MDA Cancer Research Results

MDA, Serum malondialdehyde: Click to Expand ⟱
Source:
Type:
MDA : malondialdehyde. The level of oxidative stress can be measured by assessing the MDA levels.
Since MDA is highly cytotoxic and carcinogenic agent it is frequently used as a biomarker of oxidative stress during major health problems such as cancer, etc.
Malondialdehyde (MDA) is the most widely used agent to estimate the extent of lipid peroxidation. Timely diagnosis of the condition followed by supplementation with antioxidants like beta-carotene, pro-vitamin A, vitamin A, vitamin C, vitamin E, lipoic acid, zinc, selenium, and spirulina can prevent potentially malignant disorders.
MDA is a lipid peroxidation marker
Scientific Papers found: Click to Expand⟱
6871- FA,  Sesame,    Nano-encapsulated ferulic acid in sesame protein isolate alleviates acrylamide-induced liver toxicity and genotoxicity in rats via oxidative stress and DNA damage modulation
- in-vivo, Nor, NA
*GSH↑, *GPx↑, *SOD↓, *Catalase↑, *MDA↓, *IL6↓, *TNF-α↑, *DNAdam↓, *hepatoP↑, *BioAv↓, *BioAv↑, CompStab↓,
6877- FA,    The protective role of ferulic acid on sepsis-induced oxidative damage in Wistar albino rats
- in-vivo, Nor, NA
*antiOx↑, *Inflam↓, *AntiCan↑, *hepatoP↑, *DNAdam↓, *Sepsis↓, *MDA↓, *GSH↑, *GPx↑, *ROS↓,
6885- FA,    Mitigation of renal toxicity induced by paraquat using ferulic acid: Role of inflammatory pathways
- in-vivo, Nor, NA
*Dose↝, *TAC↑, *MDA↓, *RenoP↑, *PI3K↓, *Akt↓, *ROS↓, *Inflam↓, PPARγ↝, *NF-kB↓, *IL6↓, *TNF-α↓, *iNOS↓, *ALAT↓, *AST↓, *Urea↓, *Catalase↑, *SOD↑, *GPx↑, *GSH↑,
3714- FA,    Recent Advances in the Neuroprotective Properties of Ferulic Acid in Alzheimer's Disease: A Narrative Review
- Review, AD, NA
*antiOx↑, *Inflam↓, *neuroP↑, *NF-kB↓, *NLRP3↓, *iNOS↓, *COX2/PTGS2↓, *TNF-α↓, *IL1β↓, *VCAM-1↓, *ICAM-1↓, *p‑MAPK↓, *p38↓, *JNK↓, *IL6↓, *IL8↓, *hepatoP↑, *RenoP↑, *Catalase↑, *PPARγ↑, *ROS↓, *Fenton↓, *IronCh↑, *SOD↑, *MDA↓, *lipid-P↓, *NRF2↑, *HO-1↑, *ARE↑, *Bil↑, *radioP↑, *GCLC↑, *GCLM↑, *NQO1↑, *Half-Life↝, *GutMicro↑, *Aβ↓, *BDNF↑, *Ca+2↓, *lipid-P↓, *PGE2↓, *cognitive↑, *ChAT↑, *memory↑, *Dose↝, *toxicity↓,
3778- FA,    Recent Advances in the Neuroprotective Properties of Ferulic Acid in Alzheimer’s Disease: A Narrative Review
- Review, AD, NA
*neuroP↑, *Aβ↓, *antiOx↑, *Inflam↓, *ROS↓, *NF-kB↓, *NLRP3↓, *iNOS↓, *COX2/PTGS2↓, *TNF-α↓, *IL1β↓, *VCAM-1↓, *ICAM-1↓, *p‑MAPK?, *hepatoP↑, *TLR4↓, *PPARγ↑, *NRF2↑, *Fenton↓, *IronCh↑, *MDA↓, *HO-1↑, *Bil↑, *GCLC↑, *GCLM↑, *NQO1↑, *GutMicro↑, *SOD↑, *Ca+2↓, *lipid-P↓, *PGE2↓,
3782- FA,    Ferulic acid ameliorates bisphenol A (BPA)-induced Alzheimer’s disease-like pathology through Akt-ERK crosstalk pathway in male rats
- in-vivo, AD, NA
*cognitive↑, *ERK↓, *p‑Akt↓, *AChE↓, *BACE/β-secretase↓, *neuroP↑, *ROS↓, *MDA↓, *GSH↑, *GSSG↓, *p‑tau↓, *lipid-P↓, *Aβ↓,
6981- Form,    Formononetin: a review of its source, pharmacology, drug combination, toxicity, derivatives, and drug delivery systems
- Review, Var, NA - Review, AD, NA - Review, PSA, NA
BioAv↝, *memory↑, *ROS↓, *AChE↓, *NF-kB↓, *Keap1↝, *NRF2↑, *Inflam↓, *PGC-1α↝, *HO-1↓, *p‑tau↓, *cognitive↑, *BDNF↑, *5HT↑, *Stroke↓, *PARP1↓, *AIF↓, *Casp3↓, NP/CIPN↓, *neuroP↑, *NGF↑, *TNF-α↓, *IL1β↓, *IL18↓, *IL6↓, *VCAM-1↓, *pol-M2 MC↑, *hepatoP↑, *AST↓, *ALAT↓, *LC3II↑, *Beclin-1/ATG6↑, *p62↑, *COX2/PTGS2↑, *MMP↑, *ATP↑, *GSH↑, *Catalase↑, *GPx↑, *MDA↓, *antiPs↑, *AntiDiabetic↑, *glucose↓, *Insulin↑, *GutMicro↑, *Obesity↓, COX2/PTGS2↓, cycD1/CCND1↓, TumCCA↑, EGFR↓, GSK‐3β↑, Mcl-1↓, *toxicity↓, TumCP↓, Hif1a↓, VEGF↓, ERK↓, LAMs↓, Cyt‑c↑, Casp9↑, Casp3↑, PARP↑, TumCD↑, mitA↑, BACH1↓, P53↓, ROS↑, PD-1↓, NF-kB↓, *Bacteria↓, *AntiViral↑, *mt-ROS?, *PI3K↓, *chemoP↑, ChemoSen↑, Synergy↑, *toxicity↓, *BioAv↑, *BioAv↑, *Synergy↑, *antiAll↑,
8585- FS,    Dietary flaxseed: Cardiometabolic benefits and its role in promoting healthy aging
- Review, Nor, NA
*cardioP↑, *Obesity↓, *lipidLev↓, *BP↓, *Inflam↓, *CRP↓, *IL6↓, *ROS↓, *hepatoP↑, *Ingr↝, *GutMicro↑, *Dose↑, *Ingr↝, *Ingr?, *CompStab↝, *MDA↓, *hs-CRP↓, *TNF-α↓, *AntiDiabetic↑, *ALAT↓, *AST↓, *GGT/CD224↓, *TG/TAG↓, *LDL↓, *HDL∅, *TC↓, *glucose↓, *Insulin↓, *SIRT1↑, *Dose↝, *Dose?,
8607- FSO,    Effects of flaxseed oil supplementation on biomarkers of inflammation and oxidative stress in patients with metabolic syndrome and related disorders: A systematic review and meta-analysis of randomized controlled trials
- Review, Obesity, NA
*IL6↓, *MDA↓, *TAC↑,
7012- Fuc,    Fucoidan: A promising natural therapeutic agent for protecting human kidney health
- Review, EC, NA
*RenoP↑, *Inflam↓, *antiOx↑, *ROS↓, *BloodF↑, *diuretic↑, *BioAv↓, *BioAv↑, *MAPK↓, *ERK↑, *NLRP3↓, *NRF2↑, *MDA↓, *SOD↑, *GPx↑, *Catalase↑, *lipid-P↓, *DNAdam↓, *Fibrosis↓, *JAK2↓, *STAT3↓, *uricA↓, *COL1↓, *α-SMA↓, *SIRT1↑, *HO-1↑, *GLP-1R↑, *HMGB1↓, *RAGE↓, *NF-kB↓, *TGF-β1↓, *PI3K↓, *Akt↓, *GutMicro↑, *SCFAs↑, *Buty↑, *IBI↑, *TJ↑, *Dose↝,
7040- GA,    Effects of gallic acid on acrylamide-induced endoplasmic reticulum stress, neuroinflammation and neuronal apoptosis in rats
- Trial, AD, NA
*SOD↑, *GSH↑, *GPx↑, *Catalase↑, *MDA↓, *TNF-α↓, *IL1β↓, *BAX↓, *Casp3↓, *BDNF↑, *NRF2↑, *HO-1↑,
7046- GA,    Gallic acid: A promising anti-non-small cell lung cancer compound targeting early growth response protein-1 for apoptosis and ferroptosis
- in-vitro, NSCLC, A549 - in-vitro, NSCLC, H1299
TumCP↓, TumCCA↑, TumCMig↓, TumCI↓, Apoptosis↑, Ferroptosis↑, THBS1↓, EGR1↓, TGF-β1↓, SMAD2↓, SMAD3↓, GPx4↓, ROS↑, i-MDA↑, i-Iron↑,
3723- GBE,    Can We Use Ginkgo biloba Extract to Treat Alzheimer’s Disease? Lessons from Preclinical and Clinical Studies
- Review, AD, NA
*memory↑, *antiOx↑, *Casp3↓, *APP↓, *AChE↓, *Aβ↓, *5HT↑, *SOD↓, *MDA↓, *NO↓, *GSH↑, *Bcl-2↑, *BAX↑, *TNF-α↓, *IL1β↑, *iNOS↓, *IL10↓, *p‑tau↓, *ROS↓, *MAOB↓, *cognitive↑, *neuroP↑, *Apoptosis↓,
7140- GI,    Benefits of Ginger and Its Constituent 6-Shogaol in Inhibiting Inflammatory Processes
- Review, Var, NA
*Dose↝, *Inflam↓, *COX2/PTGS2↓, *iNOS↓, *NF-kB↓, *MAPK?, *HO-1↑, *PGE2↓, *TNF-α↓, *IL6↓, *IL1β↓, *IFN-γ↓, *MCP1/CCL2↓, *MIP2↓, *RANTES↓, *MPO↓, *NO↓, *Stroke↓, *BrainVol↑, *MDA↓, *ROS↓, *GSH↑, *NRF2↑, *antiOx↑, NLRP3↓, HDAC1↓,
7338- Gra,    Pharmacological Activities of Soursop (Annona muricata Lin.)
- Review, Var, NA
AntiCan↑, *AntiDiabetic↑, *Diar↓, *Bacteria↓, *AntiViral↑, *Wound Healing↑, MMP2↓, MMP9↓, MMP↓, ROS↑, TumCCA↑, BAX↑, Bcl-2↓, Casp3↑, *BAX↓, *MDA↓, *Catalase↑, *SOD↑, *GSH↑, *NO↑, *PGE2↑, *HSP70/HSPA5↑,
841- Gra,    The Chemopotential Effect of Annona muricata Leaves against Azoxymethane-Induced Colonic Aberrant Crypt Foci in Rats and the Apoptotic Effect of Acetogenin Annomuricin E in HT-29 Cells: A Bioassay-Guided Approach
- in-vitro, CRC, HT-29 - in-vitro, Nor, CCD841
PCNA↓, Bcl-2↓, BAX↑, *MDA↓, lipid-P↓, TumCG↓, MMP↓, Cyt‑c↑, Casp3↑, Casp7↑, Casp9↑, *ROS↓, LDH↓, *toxicity↓, selectivity↑,
7482- H2,    Molecular Hydrogen Therapy: Mechanisms, Delivery Methods, Preventive, and Therapeutic Application
- Review, Var, NA - Review, IBD, NA - Review, Stroke, NA - Review, Sepsis, NA - Review, AD, NA
Dose↝, *Inflam↓, *IL1β↓, *IL6↓, *TNF-α↓, *neuroP↑, *mTOR↓, *IL10↑, *TGF-β↑, *Sepsis↓, *NRF2↑, *antiOx↑, *Catalase↑, *SOD↑, *GPx↑, *ROS↓, *HO-1↑, *PI3K↑, *Akt↑, *hepatoP↑, *MPO↓, *cardioP↑, CDK4↓, CDK6↑, CD47↓, PI3K↓, Akt↓, Hif1a↓, selectivity↑, *MMP↑, *ATP↑, *ER Stress↓, *CHOP/DDIT3↓, *Casp12↓, *GRP78/BiP↓, *p38↓, *p‑JNK↓, *LC3‑Ⅱ/LC3‑Ⅰ↑, *p‑eIF2α↓, *ATF4↓, *XBP-1↓, *Imm↑, *IFN-γ↓, *IL4↓, *GranB/GZMB↓, NK cell↑, radioP↑, *CD4+↑, CD8+↑, *Dose↝, *other↑, *Dose↝, *antiPs↑, *BioAv↝, *GutMicro↑, Dose↝, *IBI↑, TumCP↓, TumCI↓, TumCMig↓, CD8+↑, PGC-1α↑, Akt↓, SCD1↓, *MDA↓, Synergy↑, *APP↓, *BACE/β-secretase↓, *Aβ↓, *cognitive↑, *neuroP↑, NP/CIPN↓, *Stroke↓, *NLRP3↓, *ALAT↓, *AST↓, *LPS↓, *hepatoP↑, chemoP↑, *creat↓, *Urea↓, *RenoP↑, *eff↑, Apoptosis↑, XIAP↓, IAP2/BIRC3↓, TumVol↓, MALAT1↓, EZH2↓, miR-124-3p↓, eff↑, ChemoSen↑, *compII↑, *compIII↑, *LDL↓, *Obesity↓, QoL↑, PFS↑, *antiAll↑,
7489- H2,    Molecular Hydrogen in the Treatment of Respiratory Diseases
- Review, Asthma, NA
*antiOx↑, *Inflam↓, *Apoptosis↓, *Dose↓, *Dose↝, *eff↑, *ROS↓, *RNS↓, *NRF2↑, *HO-1↑, *Fenton↓, *NLRP3↓, *NADPH↓, *NOX4↓, *NOX↓, *MPO↓, *NF-kB↓, *TNF-α↓, *IL6↓, *IL1β↓, *HMGB1↓, *IL4↑, *IL10↑, *M2 MC↑, *Treg lymp↝, *Bcl-2↑, *Bcl-xL↑, *PI3K↑, *Akt↑, *JAK2↑, *STAT3↑, *Dose↑, *CD4+↑, *CD25+↑, *FOXP3↑, *MDA↓, *SOD↑, *Catalase↑, *Casp3↓, *Casp9↓, *TBARS↓, *SpO2↑, *VitE↓, *OS↑, *Weight↑, *DNAdam↓, *PGE2↓, *MCP1/CCL2↓, *lipid-P↓, *TumCP↓, *tumCV↓, *TumCMig↓, *TumCI↓, TumW↓, TumVol↓, selectivity↑, QoL↑, ChemoSen↑, chemoP↑, radioP↑, ROS↑, NLRP3↑, Casp3↑, VEGF↓, Wnt↓, β-catenin/ZEB1↓, *antiAll↑,
7492- H2,  Chemo,    Molecular Hydrogen Protects against Various Tissue Injuries from Side Effects of Anticancer Drugs by Reducing Oxidative Stress and Inflammation
- Review, Var, NA
*ROS↓, *antiOx↑, *Inflam↓, *chemoP↑, AntiCan↑, ChemoSen↑, chemoP↑, *BUN↓, *creat↓, *TUNEL↓, *MDA↓, *SOD↑, *Catalase↑, *NRF2↑, *BNP↓, *AST↓, *ALAT↓, *TNF-α↓, *IL1β↓, *IL6↓, *Casp3↓, *Casp9↓, *GPx↑, *E-cadherin↑, *Vim↓, *α-SMA↓, *COL1↓, *cardioP↑, *hepatoP↑, *p‑mTOR↓, *EMT↓, eff∅, *LPS↓, *TLR4↓, radioP↑,
7926- H2,    Hydrogen gas inhalation enhances alveolar macrophage phagocytosis in an ovalbumin-induced asthma model
- in-vivo, Asthma, NA
*Dose↝, *Airway↓, *BALF-Infl↓, *Th2↓, *IL4↓, *IgE↓, *MDA↓, *SOD↑, *NF-kB↓, *NRF2↑, *antiAll↑,
7925- H2,    Inhalation of hydrogen gas attenuates airway inflammation and oxidative stress in allergic asthmatic mice
- in-vivo, Asthma, NA
*Dose?, *IL4↓, *IL13↓, *TNF-α↓, *CXCL15↓, *SOD↑, *MDA↓, *MPO↓, *ROS↓, *antiOx↑, *Inflam↓, *Apoptosis↓, *toxicity↓, *Stroke↓, *Airway↓, *Neut↓, *Eos↓, *BALF-Lym↓, *BALF-Infl↓, *AirwayM↓, *antiAll↑,
7933- H2,    Hydrogen inhalation ameliorates lung inflammation in mice with asthma
- in-vivo, Asthma, NA
*antiOx↑, *Inflam↓, *IL4↓, *IL5↓, *IL13↓, *IL10↑, *TGF-β1↑, *IgE↓, *MDA↓, *SOD↑, *Airway↓, *antiAll↑,
3771- H2,    Molecular Hydrogen Neuroprotection in Post-Ischemic Neurodegeneration in the Form of Alzheimer’s Disease Proteinopathy: Underlying Mechanisms and Potential for Clinical Implementation—Fantasy or Reality?
- Review, AD, NA - Review, Stroke, NA
*cognitive↑, AntiCan↑, *Inflam↓, *antiOx↑, *ROS↓, *neuroP↑, *SOD↑, *GPx↑, *MDA↑, *BBB↑, *OS↑, *Ca+2↓, *APP↓, *p‑tau↓,
3770- H2,    Role of Molecular Hydrogen in Ageing and Ageing-Related Diseases
- Review, AD, NA - Review, Park, NA
*antiOx↑, *NRF2↑, *HO-1↑, *Inflam↓, *neuroP↑, *cardioP↑, *other↓, *ROS↓, *NADPH↓, *Catalase↑, *GPx1↑, *NO↓, *mt-ROS↓, *SIRT3↑, *SIRT1↑, *TLR4↓, *mTOR↓, *cognitive↑, *Sepsis↓, *PTEN↓, *Akt↓, *NLRP3↓, *AntiAg↑, *IL6↓, *TNF-α↓, *IL1β↓, *MDA↓, *memory↑, *FOXO3↑, TumCG↓, *LDL↓,
3764- H2,    Therapeutic Effects of Hydrogen Gas Inhalation on Trimethyltin-Induced Neurotoxicity and Cognitive Impairment in the C57BL/6 Mice Model
- in-vivo, AD, NA
*memory↑, *Aβ↓, *p‑tau↓, *BAX↓, *ROS↓, *NO↓, *Ca+2↓, *MDA↓, *Catalase↓, *GPx↓, *TNF-α↓, *Bcl-2↑, *VEGF↑, *Inflam↓, *cognitive↑,
3767- H2,    The role of hydrogen therapy in Alzheimer's disease management: Insights into mechanisms, administration routes, and future challenges
- Review, AD, NA
*Inflam↓, *neuroP↑, *toxicity↓, *antiOx↑, *ROS↓, *NLRP3↓, *IL1β↓, *mtDam↓, *ATP↑, *AMPK↑, *FOXO3↑, *SOD1↑, *Catalase↑, *NRF2↑, *NO↓, *MDA↓, *lipid-P↓, *memory↑, *ER(estro)↓, *BDNF↑, *cognitive↑, *APP↓, *BACE/β-secretase↓, *Aβ↓, *BP∅, *BBB↑,
2525- H2,    Hydrogen-Rich Saline Attenuates Cardiac and Hepatic Injury in Doxorubicin Rat Model by Inhibiting Inflammation and Apoptosis
- in-vivo, Var, NA
OS↓, cardioP↑, *AST↓, ALAT↓, *ROS↓, *MDA↓, *hepatoP↑, *Inflam↓, chemoP↑,
1633- HCA,    Hydroxycitric Acid Alleviated Lung Ischemia-Reperfusion Injury by Inhibiting Oxidative Stress and Ferroptosis through the Hif-1α Pathway
- in-vivo, NA, NA - in-vitro, Nor, HUVECs
*other↓, *Inflam↓, *MDA↓, *ROS↓, *Iron↓, *SOD↓, *Hif1a↓, *HO-1↓,
1635- HCA,    Hydroxycitric acid prevents hyperoxaluric-induced nephrolithiasis and oxidative stress via activation of the Nrf2/Keap1 signaling pathway
- vitro+vivo, Nor, NA
*other↓, *ROS↓, *SOD↑, *Catalase↑, *MDA↓, *NRF2↑,
4213- Hup,    Huperzine A-Liposomes Efficiently Improve Neural Injury in the Hippocampus of Mice with Chronic Intermittent Hypoxia
- in-vivo, AD, NA
*cognitive↑, *SOD↑, *GPx↑, *MDA↓, *ROS↓, *Iron↓, *TfR1/CD71↓, *FTL↓, *ERK↑, *PKA↑, *CREB↑, *BDNF↑, *PSD95↑, *neuroP↑,
7565- HYP,    Potential Implications of Hyperoside on Oxidative Stress-Induced Human Diseases: A Comprehensive Review
- Review, AD, NA
*Inflam↓, *antiOx↑, *neuroP↑, *lipid-P↓, *ROS↓, *IL1β↓, *IL6↓, *IL8↓, *TNF-α↓, *MDA↓, *BAX↓, *Casp3↓, *Catalase↑, *SOD↑, *GSH↑, *BDNF↑, *TrkB↑, *NGF↑, *BDNF↑, *NF-kB↓, *AChE↓, *H2S↑, Casp3↑, Apoptosis↑, NF-kB↓, AMPK↑, HO-1↑, MAPK↑, cl‑Casp3↑, cl‑Casp9↑, BAX↑, SOD?, Catalase↓, NRF2↓, NQO1↓, HO-1↓, Bcl-2↓, TumCCA↑, FOXO1↑, TumAuto↑, Akt↓, mTOR↓, P70S6K↓, BMP7/OP1↓, *cardioP↑, *hepatoP↑, *antiCG↑, *AntiThr↑, *Diar↓, *AntiFungal↑, *CYP2D6↓, *PDGFR-BB↓, *PDGFRB↓, *toxicity↓, *Half-Life↑,
7562- HYP,  doxoR,    Hyperoside Inhibits Doxorubicin-Induced Ferroptosis in Cardiomyocytes via the Nrf2/GPX4 Pathway
- in-vivo, Nor, NA
*ROS↓, *Ferroptosis↓, *Apoptosis↓, *cardioP↑, *MDA↓, *SOD↑, *GPx↑, *i-Iron↓, *4-HNE↓, *GSH↑, *Ferritin↑, *ACSL4↓, *NRF2↑, *GPx4↑,
7561- HYP,    Hyperoside Exerts Therapeutic Effects on Parkinson's Disease by Mitigating Oxidative Stress through Activation of Nrf2/HO-1 Pathway
- in-vivo, Park, NA
*motorD↑, *NRF2↑, *HO-1↑, *Bcl-2↑, *BAX↓, *GSH↑, *GPx↑, *SOD↑, *Catalase↑, *MDA↓, *Apoptosis↓,
7560- HYP,    Hyperoside: A Review of Its Structure, Synthesis, Pharmacology, Pharmacokinetics and Toxicity
- Review, Nor, NA - Review, AD, NA
*RenoP↓, Casp3↑, Casp8↑, MDA↑, GSH↓, SOD↓, Catalase↓, VEGF↓, Bcl-2↓, TumCG↓, p‑Akt↓, PI3K↓, TumCCA↑, TumCP↓, BMP7/OP1↓, *ZO-1↑, *BBB↝, *p‑Akt↑, *GSK‐3β↑, *SOD↑, *Catalase↑, *GSH↑, *SIRT1↑, *NF-kB↓, *IL1β↓, *IL6↓, *IL8↓, *TNF-α↓, *ROS↓, *MDA↓, *BAX↓, *Casp3↓, *Bcl-2↑, *BDNF↑, *TrkB↑, *NGF↑, *Apoptosis↓, *cardioP↑, *AST↓, *hepatoP↑, *AST↓, *ALAT↓, *MDA↓, *BACH1↓, *neuroP↑, *Stroke↓, *ICAM-1↓, *VCAM-1↓, *TLR4↓, *COX2/PTGS2↓, *RenoP↑, *NLRP3↓, *Casp1↓, *ASC↓, *BioAv↓, *BioAv↑, *toxicity↓,
7803- IBC,    Isobavachalcone induces hepatotoxicity in zebrafish embryos and HepG2 cells via the System Xc--GSH-GPX4 signaling pathway in ferroptosis response
- in-vivo, Nor, NA - in-vitro, NA, HepG2
*hepatoP↓, *ALAT↑, *AST↑, *ROS↑, *MDA↑, *Catalase↓, *GSH↓, *GPx↓, *i-Iron↑,
7766- ISL,    Isoliquiritigenin alleviates myocardial ischemia-reperfusion injury by regulating the Nrf2/HO-1/SLC7a11/GPX4 axis in mice
- in-vivo, Stroke, NA
*ROS↓, *MDA↓, *LDH↑, *SOD↑, *Catalase↑, *NRF2↑, *i-Iron↓, *GPx4↑, *xCT/SLC7A11↑, *lipid-P↓, *Ferroptosis↓, *HO-1↑, *ACSL4↓, *mtDam↓, *Stroke↓,
7765- ISL,    Isoliquiritigenin as a modulator of the Nrf2 signaling pathway: potential therapeutic implications
- Review, Var, NA
*antiOx↑, *AntiCan↑, *AntiTum↑, *AntiDiabetic↑, *cardioP↑, *RenoP↑, *NRF2↑, *NQO1↝, *HO-1↑, *SOD↑, *toxicity↓, *BioAv↓, *Half-Life↓, *BBB↑, *neuroP↑, *Stroke↓, *GSK‐3β↓, *p‑GSK‐3β↑, *hepatoP↑, *Inflam↓, *ROS↓, *MPO↓, *MDA↓,
7881- isoO,    Effects of Natural Flavonoid Isoorientin on Growth Performance and Gut Microbiota of Mice
- in-vivo, Nor, NA
*Weight↑, *toxicity↓, *GutMicro↑, *SOD↑, *GPx↑, *MDA↓, *Inflam↓,
7878- isoO,  Cisplatin,    Isoorientin Attenuates Cisplatin-Induced Nephrotoxicity Through the Inhibition of Oxidative Stress and Apoptosis via Activating the SIRT1/SIRT6/Nrf-2 Pathway
- in-vivo, Nor, NA
*antiOx↑, *RenoP↑, *chemoP↑, *SIRT1↑, *SIRT6↑, *NRF2↑, *HO-1↑, *NQO1↑, *NOX4↓, *ROS↓, *MPO↓, *MDA↓, *SOD↑, *GSH↑,
7872- isoO,    Isoorientin ameliorates H2O2-induced apoptosis and oxidative stress in chondrocytes by regulating MAPK and PI3K/Akt pathways
- in-vivo, Arthritis, NA
*antiOx↑, *MMP↑, *Apoptosis↓, *MAPK↓, *SOD↑, *HO-1↑, *NQO1↑, *MDA↓, *ROS↓, *NRF2↑, *PI3K↑, *Akt↑,
7871- isoO,  Cisplatin,    Isoorientin reverses lung cancer drug resistance by promoting ferroptosis via the SIRT6/Nrf2/GPX4 signaling pathway
- vitro+vivo, Lung, NA
ChemoSen↑, i-Iron↑, i-MDA↑, *i-ROS↑, GSH↓, Ferroptosis↑, NRF2↓, GPx4↓, SIRT6↓,
7870- isoO,    Anti-oxidative stress and cognitive improvement of a semi-synthetic isoorientin-based GSK-3β inhibitor in rat pheochromocytoma cell PC12 and scopolamine-induced AD model mice via AKT/GSK-3β/Nrf2 pathway
- vitro+vivo, AD, PC12
*GSK‐3β↓, *BAX↓, *Casp3↓, *cl‑Casp3↓, *Bcl-2↑, *MDA↓, *ROS↓, *SOD↑, *GPx↑, *p‑Akt↑, *p‑GSK‐3β↑, *NRF2↑, *p‑CREB↑, *BDNF⇅,
7813- ISQ,    Isoquercitrin Played a Neuroprotective Role in Rats After Cerebral Ischemia/Reperfusion Through Up-Regulating Neuroglobin and Anti-Oxidative Stress
- in-vivo, Stroke, NA
*Apoptosis↓, *ROS↓, *SOD↑, *GSH↑, *Catalase↑, *NRF2↑, *HO-1↑, *MDA↓, *NGB↑, *neuroP↑,
9230- ITCs,  AITC,  BITC,  PEITC,  SFN  Isothiocyanates as Ferroptosis Inducers to Promote Cancer Cell Death
- Review, Var, NA
Ferroptosis↑, Ingr↝, GSH↓, ROS↑, lipid-P↑, MDA↑, GPx4↓, Iron↑, xCT/SLC7A11↓,
8039- IVM,    Ivermectin-Induced Apoptotic Cell Death in Human SH-SY5Y Cells Involves the Activation of Oxidative Stress and Mitochondrial Pathway and Akt/mTOR-Pathway-Mediated Autophagy
- in-vitro, neuroblastoma, SH-SY5Y
*toxicity↑, TumCD↑, ROS↑, mtDam↑, Apoptosis↑, MitoP↑, TumAuto↑, p‑Akt↓, p‑mTOR↓, LC3II↑, Beclin-1/ATG6↑, ATG5↑, PINK1↑, PARK2↑, tumCV↓, MDA↑, SOD↑, Catalase↑, eff↓, MMP↓, BAX↑, cl‑Casp3↑, cl‑Casp9↑, cl‑PARP↑, Cyt‑c↑, Bcl-2↓, proCasp3↓, Bax:Bcl2↑, eff↑, *AntiP↑, *Inflam↓, *AntiDiabetic↑, *AntiViral↑, BBB∅, toxicity↝,
7890- IVT,    Isovitexin protects against cisplatin-induced kidney injury in mice through inhibiting inflammatory and oxidative responses
- in-vivo, Nor, NA
RenoP↑, *BUN↓, *creat↓, *TNF-α↓, *IL1β↓, *IL6↓, *MDA↓, *ROS↓, *NF-kB↓, *NRF2↑, *HO-1↑,
7888- IVT,    Isovitexin Exerts Anti-Inflammatory and Anti-Oxidant Activities on Lipopolysaccharide-Induced Acute Lung Injury by Inhibiting MAPK and NF-κB and Activating HO-1/Nrf2 Pathways
- vitro+vivo, Nor, NA
*Inflam↓, *iNOS↓, *COX2/PTGS2↓, *ROS↓, *Apoptosis↓, *p‑MAPK↓, *NF-kB↓, *NRF2↑, *HO-1↑, *ICAM-1↓, *VCAM-1↓, *MPO↓, *MDA↓, *GSH↑, *SOD↑,
1924- JG,    Juglone triggers apoptosis of non-small cell lung cancer through the reactive oxygen species -mediated PI3K/Akt pathway
- in-vitro, Lung, A549
TumCMig↓, TumCI↓, TumCCA↑, Apoptosis↑, cl‑Casp3↑, BAX↑, Cyt‑c↑, ROS↑, MDA↑, GPx4↓, SOD↓, PI3K↓, Akt↓, eff↓,
1921- JG,    Juglone induces ferroptotic effect on hepatocellular carcinoma and pan-cancer via the FOSL1-HMOX1 axis
- in-vitro, PC, NA - vitro+vivo, PC, NA
TumCG↓, Ferroptosis↑, ROS↑, Iron↑, lipid-P↑, MDA↑, GSH↓, FOSL1↑, HO-1↑,
8105- KAE,    Chemo-preventive and therapeutic effect of the dietary flavonoid kaempferol: A comprehensive review
- Review, Var, NA
Apoptosis↑, tumCV↓, TumCCA↑, PI3K↓, Akt↓, EMT↓, N-cadherin↓, E-cadherin↓, Slug?, Snail?, MMP2↓, MMP9↓, CTSB↓, CTSD↓, Casp3↑, Casp8↑, Casp9↑, TIMP2↓, Akt↓, TumCD↑, i-Ca+2↑, MMP↓, *ROS↓, *SOD↑, *Catalase↑, *GPx↑, *GSTs↑, *AST↓, *ALAT↓, *MDA↓, *CYP2E1↓, *NRF2↑, *AGEs↓, *IL6↓, *TNF-α↓, *NF-kB↓, *Casp3↓, *BAX↓, *antiAll↑, *COX2/PTGS2↓, *PGE2↓, *RUNX2↑, *BMP2↑, *COL1↑, *p62↑, *FASN↓, *DGAT1↓, FOXP3↑, DNAdam↑, ROS↑, Catalase↓, *ROS↓, *MMP↑, *Cyt‑c↓, *AntiDiabetic↑, *Obesity↓, *cardioP↑,

Showing Research Papers: 151 to 200 of 363
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* indicates research on normal cells as opposed to diseased cells
Total Research Paper Matches: 363

Pathway results for Effect on Cancer / Diseased Cells:


NA, unassigned(tgid=0) ⓘ

NA↑, 1,  

Redox & Oxidative Stress(tgid=1) ⓘ

antiOx↓, 1,   antiOx↑, 2,   Catalase↓, 11,   Catalase↑, 12,   Fenton↑, 2,   GCLM↓, 1,   GPx↓, 3,   GPx↑, 7,   GPx4↓, 30,   GPx4↑, 1,   GSH↓, 50,   GSH↑, 10,   GSH/GSSG↓, 2,   GSR↑, 1,   GSTs↓, 1,   GSTs↑, 1,   H2O2↑, 3,   HO-1↓, 6,   HO-1↑, 11,   Iron↑, 25,   Iron↝, 1,   i-Iron↑, 3,   Keap1↑, 3,   lipid-P↓, 3,   lipid-P↑, 23,   MDA?, 1,   MDA↓, 23,   MDA↑, 63,   i-MDA↑, 4,   MPO↓, 2,   NADH↓, 1,   NADPH/NADP+↓, 1,   NFE2L2↑, 1,   NOX↓, 1,   NOX4↓, 1,   NOX4↑, 2,   NQO1↓, 1,   NQO1↑, 3,   NRF2↓, 14,   NRF2↑, 11,   OSI↑, 1,   RNS↑, 1,   ROS?, 1,   ROS↓, 14,   ROS↑, 94,   ROS⇅, 1,   ROS↝, 1,   i-ROS↑, 1,   mt-ROS↑, 1,   SAM-e↝, 1,   SOD?, 1,   SOD↓, 14,   SOD↑, 17,   SOD1↑, 1,   SOD2↓, 2,   SOD2↑, 1,   T-SOD↓, 1,   TAC↓, 2,   TAC↑, 1,   TBARS↓, 1,   TOS↑, 2,   TrxR↓, 2,   uricA↓, 1,   xCT/SLC7A11↓, 8,   xCT/SLC7A11↑, 1,  

Metal & Cofactor Biology(tgid=2) ⓘ

Ferritin↓, 1,   Ferritin↑, 1,   FTH1↓, 6,   FTH1↑, 1,   FTL↑, 1,   IronCh↑, 1,   NCOA4↑, 3,   TfR1/CD71↓, 1,   TfR1/CD71↑, 1,  

Mitochondria & Bioenergetics(tgid=3) ⓘ

CDC25↓, 1,   compI↓, 1,   compII↓, 1,   compIV↓, 1,   EGF↓, 1,   ETC↓, 2,   Insulin↓, 1,   MFN2↑, 1,   mitResp↓, 1,   mtDam↑, 11,   OXPHOS↓, 1,   PGC-1α↑, 1,   PINK1↑, 1,   SDH↓, 1,   SIRT3↓, 1,   SIRT3↑, 1,  

Core Metabolism/Glycolysis(tgid=4) ⓘ

5LO↓, 2,   ACSL4↑, 3,   ALAT↓, 4,   AMPK↓, 1,   AMPK↑, 8,   p‑AMPK↑, 2,   ATP↓, 7,   mt-ATP↓, 1,   citrate↓, 1,   FASN↓, 3,   G6PD↓, 2,   GAPDH↓, 1,   GLS↓, 1,   glucose↓, 1,   GlucoseCon↓, 3,   Glycolysis↓, 9,   GSK‐3β↓, 1,   GSK‐3β↑, 3,   p‑GSK‐3β↓, 2,   HK2↓, 6,   lactateProd↓, 4,   lactateProd↑, 1,   LDHA↓, 3,   NAD↝, 1,   NADPH↑, 1,   PDK1 / PDPK1↓, 2,   PDK3↑, 1,   PFKP↓, 1,   PKM2↓, 2,   PKM2↑, 1,   Pyruv↓, 1,   SCD1↓, 2,   SIRT1↓, 1,   SIRT1↑, 1,   SREBP1/SREBF1↓, 1,   SREBP2↓, 1,   TCA↓, 1,   Warburg↓, 1,  

Cell Death(tgid=5) ⓘ

AIF↑, 2,   APAF1↑, 2,   Apoptosis↓, 3,   Apoptosis↑, 56,   mt-Apoptosis↑, 1,   BAD↑, 1,   Bak↓, 1,   Bak↑, 2,   BAX↓, 1,   BAX↑, 34,   Bax:Bcl2↑, 10,   Bcl-2↓, 36,   Bcl-xL↓, 3,   BID↑, 3,   BIM↑, 1,   Casp↑, 5,   cl‑Casp↑, 1,   Casp12↑, 1,   Casp3↓, 2,   Casp3↑, 46,   cl‑Casp3↑, 6,   cl‑Casp3⇅, 1,   proCasp3↓, 1,   Casp7↑, 7,   Casp8↑, 14,   Casp9↑, 25,   cl‑Casp9↑, 2,   CellShr↑, 1,   cFLIP↓, 1,   Cyt‑c↓, 1,   Cyt‑c↑, 22,   mt-Cyt‑c↓, 1,   DR5↓, 1,   DR5↑, 5,   Endon↑, 1,   FADD↑, 3,   Fas↑, 5,   FasL↑, 1,   Ferroptosis↓, 1,   Ferroptosis↑, 35,   GranB/GZMB↝, 1,   IAP1↓, 1,   IAP2/BIRC3↓, 1,   iNOS↓, 4,   Mcl-1↓, 1,   MDM2↓, 2,   MOMP↑, 2,   necrosis↑, 2,   p38↑, 5,   Perforin↝, 1,   pS2/TFF1↓, 1,   PUMA↑, 1,   Pyro↑, 2,   survivin↓, 6,   TNFR 1↑, 1,   TRAIL↑, 1,   TumCD↑, 6,   XIAP↓, 6,  

Kinase & Signal Transduction(tgid=6) ⓘ

Akt↓, 37,   Akt↑, 4,   p‑Akt↓, 6,   AMPKα↑, 1,   BRAF↑, 1,   BRAF↝, 1,   CaMKII ↓, 1,   cMET↓, 2,   cSrc↓, 1,   EGFR↓, 5,   EGFR↑, 1,   ERK↓, 9,   ERK↑, 3,   p‑ERK↓, 1,   ERK5↓, 1,   FGFR1↓, 1,   HER2/EBBR2↓, 3,   p‑HER2/EBBR2↓, 1,   IGF-1R↓, 2,   IKKα↓, 1,   JAK↓, 1,   JAK1↓, 1,   JAK2↓, 5,   JNK↓, 1,   JNK↑, 4,   p‑JNK↑, 1,   LIMK1↓, 1,   MAPK↓, 10,   MAPK↑, 4,   MAPK↝, 2,   p‑MEK↓, 1,   mTOR↓, 23,   mTOR↑, 1,   mTOR↝, 1,   p‑mTOR↓, 4,   P70S6K↓, 1,   PI3K↓, 31,   PI3K↑, 1,   PI3K/Akt↝, 1,   PKCδ↓, 3,   PTEN↓, 1,   PTEN↑, 3,   PTEN↝, 1,   Raf↓, 2,   RAS↓, 1,   p‑S6K↓, 2,   Sp1/3/4↓, 4,   STAT↓, 2,   STAT3↓, 22,   p‑STAT3↓, 3,   TSC2↑, 1,   p‑TSC2↑, 1,  

Transcription & Epigenetics(tgid=7) ⓘ

ATF4↑, 5,   ATFs↑, 1,   cJun↓, 1,   cMyc↓, 10,   DLEU1↓, 1,   DNMT1↓, 3,   DNMT1↑, 1,   DNMTs↓, 1,   EZH2↓, 3,   FOXO1↓, 1,   FOXO1↑, 1,   FOXO3↓, 2,   FOXO3↑, 2,   p‑FOXO3↓, 1,   FOXO4↓, 1,   FOXO4↑, 1,   HDAC↓, 2,   HDAC1↓, 2,   HDAC2↓, 2,   HDAC3↓, 2,   miR-124-3p↓, 1,   miR-21↓, 1,   miR-21↑, 1,   miR-27a-3p↓, 1,   miR-34a↓, 1,   MYCN↓, 1,   OCT4↓, 4,   other↓, 1,   other↑, 2,   other↝, 2,   PAX2↓, 1,   PhotoS↑, 1,   SOX2↓, 3,   SOX4↓, 2,   SOX9?, 1,   tumCV?, 1,   tumCV↓, 15,   USF1↑, 1,   ZBTB10↑, 1,  

Protein Folding & ER Stress(tgid=8) ⓘ

ATF6↑, 1,   CHOP/DDIT3↑, 6,   eIF2α↑, 2,   p‑eIF2α↑, 1,   ER Stress↑, 11,   GRP78/BiP↑, 2,   HSP27↓, 1,   HSP70/HSPA5↓, 2,   HSP70/HSPA5↑, 2,   HSP90↓, 1,   PERK↑, 1,   UPR↑, 3,  

Autophagy & Lysosomes(tgid=9) ⓘ

ATG5↑, 5,   ATG7↑, 1,   Beclin-1/ATG6↓, 1,   Beclin-1/ATG6↑, 10,   p‑Beclin-1/ATG6↑, 1,   CTSB↓, 1,   CTSD↓, 1,   LC3‑Ⅱ/LC3‑Ⅰ↑, 2,   LC3A↑, 1,   LC3B↑, 1,   LC3B-II↑, 1,   LC3I↑, 1,   LC3II↓, 1,   LC3II↑, 2,   MitoP↑, 1,   p62↓, 1,   p62↑, 1,   PARK2↑, 1,   SESN2↑, 1,   TumAuto↑, 12,  

DNA Damage & Repair(tgid=10) ⓘ

DNAdam↑, 18,   p16↑, 1,   P53↓, 1,   P53↑, 29,   p‑P53↑, 2,   PARP↓, 1,   PARP↑, 6,   cl‑PARP↑, 7,   cl‑PARP1↑, 1,   PCNA↓, 8,   SIRT6↓, 1,   TOP1↓, 1,   TOP2↓, 1,   TOP2↑, 1,   TP53↑, 1,  

Cell Cycle & Senescence(tgid=11) ⓘ

CDK1↓, 4,   CDK1↑, 1,   CDK2↓, 9,   CDK2↑, 2,   CDK4↓, 11,   CDK6↓, 3,   CDK6↑, 1,   CHK1↓, 1,   ChrCon↑, 1,   Cyc↓, 1,   cycA1/CCNA1↓, 2,   CycB/CCNB1↓, 6,   cycD1/CCND1↓, 16,   cycE/CCNE↓, 1,   Ki-67↓, 10,   mitA↑, 1,   P21↓, 1,   P21↑, 16,   p27/CDKN1B↑, 3,   pRB↓, 1,   p‑pRB↓, 1,   RB1↓, 1,   TumCCA↑, 51,  

Proliferation, Differentiation & Cell State(tgid=12) ⓘ

p‑4E-BP1↓, 1,   ALDH↓, 1,   BMP7/OP1↓, 2,   CD133↑, 1,   cFos↓, 2,   CSCs↓, 7,   EIF4E↓, 1,   FGF↓, 2,   FOSL1↑, 1,   GDF15↓, 1,   Gli↓, 1,   HH↓, 2,   IGF-1↓, 3,   IGFBP3↑, 1,   Ki-67↓, 10,   Nanog↓, 4,   NOTCH↓, 2,   NOTCH↑, 1,   NOTCH1↓, 1,   NOTCH1↑, 1,   Shh↓, 1,   STAT1↓, 1,   TumCG↓, 21,   TumCP↓, 42,   Wnt↓, 8,  

Migration(tgid=13) ⓘ

AP-1↓, 3,   AXL↓, 1,   BACH1↓, 1,   BACH1↑, 1,   Ca+2↓, 2,   Ca+2↑, 4,   i-Ca+2↑, 1,   COL1↓, 1,   E-cadherin↓, 3,   E-cadherin↑, 6,   EMT↓, 19,   EMT↝, 1,   F-actin↓, 1,   FAK↓, 1,   p‑FAK↓, 2,   Fibronectin↓, 1,   LAMs↓, 2,   LRP1↑, 1,   MALAT1↓, 1,   MMP1↓, 1,   MMP2↓, 16,   MMP2↑, 1,   MMP3↓, 1,   MMP7↓, 1,   MMP9↓, 23,   MMP9↑, 2,   MMPs↓, 4,   N-cadherin↓, 6,   NeuroT↓, 1,   PCBP1↓, 1,   PDGF↓, 1,   Rho↓, 1,   ROCK1↓, 1,   Slug?, 1,   Slug↓, 2,   SMAD2↓, 1,   SMAD3↓, 1,   Snail?, 1,   Snail↓, 3,   TET1↑, 1,   TGF-β↓, 3,   TGF-β1↓, 1,   THBS1↓, 1,   TIMP2↓, 2,   TIMP2↑, 1,   TSP-1↑, 1,   TumCI↓, 20,   TumCMig↓, 20,   TumMeta↓, 10,   TumMeta↑, 1,   Twist↓, 3,   uPA↓, 3,   uPAR↓, 1,   Vim↓, 7,   Zeb1↓, 2,   α-SMA↓, 1,   β-catenin/ZEB1↓, 10,  

Angiogenesis & Vasculature(tgid=14) ⓘ

angioG↓, 17,   EGR1↓, 1,   Hif1a↓, 16,   Hypoxia↓, 1,   NO↓, 2,   NO↑, 3,   REL↑, 1,   VCAM-1↓, 1,   VEGF↓, 25,   VEGF↑, 1,   VEGFR1↓, 1,   VEGFR2/KDR/Flk1↓, 4,  

Barriers & Transport(tgid=15) ⓘ

BBB↑, 3,   BBB∅, 1,   GLUT1↓, 4,   MMP↓, 24,   MPT↑, 1,   SLC12A5↓, 1,   TRPM7↓, 1,  

Immune & Inflammatory Signaling(tgid=16) ⓘ

CD44↓, 3,   CD47↓, 1,   CD8+↑, 3,   COX2/PTGS2↓, 17,   COX2/PTGS2↑, 2,   CXCc↓, 1,   CXCL12↓, 1,   CXCR2↓, 1,   CXCR4↓, 3,   DR4↑, 3,   FOXP3↑, 1,   HMGB1↓, 2,   ICAM-1↓, 3,   IFN-γ↓, 1,   IL1↓, 2,   IL1↑, 1,   IL10↓, 1,   IL10↑, 2,   IL12↓, 1,   IL1β↓, 4,   IL1β↑, 1,   IL2↓, 2,   IL2↑, 1,   IL4↓, 1,   IL4↑, 1,   IL6↓, 13,   IL8↓, 3,   Imm↑, 5,   Imm↝, 1,   Inflam↓, 5,   pol-M1↑, 2,   M2 MC↓, 1,   MCP1/CCL2↓, 3,   MCT1↓, 1,   NF-kB?, 1,   NF-kB↓, 25,   NF-kB↑, 1,   NK cell↑, 2,   NLRP3↓, 1,   NLRP3↑, 1,   p65↓, 1,   PD-1↓, 1,   PD-L1↓, 4,   PGE2↓, 4,   PSA↓, 1,   PSA∅, 1,   RAGE↓, 1,   Th1 response↑, 1,   Th17↑, 1,   TLR4↓, 3,   TNF-α↓, 10,   TNF-α↑, 3,   TRADD↑, 1,  

Synaptic & Neurotransmission(tgid=18) ⓘ

AChE↓, 1,  

Protein Aggregation(tgid=19) ⓘ

BACE/β-secretase↓, 1,   XO↓, 1,  

Hormonal & Nuclear Receptors(tgid=20) ⓘ

AhR↓, 1,   AR↓, 4,   BNP↓, 1,   ER-α36↓, 1,   GR↑, 1,   PPARγ↓, 1,   PPARγ↑, 3,   PPARγ↝, 1,  

Drug Metabolism & Resistance(tgid=21) ⓘ

ABCG2↓, 1,   BioAv↓, 6,   BioAv↑, 8,   BioAv↝, 2,   BioEnh↑, 2,   chemoR↓, 1,   ChemoSen↑, 40,   CompStab↓, 1,   CompStab↝, 1,   Dose↑, 1,   Dose↝, 17,   eff↓, 13,   eff↑, 12,   eff↝, 1,   eff∅, 1,   GSTA1↓, 1,   GSTM1↑, 1,   Half-Life↓, 1,   Half-Life↝, 2,   MDR1↓, 2,   MRP1/ABCC1↓, 2,   P-gp/ABCB1↓, 4,   P-gp/ABCB1⇅, 1,   RadioS↑, 10,   selectivity↑, 22,   Synergy?, 1,   Synergy↑, 24,  

Clinical Biomarkers(tgid=22) ⓘ

AFP?, 1,   AFP↓, 4,   ALAT↓, 4,   AR↓, 4,   AST↓, 2,   BMD↑, 1,   BRAF↑, 1,   BRAF↝, 1,   BUN↓, 1,   CA19-9↓, 1,   CEA↓, 2,   creat↓, 2,   CRP↓, 2,   EGFR↓, 5,   EGFR↑, 1,   EZH2↓, 3,   Ferritin↓, 1,   Ferritin↑, 1,   HER2/EBBR2↓, 3,   p‑HER2/EBBR2↓, 1,   IL6↓, 13,   LDH↓, 6,   LDH↑, 1,   NOS2↑, 1,   PD-L1↓, 4,   PSA↓, 1,   PSA∅, 1,   RAGE↓, 1,   TP53↑, 1,   Urea↓, 1,  

Functional Outcomes(tgid=23) ⓘ

AntiCan↑, 18,   antiCG↓, 1,   antiNeop↑, 1,   AntiTum↑, 5,   cachexia↓, 1,   cardioP↑, 7,   chemoP↑, 13,   chemoPv↑, 4,   ChemoSideEff↓, 1,   cognitive↑, 1,   hepatoP↑, 8,   memory↑, 1,   neuroP↑, 1,   NP/CIPN↓, 2,   OS↓, 1,   OS↑, 5,   Pain↓, 1,   PFS↑, 1,   QoL↑, 3,   radioP↑, 8,   RenoP↑, 8,   Risk↓, 3,   toxicity↓, 1,   toxicity↑, 1,   toxicity↝, 2,   TumVol↓, 9,   TumW↓, 6,   Weight↑, 2,  

Infection & Microbiome(tgid=24) ⓘ

AntiP↑, 1,   Bacteria↓, 1,   GutMicro↑, 1,  

Ingredients & Constituents(tgid=25) ⓘ

Ingr↝, 6,  
Total Targets: 602

Pathway results for Effect on Normal Cells:


Redox & Oxidative Stress(tgid=1) ⓘ

4-HNE↓, 2,   antiOx?, 2,   antiOx↓, 6,   antiOx↑, 113,   ARE↑, 2,   Bil↑, 2,   Catalase↓, 5,   Catalase↑, 108,   Catalase↝, 1,   Copper↓, 1,   Fenton↓, 3,   GCLC↑, 3,   GCLM↑, 3,   GPx↓, 5,   GPx↑, 81,   GPx∅, 1,   GPx1↑, 1,   GPx4↓, 1,   GPx4↑, 6,   GPx4∅, 1,   GSH↓, 6,   GSH↑, 136,   GSH⇅, 1,   GSH∅, 2,   GSH/GSSG↑, 2,   GSR↓, 3,   GSR↑, 9,   GSSG↓, 6,   GSTs↓, 2,   GSTs↑, 13,   H2O2↓, 9,   H2O2↑, 1,   HDL↓, 1,   HDL↑, 5,   HDL∅, 1,   HNE↓, 1,   HO-1?, 1,   HO-1↓, 5,   HO-1↑, 79,   HO-1⇅, 1,   HO-1∅, 1,   Iron↓, 4,   Iron↝, 1,   i-Iron↓, 3,   i-Iron↑, 1,   Keap1↓, 7,   Keap1↑, 1,   Keap1↝, 1,   lipid-P↓, 61,   lipid-P↑, 1,   mt-lipid-P↓, 1,   MDA?, 1,   MDA↓, 269,   MDA↑, 12,   MDA∅, 1,   MPO↓, 17,   NADH↓, 1,   NOX↓, 2,   NOX4↓, 3,   NQO1↑, 21,   NQO1↝, 1,   Nrf1↑, 1,   NRF2↓, 5,   NRF2↑, 119,   NRF2∅, 1,   p‑NRF2↑, 1,   ONOO↓, 1,   Prx↑, 3,   RNS↓, 3,   ROMO1↑, 1,   ROS?, 2,   ROS↓, 217,   ROS↑, 7,   ROS⇅, 3,   i-ROS↑, 1,   mt-ROS?, 1,   mt-ROS↓, 2,   selenoP↑, 1,   SOD?, 2,   SOD↓, 9,   SOD↑, 183,   SOD↝, 1,   mt-SOD↑, 1,   SOD1↑, 4,   SOD2↑, 2,   TAC↑, 24,   TBARS↓, 5,   Thiols↑, 2,   TOS↓, 2,   Trx↑, 2,   Trx1↑, 2,   TrxR↑, 1,   uricA↓, 3,   VitC↑, 3,   VitE↓, 1,   VitE↑, 1,   xCT/SLC7A11↓, 1,   xCT/SLC7A11↑, 3,  

Metal & Cofactor Biology(tgid=2) ⓘ

Ferritin↑, 1,   FTH1↓, 1,   FTH1↑, 1,   FTL↓, 1,   IronCh↓, 1,   IronCh↑, 7,   Mets↝, 1,   TfR1/CD71↓, 2,  

Mitochondria & Bioenergetics(tgid=3) ⓘ

compII↑, 1,   compIII↑, 1,   Insulin↓, 1,   Insulin↑, 2,   mtDam↓, 7,   NGB↑, 1,   OCR↑, 1,   PGC-1α↑, 2,   PGC-1α↝, 1,   SIRT3↑, 1,   TFAM↑, 2,  

Core Metabolism/Glycolysis(tgid=4) ⓘ

12LOX↓, 1,   15-LOX/ALOX15↓, 1,   5LO↓, 2,   ACC↓, 1,   ACSL4↓, 2,   ACSL4∅, 1,   adiP↓, 1,   ALAT↓, 38,   ALAT↑, 1,   AMP↓, 1,   AMPK↓, 1,   AMPK↑, 13,   ATP↓, 1,   ATP↑, 8,   Buty↑, 1,   cAMP↑, 2,   CRM↑, 2,   DGAT1↓, 1,   FASN↓, 4,   glucose↓, 8,   glucose↝, 1,   GlucoseCon↑, 2,   Glycolysis↑, 1,   GSK‐3β↓, 15,   GSK‐3β↑, 2,   p‑GSK‐3β↑, 2,   H2S↑, 3,   HK2↑, 1,   HMG-CoA↓, 2,   LDL↓, 10,   lipidLev↓, 2,   NAD↑, 1,   NADH:NAD↑, 1,   NADPH↓, 4,   NADPH↑, 3,   PFK↓, 1,   PFK↑, 1,   PKM2↓, 2,   PKM2↑, 1,   PLA2↓, 1,   SCFAs↑, 2,   SIRT1↓, 1,   SIRT1↑, 17,   SREBP1/SREBF1↓, 3,   SREBP2↓, 1,  

Cell Death(tgid=5) ⓘ

AIF↓, 3,   APAF1↓, 1,   Apoptosis↓, 30,   Apoptosis∅, 1,   ASC↓, 1,   BAX↓, 22,   BAX↑, 2,   Bax:Bcl2↓, 2,   Bcl-2↓, 3,   Bcl-2↑, 19,   Bcl-xL↑, 1,   Casp↓, 1,   Casp1↓, 3,   Casp12↓, 1,   Casp3↓, 36,   Casp3↑, 2,   cl‑Casp3↓, 5,   proCasp3↓, 1,   Casp8↓, 2,   Casp9↓, 12,   Casp9↑, 1,   Cyt‑c↓, 6,   Cyt‑c∅, 1,   Fas↓, 1,   Ferroptosis↓, 10,   Ferroptosis↑, 1,   GranB/GZMB↓, 1,   iNOS↓, 42,   iNOS↑, 1,   necrosis↓, 2,   p38↓, 6,   p38↑, 1,   p‑p38↓, 2,   TUNEL↓, 1,  

Kinase & Signal Transduction(tgid=6) ⓘ

Akt↓, 4,   Akt↑, 12,   p‑Akt↓, 4,   p‑Akt↑, 2,   CREB↑, 3,   p‑CREB↑, 2,   ERK↓, 6,   ERK↑, 3,   p‑ERK↓, 2,   p‑ERK↑, 1,   HGF/c-Met↑, 1,   IKKα↓, 2,   JAK2↓, 3,   JAK2↑, 3,   p‑JAK2↓, 1,   JNK↓, 12,   JNK↑, 1,   p‑JNK↓, 3,   MAPK?, 1,   MAPK↓, 15,   MAPK↑, 4,   p‑MAPK?, 1,   p‑MAPK↓, 2,   mTOR↓, 3,   mTOR↑, 3,   p‑mTOR↓, 4,   PDGFR-BB↓, 1,   PDGFRB↓, 1,   PI3K↓, 4,   PI3K↑, 13,   p‑PI3K↓, 1,   PKA↑, 1,   PKCδ↑, 1,   PP2A↑, 2,   PTEN↓, 1,   STAT↓, 1,   STAT3?, 1,   STAT3↓, 5,   STAT3↑, 2,   p‑STAT3↓, 1,  

Transcription & Epigenetics(tgid=7) ⓘ

AntiThr↑, 2,   ATF4↓, 2,   ATF4↑, 1,   cJun↓, 1,   p‑cJun↓, 1,   cMyc↓, 1,   FOXO↑, 1,   FOXO1↑, 1,   FOXO3↑, 2,   HDAC↓, 1,   other?, 3,   other↓, 7,   other↑, 14,   other↝, 5,   RUNX2↑, 1,   SOX2↑, 1,   tumCV↓, 1,  

Protein Folding & ER Stress(tgid=8) ⓘ

ATF6↓, 1,   CHOP/DDIT3↓, 7,   CHOP/DDIT3↑, 1,   p‑eIF2α↓, 1,   ER Stress↓, 11,   GRP78/BiP↓, 10,   GRP78/BiP↑, 2,   GRP94↑, 1,   HSP70/HSPA5↓, 1,   HSP70/HSPA5↑, 6,   HSP70/HSPA5↝, 1,   IRE1↓, 3,   PDI↓, 1,   PERK↓, 1,   XBP-1↓, 1,  

Autophagy & Lysosomes(tgid=9) ⓘ

ATG3↓, 1,   ATG5↑, 1,   Beclin-1/ATG6↓, 1,   Beclin-1/ATG6↑, 6,   LC3‑Ⅱ/LC3‑Ⅰ↑, 1,   LC3B↑, 2,   LC3II↑, 4,   MitoP↑, 1,   p62↓, 1,   p62↑, 3,  

DNA Damage & Repair(tgid=10) ⓘ

DNAdam↓, 10,   P53↓, 2,   PARP1↓, 1,   PCNA↓, 1,   SIRT6↑, 1,  

Cell Cycle & Senescence(tgid=11) ⓘ

CDK5↓, 1,   cycD1/CCND1↓, 1,   Ki-67↓, 2,   Ki-67↑, 1,  

Proliferation, Differentiation & Cell State(tgid=12) ⓘ

BMP2↑, 1,   Diff↝, 1,   IGF-1↓, 1,   Ki-67↓, 2,   Ki-67↑, 1,   Nestin↑, 1,   neuroG↑, 3,   NOTCH1↑, 1,   TumCG↓, 1,   TumCP↓, 3,  

Migration(tgid=13) ⓘ

AntiAg↑, 7,   AP-1↓, 1,   BACH1↓, 1,   Ca+2↓, 9,   cal2↓, 1,   COL1↓, 3,   COL1↑, 2,   COL3A1↓, 1,   E-cadherin↑, 1,   EMT↓, 1,   Fibrosis↓, 1,   heparanase↑, 1,   LRP1↑, 2,   MMP13↓, 1,   MMP2↓, 2,   MMP2↑, 1,   MMP9↓, 8,   MMP9↑, 1,   MMPs↓, 1,   MUC1↑, 1,   ROCK1↓, 1,   Sema3A/PlexinA1↑, 1,   p‑SMAD2↓, 1,   SMAD3↓, 1,   p‑SMAD3↑, 1,   p‑T-cadherin↓, 1,   TGF-β↓, 7,   TGF-β↑, 2,   TGF-β1↓, 3,   TGF-β1↑, 2,   TumCI↓, 2,   TumCMig↓, 1,   TumMeta↓, 1,   TXNIP↓, 3,   Vim↓, 2,   α-SMA↓, 7,   α-SMA↑, 1,  

Angiogenesis & Vasculature(tgid=14) ⓘ

angioG↓, 2,   angioG↑, 1,   E-sel↓, 1,   eNOS↓, 1,   Hif1a↓, 5,   LOX1↓, 1,   NO?, 1,   NO↓, 43,   NO↑, 3,   VCAM-1↓, 8,   VEGF↓, 4,   VEGF↑, 2,  

Barriers & Transport(tgid=15) ⓘ

BBB?, 1,   BBB↓, 3,   BBB↑, 17,   BBB↝, 1,   BBB∅, 2,   GastroP↑, 4,   GLUT2↑, 2,   GLUT3↑, 1,   GLUT4↑, 2,   IBI↑, 5,   MMP↓, 1,   MMP↑, 15,   NHE3↑, 1,   TJ↑, 2,   TRPA1↑, 1,   TRPC1↓, 1,   TRPM7↓, 3,   TRPM7⇅, 1,   ZO-1↓, 1,   ZO-1↑, 2,  

Immune & Inflammatory Signaling(tgid=16) ⓘ

BALF-Infl↓, 2,   BALF-Lym↓, 1,   CD25+↑, 1,   CD4+↑, 3,   CD40↓, 1,   CD8+↑, 1,   COX1↓, 3,   COX2/PTGS2↓, 52,   COX2/PTGS2↑, 2,   CXCL15↓, 1,   CXCR4↓, 1,   Eos↓, 1,   FOXP3↑, 1,   HMGB1↓, 4,   ICAM-1↓, 9,   IFN-γ↓, 6,   IFN-γ↑, 2,   IgE↓, 2,   IL1↓, 3,   IL10↓, 7,   IL10↑, 17,   IL12↓, 4,   IL13↓, 2,   IL17↓, 5,   IL18↓, 2,   IL1β↓, 73,   IL1β↑, 1,   IL2↓, 4,   IL22↓, 1,   IL23↓, 2,   IL33↓, 1,   IL4↓, 8,   IL4↑, 5,   IL5↓, 3,   IL5↑, 1,   IL6?, 1,   IL6↓, 72,   IL6↑, 3,   IL8↓, 11,   Imm↑, 10,   INF-γ↓, 3,   Inflam↓, 147,   Inflam↑, 5,   IP-10/CXCL-10↓, 2,   IRF3↓, 1,   LPS↓, 2,   M2 MC↑, 1,   pol-M2 MC↑, 1,   MCP1/CCL2↓, 8,   MIP2↓, 1,   MyD88↓, 4,   NeuroI↓, 7,   Neut↓, 1,   NF-kB↓, 77,   NK cell↑, 1,   NLRP3↓, 18,   p65↓, 4,   PGE2↓, 18,   PGE2↑, 2,   RAGE↓, 3,   RANTES↓, 2,   SOCS-3↓, 1,   Th2↓, 1,   TLR2↓, 3,   TLR4↓, 25,   TNF-α↓, 104,   TNF-α↑, 3,   TRAF1↓, 1,   TRAF6↓, 1,   Treg lymp↝, 1,   TRIF↓, 2,  

Cellular Microenvironment(tgid=17) ⓘ

Astr↓, 1,   GFAP↓, 3,   GGT/CD224↓, 1,   MGlio↓, 1,  

Synaptic & Neurotransmission(tgid=18) ⓘ

5HT↓, 2,   5HT↑, 5,   Ach↑, 6,   AChE↓, 42,   AChE↝, 1,   ADAM10↑, 1,   BChE↓, 7,   BDNF↑, 30,   BDNF⇅, 1,   BDNF∅, 1,   BrainVol↑, 1,   ChAT↑, 8,   ChE↓, 1,   GABA↑, 2,   GDNF↑, 1,   MAOA↓, 4,   MAOB↓, 2,   monoA↑, 1,   NGF↑, 6,   PSD95↑, 5,   RELN↑, 1,   SNAP25↑, 2,   TPH1↓, 1,   TrkB↑, 5,  

Protein Aggregation(tgid=19) ⓘ

AGEs↓, 3,   APOE4↓, 1,   APP↓, 7,   cl‑APP↑, 1,   Aβ↓, 42,   Aβ42↓, 2,   BACE/β-secretase↓, 19,   PSEN1/PS1↓, 1,   PSEN1/PS1↑, 1,   tau↓, 11,   p‑tau↓, 10,   XO↓, 1,  

Hormonal & Nuclear Receptors(tgid=20) ⓘ

AHR↓, 1,   AKR1C3/17β-HSD5/PGF Synthase↑, 1,   BNP↓, 1,   ER(estro)↓, 1,   ER(estro)↑, 1,   FGF21↑, 1,   GLP-1R↑, 1,   GR↑, 2,   PPARα↑, 2,   PPARα↝, 1,   PPARγ↓, 1,   PPARγ↑, 4,  

Drug Metabolism & Resistance(tgid=21) ⓘ

AKR1B1/ALR2↑, 1,   AKR1B10↝, 1,   BioAv↓, 25,   BioAv↑, 38,   BioAv⇅, 1,   BioAv↝, 12,   BioEnh↑, 1,   ChemoSen↑, 1,   CompStab↝, 1,   CYP2D6↓, 1,   CYP2E1↓, 3,   Dose?, 5,   Dose↓, 1,   Dose↑, 5,   Dose↝, 37,   eff↓, 4,   eff↑, 29,   eff↝, 3,   GSTA1↑, 2,   Half-Life↓, 3,   Half-Life↑, 2,   Half-Life↝, 9,   P-gp/ABCB1↓, 1,   P450↑, 1,   P450↝, 1,   selectivity↑, 1,   Synergy↑, 14,  

Clinical Biomarkers(tgid=22) ⓘ

ALAT↓, 38,   ALAT↑, 1,   ALB↑, 1,   ALP↓, 6,   AST↓, 39,   AST↑, 1,   BG↓, 1,   Bil↑, 2,   BloodF↑, 1,   BMD↑, 3,   BP↓, 6,   BP↝, 1,   BP∅, 1,   BUN?, 1,   BUN↓, 6,   CEA↓, 2,   CK/CK-MB↓, 1,   creat↓, 13,   CRP↓, 13,   Ferritin↑, 1,   hs-CRP↓, 1,   IL6?, 1,   IL6↓, 72,   IL6↑, 3,   LDH↓, 14,   LDH↑, 2,   LDH∅, 1,   NOS2↓, 3,   RAGE↓, 3,   SpO2↑, 1,   TC↓, 2,   TG/TAG↓, 3,   Urea↓, 3,  

Functional Outcomes(tgid=23) ⓘ

Airway↓, 3,   AirwayM↓, 1,   AntiAge↑, 3,   antiAll?, 1,   antiAll↑, 18,   AntiArt↑, 5,   AntiCan↑, 14,   antiCG↑, 1,   AntiDiabetic↑, 23,   antiPs↑, 3,   AntiTum↑, 1,   ANXi↓, 1,   BOLD↑, 1,   cardioP?, 1,   cardioP↑, 40,   CardioT↓, 1,   chemoP↑, 13,   chemoPv↑, 1,   cognitive↓, 1,   cognitive↑, 56,   cognitive∅, 1,   diuretic↑, 1,   hepatoP↓, 3,   hepatoP↑, 63,   Learn↑, 10,   memory↑, 63,   Mood↑, 4,   motorD↑, 6,   Mucositis↓, 1,   neuroP↑, 109,   NP/CIPN↓, 1,   Obesity↓, 10,   OS↑, 4,   Pain↓, 5,   QoL↑, 2,   radioP↑, 7,   RenoP↓, 1,   RenoP↑, 28,   Risk↓, 5,   Sleep↑, 3,   Strength↑, 1,   Stress↓, 1,   Stroke↓, 13,   toxicity↓, 27,   toxicity↑, 2,   toxicity↝, 7,   toxicity∅, 5,   Weight↓, 1,   Weight↑, 3,   Weight∅, 1,   Wound Healing↑, 8,  

Infection & Microbiome(tgid=24) ⓘ

AntiBio↑, 8,   AntiFungal↑, 4,   AntiP↑, 1,   AntiViral↑, 6,   Bacteria↓, 11,   Diar↓, 3,   GutMicro↑, 28,   Inf↓, 1,   Sepsis↓, 9,  

Ingredients & Constituents(tgid=25) ⓘ

Ingr?, 3,   Ingr↝, 4,  
Total Targets: 611

Scientific Paper Hit Count for: MDA, Serum malondialdehyde
17 Curcumin
14 Thymoquinone
12 Hydrogen Gas
11 Silver-NanoParticles
11 Boron
11 Lycopene
11 Quercetin
10 Silymarin (Milk Thistle) silibinin
9 Luteolin
8 Magnetic Fields
7 Propolis -bee glue
6 doxorubicin
6 Betulinic acid
6 Carvacrol
6 Chlorogenic acid
6 Ferulic acid
5 Cisplatin
5 Baicalein
5 Crocetin
5 isoorientin
5 Sulforaphane (mainly Broccoli)
5 Kaempferol
5 L-Theanine
5 Matrine
5 Moringa oleifera
5 Morin
5 Shikonin
4 Resveratrol
4 Alpha-Lipoic-Acid
4 Astaxanthin
4 Berberine
4 Vitamin C (Ascorbic Acid)
4 Chrysin
4 Hyperoside
4 Rosmarinic acid
4 Rutin
3 Allicin (mainly Garlic)
3 Apigenin (mainly Parsley)
3 Melatonin
3 Radiotherapy/Radiation
3 Benzyl isothiocyanate
3 Phenethyl isothiocyanate
3 α-Bisabolol / Chamomile oil
3 Centella asiatica / Gotu kola → asiaticoside
3 Chemotherapy
3 Spirulina(Arthrospira/Limnospira)
3 EGCG (Epigallocatechin Gallate)
3 Selenium NanoParticles
3 Selenite (Sodium)
3 Vitexin
2 1,8-Cineole
2 Phyllanthus emblica/Emblica officinalis/Amla / Indian Gooseberry
2 Andrographis
2 Artemisinin
2 Ashwagandha(Withaferin A)
2 Ascorbyl Palmitate
2 Allyl isothiocyanate
2 borneol
2 Selenium
2 Caffeic Acid Phenethyl Ester (CAPE)
2 Thymol-Thymus vulgaris
2 Carvone
2 Copper and Cu NanoParticles
2 Chlorella (Chlorella vulgaris)
2 Dandelion Root
2 Emodin
2 Sesame seeds and Oil
2 Gallic acid
2 Graviola
2 HydroxyCitric Acid
2 Isoliquiritigenin
2 Isovitexin
2 Juglone
2 Licochalcone A
2 Licorice
2 Linalool
2 Magnolol
2 Lemon Balm/Melissa officinalis
2 Nimbolide
2 Marjoram (Origanum majorana)
2 Piperlongumine
2 Pterostilbene
1 3-bromopyruvate
1 cetuximab
1 5-Hydroxytryptophan
1 Anthocyanins
1 Paclitaxel/Taxol
1 Baicalin
1 Biochanin A
1 Bromelain
1 Boswellia (frankincense)
1 Caffeic acid
1 Carnosic acid
1 NTP, Non-Thermal Plasma,Cold Atmospheric Plasma
1 Cynanbungeigenin C (CBC) and D (CBD)
1 Celastrol
1 chitosan
1 Chlorophyllin
1 Chocolate
1 Cichoric acid / Chicoric acid
1 Cinnamon
1 Citric Acid
1 Coenzyme Q10
1 Carica papaya leaf extract
1 Cynara scolymus/Globe Artichoke/Artichoke Extract
1 Galantamine
1 Diclofenac
1 Docosahexaenoic Acid
1 diet Methionine-Restricted Diet
1 Diindolylmethane
1 D-limonene
1 Ellagic acid
1 Eurycomanone
1 Eugenol
1 Formononetin
1 Flaxseed/Linseed
1 Flaxseed Oil
1 Fucoidan
1 Ginkgo biloba
1 Ginger/6-Shogaol/Gingerol
1 Huperzine A/Huperzia serrata
1 Isobavachalcone
1 isoquercitrin
1 Isothiocyanates
1 Ivermectin
1 Lactoferrin/Talactoferrin
1 SDG/lignans
1 Vitamin E
1 Metformin
1 Magnetic Field Rotating
1 Magnesium
1 Methylsulfonylmethane
1 Mushroom Lion’s Mane, Hericium erinaceus
1 Myricetin
1 Oleuropein
1 HydroxyTyrosol
1 Aromatherapy
1 buckwheat sprouts
1 Orlistat
1 salinomycin
1 Sulfasalazine
1 Anti-oxidants
1 Date Fruit Extract
1 Sesamin
1 Lignans
1 Shankhpushpi
1 Silicic Acid
1 Safflower yellow
1 Taurine
1 5-fluorouracil
1 Urolithin
1 Vitamin D3
Query results interpretion may depend on "conditions" listed in the research papers.
Such Conditions may include : 
  -low or high Dose
  -format for product, such as nano of lipid formations
  -different cell line effects
  -synergies with other products 
  -if effect was for normal or cancerous cells

Filter Conditions: Pro/AntiFlg:%  IllCat:%  CanType:%  Cells:%  prod#:%  Target#:570  State#:%  Dir#:%
  wNotes=0  sortOrder:rid,rpid

 

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