BBB Cancer Research Results

BBB, Blood-Brain Barrier Permeability: Click to Expand ⟱
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Blood-Brain Barrier(BBB) is a term often used regarding if a product has the ability to cross the BBB.
Scientific Papers found: Click to Expand⟱
2916- LT,    Antioxidative and Anticancer Potential of Luteolin: A Comprehensive Approach Against Wide Range of Human Malignancies
- Review, Var, NA - Review, AD, NA - Review, Park, NA
proCasp9↓, CDC2↓, CycB/CCNB1↓, Casp9↑, Casp3↑, Cyt‑c↑, cycA1/CCNA1↑, CDK2↓, APAF1↑, TumCCA↑, P53↑, BAX↑, VEGF↓, Bcl-2↓, Apoptosis↑, p‑Akt↓, p‑EGFR↓, p‑ERK↓, p‑STAT3↓, cardioP↑, Catalase↓, SOD↓, *BioAv↓, *antiOx↑, *ROS↓, *NO↓, *GSTs↑, *GSR↑, *SOD↑, *Catalase↑, *lipid-P↓, PI3K↓, Akt↓, CDK2↓, BNIP3↑, hTERT/TERT↓, DR5↑, Beclin-1/ATG6↑, TNF-α↓, NF-kB↓, IL1↓, IL6↓, EMT↓, FAK↓, E-cadherin↑, MDM2↓, NOTCH↓, MAPK↑, Vim↓, N-cadherin↓, Snail↓, MMP2↓, Twist↓, MMP9↓, ROS↑, MMP↓, *AChE↓, *MMP↑, *Aβ↓, *neuroP↑, Trx1↑, ROS↓, *NRF2↑, NRF2↓, *BBB↑, ChemoSen↑, GutMicro↑, *antiAll↑, *Mucositis↓, *TregCell↑, *Beclin-1/ATG6↓, *PI3K↑, *Akt↑, *mTOR↑,
4295- LT,    Luteolin Reduces Alzheimer’s Disease Pathologies Induced by Traumatic Brain Injury
- in-vivo, AD, NA
*Aβ↓, *GSK‐3β↓, *p‑tau↓, *BBB↑,
4292- LT,    Luteolin for neurodegenerative diseases: a review
- Review, AD, NA - Review, Park, NA - Review, MS, NA - Review, Stroke, NA
*Inflam↓, *antiOx↑, *neuroP↑, *BioAv↝, *BBB↑, *TNF-α↓, *IL1β↓, *IL6↓, *IL8↓, *IL33↓, *NF-kB↓, *BACE/β-secretase↓, *ROS↓, *SOD↑, *HO-1↑, *NRF2↑, *Casp3↓, *Casp9↑, *Bax:Bcl2↓, *UPR↑, *GRP78/BiP↑, *Aβ↓, *GSK‐3β↓, *tau↓, *CREB↑, *ATP↑, *cognitive↑, *BloodF↑, *BDNF↑, *TrkB↑, *memory↑, *PPARγ↑, *Synergy↑,
3528- Lyco,    The Importance of Antioxidant Activity for the Health-Promoting Effect of Lycopene
- Review, Nor, NA - Review, AD, NA - Review, Park, NA
*antiOx↑, *ROS↓, *BioAv↝, *Half-Life↑, *BioAv↓, *BioAv↑, *cardioP↑, *neuroP↑, *H2O2↓, *VitC↑, *VitE↑, *GPx↑, *GSH↑, *MPO↓, *GSTs↓, *SOD↑, *NF-kB↓, *IL1β↓, *IL6↓, *IL10↑, *MAPK↓, *Akt↓, *COX2/PTGS2↓, *TNF-α↓, *TGF-β1↑, *NO↓, *GSR↑, *NRF2↑, *HO-1↑, *TAC↑, *Inflam↓, *BBB↑, *neuroP↑, *memory↑,
8411- Lyco,    Lycopene destabilizes preformed Aβ fibrils: Mechanistic insights from all-atom molecular dynamics simulation
- Study, AD, NA
*antiOx↑, *BBB↑, *Aβ↓,
4230- Lyco,    Supplementation of lycopene attenuates oxidative stress induced neuroinflammation and cognitive impairment via Nrf2/NF-κB transcriptional pathway
- in-vivo, AD, NA
*BDNF↑, *antiOx↑, *Inflam↓, *HO-1↑, *NQO1↑, *IL1β↓, *TNF-α↓, *ROS↓, *NRF2↑, *cognitive↑, *BBB↑,
4778- Lyco,    Lycopene exerts cytotoxic effects by mitochondrial reactive oxygen species–induced apoptosis in glioblastoma multiforme
- in-vitro, GBM, GBM8401
BBB↑, Apoptosis↑, TumCP↑, P53↑, CycB/CCNB1↓, cycD1/CCND1↓, TumCCA↓, mt-ROS↑, TumCG↓,
8734- M-Blu,    From Mitochondrial Function to Neuroprotection – An Emerging Role for Methylene Blue
- Review, AD, NA
*ETC↑, *compIV↑, *ROS↓, *NeuroI↓, *neuroP↑, *Stroke↓, *cognitive↑, *BBB↑, *BloodF↑, *NOS2↓, *lipid-P↓, *Inflam↓, *Synergy↑, *OCR↑, *compIV↑, *ATP↑, *Casp↓, *MMP↑, *tau↓,
8728- M-Blu,    Neurometabolic mechanisms for memory enhancement and neuroprotection of methylene blue
- Review, AD, NA
*Dose↝, *antiOx↑, *mitResp↑, *neuroP↑, *memory↑, *CellMemb↑, *BBB↑, *other↝, *compV↑, *OCR↑, *ROS↓, *Sepsis↓, *NO↓, *RNS↓, *memory↑, *tau↓, *CX43/GJA1↑, *THBD↑, *CARTPT↑,
8731- M-Blu,    Exploring Methylene Blue and Its Derivatives in Alzheimer's Treatment: A Comprehensive Review of Randomized Control Trials
- Review, AD, NA
*BBB↑, *cognitive↑, *Aβ↓, *memory↑, *antiOx↑, *ROS↓, *Inflam↓, *BrainVol↑, *p‑tau↓, *cellSen↝, *memory↑, *neuroP↑,
8733- M-Blu,    Mitochondria as a target for neuroprotection: role of methylene blue and photobiomodulation
- Review, AD, NA - Review, Stroke, NA
*ETC↑, *ROS↓, *Inflam↓, *memfluid↑, *BloodF↑, *BBB↑, *OCR↑, *ATP↑, *BioAv↑, *Aβ↓, *compIV↑, *Stroke↓, *compI↑, *compII↑, *compIII↑, *GlucoseCon↑, *neuroG↑,
2544- M-Blu,    Methylene blue and its importance in medicine
- Review, Nor, NA
*ROS↓, *antiOx↑, *BBB↑, *neuroP↑, *GSR↓, *tau↓,
2540- M-Blu,    Alternative mitochondrial electron transfer for the treatment of neurodegenerative diseases and cancers: Methylene blue connects the dots
- Review, Var, NA - Review, AD, NA
*OCR↑, *Glycolysis↓, *GlucoseCon↑, neuroP↑, Warburg↓, mt-OXPHOS↑, TumCCA↑, TumCP↓, ROS⇅, *cognitive↑, *mTOR↓, *mt-antiOx↑, *memory↑, *BBB↑, *eff↝, *ECAR↓, eff↑, lactateProd↓, NADPH↓, OXPHOS↑, AMPK↑, selectivity↑,
4519- MAG,    Magnolol: A Neolignan from the Magnolia Family for the Prevention and Treatment of Cancer
- Review, Var, NA
*antiOx↑, *Inflam↓, *Bacteria↓, *AntiAg↑, *BBB↑, *BioAv↓, BAD↑, Casp3↑, Casp6↑, Casp9↑, JNK↑, Bcl-xL↓, PTEN↑, Akt↓, NF-kB↓, MMP7↓, MMP9↓, uPA↓, Hif1a↓, VEGF↓, FOXO3↓, Ca+2↑, TumCCA↑, ROS↑, Cyt‑c↑,
8552- Matr,    Matrine exerts its neuroprotective effects by modulating multiple neuronal pathways
- Review, AD, NA
*BBB↑, *neuroP↑, *HMGB1↓, *NF-kB↓, *MyD88↓, *TLR4↓, *TRAF6↓, *Cyt‑c↓, *MDA↓, *Beclin-1/ATG6↑, *GPx↑, *IL23↓, *IL17↓, *NRF2↑, *HO-1↑, *SOD↑, *GSH↑, *Stroke↓, *BACE/β-secretase↓, *Aβ↓, *BDNF↑, *AChE↓, *BChE↓, *ROS↓, *memory↑, *NP/CIPN↓,
8546- Matr,    Matrine Attenuates Neurological Deficits and Neuroinflammation by Inhibiting the HMGB1/RAGE Axis and Ferroptosis in Intracerebral Hemorrhage Mice
- in-vivo, Stroke, NA
*Dose?, *Stroke↓, *BBB↝, *TJ↑, *ZO-1↑, *OCLN↑, *CLDN4↑, *HMGB1↓, *RAGE↓, *JNK↓, *p38↓, *ERK↓, *NF-kB↓, *IL1β↓, *IL6↓, *TNF-α↓, *BAX↓, *Bcl-2↑, *Apoptosis↓, *Iron↓, *ACSL4↓, *GPx4↑, *Ferroptosis↓, *neuroP↑, *Inflam↓, *antiOx↑,
7824- MBS,  IVT,  VT,    Neuroprotective Potential of Mung Bean (Vigna radiata L.) Polyphenols in Alzheimer's Disease: A Review
- Review, AD, NA - Review, Stroke, NA - Review, Park, NA
*neuroP↑, *Aβ↓, *p‑tau↓, *ROS↓, *Inflam↓, *AChE↓, *BBB↑, *memory↑, *hepatoP↑, *Imm↑, *hyperG↓, *AntiCan↑, *eff↑, *Stroke↓, *BACE/β-secretase↓, *PI3K↓, *Akt↓, *mTOR↓, *Dose↓,
8648- MBZ,    Mebendazole as a Candidate for Drug Repurposing in Oncology: An Extensive Review of Current Literature
- Review, Var, NA
angioG↓, MMPs↓, MDR1↓, TubPol↓, RadioS?, ChemoSen?, TumCG↓, TumMeta?, OS↑, BioAv↓, BioAv↑, BBB↑, mitA↑, HH↓, Shh↓, Synergy↑, Gli1↓, PTCH2↓, XIAP↓, cl‑PARP↑, Casp3↑, BRAF↓, MEK↓, SYN1↑, Cyt‑c↑, TumVol↓, VEGFR2/KDR/Flk1↓, VEGF↓, VCAM-1↓, DYRK1B↓, QoL↑, Dose↝,
3901- MCT,    Potential of Capric Acid in Neurological Disorders: An Overview
- Review, AD, NA
*BBB↑, *cognitive↑,
3737- MF,    The Effect of Time-Dependence of 10 Hz Electromagnetic Field on Spatial Learning and Memory in Rats
- in-vivo, AD, NA
*memory↑, *BDNF↑, *BBB↑,
9087- MGF,    Mangiferin in human disease: Multifaceted mechanisms and applications (Review)
- Review, Var, NA
TumCP↓, TumCI↓, angioG↓, *BioAv↓, *neuroP↑, *Inflam↓, *AntiCan↑, *ROS↓, *BioAv↑, *BioAv↝, *Half-Life↝, *BBB↓, CDK1↑, CycB/CCNB1↑, Bcl-2↓, BAX↑, Casp3↑, Casp7↑, Casp8↑, Casp9↑, cl‑PARP↑, PI3K↓, Akt↓, mTOR↓, MMP↓, MOMP↑, Apoptosis↑, lipid-P↑, TCA↓, NRF2↑, NQO1↑, ROS↓, RadioS↑,
1777- MLT,    Melatonin as an antioxidant: under promises but over delivers
- Review, Var, NA
*ROS↓, *Fenton↓, *antiOx↑, *toxicity∅, *GPx↑, *GSR↑, *GSH↑, *NO↓, *Iron↓, *Copper↓, *IL1β↓, *iNOS↓, *Casp3↓, *BBB↑, *RenoP↑, chemoP↑, *Ca+2↝, eff↑, *PKCδ?, ChemoSen↑, eff↑, Akt↓, DR5↑, selectivity↑, ROS↑, Synergy↑,
8657- MLT,    Melatonin in Alzheimer's Disease: Literature Review and Therapeutic Trials
- Review, AD, NA
*toxicity↓, *Sleep↑, *antiOx↑, *AntiMyl↑, *p‑tau↓, *Aβ↓, *TC↓, *neuroP↑, *ROS↓, *BBB↑, *Learn↑, *memory↑, *Synergy↑, *Dose↝,
3839- MO,    Nutritional Value of Moringa oleifera Lam. Leaf Powder Extracts and Their Neuroprotective Effects via Antioxidative and Mitochondrial Regulation
- in-vitro, AD, NA
*eff↑, *ROS↓, *lipid-P↓, *GSH↑, *antiOx↑, *Ca+2↓, *MMP↑, *neuroP↑, *BBB↑, *Catalase↑, *SOD↑, GPx↑,
3846- MSM,    Accumulation of methylsulfonylmethane in the human brain: identification by multinuclear magnetic resonance spectroscopy
- Human, Nor, NA
*Dose↝, *BBB↑, *eff↓,
8950- mushLions,    Absolute Bioavailability, Tissue Distribution, and Excretion of Erinacine S in Hericium erinaceus Mycelia
- in-vivo, AD, NA
*Aβ↓, *neuroG↑, *Dose↝, *BioAv↝, *BBB↑, *Half-Life↝,
8959- mushLions,  BM,  L-THE,    Phytochemical and Fungal Bioactive Compounds in the “Brain Health Triad”: A Narrative Review on Neurostimulating, Neurotrophic, and Neuroprotective Synergy
- Review, AD, NA
*Synergy↑, *neuroP↑, *INF-γ↑, *BDNF↑, *Synergy↑, *Synergy↑, *BBB↑, *Ki-67↑, *p‑CREB↑, *tau↓, *GSK‐3β↓, *Wnt↑, *β-catenin/ZEB1↑, *memory↑, *Sleep↑, *p‑NF-kB↓, *ROS↓, *Stress↓,
8964- mushLions,    Lion’s Mane Mushroom (Hericium erinaceus): A Neuroprotective Fungus with Antioxidant, Anti-Inflammatory, and Antimicrobial Potential—A Narrative Review
- Review, Nor, NA - Review, AD, NA
*Ingr↝, *ROS↓, *antiOx↑, *AntiBio↑, *NGF↑, *neuroG↑, *memory↑, *neuroP↑, *NF-kB↓, *COX2/PTGS2↓, *NeuroI↓, *cognitive↑, *NRF2↑, *SOD↑, *GPx↑, *GutMicro↑, *BBB↑, *BioAv↝,
3814- mushLions,    Lion's Mane (Hericium erinaceus) Exerts Anxiolytic Effects in the rTg4510 Tau Mouse Model
- in-vitro, AD, NA
*neuroP↑, *cognitive↑, *cognitive∅, *BBB↑, *NGF↑, *BDNF↑, *NO↓, *memory↑, *Aβ↓,
3811- mushLions,    Hericium erinaceus (Bull.) Pers. Ethanolic Extract with Antioxidant Properties on Scopolamine-Induced Memory Deficits in a Zebrafish Model of Cognitive Impairment
- in-vitro, AD, NA
*memory↑, *BBB↑, *GSH↑, *AChE↓, *MDA↓,
2484- mushLions,    Neurotrophic and Neuroprotective Effects of Hericium erinaceus
- Review, Stroke, NA - Review, AD, NA - Review, Park, NA
*eff↑, *BBB↑, *Dose↝, *neuroP↑, *cognitive↑, *toxicity∅,
7828- Myr,  MBS,    Neuroprotective Potential of Mung Bean (Vigna radiata L.) Polyphenols in Alzheimer's Disease: A Review
- Review, AD, NA
*BBB↑, *neuroP↑, *cognitive↑, *Aβ↓, *ADAM10↑, *BACE/β-secretase↝, *IronCh↑, *Iron↓, *AChE↓, *ROS↓,
116- Myrrh,    The Role of Myrrh Metabolites in Cancer, Inflammation, and Wound Healing: Prospects for a Multi-Targeted Drug Therapy
- in-vitro, AML, HL-60 - in-vitro, AML, K562 - in-vitro, BC, KAIMRC1
ROS↑, M1↑, M2 MC↑, Apoptosis?, BBB↝,
4036- NAD,  VitB3,    NAD+ supplementation normalizes key Alzheimer’s features and DNA damage responses in a new AD mouse model with introduced DNA repair deficiency
- in-vivo, AD, NA
*Inflam↓, *p‑tau↓, *DNAdam↓, *memory↑, *motorD↑, *cognitive↑, *BBB↑, IL1β↓, *TNF-α↓, *MCP1/CCL2↓, *RANTES↓, *ROS↓, *SIRT3↑, *SIRT6↑,
6487- Nimb,    Anticancer properties of nimbolide and pharmacokinetic considerations to accelerate its development
- Review, Var, NA
TumCP↓, Apoptosis↓, TumMeta↑, angioG↓, *antiOx↑, *eff↑, Apoptosis↑, MOMP↑, CDK1↓, TumCCA↑, MAPK↓, JAK2↓, STAT3↓, PI3K↓, Akt↓, TumCP↓, *NRF2↑, NF-kB↓, GSK‐3β↑, Wnt↓, β-catenin/ZEB1↓, chemoPv↑, Bcl-xL↓, Bcl-2↓, survivin↓, Cyt‑c↑, BAX↑, BID↑, cl‑Casp↑, P53↑, DR5↑, DR4↑, ROS↑, lipid-P↑, MDA↑, MMP2↓, MMP9↓, uPA↓, ICAM-1↓, CXCR4↓, CXCR2↓, angioG↓, BBB↑,
7532- Olive Oil,  HT,  OLE,    Impact of Olive Oil Fatty Acids and Bioactive Compounds on Cognitive Function in Adults: A Systematic Review
- Review, AD, NA
*cognitive↑, *memory↑, *BBB↝, *neuroP↑,
7831- PCA,  MBS,    Neuroprotective Potential of Mung Bean (Vigna radiata L.) Polyphenols in Alzheimer's Disease: A Review
- Review, AD, NA
*BBB↑, *neuroP↑, *Aβ↓, *p‑tau↓, *autophagy↓, *GSK‐3β↓, *NeuroI↓, *iNOS↓, *COX2/PTGS2↓, *BDNF↑, *MEF2D↑, *cognitive↑, *memory↑,
9114- PRO,    Repurposing Drugs in Oncology (ReDO)—Propranolol as an anti-cancer agent
- Review, Var, NA
ADRB2↓, TumCP↓, TumCI↓, Imm↑, angioG↓, BioAv↑, Half-Life↝, BBB↑, BioAv↝, MMP2↓, MMP9↓, VEGF↓,
3923- PTS,    Pterostilbene Supplement Benefits: Longevity Miracle or Hoax
- Review, AD, NA
*BioAv↑, *Half-Life↑, *BBB↑, *BP↓, *cognitive↑,
3922- PTS,    Pterostilbene attenuates amyloid-β induced neurotoxicity with regulating PDE4A-CREB-BDNF pathway
- in-vivo, AD, NA
*BioAv↑, *BBB↑, *memory↑, *p‑CREB↑, *BDNF↑, *PSD95↑, *neuroP↑,
5032- PTS,    Pterostilbene Decreases the Antioxidant Defenses of Aggressive Cancer Cells In Vivo: A Physiological Glucocorticoids- and Nrf2-Dependent Mechanism
- in-vivo, Melanoma, NA
TumCG↓, NRF2↓, GR↓, BBB↑, ACTH↓, eff↑,
5034- PTS,    Pterostilbene in Cancer Therapy
- Review, Var, NA
BioAv↓, Half-Life↓, iNOS↓, Apoptosis↑, STAT3↓, Akt↓, mTOR↓, NF-kB↓, NRF2↓, ChemoSen↑, BBB↑,
4693- PTS,    Pterostilbene in the treatment of inflammatory and oncological diseases
- Review, Var, NA
BioAv↑, *Inflam↓, *antiOx↑, AntiTum↑, BBB↑, Half-Life↝, *ROS↓, *NRF2↑, *NQO1↑, *HO-1↑, PTEN↑, miR-19b↓, TumCCA↑, ER Stress↑, PERK↑, ATF4↑, CHOP/DDIT3↑, Ca+2↝, EMT↓, NF-kB↓, Twist↓, Vim↓, E-cadherin↑, ChemoSen↑, toxicity∅, toxicity↝,
3336- QC,    Neuroprotective Effects of Quercetin in Alzheimer’s Disease
- Review, AD, NA
*neuroP↑, *lipid-P↓, *antiOx↑, *Aβ↓, *Inflam↓, *BBB↝, *NF-kB↓, *iNOS↓, *memory↑, *cognitive↑, *AChE↓, *MMP↑, *ROS↓, *ATP↑, *AMPK↑, *NADPH↓, *p‑tau↓,
3339- QC,    Quercetin suppresses ROS production and migration by specifically targeting Rac1 activation in gliomas
- in-vitro, GBM, C6 - in-vitro, GBM, IMR32
BBB↑, tumCV↓, TumCMig↓, Rac1↓, p66Shc↓, ROS↓,
3363- QC,    The Protective Effect of Quercetin on Endothelial Cells Injured by Hypoxia and Reoxygenation
- in-vitro, Nor, HBMECs
*Apoptosis↓, *angioG↑, *NRF2↑, *Keap1↓, *ATF6↓, *GRP78/BiP↓, *CLDN5↑, *ZO-1↑, *MMP↑, *BBB↑, *ROS↓, *ER Stress↓,
3602- QC,    The flavonoid quercetin ameliorates Alzheimer's disease pathology and protects cognitive and emotional function in aged triple transgenic Alzheimer's disease model mice
- in-vivo, AD, NA
*BACE/β-secretase↓, *cognitive↑, *ROS↓, *lipid-P↓, *iNOS↓, *COX2/PTGS2↓, *BBB↑, *neuroP↑, *other↓, *memory↑,
6054- RES,  SeNPs,    Oral Administration of Resveratrol-Selenium-Peptide Nanocomposites Alleviates Alzheimer's Disease-like Pathogenesis by Inhibiting Aβ Aggregation and Regulating Gut Microbiota
- in-vivo, AD, NA
*Dose↝, *cognitive↑, *Aβ↓, *ROS↓, *TAC↑, *GutMicro↑, *BBB↑,
2566- RES,    A comprehensive review on the neuroprotective potential of resveratrol in ischemic stroke
- Review, Stroke, NA
*neuroP↑, *NRF2↑, *SIRT1↑, *PGC-1α↑, *FOXO↑, *HO-1↑, *NQO1↑, *ROS↓, *BP↓, *BioAv↓, *Half-Life↝, *AMPK↑, *GSK‐3β↓, *eff↑, *AntiAg↑, *BBB↓, *Inflam↓, *MPO↓, *TLR4↓, *NF-kB↓, *p65↓, *MMP9↓, *TNF-α↓, *IL1β↓, *PPARγ↑, *MMP↑, *ATP↑, *Cyt‑c∅, *mt-lipid-P↓, *H2O2↓, *HSP70/HSPA5↝, *Mets↝, *eff↑, *eff↑, *motorD↑, *MDA↓, *NADH:NAD↑, eff↑, eff↑,
3100- RES,    Neuroprotective effects of resveratrol in Alzheimer disease pathology
- Review, AD, NA
*neuroP↑, *BioAv↓, *Half-Life↓, *BioAv↑, *BBB↑, *NRF2↑, *BioAv↓, *BioAv↑, *SIRT1↑, *cognitive↑, *lipid-P↓, *HO-1↑, *SOD↑, *GSH↑, *GPx↑, *G6PD↑, *PPARγ↑, *AMPK↑, *Aβ↓,

Showing Research Papers: 151 to 200 of 238
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* indicates research on normal cells as opposed to diseased cells
Total Research Paper Matches: 238

Pathway results for Effect on Cancer / Diseased Cells:


Redox & Oxidative Stress(tgid=1) ⓘ

antiOx↑, 3,   antiOx⇅, 1,   Catalase↓, 2,   Catalase↑, 1,   GPx↑, 1,   GPx4↓, 1,   GSH↓, 3,   GSTs↑, 1,   HO-1↓, 1,   HO-1↑, 1,   Iron↑, 1,   Iron↝, 1,   lipid-P↑, 6,   MDA↓, 1,   MDA↑, 4,   NADH↓, 1,   NQO1↑, 1,   NRF2↓, 4,   NRF2↑, 3,   p66Shc↓, 1,   ROS↓, 5,   ROS↑, 31,   ROS⇅, 2,   mt-ROS↑, 3,   SOD↓, 2,   SOD↑, 1,   SOD2↓, 1,   Trx1↑, 1,   TrxR↓, 1,  

Metal & Cofactor Biology(tgid=2) ⓘ

IronCh↑, 1,  

Mitochondria & Bioenergetics(tgid=3) ⓘ

CDC2↓, 1,   mitResp↓, 1,   mtDam↑, 3,   OCR↓, 2,   OCR↑, 1,   OXPHOS↑, 1,   mt-OXPHOS↑, 1,   PINK1↑, 1,   SIRT3↑, 1,  

Core Metabolism/Glycolysis(tgid=4) ⓘ

5LO↓, 2,   AMPK↑, 2,   ATP↓, 1,   mt-ATP↓, 1,   ECAR↓, 1,   FASN↓, 1,   GlutMet↓, 1,   Glycolysis↓, 1,   GSK‐3β↑, 3,   lactateProd↓, 1,   NADPH↓, 1,   PDK1 / PDPK1↓, 1,   PDK3↑, 1,   SIRT1↓, 1,   SIRT1↑, 1,   TCA↓, 1,   Warburg↓, 1,  

Cell Death(tgid=5) ⓘ

APAF1↑, 1,   Apoptosis?, 1,   Apoptosis↓, 2,   Apoptosis↑, 22,   mt-Apoptosis↑, 1,   BAD↓, 1,   BAD↑, 1,   Bak↓, 1,   Bak↑, 2,   BAX↑, 10,   Bax:Bcl2↑, 1,   Bcl-2↓, 11,   Bcl-xL↓, 4,   BID↓, 1,   BID↑, 2,   BNIP3↑, 1,   Casp↑, 4,   cl‑Casp↑, 1,   Casp12↑, 1,   Casp3↓, 1,   Casp3↑, 17,   cl‑Casp3↑, 2,   proCasp3↓, 1,   Casp6↑, 1,   Casp7↑, 1,   Casp8↑, 7,   Casp9↑, 13,   cl‑Casp9↑, 1,   proCasp9↓, 1,   cFLIP↓, 2,   Cyt‑c↑, 17,   DR5↑, 4,   Fas↑, 2,   Ferroptosis↑, 2,   GranB/GZMB↝, 1,   ICD↑, 1,   iNOS↓, 1,   Mcl-1↑, 1,   MDM2↓, 1,   MOMP↑, 2,   p38↑, 2,   p‑p38↓, 1,   Perforin↝, 1,   survivin↓, 3,   TumCD↑, 1,   XIAP↓, 2,   XIAP↑, 1,  

Kinase & Signal Transduction(tgid=6) ⓘ

Akt↓, 18,   p‑Akt↓, 5,   BRAF↓, 1,   cSrc↓, 1,   DYRK1B↓, 1,   EF-1α↓, 1,   EGFR↓, 3,   EGFR↑, 1,   p‑EGFR↓, 1,   ERK↓, 3,   p‑ERK↓, 2,   FOXD3↑, 1,   HER2/EBBR2↓, 1,   HGF/c-Met↓, 1,   IKKα↓, 1,   JAK1↓, 1,   JAK2↓, 3,   JNK↓, 1,   JNK↑, 2,   MAPK↓, 5,   MAPK↑, 1,   MEK↓, 1,   mTOR↓, 8,   p‑mTOR↓, 1,   PI3K↓, 12,   PTEN↑, 6,   c-Raf↓, 1,   RAS↓, 3,   Sp1/3/4↓, 1,   STAT3↓, 11,   p‑STAT3↓, 2,  

Transcription & Epigenetics(tgid=7) ⓘ

ATF4↑, 1,   cJun↑, 1,   cMyc↓, 3,   DNMTs↓, 2,   FOXM1↓, 1,   FOXO1↑, 1,   FOXO3↓, 1,   H3↓, 1,   H3↑, 1,   H4↑, 1,   HATs↑, 1,   HDAC↓, 2,   HDAC1↓, 1,   HIST1H3B?, 1,   miR-19b↓, 1,   Myc↓, 1,   OCT4↓, 1,   other↑, 2,   other↝, 3,   SOX2↓, 1,   SOX4↓, 1,   tumCV↓, 3,  

Protein Folding & ER Stress(tgid=8) ⓘ

CHOP/DDIT3↓, 1,   CHOP/DDIT3↑, 1,   cl‑CHOP/DDIT3↑, 1,   ER Stress↑, 5,   GRP78/BiP↑, 1,   HSP27↓, 1,   HSP90↓, 1,   PERK↑, 1,  

Autophagy & Lysosomes(tgid=9) ⓘ

ATG5↑, 2,   ATG7↑, 1,   Beclin-1/ATG6↑, 2,   CTSK↓, 1,   LC3II↑, 2,   MitoP↑, 1,   PARK2↑, 1,   TumAuto↑, 2,  

DNA Damage & Repair(tgid=10) ⓘ

DNAdam↑, 6,   DNArepair↓, 1,   hTERT/TERT↓, 2,   P53?, 1,   P53↑, 11,   P53↝, 1,   PARP↑, 2,   cl‑PARP↑, 9,   PARP1↑, 1,   PCNA↓, 2,   Telomerase↓, 3,   TOP1↓, 3,   TOP2↓, 1,   TOP2↑, 1,   γH2AX↑, 1,  

Cell Cycle & Senescence(tgid=11) ⓘ

CDK1↓, 1,   CDK1↑, 1,   CDK2↓, 5,   CDK4↓, 2,   CDK6↓, 1,   CHK1↓, 1,   cycA1/CCNA1↑, 1,   CycB/CCNB1↓, 4,   CycB/CCNB1↑, 2,   cycD1/CCND1↓, 3,   cycD1/CCND1↑, 1,   Ki-67↓, 2,   mitA↑, 1,   P21?, 1,   P21↑, 2,   p27/CDKN1B↑, 1,   p‑RB1↓, 1,   TubPol↓, 1,   TumCCA↓, 1,   TumCCA↑, 17,  

Proliferation, Differentiation & Cell State(tgid=12) ⓘ

BMP7/OP1↓, 1,   BMPs↑, 1,   CD133↓, 2,   cFos↓, 1,   CSCs↓, 2,   Diff↑, 1,   EIF4E↓, 1,   FGF↓, 1,   Gli1↓, 3,   HH↓, 3,   IGF-1↓, 1,   Ki-67↓, 2,   mTORC1↓, 2,   Nanog↓, 1,   Nestin↓, 1,   NOTCH↓, 1,   NOTCH1↓, 1,   NOTCH1↑, 1,   NOTCH3↓, 1,   PTCH2↓, 1,   Shh↓, 1,   TumCG↓, 13,   TumCP↓, 14,   TumCP↑, 2,   Wnt↓, 6,  

Migration(tgid=13) ⓘ

Ca+2↑, 2,   Ca+2↝, 1,   E-cadherin↑, 3,   EMT↓, 8,   FAK↓, 1,   p‑FAK↓, 2,   fascin↓, 1,   MMP2↓, 9,   MMP7↓, 1,   MMP9↓, 11,   MMP9↑, 2,   MMPs↓, 6,   N-cadherin↓, 2,   Rac1↓, 1,   Rho↓, 1,   Rho↑, 1,   ROCK1↓, 1,   ROCK1↑, 1,   Snail↓, 2,   TGF-β↓, 1,   TIMP1↓, 1,   TIMP1↑, 1,   TIMP2↑, 1,   TRIB3↑, 1,   TumCI↓, 7,   TumCMig↓, 7,   TumMeta?, 1,   TumMeta↓, 10,   TumMeta↑, 2,   Twist↓, 3,   uPA↓, 4,   Vim↓, 2,   Zeb1↓, 1,   β-catenin/ZEB1↓, 6,   β-catenin/ZEB1↑, 1,  

Angiogenesis & Vasculature(tgid=14) ⓘ

angioG↓, 16,   HIF-1↓, 1,   Hif1a↓, 10,   Hif1a↑, 1,   NO↝, 1,   VCAM-1↓, 1,   VEGF↓, 14,   VEGFR2/KDR/Flk1↓, 4,  

Barriers & Transport(tgid=15) ⓘ

BBB↓, 1,   BBB↑, 35,   BBB↝, 1,   BBB∅, 2,   EPR↑, 5,   EPR↝, 1,   GLUT1↓, 1,   MMP↓, 15,   MPT↑, 1,   TRPV1↑, 1,  

Immune & Inflammatory Signaling(tgid=16) ⓘ

CB2 / CNR2↑, 1,   COX2/PTGS2↓, 7,   CXCR2↓, 1,   CXCR4↓, 1,   DR4↑, 1,   ICAM-1↓, 2,   IL1↓, 1,   IL1↑, 1,   IL10↓, 1,   IL1β↓, 7,   IL2↑, 1,   IL6↓, 4,   IL8↓, 1,   IL8↑, 1,   Imm↑, 2,   Inflam↓, 7,   M1↑, 1,   M2 MC↑, 1,   NF-kB↓, 20,   NF-kB↑, 1,   NOD1↓, 1,   p65↓, 1,   PD-L1↓, 2,   PGE2↓, 3,   TNF-α↓, 7,  

Synaptic & Neurotransmission(tgid=18) ⓘ

SYN1↑, 1,  

Protein Aggregation(tgid=19) ⓘ

Aβ↓, 1,  

Hormonal & Nuclear Receptors(tgid=20) ⓘ

ACTH↓, 1,   ADRB2↓, 1,   AR↓, 1,   GR↓, 1,   PPARγ↑, 1,  

Drug Metabolism & Resistance(tgid=21) ⓘ

BioAv↓, 10,   BioAv↑, 11,   BioAv↝, 6,   BioEnh↑, 4,   ChemoSen?, 1,   ChemoSen↑, 25,   DDS↑, 1,   Dose↓, 1,   Dose↑, 1,   Dose↝, 9,   eff↓, 4,   eff↑, 21,   eff↝, 1,   Half-Life↓, 3,   Half-Life↑, 1,   Half-Life↝, 7,   MDR1↓, 3,   MRP1/ABCC1↓, 1,   P-gp/ABCB1↓, 6,   RadioS?, 1,   RadioS↑, 10,   selectivity↑, 8,   Synergy↑, 9,  

Clinical Biomarkers(tgid=22) ⓘ

AR↓, 1,   BRAF↓, 1,   CEA↓, 1,   EGFR↓, 3,   EGFR↑, 1,   p‑EGFR↓, 1,   FOXM1↓, 1,   HER2/EBBR2↓, 1,   hTERT/TERT↓, 2,   IL6↓, 4,   Myc↓, 1,   NOS2↑, 1,   PD-L1↓, 2,   TF-Ag↓, 1,   TRIB3↑, 1,  

Functional Outcomes(tgid=23) ⓘ

AntiCan↑, 7,   AntiTum↑, 4,   cardioP↑, 4,   chemoP↑, 7,   chemoPv↑, 3,   cognitive?, 1,   cognitive↑, 2,   hepatoP↑, 1,   memory↑, 1,   neuroP↓, 1,   neuroP↑, 3,   Obesity↓, 1,   OS↑, 7,   Pain↓, 1,   QoL↑, 2,   RenoP↑, 1,   Risk↑, 1,   toxicity↓, 5,   toxicity↑, 2,   toxicity↝, 3,   toxicity∅, 2,   TumVol↓, 3,   TumW↓, 1,  

Infection & Microbiome(tgid=24) ⓘ

AntiBio↓, 1,   GutMicro↑, 1,   GutMicro↝, 1,  
Total Targets: 381

Pathway results for Effect on Normal Cells:


NA, unassigned(tgid=0) ⓘ

NA↓, 1,   NA↝, 1,  

Redox & Oxidative Stress(tgid=1) ⓘ

4-HNE↓, 2,   antiOx↓, 3,   antiOx↑, 81,   mt-antiOx↑, 1,   ARE↑, 2,   Catalase↓, 1,   Catalase↑, 25,   Copper↓, 1,   CoQ10↑, 1,   Fenton↓, 2,   GPx↑, 18,   GPx4↑, 3,   GSH↑, 43,   GSR↓, 1,   GSR↑, 10,   GSTs↓, 3,   GSTs↑, 5,   H2O2↓, 2,   H2O2∅, 1,   HDL↑, 1,   HO-1↑, 25,   HO-2↓, 1,   hyperG↓, 1,   Iron↓, 4,   Keap1↓, 2,   Keap1↑, 2,   lipid-P↓, 31,   mt-lipid-P↓, 1,   MDA↓, 21,   MDA↑, 3,   MPO↓, 5,   NQO1↑, 7,   NQO1↝, 1,   NRF2↑, 50,   RNS↓, 4,   ROS?, 1,   ROS↓, 116,   ROS↑, 1,   SOD↓, 1,   SOD↑, 43,   mt-SOD↑, 1,   SOD1↑, 2,   SOD2↑, 1,   TAC↑, 4,   TBARS↓, 4,   Thiols↑, 1,   Trx↑, 1,   Trx1↑, 1,   TrxR↑, 1,   TrxR1↑, 1,   uricA↓, 1,   VitC↑, 3,   VitE↑, 3,  

Metal & Cofactor Biology(tgid=2) ⓘ

Ferritin↓, 1,   Ferritin↑, 1,   FPN↑, 1,   IronCh↑, 16,   Mets↝, 1,   TfR1/CD71↓, 2,   TfR1/CD71↑, 1,  

Mitochondria & Bioenergetics(tgid=3) ⓘ

compI↑, 1,   compII↑, 1,   compIII↑, 1,   compIV↑, 3,   compV↑, 1,   ETC↑, 3,   FIS1↓, 1,   mitResp↑, 1,   mtDam↓, 2,   OCR↑, 4,   PDH↑, 1,   PGC-1α↑, 5,   SIRT3↑, 4,  

Core Metabolism/Glycolysis(tgid=4) ⓘ

12LOX↓, 2,   5LO↓, 2,   ACC↑, 1,   Acetyl-CoA↑, 1,   ACSL4↓, 2,   adiP↑, 2,   ALAT↓, 5,   AMPK↑, 10,   p‑AMPK↑, 1,   ATP↑, 10,   cAMP↑, 2,   DHA↑, 1,   ECAR↓, 1,   FAO↓, 1,   G6PD↑, 1,   glucose↓, 1,   glucose↑, 1,   glucose↝, 2,   GlucoseCon↑, 5,   Glycolysis↓, 1,   GSK‐3β↓, 16,   GSK‐3β↑, 1,   p‑GSK‐3β↑, 3,   H2S↑, 1,   LDL↓, 5,   NADH:NAD↑, 1,   NADPH↓, 2,   NADPH↑, 2,   PDK1 / PDPK1↓, 1,   PDKs↓, 1,   SIRT1↓, 1,   SIRT1↑, 8,  

Cell Death(tgid=5) ⓘ

Apoptosis↓, 14,   ASC↓, 1,   BAX↓, 6,   BAX↑, 1,   Bax:Bcl2↓, 1,   Bcl-2↓, 3,   Bcl-2↑, 4,   Casp↓, 1,   Casp1↓, 1,   Casp3↓, 13,   Casp3↑, 1,   cl‑Casp3↓, 1,   Casp6↓, 1,   Casp9↓, 4,   Casp9↑, 1,   Cyt‑c↓, 2,   Cyt‑c↑, 1,   Cyt‑c∅, 1,   Ferroptosis↓, 5,   iNOS↓, 20,   necrosis↓, 1,   p38↓, 1,   p38↑, 1,   p‑p38↓, 2,  

Kinase & Signal Transduction(tgid=6) ⓘ

Akt↓, 4,   Akt↑, 10,   p‑Akt↑, 3,   AKT1↓, 1,   CREB↑, 3,   p‑CREB↑, 3,   ERK↓, 4,   ERK↑, 3,   p‑ERK↓, 1,   p‑ERK↑, 2,   IGF-1R↓, 1,   JAK↓, 1,   JNK↓, 3,   p‑JNK↓, 2,   MAPK↓, 9,   MAPK↑, 3,   mTOR↓, 5,   mTOR↑, 2,   p‑mTOR↓, 1,   P70S6K↓, 1,   PDGFR-BB↓, 1,   PI3K↓, 4,   PI3K↑, 7,   PKCδ?, 1,   PKCδ↑, 3,   PTEN↓, 3,   PTP1B↓, 1,   STAT3↓, 1,  

Transcription & Epigenetics(tgid=7) ⓘ

AntiThr↑, 1,   cJun↓, 1,   FOXO↑, 1,   FOXO3↑, 1,   H3↑, 1,   H4↑, 1,   HDAC1↓, 1,   HDAC2↓, 1,   HDAC3↓, 1,   MEF2D↑, 1,   other?, 2,   other↓, 4,   other↑, 8,   other↝, 7,  

Protein Folding & ER Stress(tgid=8) ⓘ

ATF6↓, 1,   ER Stress↓, 3,   GRP78/BiP↓, 3,   GRP78/BiP↑, 1,   HSP70/HSPA5↑, 1,   HSP70/HSPA5↝, 1,   HSP90↑, 1,   HSPs↑, 2,   IRE1↓, 1,   UPR↑, 1,  

Autophagy & Lysosomes(tgid=9) ⓘ

autophagy↓, 1,   Beclin-1/ATG6↓, 1,   Beclin-1/ATG6↑, 2,   CTSZ↓, 1,   MitoP↑, 3,   p62↓, 1,   p62↑, 1,   PARK2↑, 2,  

DNA Damage & Repair(tgid=10) ⓘ

DNAdam↓, 4,   DNArepair↑, 1,   P53↓, 2,   SIRT6↑, 1,   γH2AX↓, 1,  

Cell Cycle & Senescence(tgid=11) ⓘ

cellSen↝, 1,   E2Fs↑, 1,   Ki-67↑, 1,   TumCCA↑, 1,  

Proliferation, Differentiation & Cell State(tgid=12) ⓘ

Choline↑, 1,   GH↑, 1,   Ki-67↑, 1,   neuroG↑, 8,   Wnt↑, 1,  

Migration(tgid=13) ⓘ

AntiAg↑, 3,   AP-1↓, 3,   BACH1↓, 1,   Ca+2?, 1,   Ca+2↓, 5,   Ca+2↑, 1,   Ca+2↝, 1,   Cartilage↑, 1,   MMP13↓, 1,   MMP2↓, 3,   MMP9↓, 9,   MMPs↓, 1,   N-cadherin↑, 1,   NFAT↓, 1,   Rho↓, 1,   p‑T-cadherin↓, 1,   TG2/TGase↓, 1,   TGF-β↓, 2,   TGF-β1↑, 1,   TregCell↑, 1,   β-catenin/ZEB1↑, 1,  

Angiogenesis & Vasculature(tgid=14) ⓘ

angioG↑, 1,   CD31/PECAM-1↑, 1,   eNOS↑, 1,   Hif1a↑, 1,   NO↓, 15,   NO↑, 1,   VCAM-1↓, 6,   VEGF↑, 2,  

Barriers & Transport(tgid=15) ⓘ

BBB?, 3,   BBB↓, 10,   BBB↑, 171,   BBB↝, 14,   BBB∅, 4,   CellMemb↑, 1,   CLDN1↝, 1,   CLDN4↑, 1,   CLDN5↑, 1,   CX43/GJA1↑, 1,   EPR↑, 1,   GastroP↑, 2,   GLUT1↑, 1,   GLUT3↑, 1,   GLUT4↑, 3,   memfluid↑, 1,   MMP↑, 14,   MUC19↓, 1,   MUC2↓, 1,   OCLN↑, 2,   THBD↑, 1,   TJ↑, 2,   TJ↝, 1,   TRPM7↓, 3,   TRPM7⇅, 1,   TRPV1↑, 1,   TRPV3↑, 1,   ZO-1↑, 4,   ZO-1↝, 1,  

Immune & Inflammatory Signaling(tgid=16) ⓘ

AIF1/Iba-1↓, 1,   CD4+↑, 1,   CD8+↑, 1,   COX1↓, 1,   COX2/PTGS2↓, 28,   HMGB1↓, 2,   ICAM-1↓, 3,   IFN-γ↓, 1,   IL1↓, 1,   IL10↓, 1,   IL10↑, 2,   IL12↓, 1,   IL17↓, 1,   IL1α↓, 1,   IL1β↓, 33,   IL2↓, 3,   IL23↓, 1,   IL33↓, 1,   IL4↓, 4,   IL6↓, 28,   IL6↑, 2,   IL8↓, 5,   Imm↑, 3,   INF-γ↓, 2,   INF-γ↑, 1,   Inflam↓, 96,   Inflam↑, 2,   IRF3↓, 1,   MCP1/CCL2↓, 4,   MIP‑1α/CCL3↓, 1,   MyD88↓, 2,   NeuroI↓, 5,   NF-kB↓, 36,   NF-kB↑, 2,   p‑NF-kB↓, 3,   NLRP3↓, 14,   p65↓, 1,   PGE2↓, 7,   RAGE↓, 1,   RANTES↓, 2,   TLR2↓, 1,   TLR4↓, 8,   TNF-α↓, 45,   TRAF6↓, 1,   TRIF↓, 1,  

Cellular Microenvironment(tgid=17) ⓘ

GFAP↓, 1,  

Synaptic & Neurotransmission(tgid=18) ⓘ

5HT↑, 8,   Ach↑, 10,   AChE↓, 35,   AChE↑, 1,   ADAM10↑, 2,   ADAM10↝, 1,   BChE↓, 7,   BDNF↑, 26,   BrainVol↑, 1,   CARTPT↑, 1,   ChAT↑, 7,   GABA↓, 1,   GABA↑, 3,   MAOA↓, 5,   MAOB↓, 1,   monoA↑, 1,   NGF↑, 3,   PSD95↑, 3,   SNAP25↑, 2,   TrkB↑, 4,   TrkB↝, 1,  

Protein Aggregation(tgid=19) ⓘ

AGEs↓, 1,   APOE4↓, 1,   APP↓, 8,   cl‑APP↑, 1,   Aβ↓, 76,   Aβ42↓, 3,   BACE/β-secretase↓, 16,   BACE/β-secretase↝, 1,   PSEN1/PS1↑, 1,   tau↓, 18,   p‑tau↓, 18,   β-Amyloid↓, 1,  

Hormonal & Nuclear Receptors(tgid=20) ⓘ

ER(estro)↓, 1,   PPARα↑, 1,   PPARγ↑, 6,  

Drug Metabolism & Resistance(tgid=21) ⓘ

ABC↓, 1,   BioAv↓, 30,   BioAv↑, 52,   BioAv⇅, 1,   BioAv↝, 20,   BioAv∅, 1,   BioEnh↑, 4,   ChemoSen↑, 1,   CompStab↑, 1,   CYP3A2↓, 1,   CYP3A4↓, 1,   DDS↑, 2,   Dose?, 1,   Dose↓, 1,   Dose↑, 3,   Dose↝, 33,   Dose∅, 1,   eff↓, 3,   eff↑, 35,   eff↝, 1,   Half-Life↓, 7,   Half-Life↑, 4,   Half-Life↝, 14,   Half-Life∅, 1,   MRP1/ABCC1↓, 1,   P-gp/ABCB1↓, 6,   P450↓, 1,   selectivity↑, 1,   Synergy↑, 17,  

Clinical Biomarkers(tgid=22) ⓘ

ALAT↓, 5,   anemia↓, 1,   AST↓, 6,   BG↓, 1,   BloodF↑, 3,   BP↓, 8,   BP↝, 1,   BP∅, 1,   creat↓, 2,   CRP↓, 1,   Ferritin↓, 1,   Ferritin↑, 1,   HemoG↑, 1,   IL6↓, 28,   IL6↑, 2,   LDH↓, 3,   NOS2↓, 1,   RAGE↓, 1,   RBC↑, 1,   TC↓, 1,   TMAO↑, 2,  

Functional Outcomes(tgid=23) ⓘ

AntiAge↑, 2,   antiAll↑, 3,   AntiCan↑, 9,   AntiDiabetic↑, 4,   AntiMyl↑, 1,   AntiTum↑, 1,   Bone Healing↑, 1,   cardioP↑, 17,   chemoP↑, 1,   cognitive↓, 1,   cognitive↑, 86,   cognitive↝, 1,   cognitive∅, 2,   diuretic↑, 1,   fatigue↓, 1,   hepatoP↓, 2,   hepatoP↑, 10,   Learn↑, 4,   memory↓, 1,   memory↑, 68,   memory∅, 1,   Mood↑, 6,   motorD↑, 15,   Mucositis↓, 1,   neuroP?, 1,   neuroP↑, 110,   NP/CIPN↓, 1,   Obesity↓, 3,   OS↑, 2,   Pain↓, 3,   radioP↑, 1,   RenoP↓, 1,   RenoP↑, 5,   Risk↓, 3,   Sleep↑, 5,   Strength↑, 5,   Stress↓, 3,   Stroke↓, 9,   toxicity↓, 17,   toxicity↑, 2,   toxicity⇅, 1,   toxicity↝, 3,   toxicity∅, 6,   Weight↓, 1,   Wound Healing↑, 1,  

Infection & Microbiome(tgid=24) ⓘ

AntiBio↑, 6,   AntiFungal↑, 4,   AntiP↑, 2,   AntiViral↑, 4,   Bacteria↓, 7,   GutMicro↑, 18,   Sepsis↓, 3,  

Ingredients & Constituents(tgid=25) ⓘ

Ingr↑, 1,   Ingr↝, 1,  
Total Targets: 449

Scientific Paper Hit Count for: BBB, Blood-Brain Barrier Permeability
14 Selenium NanoParticles
13 Alpha-Lipoic-Acid
11 borneol
10 Curcumin
10 Hydrogen Gas
7 Honokiol
6 Luteolin
6 Methylene blue
6 Mushroom Lion’s Mane, Hericium erinaceus
6 Urolithin
5 Chlorogenic acid
5 Carvacrol
5 EGCG (Epigallocatechin Gallate)
5 Pterostilbene
4 Silver-NanoParticles
4 Berberine
4 Mung Bean Sprouts
4 Ferulic acid
4 Lycopene
4 Quercetin
4 Resveratrol
3 5-Hydroxytryptophan
3 Apigenin (mainly Parsley)
3 Bacopa monnieri
3 Choline
3 Gamma-aminobutyric acid
3 Rosmarinic acid
3 Licochalcone A
3 Rutin
3 Sulforaphane (mainly Broccoli)
2 almonertinib
2 Baicalein
2 beta-carotene(VitA)
2 Caffeic acid
2 Carnosic acid
2 Cinnamon
2 Fisetin
2 Isobavachalcone
2 Isoliquiritigenin
2 Ivermectin
2 Lactoferrin/Talactoferrin
2 Matrine
2 Melatonin
2 Vitamin B3,Niacin
2 S-adenosyl-L-methionine
2 Silymarin (Milk Thistle) silibinin
2 Thymoquinone
2 Turmerones
2 Vitamin B5,Pantothenic Acid
1 1,8-Cineole
1 acetaminophen
1 Anthocyanins
1 Allicin (mainly Garlic)
1 Acetyl-l-carnitine
1 Bevacizumab (brand Avastin)
1 Aromatherapy
1 Ashwagandha(Withaferin A)
1 Astaxanthin
1 Baicalin
1 Beta-Caryophyllene
1 Betulinic acid
1 Brucea javanica
1 Boswellia (frankincense)
1 α-Bisabolol / Chamomile oil
1 Capsaicin
1 Thymol-Thymus vulgaris
1 Cynanbungeigenin C (CBC) and D (CBD)
1 chitosan
1 Chrysin
1 Propolis -bee glue
1 Coenzyme Q10
1 Crocetin
1 Galantamine
1 Cysteamine
1 Deguelin
1 Diclofenac
1 Ginkgo biloba-EGb 761
1 Eugenol
1 Evodiamine
1 Fucoidan
1 Gambogic Acid
1 Geraniol
1 Glabrescione B
1 Gold NanoParticles
1 Hydroxycinnamic-acid
1 Huperzine A/Huperzia serrata
1 Hyperoside
1 Inositol
1 isoflavones
1 isoorientin
1 isoquercitrin
1 Magnolol
1 Isovitexin
1 Vitexin
1 mebendazole
1 MCT oil
1 Magnetic Fields
1 Mangiferin
1 Moringa oleifera
1 Methylsulfonylmethane
1 L-Theanine
1 Myricetin
1 Myrrh
1 nicotinamide adenine dinucleotide
1 Nimbolide
1 Olive Oil
1 HydroxyTyrosol
1 Oleuropein
1 Protocatechuic acid
1 Propranolol
1 Rauwolfia serpentina/Indian Snakeroot
1 Metformin
1 Taurine
1 Vitamin C (Ascorbic Acid)
Query results interpretion may depend on "conditions" listed in the research papers.
Such Conditions may include : 
  -low or high Dose
  -format for product, such as nano of lipid formations
  -different cell line effects
  -synergies with other products 
  -if effect was for normal or cancerous cells

Filter Conditions: Pro/AntiFlg:%  IllCat:%  CanType:%  Cells:%  prod#:%  Target#:1123  State#:%  Dir#:%
  wNotes=0  sortOrder:rid,rpid

 

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