TumCMig Cancer Research Results

TumCMig, Tumor cell migration: Click to Expand ⟱
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Tumor cell migration is a critical process in cancer progression and metastasis, which is the spread of cancer cells from the primary tumor to distant sites in the body.
Scientific Papers found: Click to Expand⟱
476- CUR,    The effects of curcumin on proliferation, apoptosis, invasion, and NEDD4 expression in pancreatic cancer
- in-vitro, PC, PATU-8988 - in-vitro, PC, PANC1
TumCMig↓, TumCI↓, Apoptosis↑, NEDD9↓, p‑Akt↓, p‑mTOR↓, PTEN↑, p73↑, β-TRCP↑,
479- CUR,    Curcumin Has Anti-Proliferative and Pro-Apoptotic Effects on Tongue Cancer in vitro: A Study with Bioinformatics Analysis and in vitro Experiments
- in-vitro, Tong, CAL27
TumCP↓, TumCMig↓, Apoptosis↑, TumCCA↑, Bcl-2↓, BAX↑, cl‑Casp3↑,
461- CUR,    Curcumin inhibits prostate cancer progression by regulating the miR-30a-5p/PCLAF axis
- in-vitro, Pca, PC3 - in-vitro, Pca, DU145
TumCP↓, TumCMig↓, TumCI↓, Apoptosis↑, miR-30a-5p↑, PCLAF↓, Bcl-2↓, Casp3↓, BAX↑, cl‑Casp3↑,
405- CUR,  5-FU,    Curcumin activates a ROS/KEAP1/NRF2/miR-34a/b/c cascade to suppress colorectal cancer metastasis
- vitro+vivo, CRC, HCT116
Apoptosis↑, TumCMig↓, NRF2↑, ROS↑, MET↑, miR-34a↑,
480- CUR,    Curcumin exerts its tumor suppressive function via inhibition of NEDD4 oncoprotein in glioma cancer cells
- in-vitro, GBM, SNB19
TumCP↓, TumCMig↓, Apoptosis↑, TumCCA↑, NEDD9↓, NOTCH1↓, p‑Akt↓,
447- CUR,  OXA,    Curcumin reverses oxaliplatin resistance in human colorectal cancer via regulation of TGF-β/Smad2/3 signaling pathway
- vitro+vivo, CRC, HCT116
p‑p65↓, Bcl-2↓, Casp3↑, EMT↓, p‑SMAD2↓, p‑SMAD3↓, N-cadherin↓, TGF-β↓, E-cadherin↑, TumVol↓, TumCMig↓,
456- CUR,    Curcumin Promoted miR-34a Expression and Suppressed Proliferation of Gastric Cancer Cells
- vitro+vivo, GC, SGC-7901
miR-34a↑, TumCP↓, TumCMig↓, TumCI↓, TumCCA↑, Bcl-2↓, CDK4/6↓, cycD1/CCND1↓,
455- CUR,    Curcumin Affects Gastric Cancer Cell Migration, Invasion and Cytoskeletal Remodeling Through Gli1-β-Catenin
- in-vitro, GC, SGC-7901
Shh↓, Gli1↓, FOXM1↓, β-catenin/ZEB1↓, TumCMig↓, Apoptosis↑, TumCCA↑, Wnt↓, EMT↓, E-cadherin↑, Vim↓,
454- CUR,    Curcumin-Induced DNA Demethylation in Human Gastric Cancer Cells Is Mediated by the DNA-Damage Response Pathway
- in-vitro, GC, MGC803
TumCMig↓, TumCP↓, ROS↑, mtDam↑, DNAdam↑, Apoptosis↑, ATR↑, P21↑, p‑P53↑, GADD45A↑, p‑γH2AX↑,
451- CUR,    The effect of Curcumin on multi-level immune checkpoint blockade and T cell dysfunction in head and neck cancer
- vitro+vivo, HNSCC, SCC15 - vitro+vivo, HNSCC, SNU1076 - vitro+vivo, HNSCC, SNU1041
TumCMig↓, TumCG↓, PD-L1↓, PD-L2↓, Galectin-9↓, EMT↓, T-Cell↑, TILs↑, PD-1↓, TIM-3↓, CD4+↓, CD25+↓, FoxP3+↓, E-cadherin↑, CD8+↑, IFN-γ↑,
450- CUR,    Curcumin may be a potential adjuvant treatment drug for colon cancer by targeting CD44
- in-vitro, CRC, HCT116 - in-vitro, CRC, HCT8
TumCP↓, TumCMig↓, CD44↓, CSCs↓,
446- CUR,    The Influence of Curcumin on the Downregulation of MYC, Insulin and IGF-1 Receptors: A Possible Mechanism Underlying the Anti-Growth and Anti-Migration in Chemoresistant Colorectal Cancer Cells
- in-vitro, CRC, SW480
IR↓, IGF-1↓, Myc↓, TumCMig↓, TumCP↓,
133- CUR,    Curcumin inhibits prostate cancer by targeting PGK1 in the FOXD3/miR-143 axis
- in-vitro, Pca, DU145 - in-vitro, Pca, PC3
miR-143↑, PDK1↓, FOXD3↑, TumCP↓, TumCMig↓, *Inflam↓, *antiOx↑, *chemoPv↑, RadioS↑, ChemoSen↑,
158- CUR,    Curcumin-targeting pericellular serine protease matriptase role in suppression of prostate cancer cell invasion, tumor growth, and metastasis
- vitro+vivo, Pca, LNCaP - in-vitro, Pca, PC3
MMP9↓, Matr↓, Inflam↓, antiOx↓, NF-kB↓, COX2↓, iNOS↓, TumCMig↓, TumCI↓,
11- CUR,    Curcumin inhibits hypoxia-induced epithelial‑mesenchymal transition in pancreatic cancer cells via suppression of the hedgehog signaling pathway
- in-vitro, PC, PANC1
HH↓, Shh↓, Smo↓, Gli1↓, N-cadherin↓, E-cadherin↑, Vim↓, TumCP↓, TumCMig↓, TumCI↓, EMT↓, chemoPv↑,
9- CUR,    Curcumin Suppresses Malignant Glioma Cells Growth and Induces Apoptosis by Inhibition of SHH/GLI1 Signaling Pathway in Vitro and Vivo
- vitro+vivo, MG, U87MG - vitro+vivo, MG, T98G
HH↓, Shh↓, Gli1↓, cycD1/CCND1↓, Bcl-2↓, FOXM1↓, Bax:Bcl2↑, TumCP↓, TumCMig↓, Apoptosis↑, TumVol↑, TumCCA↑, Casp3↑, OS↑,
6238- CUSP9,    A phase Ib/IIa trial of 9 repurposed drugs combined with temozolomide for the treatment of recurrent glioblastoma: CUSP9v3
- Trial, GBM, NA
toxicity↓, TrxR↓, ROS↓, TumCI↓, TumCMig↓, TumCA↓, MMP2↓, MMP9↓, COX2↓, ALDH↓, TumAuto↑, P-gp↓, eff↑,
6236- CUSP9,  EP,    Tumor Treating Fields (TTFields) combined with the drug repurposing approach CUSP9v3 induce metabolic reprogramming and synergistic anti-glioblastoma activity in vitro
- in-vitro, GBM, U251
Apoptosis↑, MOMP↓, Casp2↑, Bcl-2↓, Mcl-1↓, eff↑, OCR↓, OXPHOS↓, TumCMig↓,
6234- CUSP9,    In Vitro and Clinical Compassionate Use Experiences with the Drug-Repurposing Approach CUSP9v3 in Glioblastoma
- Human, GBM, NA
TumCP↓, Apoptosis↑, TumCMig↓, tumCV↓, TumCG↓, cl‑Casp3↑,
6255- Cyste,    Cysteamine Suppresses Cancer Cell Invasion and Migration in Glioblastoma through Inhibition of Matrix Metalloproteinase Activity
- in-vitro, GBM, NA
MMPs↓, MMP2↓, MMP9↓, MMP14↓, TumCI↓, TumCMig↓, Dose↓,
1445- Deg,    Deguelin--an inhibitor to tumor lymphangiogenesis and lymphatic metastasis by downregulation of vascular endothelial cell growth factor-D in lung tumor model
- in-vivo, lymphoma, NA - in-vitro, lymphoma, NA
Akt↓, TumCP↓, TumCMig↓, VEGF↓, TumCG↓, OS↑,
1446- Deg,    Efficacy and mechanism of action of Deguelin in suppressing metastasis of 4T1 cells
- in-vitro, BC, 4T1
cMET↓, p‑ERK↓, p‑Akt↓, TumCMig↓, TumCG↓, Weight∅, *toxicity∅, Hif1a↓, TumMeta↓,
19- Deg,    Deguelin inhibits proliferation and migration of human pancreatic cancer cells in vitro targeting hedgehog pathway
- in-vitro, PC, Bxpc-3 - in-vitro, PC, PANC1
HH↓, Gli1↓, PTCH1↓, Sufu↓, MMP2↓, MMP9↓, PI3K/Akt↓, HIF-1↓, VEGF↓, IKKα↓, NF-kB↓, EMT↓, AMPK↑, mTOR↓, survivin↓, TumCG↓, Apoptosis↑, TumCMig↓, TumCI↓,
1109- DHA,    DHA inhibits Gremlin-1-induced epithelial-to-mesenchymal transition via ERK suppression in human breast cancer cells
- in-vitro, BC, NA
GREM1↓, TumCMig↓, p‑ERK↓, EMT↓,
5071- dietSTF,    Unraveling the impact of intermittent fasting in cancer prevention, mitigation, and treatment: A narrative review
- Review, Var, NA - Review, AD, NA
Risk↓, TumCMig↓, IGF-1↓, TumAuto↑, Inflam↓, ChemoSen↑, Apoptosis↑, chemoP↑, *glucose↓, *AntiDiabetic↑, *cardioP↑, *LDL↓, *BP↓, *neuroP↑, *cognitive↑, *memory↑, *OS↑, *QoL↑, Imm↑, TumCG↓, ChemoSideEff↓, QoL↑,
6281- DL,    Applications of Limonene in Neoplasms and Non-Neoplastic Diseases
- Review, Var, NA - Review, AD, NA - Review, Diabetic, NA
*antiOx↑, AntiTum↑, *AntiDiabetic↑, *neuroP↑, *GastroP↑, *ROS↓, *toxicity↓, *BioAv↑, ChemoSen↑, BAX↑, P53↓, Bcl-2↓, iNOS↓, COX2↓, eff↑, ROS↑, TumCCA↑, cycD1/CCND1↓, CycB/CCNB1↓, TumCMig↓, *lipid-P↓, *GSH↑, *SOD↑, *GPx↑, *hepatoP↑, *glucose↓, *AGEs↓, *Obesity↓, *Aβ↓, *AChE↓,
6343- DRE,    Dandelion root extract affects ESCC progression via regulating multiple signal pathways
- vitro+vivo, ESCC, NA
*Inflam↓, TumCG↓, TumCP↓, TumCMig↓, TumCI↓, Apoptosis↓, TumCG↓, PI3K↓, p‑Akt↓, RAS↓, Raf↓, p‑ERK↓, Bcl-2↓, BAX↑,
6348- DRE,    New prospects in oncotherapy: bioactive compounds from Taraxacum officinale
- Review, Var, NA
Dose↝, TumCP↓, toxicity↓, *AntiDiabetic↑, *antiOx↑, *hepatoP↑, *diuretic↑, *Inflam↓, *neuroP↑, *Imm↑, eff↑, Apoptosis↑, tumCV↓, selectivity↑, TumCMig↓, EMT↓, MMP2↓, MMP9↓, Wnt↓, β-catenin/ZEB1↓, PI3K↓, Akt↓, JNK↓, ERK↓,
6350- DRE,    Tracking Evidences of Dandelion for the Treatment of Cancer: From Chemical Composition, Bioactivity, Signaling Pathways in Cancer Cells to Perspective Study
- Review, Var, NA
AntiCan↑, *Bacteria↓, *Inflam↓, *antiOx↑, TumCCA↑, Apoptosis↑, MOMP↑, Cyt‑c↑, APAF1↑, Casp9↑, Casp3↑, MMP↓, Bcl-2↓, TumCMig↓, TumCI↓, Wnt↓, β-catenin/ZEB1↓, MMP2↓, MMP9↓, TumAuto↑, mTOR↓, 4E-BP1↓, Glycolysis↓, angioG↓,
6326- DRE,  MT,    Taraxacum officinale extract shows antitumor effects on pediatric cancer cells and enhance mistletoe therapy
- in-vitro, neuroblastoma, SH-SY5Y
selectivity↑, Apoptosis↑, MMP↓, TumCI↓, TumCMig↓, eff↑,
6318- DRE,    Dandelion root extract affects colorectal cancer proliferation and survival through the activation of multiple death signalling pathways
- vitro+vivo, CRC, HCT116 - NA, Nor, NCM460
TumCD↑, Apoptosis↑, Casp8↑, selectivity↑, TumCMig↓, selectivity↑, Dose↝, toxicity↓, TumCG↓, MMP↓, mt-ROS↑, *ROS↓, BID↑, Bcl-2↓, PARP↓, NF-kB↑, *NF-kB↓, Casp1↑, *Casp1↓, COX2↑, OXPHOS↓, ETC↓,
6321- DRE,    Dandelion root extract suppressed gastric cancer cells proliferation and migration through targeting lncRNA-CCAT1
- in-vitro, GC, NA
CCAT1↓, TumCP↓, TumCMig↓,
6360- DRE,    Dandelion Seed Extract Affects Tumor Progression and Enhances the Sensitivity of Cisplatin in Esophageal Squamous Cell Carcinoma
- in-vitro, ESCC, KYSE450 - in-vitro, ESCC, Eca109
TumCG↓, TumCP↓, TumCMig↓, TumCI↓, angioG↓, Apoptosis↑, PI3K↓, Akt↓, p‑Akt↓, survivin↓, Bax:Bcl2↑, Casp3↑, Casp9↑, MMP2↓, MMP9↓, VEGF↓, EMT↓, eff↑, DNAdam↑, p‑STAT3↑, ChemoSen↑,
6361- DRE,    Taraxacum officinale Seed Extract Inhibits HeLa Cell Migration at Sub-cytotoxic Concentrations
- in-vitro, Cerv, HeLa
tumCV↓, TumCMig↓,
6363- DRE,    Therapeutic Potential of Dandelion (Taraxacum officinale) Root Extract in Colon Cancer: A Comprehensive Review
- in-vitro, CRC, NA
Apoptosis↑, *Inflam↓, TLR4↓, NF-kB↓, *GutMicro↑, mtDam↑, *ROS↓, Casp1↑, TNF-α↑, Bcl-2↓, PARP↓, MMP↓, Cyt‑c↓, Casp3↑, TumVol↓, COX2↓, iNOS↓, ROS↑, selectivity↑, TumCMig↓, TumCI↓, ER Stress↑, PERK↑, eIF2α↑, ATF4↑, CHOP↑, TumCCA↑, cycD1/CCND1↓, P21↓, P53↑, BioAv↝, Half-Life↝,
4916- DSF,  Cu,    The immunomodulatory function and antitumor effect of disulfiram: paving the way for novel cancer therapeutics
- Review, Var, NA
TumCP↓, TumCMig↓, TumCI↓, eff↑, Imm↑, ROS↑, NF-kB↓, chemoP↑, JNK↑, FOXO↑, Myc↑, TumCCA↑, Apoptosis↑, RadioS↑, PD-L1↑, eff↑, CSCs↓, Dose↝, Half-Life↑,
5008- DSF,  Cu,    Overcoming the compensatory elevation of NRF2 renders hepatocellular carcinoma cells more vulnerable to disulfiram/copper-induced ferroptosis
- in-vitro, HCC, NA
selectivity↑, TumCD↑, TumCMig↓, TumCI↓, angioG↓, mtDam↑, Iron↑, lipid-P↑, Ferroptosis↑, NF-kB↑, p‑p62↑, Keap1↓, eff↑, eff↓, ChemoSen↑,
4832- EA,    Experimental Evidence of the Antitumor, Antimetastatic and Antiangiogenic Activity of Ellagic Acid
*antiOx↑, *AntiCan↑, TumCMig↓, angioG↓, ChemoSen↑, RadioS↑, *chemoP↑, *BioAv↓, eff↓, selectivity↑, MMP2↓, MMP9↓, VEGF↓, TumCCA↑, Apoptosis↑, ROS↑, BioAv↑,
1618- EA,    A comprehensive review on Ellagic acid in breast cancer treatment: From cellular effects to molecular mechanisms of action
- Review, BC, NA
TumCCA↑, TumCMig↓, TumCI↓, TumMeta↓, Apoptosis↑, TGF-β↓, SMAD3↓, CDK6↓, PI3K↓, Akt↓, angioG↓, VEGFR2↓, MAPK↓, NEDD9↓, NF-kB↓, eff↑, eff↑, RadioS↑, ChemoSen↑, DNAdam↑, eff↑, *toxicity∅, *toxicity∅,
1111- EDM,    Evodiamine exerts inhibitory roles in non‑small cell lung cancer cell A549 and its sub‑population of stem‑like cells
- in-vitro, Lung, A549
TumCP↓, TumCMig↓, TumCI↓, EMT↓,
1072- EGCG,    Epigallocatechin gallate (EGCG) suppresses epithelial-Mesenchymal transition (EMT) and invasion in anaplastic thyroid carcinoma cells through blocking of TGF-β1/Smad signaling pathways
- in-vitro, Thyroid, 8505C
EMT↓, TumCI↓, TumCMig↓, TGF-β↓, p‑SMAD2↓, p‑SMAD3↓, SMAD4↓,
22- EGCG,    Inhibition of sonic hedgehog pathway and pluripotency maintaining factors regulate human pancreatic cancer stem cell characteristics
- in-vitro, PC, CD133+ - in-vitro, PC, CD44+ - in-vitro, PC, CD24+ - in-vitro, PC, ESA+
HH↓, Smo↓, PTCH1↓, PTCH2↓, Gli1↓, GLI2↓, Gli↓, Bcl-2↓, XIAP↓, Shh↓, survivin↓, Casp3↑, Casp7↑, CSCs↓, Nanog↓, cMyc↓, OCT4↓, EMT↓, Snail↓, Slug↓, Zeb1↓, TumCMig↓, TumCI↓, eff↑,
665- EGCG,    Anticancer effects of epigallocatechin-3-gallate nanoemulsion on lung cancer cells through the activation of AMP-activated protein kinase signaling pathway
- in-vitro, NA, H1299
AMPK↑, TumCP↓, TumCMig↓, TumCI↓,
651- EGCG,    Epigallocatechin-3-Gallate Therapeutic Potential in Cancer: Mechanism of Action and Clinical Implications
ROS↑, p‑AMPK↑, mTOR↓, FAK↓, Smo↓, Gli1↓, HH↓, TumCMig↓, TumCI↓, NOTCH↓, JAK↓, STAT↓, Bcl-2↓, Bcl-xL↓, BAX↑, Casp9↑,
688- EGCG,  GEM,    Epigallocatechin-3-Gallate (EGCG) Suppresses Pancreatic Cancer Cell Growth, Invasion, and Migration partly through the Inhibition of Akt Pathway and Epithelial–Mesenchymal Transition: Enhanced Efficacy When Combined with Gemcitabine
- in-vitro, PC, NA
Zeb1↓, β-catenin/ZEB1↓, Vim↓, Akt↓, p‑IGFR↓, TumCG↓, TumCMig↓, TumCI↓,
4685- EGCG,    Epigallocathechin gallate, polyphenol present in green tea, inhibits stem-like characteristics and epithelial-mesenchymal transition in nasopharyngeal cancer cell lines
- in-vitro, NPC, TW01 - in-vitro, NPC, TW06
CSCs↓, EMT↓, TumCMig↓, TumCI↓, OCT4↓, Snail↓, Vim↓, E-cadherin↓, HSP70/HSPA5↓, HSP90↓, AntiTum↓,
1247- EMD,    Emodin exerts antitumor effects in ovarian cancer cell lines by preventing the development of cancer stem cells via epithelial mesenchymal transition
- vitro+vivo, Ovarian, SKOV3 - in-vitro, Ovarian, A2780S
TumCP↓, TumCMig↓, TumCI↓, EMT↓, N-cadherin↓, Vim↓, E-cadherin↑, TumCG↓, CD133↓, OCT4↓, CSCs↓,
1319- EMD,    Emodin treatment of papillary thyroid cancer cell lines in vitro inhibits proliferation and enhances apoptosis via downregulation of NF‑κB and its upstream TLR4 signaling
- in-vitro, Thyroid, TPC-1 - in-vitro, Thyroid, IHH4
NF-kB↓, TLR4↓, TumCI↓, TumCMig↓,
2455- erastin,    Discovery of the Inhibitor Targeting the SLC7A11/xCT Axis through In Silico and In Vitro Experiments
- in-vitro, Cerv, HeLa
xCT↓, GSH↓, ROS↑, TumCMig↓,
6338- Eug,    Tumor suppressive roles of eugenol in human lung cancer cells
- in-vitro, Lung, A549
tumCV↓, TumCMig↓, TumCI↓, Akt↓, MMP2↓, *lipid-P↓, *COX2↓, *ROS↓, PI3K↓,

Showing Research Papers: 151 to 200 of 398
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* indicates research on normal cells as opposed to diseased cells
Total Research Paper Matches: 398

Pathway results for Effect on Cancer / Diseased Cells:


Redox & Oxidative Stress ⓘ

antiOx↓, 1,   Ferroptosis↑, 1,   GSH↓, 1,   Iron↑, 1,   Keap1↓, 1,   lipid-P↑, 1,   NRF2↑, 1,   OXPHOS↓, 2,   ROS↓, 1,   ROS↑, 8,   mt-ROS↑, 1,   TrxR↓, 1,   xCT↓, 1,  

Mitochondria & Bioenergetics ⓘ

ETC↓, 1,   MMP↓, 4,   mtDam↑, 3,   OCR↓, 1,   Raf↓, 1,   XIAP↓, 1,  

Core Metabolism/Glycolysis ⓘ

AMPK↑, 2,   p‑AMPK↑, 1,   cMyc↓, 1,   Glycolysis↓, 1,   IR↓, 1,   PDK1↓, 1,   PI3K/Akt↓, 1,  

Cell Death ⓘ

Akt↓, 6,   p‑Akt↓, 5,   APAF1↑, 1,   Apoptosis↓, 1,   Apoptosis↑, 21,   BAX↑, 5,   Bax:Bcl2↑, 2,   Bcl-2↓, 13,   Bcl-xL↓, 1,   BID↑, 1,   Casp1↑, 2,   Casp2↑, 1,   Casp3↓, 1,   Casp3↑, 6,   cl‑Casp3↑, 3,   Casp7↑, 1,   Casp8↑, 1,   Casp9↑, 3,   Cyt‑c↓, 1,   Cyt‑c↑, 1,   Ferroptosis↑, 1,   iNOS↓, 3,   JNK↓, 1,   JNK↑, 1,   MAPK↓, 1,   Mcl-1↓, 1,   MOMP↓, 1,   MOMP↑, 1,   Myc↓, 1,   Myc↑, 1,   survivin↓, 3,   TumCD↑, 2,   β-TRCP↑, 1,  

Kinase & Signal Transduction ⓘ

FOXD3↑, 1,  

Transcription & Epigenetics ⓘ

Matr↓, 1,   miR-143↑, 1,   miR-30a-5p↑, 1,   tumCV↓, 4,  

Protein Folding & ER Stress ⓘ

CHOP↑, 1,   eIF2α↑, 1,   ER Stress↑, 1,   HSP70/HSPA5↓, 1,   HSP90↓, 1,   PERK↑, 1,  

Autophagy & Lysosomes ⓘ

p‑p62↑, 1,   TumAuto↑, 3,  

DNA Damage & Repair ⓘ

ATR↑, 1,   DNAdam↑, 3,   GADD45A↑, 1,   P53↓, 1,   P53↑, 1,   p‑P53↑, 1,   p73↑, 1,   PARP↓, 2,   PCLAF↓, 1,   p‑γH2AX↑, 1,  

Cell Cycle & Senescence ⓘ

CycB/CCNB1↓, 1,   cycD1/CCND1↓, 4,   P21↓, 1,   P21↑, 1,   TumCCA↑, 11,  

Proliferation, Differentiation & Cell State ⓘ

4E-BP1↓, 1,   ALDH↓, 1,   CD133↓, 1,   CD44↓, 1,   cMET↓, 1,   CSCs↓, 5,   EMT↓, 13,   ERK↓, 1,   p‑ERK↓, 3,   FOXM1↓, 2,   FOXO↑, 1,   Gli↓, 1,   Gli1↓, 6,   GREM1↓, 1,   HH↓, 5,   IGF-1↓, 2,   p‑IGFR↓, 1,   miR-34a↑, 2,   mTOR↓, 3,   p‑mTOR↓, 1,   Nanog↓, 1,   NOTCH↓, 1,   NOTCH1↓, 1,   OCT4↓, 3,   PI3K↓, 5,   PTCH1↓, 2,   PTCH2↓, 1,   PTEN↑, 1,   RAS↓, 1,   Shh↓, 4,   Smo↓, 3,   STAT↓, 1,   p‑STAT3↑, 1,   Sufu↓, 1,   TumCG↓, 12,   Wnt↓, 3,  

Migration ⓘ

CCAT1↓, 1,   CDK4/6↓, 1,   E-cadherin↓, 1,   E-cadherin↑, 5,   FAK↓, 1,   Galectin-9↓, 1,   GLI2↓, 1,   MET↑, 1,   MMP14↓, 1,   MMP2↓, 8,   MMP9↓, 8,   MMPs↓, 1,   N-cadherin↓, 3,   NEDD9↓, 3,   Slug↓, 1,   p‑SMAD2↓, 2,   SMAD3↓, 1,   p‑SMAD3↓, 2,   SMAD4↓, 1,   Snail↓, 2,   TGF-β↓, 3,   TumCA↓, 1,   TumCI↓, 26,   TumCMig↓, 50,   TumCP↓, 20,   TumMeta↓, 2,   Vim↓, 5,   Zeb1↓, 2,   β-catenin/ZEB1↓, 4,  

Angiogenesis & Vasculature ⓘ

angioG↓, 5,   ATF4↑, 1,   HIF-1↓, 1,   Hif1a↓, 1,   VEGF↓, 4,   VEGFR2↓, 1,  

Barriers & Transport ⓘ

P-gp↓, 1,  

Immune & Inflammatory Signaling ⓘ

CD25+↓, 1,   CD4+↓, 1,   COX2↓, 4,   COX2↑, 1,   FoxP3+↓, 1,   IFN-γ↑, 1,   IKKα↓, 1,   Imm↑, 2,   Inflam↓, 2,   JAK↓, 1,   NF-kB↓, 6,   NF-kB↑, 2,   p‑p65↓, 1,   PD-1↓, 1,   PD-L1↓, 1,   PD-L1↑, 1,   PD-L2↓, 1,   T-Cell↑, 1,   TILs↑, 1,   TLR4↓, 2,   TNF-α↑, 1,  

Cellular Microenvironment ⓘ

TIM-3↓, 1,  

Hormonal & Nuclear Receptors ⓘ

CDK6↓, 1,  

Drug Metabolism & Resistance ⓘ

BioAv↑, 1,   BioAv↝, 1,   ChemoSen↑, 7,   Dose↓, 1,   Dose↝, 3,   eff↓, 2,   eff↑, 13,   Half-Life↑, 1,   Half-Life↝, 1,   RadioS↑, 4,   selectivity↑, 7,  

Clinical Biomarkers ⓘ

FOXM1↓, 2,   Myc↓, 1,   Myc↑, 1,   PD-L1↓, 1,   PD-L1↑, 1,  

Functional Outcomes ⓘ

AntiCan↑, 1,   AntiTum↓, 1,   AntiTum↑, 1,   chemoP↑, 2,   chemoPv↑, 1,   ChemoSideEff↓, 1,   OS↑, 2,   QoL↑, 1,   Risk↓, 1,   toxicity↓, 3,   TumVol↓, 2,   TumVol↑, 1,   Weight∅, 1,  

Infection & Microbiome ⓘ

CD8+↑, 1,  
Total Targets: 212

Pathway results for Effect on Normal Cells:


NA, unassigned ⓘ

diuretic↑, 1,  

Redox & Oxidative Stress ⓘ

antiOx↑, 5,   GPx↑, 1,   GSH↑, 1,   lipid-P↓, 2,   ROS↓, 4,   SOD↑, 1,  

Core Metabolism/Glycolysis ⓘ

glucose↓, 2,   LDL↓, 1,  

Cell Death ⓘ

Casp1↓, 1,  

Barriers & Transport ⓘ

GastroP↑, 1,  

Immune & Inflammatory Signaling ⓘ

COX2↓, 1,   Imm↑, 1,   Inflam↓, 5,   NF-kB↓, 1,  

Synaptic & Neurotransmission ⓘ

AChE↓, 1,  

Protein Aggregation ⓘ

AGEs↓, 1,   Aβ↓, 1,  

Drug Metabolism & Resistance ⓘ

BioAv↓, 1,   BioAv↑, 1,  

Clinical Biomarkers ⓘ

BP↓, 1,   GutMicro↑, 1,  

Functional Outcomes ⓘ

AntiCan↑, 1,   AntiDiabetic↑, 3,   cardioP↑, 1,   chemoP↑, 1,   chemoPv↑, 1,   cognitive↑, 1,   hepatoP↑, 2,   memory↑, 1,   neuroP↑, 3,   Obesity↓, 1,   OS↑, 1,   QoL↑, 1,   toxicity↓, 1,   toxicity∅, 3,  

Infection & Microbiome ⓘ

Bacteria↓, 1,  
Total Targets: 37

Scientific Paper Hit Count for: TumCMig, Tumor cell migration
21 Curcumin
13 Quercetin
13 Shikonin
11 Berberine
10 Capsaicin
10 Honokiol
9 Dandelion Root
9 Silymarin (Milk Thistle) silibinin
8 Apigenin (mainly Parsley)
8 Resveratrol
8 EGCG (Epigallocatechin Gallate)
8 Betulinic acid
8 Magnolol
8 Magnetic Fields
8 Sulforaphane (mainly Broccoli)
7 Ashwagandha(Withaferin A)
7 Thymoquinone
7 Urolithin
6 Propolis -bee glue
6 Chlorogenic acid
6 Fisetin
6 Piperlongumine
6 Rosmarinic acid
5 Silver-NanoParticles
5 Alpha-Lipoic-Acid
5 Artemisinin
5 Baicalein
5 Carvacrol
5 Eugenol
5 Metformin
5 Phenethyl isothiocyanate
5 Piperine
4 Astragalus
4 Gemcitabine (Gemzar)
4 Astaxanthin
4 Boron
4 Luteolin
4 Pterostilbene
3 Radiotherapy/Radiation
3 Berbamine
3 Bacopa monnieri
3 brusatol
3 Caffeic acid
3 Chrysin
3 Cinnamon
3 Crocetin
3 Copper and Cu NanoParticles
3 Cucurbitacin
3 CUSP9
3 Deguelin
3 Ferulic acid
3 Garcinol
3 HydroxyTyrosol
3 Lycopene
3 salinomycin
3 Aflavin-3,3′-digallate
2 Allicin (mainly Garlic)
2 Andrographis
2 Arctigenin
2 Baicalin
2 Bufalin/Huachansu
2 Genistein (soy isoflavone)
2 Boswellia (frankincense)
2 Paclitaxel
2 Carnosic acid
2 Celecoxib
2 Celastrol
2 Chlorophyllin
2 Docetaxel
2 5-fluorouracil
2 Disulfiram
2 Ellagic acid
2 Emodin
2 Ginkgo biloba
2 Grapeseed extract
2 Juglone
2 Plumbagin
2 Magnetic Field Rotating
2 Nimbolide
2 Psoralidin
2 Cisplatin
2 Parthenolide
2 Ursolic acid
2 Vitamin C (Ascorbic Acid)
2 VitK3,menadione
1 Auranofin
1 Ajoene (compound of Garlic)
1 dibenzyl trisulphide(DTS) from Anamu
1 Anethole/trans-Anethole
1 Aspirin
1 Atorvastatin
1 Aloe anthraquinones
1 Biochanin A
1 Bevacizumab (brand Avastin)
1 Brucea javanica
1 Bromelain
1 selenomethionine
1 Bruteridin(bergamot juice)
1 Butyrate
1 Caffeic Acid Phenethyl Ester (CAPE)
1 Cannabidiol
1 chitosan
1 Selenium NanoParticles
1 Hydroxycinnamic-acid
1 Citric Acid
1 Oxaliplatin
1 Electrical Pulses
1 Cysteamine
1 Docosahexaenoic Acid
1 diet Short Term Fasting
1 D-limonene
1 Mistletoe
1 Evodiamine
1 erastin
1 Fucoidan
1 Shilajit/Fulvic Acid
1 Gambogic Acid
1 Ginger/6-Shogaol/Gingerol
1 γ-linolenic acid (Borage Oil)
1 Graviola
1 Proanthocyanidins
1 Hydrogen Gas
1 HydroxyCitric Acid
1 Indole-3-carbinol
1 Licorice
1 Melatonin
1 doxorubicin
1 immunotherapy
1 Myricetin
1 Naringin
1 Niclosamide (Niclocide)
1 Oroxylin A
1 Orlistat
1 Propyl gallate
1 temozolomide
1 isoflavones
1 raloxifen
1 tamoxifen
1 Germacranolide
1 Rutin
1 Sanguinarine
1 Sulfasalazine
1 Selenite (Sodium)
1 Thymol-Thymus vulgaris
1 Arsenic trioxide
1 Zinc
1 β‐Elemene
Query results interpretion may depend on "conditions" listed in the research papers.
Such Conditions may include : 
  -low or high Dose
  -format for product, such as nano of lipid formations
  -different cell line effects
  -synergies with other products 
  -if effect was for normal or cancerous cells

Filter Conditions: Pro/AntiFlg:%  IllCat:%  CanType:%  Cells:%  prod#:%  Target#:326  State#:%  Dir#:%
  wNotes=0  sortOrder:rid,rpid

 

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