| Source: |
| Type: |
| Toxicity |
| 5698- | BRU, | Brusatol suppresses STAT3-driven metastasis by downregulating epithelial-mesenchymal transition in hepatocellular carcinoma |
| - | in-vitro, | HCC, | NA |
| 5708- | Brut, | Clinical application of bergamot (Citrus bergamia) for reducing high cholesterol and cardiovascular disease markers |
| - | Review, | Nor, | NA |
| 6542- | BSB, | Health Benefits, Pharmacological Effects, Molecular Mechanisms, and Therapeutic Potential of α-Bisabolol |
| - | Review, | Var, | NA | - | Review, | Park, | NA | - | Review, | AD, | NA |
| - | in-vivo, | Nor, | NA |
| 6556- | BSB, | A Comprehensive Study of Therapeutic Applications of Chamomile |
| - | Review, | Nor, | NA | - | Review, | AD, | NA | - | Review, | Park, | NA | - | Review, | Stroke, | NA |
| 7978- | BUL, | Synthesis and Cytotoxic Property of Annonaceous Acetogenin Glycoconjugates |
| - | in-vitro, | Cerv, | HeLa | - | in-vitro, | Lung, | A549 | - | in-vitro, | Liver, | HepG2 |
| 7975- | BUL, | Bullatacin--in vivo and in vitro experience in an ovarian cancer model |
| - | in-vitro, | Ovarian, | OVCAR-3 |
| 7976- | BUL, | Antitumor activity and toxicity relationship of annonaceous acetogenins |
| - | in-vitro, | HCC, | H22 |
| 5736- | Buty, | Clinical and pharmacologic study of tributyrin: an oral butyrate prodrug |
| - | Trial, | Var, | NA |
| 5874- | CA, | Carnosic Acid Mediates Production of Reactive Oxygen Species to Regulate Mitogen-Activated Protein Kinase Pathway Phosphorylation and Induce Apoptosis in Human Breast Cancer Cells |
| - | vitro+vivo, | BC, | T47D | - | in-vitro, | BC, | MCF10 |
| 5829- | CAP, | Anti-cancer activity of capsaicin and its analogs in gynecological cancers |
| - | Review, | Var, | NA |
| 5844- | CAP, | Non-pungent long chain capsaicin-analogs arvanil and olvanil display better anti-invasive activity than capsaicin in human small cell lung cancers |
| - | in-vitro, | Lung, | DMS114 |
| 2014- | CAP, | Role of Mitochondrial Electron Transport Chain Complexes in Capsaicin Mediated Oxidative Stress Leading to Apoptosis in Pancreatic Cancer Cells |
| - | in-vitro, | PC, | Bxpc-3 | - | in-vitro, | Nor, | HPDE-6 | - | in-vivo, | PC, | AsPC-1 |
| 8695- | CAP, | Advances in cold atmospheric plasma therapy for cancer |
| - | Review, | Var, | NA |
| 8699- | CAP, | Antitumor effects of plasma‑activated solution on a murine melanoma model in vivo and in vitro |
| - | vitro+vivo, | Melanoma, | A375 |
| 5885- | CAR, | Inhibition of TRPM7 by carvacrol suppresses glioblastoma cell proliferation, migration and invasion |
| - | in-vitro, | GBM, | U87MG | - | in-vitro, | Nor, | HEK293 |
| 5883- | CAR, | Safety and tolerability of carvacrol in healthy subjects: a phase I clinical study |
| - | Trial, | Nor, | NA |
| 5881- | CAR, | Carvacrol—A Natural Phenolic Compound with Antimicrobial Properties |
| - | Review, | Nor, | NA |
| - | in-vitro, | BC, | MCF7 | - | in-vitro, | BC, | MDA-MB-231 |
| 5889- | CAR, | Effect of carvacrol on pulmonary function tests, and total and differential white blood cell counts in healthy volunteers: A randomized clinical trial |
| - | Trial, | Nor, | NA |
| 5927- | CAR, | Neuroprotective Potential and Underlying Pharmacological Mechanism of Carvacrol for Alzheimer’s and Parkinson’s Diseases |
| - | Review, | AD, | NA | - | Review, | Park, | NA |
| 5926- | CAR, | An Updated Review of Research into Carvacrol and Its Biological Activities |
| - | Review, | Nor, | NA | - | Review, | AD, | NA | - | Review, | Asthma, | NA |
| 5862- | carbop, | Cisplatin, | Molecular Mechanisms of Resistance and Toxicity Associated with Platinating Agents |
| - | Review, | Var, | NA |
| 3878- | Carno, | Safety and Efficacy Evaluation of Carnosine, An Endogenous Neuroprotective Agent for Ischemic Stroke |
| - | in-vivo, | Stroke, | NA |
| 3877- | Carno, | Carnosine, diabetes and Alzheimer's disease |
| - | Review, | AD, | NA |
| 3869- | Carno, | Carnosine, Small but Mighty—Prospect of Use as Functional Ingredient for Functional Food Formulation |
| - | Review, | AD, | NA | - | Review, | Stroke, | NA |
| 5929- | Catechins, | Phase I trial of oral green tea extract in adult patients with solid tumors |
| - | Trial, | Var, | NA |
| 5917- | Cats, | Uncaria tomentosa for Reducing Side Effects Caused by Chemotherapy in CRC Patients: Clinical Trial |
| - | Trial, | CRC, | NA |
| 9134- | CC, | Camu camu plus nivolumab/ipilimumab (N/I) as first-line therapy for metastatic renal cell carcinoma (mRCC): A randomized phase I trial |
| - | Trial, | RCC, | NA |
| 5954- | CEL, | The molecular mechanisms of celecoxib in tumor development |
| - | Review, | Var, | NA |
| 5953- | Cela, | CUR, | The Combination of Celastrol and Curcumin Enhances the Antitumor Effect in Nasopharyngeal Carcinoma by Inducing Ferroptosis |
| - | vitro+vivo, | NPC, | NA |
| 5946- | Cela, | The anti-cancer mechanism of Celastrol by targeting JAK2/STAT3 signaling pathway in gastric and ovarian cancer |
| - | in-vitro, | Var, | NA |
| 5947- | Cela, | Recent advances in drug delivery of celastrol for enhancing efficiency and reducing the toxicity |
| - | Review, | Var, | NA |
| 5948- | Cela, | Recent Trends in anti-tumor mechanisms and molecular targets of celastrol |
| - | Review, | Var, | NA |
| 6638- | Cen, | Prolonged Treatment with Centella asiatica Improves Memory, Reduces Amyloid-β Pathology, and Activates NRF2-Regulated Antioxidant Response Pathway in 5xFAD Mice |
| - | in-vivo, | AD, | NA |
| 6645- | Cen, | Can Asiatic Acid from Centella asiatica Be a Potential Remedy in Cancer Therapy?—A Review |
| - | Review, | Var, | NA |
| 6646- | Cen, | Effectiveness of Gotu Kola Extract 750 mg and 1000 mg Compared with Folic Acid 3 mg in Improving Vascular Cognitive Impairment after Stroke |
| - | Trial, | Stroke, | NA |
| 6013- | CGA, | Advances in Pharmacological Properties, Molecular Mechanisms, and Bioavailability Strategies of Chlorogenic Acid in Cardiovascular Diseases Therapy |
| - | Review, | CardioV, | NA |
| 6008- | CGA, | Risk Assessment of Chlorogenic and Isochlorogenic Acids in Coffee By-Products |
| - | Review, | Nor, | NA |
| 6024- | CGA, | Phase I study of chlorogenic acid injection for recurrent high-grade glioma with long-term follow-up |
| - | Trial, | GBM, | NA |
| 6043- | CGA, | SeNPs, | Enhanced Effect of Combining Chlorogenic Acid on Selenium Nanoparticles in Inhibiting Amyloid β Aggregation and Reactive Oxygen Species Formation In Vitro |
| - | in-vitro, | AD, | NA |
| 7174- | CHA, | Inhibition of SUV39H1 reduces tumor angiogenesis via Notch1 in oral squamous cell carcinoma |
| - | vitro+vivo, | OS, | OS-RC-2 |
| 7173- | CHA, | Natural compound chaetocin induced DNA damage and apoptosis through reactive oxygen species-dependent pathways in A549 lung cancer cells and in vitro evaluations |
| - | in-vitro, | Lung, | A549 |
| 7163- | CHA, | The anticancer effects of chaetocin are independent of programmed cell death and hypoxia, and are associated with inhibition of endothelial cell proliferation |
| - | in-vitro, | Lung, | A549 | - | in-vitro, | OS, | U2OS | - | in-vitro, | CRC, | HCT116 | - | in-vitro, | CRC, | HeLa | - | in-vivo, | Ovarian, | SKOV3 |
| 7159- | CHA, | ROS-mediated inactivation of the PI3K/AKT pathway is involved in the antigastric cancer effects of thioredoxin reductase-1 inhibitor chaetocin |
| - | vitro+vivo, | GC, | HGC27 | - | in-vitro, | GC, | AGS | - | in-vitro, | GC, | BGC-823 | - | in-vitro, | GC, | SGC-7901 | - | in-vitro, | Nor, | HEK293 |
| 6025- | Chit, | Glycated chitosan as a new non-toxic immunological stimulant |
| - | vitro+vivo, | Var, | HeLa |
| 6000- | Chit, | Chitosan in Modern Pharmacotherapy: From Drug Encapsulation to Targeted Delivery Systems |
| - | Review, | Var, | NA |
| 6001- | Chit, | Recent advances in engineering chitosan-based nanoplatforms in biotherapeutic multi-delivery for multi-targeted disease treatments: Promises and outlooks |
| - | Review, | Var, | HepG2 | - | Review, | AD, | NA |
| 5982- | Chit, | Chitosan Nanoparticles-Based Cancer Drug Delivery: Application and Challenges |
| - | Review, | Var, | NA |
| 5987- | Chit, | Chitin, Chitosan, and Glycated Chitosan Regulate Immune Responses: The Novel Adjuvants for Cancer Vaccine |
| - | Review, | Var, | NA |
Query results interpretion may depend on "conditions" listed in the research papers. Such Conditions may include : -low or high Dose -format for product, such as nano of lipid formations -different cell line effects -synergies with other products -if effect was for normal or cancerous cells
Filter Conditions: Pro/AntiFlg:% IllCat:% CanType:% Cells:% prod#:% Target#:1025 State#:% Dir#:%
wNotes=0 sortOrder:rid,rpid