chemoP Cancer Research Results

chemoP, ChemoProtective: Click to Expand ⟱
Source:
Type:
Protects normal cells against the effect of Chemo.
Scientific Papers found: Click to Expand⟱
5800- MET,    Metformin as anticancer agent and adjuvant in cancer combination therapy: Current progress and future prospect
- Review, Var, NA
ChemoSen↑, RadioS↑, Imm↑, *AntiDiabetic↑, *AMPK↑, TumCP↓, hepatoP↑, ATP↓, AMP↑, glucoNG↓, ROS↑, compI↓, DNAdam↑, CSCs↓, NP/CIPN↓, chemoP↑, toxicity↓, Trx↓, Synergy↑, cycD1/CCND1↓, CDK4↓, CDK6↓, cycE/CCNE↓, CDK2↓,
8485- MF,  doxoR,    Static magnetic field promotes the doxorubicin toxicity effects on osteosarcoma cells
- in-vitro, OS, G292
tumCV↓, Dose↝, Apoptosis↑, ROS↑, i-Iron↓, *Ca+2↓, *Iron↑, *chemoP↑, ROS↓, ChemoSen↑, selectivity↑,
501- MF,    Low Intensity and Frequency Pulsed Electromagnetic Fields Selectively Impair Breast Cancer Cell Viability
- in-vitro, BC, MCF7 - in-vitro, Nor, MCF10
Apoptosis↑, *toxicity↓, ChemoSen↑, chemoP↑, selectivity↑, DNAdam↑,
198- MFrot,  MF,    Biological effects of rotating magnetic field: A review from 1969 to 2021
- Review, Var, NA
AntiCan↑, breath↑, Pain↓, Appetite↑, Strength↑, BowelM↑, TumMeta↓, TumCCA↑, ETC↓, MMP↓, TumCD↑, selectivity↑, ROS↑, Casp3↑, TumCG↓, TumCCA↑, ChrMod↑, TumMeta↓, Imm↑, DCells↑, Akt↓, OS⇅, toxicity↓, QoL↑, hepatoP↑, Pain↓, Weight↑, Strength↑, Sleep↑, IL6↓, CD4+↑, CD8+↑, Ca+2↑, radioP↑, chemoP↑, *BMD↑, *AntiAge↑, *AMPK↑, *P21↓, *P53↓, *mTOR↓, *OS↑, *β-Endo↑, *5HT↓,
8666- MLT,    Clinical impact of melatonin on breast cancer patients undergoing chemotherapy; effects on cognition, sleep and depressive symptoms: A randomized, double-blind, placebo-controlled trial
- Trial, BC, NA
other↝, cognitive↑, memory↑, Verbal↑, neuroP↑, BDNF↓, TrkB↓, chemoP↑,
8687- MLT,    Melatonin induces cell cycle arrest and suppresses tumor invasion in urinary bladder urothelial carcinoma
- in-vitro, CRC, T24/HTB-9 - in-vitro, Bladder, UMUC3
TumCP↓, TumCCA↑, Hif1a↓, NF-kB↓, Bcl-2↓, ROS↑, Akt↓, PCNA↓, cycD1/CCND1↓, BAX↓, Apoptosis?, ChemoSen↑, Wnt↓, β-catenin/ZEB1↓, COX2/PTGS2↓, PGE2↓, NF-kB↓, PI3K↓, Akt↓, P53↑, P21↑, *cardioP?, *NRF2↑, *HO-1↑, *RenoP↑, chemoP↑,
8675- MLT,    Melatonin combined with antineoplastic drugs or natural products for cancer treatment: An update
- Review, Var, NA
ChemoSen↑, TumCP↓, TumCMig↓, CSCs↓, MDR1↓, chemoP?, IL1β↓, IL6↓, IL8↓, TNF-α↓, COX2/PTGS2↓, iNOS↓, Bcl-2↓, Mcl-1↓, IAP1↓, survivin↓, PCNA↓, Ki-67↓, CC(CDKs/cyclins)↓, TumCMig↓, TumCI↓, Fibronectin↓, Vim↓, N-cadherin↓, MMP2↓, MMP9↓, Synergy↑, Synergy↑, OCT4↓, Nanog↓, ERCC1↓, P-gp/ABCB1↓, EMT↓, Synergy↑, ChemoSen↑,
1775- MLT,  Chemo,  Rad,    A Systematic Review of the Chemo/Radioprotective Effects of Melatonin against Ototoxic Adverse Effects Induced by Chemotherapy and Radiotherapy
- Review, Var, NA
chemoP↑, radioP↑, antiOx↑, Inflam↑,
1777- MLT,    Melatonin as an antioxidant: under promises but over delivers
- Review, Var, NA
*ROS↓, *Fenton↓, *antiOx↑, *toxicity∅, *GPx↑, *GSR↑, *GSH↑, *NO↓, *Iron↓, *Copper↓, *IL1β↓, *iNOS↓, *Casp3↓, *BBB↑, *RenoP↑, chemoP↑, *Ca+2↝, eff↑, *PKCδ?, ChemoSen↑, eff↑, Akt↓, DR5↑, selectivity↑, ROS↑, Synergy↑,
1779- MLT,    Therapeutic Potential of Melatonin Counteracting Chemotherapy-Induced Toxicity in Breast Cancer Patients: A Systematic Review
- Review, BC, NA
QoL↑, OS↑, Dose∅, antiOx↑, ROS↑, SOD↑, Catalase↑, GPx↑, Risk↓, NK cell↑, IL1β↓, IL6↓, TNF-α↓, radioP↑, chemoP↑, TumVol↓, TumMeta↓, angioG↓, ChemoSen↑, eff↑,
8912- MO,    Anticancer effect of Moringa oleifera in oral squamous cell carcinoma: a systematic review
- Review, Oral, NA
*antiOx↑, *Inflam↓, *AntiCan↑, *chemoPv↑, *Ingr↝, *AntiDiabetic↑, *hepatoP↑, *Bacteria↓, *AntiFungal↑, Apoptosis↑, ROS↑, DNAdam↑, Casp3↑, TumCCA↑, ROS↓, chemoP↑,
8875- MOR,    Neuroprotective Effect of Morin Against Chemical-Induced Neurotoxicities and Neurodegenerative Disease Models
- Review, AD, NA
*neuroP↑, *Inflam↓, *antiOx↑, *chemoP↑, *NRF2↑, *HO-1↑, *SOD↑, *Catalase↑, *GPx↑, *GSH↑, *ROS↓, *MDA↓, *NO↓, *TLR4↓, *NF-kB↓, *ERK↓, *TNF-α↓, *IL1β↓, *IL6↓, *iNOS↓, *COX2/PTGS2↓, *NLRP3↓,
8883- MOR,  5-FU,    Morin Mitigates 5-Fluorouracil-Induced Nephrotoxicity by Activating Nrf2/HO-1 and FXR, and Suppressing ERK/VCAM-1 and NF-κB Pathways
- in-vivo, Nor, NA
*Inflam↓, *antiOx↑, *Dose↝, *Urea↓, *creat↓, *ROS↓, *NRF2↑, *HO-1↑, *NR1H4↑, *RenoP↑, *TNF-α↓, *IL6↓, *ERK↓, *VCAM-1↓, *NF-kB↓, *chemoP↑,
8882- MOR,  Cisplatin,    Morin hydrate protects against cisplatin-induced testicular toxicity by modulating ferroptosis and steroidogenesis genes' expression and upregulating Nrf2/Heme oxygenase-1
- in-vivo, Nor, NA
*antiOx↑, *Inflam↓, *Apoptosis↓, *Dose?, *SOD↑, *GPx↑, *NRF2↑, *HO-1↑, *MDA↓, *other↑, *Ferroptosis↓, *Iron↓, *ROS↓, *other↓, ChemoSen↑, *chemoP↑, *selectivity↑,
8879- MOR,  doxoR,    Synergistic Effects of Morin and Doxorubicin Overcome Chemoresistance in Ovarian Cancer: Preclinical Insights From in vitro and in vivo Models
- vitro+vivo, Ovarian, OVCAR-3 - NA, Melanoma, A2780S
Dose↝, ChemoSen↑, cycA1/CCNA1↓, cycD1/CCND1↓, TumVol↓, Apoptosis↑, TumCCA↑, ROS↝, chemoP↑, TumAuto↑, ROS↓, SOD↑, Catalase↑, GSH↑, MDA↓, cardioP↑, mTOR↓, PI3K↓, Akt↓, Bcl-2↓, Casp3↑, Casp9↑, LC3A↑, ATG5↑, Beclin-1/ATG6↑,
8770- MSM,  Cisplatin,    Methylsulfonylmethane (MSM) Mitigates Cisplatin-Induced Early Oxidative Testicular Dysfunction Through Modulation of Antioxidant Defense and GPX4 Response
- in-vivo, Nor, NA
*Dose?, *lipid-P↓, *SOD↑, *Catalase↑, *GPx↑, *testos↑, *GPx4↓, *chemoP↑,
1807- NarG,    A Systematic Review of the Preventive and Therapeutic Effects of Naringin Against Human Malignancies
- Review, Var, NA
AntiTum↑, TumCP↓, tumCV↓, TumCCA↑, Mcl-1↓, RAS↓, e-Raf↓, VEGF↓, AntiAg↑, MMP2↓, MMP9↓, TIMP2↑, TIMP1↑, p38↓, Wnt↓, β-catenin/ZEB1↑, Casp↑, P53↑, BAX↑, COX2/PTGS2↓, GLO-I↓, CYP1A1↑, lipid-P↓, p‑Akt↓, p‑mTOR↓, VCAM-1↓, P-gp/ABCB1↓, survivin↓, Bcl-2↓, ROS↑, ROS↑, MAPK↑, STAT3↓, chemoP↑,
4643- OLE,  HT,    Use of Oleuropein and Hydroxytyrosol for Cancer Prevention and Treatment: Considerations about How Bioavailability and Metabolism Impact Their Adoption in Clinical Routine
- Review, Var, NA
TumCCA↑, Apoptosis↑, ER Stress↑, UPR↑, CHOP/DDIT3↑, ROS↑, Bcl-2↓, NOX4↑, Hif1a↓, MMP2↓, MMP↓, VEGF↓, Akt↓, NF-kB↓, p65↓, SIRT3↓, mTOR↓, Catalase↓, SOD2↓, FASN↓, STAT3↓, HDAC2↓, HDAC3↓, BAD↑, BAX↑, Bak↑, Casp3↑, Casp9↑, PARP↑, P53↑, P21↑, p27/CDKN1B↑, Half-Life↝, BioAv↓, BioAv↓, selectivity↑, RadioS↑, *ROS↓, *GSH↑, *MDA↓, *SOD↑, *Catalase↑, *NRF2↑, *chemoP↑, *Inflam↓, PPARγ↑,
4626- OLE,    A Comprehensive Review on the Anti-Cancer Effects of Oleuropein
- Review, Var, NA
Risk↓, Dose↑, TumCP↓, NF-kB↓, COX2/PTGS2↓, Akt↓, P53↑, BAX↑, Bcl-2↓, HIF-1↓, ROS↑, HO-1↑, chemoP↑, TumCCA↑, FASN↓,
7290- PacT,  Aidi,    Clinical efficacy and safety of Aidi injection plus paclitaxel-based chemotherapy for advanced non-small cell lung cancer: A meta-analysis of 31 randomized controlled trials following the PRISMA guidelines
- in-vitro, NSCLC, NA
Dose↝, QoL↑, hepatoP↑, GastroP↑, chemoP↑, Dose↝,
2064- PB,  Rad,    Phenylbutyrate Attenuates the Expression of Bcl-XL, DNA-PK, Caveolin-1, and VEGF in Prostate Cancer Cells
- in-vitro, Pca, PC3 - in-vitro, Pca, DU145 - in-vitro, Pca, LNCaP
Bcl-xL↓, Cav1↓, VEGF↓, RadioS↑, chemoP↑, HDAC↓, *toxicity↓, Diff↑, Prot↓,
2380- PBG,    Potential Strategies for Overcoming Drug Resistance Pathways Using Propolis and Its Polyphenolic/Flavonoid Compounds in Combination with Chemotherapy and Radiotherapy
- Review, Var, NA
Hif1a↓, Glycolysis↓, PKM2↓, LDHA↓, GLUT2↓, HK2↓, PFK1↓, PDK1 / PDPK1↓, chemoP↓, radioP↑,
4924- PEITC,    Nutri-PEITC Jelly Significantly Improves Progression-Free Survival and Quality of Life in Patients with Advanced Oral and Oropharyngeal Cancer: A Blinded Randomized Placebo-Controlled Trial
- Trial, Oral, NA
QoL↑, P53↑, OS↑, Cyt‑c↝, other↝, ROS↑, selectivity↑, P21↑, TumCCA↑, Dose↝, BioAv↑, Weight↑, chemoP↑,
3595- PI,    Black pepper and health claims: a comprehensive treatise
- Review, Var, NA - Review, AD, NA
*antiOx↑, *ROS↓, *chemoP↑, TumCG↓, *cognitive↑, *MMPs↓, *PGE2↓, *AP-1↓, *5LO↓, *COX1↓, *other↑, *other↑, *other↑, *SOD↑, *Catalase↑, *GSTs↑, *GSR↑, *other↑, *Weight↓, *BioEnh↑, *BioAv↑, *Synergy↑, *CYP3A2↓, *neuroP↑, *BP↓, *other↑,
4965- PSO,  Cisplatin,    The synergistic antitumor effects of psoralidin and cisplatin in gastric cancer by inducing ACSL4-mediated ferroptosis
- vitro+vivo, GC, HGC27 - vitro+vivo, GC, MKN45
TumCP↓, TumCMig↓, TumCI↓, TumCG↓, *toxicity↓, Synergy↑, Ferroptosis↑, ACSL4↑, GPx4↓, ChemoSen↑, chemoP↑, AntiTum↑, Sepsis↓,
2303- QC,  doxoR,    Quercetin greatly improved therapeutic index of doxorubicin against 4T1 breast cancer by its opposing effects on HIF-1α in tumor and normal cells
- in-vitro, BC, 4T1 - in-vivo, NA, NA
cardioP↑, hepatoP↑, TumCG↓, OS↑, ChemoSen↑, chemoP↑, Hif1a↓, *Hif1a↑, selectivity↑, TumVol↓, OS↑,
4787- QC,    Quercetin: A Phytochemical with Pro-Apoptotic Effects in Colon Cancer Cells
- Review, CRC, NA
Inflam↓, AntiCan↑, Apoptosis↑, MMP↓, P53↑, BAX↑, Casp3↑, Casp9↑, Bcl-2↓, NF-kB↓, IL6↓, IL1β↓, *antiOx↑, *lipid-P↓, *ROS↓, MAPK↓, JAK↓, STAT↓, PI3K↓, Akt↓, chemoP↑, ROS⇅, DNAdam↑, ChemoSen↝,
68- QC,  BaP,    Differential protein expression of peroxiredoxin I and II by benzo(a)pyrene and quercetin treatment in 22Rv1 and PrEC prostate cell lines
- in-vitro, Pca, 22Rv1 - in-vitro, Pca, PrEC
PrxI∅, PrxII∅, *toxicity↓, ROS↓, ROS↑, ROS∅, chemoP↑, PrxII↑, i-H2O2↓,
3016- RosA,    Rosmarinic Acid Inhibits Cell Growth and Migration in Head and Neck Squamous Cell Carcinoma Cell Lines by Attenuating Epidermal Growth Factor Receptor Signaling
- in-vitro, HNSCC, UM-SCC-6 - in-vitro, HNSCC, UM-SCC-10B
chemoP↓, EGF↓, tumCV↓, TumCMig↓, ROS↓, PI3K↓, Akt↓, ERK↓, antiOx↑, p‑EGFR↓,
1749- RosA,    Rosmarinic Acid and Related Dietary Supplements: Potential Applications in the Prevention and Treatment of Cancer
- Review, Var, NA
antiOx↑, eff↑, *toxicity↝, *BioAv↑, *ROS↓, SOD↑, Catalase↑, GPx↑, lipid-P↓, P450↓, chemoP↑, hepatoP↑, ChemoSen↑,
7951- RT,  BuckWS,    The anticancer potential of the dietary polyphenol rutin: Current status, challenges, and perspectives
- Review, Nor, NA
*Dose↝, *BioAv↓, *BioAv↓, *BioAv↓, *BioAv↓, *BioAv↝, TumCP↓, Risk↓, *radioP↑, chemoPv↑, TumCCA↑, GSK‐3β↑, Wnt↓, β-catenin/ZEB1↓, ROS↑, BAX↑, Casp3↑, Casp8↑, Casp9↑, PARP↑, Beclin-1/ATG6↑, ATG5↑, LC3II↑, DNMT1↓, P21↑, CDK1↑, CycB/CCNB1↓, TNF-α↑, VEGF↓, IL1β↓, NF-kB↓, AP-1↓, MYCN↓, AMPK↑, MAPK↓, PI3K↓, Akt↓, cMET↓, P-gp/ABCB1↓, MRP1/ABCC1↓, ABCG2↓, MMPs↓, TNF-α↓, iNOS↓, COX2/PTGS2↓, angioG↓, STAT3↓, *chemoP↑, *ROS↓, *MDA↓, *P53↓, *Casp3↓, *Casp9↓, *JNK↓, *TNF-α↓, *p38↓, *MAPK↓, GSH↓, ChemoSen↑, *hepatoP↑, *COX1↓, *COX2/PTGS2↓, *15-LOX/ALOX15↓, RenoP↑, *toxicity↓,
7954- RT,    Rutin : therapeutic potential and recent advances in drug delivery
- Review, Nor, NA - Review, IBD, NA
*antiOx↑, *antiAll↑, *Inflam↓, *AntiTum↑, *Bacteria↓, *AntiViral↑, *BioAv↓, *AntiArt↑, *PLA2↓, *chemoP↑, *ROS↓, *Casp3↓, *TNF-α↓, *NF-kB↓, *cardioP↑, *Stroke↓, *TG/TAG↓, *FFA/NEFA↓, *LDL↓, *HDL↑, *AntiDiabetic↑, *MPO↓, *NF-kB↓, *BioAv↓, *BioAv↝,
4749- Se,  Chemo,  antiOx,    Selenium as an element in the treatment of ovarian cancer in women receiving chemotherapy
- Trial, Ovarian, NA
*GSH↑, *MDA↑, *other?, *other?, *chemoP↑,
4744- Se,  Chemo,  antiOx,    Ingestion of selenium and other antioxidants during prostate cancer radiotherapy: A good thing?
- Review, Pca, NA
Risk↓, chemoP↑,
4717- Se,    A systematic review of Selenium as a complementary treatment in cancer patients
- Review, Var, NA
*antiOx↑, eff↝, radioP↑, chemoP↑, *selenoP↑, *GPx↑, TrxR↑, *ROS↓,
4711- Se,    Association of selenium status and blood glutathione concentrations in blacks and whites
- Human, Nor, NA
Risk↓, chemoP↑, *GSH↑,
4715- Se,    The Interaction of Selenium with Chemotherapy and Radiation on Normal and Malignant Human Mononuclear Blood Cells
- in-vitro, Var, NA
chemoP↑, radioP↑, selectivity↑, ChemoSen↑, GSH↓, *GSH↑, *DNAdam↓, DNAdam↑, eff↑,
4751- Se,  Chemo,    Selenium Protects Against Toxicity Induced by Anticancer Drugs and Augments Antitumor Activity: A Highly Selective, New, and Novel Approach for the Treatment of Solid Tumors
- in-vivo, Var, NA
Dose↝, ChemoSen↑, chemoP↑,
4755- Se,  Chemo,    Selenium Prevention of Alopecia, Bladder and Kidney Toxicity Induced by Chemotherapeutic Agents
- in-vitro, Var, NA
chemoP↑, creat↓, BUN↓,
4754- Se,  Chemo,    The effect of selenium yeast in the prevention of adverse reactions related to platinum-based combination therapy in patients with malignant tumors
- Trial, Var, NA
chemoP↑, QoL↑, chemoP↑, Pain↓,
4757- Se,  Chemo,    The protective role of selenium on the toxicity of cisplatin-contained chemotherapy regimen in cancer patients
- Trial, Var, NA
Dose↝, *ALP↓, chemoP↑,
4720- SeNPs,    Selenium Nanoparticle in the Management of Oxidative Stress During Cancer Chemotherapy
- Review, Var, NA
*toxicity↓, *antiOx↑, chemoP↑,
4734- SeNPs,  CPT-11,    Cytotoxicity and therapeutic effect of irinotecan combined with selenium nanoparticles
- in-vitro, CRC, HCT8 - in-vivo, NA, NA
chemoP↑, ChemoSen↑, P53↑, Apoptosis↑, TumCG↓, Casp↑, Dose↝, NRF2↓, selectivity↑, *NRF2↑,
2553- SFN,    Mechanistic review of sulforaphane as a chemoprotective agent in bladder cancer
- Review, Bladder, NA
antiOx↓, Inflam↓, ChemoSen↑, ROS⇅, *NRF2↑, *GSH↑, Catalase↑, HO-1↑, NAD↑, chemoP↑,
3303- SIL,    Exploring the anti-cancer and antimetastatic effect of Silymarin against lung cancer
- Review, Var, NA
chemoP↑, radioP↑,
3307- SIL,    Flavolignans from Silymarin as Nrf2 Bioactivators and Their Therapeutic Applications
- Review, Var, NA
*NRF2↑, *antiOx↑, *chemoP↑, *Inflam↓, *BioAv↑, Synergy↑, *NQO1↑, TNF-α↓, IL6↓, *GSH↑, *ROS↓, *MDA↓, Synergy↑, *hepatoP↑, *GPx↑, *SOD↑, *Catalase↑, *HO-1↑, *neuroP↑,
3308- SIL,    Structural basis of Nrf2 activation by flavonolignans from silymarin
- Analysis, Nor, NA
*antiOx↑, *chemoP↑, *NRF2↑,
3301- SIL,    Critical review of therapeutic potential of silymarin in cancer: A bioactive polyphenolic flavonoid
- Review, Var, NA
Inflam↓, TumCCA↑, Apoptosis↓, TumMeta↓, TumCG↓, angioG↓, chemoP↑, radioP↑, p‑ERK↓, p‑p38↓, p‑JNK↓, P53↑, Bcl-2↓, Bcl-xL↓, TGF-β↓, MMP2↓, MMP9↓, E-cadherin↑, Wnt↓, Vim↓, VEGF↓, IL6↓, STAT3↓, *ROS↓, IL1β↓, PGE2↓, CDK1↓, CycB/CCNB1↓, survivin↓, Mcl-1↓, Casp3↑, Casp9↑, cMyc↓, COX2/PTGS2↓, Hif1a↓, CXCR4↓, CSCs↓, EMT↓, N-cadherin↓, PCNA↓, cycD1/CCND1↓, ROS↑, Synergy↑, Synergy↑, Synergy↑, HER2/EBBR2↓,
3294- SIL,    Silymarin: a review on paving the way towards promising pharmacological agent
- Review, Nor, NA - Review, Arthritis, NA
*hepatoP↑, *Inflam↓, *chemoP↑, *glucose↓, *antiOx↑, *ROS↓, *ACC↓, *FASN↓, *radioP↑, *NF-kB↓, *TGF-β↓, *AST↓, *α-SMA↝, *Synergy↑, *neuroP↑, Synergy↑, ROS↓,
3293- SIL,    Silymarin (milk thistle extract) as a therapeutic agent in gastrointestinal cancer
- Review, Var, NA
hepatoP↑, TumMeta↓, Inflam↓, chemoP↑, radioP↑, Half-Life↝, *GSTs↑, p‑JNK↑, BAX↑, p‑p38↑, cl‑PARP↑, Bcl-2↓, p‑ERK↓, TumVol↓, Synergy↑, TumCCA↑, STAT3↓, Mcl-1↓, survivin↓, Bcl-xL↓, Casp3↑, Casp9↑, eff↑, CXCR4↓, Dose↝,

Showing Research Papers: 151 to 200 of 228
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* indicates research on normal cells as opposed to diseased cells
Total Research Paper Matches: 228

Pathway results for Effect on Cancer / Diseased Cells:


Redox & Oxidative Stress(tgid=1) ⓘ

antiOx↓, 1,   antiOx↑, 8,   antiOx⇅, 1,   Bil↝, 1,   Catalase↓, 2,   Catalase↑, 4,   GPx↓, 1,   GPx↑, 2,   GPx4↓, 3,   GSH↓, 15,   GSH↑, 3,   GSH∅, 1,   GSR↓, 1,   GSTs↓, 1,   GSTs↑, 1,   H2O2↑, 1,   i-H2O2↓, 1,   HO-1↓, 3,   HO-1↑, 3,   HO-2↑, 1,   i-Iron↓, 1,   c-Iron↑, 1,   lipid-P↓, 4,   lipid-P↑, 4,   MDA↓, 2,   MDA↑, 1,   NOX4↑, 1,   NQO1↓, 1,   NQO1↑, 1,   Nrf1↑, 1,   NRF2↓, 5,   NRF2↑, 6,   Prx6↑, 1,   PrxI↓, 1,   PrxI∅, 1,   PrxII↑, 1,   PrxII∅, 1,   ROS↓, 11,   ROS↑, 76,   ROS⇅, 6,   ROS↝, 1,   ROS∅, 1,   i-ROS↑, 1,   mt-ROS↑, 3,   SOD↓, 3,   SOD↑, 3,   SOD2↓, 2,   Thiols↓, 1,   Trx↓, 1,   TrxR↑, 1,   uricA↓, 1,   VitC↓, 1,   VitE↓, 1,   xCT/SLC7A11↓, 1,  

Metal & Cofactor Biology(tgid=2) ⓘ

IronCh↑, 2,  

Mitochondria & Bioenergetics(tgid=3) ⓘ

CDC2↓, 1,   CDC25↓, 1,   compI↓, 2,   compII↓, 1,   EGF↓, 1,   ETC↓, 2,   Insulin↓, 1,   MKK7↓, 1,   mtDam↓, 1,   mtDam↑, 5,   PGC-1α↑, 1,   SIRT3↓, 1,   SIRT3↑, 1,  

Core Metabolism/Glycolysis(tgid=4) ⓘ

12LOX?, 1,   5LO↓, 1,   ACSL4↑, 2,   ALAT↓, 4,   AMP↑, 1,   AMPK↑, 2,   p‑AMT/GCST/T-protein↑, 1,   ATP↓, 4,   BHB↑, 1,   FASN↓, 3,   GLO-I↓, 1,   glucoNG↓, 1,   glucose↝, 1,   GlucoseCon↓, 1,   GlucoseCon∅, 1,   GlutMet↓, 1,   Glycolysis↓, 4,   GSK‐3β↓, 3,   GSK‐3β↑, 5,   p‑GSK‐3β↓, 1,   H2S↑, 1,   HK2↓, 2,   HMG-CoA↓, 1,   HMGCS2↑, 1,   lactateProd∅, 1,   LDHA↓, 3,   lipoGen↓, 1,   NAD↑, 1,   NADPH↓, 1,   PCK1↓, 1,   PDK1 / PDPK1↓, 2,   PFK1↓, 1,   PKM2↓, 3,   PPP↓, 1,   SCD1↓, 1,   SIRT1↓, 2,   SIRT1↑, 2,   SREBP1/SREBF1↓, 1,   TCA↓, 1,   Warburg↓, 1,  

Cell Death(tgid=5) ⓘ

AIF↑, 4,   APAF1↑, 3,   Apoptosis?, 1,   Apoptosis↓, 4,   Apoptosis↑, 61,   m-Apoptosis↑, 1,   ASC↓, 1,   BAD↓, 1,   BAD↑, 1,   Bak↑, 2,   BAX↓, 1,   BAX↑, 29,   Bax:Bcl2↑, 3,   Bcl-2↓, 31,   Bcl-2↑, 1,   Bcl-xL↓, 8,   BIM↓, 1,   BIM↑, 1,   Casp↑, 19,   Casp1↓, 1,   Casp12↑, 1,   Casp3↑, 30,   cl‑Casp3↑, 3,   proCasp3↑, 1,   Casp7↑, 4,   cl‑Casp7↑, 2,   Casp8↑, 7,   proCasp8↑, 1,   Casp9↓, 2,   Casp9↑, 17,   cl‑Casp9↑, 3,   proCasp9↑, 1,   cFLIP↓, 1,   Cyt‑c↑, 21,   Cyt‑c↝, 1,   Diablo↑, 2,   DR5↑, 5,   Fas↓, 1,   Fas↑, 5,   FasL↓, 1,   FasL↑, 1,   Ferroptosis↑, 5,   GSDMD↑, 1,   IAP1↓, 4,   IAP2/BIRC3↓, 4,   iNOS↓, 6,   Mcl-1↓, 6,   p‑MDM2↓, 1,   MOMP↑, 1,   p38↓, 1,   p38↑, 6,   p‑p38↓, 3,   p‑p38↑, 2,   Pyro↑, 1,   survivin↓, 15,   TumCD↓, 1,   TumCD↑, 8,   XIAP↓, 7,   YAP/TEAD↓, 1,   YAP/TEAD↝, 1,  

Kinase & Signal Transduction(tgid=6) ⓘ

Akt↓, 37,   Akt↑, 2,   p‑Akt↓, 7,   p‑Akt↑, 1,   cMET↓, 1,   p‑cMET↑, 1,   cSrc↓, 1,   EGFR↓, 8,   EGFR↑, 1,   p‑EGFR↓, 1,   ERK↓, 21,   p‑ERK↓, 3,   p‑ERK↑, 1,   HCAR2↑, 1,   HER2/EBBR2↓, 1,   HGF/c-Met↓, 2,   IKKα↓, 1,   IκB↓, 1,   JAK↓, 2,   JAK1↓, 2,   JAK2↓, 1,   JNK↓, 2,   JNK↑, 4,   p‑JNK↓, 1,   p‑JNK↑, 3,   MAPK↓, 13,   MAPK↑, 4,   MEK↓, 2,   MKK4↓, 1,   mTOR↓, 15,   p‑mTOR↓, 1,   mTORC2↓, 1,   p42↓, 1,   p‑p70S6↑, 1,   PI3K↓, 30,   PI3K↑, 2,   p‑PI3K↓, 3,   PKCδ↓, 3,   PTEN↓, 1,   PTEN↑, 4,   Raf↓, 2,   e-Raf↓, 1,   RAS↓, 5,   RAS↑, 1,   Sp1/3/4↓, 1,   p‑Src↓, 1,   STAT↓, 2,   STAT3↓, 17,   p‑STAT3↓, 2,   p‑STAT6↓, 1,  

Transcription & Epigenetics(tgid=7) ⓘ

ATF4↑, 1,   ChrMod↑, 1,   cJun↓, 1,   cJun↑, 1,   cMyc↓, 4,   cMyc↑, 1,   DNMT1↓, 1,   DNMT3B↓, 1,   DNMTs↓, 2,   EZH2↓, 1,   FOXO↑, 2,   FOXO1↑, 1,   H3↓, 1,   p‑H3↓, 1,   H4↓, 1,   HATs↑, 2,   HDAC↓, 10,   HDAC2↓, 1,   HDAC3↓, 1,   miR-106b↓, 1,   miR-124-3p↓, 1,   miR-203↑, 1,   miR-34a↑, 1,   Myc↑, 1,   MYCN↓, 1,   OCT4↓, 2,   other?, 1,   other↑, 2,   other↝, 10,   PhotoS↑, 2,   Prot↓, 1,   sonoS↑, 1,   tumCV↓, 14,  

Protein Folding & ER Stress(tgid=8) ⓘ

ATF6↑, 2,   CHOP/DDIT3↓, 1,   CHOP/DDIT3↑, 5,   eIF2α↑, 2,   p‑eIF2α↑, 1,   ER Stress↑, 7,   GRP78/BiP↑, 3,   GRP94↑, 1,   HSP70/HSPA5↓, 1,   HSP90↓, 2,   IRE1∅, 1,   NQO2↑, 1,   p‑PERK↑, 1,   UPR↑, 3,  

Autophagy & Lysosomes(tgid=9) ⓘ

ATG5↑, 3,   Beclin-1/ATG6↑, 4,   LC3‑Ⅱ/LC3‑Ⅰ↑, 1,   LC3A↑, 1,   LC3II↑, 5,   LC3s↑, 1,   p62↓, 1,   TumAuto↑, 8,   TumAuto↝, 2,  

DNA Damage & Repair(tgid=10) ⓘ

ATM↑, 1,   DNAdam↓, 1,   DNAdam↑, 18,   DNArepair↓, 1,   ERCC1↓, 1,   P53?, 1,   P53↓, 1,   P53↑, 21,   p‑P53↑, 2,   PARP↑, 5,   cl‑PARP↓, 1,   cl‑PARP↑, 19,   PCNA↓, 10,   Telomerase↓, 3,   TOP1↓, 2,   TOP2↓, 1,   γH2AX↑, 2,  

Cell Cycle & Senescence(tgid=11) ⓘ

CC(CDKs/cyclins)↓, 1,   CDK1↓, 2,   CDK1↑, 1,   CDK2↓, 5,   CDK4↓, 9,   CDK6↓, 2,   CDK6↑, 1,   CHK1↓, 1,   CHK1↑, 1,   Chk2↑, 1,   Cyc↓, 1,   cycA1/CCNA1↓, 1,   CycB/CCNB1↓, 5,   CycB/CCNB1↑, 1,   cycD1/CCND1↓, 17,   cycE/CCNE↓, 4,   E2Fs↓, 1,   GADD34↑, 1,   GADD45A↑, 2,   Ki-67↓, 7,   mitA↑, 1,   P21↓, 1,   P21↑, 14,   p27/CDKN1B↓, 1,   p27/CDKN1B↑, 5,   pRB↓, 1,   p‑pRB↓, 2,   RB1↑, 1,   TumCCA↓, 2,   TumCCA↑, 53,  

Proliferation, Differentiation & Cell State(tgid=12) ⓘ

ALDH↓, 1,   BMPs↑, 1,   CD133↓, 1,   CD34↓, 1,   cFos↑, 1,   CSCs?, 1,   CSCs↓, 9,   Diff↑, 2,   FGF↓, 1,   HH↓, 1,   HH↝, 1,   IGF-1↓, 4,   IGFBP3↑, 1,   Ki-67↓, 7,   LRP6↓, 1,   mTORC1↓, 1,   Nanog↓, 1,   Nestin↓, 1,   NOTCH↓, 2,   NOTCH1↓, 7,   OGFr↑, 3,   SCF↓, 1,   Shh↓, 1,   TumCG↓, 27,   TumCG↑, 1,   TumCP↓, 51,   TumCP↑, 3,   Wnt↓, 11,  

Migration(tgid=13) ⓘ

AntiAg↑, 1,   AP-1↓, 2,   AXL↓, 2,   BACH1↓, 1,   CA↓, 1,   Ca+2↓, 1,   Ca+2↑, 9,   Cav1↓, 1,   Cdc42↓, 1,   Cofilin↓, 1,   E-cadherin↓, 2,   E-cadherin↑, 6,   EMT↓, 12,   EpCAM↓, 1,   F-actin↓, 1,   FAK↓, 3,   p‑FAK↓, 2,   fascin↓, 1,   Fibronectin↓, 1,   ITGB1↓, 1,   LAMs↓, 1,   MALAT1↓, 1,   MET↓, 1,   p‑MET↓, 1,   MMP1↓, 1,   MMP13↓, 1,   MMP2↓, 20,   MMP3↓, 2,   MMP7↓, 1,   MMP9↓, 21,   MMPs↓, 12,   N-cadherin↓, 6,   PDGF↓, 2,   Rac1↓, 1,   Rho↓, 2,   ROCK1↓, 1,   Slug↓, 1,   Snail↓, 3,   TGF-β↓, 5,   TGF-β1↓, 1,   TIMP1↑, 5,   TIMP2↑, 2,   TumCI↓, 19,   TumCMig↓, 23,   TumMeta↓, 25,   TumMeta↑, 1,   Twist↓, 3,   Tyro3↓, 1,   uPA↓, 4,   Vim↓, 7,   Vim↑, 1,   Zeb1↓, 2,   β-catenin/ZEB1↓, 13,   β-catenin/ZEB1↑, 1,  

Angiogenesis & Vasculature(tgid=14) ⓘ

angioG↓, 32,   angioG↑, 1,   CD31/PECAM-1↓, 3,   HIF-1↓, 3,   Hif1a↓, 21,   LOX1↓, 1,   VCAM-1↓, 2,   VEGF↓, 30,   VEGFR2/KDR/Flk1↓, 5,  

Barriers & Transport(tgid=15) ⓘ

BBB↑, 2,   CellMemb↑, 1,   CLDN1↓, 1,   EPR↑, 2,   GastroP↑, 1,   GLUT1↓, 1,   GLUT2↓, 1,   MMP↓, 30,   NHE1↓, 1,   OATPs↓, 2,   TRPM7↓, 1,   ZO-1↑, 1,  

Immune & Inflammatory Signaling(tgid=16) ⓘ

CB2 / CNR2↑, 1,   CD4+↑, 1,   CD44↓, 2,   CD47↓, 1,   CD8+↑, 3,   COX1↓, 1,   COX1↑, 1,   COX2/PTGS2↓, 26,   CXCR4↓, 6,   DCells↑, 1,   HCAR2↑, 1,   HMGB1↓, 2,   ICAM-1↓, 1,   IFN-γ↓, 1,   IFN-γ↑, 1,   IL1↓, 2,   IL10↓, 2,   IL10↑, 1,   IL12↑, 1,   IL1β↓, 10,   IL2↓, 1,   IL2↑, 4,   IL6↓, 15,   IL8↓, 3,   Imm↑, 16,   Imm↝, 1,   INF-γ↑, 1,   INF-γ↝, 1,   Inflam↓, 19,   Inflam↑, 2,   M2 MC↓, 1,   MDSCs↓, 1,   Neut↑, 2,   NF-kB↓, 45,   NF-kB↑, 1,   p‑NF-kB↑, 1,   NK cell↑, 5,   NLRP3↓, 3,   NLRP3↑, 2,   p65↓, 2,   p‑p65↓, 1,   PD-1↓, 2,   PD-L1↓, 4,   PD-L1↑, 1,   PGE2↓, 7,   PGE2↑, 1,   PSA↓, 5,   T-Cell↑, 1,   Th1 response↑, 1,   Th2↑, 1,   TLR4↓, 1,   TNF-α↓, 18,   TNF-α↑, 2,  

Cellular Microenvironment(tgid=17) ⓘ

TAMS↓, 1,  

Synaptic & Neurotransmission(tgid=18) ⓘ

BDNF↓, 1,   TrkB↓, 1,  

Protein Aggregation(tgid=19) ⓘ

PSEN1/PS1↓, 1,  

Hormonal & Nuclear Receptors(tgid=20) ⓘ

AR↓, 2,   CYP19↓, 1,   ER-α36↓, 1,   PPARγ↑, 1,  

Drug Metabolism & Resistance(tgid=21) ⓘ

ABCG2↓, 1,   BioAv↓, 14,   BioAv↑, 18,   BioAv↝, 4,   chemoR↓, 1,   ChemoSen?, 1,   ChemoSen↑, 106,   ChemoSen⇅, 1,   ChemoSen↝, 1,   ChemoSen∅, 2,   CompStab↓, 2,   CYP1A1↓, 3,   CYP1A1↑, 1,   CYP1A2↓, 1,   CYP3A4↓, 1,   Dose?, 2,   Dose↑, 9,   Dose↝, 43,   Dose∅, 1,   eff↓, 8,   eff↑, 32,   eff⇅, 1,   eff↝, 9,   eff∅, 1,   Half-Life↓, 3,   Half-Life↑, 1,   Half-Life↝, 6,   MDR1↓, 4,   MRP1/ABCC1↓, 2,   P-gp/ABCB1↓, 6,   P450↓, 3,   RadioS↑, 23,   RadioS↝, 1,   selectivity↑, 38,   Synergy↑, 33,  

Clinical Biomarkers(tgid=22) ⓘ

AFP↓, 1,   ALAT↓, 4,   ALP↓, 1,   AR↓, 2,   AST↓, 2,   Bil↝, 1,   BUN↓, 3,   CEA↓, 1,   creat↓, 3,   EGFR↓, 8,   EGFR↑, 1,   p‑EGFR↓, 1,   EZH2↓, 1,   HemoG↑, 1,   HER2/EBBR2↓, 1,   IL6↓, 15,   LDH↑, 1,   e-LDH↑, 1,   Myc↑, 1,   NSE↓, 1,   PC↑, 1,   PD-L1↓, 4,   PD-L1↑, 1,   PSA↓, 5,   RBC↑, 3,   Verbal↑, 1,   WBC↑, 2,  

Functional Outcomes(tgid=23) ⓘ

AntiAge↑, 1,   AntiCan↓, 1,   AntiCan↑, 23,   AntiCan∅, 1,   AntiDiabetic↑, 1,   antiNeop↑, 1,   AntiTum↑, 12,   Appetite↑, 2,   BowelM↑, 1,   breath↑, 1,   cachexia↓, 2,   cardioP↑, 10,   chemoP?, 1,   chemoP↓, 3,   chemoP↑, 181,   chemoP↝, 1,   chemoP∅, 1,   chemoPv↑, 5,   ChemoSideEff↓, 4,   cognitive↑, 2,   fatigue↓, 1,   fatigue∅, 1,   hepatoP↑, 17,   hepatoP∅, 1,   memory↑, 1,   Mucositis↓, 1,   Nausea↓, 1,   neuroP↓, 1,   neuroP↑, 7,   NP/CIPN↓, 3,   OS↓, 2,   OS↑, 12,   OS⇅, 1,   Pain↓, 7,   PFS↑, 1,   QoL↑, 20,   QoL∅, 2,   radioP↑, 29,   radioP↝, 1,   Remission↑, 1,   RenoP↑, 9,   RenoP∅, 1,   Risk↓, 19,   Risk↑, 2,   Risk⇅, 1,   Sleep↑, 2,   Strength↑, 2,   toxicity↓, 11,   toxicity↑, 1,   toxicity↝, 4,   toxicity∅, 2,   TumVol?, 1,   TumVol↓, 10,   TumVol↑, 1,   TumW↓, 1,   Weight↑, 5,   Weight∅, 1,  

Infection & Microbiome(tgid=24) ⓘ

AntiBio↓, 1,   GutMicro↑, 4,   Sepsis↓, 2,  

Ingredients & Constituents(tgid=25) ⓘ

Ingr↝, 1,  
Total Targets: 608

Pathway results for Effect on Normal Cells:


Redox & Oxidative Stress(tgid=1) ⓘ

antiOx↓, 4,   antiOx↑, 60,   ARE↑, 1,   Catalase↑, 24,   Copper↓, 1,   Fenton↓, 2,   GPx↑, 23,   GPx1↑, 1,   GPx4↓, 1,   GPx4↑, 1,   GSH↑, 28,   GSR↑, 4,   GSTs↑, 9,   H2O2↓, 1,   HDL↑, 2,   HO-1↓, 2,   HO-1↑, 21,   Iron↓, 2,   Iron↑, 1,   Keap1↓, 2,   Keap1↝, 1,   lipid-P↓, 18,   MDA↓, 18,   MDA↑, 1,   MPO↓, 6,   MPO↑, 2,   NADH↓, 1,   NOX↓, 1,   NOX4↓, 2,   NQO1↑, 3,   NRF2↑, 39,   RNS↓, 3,   ROS↓, 67,   ROS↝, 1,   ROS∅, 2,   mt-ROS?, 1,   SAM-e↑, 1,   selenoP↑, 2,   SOD↑, 34,   SOD1↑, 3,   SOD2↑, 2,   TAC↑, 1,   TBARS↓, 2,   VitE↓, 1,  

Metal & Cofactor Biology(tgid=2) ⓘ

IronCh↑, 1,  

Mitochondria & Bioenergetics(tgid=3) ⓘ

compI↑, 1,   compII↑, 1,   compIII↑, 1,   DRP1/DNM1L↓, 1,   FIS1↓, 1,   Insulin↓, 1,   Insulin↑, 1,   MFN2↑, 2,   mtDam↓, 1,   PGC-1α↑, 2,   PGC-1α↝, 1,   PINK1↑, 1,   SIRT3↑, 2,  

Core Metabolism/Glycolysis(tgid=4) ⓘ

15-LOX/ALOX15↓, 1,   5LO↓, 1,   ACC↓, 1,   Acetyl-CoA↓, 1,   adiP↑, 1,   ALAT↓, 9,   AMPK↑, 5,   ATP↑, 4,   ATP↝, 1,   CRM↓, 1,   FABP4↓, 1,   FASN↓, 1,   FFA/NEFA↓, 1,   glucose↓, 4,   glucose↝, 1,   GlucoseCon↑, 1,   GSK‐3β↑, 1,   H2S↑, 1,   KeyT↝, 1,   LDL↓, 4,   NAD↝, 1,   NADPH↓, 4,   NADPH↑, 1,   PLA2↓, 1,   SIRT1↑, 4,   SREBF2⇅, 1,  

Cell Death(tgid=5) ⓘ

AIF↓, 1,   Apoptosis↓, 10,   ASK1↓, 1,   BAX↓, 1,   Bax:Bcl2↓, 1,   Bcl-2↑, 2,   Bcl-xL↑, 1,   Casp12↓, 1,   Casp3↓, 12,   cl‑Casp8↑, 1,   Casp9↓, 5,   Cyt‑c↓, 1,   Fas↓, 1,   FasL↓, 1,   Ferroptosis↓, 2,   GranB/GZMB↓, 1,   iNOS↓, 8,   necrosis↓, 1,   p38↓, 2,   p‑p38↓, 1,   TUNEL↓, 1,  

Kinase & Signal Transduction(tgid=6) ⓘ

Akt↓, 2,   Akt↑, 5,   Akt↝, 1,   AMPKα↑, 1,   ERK↓, 2,   IGF-1R↓, 1,   IKKα↑, 1,   IκB?, 1,   JAK↓, 1,   JAK2↑, 1,   JNK↓, 1,   p‑JNK↓, 2,   MAPK↓, 2,   MAPK↑, 1,   MAPK↝, 1,   mTOR↓, 3,   p‑mTOR↓, 1,   PDGFR-BB↓, 1,   PI3K↓, 2,   PI3K↑, 2,   PKCδ?, 1,   PKCδ↓, 1,   PTEN↓, 1,   STAT3↓, 1,   STAT3↑, 1,   STAT3↝, 1,  

Transcription & Epigenetics(tgid=7) ⓘ

AntiThr↑, 4,   ATF2↑, 1,   ATF4↓, 1,   FOXO3↑, 1,   HDAC↑, 1,   miR-34a↓, 1,   other?, 2,   other↓, 5,   other↑, 10,   other↝, 2,   tumCV↓, 1,  

Protein Folding & ER Stress(tgid=8) ⓘ

CHOP/DDIT3↓, 2,   p‑eIF2α↓, 1,   ER Stress↓, 3,   GRP78/BiP↓, 2,   XBP-1↓, 1,  

Autophagy & Lysosomes(tgid=9) ⓘ

Beclin-1/ATG6↑, 1,   LC3‑Ⅱ/LC3‑Ⅰ↑, 1,   LC3II↑, 1,   MitoP↓, 1,   p62↑, 1,   PARK2↑, 1,  

DNA Damage & Repair(tgid=10) ⓘ

DNAdam↓, 4,   DNArepair↑, 1,   P53↓, 3,   P53↑, 1,   PARP1↓, 1,   PCNA↑, 1,   SIRT6↑, 1,   Telomerase↓, 1,   TOP1↓, 1,  

Cell Cycle & Senescence(tgid=11) ⓘ

E2Fs↑, 1,   GADD45A↑, 1,   P21↓, 1,  

Proliferation, Differentiation & Cell State(tgid=12) ⓘ

BMPs↑, 1,   CEBPA↓, 1,   EP2↓, 1,   HH↓, 1,   IGF-1↑, 1,   mTORC1↓, 1,   neuroG↑, 1,   p300↓, 1,   TumCP↓, 1,  

Migration(tgid=13) ⓘ

AntiAg↓, 2,   AntiAg↑, 5,   AP-1↓, 3,   Ca+2↓, 1,   Ca+2↝, 2,   Cartilage↑, 1,   COL1↓, 1,   E-cadherin↑, 1,   EMT↓, 1,   MMP13↓, 1,   MMP2↓, 1,   MMPs↓, 1,   p‑Rac1↓, 1,   serineP↓, 1,   TGF-β↓, 1,   TGF-β↑, 2,   TGF-β1↓, 1,   TIMP1↓, 1,   TumCI↓, 1,   TumCMig↓, 1,   uPA↑, 1,   Vim↓, 1,   α-SMA↓, 1,   α-SMA↝, 1,  

Angiogenesis & Vasculature(tgid=14) ⓘ

angioG↓, 1,   Hif1a↑, 1,   NO↓, 5,   VCAM-1↓, 2,  

Barriers & Transport(tgid=15) ⓘ

BBB↑, 5,   BBB∅, 1,   GastroP↑, 1,   GLUT4↑, 1,   H+/K+-ATPase↓, 1,   IBI↑, 1,   memfluid↑, 1,   MMP↑, 5,   TRPM7↓, 1,  

Immune & Inflammatory Signaling(tgid=16) ⓘ

CD25+↑, 1,   CD4+↑, 2,   CD8+↑, 1,   COX1↓, 3,   COX2/PTGS2↓, 15,   COX2/PTGS2↑, 1,   FOXP3↑, 1,   HMGB1↓, 2,   IFN-γ↓, 2,   IL10↓, 4,   IL10↑, 5,   IL17↓, 1,   IL18↓, 1,   IL1β↓, 13,   IL2↓, 1,   IL4↓, 3,   IL4↑, 2,   IL6↓, 23,   IL8↓, 2,   Imm↑, 6,   Imm↝, 1,   Inflam↓, 64,   LPS↓, 2,   M2 MC↑, 2,   pol-M2 MC↑, 1,   MCP1/CCL2↓, 3,   MyD88↓, 1,   NF-kB↓, 20,   NLRP3↓, 4,   PGE2↓, 7,   TLR4↓, 3,   TNF-α↓, 27,   Treg lymp↝, 1,   TRIF↓, 1,   VitD↑, 1,  

Synaptic & Neurotransmission(tgid=18) ⓘ

5HT↓, 1,   5HT↑, 1,   AChE↓, 4,   BChE↓, 2,   BDNF↑, 2,   MAOA↓, 1,   MAOB↓, 1,   NGF↑, 1,   TrkB↑, 1,   β-Endo↑, 1,  

Protein Aggregation(tgid=19) ⓘ

APP↓, 1,   Aβ↓, 2,   BACE/β-secretase↓, 1,   p‑tau↓, 1,  

Hormonal & Nuclear Receptors(tgid=20) ⓘ

ACE/ACE1↓, 1,   ACE2↓, 1,   BNP↓, 1,   NR1H4↑, 1,   PPARγ↓, 1,   testos↑, 2,  

Drug Metabolism & Resistance(tgid=21) ⓘ

BioAv↓, 19,   BioAv↑, 21,   BioAv↝, 14,   BioEnh↑, 2,   ChemoSen↑, 1,   CYP3A2↓, 1,   Dose?, 3,   Dose↓, 2,   Dose↑, 2,   Dose↝, 14,   eff↑, 9,   GSTA1↑, 2,   Half-Life↓, 3,   Half-Life↑, 1,   Half-Life↝, 8,   P-gp/ABCB1↓, 2,   selectivity↑, 3,   Synergy↑, 7,  

Clinical Biomarkers(tgid=22) ⓘ

ALAT↓, 9,   ALB↝, 1,   ALP↓, 3,   AST↓, 12,   BloodF↑, 1,   BMD↑, 3,   BP↓, 4,   BUN?, 1,   BUN↓, 4,   Calcium↑, 1,   creat↓, 9,   hs-CRP↓, 1,   IL6↓, 23,   IRes↝, 1,   KeyT↝, 1,   LDH↓, 4,   Mag↑, 1,   NOS2↓, 1,   SpO2↑, 1,   TC↓, 1,   TG/TAG↓, 1,   TMAO↓, 1,   Urea↓, 2,   VitD↑, 1,  

Functional Outcomes(tgid=23) ⓘ

Analgesic↑, 1,   AntiAge↑, 5,   antiAll↑, 8,   AntiArt↑, 1,   AntiCan↑, 10,   AntiDiabetic↓, 1,   AntiDiabetic↑, 11,   antiPs↑, 2,   AntiTum↓, 1,   AntiTum↑, 3,   cardioP?, 2,   cardioP↑, 25,   chemoP↑, 46,   chemoPv↑, 3,   ChemoSideEff↓, 1,   cognitive↓, 1,   cognitive↑, 11,   cough?, 1,   hepatoP↓, 1,   hepatoP↑, 25,   memory↑, 5,   motorD↑, 1,   Mucositis↓, 1,   neuroP↓, 1,   neuroP↑, 28,   Obesity↓, 8,   OS↑, 4,   Pain↓, 4,   QoL↑, 1,   radioP↑, 8,   RenoP↑, 15,   Risk↓, 1,   SoreThr?, 1,   Strength↑, 1,   Stress↓, 1,   Stroke↓, 5,   toxicity↓, 24,   toxicity↑, 1,   toxicity↝, 9,   toxicity∅, 1,   Weight↓, 1,   Weight↑, 1,   Wound Healing↑, 1,  

Infection & Microbiome(tgid=24) ⓘ

AntiBio↑, 4,   AntiFungal↑, 3,   AntiViral↑, 5,   Bacteria↓, 8,   Diar↓, 1,   GutMicro↑, 9,   Sepsis↓, 3,  

Ingredients & Constituents(tgid=25) ⓘ

Ingr↑, 2,   Ingr↝, 2,  
Total Targets: 360

Scientific Paper Hit Count for: chemoP, ChemoProtective
21 Chemotherapy
14 Cisplatin
11 Silymarin (Milk Thistle) silibinin
10 Hydrogen Gas
9 Selenium
8 doxorubicin
8 Selenite (Sodium)
7 Curcumin
7 Thymoquinone
6 Melatonin
5 Allicin (mainly Garlic)
5 Anti-oxidants
5 Radiotherapy/Radiation
5 phytic acid, Inositol hexakisphosphate
4 Astragalus
4 Quercetin
4 Fucoidan
4 Honokiol
4 Inositol
4 Licorice
4 Luteolin
4 Lycopene
4 Morin
3 Ashwagandha(Withaferin A)
3 Astaxanthin
3 Paclitaxel/Taxol
3 Coenzyme Q10
3 EGCG (Epigallocatechin Gallate)
3 diet Short Term Fasting
3 Dandelion Root
3 HydroxyTyrosol
3 isoorientin
3 Licochalcone A
3 low dose naltrexone
3 Linalool
3 Magnetic Fields
3 Urolithin
2 Alpha-Lipoic-Acid
2 Apigenin (mainly Parsley)
2 beta-glucans
2 Brucea javanica
2 brusatol
2 Boron
2 Butyrate
2 Propolis -bee glue
2 Carvacrol
2 Thymol-Thymus vulgaris
2 Chrysin
2 Garcinol
2 Docosahexaenoic Acid
2 Ellagic acid
2 Fisetin
2 Flaxseed/Linseed
2 Shilajit/Fulvic Acid
2 iodine
2 5-fluorouracil
2 Metformin
2 Oleuropein
2 Rosmarinic acid
2 Rutin
2 Selenium NanoParticles
1 Silver-NanoParticles
1 Anzaroot, Astragalus fasciculifolius Bioss
1 Anethole/trans-Anethole
1 Atorvastatin
1 immunotherapy
1 Baicalein
1 Berberine
1 Gold NanoParticles
1 Beta-Caryophyllene
1 Betulinic acid
1 Bromelain
1 α-Bisabolol / Chamomile oil
1 Carnosic acid
1 Caffeic Acid Phenethyl Ester (CAPE)
1 Cat’s Claw
1 Chlorogenic acid
1 Chlorophyllin
1 Chocolate
1 Vitamin E
1 Calorie Restriction Mimetics
1 HydroxyCitric Acid
1 Crocetin
1 diet Plant based
1 Diindolylmethane
1 Indole-3-carbinol
1 Lemongrass Extract/Citral
1 Disulfiram
1 Copper and Cu NanoParticles
1 Echinacea
1 Docetaxel
1 Emodin
1 Eugenol
1 Exercise
1 Formononetin
1 carboplatin
1 Gallic acid
1 Ginkgetin
1 γ-linolenic acid (Borage Oil)
1 Hyperoside
1 MCT, metronomic chemo
1 Isoliquiritigenin
1 isoflavones
1 isoquercitrin
1 Kaempferol
1 Lactoferrin/Talactoferrin
1 SDG/lignans
1 Magnolol
1 Matrine
1 Magnetic Field Rotating
1 Moringa oleifera
1 Methylsulfonylmethane
1 Naringin
1 Aidi injection
1 Phenylbutyrate
1 Phenethyl isothiocyanate
1 Piperine
1 Psoralidin
1 benzo(a)pyrene
1 buckwheat sprouts
1 irinotecan
1 Sulforaphane (mainly Broccoli)
1 Shikonin
1 Squalene
1 Vitexin
1 Isovitexin
1 Zerumbone
Query results interpretion may depend on "conditions" listed in the research papers.
Such Conditions may include : 
  -low or high Dose
  -format for product, such as nano of lipid formations
  -different cell line effects
  -synergies with other products 
  -if effect was for normal or cancerous cells

Filter Conditions: Pro/AntiFlg:%  IllCat:%  CanType:%  Cells:%  prod#:%  Target#:1171  State#:%  Dir#:%
  wNotes=0  sortOrder:rid,rpid

 

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