OS Cancer Research Results

OS, overall survival: Click to Expand ⟱
Source:
Type:
Overall survival

Scientific Papers found: Click to Expand⟱
7489- H2,    Molecular Hydrogen in the Treatment of Respiratory Diseases
- Review, Asthma, NA
*antiOx↑, *Inflam↓, *Apoptosis↓, *Dose↓, *Dose↝, *eff↑, *ROS↓, *RNS↓, *NRF2↑, *HO-1↑, *Fenton↓, *NLRP3↓, *NADPH↓, *NOX4↓, *NOX↓, *MPO↓, *NF-kB↓, *TNF-α↓, *IL6↓, *IL1β↓, *HMGB1↓, *IL4↑, *IL10↑, *M2 MC↑, *Treg lymp↝, *Bcl-2↑, *Bcl-xL↑, *PI3K↑, *Akt↑, *JAK2↑, *STAT3↑, *Dose↑, *CD4+↑, *CD25+↑, *FOXP3↑, *MDA↓, *SOD↑, *Catalase↑, *Casp3↓, *Casp9↓, *TBARS↓, *SpO2↑, *VitE↓, *OS↑, *Weight↑, *DNAdam↓, *PGE2↓, *MCP1/CCL2↓, *lipid-P↓, *TumCP↓, *tumCV↓, *TumCMig↓, *TumCI↓, TumW↓, TumVol↓, selectivity↑, QoL↑, ChemoSen↑, chemoP↑, radioP↑, ROS↑, NLRP3↑, Casp3↑, VEGF↓, Wnt↓, β-catenin/ZEB1↓,
4235- H2,    PPARα contributes to the therapeutic effect of hydrogen gas against sepsis-associated encephalopathy with the regulation to the CREB-BDNF signaling pathway and hippocampal neuron plasticity-related gene expression
- in-vivo, Sepsis, NA
*PPARα↑, *CREB↑, *BDNF↑, *OS↑, *cognitive↑,
4306- H2,    Molecular Hydrogen as an Emerging Candidate for Preventing Alzheimer’s Disease
- Review, AD, NA
*ROS↓, *memory↑, *neuroP↑, *OS↑, *Inflam↓,
2511- H2,    Molecular hydrogen suppresses glioblastoma growth via inducing the glioma stem-like cell differentiation
- in-vivo, GBM, U87MG
TumCG↓, OS↑, CD133↓, Ki-67↓, angioG↓, Diff↑, TumCMig↓, TumCI↓, Dose↝, BBB↑, mt-ROS↑,
2525- H2,    Hydrogen-Rich Saline Attenuates Cardiac and Hepatic Injury in Doxorubicin Rat Model by Inhibiting Inflammation and Apoptosis
- in-vivo, NA, NA
OS↓, cardioP↑, *AST↓, ALAT↓, *ROS↓, *MDA↓, *hepatoP↑, *Inflam↓, chemoP↑,
2523- H2,    Prospects of molecular hydrogen in cancer prevention and treatment
- Review, Var, NA
ROS↓, TumCP↓, TumMeta↓, AntiTum↑, GutMicro↑, Inflam↓, OS↑, radioP↑, selectivity↑, SOD↑, IL1β↑, IL8↑, TNF-α↑, neuroP↑,
2522- H2,    A Systematic Review of Molecular Hydrogen Therapy in Cancer Management
- Review, Var, NA
chemoP↑, OS↑, QoL↑, TumVol↑, ROS↑, AntiTum↑, other↝,
2519- H2,    Hydrogen: an advanced and safest gas option for cancer treatment
- Review, Var, NA
antiOx↑, neuroP↓, BBB↑, toxicity∅, TumCP↓, Apoptosis↓, ROS↑, Hif1a↓, NF-kB↓, P53?, OS↑, chemoP↑,
2505- H2,    Hydrogen gas restores exhausted CD8+ T cells in patients with advanced colorectal cancer to improve prognosis
- Trial, CRC, NA
PGC-1α↑, Dose↝, CD8+↑, OS↑,
2504- H2,    Hydrogen gas activates coenzyme Q10 to restore exhausted CD8+ T cells, especially PD-1+Tim3+terminal CD8+ T cells, leading to better nivolumab outcomes in patients with lung cancer
- Trial, Lung, NA
CD8+↑, OS↑, eff↝, CoQ10↑, PDT+↓, PGC-1α↑, Dose↝, *toxicity∅,
2503- H2,    Brain Metastases Completely Disappear in Non-Small Cell Lung Cancer Using Hydrogen Gas Inhalation: A Case Report
- Case Report, Lung, NA
TumVol↓, OS↑, Dose↝, Dose↝, CEA↓, CA125↓, CYFRA21-1↓, SIRT1↓, COX2/PTGS2↓, IL1β↓, IL6↓, TNF-α↓, HMGB1↓, NF-kB↓, EP2↓,
3152- H2,  VitC,  Rad,    Hydrogen and Vitamin C Combination Therapy: A Novel Method of Radioprotection
- in-vitro, Nor, HUVECs - in-vivo, NA, NA
AntiTum↑, OS↑, QoL↑, TumVol↓, radioP↑, Dose↑, Dose↝, eff↑,
3771- H2,    Molecular Hydrogen Neuroprotection in Post-Ischemic Neurodegeneration in the Form of Alzheimer’s Disease Proteinopathy: Underlying Mechanisms and Potential for Clinical Implementation—Fantasy or Reality?
- Review, AD, NA - Review, Stroke, NA
*cognitive↑, AntiCan↑, *Inflam↓, *antiOx↑, *ROS↓, *neuroP↑, *SOD↑, *GPx↑, *MDA↑, *BBB↑, *OS↑, *Ca+2↓, *APP↓, *p‑tau↓,
3762- H2,    Effects of Molecular Hydrogen Assessed by an Animal Model and a Randomized Clinical Study on Mild Cognitive Impairment
- in-vivo, AD, NA
*ROS↓, *memory↑, *neuroP↑, *cognitive↑, *OS↑,
286- HCA,  ALA,    Adding a combination of hydroxycitrate and lipoic acid (METABLOC™) to chemotherapy improves effectiveness against tumor development: experimental results and case report
OS↑,
1415- HCA,    Hydroxycitrate delays early mortality in mice and promotes muscle regeneration while inducing a rich hepatic energetic status
- in-vivo, Nor, NA
*OS↑, *toxicity↓, *AST∅, *ALAT∅, *Strength↑, *memory∅, *other↑, *other↑, *other↑,
1637- HCA,  OLST,    Orlistat and Hydroxycitrate Ameliorate Colon Cancer in Rats: The Impact of Inflammatory Mediators
- in-vivo, Colon, NA
TumVol↓, OS↑, *IL6↓, *NF-kB↓, *eff↑, *Casp3↓, *TNF-α↓, *Catalase↑, *NO↓, *ROS↓, *Inflam↓, *Apoptosis↓,
1438- HCQ,  Chemo,    Adding Chloroquine to Conventional Treatment for Glioblastoma Multiforme
- Trial, GBM, NA
OS↑, *toxicity∅,
7505- HCQ,  GEM,  PacT,    A Randomized Phase II Preoperative Study of Autophagy Inhibition with High-Dose Hydroxychloroquine and Gemcitabine/Nab-Paclitaxel in Pancreatic Cancer Patients
- Trial, PC, NA
eff↑, TumAuto↓, Imm↑, CA19-9↓, OS↑,
7461- HNK,    Honokiol: a potent chemotherapy candidate for human colorectal carcinoma
- vitro+vivo, CRC, RKO
Apoptosis↑, Casp↑, Dose↝, OS↑, *Inflam↓, *AntiThr↑, *antiOx↑, *Half-Life↝, TumCG↓,
2872- HNK,    Honokiol alleviated neurodegeneration by reducing oxidative stress and improving mitochondrial function in mutant SOD1 cellular and mouse models of amyotrophic lateral sclerosis
- in-vivo, ALS, NA - NA, Stroke, NA - NA, AD, NA - NA, Park, NA
*eff↑, *ROS↓, *GSH↑, *NRF2↑, *motorD↑, *OS↑, *neuroP↑, *BBB↑, *cognitive↑, *eff↑, *antiOx↑, *Cyt‑c↑, *PGC-1α↑,
2864- HNK,    Honokiol: A Review of Its Anticancer Potential and Mechanisms
- Review, Var, NA
TumCCA↑, CDK2↓, EMT↓, MMPs↓, AMPK↑, TumCI↓, TumCMig↓, TumMeta↓, VEGFR2/KDR/Flk1↓, *antiOx↑, *Inflam↓, *BBB↑, *neuroP↑, *ROS↓, Dose↝, selectivity↑, Casp3↑, Casp9↑, NOTCH1↓, cycD1/CCND1↓, cMyc↓, P21?, DR5↑, cl‑PARP↑, P53↑, Mcl-1↑, p65↓, NF-kB↓, ROS↑, JNK↑, NRF2↑, cJun↑, EF-1α↓, MAPK↓, PI3K↓, mTORC1↓, CSCs↓, OCT4↓, Nanog↓, SOX4↓, STAT3↓, CDK4↓, p‑RB1↓, PGE2↓, COX2/PTGS2↓, β-catenin/ZEB1↑, IKKα↓, HDAC↓, HATs↑, H3↑, H4↑, LC3II↑, c-Raf↓, SIRT3↑, Hif1a↓, ER Stress↑, GRP78/BiP↑, cl‑CHOP/DDIT3↑, MMP↓, PCNA↓, Zeb1↓, NOTCH3↓, CD133↓, Nestin↓, ATG5↑, ATG7↑, survivin↓, ChemoSen↑, SOX2↓, OS↑, P-gp/ABCB1↓, Half-Life↓, Half-Life↝, eff↑, BioAv↓,
7650- HPT,    Hyperthermia and radiation therapy for locally advanced or recurrent breast cancer
- Trial, BC, NA
OS↑, LC↑,
7599- HPT,  Rad,    Recent development on hyperthermia: An effective cotreatment improving radiotherapy outcome
- Review, Var, NA
NA↑, RadioS↑, DNArepair↓, Hypoxia↓, EPR↑, LC↑, OS↑, *toxicity↓, Dose↝, BloodF↑, pH↝, Imm↑, HSP70/HSPA5↑,
7598- HPT,  Rad,  Chemo,    The role of capacitive hyperthermia as an adjunct treatment in oncology: a systematic review of randomized phase III trials
- Review, Var, NA
OS↑, TR↑, LC↑, *toxicity?,
7622- HPT,    A Review of the Current Clinical Evidence for Loco-Regional Moderate Hyperthermia in the Adjunct Management of Cancers
- Review, Var, NA
LC↑, OS↑, QoL↑, toxicity↓, Dose↝, Dose↝, ROS↑, DNArepair↓, EPR↑, DNAdam↑, HSP70/HSPA5↑, BloodF↑, Hypoxia↓,
7597- HPT,    Comparison of radiotherapy alone with radiotherapy plus hyperthermia in locally advanced pelvic tumours: a prospective, randomised, multicentre trial. Dutch Deep Hyperthermia Group
- Trial, Var, NA
ORR↑, OS↑,
7624- HPT,  Chemo,    A multicentre randomised clinical trial of chemoradiotherapy plus hyperthermia versus chemoradiotherapy alone in patients with locally advanced cervical cancer
- Trial, Cerv, NA
OS↑, CR↑, *toxicity↓,
7627- HPT,  Rad,    Local control rate after the combination of re-irradiation and hyperthermia for irresectable recurrent breast cancer: Results in 248 patients
CR↑, OS↑, *toxicity↝, RadioS↑,
7578- IMA,    Long-Term Outcomes of Imatinib Treatment for Chronic Myeloid Leukemia
- Trial, CML, NA
OS↑, toxicity↓, BCR-ABL↓,
7579- IMA,    One vs three years of adjuvant imatinib for operable gastrointestinal stromal tumor: a randomized trial
- Trial, GC, NA
RFS↑, OS↑,
7631- Ins,  IP6,    Broad Spectrum Anticancer Activity of Myo-Inositol and Inositol Hexakisphosphate
- Review, Var, NA
other↑, p‑pRB↓, TumCCA↑, PI3K↓, Akt↓, ERK↓, NF-kB↓, COX2/PTGS2↓, PGE2↓, PSEN1/PS1↓, EMT↓, Wnt↓, β-catenin/ZEB1↓, NOTCH1↓, N-cadherin↓, Snail↓, E-cadherin↑, fascin↓, Cofilin↓, MMPs↓, ROCK1↓, Dose↝, other↝, selectivity↑, *ROS↓, *lipid-P↓, ROS↑, NK cell↑, Imm↑, TNF-α↓, ChemoSen↑, Dose↑, toxicity↓, QoL↑, chemoP↑, OS↑, Dose↝, Insulin↓, glucose↝, lipoGen↓, eff↑,
7672- iod,    Adjuvant Effect of Molecular Iodine in Conventional Chemotherapy for Breast Cancer. Randomized Pilot Study
- Trial, BC, NA
Dose↝, OS↑, TumCI↓, Apoptosis↑, EstroRS/ERS↑, eff↑, *cardioP↑, *antiOx↑, *Inflam↓,
7683- iod,  Se,    Prediagnostic serum iodine and selenium in relation to breast cancer survival
- Study, BC, NA
OS↑, other⇅,
7684- iod,    Molecular iodine impairs chemotherapy resistance and adverse effects in breast cancer treatments
- Trial, BC, NA
Dose↝, OS↑, antiNeop↑, eff↑,
7697- IP6,  Ins,    Combination of Inositol Hexaphosphate and Inositol Inhibits Liver Metastasis of Colorectal Cancer in Mice Through the Wnt/β-Catenin Pathway
- in-vivo, CRC, NA
TumMeta↓, OS↑, TumW↓, Wnt↓, TCF7/TCF1↓, cMyc↓,
7702- IP6,  Ins,  capec,    Inositol Hexakisphosphate and Inositol Enhance the Inhibition of Colorectal Cancer Growth and Liver Metastasis by Capecitabine in a Mouse Model
- in-vivo, CRC, NA
Dose↝, AntiTum↑, OS↑, TumW↓, TumMeta↓, E-cadherin↑, N-cadherin↓, Vim↓, TNF-α↓, IL6↓, IL8↓, ChemoSen↑,
7783- ISL,    Isoliquiritigenin Inhibits Ovarian Cancer Metastasis by Reversing Epithelial-to-Mesenchymal Transition
- vitro+vivo, Ovarian, SKOV3 - in-vitro, Ovarian, OVCAR-3
EMT↓, E-cadherin↑, TumCMig↓, TumCI↓, OS↑, Zeb1↓, Vim↓, N-cadherin↓,
7736- isoFl,    Dietary isoflavone intake and all-cause mortality in breast cancer survivors: The Breast Cancer Family Registry
- Review, BC, NA
OS↑,
7734- isoFl,    Dietary Isoflavone Intake and Breast Cancer Prognosis: A Prospective Analysis and Meta-Analysis
- Review, BC, NA
OS↑,
8009- itraC,    Itraconazole exerts its anti-melanoma effect by suppressing Hedgehog, Wnt, and PI3K/mTOR signaling pathways
- vitro+vivo, Melanoma, SK-MEL-28 - vitro+vivo, Melanoma, A375
OS↑, TumCP↓, Ki-67↓, TumCP↓, Gli1↓, GLI2↓, Wnt↓, β-catenin/ZEB1↓, cycD1/CCND1↓, AXIN1↑, GLI3↑, AXIN1↑, HH↓, PI3K↓, Akt↓, *toxicity↓,
8001- itraC,    Repurposing itraconazole as an anticancer agent
- Review, Var, NA
*AntiFungal↑, AntiCan↑, P-gp/ABCB1↓, HH↓, mTOR↓, Wnt↓, β-catenin/ZEB1↓, angioG↓, LymphAG↓, ChemoSen↑, OS↑, Gli1↓, Ki-67↓, CSCs↓,
8013- itraC,    High-dose itraconazole as a non-castrating therapy for a patient with biochemically-recurrent prostate cancer
- Case Report, Pca, NA
*AntiFungal↑, antiNeop↑, HH↓, Dose↝, OS↑, testos∅, Dose↝, PSA↓, other↝, other↝, HH↓,
8016- itraC,    Impact of combination chemotherapy with itraconazole on survival for patients with recurrent or persistent ovarian clear cell carcinoma
- Human, Ovarian, NA
P-gp/ABCB1↓, angioG↓, HH↓, OS↑, Dose↝,
8018- itraC,  Chemo,    Impact of combination chemotherapy with itraconazole on survival of patients with refractory ovarian cancer
- Trial, Ovarian, NA
PFS↑, OS↑, other↝,
2179- itraC,    Repurposing itraconazole for the treatment of cancer
- Review, Var, NA
HH↓, angioG↓, TumCCA↑, MDR1↓, P-gp/ABCB1↓, mTOR↓, VEGF↓, Smo↓, Gli1↓, OS↑, PSA↓,
2177- itraC,    Itraconazole improves survival outcomes in patients with colon cancer by inducing autophagic cell death and inhibiting transketolase expression
- Study, Colon, NA - in-vitro, CRC, COLO205 - in-vitro, CRC, HCT116
OS↑, tumCV↓, Casp3↑, TumCCA↑, HH↓, TumAuto↑, LC3B↑, p62↑, TKT↓,
7897- IVT,  VT,    Vitexin and isovitexin delayed ageing and enhanced stress-resistance through the activation of the SKN-1/Nrf2 signaling pathway
- in-vitro, Nor, NA
*antiOx↑, *ROS↓, *OS↑, *NRF2↑, *AntiAg↑,
8005- JG,    Immunomodulation by juglone alleviates acute graft-versus-host disease without compromising the graft-versus-leukaemia activity in mice
- in-vivo, AML, NA
DCells↓, CD4+↓, OS↑, Imm↝,
5119- JG,    Juglone Suppresses Inflammation and Oxidative Stress in Colitis Mice
- in-vivo, Nor, NA
*antiOx↑, *OS↑, *IL6↓, *IL12↓, *IL23↓, *TNF-α↓, *Inflam↓, *NF-kB↓, *NFE2L2↓, *ROS↓,

Showing Research Papers: 151 to 200 of 326
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* indicates research on normal cells as opposed to diseased cells
Total Research Paper Matches: 326

Pathway results for Effect on Cancer / Diseased Cells:


NA, unassigned(tgid=0)

CR↑, 2,   LC↑, 4,   NA↑, 1,   ORR↑, 1,   PFS↑, 1,   PSEN1/PS1↓, 1,   RFS↑, 1,   TCF7/TCF1↓, 1,   TR↑, 1,  

Redox & Oxidative Stress(tgid=1)

antiOx↑, 1,   CoQ10↑, 1,   NRF2↑, 1,   ROS↓, 1,   ROS↑, 6,   mt-ROS↑, 1,   SIRT3↑, 1,   SOD↑, 1,   TKT↓, 1,  

Mitochondria & Bioenergetics(tgid=3)

BCR-ABL↓, 1,   Insulin↓, 1,   MMP↓, 1,   PGC-1α↑, 2,   c-Raf↓, 1,  

Core Metabolism/Glycolysis(tgid=4)

ALAT↓, 1,   AMPK↑, 1,   ATG7↑, 1,   cMyc↓, 2,   glucose↝, 1,   lipoGen↓, 1,   SIRT1↓, 1,  

Cell Death(tgid=5)

Akt↓, 2,   Apoptosis↓, 1,   Apoptosis↑, 2,   Casp↑, 1,   Casp3↑, 3,   Casp9↑, 1,   DR5↑, 1,   JNK↑, 1,   MAPK↓, 1,   Mcl-1↑, 1,   survivin↓, 1,  

Kinase & Signal Transduction(tgid=6)

EF-1α↓, 1,  

Transcription & Epigenetics(tgid=7)

cJun↑, 1,   H3↑, 1,   H4↑, 1,   HATs↑, 1,   other↑, 1,   other⇅, 1,   other↝, 5,   p‑pRB↓, 1,   tumCV↓, 1,  

Protein Folding & ER Stress(tgid=8)

cl‑CHOP/DDIT3↑, 1,   ER Stress↑, 1,   GRP78/BiP↑, 1,   HSP70/HSPA5↑, 2,  

Autophagy & Lysosomes(tgid=9)

ATG5↑, 1,   LC3B↑, 1,   LC3II↑, 1,   p62↑, 1,   TumAuto↓, 1,   TumAuto↑, 1,  

DNA Damage & Repair(tgid=10)

DNAdam↑, 1,   DNArepair↓, 2,   P53?, 1,   P53↑, 1,   cl‑PARP↑, 1,   PCNA↓, 1,  

Cell Cycle & Senescence(tgid=11)

CDK2↓, 1,   CDK4↓, 1,   cycD1/CCND1↓, 2,   P21?, 1,   p‑RB1↓, 1,   TumCCA↑, 4,  

Proliferation, Differentiation & Cell State(tgid=12)

AXIN1↑, 2,   CD133↓, 2,   CSCs↓, 2,   Diff↑, 1,   EMT↓, 3,   EP2↓, 1,   ERK↓, 1,   Gli1↓, 3,   HDAC↓, 1,   HH↓, 7,   mTOR↓, 2,   mTORC1↓, 1,   Nanog↓, 1,   Nestin↓, 1,   NOTCH1↓, 2,   NOTCH3↓, 1,   OCT4↓, 1,   PI3K↓, 3,   Smo↓, 1,   SOX2↓, 1,   STAT3↓, 1,   TumCG↓, 2,   Wnt↓, 5,  

Migration(tgid=13)

CEA↓, 1,   Cofilin↓, 1,   E-cadherin↑, 3,   fascin↓, 1,   GLI2↓, 1,   GLI3↑, 1,   Ki-67↓, 3,   MMPs↓, 2,   N-cadherin↓, 3,   ROCK1↓, 1,   Snail↓, 1,   SOX4↓, 1,   TumCI↓, 4,   TumCMig↓, 3,   TumCP↓, 4,   TumMeta↓, 4,   Vim↓, 2,   Zeb1↓, 2,   β-catenin/ZEB1↓, 4,   β-catenin/ZEB1↑, 1,  

Angiogenesis & Vasculature(tgid=14)

angioG↓, 4,   EPR↑, 2,   Hif1a↓, 2,   Hypoxia↓, 2,   LymphAG↓, 1,   VEGF↓, 2,   VEGFR2/KDR/Flk1↓, 1,  

Barriers & Transport(tgid=15)

BBB↑, 2,   P-gp/ABCB1↓, 4,  

Immune & Inflammatory Signaling(tgid=16)

CD4+↓, 1,   COX2/PTGS2↓, 3,   DCells↓, 1,   HMGB1↓, 1,   IKKα↓, 1,   IL1β↓, 1,   IL1β↑, 1,   IL6↓, 2,   IL8↓, 1,   IL8↑, 1,   Imm↑, 3,   Imm↝, 1,   Inflam↓, 1,   NF-kB↓, 4,   NK cell↑, 1,   p65↓, 1,   PDT+↓, 1,   PGE2↓, 2,   PSA↓, 2,   TNF-α↓, 3,   TNF-α↑, 1,  

Cellular Microenvironment(tgid=17)

pH↝, 1,  

Protein Aggregation(tgid=19)

NLRP3↑, 1,  

Hormonal & Nuclear Receptors(tgid=20)

EstroRS/ERS↑, 1,   testos∅, 1,  

Drug Metabolism & Resistance(tgid=21)

BioAv↓, 1,   ChemoSen↑, 5,   Dose↑, 2,   Dose↝, 19,   eff↑, 6,   eff↝, 1,   Half-Life↓, 1,   Half-Life↝, 1,   MDR1↓, 1,   RadioS↑, 2,   selectivity↑, 4,  

Clinical Biomarkers(tgid=22)

ALAT↓, 1,   BloodF↑, 2,   CA125↓, 1,   CA19-9↓, 1,   CEA↓, 1,   CYFRA21-1↓, 1,   EstroRS/ERS↑, 1,   GutMicro↑, 1,   IL6↓, 2,   Ki-67↓, 3,   PSA↓, 2,  

Functional Outcomes(tgid=23)

AntiCan↑, 2,   antiNeop↑, 2,   AntiTum↑, 4,   cardioP↑, 1,   chemoP↑, 5,   neuroP↓, 1,   neuroP↑, 1,   OS↓, 1,   OS↑, 40,   QoL↑, 5,   radioP↑, 3,   toxicity↓, 3,   toxicity∅, 1,   TumVol↓, 4,   TumVol↑, 1,   TumW↓, 3,  

Infection & Microbiome(tgid=24)

CD8+↑, 2,  
Total Targets: 189

Pathway results for Effect on Normal Cells:


NA, unassigned(tgid=0)

SpO2↑, 1,  

Redox & Oxidative Stress(tgid=1)

antiOx↑, 8,   Catalase↑, 2,   Fenton↓, 1,   GPx↑, 1,   GSH↑, 1,   HO-1↑, 1,   lipid-P↓, 2,   MDA↓, 2,   MDA↑, 1,   MPO↓, 1,   NFE2L2↓, 1,   NOX4↓, 1,   NRF2↑, 3,   RNS↓, 1,   ROS↓, 11,   SOD↑, 2,   TBARS↓, 1,   VitE↓, 1,  

Mitochondria & Bioenergetics(tgid=3)

PGC-1α↑, 1,  

Core Metabolism/Glycolysis(tgid=4)

ALAT∅, 1,   CREB↑, 1,   NADPH↓, 1,   PPARα↑, 1,  

Cell Death(tgid=5)

Akt↑, 1,   Apoptosis↓, 2,   Bcl-2↑, 1,   Bcl-xL↑, 1,   Casp3↓, 2,   Casp9↓, 1,   Cyt‑c↑, 1,  

Transcription & Epigenetics(tgid=7)

AntiThr↑, 1,   other↑, 3,   tumCV↓, 1,  

DNA Damage & Repair(tgid=10)

DNAdam↓, 1,  

Proliferation, Differentiation & Cell State(tgid=12)

PI3K↑, 1,   STAT3↑, 1,  

Migration(tgid=13)

AntiAg↑, 1,   APP↓, 1,   Ca+2↓, 1,   Treg lymp↝, 1,   TumCI↓, 1,   TumCMig↓, 1,   TumCP↓, 1,  

Angiogenesis & Vasculature(tgid=14)

NO↓, 1,  

Barriers & Transport(tgid=15)

BBB↑, 3,  

Immune & Inflammatory Signaling(tgid=16)

CD25+↑, 1,   CD4+↑, 1,   FOXP3↑, 1,   HMGB1↓, 1,   IL10↑, 1,   IL12↓, 1,   IL1β↓, 1,   IL23↓, 1,   IL4↑, 1,   IL6↓, 3,   Inflam↓, 9,   JAK2↑, 1,   M2 MC↑, 1,   MCP1/CCL2↓, 1,   NF-kB↓, 3,   PGE2↓, 1,   TNF-α↓, 3,  

Cellular Microenvironment(tgid=17)

NOX↓, 1,  

Synaptic & Neurotransmission(tgid=18)

BDNF↑, 1,   p‑tau↓, 1,  

Protein Aggregation(tgid=19)

NLRP3↓, 1,  

Drug Metabolism & Resistance(tgid=21)

Dose↓, 1,   Dose↑, 1,   Dose↝, 1,   eff↑, 4,   Half-Life↝, 1,  

Clinical Biomarkers(tgid=22)

ALAT∅, 1,   AST↓, 1,   AST∅, 1,   IL6↓, 3,  

Functional Outcomes(tgid=23)

cardioP↑, 1,   cognitive↑, 4,   hepatoP↑, 1,   memory↑, 2,   memory∅, 1,   motorD↑, 1,   neuroP↑, 5,   OS↑, 9,   Strength↑, 1,   toxicity?, 1,   toxicity↓, 4,   toxicity↝, 1,   toxicity∅, 2,   Weight↑, 1,  

Infection & Microbiome(tgid=24)

AntiFungal↑, 2,  
Total Targets: 91

Scientific Paper Hit Count for: OS, overall survival
18 Chemotherapy
17 Magnetic Fields
15 Magnetic Field Rotating
14 Vitamin C (Ascorbic Acid)
14 Hydrogen Gas
13 Radiotherapy/Radiation
9 diet Methionine-Restricted Diet
8 Silver-NanoParticles
8 Hyperthermia
8 immunotherapy
8 beta-glucans
8 Dichloroacetate
8 Selenium
7 Curcumin
7 diet Plant based
7 itraconazole
6 Alpha-Lipoic-Acid
6 capecitabine
5 HydroxyCitric Acid
5 cetuximab
5 diet FMD Fasting Mimicking Diet
5 Melatonin
5 Bicarbonate(Sodium)
5 Phenylbutyrate
4 Bevacizumab (brand Avastin)
4 EGCG (Epigallocatechin Gallate)
4 Gemcitabine (Gemzar)
4 Fucoidan
4 Phenethyl isothiocyanate
4 Ramucirumab (CYRAMZA)
4 Selenite (Sodium)
3 3-bromopyruvate
3 almonertinib
3 Anti-oxidants
3 Aspirin
3 Arsenic trioxide
3 Atorvastatin
3 Carvacrol
3 Oxygen, Hyperbaric
3 Quercetin
3 Exercise
3 diet Short Term Fasting
3 Honokiol
3 Inositol
3 IP6 (Inositol 1,2,3,4,5,6-hexakisphosphate)
3 iodine
3 Juglone
3 nivolumab
3 metronomic chemo
3 nicotinamide adenine dinucleotide
3 Sulfasalazine
3 Silymarin (Milk Thistle) silibinin
3 Shikonin
3 Urolithin
2 Lycopene
2 low dose naltrexone
2 Acetyl-l-carnitine
2 Apigenin (mainly Parsley)
2 Ashwagandha(Withaferin A)
2 Bufalin/Huachansu
2 Bifidobacterium
2 Docetaxel
2 Chlorogenic acid
2 chaetocin
2 Choline
2 Citric Acid
2 Calorie Restriction Mimetics
2 Resveratrol
2 Spermidine
2 diet Fermented Foods
2 Sulforaphane (mainly Broccoli)
2 Disulfiram
2 eicosapentaenoic acid
2 Orlistat
2 hydroxychloroquine
2 imatinib
2 isoflavones
2 Lapatinib
2 Lactoferrin/Talactoferrin
2 ipilimumab
2 Metformin
2 Propolis -bee glue
2 Piperine
2 doxorubicin
2 EMF
2 Thymoquinone
2 VitK3,menadione
1 2-DeoxyGlucose
1 Auranofin
1 Astragalus
1 Akkermansia
1 Baicalein
1 Berberine
1 Brucea javanica
1 Bacopa monnieri
1 Boron
1 Butyrate
1 Caffeine
1 Caffeic Acid Phenethyl Ester (CAPE)
1 Sorafenib (brand name Nexavar)
1 Cannabidiol
1 Celastrol
1 chitosan
1 Chocolate
1 Chrysin
1 Coenzyme Q10
1 Hydroxycinnamic-acid
1 Artemisinin
1 Dasatinib/Phyrago
1 Cisplatin
1 salinomycin
1 Deguelin
1 Bortezomib
1 diet Ketogenic
1 D-limonene
1 Copper and Cu NanoParticles
1 Echinacea
1 Emodin
1 Electrical Pulses
1 Folic Acid, Vit B9
1 Formononetin
1 Garcinol
1 Geraniol
1 5-fluorouracil
1 Ginkgolide B
1 Gossypol/AT-101
1 Paclitaxel/Taxol
1 Isoliquiritigenin
1 Isovitexin
1 Vitexin
1 Trastuzumab
1 Licochalcone A
1 Luteolin
1 Mung Bean Sprouts
1 mebendazole
1 Magnesium
1 Mistletoe/Viscum album Extracts
1 Helleborus niger extracts – Christmas Rose
1 Naringin
1 Noscapine
1 Piperlongumine
1 Radio Frequency
1 Shankhpushpi
1 Iron
1 Salvia miltiorrhiza
1 tetrathiomolybdate
1 Tumor Treating Fields
1 Turmerones
1 Vitamin B1/Thiamine
1 Vitamin K2
1 Xylitol
Query results interpretion may depend on "conditions" listed in the research papers.
Such Conditions may include : 
  -low or high Dose
  -format for product, such as nano of lipid formations
  -different cell line effects
  -synergies with other products 
  -if effect was for normal or cancerous cells
Filter Conditions: Pro/AntiFlg:%  IllCat:%  CanType:%  Cells:%  prod#:%  Target#:229  State#:%  Dir#:%
wNotes=0 sortOrder:rid,rpid

 

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