IL6 Cancer Research Results

IL6, Interleukin-6: Click to Expand ⟱
Source: HalifaxProj(inhibit)
Type:
Interleukin-6 (IL-6) is a cytokine that plays a significant role in inflammation and the immune response. It is produced by various cell types, including T cells, B cells, macrophages, and fibroblasts.
IL-6 can promote tumor cell proliferation and survival. Many cancer cells produce IL-6, which can create an autocrine loop that supports their growth.
IL-6 is a high-value inflammatory biomarker in cancer, reporting cytokine burden, catabolic stress, and STAT3-linked survival signaling. While not tumor-specific, elevated and rising IL-6 strongly predicts poor prognosis and limited treatment tolerance, making it an important system-state indicator alongside CRP and ferritin.



Scientific Papers found: Click to Expand⟱
3201- EGCG,    Epigallocatechin Gallate (EGCG): Pharmacological Properties, Biological Activities and Therapeutic Potential
- Review, NA, NA
*AntiCan↑, *cardioP↑, *neuroP↑, *BioAv↝, *BioAv↓, *BioAv↓, *Dose↝, *Half-Life↝, *BioAv↑, *BBB↑, *hepatoP↓, *other↓, *Inflam↓, *NF-kB↓, *AP-1↓, *iNOS↓, *COX2↓, *ROS↓, *RNS↓, *IL8↓, *JAK↓, *PDGFR-BB↓, *IGF-1R↓, *MMP2↓, *P53↓, *NRF2↑, *TNF-α↓, *IL6↓, *E2Fs↑, *SOD1↑, *SOD2↑, Casp3↑, Cyt‑c↑, PARP↑, DNMTs↓, Telomerase↓, Hif1a↓, MMPs↓, BAX↑, Bak↑, Bcl-2↓, Bcl-xL↓, P53↑, PTEN↑, TumCP↓, MAPK↓, HGF/c-Met↓, TIMP1↑, HDAC↓, MMP9↓, uPA↓, GlutMet↓, ChemoSen↑, chemoP↑,
3594- EGCG,    Epigallocatechin-3-gallate inhibits secretion of TNF-alpha, IL-6 and IL-8 through the attenuation of ERK and NF-kappaB in HMC-1 cells
- in-vitro, AD, HMC1
*TNF-α↓, *IL6↓, *IL8↓, *Ca+2↓,
6784- EGCG,    Dietary (−)-Epigallocatechin Gallate (EGCG): State-of-the-Art Advances in Bioactivities, Bioavailability Enhancement Strategies, and Applications in Nutrition and Health
- Review, Nor, NA
*antiOx↑, *Inflam↓, *AntiCan↑, *cardioP↑, *neuroP↑, *GutMicro↑, *AntiBio↑, *ROS↓, *TNF-α↓, *IL6↓, TumCP↓, *LDL↓, *NO↓, *Obesity↓, *p‑tau↓, *Aβ↓, *NRF2↑, *SOD↑, *Catalase↑, *GPx↑, *NLRP3↓, *mTOR↓, TumCCA↑, NRF2↓, Apoptosis↑, SIRT1↓, miR-25-5p↓, PARP↑, Casp3↑, Casp9↑, ER Stress↑, TumAuto↑, EMT↓, TumCI↓, TumCMig↓, TGF-β↓, Smad1↓, STAT3↓, VEGF↓, angioG↓, Imm↑, EGFR↓, *GutMicro↑, *Bacteria↓, *AntiViral↑, *BioAv↓, *BioAv↑, *eff↑, *BioAv↑, eff↑, ChemoSen↑, *toxicity↝,
1976- EGCG,    Epigallocatechin-3-gallate exhibits anti-tumor effect by perturbing redox homeostasis, modulating the release of pro-inflammatory mediators and decreasing the invasiveness of glioblastoma cells
- in-vitro, GBM, U87MG
ROS↑, MMP↓, Casp3↑, Cyt‑c↑, Trx1↓, Ceru↓, IL6↓, IL8↓, MCP1/CCL2↓, RANTES?, uPA↝, ROS↑,
1503- EGCG,    Epigenetic targets of bioactive dietary components for cancer prevention and therapy
- Review, NA, NA
selectivity↑, DNMT1↓, RECK↑, MMPs↓, TumCI↓, angioG↓, TumMeta↓, HATs↓, IκB↑, NF-kB↓, IL6↓, COX2↓, NOS2↓, ac‑H3↑, ac‑H4↑, eff↑,
6814- EMD,    Emodin: A Review of its Pharmacology, Toxicity and Pharmacokinetics
- Review, Nor, NA
AntiCan↑, *hepatoP↑, *Inflam↑, *antiOx↑, *AntiBio↑, *BioAv↓, *AntiViral↑, *AntiDiabetic↑, *neuroP↑, CSCs↓, NOTCH↓, β-catenin/ZEB1↓, STAT3↓, TumCCA↑, *TNF-α↓, IL6↓, IL1β↓, *MMP9↓, *HO-1↑, cMyc↓, Mcl-1↓,
6818- EMD,    Emodin Rescued Hyperhomocysteinemia-Induced Dementia and Alzheimer's Disease-Like Features in Rats
- in-vivo, AD, NA
*Aβ↓, *p‑tau↓, *PP2A↑, *cAMP↑, *5LO↓, *IL6↓, *TNF-α↓, *ROS↓, *DNMT1↓,
6819- EMD,    Recent advances in the therapeutic potential of emodin for human health
- Review, Nor, NA
AntiCan↑, *AntiDiabetic↑, *neuroP↑, *Inflam↓, *antiOx↑, *BioAv↓, *BioAv↑, *SOD↑, *GPx↑, *GSH↑, *NRF2↑, *ROS↓, *lipid-P↓, *Cyt‑c↓, *BAX↓, *Bcl-2↓, *iNOS↓, *NO↓, *IL6↓, *IL10↓, *IL17↓, *IFN-γ↓, *NF-kB↓, *LC3II↓, *Akt↓, *Beclin-1↓, *AMPK↓, *TNF-α↓, *PGE2↓, *Apoptosis↓, *Casp3↓, *Casp9↓, *P53↓, *P21↓, *NAD↓, *ATP↓, *CHOP/DDIT3↓, *GADD34↓, *ATF4↓, tumCV↓, Apoptosis↑, TumCG↓, TumCI↓, TumMeta↓, CSCs↓, NOTCH1↓, STAT3↓, eff↑, miR-34a↓, *neuroP↑, *BDNF↓, *hepatoP↑, *ALAT↓, *AST↓, TG/TAG↓, ROS↑, Slug↓, EMT↓, Glycolysis↓, ChemoSen↑, P-gp↓, Ki-67↓, PCNA↓, ER Stress↑, TRIB3↑, NF-kB↑, TumMeta↑, *Imm↓, *toxicity↝,
7045- EMD,  TSG,    Synergic effects and possible mechanism of emodin and stilbene glycosides on colorectal cancer
- vitro+vivo, CRC, NA
Apoptosis↑, TumCMig↓, TumVol↓, IL6↓, TGF-β↓, i-P53↓, i-STAT3↓,
5487- EP,    High-frequency irreversible electroporation improves survival and immune cell infiltration in rodents with malignant gliomas
- in-vivo, GBM, NA
OS↑, CellMemb↑, Imm↑, Inflam↓, necrosis↑, Pyro↑, eff↑, IL2↑, IL6↑, IL17↑, IFN-γ↓,
6792- EPA,    Effect of Eicosapentaenoic Acid on Body Composition and Inflammation Markers in Patients with Head and Neck Squamous Cell Cancer from a Public Hospital in Mexico
- Trial, HNSCC, NA
Dose↝, *IL1β↓, *IL6↓, *TNF-α↓, *IFN-γ↓, QoL↑,
6381- Eug,    Biological Properties and Prospects for the Application of Eugenol—A Review
- Review, Var, NA
*eff↑, *BioAv↝, *BioAv↝, *BioAv↑, *antiOx↑, *AntiAg↑, *Inflam↓, *AntiBio↑, *MAOA↓, *neuroP↑, *ROS↓, *RNS↓, *eff↑, NF-kB↓, PGE2↓, COX2↓, TumCCA↑, Apoptosis↑, TumCMig↓, TumCI↓, tumCV↓, PI3K↓, Akt↓, MMPs↓, ChemoSen↑, ALDH↓, *Pain↓, *VGSC↓, *IL1β↓, *IL6↓, *TNF-α↓, *iNOS↓, *5LO↓, *chemoPv↑,
6388- Eug,    Eugenol’s anti-cancer properties, its modulation of signalling pathways, and cascades across various cancers: A review
- Review, Var, NA
Dose↝, AntiCan↑, *Inflam↓, *cardioP↑, *neuroP↑, angioG↓, TumMeta↓, *BioAv↑, *eff↑, *toxicity↝, antiNeop↑, TumCCA↑, Apoptosis↑, *antiOx↑, *lipid-P↓, *ROS↓, *SOD↑, *Catalase↑, *GSTs↑, *GPx↑, *iNOS↓, *COX2↓, *IL6↓, *TNF-α↓, *AntiArt↑, *Bacteria↓, TumAuto↑, PI3K↓, Akt↓, FOXO3↝, BAX↑, mTOR↓, NF-kB↓, P53↑, TumCG↓, CSCs↓, CD44↓, EpCAM↓, NOTCH1↓, OCT4↓, Bcl-2↓, PDK1↓, HER2/EBBR2↓, BAD↓, cycD1/CCND1↓, ROS↑, Casp3↑, selectivity↑, MMP2↓, MMP9↓, TIMP1↑, VEGF↓, VEGFR1↓, RECK↑, TIMP2↑, DNAdam↑, MMP↓, Thiols↓, PARP↑, *Pain↓, E2Fs↓, survivin↓,
6325- Eug,    Anticancer Properties of Eugenol: A Review
- Review, Var, NA
*antiOx↑, *AntiCan↑, *Inflam↓, TumCD↑, TumCCA↑, TumCMig↓, TumMeta↓, angioG↓, ChemoSen↑, chemoP↑, *BioAv↝, *BioAv↑, *BioAv↑, *BioAv↑, *Bacteria↓, *ROS↓, *IL6↓, *COX2↓, *TNF-α↓, *lipid-P↓, *SOD1↑, *Catalase↑, *GPx1↑, *GSTs↑, ROS↑, MMP↓, Apoptosis↑, COX2↓, TumCCA↑, E2Fs↓, PI3K↓, Akt↓, MMPs↓, CSCs↓, OCT4↓, CD44↓, EpCAM↓, NOTCH1↓, TumVol↓, Casp3↑, P53↑, cl‑PARP↑, MMP2↓, MMP9↓, TIMP1↑, ALDH↓, NF-kB↓, *toxicity↓,
6323- Eug,    Eugenol: An Insight Into the Anticancer Perspective and Pharmacological Aspects
- Review, Var, NA - Review, Arthritis, NA
*AntiCan↑, *AntiDiabetic↑, *cardioP↑, *toxicity↝, *GutMicro↑, *neuroP↑, *BioAv⇅, *BioAv↝, *antiOx↑, *Inflam↑, *AntiArt↑, *TNF-α↓, *IL6↓, *IL10↓, *GSH↑, *GPx↑, *Catalase↑, *MDA↓, *TAC↑, TumCMig↓, TumCI↓, Akt↑, FOXO3↑, Casp3↑, Casp9↑, P21↑, angioG↓, TumCI↓, Apoptosis↑, NF-kB↓, eff↑, eff↑, ChemoSen↑, NA↑, Casp3↑, Casp9↑, *AntiDiabetic↑, *glucose↓, *ROS↓, *Inflam↓, *MDA↓, *GSH↑, *BioAv↑,
6330- Eug,    Molecular Mechanisms of Action of Eugenol in Cancer: Recent Trends and Advancement
- Review, Var, NA
TumCD↑, TumCCA↑, AntiCan↑, Apoptosis↑, angioG↓, TumCI↓, TumMeta↓, ChemoSen↑, ALDH↓, NF-kB↓, IL6↓, IL8↓, BAX↑, cl‑Casp3↑, cl‑Casp9↑, cl‑PARP↑, Bcl-2↓, MMP2↓, MMP9↓, EMT↓, N-cadherin↓, Snail↓, E-cadherin↑, SOX2↓, ROS↑, PCNA↓, MMP1↓, Cyt‑c↑, LDH↑, CSCs↓, OCT4↓, NOTCH1↓, EpCAM↓, CD44↓, HER2/EBBR2↓, VEGF↓, TIMP2↑, eff↑, Ca+2↑, TumVol↓, DNAdam↑, GSH↓, H2O2↑, lipid-P↑,
5055- Ex,    Why exercise has a crucial role in cancer prevention, risk reduction and improved outcomes
- Review, Var, NA
OS↑, IGF-1↓, IGFBP3↑, BRCA1↑, BRCA2↑, RAS↓, P53↑, HSPs↑, Leptin↓, Irisin↓, Resistin↓, NK cell↑, CRP↓, IL6↓, TNF-α↓, PGE1↓, COX2↓, *GSH↑, *Catalase↑, *SOD↑, *monoA↑, *EndoR↑, *testos↑, ROS↑, QoL↑, BMD↑, BowelM↑,
3714- FA,    Recent Advances in the Neuroprotective Properties of Ferulic Acid in Alzheimer's Disease: A Narrative Review
- Review, AD, NA
*antiOx↑, *Inflam↓, *neuroP↑, *NF-kB↓, *NLRP3↓, *iNOS↓, *COX2↓, *TNF-α↓, *IL1β↓, *VCAM-1↓, *ICAM-1↓, *p‑MAPK↓, *p38↓, *JNK↓, *IL6↓, *IL8↓, *hepatoP↑, *RenoP↑, *Catalase↑, *PPARγ↑, *ROS↓, *Fenton↓, *IronCh↑, *SOD↑, *MDA↓, *lipid-P↓, *NRF2↑, *HO-1↑, *ARE↑, *Bil↑, *radioP↑, *GCLC↑, *GCLM↑, *NQO1↑, *Half-Life↝, *GutMicro↑, *Aβ↓, *BDNF↑, *Ca+2↓, *lipid-P↓, *PGE2↓, *cognitive↑, *ChAT↑, *memory↑, *Dose↝, *toxicity↓,
6871- FA,  Sesame,    Nano-encapsulated ferulic acid in sesame protein isolate alleviates acrylamide-induced liver toxicity and genotoxicity in rats via oxidative stress and DNA damage modulation
- in-vivo, Nor, NA
*GSH↑, *GPx↑, *SOD↓, *Catalase↑, *MDA↓, *IL6↓, *TNF-α↑, *DNAdam↓, *hepatoP↑, *BioAv↓, *BioAv↑,
6885- FA,    Mitigation of renal toxicity induced by paraquat using ferulic acid: Role of inflammatory pathways
- in-vivo, Nor, NA
*Dose↝, *TAC↑, *MDA↓, *RenoP↑, *PI3K↓, *Akt↓, *ROS↓, *Inflam↓, PPARγ↝, *NF-kB↓, *IL6↓, *TNF-α↓, *iNOS↓, *ALAT↓, *AST↓, *Urea↓, *Catalase↑, *SOD↑, *GPx↑, *GSH↑,
6962- FA,  VitB12,    Effects of Folic Acid and Vitamin B12, Alone and in Combination on Cognitive Function and Inflammatory Factors in the Elderly with Mild Cognitive Impairment: A Single-blind Experimental Design
- Trial, AD, NA
*Hcy/homoC↝, *IL6↓, *TNF-α↓, *MCP1/CCL2↝, *eff↑, *cognitive↑, *Inflam↓,
6951- FA,    Folic acid supplementation improves cognitive function by reducing the levels of peripheral inflammatory cytokines in elderly Chinese subjects with MCI
- Trial, AD, NA
*Dose↝, *cognitive↑, *Hcy/homoC↓, *IL6↓, *TNF-α↓,
6954- FA,    Folic acid as a potential therapeutic agent for Alzheimer's disease: Effects on inflammatory cytokines, amyloid deposition, and neurotransmitter metabolism
- Trial, AD, NA
*Inflam↓, *Aβ↓, *IL1β↓, *IL6↓, *TNF-α↓, *tau↓, *GABA↑, *5HT↑, *Ach↑, *Albumin↑, *HemoG↑, *neuroP↑, *Hcy/homoC↓,
6919- FIS,    Inhibition of c-Jun N-terminal kinase and nuclear factor κ B pathways mediates fisetin-exerted anti-inflammatory activity in lipopolysccharide-treated RAW264.7 cells
TumCP↓, Inflam↓, NO↓, iNOS↓, COX2↓, IL6↓, TNF-α↓, NF-kB↓, p‑cJun↓,
2861- FIS,    The neuroprotective effects of fisetin, a natural flavonoid in neurodegenerative diseases: Focus on the role of oxidative stress
- Review, Nor, NA - Review, Stroke, NA - Review, Park, NA
*antiOx↑, *ROS↓, *neuroP↑, *NO↑, BioAv↝, *BBB↑, *toxicity↑, *eff↑, *GSH↑, *SOD↑, *Aβ↓, *12LOX↓, *COX2↓, *Catalase↑, *Inflam↓, *TNF-α↓, *IL6↑, *lipid-P↓, NF-kB↓, IL1β↓, NRF2↑, HO-1↑, GSTs↑, cognitive↑, *BDNF↑,
2841- FIS,    Fisetin, an Anti-Inflammatory Agent, Overcomes Radioresistance by Activating the PERK-ATF4-CHOP Axis in Liver Cancer
- in-vitro, Nor, RAW264.7 - in-vitro, Liver, HepG2 - in-vitro, Liver, Hep3B - in-vitro, Liver, HUH7
*Inflam↓, *TNF-α↓, *IL1β↓, *IL6↓, Apoptosis↓, ER Stress↑, Ca+2↑, PERK↑, ATF4↑, CHOP/DDIT3↑, GRP78/BiP↑, tumCV↓, LDH↑, Casp3↑, cl‑Casp3↑, cl‑Casp8↑, cl‑Casp9↑, p‑eIF2α↑, RadioS↑,
2843- FIS,    Fisetin and Quercetin: Promising Flavonoids with Chemopreventive Potential
- Review, Var, NA
NRF2↑, Keap1↓, ChemoSen↑, BioAv↓, Cyt‑c↑, Casp3↑, Casp9↑, BAX↑, tumCV↓, Mcl-1↓, cl‑PARP↑, IGF-1↓, Akt↓, CDK6↓, TumCCA↑, P53?, cycD1/CCND1↓, cycE/CCNE↓, CDK2↓, CDK4↓, CDK6↓, MMP2↓, MMP9↓, MMP1↓, MMP7↓, MMP3↓, VEGF↓, PI3K↓, mTOR↓, COX2↓, Wnt↓, EGFR↓, NF-kB↓, ERK↓, ROS↑, angioG↓, TNF-α↓, PGE2↓, iNOS↓, NO↓, IL6↓, HSP70/HSPA5↝, HSP27↝,
6981- Form,    Formononetin: a review of its source, pharmacology, drug combination, toxicity, derivatives, and drug delivery systems
- Review, Var, NA - Review, AD, NA - Review, PSA, NA
BioAv↝, *memory↑, *ROS↓, *AChE↓, *NF-kB↓, *Keap1↝, *NRF2↑, *Inflam↓, *PGC-1α↝, *HO-1↓, *p‑tau↓, *cognitive↑, *BDNF↑, *5HT↑, *Stroke↓, *PARP1↓, *AIF↓, *Casp3↓, NP/CIPN↓, *neuroP↑, *NGF↑, *TNF-α↓, *IL1β↓, *IL18↓, *IL6↓, *VCAM-1↓, *pol-M2 MC↑, *hepatoP↑, *AST↓, *ALAT↓, *LC3II↑, *Beclin-1↑, *p62↑, *COX2↑, *MMP↑, *ATP↑, *GSH↑, *Catalase↑, *GPx↑, *MDA↓, *antiPs↑, *AntiDiabetic↑, *glucose↓, *Insulin↑, *GutMicro↑, *Obesity↓, COX2↓, cycD1/CCND1↓, TumCCA↑, EGFR↓, GSK‐3β↑, Mcl-1↓, *toxicity↓, TumCP↓, Hif1a↓, VEGF↓, ERK↓, LAMs↓, Cyt‑c↑, Casp9↑, Casp3↑, PARP↑, TumCD↑, mitA↑, BACH1↓, P53↓, ROS↑, PD-1↓, NF-kB↓, *Bacteria↓, *AntiViral↑, *mt-ROS?, *PI3K↓, *chemoP↑, ChemoSen↑, eff↑, *toxicity↓, *BioAv↑, *BioAv↑, *eff↑,
6995- Form,    Formononetin inhibits neuroinflammation and increases estrogen receptor beta (ERβ) protein expression in BV2 microglia
- Review, Nor, BV2
*TNF-α↓, *IL6↓, *IL1β↓, *PGE2↓, *iNOS↓, *COX2↓, *neuroP↑, *Inflam↓,
7035- GA,    Gallic acid attenuates LPS-induced inflammation in Caco-2 cells by suppressing the activation of the NF-κB/MAPK signaling pathway
- in-vitro, IBD, Caco-2
*Inflam↓, *antiOx↑, *CLDN1↓, *OCLN↓, *ZO-1↓, *IL6↓, *IL1β↓, *TNF-α↓, *BAX↓, *BAD↓, *Casp3↓, *Casp8↓, *ROS↓, *SOD↑, *Catalase↑, *GSH↑, *TJ↑, *Apoptosis↓, *NF-kB↓, *MAPK↓,
7028- GA,    Gallic acid: Pharmacological activities and molecular mechanisms involved in inflammation-related diseases
- Review, Nor, NA
*toxicity↓, *Inflam↓, *NF-kB↓, AntiTum↑, Bacteria↓, *AntiDiabetic↑, *Obesity↓, *AntiBio↑, *Stroke↓, *NO↓, *PGE2↓, *IL6↓, *MAPK↓, *TNF-α↓, *IL1β↓, *MCP1/CCL2↓, *ICAM-1↓, *TIMP1↓,
7080- GABA,    The Effect of Oral GABA on the Nervous System: Potential for Therapeutic Intervention
- Review, AD, NA
*BBB↝, *cognitive↑, *Dose↝, *toxicity↓, *Stress↓, *Inflam↓, *iNOS↓, *COX2↓, *IL6↓, *IL1β↓, *TNF-α↓, *Sleep↑, *Pain↓, *neuroP↑, *eff↑, *Ach↑, *AST↓, *ALAT↓, *BP↓, *other↝,
7052- Gallo,    Galloflavin Relieves the Malignant Behavior of Colorectal Cancer Cells in the Inflammatory Tumor Microenvironment
- in-vivo, Colon, SW48
TumCMig↓, TumCI↓, NLRP3↓, LDH↓, Inflam↓, IL6↓, TNF-α↓, IL1β↓,
7067- GamB,    Gambogic Acid and Its Role in Chronic Diseases
- Review, Var, NA
*NF-kB↓, PI3K↓, Akt↓, STAT3↓, STAT5↓, IL6↓, COX2↓, iNOS↓, MMPs↓, Src↓, PKA↓, CXCR4↑, VEGF↓, Bcl-2↓, Bcl-xL↓, IAP1↓, Mcl-1↓, survivin↓, cycD1/CCND1↓, HSP90↓, HSP70/HSPA5↓, MAPK↓, HATs↓, HDAC↓, FAK↓, ROS↑, MMP7↓, MMP9↓, α-tubulin↑, cl‑PARP↑, TNF-α↓, BID↑, BAD↑, Cyt‑c↑, Casp3↑, Casp9↑, *AntiArt↑, *antiPs↑,
805- GAR,  Cisplatin,  PacT,    Garcinol Exhibits Anti-Neoplastic Effects by Targeting Diverse Oncogenic Factors in Tumor Cells
- Review, NA, NA
ERK↓, PI3K/Akt↓, Wnt/(β-catenin)↓, STAT3↓, NF-kB↓, ChemoSen↑, COX2↓, Casp3↑, Casp9↑, BAX↑, Bcl-2↓, VEGF↓, TGF-β↓, HATs↓, E-cadherin↑, Vim↓, Zeb1↓, ZEB2↓, Let-7↑, MMP9↓, TumCCA↑, ROS↑, MMP↓, IL6↓, NOTCH1↓, antiNeop↑,
7212- GBE,    The Use of Ginkgo Biloba L. as a Neuroprotective Agent in the Alzheimer’s Disease
- Review, AD, NA
*antiOx↑, *ROS↓, *mitResp↑, *Casp9↓, *Casp3↓, *Apoptosis↓, *ATP↑, *neuroP↑, *IL1β↓, *IL6↓, *TNF-α↓, *PGE2↓, *memory↑, *cognitive↑, *BloodF↑, *lipid-P↓, *Aβ↓, *MAOA↓, *DA↑, *Dose↝, *toxicity↓,
7117- Ge-132,    Organogermanium suppresses cell death due to oxidative stress in normal human dermal fibroblasts
- in-vitro, Nor, NA
*IL6↓, *Apoptosis↓, *toxicity↓, Imm↑, IFN-γ↑, NK cell↑, AntiTum↑, Pain↓, *Wound Healing↑,
7130- Ge-132,    Phase I dose-escalation trial to repurpose propagermanium, an oral CCL2 inhibitor, in patients with breast cancer
- Trial, BC, NA
IL6↓, TumMeta↓, Dose↝, MCP1/CCL2↓,
6570- Ger,    Apoptosis-Mediated Anticancer Activity of Geraniol Inhibits NF-κB, MAPK, and JAK-STAT-3 Signaling Pathways in Human Thyroid Cancer Cells
- in-vitro, Thyroid, TPC-1
*Inflam↓, AntiCan↑, *neuroP↑, tumCV↓, TumCP↓, ROS↑, Apoptosis?, MMP↓, Bcl-2↓, cycD1/CCND1↓, cMyc↓, COX2↓, TNF-α↓, NF-kB↓, IL6↓, survivin↓, BAX↑, Casp3↑, JAK2↓, STAT3↓, ERK↓,
7140- GI,    Benefits of Ginger and Its Constituent 6-Shogaol in Inhibiting Inflammatory Processes
- Review, Var, NA
*Dose↝, *Inflam↓, *COX2↓, *iNOS↓, *NF-kB↓, *MAPK?, *HO-1↑, *PGE2↓, *TNF-α↓, *IL6↓, *IL1β↓, *IFN-γ↓, *MCP1/CCL2↓, *MIP2↓, *RANTES↓, *MPO↓, *NO↓, *Stroke↓, *BrainVol↑, *MDA↓, *ROS↓, *GSH↑, *NRF2↑, *antiOx↑, NLRP3↓, HDAC1↓,
7260- Gink,    Ginkgetin: A natural biflavone with versatile pharmacological activities
- Review, Var, NA - Review, Stroke, NA - Review, AD, NA
*AntiCan↑, *Inflam↓, *AntiBio↑, *neuroP↑, *TumCCA↑, Apoptosis↑, TumAuto↑, iNOS↓, COX2↓, PGE2↓, NF-kB↓, PLA2↓, *neuroP↑, *Stroke↓, *AntiFungal↓, *Bacteria↓, Bcl-xL↓, Bcl-2↓, Casp9↑, Casp3↑, cl‑PARP↑, IL6↓, STAT3↓, JAK1↓, survivin↓, COX2↓, IAP1↓, MMP2↓, MMP9↓, PTEN↑, SHP1↑, eff↑, TumVol↓, TumW↓, *toxicity↓, *ROS↓,
4003- Gins,    Neuroprotective Potentials of Panax Ginseng Against Alzheimer's Disease: A Review of Preclinical and Clinical Evidences
- Review, adrenal, NA
*neuroP↑, *Inflam↓, *ROS↓, *BACE↓, *PPARγ↑, *Aβ↓, *p‑tau↓, *NF-kB↓, *IL1β↓, *IL6↓, *TNF-α↓, *ROS↓, *CREB↓, *BDNF↑, *memory↑,
4511- GLA,    Gamma-Linolenic Acid (GLA) Protects against Ionizing Radiation-Induced Damage: An In Vitro and In Vivo Study
- vitro+vivo, Nor, RAW264.7
*radioP↑, *ROS↓, *DNAdam↓, *IL6↓, *TNF-α↓, *IL10↓, *NF-kB↓, *SOD↑, *Catalase↑, *GSH↑,
3768- H2,    Effects of Hydrogen Gas Inhalation on Community-Dwelling Adults of Various Ages: A Single-Arm, Open-Label, Prospective Clinical Trial
- Trial, AD, NA
*ROS↓, *NO↓, *BACE↓, *BDNF↑, *VEGF↑, *p‑tau↓, *MCP1/CCL2↓, *IL6↓, *cognitive↑, *toxicity∅,
3770- H2,    Role of Molecular Hydrogen in Ageing and Ageing-Related Diseases
- Review, AD, NA - Review, Park, NA
*antiOx↑, *NRF2↑, *HO-1↑, *Inflam↓, *neuroP↑, *cardioP↑, *other↓, *ROS↓, *NADPH↓, *Catalase↑, *GPx1↑, *NO↓, *mt-ROS↓, *SIRT3↑, *SIRT1↑, *TLR4↓, *mTOR↓, *cognitive↑, *Sepsis↓, *PTEN↓, *Akt↓, *NLRP3↓, *AntiAg↑, *IL6↓, *TNF-α↓, *IL1β↓, *MDA↓, *memory↑, *FOXO3↑, TumCG↓, *LDL↓,
3772- H2,    Therapeutic potential of hydrogen-rich water in zebrafish model of Alzheimer’s disease: targeting oxidative stress, inflammation, and the gut-brain axis
- in-vivo, AD, NA
*cognitive↑, *Aβ↓, *Inflam↓, *ROS↓, *GutMicro↑, *TNF-α↓, *IL6↓, *IL1β↓, *IL10↓, *Catalase↑, *GSH↑,
3773- H2,    Role and mechanism of molecular hydrogen in the treatment of Parkinson’s diseases
- Review, Park, NA
*neuroP↑, *antiOx↑, *Inflam↓, *ROS↓, *NADPH↓, *NRF2↑, *BBB↑, *IL1β↓, *IL6↓, *TNF-α↓, *NF-kB↓, *NLRP3↓, *Sepsis↓, *p‑mTOR↓, *AMPK↑, *SIRT1↑, *HO-1↑,
3787- H2,    Hydrogen, a Novel Therapeutic Molecule, Regulates Oxidative Stress, Inflammation, and Apoptosis
- Review, AD, NA
*Inflam↓, *antiOx↑, *ROS↓, *other↝, *NF-kB↓, *IL2↓, *IL6↓, *TNF-α↓, *HO-1↑, Apoptosis↑, TumAuto↑, *Sepsis↓, *NLRP3↓, Pyro↑,
3766- H2,    The role of hydrogen in Alzheimer′s disease
- Review, AD, NA
*antiOx↑, *Inflam↓, *AMPK↑, *SIRT1↑, *FOXO↑, *mtDam↓, *neuroP↑, *ROS↓, *p38↓, *cognitive↑, *BDNF↑, *memory↑, *lipid-P↓, *IL6↓, *TNF-α↓, *JNK↓, *NF-kB↓, *NLRP3↓,
4346- H2,    Medical Application of Hydrogen in Hematological Diseases
- Review, NA, NA
*AntiAg↑, *TNF-α↓, *IL6↓, *IFN-γ↓, *NF-kB↓,

Showing Research Papers: 151 to 200 of 355
Prev Page 4 of 8 Next

* indicates research on normal cells as opposed to diseased cells
Total Research Paper Matches: 355

Pathway results for Effect on Cancer / Diseased Cells:


NA, unassigned(tgid=0)

NA↑, 1,   PLA2↓, 1,  

Redox & Oxidative Stress(tgid=1)

Ceru↓, 1,   GSH↓, 1,   GSTs↑, 1,   H2O2↑, 1,   HO-1↑, 1,   Keap1↓, 1,   lipid-P↑, 1,   NRF2↓, 1,   NRF2↑, 2,   ROS↑, 12,   Thiols↓, 1,   Trx1↓, 1,  

Mitochondria & Bioenergetics(tgid=3)

MMP↓, 5,  

Core Metabolism/Glycolysis(tgid=4)

cMyc↓, 2,   GlutMet↓, 1,   Glycolysis↓, 1,   LDH↓, 1,   LDH↑, 2,   PDK1↓, 1,   PI3K/Akt↓, 1,   PPARγ↝, 1,   SIRT1↓, 1,  

Cell Death(tgid=5)

Akt↓, 5,   Akt↑, 1,   Apoptosis?, 1,   Apoptosis↓, 1,   Apoptosis↑, 10,   BAD↓, 1,   BAD↑, 1,   Bak↑, 1,   BAX↑, 6,   Bcl-2↓, 7,   Bcl-xL↓, 3,   BID↑, 1,   Casp3↑, 14,   cl‑Casp3↑, 2,   cl‑Casp8↑, 1,   Casp9↑, 8,   cl‑Casp9↑, 2,   Cyt‑c↑, 6,   HGF/c-Met↓, 1,   IAP1↓, 2,   iNOS↓, 4,   MAPK↓, 2,   Mcl-1↓, 4,   necrosis↑, 1,   Pyro↑, 2,   survivin↓, 4,   Telomerase↓, 1,   TumCD↑, 3,  

Kinase & Signal Transduction(tgid=6)

HER2/EBBR2↓, 2,   miR-25-5p↓, 1,  

Transcription & Epigenetics(tgid=7)

BowelM↑, 1,   p‑cJun↓, 1,   ac‑H3↑, 1,   ac‑H4↑, 1,   HATs↓, 3,   tumCV↓, 5,  

Protein Folding & ER Stress(tgid=8)

CHOP/DDIT3↑, 1,   p‑eIF2α↑, 1,   ER Stress↑, 3,   GRP78/BiP↑, 1,   HSP27↝, 1,   HSP70/HSPA5↓, 1,   HSP70/HSPA5↝, 1,   HSP90↓, 1,   HSPs↑, 1,   PERK↑, 1,  

Autophagy & Lysosomes(tgid=9)

TumAuto↑, 4,  

DNA Damage & Repair(tgid=10)

BRCA1↑, 1,   BRCA2↑, 1,   DNAdam↑, 2,   DNMT1↓, 1,   DNMTs↓, 1,   P53?, 1,   P53↓, 1,   P53↑, 4,   i-P53↓, 1,   PARP↑, 4,   cl‑PARP↑, 5,   PCNA↓, 2,  

Cell Cycle & Senescence(tgid=11)

CDK2↓, 1,   CDK4↓, 1,   cycD1/CCND1↓, 5,   cycE/CCNE↓, 1,   E2Fs↓, 2,   mitA↑, 1,   P21↑, 1,   TumCCA↑, 10,  

Proliferation, Differentiation & Cell State(tgid=12)

ALDH↓, 3,   CD44↓, 3,   CSCs↓, 5,   EMT↓, 3,   EpCAM↓, 3,   ERK↓, 4,   FOXO3↑, 1,   FOXO3↝, 1,   GSK‐3β↑, 1,   HDAC↓, 2,   HDAC1↓, 1,   IGF-1↓, 2,   IGFBP3↑, 1,   Let-7↑, 1,   miR-34a↓, 1,   mTOR↓, 2,   NOTCH↓, 1,   NOTCH1↓, 5,   OCT4↓, 3,   PI3K↓, 5,   PTEN↑, 2,   RAS↓, 1,   SHP1↑, 1,   SOX2↓, 1,   Src↓, 1,   STAT3↓, 7,   i-STAT3↓, 1,   STAT5↓, 1,   TumCG↓, 3,   Wnt↓, 1,   Wnt/(β-catenin)↓, 1,  

Migration(tgid=13)

BACH1↓, 1,   Ca+2↑, 2,   E-cadherin↑, 2,   FAK↓, 1,   Ki-67↓, 1,   LAMs↓, 1,   MMP1↓, 2,   MMP2↓, 5,   MMP3↓, 1,   MMP7↓, 2,   MMP9↓, 8,   MMPs↓, 5,   N-cadherin↓, 1,   PKA↓, 1,   RECK↑, 2,   Slug↓, 1,   Smad1↓, 1,   Snail↓, 1,   TGF-β↓, 3,   TIMP1↑, 3,   TIMP2↑, 2,   TRIB3↑, 1,   TumCI↓, 8,   TumCMig↓, 6,   TumCP↓, 5,   TumMeta↓, 6,   TumMeta↑, 1,   uPA↓, 1,   uPA↝, 1,   VEGFR1↓, 1,   Vim↓, 1,   Zeb1↓, 1,   ZEB2↓, 1,   α-tubulin↑, 1,   β-catenin/ZEB1↓, 1,  

Angiogenesis & Vasculature(tgid=14)

angioG↓, 7,   ATF4↑, 1,   EGFR↓, 3,   Hif1a↓, 2,   NO↓, 2,   VEGF↓, 7,  

Barriers & Transport(tgid=15)

CellMemb↑, 1,   P-gp↓, 1,  

Immune & Inflammatory Signaling(tgid=16)

COX2↓, 12,   CRP↓, 1,   CXCR4↑, 1,   IFN-γ↓, 1,   IFN-γ↑, 1,   IL17↑, 1,   IL1β↓, 3,   IL2↑, 1,   IL6↓, 14,   IL6↑, 1,   IL8↓, 2,   Imm↑, 3,   Inflam↓, 3,   IκB↑, 1,   JAK1↓, 1,   JAK2↓, 1,   MCP1/CCL2↓, 2,   NF-kB↓, 13,   NF-kB↑, 1,   NK cell↑, 2,   PD-1↓, 1,   PGE1↓, 1,   PGE2↓, 3,   RANTES?, 1,   Resistin↓, 1,   TNF-α↓, 6,  

Protein Aggregation(tgid=19)

NLRP3↓, 2,  

Hormonal & Nuclear Receptors(tgid=20)

CDK6↓, 2,   Irisin↓, 1,   Leptin↓, 1,  

Drug Metabolism & Resistance(tgid=21)

BioAv↓, 1,   BioAv↝, 2,   ChemoSen↑, 10,   Dose↝, 3,   eff↑, 9,   RadioS↑, 1,   selectivity↑, 2,  

Clinical Biomarkers(tgid=22)

BMD↑, 1,   BRCA1↑, 1,   CRP↓, 1,   EGFR↓, 3,   HER2/EBBR2↓, 2,   IL6↓, 14,   IL6↑, 1,   Ki-67↓, 1,   LDH↓, 1,   LDH↑, 2,   NOS2↓, 1,   TG/TAG↓, 1,   TRIB3↑, 1,  

Functional Outcomes(tgid=23)

AntiCan↑, 5,   antiNeop↑, 2,   AntiTum↑, 2,   chemoP↑, 2,   cognitive↑, 1,   NP/CIPN↓, 1,   OS↑, 2,   Pain↓, 1,   QoL↑, 2,   TumVol↓, 4,   TumW↓, 1,  

Infection & Microbiome(tgid=24)

Bacteria↓, 1,  
Total Targets: 227

Pathway results for Effect on Normal Cells:


NA, unassigned(tgid=0)

AntiArt↑, 3,   AntiBio↑, 5,   DA↑, 1,   Stress↓, 1,   Stroke↓, 4,  

Redox & Oxidative Stress(tgid=1)

antiOx↑, 16,   ARE↑, 1,   Bil↑, 1,   Catalase↑, 14,   Fenton↓, 1,   GCLC↑, 1,   GCLM↑, 1,   GPx↑, 7,   GPx1↑, 2,   GSH↑, 12,   GSTs↑, 2,   HO-1↓, 1,   HO-1↑, 6,   Keap1↝, 1,   lipid-P↓, 8,   MDA↓, 8,   MPO↓, 1,   NQO1↑, 1,   NRF2↑, 8,   RNS↓, 2,   ROS↓, 25,   mt-ROS?, 1,   mt-ROS↓, 1,   SIRT3↑, 1,   SOD↓, 1,   SOD↑, 9,   SOD1↑, 2,   SOD2↑, 1,   TAC↑, 2,  

Metal & Cofactor Biology(tgid=2)

IronCh↑, 1,  

Mitochondria & Bioenergetics(tgid=3)

AIF↓, 1,   ATP↓, 1,   ATP↑, 2,   Insulin↑, 1,   mitResp↑, 1,   MMP↑, 1,   mtDam↓, 1,   PGC-1α↝, 1,  

Core Metabolism/Glycolysis(tgid=4)

12LOX↓, 1,   ALAT↓, 4,   AMPK↓, 1,   AMPK↑, 2,   cAMP↑, 1,   CREB↓, 1,   glucose↓, 2,   LDL↓, 2,   NAD↓, 1,   NADPH↓, 2,   PPARγ↑, 2,   SIRT1↑, 3,  

Cell Death(tgid=5)

Akt↓, 3,   Apoptosis↓, 4,   BAD↓, 1,   BAX↓, 2,   Bcl-2↓, 1,   Casp3↓, 4,   Casp8↓, 1,   Casp9↓, 2,   Cyt‑c↓, 1,   GADD34↓, 1,   iNOS↓, 9,   JNK↓, 2,   MAPK?, 1,   MAPK↓, 2,   p‑MAPK↓, 1,   p38↓, 2,  

Transcription & Epigenetics(tgid=7)

Ach↑, 2,   other↓, 2,   other↝, 2,  

Protein Folding & ER Stress(tgid=8)

CHOP/DDIT3↓, 1,  

Autophagy & Lysosomes(tgid=9)

Beclin-1↓, 1,   Beclin-1↑, 1,   LC3II↓, 1,   LC3II↑, 1,   p62↑, 1,  

DNA Damage & Repair(tgid=10)

DNAdam↓, 2,   DNMT1↓, 1,   P53↓, 2,   PARP1↓, 1,  

Cell Cycle & Senescence(tgid=11)

E2Fs↑, 1,   P21↓, 1,   TumCCA↑, 1,  

Proliferation, Differentiation & Cell State(tgid=12)

FOXO↑, 1,   FOXO3↑, 1,   IGF-1R↓, 1,   mTOR↓, 2,   p‑mTOR↓, 1,   PI3K↓, 2,   PTEN↓, 1,   VGSC↓, 1,  

Migration(tgid=13)

5LO↓, 2,   AntiAg↑, 3,   AP-1↓, 1,   Ca+2↓, 2,   CLDN1↓, 1,   MMP2↓, 1,   MMP9↓, 1,   TIMP1↓, 1,   TJ↑, 1,   VCAM-1↓, 2,   ZO-1↓, 1,  

Angiogenesis & Vasculature(tgid=14)

ATF4↓, 1,   NO↓, 6,   NO↑, 1,   PDGFR-BB↓, 1,   VEGF↑, 1,  

Barriers & Transport(tgid=15)

BBB↑, 3,   BBB↝, 1,   OCLN↓, 1,  

Immune & Inflammatory Signaling(tgid=16)

COX2↓, 8,   COX2↑, 1,   ICAM-1↓, 2,   IFN-γ↓, 4,   IL10↓, 4,   IL17↓, 1,   IL18↓, 1,   IL1β↓, 16,   IL2↓, 1,   IL6↓, 34,   IL6↑, 1,   IL8↓, 3,   Imm↓, 1,   Inflam↓, 27,   Inflam↑, 2,   JAK↓, 1,   pol-M2 MC↑, 1,   MCP1/CCL2↓, 3,   MCP1/CCL2↝, 1,   MIP2↓, 1,   NF-kB↓, 15,   PGE2↓, 6,   RANTES↓, 1,   TLR4↓, 1,   TNF-α↓, 33,   TNF-α↑, 1,  

Synaptic & Neurotransmission(tgid=18)

5HT↑, 2,   AChE↓, 1,   BDNF↓, 1,   BDNF↑, 6,   BrainVol↑, 1,   ChAT↑, 1,   EndoR↑, 1,   GABA↑, 1,   MAOA↓, 2,   monoA↑, 1,   NGF↑, 1,   tau↓, 1,   p‑tau↓, 5,  

Protein Aggregation(tgid=19)

Aβ↓, 8,   BACE↓, 2,   NLRP3↓, 6,   PP2A↑, 1,  

Hormonal & Nuclear Receptors(tgid=20)

testos↑, 1,  

Drug Metabolism & Resistance(tgid=21)

BioAv↓, 6,   BioAv↑, 13,   BioAv⇅, 1,   BioAv↝, 5,   Dose↝, 7,   eff↑, 8,   Half-Life↝, 2,  

Clinical Biomarkers(tgid=22)

ALAT↓, 4,   Albumin↑, 1,   AST↓, 4,   Bil↑, 1,   BloodF↑, 1,   BP↓, 1,   GutMicro↑, 6,   Hcy/homoC↓, 2,   Hcy/homoC↝, 1,   HemoG↑, 1,   IL6↓, 34,   IL6↑, 1,   Urea↓, 1,  

Functional Outcomes(tgid=23)

AntiCan↑, 5,   AntiDiabetic↑, 6,   antiPs↑, 2,   cardioP↑, 5,   chemoP↑, 1,   chemoPv↑, 1,   cognitive↑, 10,   hepatoP↓, 1,   hepatoP↑, 5,   memory↑, 6,   neuroP↑, 22,   Obesity↓, 3,   Pain↓, 3,   radioP↑, 2,   RenoP↑, 2,   Sleep↑, 1,   toxicity↓, 9,   toxicity↑, 1,   toxicity↝, 4,   toxicity∅, 1,   Wound Healing↑, 1,  

Infection & Microbiome(tgid=24)

AntiFungal↓, 1,   AntiViral↑, 3,   Bacteria↓, 5,   Sepsis↓, 3,  
Total Targets: 203

Scientific Paper Hit Count for: IL6, Interleukin-6
15 Curcumin
15 Quercetin
13 Hydrogen Gas
12 Lycopene
12 Sulforaphane (mainly Broccoli)
9 EGCG (Epigallocatechin Gallate)
9 Magnetic Fields
8 Propolis -bee glue
8 Resveratrol
8 Silymarin (Milk Thistle) silibinin
8 Shikonin
8 Thymoquinone
7 Baicalein
7 Beta-Caryophyllene
7 Celastrol
7 Urolithin
6 Artemisinin
6 Berberine
6 Boron
6 Rosmarinic acid
5 Alpha-Lipoic-Acid
5 Ashwagandha(Withaferin A)
5 Crocetin
5 Eugenol
5 Luteolin
4 Silver-NanoParticles
4 Cisplatin
4 Boswellia (frankincense)
4 α-Bisabolol / Chamomile oil
4 Chlorogenic acid
4 Piperine
4 Ellagic acid
4 Emodin
4 Folic Acid, Vit B9
4 Fisetin
4 Piperlongumine
4 Vitamin C (Ascorbic Acid)
3 Allicin (mainly Garlic)
3 Apigenin (mainly Parsley)
3 Melatonin
3 Butyrate
3 Caffeic acid
3 Chemotherapy
3 Ferulic acid
3 Honokiol
3 Magnetic Field Rotating
3 Pterostilbene
3 Selenite (Sodium)
2 Auranofin
2 Astragalus
2 Anethole/trans-Anethole
2 Ascorbyl Palmitate
2 Astaxanthin
2 Aloe anthraquinones
2 beta-glucans
2 Baicalin
2 Betulinic acid
2 borneol
2 Selenium
2 Capsaicin
2 Carvacrol
2 Chrysin
2 Coenzyme Q10
2 Ursolic acid
2 eicosapentaenoic acid
2 diet Fermented Foods
2 Dandelion Root
2 Vitamin B12
2 Formononetin
2 Gallic acid
2 Paclitaxel/Taxol
2 Germanium Organic/Ge-132 / propagermanium (organogermanium)
2 Nimbolide
2 Rutin
2 Selenium NanoParticles
1 1,8-Cineole
1 2-DeoxyGlucose
1 alpha Linolenic acid
1 Andrographis
1 Fennel Oil/Foeniculum vulgare
1 Atorvastatin
1 immunotherapy
1 Berbamine
1 Biochanin A
1 xanthohumol
1 Bacopa monnieri
1 Bruteridin(bergamot juice)
1 Carnosine
1 Centella asiatica / Gotu kola → asiaticoside
1 Cinnamon
1 Oxygen, Hyperbaric
1 Docosahexaenoic Acid
1 diet Short Term Fasting
1 D-limonene
1 Radiotherapy/Radiation
1 Ginkgo biloba-EGb 761
1 Tetrahydroxystilbene glucoside
1 Electrical Pulses
1 Exercise
1 Sesame seeds and Oil
1 Gamma-aminobutyric acid
1 Galloflavin
1 Gambogic Acid
1 Garcinol
1 Ginkgo biloba
1 Geraniol
1 Ginger/6-Shogaol/Gingerol
1 Ginkgetin
1 Ginseng
1 γ-linolenic acid (Borage Oil)
1 HydroxyCitric Acid
1 Orlistat
1 Juglone
1 Potassium
1 Linalool
1 5-fluorouracil
1 Methylsulfonylmethane
1 Naringin
1 Niclosamide (Niclocide)
1 Oleuropein
1 probiotics
1 Bifidobacterium
1 Phosphatidylserine
1 Perilla
1 Docetaxel
1 Salvia miltiorrhiza
1 Aflavin-3,3′-digallate
1 Turmerones
1 Vitamin B3,Niacin
Query results interpretion may depend on "conditions" listed in the research papers.
Such Conditions may include : 
  -low or high Dose
  -format for product, such as nano of lipid formations
  -different cell line effects
  -synergies with other products 
  -if effect was for normal or cancerous cells
Filter Conditions: Pro/AntiFlg:%  IllCat:%  CanType:%  Cells:%  prod#:%  Target#:158  State#:%  Dir#:%
wNotes=0 sortOrder:rid,rpid

 

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