Aβ Cancer Research Results

Aβ, Aβ aggregation: Click to Expand ⟱
Source:
Type:
Beta-Amyloid (Aβ): In Alzheimer’s disease, Aβ peptides tend to misfold and aggregate into oligomers and fibrils.
Scientific Papers found: Click to Expand⟱
3732- RF,    Electromagnetic treatment to old Alzheimer's mice reverses β-amyloid deposition, modifies cerebral blood flow, and provides selected cognitive benefit
- in-vivo, AD, NA
*cognitive↑, *Aβ↓,
3733- RF,    Long-term electromagnetic field treatment enhances brain mitochondrial function of both Alzheimer's transgenic mice and normal mice: a mechanism for electromagnetic field-induced cognitive benefit?
- in-vivo, AD, NA
*Aβ↓, *cognitive↑, *mt-ROS↓, *ATP↑,
3738- RF,    Electromagnetic Field Stimulation Therapy for Alzheimer's Disease
- Review, AD, NA
*cognitive↑, *Aβ↓, *ROS↓, *memory↑, *Inflam∅,
3743- RF,    Repeated electromagnetic field stimulation lowers amyloid-β peptide levels in primary human mixed brain tissue cultures
- in-vitro, AD, NA
*Aβ↓, *toxicity∅, *APP∅,
3461- RF,    Electromagnetic Field Stimulation Therapy for Alzheimer’s Disease
- Review, AD, NA
*Aβ↓, *HSF1↑, *ROS↓, *Inflam↓, *cognitive↑, *memory↑, *eff↑,
3490- RF,    Multidimensional insights into the repeated electromagnetic field stimulation and biosystems interaction in aging and age-related diseases
- Review, AD, NA - Review, Park, NA
*OS↑, *memory↑, *cognitive↑, *memory↑, *Aβ↓, *eff↑, *HSF1↑, *HSP70/HSPA5↑,
3003- RosA,    Comprehensive Insights into Biological Roles of Rosmarinic Acid: Implications in Diabetes, Cancer and Neurodegenerative Diseases
- Review, Var, NA - Review, AD, NA - Review, Park, NA
*Inflam↓, *antiOx↑, *neuroP↑, *IL6↓, *IL1β↓, *NF-kB↓, *PGE2↓, *COX2↓, *MMP↑, *memory↑, *ROS↓, *Aβ↓, *HMGB1↓, TumCG↓, MARK4↓, Zeb1↓, MDM2↓, BNIP3↑, ASC↑, NLRP3↓, PI3K↓, Akt↓, Casp1↓, E-cadherin↑, STAT3↓, TLR4↓, MMP↓, ICAM-1↓, AMPK↓, IL6↑, MMP2↓, Warburg↓, Bcl-xL↓, Bcl-2↓, TumCCA↑, EMT↓, TumMeta↓, mTOR↓, HSP27↓, Casp3↑, GlucoseCon↓, lactateProd↓, VEGF↓, p‑p65↓, GIT1↓, FOXM1↓, cycD1/CCND1↓, CDK4↓, MMP9↓, HDAC2↓,
3028- RosA,    Network pharmacology mechanism of Rosmarinus officinalis L.(Rosemary) to improve cell viability and reduces apoptosis in treating Alzheimer’s disease
- in-vitro, AD, HT22 - in-vivo, NA, NA
*Aβ↓, *Apoptosis↓, *antiOx↑, *neuroP↑, *eff↑, *IGF-1↑, *MMP9↑, *Src↓, *MAPK↓, *MMP↑,
3616- RosA,    Therapeutic effects of rosemary (Rosmarinus officinalis L.) and its active constituents on nervous system disorders
- Review, AD, NA
*Inflam↓, *memory↑, *toxicity↓, *ROS↓, *Catalase↑, *SOD↑, *NRF2↑, *Aβ↓, *AChE↓, *Ca+2↓, *NO↓, *IL2↓, *COX2↓, *PGE2↓, *MMPs↓, *TNF-α↓, *iNOS↓, *TLR4↓, *cognitive↑, *cortisol↓, *lipid-P↓,
3619- RosA,    Rosmarinic acid suppresses Alzheimer’s disease development by reducing amyloid β aggregation by increasing monoamine secretion
- Review, AD, NA
*BioAv↓, *BBB↝, *monoA↑, *TGF-β↓, *Aβ↓,
3620- RosA,    Rosmarinus officinalis and Methylphenidate Exposure Improves Cognition and Depression and Regulates Anxiety-Like Behavior in AlCl3-Induced Mouse Model of Alzheimer's Disease
- in-vivo, AD, NA
*antiOx↑, *Inflam↓, *memory↑, *Aβ∅, *GutMicro↑,
3937- RT,    Rutin prevents tau pathology and neuroinflammation in a mouse model of Alzheimer’s disease
- in-vivo, AD, NA
*p‑tau↓, *Inflam↓, *NF-kB↓, *cognitive↑, *Aβ↓, *memory↑, *neuroP↑, *BioAv↓, *BBB↑,
3936- RT,    Rutin improves spatial memory in Alzheimer's disease transgenic mice by reducing Aβ oligomer level and attenuating oxidative stress and neuroinflammation
- in-vivo, AD, NA
*memory↑, *Aβ↓, *SOD↑, *GSH↑, *GSSG↓, *MDA↓, *IL1β↓, *IL6↓, *antiOx↑, *Inflam↓,
3935- RT,    Sodium rutin ameliorates Alzheimer's disease-like pathology by enhancing microglial amyloid-β clearance
- in-vivo, AD, NA
*Aβ↓, *Glycolysis↓, *OXPHOS↑, *memory↑, *BioAv↓, *BioAv↑, *cognitive↑, *Inflam↓,
3934- RT,    Rutin: A Potential Therapeutic Agent for Alzheimer Disease
- Review, AD, NA
*ROS↓, *Aβ↓, *neuroP↑, *memory↑, *GSH↑, *SOD↑, *lipid-P↓, *MDA↓, *IL1β↓, *IL6↓, *cognitive↑, *BBB↑, *MAPK↑, *IL8↓, *COX2↓, *NF-kB↓, *iNOS↓,
3932- RT,    Rutin as a Natural Therapy for Alzheimer's Disease: Insights into its Mechanisms of Action
- Review, AD, NA
*cognitive↑, *BBB↑, *Aβ↓, *ROS↓, *Inflam↓,
4217- Sage,  RosA,  Aroma,    Neuroprotective Potential of Aromatic Herbs: Rosemary, Sage, and Lavender
- Review, AD, NA - Review, Park, NA
*Inflam↓, *antiOx↑, *neuroP↑, *ERK↑, *CREB↑, *BDNF↑, *Aβ↑, *AChE↓, *memory↑, *cognitive↑,
4114- SAMe,    S-Adenosylmethionine (SAMe) for Neuropsychiatric Disorders: A Clinician-Oriented Review of Research
- Review, AD, NA
*Mood↑, *BBB↑, *5HT↑, *p‑tau↓, *Aβ↓, *other↑,
4608- SeNPs,    Selenium Nanoparticles for Biomedical Applications: From Development and Characterization to Therapeutics
- Review, Var, NA - NA, AD, NA
*toxicity↝, *toxicity↓, *other↝, ROS↑, *Dose↝, *selenoP↑, AntiCan↑, AntiTum↑, *Bacteria↓, *radioP↑, *BioAv↑, *Inflam↓, *Imm↑, ChemoSen↑, *AntiAg↑, selectivity↑, eff↑, other↝, *eff↑, *Aβ↓, *eff↑,
4190- Sesame,    Sesame Seeds: A Nutrient-Rich Superfood
- Review, NA, NA
*antiOx↑, *LDL↓, *Aβ↓, *TNF-α↓, *SOD↑, *SIRT1↑, *Catalase↑, *GSH↑, *MDA↓, *GSTs↑, *IL4↑, *GPx↑, *COX2↓, *PGE2↓, *NO↓, CDK2↑, COX2↑, MMP9↑, ICAM-1↓, *BDNF↑, *PPARγ↑, *AChE↓, *Inflam↓, *HO-1↑, *NF-kB↓, *ROS↓,
3663- SFN,    Efficacy of Sulforaphane in Neurodegenerative Diseases
- Review, AD, NA - Review, Park, NA
*antiOx↑, *Inflam↓, *Half-Life↝, *NRF2↑, *NQO1↑, *HO-1↑, *TrxR↑, *ROS↓, *TNF-α↓, *IL1β↓, *IL6↓, *iNOS↓, *COX2↓, *Aβ↓, *GSH↑, *cognitive↑, *BACE↓, *HSP70/HSPA5↑, *neuroP↑, *ROS↓, *BBB↑, *MMP9↓,
3664- SFN,    Sulforaphane Upregulates the Heat Shock Protein Co-Chaperone CHIP and Clears Amyloid-β and Tau in a Mouse Model of Alzheimer's Disease
- in-vivo, AD, NA
*CHIP↑, *HSP70/HSPA5↑, *Aβ↓, *tau↓,
3662- SFN,    Sulforaphane Inhibits the Generation of Amyloid-β Oligomer and Promotes Spatial Learning and Memory in Alzheimer's Disease (PS1V97L) Transgenic Mice
- in-vivo, AD, NA
*Aβ↓, *cognitive↑,
3661- SFN,    Beneficial Effects of Sulforaphane Treatment in Alzheimer's Disease May Be Mediated through Reduced HDAC1/3 and Increased P75NTR Expression
- in-vitro, AD, NA
*cognitive↑, *HDAC1↓, *HDAC2↓, *HDAC3↓, *H3↑, *H4↑, *Aβ↓, *BioAv↑, *BBB↑, *neuroP↑,
3658- SFN,    Pre-Clinical Neuroprotective Evidences and Plausible Mechanisms of Sulforaphane in Alzheimer’s Disease
- Review, AD, NA
*NRF2↑, *antiOx↑, *neuroP↑, *Aβ↓, *BACE↓, *NQO1↑, *IL1β↓, *TNF-α↓, *IL6↓, *COX2↓, *iNOS↓, *NF-kB↓, *NLRP3↓, *Ca+2↓, *GSH↑, *MDA↓, *ROS↓, *SOD↑, *HO-1↑, *TrxR↑, *cognitive↑, *tau↓, *HSP70/HSPA5↑,
3321- SIL,    Silymarin (Milk thistle)
- Review, AD, NA
*neuroP↝, *Dose↝, *Half-Life?, *BioAv↝, *cognitive↑, *Aβ↓, *Inflam↓, *OS↑, *memory↑,
3320- SIL,    Neuroprotective Potential of Silymarin against CNS Disorders: Insight into the Pathways and Molecular Mechanisms of Action
- Review, AD, NA
*hepatoP↑, *neuroP↑, *ROS↓, *β-Amyloid↓, *Inflam↓, *Aβ↓, *NF-kB↓, *TNF-α↓, *TNF-β↓, *iNOS↓, *NO↓, *COX2↓,
3319- SIL,    Silymarin and neurodegenerative diseases: Therapeutic potential and basic molecular mechanisms
- Review, AD, NA - Review, Park, NA - Review, Stroke, NA
*neuroP↑, *ROS↓, *Inflam↓, *Apoptosis↓, *BBB?, *tau↓, *NF-kB↓, *IL1β↓, *TNF-α↓, *IL4↓, *MAPK↓, *memory↑, *cognitive↑, *Aβ↓, *ROS↓, *lipid-P↓, *GSH↑, *MDA↓, *SOD↑, *Catalase↑, *AChE↓, *BChE↓, *p‑ERK↓, *p‑JNK↓, *p‑p38↓, *GutMicro↑, *COX2↓, *iNOS↓, *TLR4↓, *neuroP↑, *Strength↑, *AMPK↑, *MMP↑, *necrosis↓, *NRF2↑, *HO-1↑,
3650- SIL,    Silibinin: a novel inhibitor of Aβ aggregation
- in-vitro, AD, SH-SY5Y
*Aβ↓, *H2O2↓,
4123- Silicon,    The potential influence of silica present in drinking water on Alzheimer's disease and associated disorders
- Review, AD, NA
*Aβ↓, *cognitive↝,
4891- Sper,    Spermidine as a promising anticancer agent: Recent advances and newer insights on its molecular mechanisms
- Review, Var, NA - Review, AD, NA
TumCCA↑, TumCP↓, TumCG↓, *Inflam↓, *antiOx↑, *neuroP↑, *cognitive↑, *Aβ↓, *mitResp↑, AntiCan↑, TumCD↑, TumAuto↑, *AntiAge↑, LC3B-II↑, ATG5↑, Beclin-1↑, mt-ROS↑, H2O2↑, Apoptosis↑, *ROS↑, ChemoSen↑, MMP↓, Cyt‑c↑,
3959- Taur,    Taurine Directly Binds to Oligomeric Amyloid-β and Recovers Cognitive Deficits in Alzheimer Model Mice
- in-vivo, AD, NA
*cognitive↑, *Aβ∅, *other↑,
3958- Taur,    Evaluation of the neuroprotective effect of taurine in Alzheimer’s disease using functional molecular imaging
- in-vivo, AD, NA
*neuroP↑, *Aβ∅, *cognitive↑, *toxicity↓, *Ca+2↓, *memory↑,
3555- TQ,    Thymoquinone administration ameliorates Alzheimer's disease-like phenotype by promoting cell survival in the hippocampus of amyloid beta1-42 infused rat model
- in-vivo, AD, NA
*memory↑, *BAX↓, *Aβ↓, *p‑tau↓, *AChE↓, *p‑Akt↓, *Ach↑, *Inflam↓,
3556- TQ,    Thymoquinone alleviates the experimentally induced Alzheimer’s disease inflammation by modulation of TLRs signaling
- in-vivo, AD, NA
*Inflam↓, *memory↑, *cognitive↑, *Aβ↓, *TNF-α↓, *IL1β↓, *TLR2↓, *NF-kB↓, *IRF3↓, TLR4↓, MyD88↓, TRIF↓,
3557- TQ,    Thymoquinone protects against lipopolysaccharides-induced neurodegeneration and Alzheimer-like model in mice.
- in-vivo, AD, NA
*Inflam↓, *antiOx↑, *cognitive↑, *TNF-α↓, *IL1β↓, *AChE↓, *IL10↑, *ChAT↑, *Aβ↓,
3559- TQ,    Molecular signaling pathway targeted therapeutic potential of thymoquinone in Alzheimer’s disease
- Review, AD, NA - Review, Var, NA
*antiOx↑, *Inflam↓, *AChE↓, AntiCan↑, *cardioP↑, *RenoP↑, *neuroP↑, *hepatoP↑, TumCG↓, Apoptosis↑, PI3K↓, Akt↑, TumCCA↑, angioG↓, *NF-kB↓, *TLR2↓, *TLR4↓, *MyD88↓, *TRIF↓, *IRF3↓, *IL1β↓, *IL6↓, *IL12↓, *NRF2↑, *COX2↓, *VEGF↓, *MMP9↓, *cMyc↓, *cycD1/CCND1↓, *TumCP↓, *TumCI↓, *MDA↓, *TGF-β↓, *CRP↓, *Casp3↓, *GSH↑, *IL10↑, *iNOS↑, *lipid-P↓, *SOD↑, *H2O2↓, *ROS↓, *LDH↓, *Catalase↑, *GPx↑, *AChE↓, *cognitive↑, *MAPK↑, *JNK↑, *BAX↓, *memory↑, *Aβ↓, *MMP↑,
3564- TQ,    The Potential Neuroprotective Effect of Thymoquinone on Scopolamine-Induced In Vivo Alzheimer's Disease-like Condition: Mechanistic Insights
- in-vivo, AD, NA
*Inflam↓, *AntiCan↑, *antiOx↑, *neuroP↑, *cognitive↑, *Aβ↓, *PPARγ↑, *NF-kB↓, *p‑tau↓, *MMP↑, *memory↑, *NF-kB↓, *ROS↓,
3565- TQ,    Thymoquinone as a potential therapeutic for Alzheimer’s disease in transgenic Drosophila melanogaster model
*cognitive↑, *ROS↓, *SOD↑, *AChE↝, *Aβ↓,
3570- TQ,    Thymoquinone alleviates the experimentally induced Alzheimer's disease inflammation by modulation of TLRs signaling
- in-vivo, AD, NA
*Inflam↓, *Aβ↓, *TNF-α↓, *IL1β↓, *TLR2↓, *IRF3↓, *TLR4↓, *memory↑, *NF-kB↓, *MyD88↓, *TRIF↓, *BBB↑, *cognitive↑,
3571- TQ,    The Role of Thymoquinone in Inflammatory Response in Chronic Diseases
- Review, Var, NA - Review, Stroke, NA
*BioAv↓, *BioAv↑, *Inflam↓, *antiOx↑, *ROS↓, *GSH↑, *GSTs↑, *MPO↓, *NF-kB↓, *COX2↓, *IL1β↓, *TNF-α↓, *IFN-γ↓, *IL6↓, *cardioP↑, *lipid-P↓, *TAC↑, *RenoP↑, Apoptosis↑, TumCCA↑, TumCP↓, TumCMig↓, angioG↓, TNF-α↓, NF-kB↓, ROS↑, EMT↓, *Aβ↓, *p‑tau↓, *BACE↓, *TLR2↓, *TLR4↓, *MyD88↓, *IRF3↓, *eff↑, eff↑, DNAdam↑, *iNOS↓,
3788- UA,  RosA,    Ursolic acid and rosmarinic acid ameliorate alterations in hippocampal neurogenesis and social memory induced by amyloid beta in mouse model of Alzheimer’s disease
- in-vivo, AD, NA
*neuroP↑, *Aβ↓, *p‑tau↓, *memory↑, *Inflam↓, *ROS↓,
4869- Uro,    Urolithin A in Central Nervous System Disorders: Therapeutic Applications and Challenges
- Review, AD, NA - Review, Park, NA - Review, Stroke, NA
*MitoP↑, *Inflam↓, *antiOx↑, *Risk↓, *Aβ↓, *p‑tau↓, *p62↓, *PARK2↑, *MMP↑, *ROS↓, *Strength↑, *CRP↓, *IL1β↓, *IL6↓, *TNF-α↓, *AMPK↑, *NF-kB↓, *MAPK↓, *p62↑, *NRF2↑, *SOD↑, *Catalase↑, *HO-1↑, *Ferroptosis↓, *lipid-P↓, *Cartilage↑, *PI3K↓, *Akt↓, *mTOR↓, *Apoptosis↓, *neuroP↑, *Bcl-2↓, *BAX↑, *Casp3↑, *ATP↑, *eff↑, *motorD↑, *NLRP3↓, *radioP↑, *BBB↑,
4868- Uro,    Urolithin A improves Alzheimer’s disease cognition and restores mitophagy and lysosomal functions
- in-vivo, AD, NA
*memory↑, *Aβ↓, *tau↓, *MitoP↑, *lysosome↑, *CTSZ↝,
4865- Uro,    Urolithin A suppresses high glucose-induced neuronal amyloidogenesis by modulating TGM2-dependent ER-mitochondria contacts and calcium homeostasis
- in-vitro, Diabetic, NA - in-vitro, AD, NA
*antiOx↑, *neuroP↑, *Ca+2↓, *Aβ↓, *BACE↓, *p‑tau↓, *cognitive↑,
4864- Uro,    Therapeutic Potential of Mitophagy-Inducing Microflora Metabolite, Urolithin A for Alzheimer's Disease
- Review, AD, NA
*neuroP↑, *Half-Life↝, *BBB↑, *toxicity↓, *Inflam↓, *Strength↑, *BACE↓, *Aβ↓, *MitoP↑, *SIRT1↑, *SIRT3↑, *AMPK↑, *PGC-1α↑, *mTOR↓, *PARK2↑, *Beclin-1↑, *ROS↓, *GutMicro↑, *Risk↓,
4863- Uro,    Urolithin A reduces amyloid-beta load and improves cognitive deficits uncorrelated with plaque burden in a mouse model of Alzheimer's disease
- in-vivo, AD, NA
*memory↑, *Aβ↓, *OS↑, *cognitive↑,
4862- Uro,    Neuroprotective effect of Urolithin A via downregulating VDAC1-mediated autophagy in Alzheimer's disease
- in-vivo, AD, NA - in-vitro, Nor, PC12
*cognitive↑, *p‑PI3K↓, *p‑Akt↓, *AMPK↑, *VDAC1↓, *neuroP↑, *PARK2↑, *PTEN↑, *LC3‑Ⅱ/LC3‑Ⅰ↑, *p62↓, *Aβ↓, *Apoptosis↓,
4861- Uro,    Urolithin A improves Alzheimer's disease cognition and restores mitophagy and lysosomal functions
- in-vivo, AD, NA
*memory↑, *Aβ↓, *toxicity↓, *BBB↑, *p‑tau↓, *eff↓, *IL1α↓, *MCP1↓, *MIP‑1α↓, *TNF-α↓, *IL2↓, *SIRT1↓, *DNAdam↓, *Dose↝, *Strength↑, *motorD↑, *CTSZ↓,
4870- Uro,    Urolithin A attenuates memory impairment and neuroinflammation in APP/PS1 mice
- in-vivo, AD, NA
*cognitive↑, *Apoptosis↓, *neuroP↑, *Aβ↓, *AMPK↑, *NF-kB↓, *MAPK↓, *BACE↑, *neuroG↑, *Inflam↓, *memory↑,

Showing Research Papers: 151 to 200 of 224
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* indicates research on normal cells as opposed to diseased cells
Total Research Paper Matches: 224

Pathway results for Effect on Cancer / Diseased Cells:


Redox & Oxidative Stress ⓘ

H2O2↑, 1,   ROS↑, 2,   mt-ROS↑, 1,  

Mitochondria & Bioenergetics ⓘ

MMP↓, 2,  

Core Metabolism/Glycolysis ⓘ

AMPK↓, 1,   GlucoseCon↓, 1,   lactateProd↓, 1,   Warburg↓, 1,  

Cell Death ⓘ

Akt↓, 1,   Akt↑, 1,   Apoptosis↑, 3,   Bcl-2↓, 1,   Bcl-xL↓, 1,   Casp1↓, 1,   Casp3↑, 1,   Cyt‑c↑, 1,   MDM2↓, 1,   TumCD↑, 1,  

Transcription & Epigenetics ⓘ

other↝, 1,  

Protein Folding & ER Stress ⓘ

HSP27↓, 1,  

Autophagy & Lysosomes ⓘ

ATG5↑, 1,   Beclin-1↑, 1,   BNIP3↑, 1,   LC3B-II↑, 1,   TumAuto↑, 1,  

DNA Damage & Repair ⓘ

DNAdam↑, 1,  

Cell Cycle & Senescence ⓘ

CDK2↑, 1,   CDK4↓, 1,   cycD1/CCND1↓, 1,   TumCCA↑, 4,  

Proliferation, Differentiation & Cell State ⓘ

EMT↓, 2,   FOXM1↓, 1,   HDAC2↓, 1,   mTOR↓, 1,   PI3K↓, 2,   STAT3↓, 1,   TumCG↓, 3,  

Migration ⓘ

E-cadherin↑, 1,   GIT1↓, 1,   MARK4↓, 1,   MMP2↓, 1,   MMP9↓, 1,   MMP9↑, 1,   TumCMig↓, 1,   TumCP↓, 2,   TumMeta↓, 1,   Zeb1↓, 1,  

Angiogenesis & Vasculature ⓘ

angioG↓, 2,   VEGF↓, 1,  

Immune & Inflammatory Signaling ⓘ

ASC↑, 1,   COX2↑, 1,   ICAM-1↓, 2,   IL6↑, 1,   MyD88↓, 1,   NF-kB↓, 1,   p‑p65↓, 1,   TLR4↓, 2,   TNF-α↓, 1,   TRIF↓, 1,  

Protein Aggregation ⓘ

NLRP3↓, 1,  

Drug Metabolism & Resistance ⓘ

ChemoSen↑, 2,   eff↑, 2,   selectivity↑, 1,  

Clinical Biomarkers ⓘ

FOXM1↓, 1,   IL6↑, 1,  

Functional Outcomes ⓘ

AntiCan↑, 3,   AntiTum↑, 1,  
Total Targets: 67

Pathway results for Effect on Normal Cells:


Redox & Oxidative Stress ⓘ

antiOx↑, 15,   Catalase↑, 5,   Ferroptosis↓, 1,   GPx↑, 2,   GSH↑, 8,   GSSG↓, 1,   GSTs↑, 2,   H2O2↓, 2,   HO-1↑, 5,   lipid-P↓, 6,   MDA↓, 6,   MPO↓, 1,   NQO1↑, 2,   NRF2↑, 6,   OXPHOS↑, 1,   PARK2↑, 3,   ROS↓, 20,   ROS↑, 1,   mt-ROS↓, 1,   selenoP↑, 1,   SIRT3↑, 1,   SOD↑, 9,   TAC↑, 1,   TrxR↑, 2,   VDAC1↓, 1,  

Mitochondria & Bioenergetics ⓘ

ATP↑, 2,   mitResp↑, 1,   MMP↑, 6,   PGC-1α↑, 1,  

Core Metabolism/Glycolysis ⓘ

AMPK↑, 5,   cMyc↓, 1,   CREB↑, 1,   Glycolysis↓, 1,   LDH↓, 1,   LDL↓, 1,   PPARγ↑, 2,   SIRT1↓, 1,   SIRT1↑, 2,  

Cell Death ⓘ

Akt↓, 1,   p‑Akt↓, 2,   Apoptosis↓, 5,   BAX↓, 2,   BAX↑, 1,   Bcl-2↓, 1,   Casp3↓, 1,   Casp3↑, 1,   Ferroptosis↓, 1,   iNOS↓, 7,   iNOS↑, 1,   JNK↑, 1,   p‑JNK↓, 1,   MAPK↓, 4,   MAPK↑, 2,   necrosis↓, 1,   p‑p38↓, 1,  

Transcription & Epigenetics ⓘ

Ach↑, 1,   H3↑, 1,   H4↑, 1,   other↑, 2,   other↝, 1,  

Protein Folding & ER Stress ⓘ

HSF1↑, 2,   HSP70/HSPA5↑, 4,  

Autophagy & Lysosomes ⓘ

Beclin-1↑, 1,   LC3‑Ⅱ/LC3‑Ⅰ↑, 1,   lysosome↑, 1,   MitoP↑, 3,   p62↓, 2,   p62↑, 1,  

DNA Damage & Repair ⓘ

DNAdam↓, 1,  

Cell Cycle & Senescence ⓘ

cycD1/CCND1↓, 1,  

Proliferation, Differentiation & Cell State ⓘ

CHIP↑, 1,   ERK↑, 1,   p‑ERK↓, 1,   HDAC1↓, 1,   HDAC2↓, 1,   HDAC3↓, 1,   IGF-1↑, 1,   mTOR↓, 2,   neuroG↑, 1,   PI3K↓, 1,   p‑PI3K↓, 1,   PTEN↑, 1,   Src↓, 1,  

Migration ⓘ

AntiAg↑, 1,   APP∅, 1,   Ca+2↓, 4,   Cartilage↑, 1,   MMP9↓, 2,   MMP9↑, 1,   MMPs↓, 1,   TGF-β↓, 2,   TumCI↓, 1,   TumCP↓, 1,  

Angiogenesis & Vasculature ⓘ

NO↓, 3,   VEGF↓, 1,  

Barriers & Transport ⓘ

BBB?, 1,   BBB↑, 10,   BBB↝, 1,  

Immune & Inflammatory Signaling ⓘ

COX2↓, 10,   CRP↓, 2,   CTSZ↓, 1,   CTSZ↝, 1,   HMGB1↓, 1,   IFN-γ↓, 1,   IL10↑, 2,   IL12↓, 1,   IL1α↓, 1,   IL1β↓, 12,   IL2↓, 2,   IL4↓, 1,   IL4↑, 1,   IL6↓, 8,   IL8↓, 1,   Imm↑, 1,   Inflam↓, 27,   Inflam∅, 1,   MCP1↓, 1,   MIP‑1α↓, 1,   MyD88↓, 3,   NF-kB↓, 15,   PGE2↓, 3,   TLR2↓, 4,   TLR4↓, 5,   TNF-α↓, 12,   TNF-β↓, 1,   TRIF↓, 2,  

Synaptic & Neurotransmission ⓘ

5HT↑, 1,   AChE↓, 8,   AChE↝, 1,   BChE↓, 1,   BDNF↑, 2,   ChAT↑, 1,   monoA↑, 1,   tau↓, 4,   p‑tau↓, 9,  

Protein Aggregation ⓘ

Aβ↓, 46,   Aβ↑, 1,   Aβ∅, 3,   BACE↓, 5,   BACE↑, 1,   NLRP3↓, 2,   β-Amyloid↓, 1,  

Hormonal & Nuclear Receptors ⓘ

cortisol↓, 1,  

Drug Metabolism & Resistance ⓘ

BioAv↓, 4,   BioAv↑, 4,   BioAv↝, 1,   Dose↝, 3,   eff↓, 1,   eff↑, 7,   Half-Life?, 1,   Half-Life↝, 2,  

Clinical Biomarkers ⓘ

CRP↓, 2,   GutMicro↑, 3,   IL6↓, 8,   LDH↓, 1,  

Functional Outcomes ⓘ

AntiAge↑, 1,   AntiCan↑, 1,   cardioP↑, 2,   cognitive↑, 30,   cognitive↝, 1,   hepatoP↑, 2,   memory↑, 25,   Mood↑, 1,   motorD↑, 2,   neuroP↑, 21,   neuroP↝, 1,   OS↑, 3,   radioP↑, 2,   RenoP↑, 2,   Risk↓, 2,   Strength↑, 4,   toxicity↓, 5,   toxicity↝, 1,   toxicity∅, 1,  

Infection & Microbiome ⓘ

Bacteria↓, 1,   IRF3↓, 4,  
Total Targets: 176

Scientific Paper Hit Count for: Aβ, Aβ aggregation
13 Urolithin
12 Curcumin
12 Magnetic Fields
11 Ferulic acid
9 Resveratrol
8 Berberine
8 Thymoquinone
7 Alpha-Lipoic-Acid
7 Rosmarinic acid
6 EGCG (Epigallocatechin Gallate)
6 Quercetin
6 EMF
5 Ashwagandha(Withaferin A)
5 Carnosine
5 Crocetin
5 Hydrogen Gas
5 Magnetic Field Rotating
5 Mushroom Lion’s Mane
5 Rutin
5 Sulforaphane (mainly Broccoli)
4 Apigenin (mainly Parsley)
4 Folic Acid, Vit B9
4 Ginseng
4 Silymarin (Milk Thistle) silibinin
4 Vitamin B1/Thiamine
3 beta-carotene(VitA)
3 Cinnamon
3 Honokiol
3 Luteolin
3 Radio Frequency
3 Vitamin B3,Niacin
3 Vitamin B5,Pantothenic Acid
3 Vitamin K2
2 Aromatherapy
2 Huperzine A/Huperzia serrata
2 Bacopa monnieri
2 borneol
2 Boron
2 Boswellia (frankincense)
2 Capsaicin
2 Vitamin E
2 diet Short Term Fasting
2 Ginkgo biloba
2 MCToil
2 Moringa oleifera
2 Taurine
2 Vitamin D3
1 Anthocyanins
1 Astaxanthin
1 Carnosic acid
1 Caffeic acid
1 Choline
1 Coenzyme Q10
1 Rivastigmine
1 Galantamine
1 Emodin
1 Phosphatidylserine
1 Fisetin
1 Flickering Light Stimulation
1 Exercise
1 Shilajit/Fulvic Acid
1 Iron
1 hydrogen sulfide
1 Lutein
1 Zeaxanthin
1 Lycopene
1 Methylsulfonylmethane
1 Piperine
1 Piperlongumine
1 Salvia officinalis
1 S-adenosyl-L-methionine
1 Selenium NanoParticles
1 Sesame seeds and Oil
1 Silicic Acid
1 Spermidine
1 Ursolic acid
1 Vitamin A, Retinoic Acid
1 Vitamin B12
1 Vitamin B2,Riboflavin
1 probiotics
Query results interpretion may depend on "conditions" listed in the research papers.
Such Conditions may include : 
  -low or high Dose
  -format for product, such as nano of lipid formations
  -different cell line effects
  -synergies with other products 
  -if effect was for normal or cancerous cells

Filter Conditions: Pro/AntiFlg:%  IllCat:%  CanType:%  Cells:%  prod#:%  Target#:1333  State#:%  Dir#:%
  wNotes=0  sortOrder:rid,rpid

 

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