheimer's disease: Effects on inflammatory cytokines, amyloid deposition, and neurotransmitter metabolism
- Trial, AD, NA
*Inflam↓, *Aβ↓, *IL1β↓, *IL6↓, *TNF-α↓, *tau↓, *GABA↑, *5HT↑, *Ach↑, *Albumin↑, *HemoG↑, *neuroP↑, *Hcy/homoC↓,
6956- FA,  VitB12,    A randomized placebo-controlled trial of using B vitamins to prevent cognitive decline in older mild cognitive impairment patients
- Trial, AD, NA
*Dose↝, *Hcy/homoC↓, *cognitive↑, *eff↓,
6961- FA,  VitB12,  VitB6,  Silicon,  Alum  B Vitamins Prevent Iron-Associated Brain Atrophy and Domain-Specific Effects of Iron, Copper, Aluminum, and Silicon on Cognition in Mild Cognitive Impairment
- Trial, AD, NA
*BrainVol↝, *cognitive↝, *cognitive↑, *Dose↝, *other↝, *Hcy/homoC↓, *Risk↓, *BrainVol∅, *BrainVol↑, *other↝, *cognitive↑, *cognitive↑, *other↝, *Risk↝,
4070- FA,    Folic Acid Supplementation Mitigates Alzheimer's Disease by Reducing Inflammation: A Randomized Controlled Trial
- Trial, AD, NA
*cognitive↑, *Aβ↓, *TNF-α↓, *Inflam↓,
4064- FA,  VitB6,  VitB12,    High-dose B vitamin supplementation and cognitive decline in Alzheimer disease: a randomized controlled trial
- Trial, AD, NA
*Hcy/homoC↓, *cognitive∅,
4074- FA,  VitB12,    Associations between Alzheimer's disease and blood homocysteine, vitamin B12, and folate: a case-control study
- Trial, AD, NA
*cognitive↑, *Hcy/homoC↓, *other↝, *other↝,
4044- FA,    Effect of 3-year folic acid supplementation on cognitive function in older adults in the FACIT trial: a randomised, double blind, controlled trial
- Trial, AD, NA
*Hcy/homoC↓, *memory↑, *cognitive↑,
1914- Fer,  VitC,  TMZ,  Rad,    Pharmacologic Ascorbate and Ferumoxytol Combined with Temozolomide and Radiation Therapy for the Treatment of Newly Diagnosed Glioblastoma
- Trial, GBM, NA
eff↑,
6920- FIS,    A phase II randomized placebo-controlled study of fisetin to improve physical function in breast cancer survivors: the TROFFi study rationale and trial design
- Trial, BC, NA
Dose↝, cellSen?,
6876- Flav,    Flavonoid-rich orange juice is associated with acute improvements in cognitive function in healthy middle-aged males
- Trial, AD, NA
*cognitive↑, *motorD↑, *other?,
4121- FLS,    Sensory-Evoked 40-Hz Gamma Oscillation Improves Sleep and Daily Living Activities in Alzheimer’s Disease Patients
- Trial, AD, NA
*cognitive↑, *Sleep↑,
6931- FLS,    Gamma frequency sensory stimulation in mild probable Alzheimer's dementia patients: Results of feasibility and pilot studies
- Trial, AD, NA
*tau↓, *Aβ↓, *other↝, *other↑, *memory↑, *other↑,
6933- FLS,  AudGS,    Gamma sensory stimulation in mild Alzheimer's dementia: An open-label extension study
- Trial, AD, NA
*Dose↝, *toxicity↓, *cognitive↑,
6932- FLS,    Safety, Feasibility, and Potential Clinical Efficacy of 40 Hz Invisible Spectral Flicker versus Placebo in Patients with Mild-to-Moderate Alzheimer's Disease: A Randomized, Placebo-Controlled, Double-Blinded, Pilot Study
- Trial, AD, NA
*toxicity↓,
7015- Fuc,    Effects of Ingesting Fucoidan Derived from Cladosiphon okamuranus Tokida on Human NK Cells: A Randomized, Double-Blind, Parallel-Group, Placebo-Controlled Pilot Study
- Trial, Nor, NA
*NK cell↑, *toxicity↓,
7018- Fuc,    Absorption Study of Mozuku Fucoidan in Japanese Volunteers
- Trial, Nor, NA
*Dose↝, *BioAv↝, *eff↝, *Inflam↓, *AntiThr↑, angioG↓, *AntiViral↑, *AntiTum↑, *antiOx↓, *BioAv↝,
7023- Fuc,    The Use of Oligo Fucoidan in Cancer Bearing Dogs Undergoing Chemotherapy: A Double-Blinded Study
- Trial, Var, NA
QoL∅, QoL↑,
7001- Fuc,    Fucoidan reduces the toxicities of chemotherapy for patients with unresectable advanced or recurrent colorectal cancer
- Trial, CRC, NA
fatigue↓, eff↑, OS↑,
7000- Fuc,    Efficacy of Low-Molecular-Weight Fucoidan as a Supplemental Therapy in Metastatic Colorectal Cancer Patients: A Double-Blind Randomized Controlled Trial
- Trial, CRC, NA
DCR↑, OS∅, PFS∅, ORR∅, AEs∅, QoL∅,
6999- Fuc,    Fucoidan Improves Tumour Control and Liver Function in TACE for Unresectable Hepatocellular Carcinoma: A Randomised Trial
- Trial, HCC, NA
hepatoP↑, toxicity↓,
7002- Fuc,    The Auxiliary Effects of Low-Molecular-Weight Fucoidan in Locally Advanced Rectal Cancer Patients Receiving Neoadjuvant Concurrent Chemoradiotherapy Before Surgery: A Double-Blind, Randomized, Placebo-Controlled Study
- Trial, CRC, NA
fatigue↓, GutMicro↑,
7040- GA,    Effects of gallic acid on acrylamide-induced endoplasmic reticulum stress, neuroinflammation and neuronal apoptosis in rats
- Trial, AD, NA
*SOD↑, *GSH↑, *GPx↑, *Catalase↑, *MDA↓, *TNF-α↓, *IL1β↓, *BAX↓, *Casp3↓, *BDNF↑, *NRF2↑, *HO-1↑,
7072- GABA,  CHOC,    Psychological stress-reducing effect of chocolate enriched with gamma-aminobutyric acid (GABA) in humans: assessment of stress using heart rate variability and salivary chromogranin A
- Trial, Nor, NA
*Dose↝, *Stress↓,
7071- GABA,    Oral intake of γ-aminobutyric acid affects mood and activities of central nervous system during stressed condition induced by mental tasks
- Trial, Nor, NA
*memory↑, *BP↓, *Dose↝, *Stress↓,
7075- GABA,    Effects of γ-aminobutyric acid supplementation on glucose control in adults with prediabetes: A double-blind, randomized, placebo-controlled trial
- Trial, Diabetic, NA
*Dose↝, *glucose∅,
7074- GABA,    Effect of oral γ-aminobutyric acid (GABA) administration on sleep and its absorption in humans
- Trial, Nor, NA
*Sleep↑,
7076- GABA,    Anti-hypertensive effect of gamma-aminobutyric acid (GABA)-rich Chlorella on high-normal blood pressure and borderline hypertension in placebo-controlled double blind study
- Trial, Nor, NA
*Dose↝, *BP↓, *eff↑,
7077- GABA,    GABA Supplementation, Increased Heart-Rate Variability, Emotional Response, Sleep Efficiency and Reduced Depression in Sedentary Overweight Women Undergoing Physical Exercise: Placebo-Controlled, Randomized Clinical Trial
- Trial, Nor, NA
*Sleep↑, *Dose↝, *other↝,
7073- GABA,    Safety and Efficacy of Gamma-Aminobutyric Acid from Fermented Rice Germ in Patients with Insomnia Symptoms: A Randomized, Double-Blind Trial
- Trial, Nor, NA
*Sleep↑,
7061- GamB,    An open-labeled, randomized, multicentered, phase IIa study for advanced cancer treatment by gambogic acid injection (THS)
- Trial, Var, NA
ORR↑, DCR↑, *toxicity↓,
7054- GamB,    An open-labeled, randomized, multicenter phase IIa study of gambogic acid injection for advanced malignant tumors
- Trial, Var, NA
Dose↝, DCR↝,
7187- GBE,    Ginkgo biloba for prevention of dementia: a randomized controlled trial
- Trial, AD, NA
*Dose↝, Risk∅, eff∅,
7188- GBE,    Efficacy and tolerability of a once daily formulation of Ginkgo biloba extract EGb 761® in Alzheimer's disease and vascular dementia: results from a randomised controlled trial
- Trial, AD, NA
*Dose↝, *cognitive↑,
7189- GBE,    Clinical and genomic safety of treatment with Ginkgo biloba L. leaf extract (IDN 5933/Ginkgoselect®Plus) in elderly: a randomised placebo-controlled clinical trial [GiBiEx]
- Trial, NA, NA
*Dose↝, *toxicity↓,
7130- Ge-132,    Phase I dose-escalation trial to repurpose propagermanium, an oral CCL2 inhibitor, in patients with breast cancer
- Trial, BC, NA
IL6↓, TumMeta↓, Dose↝, MCP1/CCL2↓,
7128- Ge-132,    Pharmacokinetics of germanium after po beta-carboxyethylgermanium sesquioxide in 24 Chinese volunteers
- Trial, Nor, NA
*Half-Life↝,
7126- Ge-132,    Immune activation of Bio-Germanium in a randomized, double-blind, placebo-controlled clinical trial with 130 human subjects: Therapeutic opportunities from new insights
- Trial, Nor, NA
AntiTum↑, AntiCan↑, *AntiAge↑, *AntiViral↑, *Inflam↓, *NK cell↑, *Imm↑, *TNF-α↑,
7109- GEN,    Single- and multiple-dose pharmacokinetics of genistein capsules in healthy chinese subjects: A phase I, randomized, open-label study
- Trial, Nor, NA
*Dose↝, *BioAv↝, *BioAv↝, *BioAv↝,
7106- GEN,  VitD3,    Phase IIa, randomized placebo-controlled trial of single high dose cholecalciferol (vitamin D3) and daily Genistein (G-2535) versus double placebo in men with early stage prostate cancer undergoing prostatectomy
- Trial, Pca, NA
Dose↝, toxicity↓, VitD↑, AR↝,
7107- GEN,    Inhibition of prostaglandin synthesis and actions by genistein in human prostate cancer cells and by soy isoflavones in prostate cancer patients
- Trial, Pca, NA - in-vitro, Pca, LNCaP - in-vitro, Pca, PC3
COX2↓, P21↑, PGE2↓, other↑, Dose↝,
7105- GEN,    Effects of genistein supplementation on genome‑wide DNA methylation and gene expression in patients with localized prostate cancer
- Trial, Pca, NA
Risk↓, Myc↓, PTEN↑, Dose↝, NOTCH3↑, JAG1↑, ADCY4↑, NEU1↑,

Showing Research Papers: 151 to 200 of 334
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* indicates research on normal cells as opposed to diseased cells
Total Research Paper Matches: 334

Pathway results for Effect on Cancer / Diseased Cells:


NA, unassigned(tgid=0) ⓘ

ADCY4↑, 1,   AEs∅, 1,   DCR↑, 2,   DCR↝, 1,   JAG1↑, 1,   NEU1↑, 1,   ORR↑, 1,   ORR∅, 1,   PFS∅, 1,  

Cell Death(tgid=5) ⓘ

Myc↓, 1,  

Transcription & Epigenetics(tgid=7) ⓘ

other↑, 1,  

Cell Cycle & Senescence(tgid=11) ⓘ

P21↑, 1,  

Proliferation, Differentiation & Cell State(tgid=12) ⓘ

NOTCH3↑, 1,   PTEN↑, 1,  

Migration(tgid=13) ⓘ

TumMeta↓, 1,  

Angiogenesis & Vasculature(tgid=14) ⓘ

angioG↓, 1,  

Immune & Inflammatory Signaling(tgid=16) ⓘ

cellSen?, 1,   COX2↓, 1,   IL6↓, 1,   MCP1/CCL2↓, 1,   PGE2↓, 1,   VitD↑, 1,  

Hormonal & Nuclear Receptors(tgid=20) ⓘ

AR↝, 1,  

Drug Metabolism & Resistance(tgid=21) ⓘ

Dose↝, 6,   eff↑, 2,   eff∅, 1,  

Clinical Biomarkers(tgid=22) ⓘ

AR↝, 1,   GutMicro↑, 1,   IL6↓, 1,   Myc↓, 1,   VitD↑, 1,  

Functional Outcomes(tgid=23) ⓘ

AntiCan↑, 1,   AntiTum↑, 1,   fatigue↓, 2,   hepatoP↑, 1,   OS↑, 1,   OS∅, 1,   QoL↑, 1,   QoL∅, 2,   Risk↓, 1,   Risk∅, 1,   toxicity↓, 2,  
Total Targets: 42

Pathway results for Effect on Normal Cells:


NA, unassigned(tgid=0) ⓘ

Stress↓, 2,  

Redox & Oxidative Stress(tgid=1) ⓘ

antiOx↓, 1,   Catalase↑, 1,   GPx↑, 1,   GSH↑, 1,   HO-1↑, 1,   MDA↓, 1,   NRF2↑, 1,   SOD↑, 1,  

Core Metabolism/Glycolysis(tgid=4) ⓘ

glucose∅, 1,  

Cell Death(tgid=5) ⓘ

BAX↓, 1,   Casp3↓, 1,  

Transcription & Epigenetics(tgid=7) ⓘ

Ach↑, 1,   AntiThr↑, 1,   other?, 1,   other↑, 2,   other↝, 7,  

Immune & Inflammatory Signaling(tgid=16) ⓘ

IL1β↓, 2,   IL6↓, 3,   Imm↑, 1,   Inflam↓, 5,   MCP1/CCL2↝, 1,   NK cell↑, 2,   TNF-α↓, 5,   TNF-α↑, 1,  

Synaptic & Neurotransmission(tgid=18) ⓘ

5HT↑, 1,   AChE↓, 1,   BDNF↑, 1,   BrainVol↑, 1,   BrainVol↝, 1,   BrainVol∅, 2,   GABA↑, 1,   tau↓, 2,  

Protein Aggregation(tgid=19) ⓘ

Aβ↓, 4,   Aβ∅, 1,  

Drug Metabolism & Resistance(tgid=21) ⓘ

BioAv↝, 5,   Dose↝, 18,   eff↓, 1,   eff↑, 2,   eff↝, 1,   Half-Life↝, 1,  

Clinical Biomarkers(tgid=22) ⓘ

Albumin↑, 1,   BP↓, 2,   Hcy/homoC↓, 10,   Hcy/homoC↝, 1,   HemoG↑, 1,   IL6↓, 3,  

Functional Outcomes(tgid=23) ⓘ

AntiAge↑, 1,   AntiTum↑, 1,   cognitive?, 1,   cognitive↑, 15,   cognitive↝, 1,   cognitive∅, 4,   memory↑, 3,   motorD↑, 1,   neuroP↑, 3,   Risk↓, 1,   Risk↝, 1,   Sleep↑, 4,   toxicity↓, 5,  

Infection & Microbiome(tgid=24) ⓘ

AntiViral↑, 2,  
Total Targets: 61

Query results interpretion may depend on "conditions" listed in the research papers.
Such Conditions may include : 
  -low or high Dose
  -format for product, such as nano of lipid formations
  -different cell line effects
  -synergies with other products 
  -if effect was for normal or cancerous cells

Filter Conditions: Pro/AntiFlg:%  IllCat:%  CanType:%  Cells:%  prod#:%  Target#:%  State#:%  Dir#:%
  wNotes=0  sortOrder:rid,rpid

 

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