Dose Cancer Research Results

Dose, Dosage: Click to Expand ⟱
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Drug dosage vs efficacy, and actual dosage number of research papers.
Scientific Papers found: Click to Expand⟱
5824- CAP,    Pharmacokinetic and the effect of capsaicin in Capsicum frutescens on decreasing plasma glucose level
- Study, Diabetic, NA
*glucose↓, *Insulin↑, *Dose↑, *AntiDiabetic↑,
5846- CAP,    Capsaicin Alters the Expression of Genetic and Epigenetic Molecules In Hepatocellular Carcinoma Cell
- in-vitro, HCC, HepG2
Dose↝, miR-126↑, Ki-67↓, PI3K↓, mTOR↓, Akt↑, eff↑, Casp3↑,
1518- CAP,    Capsaicin-mediated tNOX (ENOX2) up-regulation enhances cell proliferation and migration in vitro and in vivo
- in-vitro, CRC, HCT116
ENOX2↑, TumCP↑, TumCMig↑, Dose?, eff↑,
1517- CAP,    Capsaicin Inhibits Multiple Bladder Cancer Cell Phenotypes by Inhibiting Tumor-Associated NADH Oxidase (tNOX) and Sirtuin1 (SIRT1)
- in-vitro, Bladder, TSGH8301 - in-vitro, CRC, T24/HTB-9
ENOX2↓, TumCCA↑, ERK↓, p‑FAK↓, p‑pax↓, TumCMig↓, EMT↓, SIRT1↓, Dose∅, ROS↑, MMP↓, Bcl-2↓, Bak↑, cl‑PARP↑, Casp3↑, SIRT1↓, ac‑P53↑, BIM↑, p‑RB1↓, cycD1/CCND1↓, Dose∅, β-catenin/ZEB1↓, N-cadherin↓, E-cadherin↑,
2014- CAP,    Role of Mitochondrial Electron Transport Chain Complexes in Capsaicin Mediated Oxidative Stress Leading to Apoptosis in Pancreatic Cancer Cells
- in-vitro, PC, Bxpc-3 - in-vitro, Nor, HPDE-6 - in-vivo, PC, AsPC-1
ROS↑, *ROS∅, selectivity↑, compI↓, compIII↓, eff↑, selectivity↑, ATP↓, Cyt‑c↑, Casp9↑, Casp3↑, MMP↓, SOD↓, GSH/GSSG↓, Apoptosis↑, *toxicity∅, GSH↓, Catalase↓, GPx↓, Dose↝,
2015- CAP,  CUR,  urea,    Anti-cancer Activity of Sustained Release Capsaicin Formulations
- Review, Var, NA
AntiCan↑, TumCG↓, angioG↓, TumMeta↓, BioAv↓, BioAv↓, BioAv↑, selectivity↑, EPR↑, eff↓, ChemoSen↑, Dose∅, Half-Life∅, eff↑,
5879- CAR,    Pharmacokinetic analysis of thymol, carvacrol and diallyl disulfide after intramammary and topical applications in healthy organic dairy cattle
- in-vivo, Nor, NA
*Dose↝, Half-Life↝, Half-Life↝, Half-Life↝,
5886- CAR,    Inhibition of TRPM7 with carvacrol suppresses glioblastoma functions in vivo
- in-vivo, GBM, U87MG - in-vivo, GBM, U251
TRPM7↓, TumVol↓, p‑Akt↓, p‑GSK‐3β↑, Dose↝,
5883- CAR,    Safety and tolerability of carvacrol in healthy subjects: a phase I clinical study
- Trial, Nor, NA
*Dose↝, *HDL↓, *Bil↓, *Iron↓, *toxicity↓,
5881- CAR,    Carvacrol—A Natural Phenolic Compound with Antimicrobial Properties
- Review, Nor, NA
*Bacteria↓, *Inflam↓, *SOD↑, *GPx↑, *GSR↑, *Catalase↑, *toxicity↓, *Pain↓, *other↑, *cardioP↑, *RenoP↑, *neuroP↑, *antiOx↑, *AntiDiabetic↑, *hepatoP↑, *Obesity↓, *AntiAg↑, *BioAv↓, BioAv↝, *OS↑, MMP↓, ROS↑, *MDA↓, *lipid-P↓, *COX2↓, *Dose↝,
5880- CAR,    In vitro and in vivo antitumor potential of carvacrol nanoemulsion against human lung adenocarcinoma A549 cells via mitochondrial mediated apoptosis
- vitro+vivo, Lung, A549 - in-vitro, Nor, BEAS-2B - in-vitro, Lung, PC9
Dose↝, mt-ROS↑, p‑JNK↑, BAX↑, Cyt‑c↑, Casp↑, AntiTum↑, ER Stress↑, LDH↑, selectivity↑, Apoptosis↑, DNAdam↑, IRE1↑, XBP-1↑, CHOP↓, p‑eIF2α↓, GRP78/BiP↓, Ca+2↑, MMP↓, Bcl-2↓, Casp3↑, Casp9↑, eff↓, TumW↓, Weight↑, eff↑, eff↑,
5908- CAR,    Carvacrol improves neurological function by inhibiting TRPM7-mediated BBB disruption and hemorrhage after TBI
- in-vivo, Nor, NA
*TRPM7↓, *BBB↑, *motorD↑, *cognitive↑, *Dose↝, MMPs↓,
5910- CAR,    Oregano Phytocomplex Induces Programmed Cell Death in Melanoma Lines via Mitochondria and DNA Damage
- in-vitro, Melanoma, B16-F10 - NA, NA, A375
ROS↑, TumCP↓, Apoptosis↑, Necroptosis↑, mtDam↑, DNAdam↑, selectivity↑, Dose↝, MPT↓,
5894- CAR,    Targeting Gastrointestinal Cancers with Carvacrol: Mechanistic Insights and Therapeutic Potential
- Review, Var, NA
AntiCan↑, Apoptosis↑, Inflam↓, angioG↓, TumMeta↓, selectivity↑, BioAv↑, ChemoSen↑, Dose↝, TumCP↓, hepatoP↑, Casp3↑, Casp9↑, Bcl-2↓, ROS↑, GSH↓, BAX↑, Casp7↑, Casp8↑, Cyt‑c↑, Fas↑, FADD↑, P53↑, Bcl-2↓, TumMeta↓, TumCMig↓, TumCI↓, E-cadherin↑, TIMP2↑, TIMP3↑, N-cadherin↓, ZEB2↓, *lipid-P↓, *AST↓, *ALAT↓, *ALP↓, *LDH↓, *SOD↑, *Catalase↑, *GPx↑, *GSR↑, selectivity↑, cl‑PARP↑, ERK↓, p38↑, OS↑, AFP↓, COX2↓, VEGF↓, PCNA↓, Ki-67↓, TNF-α↓, BioAv↓,
5892- CAR,  SRF,    Carvacrol potentiates immunity and sorafenib anti-cancer efficacy by targeting HIF-1α/STAT3/ FGL1 pathway: in silico and in vivo study
- in-vivo, HCC, NA
Hif1a↓, AFP↑, hepatoP↑, STAT3↓, JAK2↓, *CD8+↑, ChemoSen↑, Dose↝, angioG↓,
5891- CAR,  SRF,    Carvacrol enhances anti-tumor activity and mitigates cardiotoxicity of sorafenib in thioacetamide-induced hepatocellular carcinoma model through inhibiting TRPM7
- in-vivo, HCC, NA
eff↑, OS↑, hepatoP↑, AFP↓, NOTCH↓, cycD1/CCND1↓, Bcl-xL↑, Casp3↑, TRPM7↓, Dose↝,
5889- CAR,    Effect of carvacrol on pulmonary function tests, and total and differential white blood cell counts in healthy volunteers: A randomized clinical trial
- Trial, Nor, NA
*Dose↝, *toxicity∅,
5929- Catechins,    Phase I trial of oral green tea extract in adult patients with solid tumors
- Trial, Var, NA
Dose↑, toxicity↝,
5916- Cats,  Chemo,    Uncaria tomentosa—Adjuvant Treatment for Breast Cancer: Clinical Trial
- Trial, BC, NA
*DNAdam↓, Neut↓, eff↑, Imm↑, Dose↝,
5917- Cats,    Uncaria tomentosa for Reducing Side Effects Caused by Chemotherapy in CRC Patients: Clinical Trial
- Trial, CRC, NA
Dose↝, *DNArepair↑, toxicity↝, BioAv↝, eff∅,
5918- Cats,    Uncaria tomentosa (cat's claw) improves quality of life in patients with advanced solid tumors
- Trial, Var, NA
Dose↝, QoL↑, fatigue↓,
5813- CBD,    Pharmacokinetics of Cannabidiol: A Systematic Review and Meta-Regression Analysis
- Review, Var, NA
Dose↝, BioAv↑, BioAv↓, BioAv↑,
5960- CEL,    Phase II, Randomized, Placebo-Controlled Trial of Neoadjuvant Celecoxib in Men With Clinically Localized Prostate Cancer: Evaluation of Drug-Specific Biomarkers
- Trial, Pca, NA
eff∅, Dose↝, CardioT↑,
5959- CEL,    Celecoxib induces apoptosis in cervical cancer cells independent of cyclooxygenase using NF-κB as a possible target
- in-vitro, Cerv, HeLa
Apoptosis↑, Casp8↑, Casp9↑, cl‑BID↑, MMP↓, NF-kB↑, Dose⇅, chemoPv⇅, COX2↓,
5953- Cela,  CUR,    The Combination of Celastrol and Curcumin Enhances the Antitumor Effect in Nasopharyngeal Carcinoma by Inducing Ferroptosis
- vitro+vivo, NPC, NA
eff↑, TumCP↓, GPx4↓, eff↑, TumAuto↑, Ferroptosis↑, Dose↝, ACSL4↑, toxicity↓,
5940- Cela,    Celastrol Suppresses Angiogenesis-Mediated Tumor Growth through Inhibition of AKT/Mammalian Target of Rapamycin Pathway
- in-vivo, Pca, PC3
Dose↝, TumVol↓, TumW↓, angioG↓, VEGF↓, TumCMig↓, TumCP↓, TumCI↓, Akt↓, mTOR↓, P70S6K↓,
5952- Cela,    Celastrol attenuates Alzheimer’s disease-mediated learning and memory impairment by inhibiting endoplasmic reticulum stress-induced inflammation and oxidative stress
- in-vivo, AD, NA
*memory↑, *Inflam↓, *ROS↓, *ER Stress↓, *neuroP↑, *Dose↝, *MDA↓, *SOD↑, *Catalase↑, *Aβ↓, BACE↓, LRP1↑, RAGE↓,
5943- Cela,    Celastrol: A Spectrum of Treatment Opportunities in Chronic Diseases
- Review, Arthritis, NA - Review, IBD, NA - Review, AD, NA - Review, Park, NA
*other↝, *other↝, *CRP↓, *eff↝, *other↑, *CXCR4↓, *IL1β↓, *IL6↓, *IL17↓, *IL18↓, *TNF-α↓, *MMP9↓, *PGE2↓, *COX1↓, *COX2↓, *PI3K↓, *Akt↓, *other↑, TumCCA↑, Apoptosis↑, ROS↑, JNK↑, TumAuto↑, Hif1a↓, BNIP3↝, HSP90↓, Fas↑, FasL↑, ETC↓, VEGF↓, angioG↓, RadioS↑, *neuroP↑, *HSP70/HSPA5↑, *ROS↓, *MMP↑, *Cyt‑c↓, *Casp3↓, *Casp9↓, *MAPK↓, *Dose⇅, *HSPs↑, BioAv↓, Dose↝,
5970- CET,    Cetuximab
- Review, CRC, NA - Review, HNSCC, NA
EGFR↓, OS↑, QoL↑, Dose↝,
5967- CET,    FDA grants accelerated approval to adagrasib with cetuximab for KRAS G12C-mutated colorectal cancer
- Study, CRC, NA
eff↑, Dose↝,
6022- CGA,    Chlorogenic Acid: Recent Advances on Its Dual Role as a Food Additive and a Nutraceutical against Metabolic Syndrome
- Review, Nor, NA
*antiOx↑, *Inflam↓, *AntiDiabetic↑, *Obesity↓, *Wound Healing↑, *BP↓, *Dose↝, *ROS↓, *Fas↓, *HMG-CoA↓, *GutMicro↑,
6019- CGA,  immuno,    Combination immunotherapy of chlorogenic acid liposomes modified with sialic acid and PD-1 blockers effectively enhances the anti-tumor immune response and therapeutic effects
- in-vivo, Melanoma, NA
eff↑, Dose↝, AntiTum↑, eff↑,
6037- CGA,    Pharmacokinetics and brain penetration study of chlorogenic acid in rats
- in-vivo, AD, NA - in-vivo, Stroke, NA
*Dose↝, *eff↑, *BioAv↑, *eff↑,
6040- CGA,    Protective effect of chlorogenic acid on cognitive impairment in rats with early Alzheimer's disease via Wnt signaling pathway
- in-vivo, AD, NA
*neuroP↑, *Dose↝, *GSK‐3β↓, *tau↓, *β-catenin/ZEB1↑, *Wnt↑, *memory↑, *cognitive↑, *NRF2↑, *ROS↓,
6041- CGA,    Effect of Chlorogenic Acid Intake on Cognitive Function in the Elderly: A Pilot Study
- Trial, AD, NA
*Dose↝, *memory↑, *Risk↓, *cognitive↑, *Aβ↓, *antiOx↓, *motorD↑,
6043- CGA,  SeNPs,    Enhanced Effect of Combining Chlorogenic Acid on Selenium Nanoparticles in Inhibiting Amyloid β Aggregation and Reactive Oxygen Species Formation In Vitro
- in-vitro, AD, NA
*ROS↓, *Aβ↓, *BioAv↝, *BioAv↑, *Dose↝, *ROS↓, *H2O2↓, *toxicity↓,
6035- CGA,    Effect of Chlorogenic Acids on Cognitive Function in Mild Cognitive Impairment: A Randomized Controlled Crossover Trial
- Trial, Nor, NA
*Dose↝, *cognitive↑, *Risk↓, *AChE↓, *ROS↓,
6029- CGA,    Pharmacokinetics of chlorogenic acids absorbed in human plasma and their metabolites following oral ingestion of coffee drink
- Trial, Nor, NA
*Dose↝, *BioAv↑, *Half-Life↝,
6028- CGA,    Chlorogenic acids from green coffee extract are highly bioavailable in humans
- Trial, Nor, NA
*BioAv↑, *Dose↝,
6001- Chit,    Recent advances in engineering chitosan-based nanoplatforms in biotherapeutic multi-delivery for multi-targeted disease treatments: Promises and outlooks
- Review, Var, HepG2 - Review, AD, NA
TumVol↓, toxicity↓, Half-Life↑, eff↑, selectivity↑, Dose↝, *BDNF↑, *NRF2↑, *ROS↓, *neuroP↑, *memory↑, *cognitive↑, *Obesity↓,
6071- CHL,    First-in-human clinical trial of high-dose sodium copper chlorophyllin: Pharmacology and efficacy as a dual immunomodulatory/antiviral agent
- Trial, Nor, NA
*Dose↑, *toxicity↓, *Imm↑,
3701- Chol,    Lifelong choline supplementation ameliorates Alzheimer's disease pathology and associated cognitive deficits by attenuating microglia activation
- in-vivo, AD, NA
*Ach↑, *Aβ↓, *memory↑, *APP↓, *eff↑, *neuroP↑, *Dose↑,
2806- CHr,  Se,    Selenium-containing chrysin and quercetin derivatives: attractive scaffolds for cancer therapy
- in-vitro, Var, NA
eff↑, selectivity↑, Dose↝, TrxR↓, GSH↓, MMP↓, ROS↑, H2O2↑,
2784- CHr,    Chrysin targets aberrant molecular signatures and pathways in carcinogenesis (Review)
- Review, Var, NA
Apoptosis↑, TumCMig↓, *toxicity↝, ChemoSen↑, *BioAv↓, Dose↝, neuroP↑, *P450↓, *ROS↓, *HDL↑, *GSTs↑, *SOD↑, *Catalase↑, *MAPK↓, *NF-kB↓, *PTEN↑, *VEGF↑, ROS↑, MMP↓, Ca+2↑, selectivity↑, PCNA↓, Twist↓, EMT↓, CDKN1C↑, p‑STAT3↑, MMP2↓, MMP9↓, eff↑, cycD1/CCND1↓, hTERT/TERT↓, CLDN1↓, TumVol↓, OS↑, COX2↓, eff↑, CDK2↓, CDK4↓, selectivity↑, TumCCA↑, E-cadherin↑, HK2↓, HDAC↓,
1583- Citrate,    Extracellular citrate and metabolic adaptations of cancer cells
- Review, NA, NA
Warburg↓, OXPHOS↓, Dose∅, TumCP↓, ATP↓, eff↑, Apoptosis↑, TumCG↓, PFK1↓,
1586- Citrate,    Extracellular Citrate Is a Trojan Horse for Cancer Cells
- in-vitro, Liver, HepG2
Dose?, ac‑H4↓, lipidDe↓, ACLY↓, selectivity↑, *ACLY∅, Glycolysis↓, NADH↓, OAA↑, other↑,
1582- Citrate,    Clinical report: A patient with primary peritoneal mesothelioma that has improved after taking citric acid orally
- Case Report, PerC, NA
Dose∅, Weight↑, OS↑,
1581- Citrate,    Hypothesis proved. . .citric acid (citrate) does improve cancer:A case of a patient suffering from medullary thyroid cancer
- Case Report, Thyroid, NA
OS↑, Weight↑, Dose∅, eff↑,
1578- Citrate,    Understanding the Central Role of Citrate in the Metabolism of Cancer Cells and Tumors: An Update
- Review, Var, NA
TCA↑, FASN↑, Glycolysis↓, glucoNG↑, PFK1↓, PFK2↓, FBPase↑, TumCP↓, eff↑, ACLY↓, Dose↑, Casp3↑, Casp2↑, Casp8↑, Casp9↑, Bcl-xL↓, Mcl-1↓, IGF-1R↓, PI3K↓, Akt↓, mTOR↓, PTEN↑, ChemoSen↑, Dose?,
1576- Citrate,    Targeting citrate as a novel therapeutic strategy in cancer treatment
- Review, Var, NA
TCA↓, T-Cell↝, Glycolysis↓, PKM2↓, PFK2?, SDH↓, PDH↓, β-oxidation↓, CPT1A↓, FASN↑, Casp3↑, Casp2↑, Casp8↑, Casp9↑, cl‑PARP↑, Hif1a↓, GLUT1↓, angioG↓, Ca+2↓, ROS↓, eff↓, Dose↓, eff↑, Mcl-1↓, HK2↓, IGF-1R↓, PTEN↑, citrate↓, Dose∅, eff↑, eff↑, eff↑, eff↑,

Showing Research Papers: 151 to 200 of 571
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* indicates research on normal cells as opposed to diseased cells
Total Research Paper Matches: 571

Pathway results for Effect on Cancer / Diseased Cells:


Redox & Oxidative Stress ⓘ

Catalase↓, 1,   compI↓, 1,   ENOX2↓, 1,   ENOX2↑, 1,   Ferroptosis↑, 1,   GPx↓, 1,   GPx4↓, 1,   GSH↓, 3,   GSH/GSSG↓, 1,   H2O2↑, 1,   lipidDe↓, 1,   NADH↓, 1,   OXPHOS↓, 1,   ROS↓, 1,   ROS↑, 8,   mt-ROS↑, 1,   SOD↓, 1,   TrxR↓, 1,  

Mitochondria & Bioenergetics ⓘ

ATP↓, 2,   compIII↓, 1,   ETC↓, 1,   MMP↓, 7,   MPT↓, 1,   mtDam↑, 1,   SDH↓, 1,  

Core Metabolism/Glycolysis ⓘ

ACLY↓, 2,   ACSL4↑, 1,   citrate↓, 1,   CPT1A↓, 1,   FASN↑, 2,   FBPase↑, 1,   glucoNG↑, 1,   Glycolysis↓, 3,   HK2↓, 2,   LDH↑, 1,   OAA↑, 1,   PDH↓, 1,   PFK1↓, 2,   PFK2?, 1,   PFK2↓, 1,   PKM2↓, 1,   SIRT1↓, 2,   TCA↓, 1,   TCA↑, 1,   Warburg↓, 1,   β-oxidation↓, 1,  

Cell Death ⓘ

Akt↓, 2,   Akt↑, 1,   p‑Akt↓, 1,   Apoptosis↑, 8,   Bak↑, 1,   BAX↑, 2,   Bcl-2↓, 4,   Bcl-xL↓, 1,   Bcl-xL↑, 1,   cl‑BID↑, 1,   BIM↑, 1,   Casp↑, 1,   Casp2↑, 2,   Casp3↑, 8,   Casp7↑, 1,   Casp8↑, 4,   Casp9↑, 6,   Cyt‑c↑, 3,   FADD↑, 1,   Fas↑, 2,   FasL↑, 1,   Ferroptosis↑, 1,   hTERT/TERT↓, 1,   JNK↑, 1,   p‑JNK↑, 1,   Mcl-1↓, 2,   Necroptosis↑, 1,   p38↑, 1,  

Transcription & Epigenetics ⓘ

ac‑H4↓, 1,   other↑, 1,  

Protein Folding & ER Stress ⓘ

CHOP↓, 1,   p‑eIF2α↓, 1,   ER Stress↑, 1,   GRP78/BiP↓, 1,   HSP90↓, 1,   IRE1↑, 1,   XBP-1↑, 1,  

Autophagy & Lysosomes ⓘ

BNIP3↝, 1,   TumAuto↑, 2,  

DNA Damage & Repair ⓘ

DNAdam↑, 2,   P53↑, 1,   ac‑P53↑, 1,   cl‑PARP↑, 3,   PCNA↓, 2,  

Cell Cycle & Senescence ⓘ

CDK2↓, 1,   CDK4↓, 1,   cycD1/CCND1↓, 3,   p‑RB1↓, 1,   TumCCA↑, 3,  

Proliferation, Differentiation & Cell State ⓘ

EMT↓, 2,   ERK↓, 2,   p‑GSK‐3β↑, 1,   HDAC↓, 1,   IGF-1R↓, 2,   mTOR↓, 3,   NOTCH↓, 1,   P70S6K↓, 1,   PI3K↓, 2,   PTEN↑, 2,   STAT3↓, 1,   p‑STAT3↑, 1,   TRPM7↓, 2,   TumCG↓, 2,  

Migration ⓘ

Ca+2↓, 1,   Ca+2↑, 2,   CDKN1C↑, 1,   CLDN1↓, 1,   E-cadherin↑, 3,   p‑FAK↓, 1,   Ki-67↓, 2,   LRP1↑, 1,   MMP2↓, 1,   MMP9↓, 1,   MMPs↓, 1,   N-cadherin↓, 2,   p‑pax↓, 1,   RAGE↓, 1,   TIMP2↑, 1,   TIMP3↑, 1,   TumCI↓, 2,   TumCMig↓, 4,   TumCMig↑, 1,   TumCP↓, 6,   TumCP↑, 1,   TumMeta↓, 3,   Twist↓, 1,   ZEB2↓, 1,   β-catenin/ZEB1↓, 1,  

Angiogenesis & Vasculature ⓘ

angioG↓, 6,   EGFR↓, 1,   EPR↑, 1,   Hif1a↓, 3,   miR-126↑, 1,   VEGF↓, 3,  

Barriers & Transport ⓘ

GLUT1↓, 1,  

Immune & Inflammatory Signaling ⓘ

COX2↓, 3,   Imm↑, 1,   Inflam↓, 1,   JAK2↓, 1,   Neut↓, 1,   NF-kB↑, 1,   T-Cell↝, 1,   TNF-α↓, 1,  

Protein Aggregation ⓘ

BACE↓, 1,  

Drug Metabolism & Resistance ⓘ

BioAv↓, 5,   BioAv↑, 4,   BioAv↝, 2,   ChemoSen↑, 5,   Dose?, 3,   Dose↓, 1,   Dose↑, 2,   Dose⇅, 1,   Dose↝, 22,   Dose∅, 7,   eff↓, 3,   eff↑, 25,   eff∅, 2,   Half-Life↑, 1,   Half-Life↝, 3,   Half-Life∅, 1,   RadioS↑, 1,   selectivity↑, 12,  

Clinical Biomarkers ⓘ

AFP↓, 2,   AFP↑, 1,   EGFR↓, 1,   hTERT/TERT↓, 1,   Ki-67↓, 2,   LDH↑, 1,   RAGE↓, 1,  

Functional Outcomes ⓘ

AntiCan↑, 2,   AntiTum↑, 2,   CardioT↑, 1,   chemoPv⇅, 1,   fatigue↓, 1,   hepatoP↑, 3,   neuroP↑, 1,   OS↑, 6,   QoL↑, 2,   toxicity↓, 2,   toxicity↝, 2,   TumVol↓, 4,   TumW↓, 2,   Weight↑, 3,  
Total Targets: 189

Pathway results for Effect on Normal Cells:


Redox & Oxidative Stress ⓘ

antiOx↓, 1,   antiOx↑, 2,   Bil↓, 1,   Catalase↑, 4,   GPx↑, 2,   GSR↑, 2,   GSTs↑, 1,   H2O2↓, 1,   HDL↓, 1,   HDL↑, 1,   Iron↓, 1,   lipid-P↓, 2,   MDA↓, 2,   NRF2↑, 2,   ROS↓, 9,   ROS∅, 1,   SOD↑, 4,  

Mitochondria & Bioenergetics ⓘ

Insulin↑, 1,   MMP↑, 1,  

Core Metabolism/Glycolysis ⓘ

ACLY∅, 1,   ALAT↓, 1,   glucose↓, 1,   HMG-CoA↓, 1,   LDH↓, 1,  

Cell Death ⓘ

Akt↓, 1,   Casp3↓, 1,   Casp9↓, 1,   Cyt‑c↓, 1,   Fas↓, 1,   MAPK↓, 2,  

Transcription & Epigenetics ⓘ

Ach↑, 1,   other↑, 3,   other↝, 2,  

Protein Folding & ER Stress ⓘ

ER Stress↓, 1,   HSP70/HSPA5↑, 1,   HSPs↑, 1,  

DNA Damage & Repair ⓘ

DNAdam↓, 1,   DNArepair↑, 1,  

Proliferation, Differentiation & Cell State ⓘ

GSK‐3β↓, 1,   PI3K↓, 1,   PTEN↑, 1,   TRPM7↓, 1,   Wnt↑, 1,  

Migration ⓘ

AntiAg↑, 1,   APP↓, 1,   MMP9↓, 1,   β-catenin/ZEB1↑, 1,  

Angiogenesis & Vasculature ⓘ

VEGF↑, 1,  

Barriers & Transport ⓘ

BBB↑, 1,  

Immune & Inflammatory Signaling ⓘ

COX1↓, 1,   COX2↓, 2,   CRP↓, 1,   CXCR4↓, 1,   IL17↓, 1,   IL18↓, 1,   IL1β↓, 1,   IL6↓, 1,   Imm↑, 1,   Inflam↓, 3,   NF-kB↓, 1,   PGE2↓, 1,   TNF-α↓, 1,  

Synaptic & Neurotransmission ⓘ

AChE↓, 1,   BDNF↑, 1,   tau↓, 1,  

Protein Aggregation ⓘ

Aβ↓, 4,  

Drug Metabolism & Resistance ⓘ

BioAv↓, 2,   BioAv↑, 4,   BioAv↝, 1,   Dose↑, 3,   Dose⇅, 1,   Dose↝, 14,   eff↑, 3,   eff↝, 1,   Half-Life↝, 1,   P450↓, 1,  

Clinical Biomarkers ⓘ

ALAT↓, 1,   ALP↓, 1,   AST↓, 1,   Bil↓, 1,   BP↓, 1,   CRP↓, 1,   GutMicro↑, 1,   IL6↓, 1,   LDH↓, 1,  

Functional Outcomes ⓘ

AntiDiabetic↑, 3,   cardioP↑, 1,   cognitive↑, 5,   hepatoP↑, 1,   memory↑, 5,   motorD↑, 2,   neuroP↑, 6,   Obesity↓, 3,   OS↑, 1,   Pain↓, 1,   RenoP↑, 1,   Risk↓, 2,   toxicity↓, 4,   toxicity↝, 1,   toxicity∅, 2,   Wound Healing↑, 1,  

Infection & Microbiome ⓘ

Bacteria↓, 1,   CD8+↑, 1,  
Total Targets: 103

Scientific Paper Hit Count for: Dose, Dosage
31 Selenium NanoParticles
30 Magnetic Fields
21 Curcumin
19 Resveratrol
18 Silver-NanoParticles
17 Vitamin C (Ascorbic Acid)
16 Selenium
16 Selenite (Sodium)
15 Radiotherapy/Radiation
14 Apigenin (mainly Parsley)
14 Propolis -bee glue
14 Hydrogen Gas
12 Chemotherapy
12 Carvacrol
12 Chlorogenic acid
11 EGCG (Epigallocatechin Gallate)
10 Sulforaphane (mainly Broccoli)
9 Baicalein
8 Auranofin
8 Lycopene
8 Magnetic Field Rotating
7 3-bromopyruvate
7 Capsaicin
7 chitosan
7 Citric Acid
7 Ellagic acid
7 Exercise
7 Silymarin (Milk Thistle) silibinin
7 Whole Body Vibration
6 5-Hydroxytryptophan
6 Astaxanthin
6 Melatonin
6 nicotinamide adenine dinucleotide
6 Copper and Cu NanoParticles
6 Dichloroacetate
6 Electrical Pulses
6 SonoDynamic Therapy UltraSound
6 Phenethyl isothiocyanate
5 Alpha-Lipoic-Acid
5 Allicin (mainly Garlic)
5 Acetyl-l-carnitine
5 Metformin
5 Aspirin -acetylsalicylic acid
5 Boron
5 Spermidine
5 Hydroxycinnamic-acid
5 diet FMD Fasting Mimicking Diet
5 Bicarbonate(Sodium)
5 Phenylbutyrate
5 Rosmarinic acid
5 Vitamin D3
5 VitK3,menadione
4 cetuximab
4 Ashwagandha(Withaferin A)
4 Berberine
4 Boswellia (frankincense)
4 Butyrate
4 Caffeic acid
4 Celastrol
4 immunotherapy
4 Coenzyme Q10
4 Oxygen, Hyperbaric
4 Shilajit/Fulvic Acid
4 Propyl gallate
4 Thymoquinone
3 Astragalus
3 Artemisinin
3 Aloe anthraquinones
3 beta-glucans
3 Bromelain
3 borneol
3 Cat’s Claw
3 Calorie Restriction Mimetics
3 HydroxyCitric Acid
3 Disulfiram
3 Fisetin
3 Honokiol
3 metronomic chemo
3 Methylsulfonylmethane
3 Piperlongumine
3 Shikonin
3 Aflavin-3,3′-digallate
3 Urolithin
3 Vitamin B1/Thiamine
3 Vitamin E
3 Vitamin K2
2 Glucose
2 almonertinib
2 Bevacizumab (brand Avastin)
2 Anti-oxidants
2 Ascorbyl Palmitate
2 Paclitaxel
2 Atorvastatin
2 Betulinic acid
2 beta-carotene(VitA)
2 Bicalutamide
2 Calcium
2 Sorafenib (brand name Nexavar)
2 Celecoxib
2 Chrysin
2 doxorubicin
2 Garcinol
2 diet Plant based
2 diet Short Term Fasting
2 Folic Acid, Vit B9
2 Gambogic Acid
2 Potassium
2 Luteolin
2 capecitabine
2 Iron
2 Niclosamide (Niclocide)
2 probiotics
2 Bifidobacterium
2 Silicic Acid
2 Vitamin B5,Pantothenic Acid
1 5-Aminolevulinic acid
1 Photodynamic Therapy
1 Cisplatin
1 Aromatherapy
1 Baicalin
1 Biochanin A
1 bempedoic acid
1 Bufalin/Huachansu
1 Brucea javanica
1 Bacopa monnieri
1 Bortezomib
1 brusatol
1 Bruteridin(bergamot juice)
1 urea
1 Catechins
1 Cannabidiol
1 Chlorophyllin
1 Choline
1 Camptothecin
1 Crocetin
1 CUSP9
1 diet Ketogenic
1 Docetaxel
1 Zinc
1 Emodin
1 Ferulic acid
1 Fenbendazole
1 Gallic acid
1 Ginkgo biloba
1 Ginger/6-Shogaol/Gingerol
1 Huperzine A/Huperzia serrata
1 itraconazole
1 Juglone
1 MCToil
1 nivolumab
1 magnetic nanoparticles
1 Mushroom Lion’s Mane
1 Naringin
1 Nimbolide
1 Oleuropein
1 Hyperthermia
1 Phosphatidylserine
1 Pterostilbene
1 Quercetin
1 Ramucirumab (CYRAMZA)
1 Radio Frequency
1 salinomycin
1 Sulfasalazine
1 irinotecan
1 Taurine
1 Thymol-Thymus vulgaris
1 Ursolic acid
1 Vitamin B6,pyridoxine
1 Vitamin B12
1 Transarterial Chemoembolization
1 Xylitol
Query results interpretion may depend on "conditions" listed in the research papers.
Such Conditions may include : 
  -low or high Dose
  -format for product, such as nano of lipid formations
  -different cell line effects
  -synergies with other products 
  -if effect was for normal or cancerous cells

Filter Conditions: Pro/AntiFlg:%  IllCat:%  CanType:%  Cells:%  prod#:%  Target#:1114  State#:%  Dir#:%
  wNotes=0  sortOrder:rid,rpid

 

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