mtDam Cancer Research Results

mtDam, mitochondrial damage: Click to Expand ⟱
Source:
Type:
Mitochondrial damage can lead to a shift from oxidative phosphorylation to glycolysis, a process known as the Warburg effect. This shift can provide cancer cells with a selective advantage, allowing them to grow and proliferate more rapidly.
Mitochondrial Damage can also lead to cell death of cancer cells.
Scientific Papers found: Click to Expand⟱
2547- M-Blu,  SDT,    The effect of dual-frequency ultrasound waves on B16F10 melanoma cells: Sonodynamic therapy using nanoliposomes containing methylene blue
- in-vitro, Melanoma, B16-BL6
tumCV↓, ROS↑, mtDam↑,
8498- MAG,    Induction of apoptosis by magnolol via the mitochondrial pathway and cell cycle arrest in renal carcinoma cells
- in-vitro, Kidney, 786-O - in-vitro, RCC, OS-RC-2 - in-vitro, Nor, HK-2
Apoptosis↑, TumCCA↑, selectivity↑, TumCMig↓, TumCI↓, MPT↑, ROS↓, MMP↓, mtDam↑,
8501- MAG,    Synergistic effects of autophagy/mitophagy inhibitors and magnolol promote apoptosis and antitumor efficacy
- vitro+vivo, neuroblastoma, NA
MMP↓, mtDam↑, ROS↑, PINK1↑, TumCG↓, OS↑, TumAuto↑, MitoP↑,
4524- MAG,    Magnolol facilitates mitochondrial-peroxisome dysfunction and induces oxeiptosis in lung cancer cells following transfer via tunneling nanotubes
- vitro+vivo, Lung, NA
ROS↑, antiOx↓, mtDam↑,
8560- Matr,    Matrine: A Promising Natural Product With Various Pharmacological Activities
- Review, AD, NA - Review, Stroke, NA - Review, Var, NA
*antiAll↑, *Stroke↓, *AntiArt↑, TumCCA↑, VEGF↓, Apoptosis↑, P53↑, P21↑, PCNA↓, EIF4E↓, TumCP↓, TumCMig↓, IAP1↓, ROS↑, EMT↓, PAX2↓, ER Stress↑, HK2↓, Apoptosis↑, STAT3↓, mtDam↑, HMGB1↓, ChemoSen↑, p‑GSK‐3β↓, P-gp/ABCB1↓, MRP1/ABCC1↓, Vim↓, cycD1/CCND1↓, CDK4↓, GSH↓, SOD↓, mt-Cyt‑c↓, BAX↑, MMP9↓, MMP2↓, E-cadherin↓, N-cadherin↓, FOXO1↓, FOXO3↓, FOXO4↓, PI3K↓, ATF4↑, CHOP/DDIT3↑, *Aβ↓, *RAGE↓, *memory↑, *Learn↑, *cognitive↑, *MDA↓, *SOD↑, *GPx↑, *Catalase↑, *antiAll↑, *AHR↓, *SOCS-3↓, *ICAM-1↓, *ROS↓, cachexia↓, *BACE/β-secretase↓, *NF-kB↓, *TNF-α↓, *IL1β↓,
8714- MeJa,    Methyl jasmonate binds to and detaches mitochondria-bound hexokinase
- in-vitro, Colon, CT26
HK2↓, eff↝, mtDam↑, ATP↓, other↝,
7384- MF,    Reactive oxygen species (ROS) production in HepG2 cancer cell line through the application of localized alternating magnetic field
- in-vitro, Liver, HepG2
ROS↑, tumCV↓, mtDam↑, Dose↝, ER Stress↑,
7383- MF,    Magneto mitochondrial dysfunction mediated cancer cell death using intracellular magnetic nano-transducers
- vitro+vivo, Var, NA
mtDam↑, Apoptosis↑, MitoP↑, Dose↝, Dose↝, eff↑, PINK1↑, PARK2↑,
184- MFrot,  MF,    Rotating Magnetic Fields Inhibit Mitochondrial Respiration, Promote Oxidative Stress and Produce Loss of Mitochondrial Integrity in Cancer Cells
- in-vitro, GBM, GBM
ROS↑, mitResp↓, mtDam↑, Dose↝, MMP?, OCR↓, mt-H2O2↑, eff↓, SDH↓, Thiols↓, GSH↓, TumCD↑, Casp3↑, Casp7↑, MPT↑, Cyt‑c↑, selectivity↑, GSH/GSSG↓, ETC↓,
9085- MGF,    The Protective Effect of Mangiferin on Formaldehyde-Induced HT22 Cell Damage and Cognitive Impairment
- vitro+vivo, AD, HT22
*p‑tau↓, *ER Stress↓, *GRP78/BiP↓, *CHOP/DDIT3↓, *GSK‐3β↓, *CaMKII ↓, *Ca+2↓, *ROS↓, *mtDam↓, *Dose↝, *Learn↑, *memory↑, *neuroP↑, *cognitive↑,
9089- MGF,    Mangiferin targeting HSP90α induces DNA damage in cutaneous squamous cell carcinoma via the ROS/MAPK signaling pathway
- in-vitro, SCC, NA
TumCP↓, Apoptosis↑, TumCCA↑, HSP90↓, ROS↑, mtDam↑, eff↓, toxicity↓, MAPK↑,
8660- MLT,    Unraveling the impact of melatonin treatment: Oxidative stress, metabolic responses, and morphological changes in HuH7.5 hepatocellular carcinoma cells
- in-vitro, CCA, HuH28
AntiTum↑, Dose↝, ROS↑, mtDam↑, TumCCA↑, Apoptosis↑,
8689- MLT,    Role of melatonin in Alzheimer's disease: From preclinical studies to novel melatonin-based therapies
- Review, AD, NA
*neuroP↑, *Aβ↓, *ROS↓, *NeuroI↓, *Apoptosis↓, *mtDam↓, *GSK‐3β↓, *p‑tau↓, *GFAP↓, *TNF-α↓, *IL6↓, *BACE/β-secretase↓, *PSEN1/PS1↓, *NF-kB↓, *TFAM↑, *Nrf1↑, *NRF2↑, *PGC-1α↑, *MMP↑, *GSH↑, *lipid-P↓, *ChAT↑, *TBARS↓, *SOD↑, *Ca+2↓, *AChE↓, *H2O2↓, *MDA↓, *TAC↑, *SOD↑, *Catalase↑, *BDNF↑, *Bcl-2↑, *Ach↑, *memory↑, *Learn↑, *GSK‐3β↓, *SNAP25↑, *PSD95↑, *p‑CREB↑, *GFAP↓, *RELN↑, *SIRT1↑, *TFAM↑, *APP↓, *ER Stress↓, *GRP78/BiP↓, *Sleep↑, *cognitive↑, *Synergy↑, *NeuroI↓,
8880- MOR,    Morin, a Natural Flavonoid, Activates the PINK1/Parkin Pathway to Induce Mitophagy, Promote Apoptosis, and Suppress Cancer Stemness in Pancreatic Cancer
- in-vitro, PC, NA
tumCV↓, TumCMig↓, TumCI↓, CSCs↓, N-cadherin↓, Snail↓, Zeb1↓, SOX2↓, Nanog↓, OCT4↓, E-cadherin↑, ALDH↓, mtDam↑, MMP↓, compV↓, mt-ROS↑, PINK1↑, PARK2↑, AMPK↑, LC3A↑, LC3B↑, MFN2↓, MitoP↑, Apoptosis↑, Casp3↑, Casp9↑, Cyt‑c↑,
9301- MushMait,    Evaluating the anticancer activity of black maitake odaira extract-prothera (Grifola frondosa) and its interactions with common chemotherapeutics in in-vitro and in-vivo models of human colorectal cancers
- vitro+vivo, CRC, HCT116 - in-vitro, CRC, HT-29
Ingr↝, Imm↑, TumMeta↓, ChemoSen↑, Apoptosis↑, Apoptosis↑, tumCV↓, TumCMig↓, ROS↑, mtDam↑, selectivity?,
2933- NAD,    Nicotinamide mononucleotide (NMN) as an anti-aging health product – Promises and safety concerns
- Review, Nor, NA - NA, AD, NA - NA, Diabetic, NA - NA, Stroke, NA - NA, LiverDam, NA - NA, Park, NA
*mtDam↓, *BioAv↝, *BioAv↑, *OS↑, *eff↑, *eff↑, *cognitive↑, *DNAdam↓, *SIRT1↑, *cardioP↑, *ROS↓, *Dose↝, *BioAv↑, *hepatoP↑, *eff↑, *BG↓, *creat↓,
5609- NaHCO3,    Alkalization of cellular pH leads to cancer cell death by disrupting autophagy and mitochondrial function
- in-vitro, Var, NA
eff↑, e-pH↑, MMP↓, OXPHOS↝, AMP↑, TumAuto↑, MPT↑, mtDam↑,
4974- Nimb,    Nimbolide Induces ROS-Regulated Apoptosis and Inhibits Cell Migration in Osteosarcoma
- in-vitro, OS, NA
Apoptosis↑, ER Stress↑, mtDam↑, ROS↑, Casp↑, TumCMig↓, TumMeta↓,
2452- PA,    Targeting Pyruvate Kinase M2 and Hexokinase II, Pachymic Acid Impairs Glucose Metabolism and Induces Mitochondrial Apoptosis
- in-vitro, BC, SkBr3
HK2↓, GlucoseCon↓, lactateProd↓, mtDam↑, ATP↓, ROS↑, PKM2↑,
2053- PB,    4-Phenyl butyric acid prevents glucocorticoid-induced osteoblast apoptosis by attenuating endoplasmic reticulum stress
- in-vitro, ostP, 3T3
*ER Stress↓, *mtDam↓, *Apoptosis↓, eff↑,
3251- PBG,    The Antioxidant and Anti-Inflammatory Effects of Flavonoids from Propolis via Nrf2 and NF-κB Pathways
- Review, AD, NA - Review, Diabetic, NA - Review, Var, NA - in-vitro, Nor, H9c2
*antiOx↑, *Inflam↓, *ROS↓, *SOD↑, *Catalase↑, *HO-1↑, *NO↓, *NOS2↓, *NF-kB↓, *NRF2↑, *hepatoP↑, *MDA↓, *mtDam↓, *GSH↑, *p65↓, *TNF-α↓, *IL1β↓, *NRF2↑, *NRF2↓, *ROS⇅, *BioAv↓, *BioAv↑,
1672- PBG,    The Potential Use of Propolis as an Adjunctive Therapy in Breast Cancers
- Review, BC, NA
ChemoSen↓, RadioS↑, Inflam↓, AntiCan↑, Dose∅, mtDam↑, Apoptosis?, OCR↓, ATP↓, ROS↑, ROS↑, LDH↓, TP53↓, Casp3↓, BAX↓, P21↓, ROS↑, eNOS↑, iNOS↑, Synergy↑, hTERT/TERT↓, cycD1/CCND1↓, Synergy↑, Synergy↑, eff↑, eff↑, STAT3↓, TIMP1↓, IL4↓, IL10↓, OS↑, Dose∅, ER Stress↑, ROS↑, NF-kB↓, p65↓, MMP↓, TumAuto↑, LC3II↑, p62↓, TLR4↓, mtDam↑, LDH↓, ROS↑, Glycolysis↓, HK2↓, PFK↓, PKM2↓, LDH↓, IL10↓, HDAC8↓, eff↑, eff↑, P21↑,
1674- PBG,  SDT,  HPT,    Study on the effect of a triple cancer treatment of propolis, thermal cycling-hyperthermia, and low-intensity ultrasound on PANC-1 cells
- in-vitro, PC, PANC1 - in-vitro, Nor, H6c7
tumCV↓, ROS↑, eff↑, Dose∅, selectivity↑, MMP↓, mtDam↑, cl‑PARP↑, p‑ERK↓, p‑JNK↑, p‑p38↑, eff↓, ChemoSen↑,
1660- PBG,    Emerging Adjuvant Therapy for Cancer: Propolis and its Constituents
- Review, Var, NA
MMPs↓, angioG↓, TumMeta↓, TumCCA↑, Apoptosis↑, ChemoSideEff↓, eff∅, HDAC↓, PTEN↑, p‑PTEN↓, p‑Akt↓, Casp3↑, p‑ERK↑, p‑FAK↑, Dose?, Akt↓, GSK‐3β↓, FOXO3↓, ChemoSen↑, IL2↑, IL10↑, NF-kB↓, VEGF↓, mtDam↑, ER Stress↑, AST↓, ALAT↓, ALP↓, COX2/PTGS2↓, eff↑, Bax:Bcl2↑,
1663- PBG,    Propolis and Their Active Constituents for Chronic Diseases
- Review, Var, NA
NF-kB↓, Casp↓, Fas↓, DNAdam↑, Casp3↑, P53↝, MMP↝, ROS↑, mtDam↑, Dose?, angioG↓, TumCP↓, TumCMig↓, BAX↑, selectivity↑, MMP↓, LDH↓, IL6↓, IL1β↓, TNF-α↓,
4945- PEITC,    Phenethyl isothiocyanate (PEITC) promotes G2/M phase arrest via p53 expression and induces apoptosis through caspase- and mitochondria-dependent signaling pathways in human prostate cancer DU 145 cells
- in-vitro, Pca, DU145
AntiCan↑, TumCG↓, Apoptosis↑, tumCV↓, TumCCA↑, DNAdam↑, P53↑, CDC25↓, Casp9↑, Casp8↑, mtDam↑, Cyt‑c↑,
4954- PEITC,    Selective killing of oncogenically transformed cells through a ROS-mediated mechanism by β-phenylethyl isothiocyanate
- vitro+vivo, Ovarian, SKOV3
ROS↑, GSH↓, selectivity↑, mtDam↑, TumCD↑, OS↑, eff↑, *toxicity↓, H2O2↑, NO↑, eff↓, GPx↓, Dose↝, Synergy↑,
4956- PEITC,    Inhibition of cancer growth in vitro and in vivo by a novel ROS-modulating agent with ability to eliminate stem-like cancer cells
- vitro+vivo, Lung, A549
GSH↓, ROS↑, mtDam↑, mitResp↓, MMP↓, CSCs↓, OCT4↓, ABC↓, SOX2↓, CD133↓, CD44↓, ALDH↓, Nanog↓, TumCG↓,
9029- Phyco,    Advances about the study of phycocyanin in the treatment of breast cancer: A review
- Review, BC, NA
*antiOx↓, *Inflam↓, AntiTum↑, Apoptosis↑, ROS↑, mtDam?, TumCCA↑, TumCP↓, Tumccf↓, *toxicity↓, TumCG↓, EMT↓, COX2/PTGS2↓,
9030- Phyco,    Enhancing the gastrointestinal stability of phycocyanin through modified PEGylation: Prospects for oral anticancer treatment
- in-vitro, Oral, NA
BioAv↓, Synergy↑, BioAv↑, tumCV↓, ROS↑, mtDam↑,
1947- PL,    Piperlongumine as a direct TrxR1 inhibitor with suppressive activity against gastric cancer
- in-vitro, GC, SGC-7901 - in-vitro, GC, NA
TrxR1↓, ROS↑, ER Stress↑, mtDam↑, selectivity↑, NO↑, TumCCA↑, mt-ROS↑, Casp9↑, Bcl-2↓, Bcl-xL↓, cl‑PARP↑, eff↓, lipid-P↑,
2006- PLB,    Plumbagin induces apoptosis in human osteosarcoma through ROS generation, endoplasmic reticulum stress and mitochondrial apoptosis pathway
- in-vitro, OS, MG63 - in-vitro, Nor, hFOB1.19
tumCV↓, selectivity↑, mtDam↑, Ca+2↓, ER Stress↑, ROS↑, Casp3↑, Casp9↑, Apoptosis↑, eff↓,
6422- QC,    Quercetin Protects Ethanol-Induced Hepatocyte Pyroptosis via Scavenging Mitochondrial ROS and Promoting PGC-1α-Regulated Mitochondrial Homeostasis in L02 Cells
- in-vitro, Alcohol, L02
*mt-ROS↓, *lipid-P↓, *MMP↑, *mtDam↓, *NLRP3↓, *ASC↓, *cl‑Casp1↓, *IL18↓, *IL1β↓, *GSDMD↓, *Pyro↓, *CYP2E1↓, *MFN1↓, *MFN2↓, *OPA1↓, *DRP1/DNM1L↑,
5781- RES,    Resveratrol improves health and survival of mice on a high-calorie diet
- in-vivo, Nor, NA
*AntiAge↑, *IGF-1↓, *AMPK↑, *CRM↑, *PGC-1α↑, *mtDam↓, *motorD↑, *hepatoP↑, *Dose↝,
5788- RES,    Calorie restriction-like effects of 30 days of Resveratrol (resVida™) supplementation on energy metabolism and metabolic profile in obese humans
- Trial, Nor, NA
*AMPK↑, *SIRT1↑, *PGC-1α↑, *BP↓, *CRM↑, *Dose↝, *mtDam↓, *ALAT↓, *hepatoP↑,
3073- RES,    Resveratrol inhibits NLRP3 inflammasome activation by preserving mitochondrial integrity and augmenting autophagy
- in-vitro, Nor, NA
*NLRP3↓, *mtDam↓, *p38↑,
4909- Sal,    Salinomycin: Anti-tumor activity in a pre-clinical colorectal cancer model
- vitro+vivo, CRC, NA
AntiTum↑, Apoptosis↑, mtDam↑, ROS↑, SOD1↓, ChemoSen↑, CSCs↑, ALDH↓, TumCG↓, TumCP↓, TumCD↑, ATP↓,
1208- SANG,    Sanguinarine induces apoptosis in osteosarcoma by attenuating the binding of STAT3 to the single-stranded DNA-binding protein 1 (SSBP1) promoter region
- in-vitro, OS, NA
SSBP1↑, mtDam↑, Apoptosis↑, JAK↓, STAT3↓, PI3k/Akt/mTOR↓, ROS↑, MMP↓,
1403- SDT,  BBR,    From 2D to 3D In Vitro World: Sonodynamically-Induced Prooxidant Proapoptotic Effects of C60-Berberine Nanocomplex on Cancer Cells
- in-vitro, Cerv, HeLa - in-vitro, Lung, LLC1
eff↑, tumCV↓, ATP↓, ROS↑, Casp3↑, Casp7↑, mtDam↑,
4480- SeNPs,  Chit,    Biogenic synthesized selenium nanoparticles combined chitosan nanoparticles controlled lung cancer growth via ROS generation and mitochondrial damage pathway
- in-vitro, Lung, A549 - in-vitro, Nor, HK-2
selectivity↑, *toxicity↓, ROS↑, mtDam↑, Apoptosis↑, LDH↑,
2410- SIL,    Autophagy activated by silibinin contributes to glioma cell death via induction of oxidative stress-mediated BNIP3-dependent nuclear translocation of AIF
- in-vitro, GBM, U87MG - in-vitro, GBM, U251 - in-vivo, NA, NA
TumAuto↑, ATP↓, Glycolysis↓, H2O2↑, P53↑, GSH↓, xCT/SLC7A11↓, BNIP3↝, MMP↑, mt-ROS↑, mtDam↑, HK2↓, PFKP↓, PKM2↓, TumCG↓,
2198- SK,    Shikonin suppresses proliferation of osteosarcoma cells by inducing ferroptosis through promoting Nrf2 ubiquitination and inhibiting the xCT/GPX4 regulatory axis
- in-vitro, OS, MG63 - in-vitro, OS, 143B
TumCP↓, TumCCA↑, Ferroptosis↑, Iron↑, ROS↑, lipid-P↑, MDA↑, mtDam↑, NRF2↓, xCT/SLC7A11↓, GPx4↓, GSH/GSSG↓, Keap1↑,
9033- SP,    Spirulina and Its Bioactive Compounds as Multi-Target Anticancer Agents: Mechanisms, Immune Modulation, and Translational Potential
- Review, Var, NA
Apoptosis↑, TumCCA↑, angioG↓, VEGF↓, VEGFR1↓, EMT↓, Ingr↝, Imm↑, pol-M1↑, Th1 response↑, Th17↑, chemoP↑, BioAv↓, Synergy?, Ingr↝, Ingr↝, Ingr↝, ROS⇅, ROS↑, mtDam↑, DNAdam↑, SOD↓, Bcl-2↓, Casp3↑, MDA↓, Catalase↑, ROS↓, MOMP↑, Cyt‑c↑, Casp9↑, CellShr↑, ChrCon↑, Dose↝, TNFR 1↑, FADD↑, TRADD↑, Beclin-1/ATG6↑, PI3K↓, Akt↓, mTOR↓, TumAuto↑, TumCMig↓, TumCI↓, Vim↓, Fibronectin↓, COL1↓, MMP2↓, MMP9↓, COX2/PTGS2↓, MCP1/CCL2↓, ICAM-1↓, VCAM-1↓, Snail↓, Slug↓, Zeb1↓, Twist↓, E-cadherin↑, chemoP↑, *hepatoP↑, *lipid-P↓, *Casp3↓, *BAX↓, RenoP↑, *creat↓, *Urea↓, *SOD↑, *Catalase↑, *neuroP↑, *cognitive↑, *ROS↓, *NeuroI↓, *memory↑, *BDNF↑, *CREB↑, *toxicity↓, *toxicity↝, *BioAv↓, *BioAv↓, *Half-Life↝,
5075- SSE,    Sodium selenite inhibits proliferation and metastasis through ROS‐mediated NF‐κB signaling in renal cell carcinoma
- vitro+vivo, RCC, 786-O
TumCP↓, TumCMig↓, Apoptosis↑, ROS↑, NF-kB↓, eff↓, E-cadherin↑, cl‑Casp3↑, VEGF↓, MMP9↓, EMT↓, MMP↓, mtDam↑, BAX↑, Bcl-2↓,
5111- SSE,    Sodium selenite induces apoptosis via ROS-mediated NF-κB signaling and activation of the Bax-caspase-9-caspase-3 axis in 4T1 cells
- in-vitro, BC, 4T1
ROS↑, NF-kB↓, p65↓, mtDam↑, Casp9↑, Casp3↑, Apoptosis↑, eff↓,
5095- SSE,    Extracellular thiol-assisted selenium uptake dependent on the xc− cystine transporter explains the cancer-specific cytotoxicity of selenite
- in-vitro, Lung, H157
toxicity↝, eff↓, other↝, ROS↑, mtDam↑,
5089- SSE,  Se,    Redox-mediated effects of selenium on apoptosis and cell cycle in the LNCaP human prostate cancer cell line
- in-vitro, Pca, LNCaP
ROS↑, mtDam↑, TumCD↑, Apoptosis↑, TumCCA↑, Trx↓, angioG↓, GSH⇅, NADPH↓, GPx↑,
5021- UA,    Anticancer effect of ursolic acid via mitochondria-dependent pathways
- Review, Var, NA
Inflam↓, TNF-α↓, IL6↓, IL17↓, NF-kB↓, COX2/PTGS2↓, *AntiDiabetic↑, *hepatoP↑, ALAT↓, AST↓, TumCP↓, Apoptosis↑, TumCCA↑, TumAuto↑, tumCV↓, TumCMig↓, Glycolysis↓, ATP↓, lactateProd↓, HK2↓, PKA↓, COX2/PTGS2↓, mtDam↑, Casp3↑, Casp8↑, Casp9↑, Akt↓, ROS↑, MMP↓, P53↑,
4835- Uro,    Urolithin A, induces apoptosis and autophagy crosstalk in Oral Squamous Cell Carcinoma via mTOR /AKT/ERK1/2 pathway
- in-vitro, SCC, NA
TumCD↑, ER Stress↑, Akt↓, mtDam↓, p‑mTOR↓, *BioAv↝, ROS↑, TumCCA↑, Apoptosis↑, ERK↓,
7914- VT,    Vitexin induces apoptosis through mitochondrial pathway and PI3K/Akt/mTOR signaling in human non-small cell lung cancer A549 cells
- vitro+vivo, Lung, A549
tumCV↓, selectivity↑, Cyt‑c↑, MMP↓, p‑PI3K↓, p‑Akt↓, p‑mTOR↓, TumCG↓, mtDam↑, LDH↑, Bax:Bcl2↑, cl‑Casp3↑,

Showing Research Papers: 151 to 200 of 201
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* indicates research on normal cells as opposed to diseased cells
Total Research Paper Matches: 201

Pathway results for Effect on Cancer / Diseased Cells:


NA, unassigned(tgid=0) ⓘ

NA↓, 1,   NA↑, 1,  

Redox & Oxidative Stress(tgid=1) ⓘ

antiOx↓, 1,   antiOx↑, 1,   ARE↓, 1,   Catalase↓, 2,   Catalase↑, 2,   Fenton↑, 3,   GPx↓, 4,   GPx↑, 1,   GPx4↓, 5,   GSH↓, 17,   GSH↑, 1,   GSH⇅, 1,   GSH/GSSG↓, 3,   GSSG↑, 1,   H2O2↑, 4,   i-H2O2↑, 1,   mt-H2O2↑, 1,   HO-1↑, 4,   Iron↑, 7,   i-Iron↑, 1,   Keap1↓, 1,   Keap1↑, 1,   lipid-P↑, 11,   MDA↓, 1,   MDA↑, 4,   i-MDA↑, 1,   NADPH/NADP+↓, 1,   NQO1↑, 1,   NRF2↓, 3,   NRF2↑, 2,   Prx↓, 1,   PrxII↓, 1,   ROS?, 1,   ROS↓, 6,   ROS↑, 128,   ROS⇅, 1,   ROS∅, 1,   mt-ROS↑, 7,   SOD↓, 5,   SOD↑, 1,   mt-SOD↑, 1,   SOD1↓, 1,   SOD2↓, 1,   SOD2↑, 1,   Thiols↓, 1,   Trx↓, 1,   TrxR1↓, 2,   xCT/SLC7A11↓, 3,  

Metal & Cofactor Biology(tgid=2) ⓘ

FTH1↓, 1,   IronCh↑, 1,   NCOA4↑, 1,   SFXN2↓, 1,  

Mitochondria & Bioenergetics(tgid=3) ⓘ

CDC2↓, 1,   CDC25↓, 6,   compI↓, 4,   compII↓, 2,   compIV↓, 1,   compV↓, 1,   ETC↓, 3,   HSP60/HSPD1↓, 1,   HTRA2/Omi/PARK13↑, 1,   MFN2↓, 1,   mitResp↓, 4,   mtDam?, 1,   mtDam↓, 3,   mtDam↑, 160,   OCR↓, 5,   OXPHOS↓, 1,   OXPHOS↝, 1,   mt-OXPHOS↓, 1,   PINK1↑, 4,   SDH↓, 2,   SSBP1↑, 1,  

Core Metabolism/Glycolysis(tgid=4) ⓘ

ACLY↓, 1,   ALAT↓, 3,   AMP↑, 1,   AMPK↑, 7,   ATP↓, 23,   DHODH↓, 2,   GAPDH↓, 1,   glucose↓, 1,   GlucoseCon↓, 3,   Glycolysis↓, 13,   GSK‐3β↓, 1,   p‑GSK‐3β↓, 2,   HK2↓, 12,   lactateProd↓, 5,   LDHA↓, 2,   LDL↓, 1,   lipoGen↓, 1,   NADPH↓, 2,   PDK1 / PDPK1↓, 1,   PFK↓, 1,   PFKP↓, 2,   PKM2↓, 3,   PKM2↑, 2,   Pyruv↓, 1,   SIRT1↓, 1,   Warburg↓, 1,  

Cell Death(tgid=5) ⓘ

AIF↑, 3,   APAF1↑, 1,   Apoptosis?, 2,   Apoptosis↓, 2,   Apoptosis↑, 86,   mt-Apoptosis↑, 2,   BAD↑, 3,   Bak↑, 2,   BAX↓, 3,   BAX↑, 27,   Bax:Bcl2↑, 8,   Bcl-2↓, 26,   Bcl-xL↓, 7,   BID↑, 2,   cl‑BID↑, 2,   BIM↑, 1,   BNIP3↝, 1,   BOK↑, 1,   Casp↓, 1,   Casp↑, 14,   Casp1↑, 1,   Casp12↑, 1,   cl‑Casp12↑, 1,   cl‑Casp12↝, 1,   Casp3↓, 1,   Casp3↑, 44,   cl‑Casp3↑, 12,   proCasp3↓, 1,   Casp6↑, 1,   Casp7↑, 4,   Casp8↑, 8,   cl‑Casp8↑, 1,   Casp9↑, 28,   cl‑Casp9↑, 4,   CellShr↑, 1,   Cupro↑, 1,   Cyt‑c↓, 1,   Cyt‑c↑, 33,   mt-Cyt‑c↓, 1,   Diablo↑, 2,   DR5↑, 5,   FADD↑, 2,   Fas↓, 1,   Fas↑, 6,   FasL↑, 1,   Ferroptosis↑, 9,   GranB/GZMB↝, 1,   GSDME-N↑, 1,   IAP1↓, 2,   ICD↑, 2,   iNOS↓, 2,   iNOS↑, 1,   Mcl-1↓, 3,   MDM2↓, 3,   MLKL↑, 1,   MOMP↑, 2,   NAIP↓, 1,   Necroptosis↑, 2,   necrosis↑, 3,   NOXA↑, 2,   p38↓, 1,   p38↑, 1,   p‑p38↑, 1,   Paraptosis↑, 1,   Perforin↝, 1,   PUMA↓, 1,   PUMA↑, 2,   Pyro↑, 3,   RIP3↑, 1,   p‑RIP3↑, 1,   survivin↓, 5,   TNFR 1↑, 1,   TumCD↑, 13,   XIAP↓, 2,   YAP/TEAD↓, 3,  

Kinase & Signal Transduction(tgid=6) ⓘ

Akt↓, 28,   Akt↑, 1,   p‑Akt↓, 8,   AKT1↓, 1,   Akt2↓, 1,   CaMKII ↓, 1,   CK2↓, 1,   p‑cMET↑, 1,   EGFR↓, 5,   ERK↓, 4,   ERK↑, 1,   p‑ERK↓, 1,   p‑ERK↑, 2,   FGFR1↓, 2,   FGFR2↓, 1,   HCAR2↑, 1,   HER2/EBBR2↓, 1,   Hippo↝, 1,   IGFR↓, 1,   JAK↓, 2,   JAK2↓, 2,   JNK↑, 2,   p‑JNK↑, 2,   MAPK↓, 5,   MAPK↑, 5,   mTOR↓, 15,   p‑mTOR↓, 5,   P70S6K↓, 1,   PDGFR-BB↑, 1,   PI3K↓, 18,   p‑PI3K↓, 1,   PI3K/Akt↓, 1,   PI3k/Akt/mTOR↓, 1,   PKA↓, 1,   PKCδ↓, 1,   PP2A↑, 1,   PRAS40↑, 1,   PTEN↑, 6,   p‑PTEN↓, 1,   RAS↓, 1,   p‑S6K↓, 1,   Sp1/3/4↓, 2,   STAT↓, 1,   STAT3↓, 15,   STAT3↑, 1,   p‑STAT3↓, 2,   THEM4/CTMP↑, 1,   TSC2↑, 1,  

Transcription & Epigenetics(tgid=7) ⓘ

ATF4↑, 5,   p‑ATF4↝, 1,   cJun↓, 1,   cMyc↓, 4,   DNMT3B↓, 1,   EZH2↓, 1,   FOXM1↓, 1,   FOXO↓, 1,   FOXO1↓, 1,   FOXO3↓, 2,   FOXO4↓, 1,   HDAC↓, 3,   HDAC8↓, 1,   miR-34a↑, 2,   MTA2↓, 1,   Myc↓, 1,   OCT4↓, 4,   other↝, 9,   PAX2↓, 1,   SOX2↓, 3,   SOX4↓, 2,   TCF-4↓, 1,   tumCV?, 1,   tumCV↓, 27,  

Protein Folding & ER Stress(tgid=8) ⓘ

ATF6↑, 1,   CHOP/DDIT3↑, 9,   p‑CHOP/DDIT3↝, 1,   CUL1↝, 1,   CUL5↝, 1,   eIF2α↓, 1,   eIF2α↑, 2,   p‑eIF2α↝, 1,   ER Stress↑, 28,   GRP78/BiP↑, 3,   HSF1↓, 1,   HSP90↓, 2,   IRE1↑, 1,   PERK↑, 3,   p‑PERK↝, 1,   UPR↑, 2,  

Autophagy & Lysosomes(tgid=9) ⓘ

ATG13↑, 1,   ATG16L1↑, 1,   ATG3↑, 1,   ATG5↑, 2,   ATG7↑, 2,   autolysosome↑, 1,   Beclin-1/ATG6↓, 1,   Beclin-1/ATG6↑, 7,   LC3‑Ⅱ/LC3‑Ⅰ↓, 1,   LC3‑Ⅱ/LC3‑Ⅰ↑, 5,   LC3A↑, 1,   LC3B↑, 1,   LC3II↓, 1,   LC3II↑, 5,   LC3s↑, 2,   MitoP↓, 1,   MitoP↑, 4,   p62↓, 3,   p62↑, 3,   p‑p62↑, 1,   PARK2↑, 4,   RUBCN↓, 1,   TumAuto↓, 2,   TumAuto↑, 24,   mt-TumAuto↑, 1,   ULK1/ATG1↑, 1,  

DNA Damage & Repair(tgid=10) ⓘ

ATR↑, 1,   DNAdam↑, 20,   hTERT/TERT↓, 4,   P53↑, 18,   P53↝, 1,   p‑P53↑, 3,   PARP↓, 2,   PARP↑, 3,   cl‑PARP↑, 15,   PCNA↓, 2,   Telomerase↓, 1,   TOP1↓, 2,   TOP2↓, 1,   TP53↓, 1,   γH2AX↑, 1,   p‑γH2AX↑, 1,  

Cell Cycle & Senescence(tgid=11) ⓘ

CC(CDKs/cyclins)↓, 1,   CDK1↓, 2,   CDK2↓, 7,   CDK4↓, 11,   CDK6↓, 4,   CDKN1C/p57↓, 1,   ChrCon↑, 1,   cycA1/CCNA1↓, 1,   CycB/CCNB1↓, 3,   cycD1/CCND1↓, 13,   cycE/CCNE↓, 3,   GADD45A↑, 1,   Ki-67↓, 5,   P21↓, 2,   P21↑, 12,   p27/CDKN1B↓, 1,   p27/CDKN1B↑, 2,   TumCCA↑, 52,  

Proliferation, Differentiation & Cell State(tgid=12) ⓘ

4E-BP1↓, 1,   ALDH↓, 3,   CD133↓, 1,   CD24↓, 1,   cFos↓, 1,   CSCs↓, 8,   CSCs↑, 1,   Diff↑, 1,   EIF4E↓, 2,   FGF↓, 1,   Gli1↓, 1,   HH↓, 2,   Ki-67↓, 5,   Let-7↑, 1,   mTORC1↓, 1,   Nanog↓, 5,   NOTCH1↓, 1,   PTCH1↓, 1,   Shh↓, 1,   STAT1↓, 2,   TumCG↓, 30,   TumCG↑, 1,   TumCP↓, 43,   TumCP↑, 1,   tyrosinase↓, 1,   Wnt↓, 6,  

Migration(tgid=13) ⓘ

Alix/AIP‑1↓, 2,   AP-1↓, 2,   BACH1↑, 1,   Ca+2↓, 2,   Ca+2↑, 17,   Ca+2↝, 1,   i-Ca+2↑, 2,   cal2↑, 1,   COL1↓, 1,   E-cadherin↓, 2,   E-cadherin↑, 11,   EMT↓, 16,   EMT↝, 1,   FAK↓, 2,   p‑FAK↑, 1,   Fibronectin↓, 1,   MMP-10↓, 1,   MMP2↓, 8,   MMP3↓, 2,   MMP7↓, 1,   MMP9↓, 10,   MMPs↓, 2,   N-cadherin↓, 7,   PAK1↓, 1,   PDGF↓, 1,   Slug↓, 2,   Smad1↓, 1,   Snail↓, 5,   TGF-β↓, 1,   TGF-β1↓, 1,   TIMP1↓, 1,   TIMP1↑, 1,   TIMP2↓, 1,   TSC1↑, 1,   TumCA↓, 1,   TumCA↑, 1,   TumCI↓, 16,   TumCMig↓, 20,   TumMeta↓, 10,   TumPF↓, 1,   Twist↓, 2,   uPA↓, 3,   uPAR↓, 1,   Vim↓, 8,   Zeb1↓, 4,   β-catenin/ZEB1↓, 5,  

Angiogenesis & Vasculature(tgid=14) ⓘ

angioG↓, 20,   CD31/PECAM-1↓, 1,   eNOS↑, 1,   Hif1a↓, 8,   Hif1a↑, 1,   Hypoxia↓, 1,   NO↓, 1,   NO↑, 3,   VCAM-1↓, 2,   VEGF↓, 13,   VEGFR1↓, 1,   VEGFR2/KDR/Flk1↓, 2,  

Barriers & Transport(tgid=15) ⓘ

BBB↑, 2,   BBB∅, 1,   CellMemb↓, 1,   CellMemb↑, 1,   CLDN1↓, 1,   CX43/GJA1↓, 1,   EPR↑, 1,   GLUT1↓, 2,   GLUT4↓, 1,   MMP?, 1,   MMP↓, 53,   MMP↑, 2,   MMP↝, 1,   MPT↓, 1,   MPT↑, 8,   TRPV1↑, 2,   TRPV2↑, 1,   ZO-1↑, 1,  

Immune & Inflammatory Signaling(tgid=16) ⓘ

CD4+↑, 1,   CD44↓, 3,   CD47↓, 1,   CD8+↑, 2,   cGAS–STING↑, 2,   COX2/PTGS2↓, 11,   CXCR4↓, 1,   DR4↑, 2,   Eos↑, 1,   HCAR2↑, 1,   HLA-I/II↑, 1,   HMGB1↓, 1,   ICAM-1↓, 3,   IL1↓, 1,   IL10↓, 2,   IL10↑, 1,   IL17↓, 1,   IL1β↓, 2,   IL2↑, 1,   IL4↓, 1,   IL6↓, 9,   IL8↓, 2,   Imm↑, 9,   Imm↝, 2,   Inflam↓, 6,   IRAK1↓, 1,   pol-M1↑, 1,   M2 MC↓, 1,   MCP1/CCL2↓, 3,   MIP2↓, 1,   Neut↑, 1,   NF-kB↓, 21,   NF-kB↑, 2,   NK cell↑, 2,   NLRP3↓, 2,   p65↓, 2,   PD-L1↓, 2,   PD-L1↑, 1,   PGE2↓, 2,   PSA↓, 2,   TCF↓, 2,   Th1 response↑, 1,   Th17↑, 1,   TLR4↓, 3,   TNF-α↓, 5,   TNF-α↑, 2,   TNFRSF25/DR3/APO3/LARD/TRAMP/WSL1↑, 1,   TRADD↑, 1,  

Cellular Microenvironment(tgid=17) ⓘ

e-pH↑, 1,  

Hormonal & Nuclear Receptors(tgid=20) ⓘ

AhR↓, 1,   AR↓, 1,   AR↑, 1,   PPARγ↓, 1,   RANKL↓, 1,  

Drug Metabolism & Resistance(tgid=21) ⓘ

ABC↓, 1,   ABCG2↓, 1,   AKR1B10↓, 1,   BioAv↓, 8,   BioAv↑, 5,   BioAv↝, 3,   BioEnh↑, 2,   ChemoSen↓, 1,   ChemoSen↑, 35,   Dose?, 2,   Dose↑, 1,   Dose↝, 25,   Dose∅, 4,   eff↓, 28,   eff↑, 32,   eff↝, 2,   eff∅, 1,   Half-Life↝, 3,   MDR1↓, 3,   MRP1/ABCC1↓, 1,   P-gp/ABCB1↓, 2,   RadioS↑, 6,   selectivity?, 1,   selectivity↓, 1,   selectivity↑, 39,   Synergy?, 1,   Synergy↑, 16,  

Clinical Biomarkers(tgid=22) ⓘ

ALAT↓, 3,   ALP↓, 1,   AR↓, 1,   AR↑, 1,   AST↓, 3,   EGFR↓, 5,   EZH2↓, 1,   FOXM1↓, 1,   HER2/EBBR2↓, 1,   hTERT/TERT↓, 4,   IL6↓, 9,   LDH↓, 8,   LDH↑, 2,   LDH↝, 1,   Myc↓, 1,   PD-L1↓, 2,   PD-L1↑, 1,   PSA↓, 2,   TP53↓, 1,   Tumccf↓, 1,  

Functional Outcomes(tgid=23) ⓘ

AntiCan↑, 10,   antiNeop↑, 1,   AntiTum↓, 1,   AntiTum↑, 9,   cachexia↓, 1,   CardioT↑, 1,   chemoP↑, 7,   chemoPv↑, 4,   ChemoSideEff↓, 1,   fatigue∅, 1,   hepatoP↓, 1,   hepatoP↑, 1,   neuroP↑, 1,   OS↑, 6,   QoL∅, 1,   radioP↑, 1,   RenoP↑, 1,   Risk↓, 1,   toxicity↓, 4,   toxicity↑, 3,   toxicity↝, 4,   TumVol↓, 3,   TumW↓, 1,   Weight↑, 1,  

Infection & Microbiome(tgid=24) ⓘ

GutMicro↑, 2,  

Ingredients & Constituents(tgid=25) ⓘ

Ingr↝, 6,  
Total Targets: 553

Pathway results for Effect on Normal Cells:


Redox & Oxidative Stress(tgid=1) ⓘ

antiOx↓, 3,   antiOx↑, 20,   ARE↑, 2,   Catalase↑, 13,   GPx↑, 7,   GPx4↑, 3,   GSH↑, 11,   GSH/GSSG↑, 1,   GSS↑, 1,   GSTs↑, 2,   H2O2↓, 1,   HO-1↑, 15,   Iron↓, 1,   i-Iron↓, 2,   Keap1↓, 2,   lipid-P↓, 14,   MDA↓, 12,   MPO↓, 3,   NQO1↑, 5,   Nrf1↑, 1,   NRF2↓, 1,   NRF2↑, 31,   Prx↓, 1,   ROS↓, 47,   ROS↑, 1,   ROS⇅, 2,   ROS↝, 1,   mt-ROS↓, 2,   SOD↑, 18,   SOD1↑, 1,   SOD2↑, 1,   TAC↑, 3,   TBARS↓, 2,   Trx↑, 1,   xCT/SLC7A11↑, 3,  

Metal & Cofactor Biology(tgid=2) ⓘ

IronCh↑, 1,  

Mitochondria & Bioenergetics(tgid=3) ⓘ

DRP1/DNM1L↓, 5,   DRP1/DNM1L↑, 1,   FIS1↓, 6,   MFN1↓, 1,   MFN1↑, 2,   MFN2↓, 1,   MFN2↑, 4,   mtDam↓, 37,   mtDam↑, 1,   OCR↓, 1,   OPA1↓, 1,   OPA1↑, 2,   PGC-1α↑, 3,   SIRT3↑, 1,   TFAM↑, 2,  

Core Metabolism/Glycolysis(tgid=4) ⓘ

ACSL4↓, 2,   ALAT↓, 3,   AMPK↑, 7,   ATP↑, 3,   ATP∅, 1,   CRM↑, 2,   glucose↓, 1,   GSK‐3β↓, 4,   LDHA↓, 1,   LDHA↑, 1,   LDL↓, 1,   NAD↑, 1,   NADPH↑, 2,   PKM2↓, 1,   SIRT1↑, 5,  

Cell Death(tgid=5) ⓘ

AIF↓, 2,   Apoptosis↓, 13,   ASC↓, 1,   BAX↓, 6,   Bax:Bcl2↓, 1,   Bcl-2↓, 1,   Bcl-2↑, 5,   Casp↓, 1,   cl‑Casp1↓, 1,   Casp3↓, 3,   cl‑Casp3↓, 3,   Casp9↓, 1,   cl‑Casp9↓, 1,   Cyt‑c↓, 3,   Ferroptosis↓, 5,   GSDMD↓, 1,   iNOS↓, 3,   p38↓, 1,   p38↑, 1,   p‑p38↓, 1,   Pyro↓, 1,  

Kinase & Signal Transduction(tgid=6) ⓘ

Akt↑, 1,   Akt↝, 1,   CaMKII ↓, 1,   CREB↑, 1,   p‑CREB↑, 1,   JNK↓, 3,   p‑JNK↓, 1,   MAPK↓, 1,   MAPK↝, 1,   mTOR↑, 1,   PI3K↑, 1,   STAT3↝, 1,  

Transcription & Epigenetics(tgid=7) ⓘ

AntiThr↑, 2,   p‑cJun↓, 1,   FOXO↑, 1,   FOXO3↑, 1,   other↑, 1,  

Protein Folding & ER Stress(tgid=8) ⓘ

CHOP/DDIT3↓, 1,   ER Stress↓, 6,   GRP78/BiP↓, 3,   HSP70/HSPA5↑, 1,   IRE1↓, 1,  

Autophagy & Lysosomes(tgid=9) ⓘ

Beclin-1/ATG6↓, 1,   LC3‑Ⅱ/LC3‑Ⅰ↓, 1,   MitoP↑, 1,  

DNA Damage & Repair(tgid=10) ⓘ

DNAdam↓, 2,  

Proliferation, Differentiation & Cell State(tgid=12) ⓘ

Diff↑, 1,   IGF-1↓, 1,   neuroG↑, 1,  

Migration(tgid=13) ⓘ

AntiAg↑, 3,   Ca+2↓, 4,   Ca+2↝, 1,   MMP9↓, 1,   MMPs↓, 1,   TGF-β↓, 1,   TGF-β↑, 1,   Vim↓, 1,  

Angiogenesis & Vasculature(tgid=14) ⓘ

CD31/PECAM-1↑, 1,   p‑eNOS↑, 1,   Hif1a↓, 1,   Hif1a↑, 1,   NO↓, 5,  

Barriers & Transport(tgid=15) ⓘ

BBB↑, 1,   BBB∅, 2,   GastroP↑, 1,   MMP↓, 2,   MMP↑, 4,   TJ↑, 1,   TRPC1↓, 1,  

Immune & Inflammatory Signaling(tgid=16) ⓘ

CB2 / CNR2↑, 1,   CD40↓, 1,   COX2/PTGS2↓, 6,   ICAM-1↓, 1,   IL10↓, 2,   IL10↑, 2,   IL17↓, 1,   IL18↓, 1,   IL1β↓, 7,   IL6↓, 7,   Inflam↓, 30,   IP-10/CXCL-10↓, 1,   NeuroI↓, 4,   NF-kB↓, 11,   NK cell↑, 1,   NLRP3↓, 5,   p65↓, 1,   PGE2↓, 1,   RAGE↓, 2,   SOCS-3↓, 1,   TLR4↓, 1,   TNF-α↓, 12,  

Cellular Microenvironment(tgid=17) ⓘ

GFAP↓, 2,  

Synaptic & Neurotransmission(tgid=18) ⓘ

Ach↑, 1,   AChE↓, 3,   AChE∅, 1,   BDNF↑, 6,   BDNF∅, 1,   ChAT↑, 1,   PSD95↑, 3,   RELN↑, 1,   SNAP25↑, 2,  

Protein Aggregation(tgid=19) ⓘ

APP↓, 3,   Aβ↓, 8,   Aβ42↓, 1,   BACE/β-secretase↓, 5,   IDE↑, 1,   PSEN1/PS1↓, 1,   p‑tau↓, 3,  

Hormonal & Nuclear Receptors(tgid=20) ⓘ

AHR↓, 1,   ER(estro)↓, 1,   PPARα↝, 1,   PPARγ↑, 1,   RAAS↓, 1,  

Drug Metabolism & Resistance(tgid=21) ⓘ

BioAv↓, 10,   BioAv↑, 5,   BioAv↝, 5,   CYP1A1↑, 1,   CYP1A2↑, 1,   CYP2E1↓, 1,   Dose↓, 1,   Dose↝, 5,   eff↓, 2,   eff↑, 9,   Half-Life↝, 1,   Synergy↑, 4,  

Clinical Biomarkers(tgid=22) ⓘ

ALAT↓, 3,   AST↓, 2,   BG↓, 1,   BloodF↑, 1,   BMD↑, 1,   BP↓, 2,   BP∅, 1,   BUN↓, 1,   creat↓, 3,   IL6↓, 7,   LDH↓, 2,   LDH↑, 1,   NOS2↓, 1,   RAGE↓, 2,   Urea↓, 2,  

Functional Outcomes(tgid=23) ⓘ

AntiAge↑, 1,   antiAll↑, 3,   AntiArt↑, 1,   AntiCan↓, 1,   AntiCan↑, 1,   AntiDiabetic↑, 4,   AntiTum↑, 1,   cardioP↑, 12,   chemoP↑, 2,   cognitive↑, 17,   hepatoP↑, 11,   Learn↑, 4,   memory↑, 15,   motorD↑, 1,   neuroP↓, 1,   neuroP↑, 24,   NP/CIPN↓, 1,   Obesity↓, 2,   OS↑, 1,   RenoP↑, 3,   Sleep↑, 1,   Stress↓, 1,   Stroke↓, 5,   Stroke↝, 1,   toxicity↓, 15,   toxicity↑, 1,   toxicity↝, 2,   Wound Healing↑, 1,  

Infection & Microbiome(tgid=24) ⓘ

AntiBio↑, 4,   AntiFungal↑, 1,   AntiP↑, 4,   AntiViral↑, 3,   Bacteria↓, 1,   GutMicro↑, 2,  
Total Targets: 241

Scientific Paper Hit Count for: mtDam, mitochondrial damage
14 Silver-NanoParticles
8 Ivermectin
6 Curcumin
6 Licochalcone A
5 Honokiol
5 Isobavachalcone
5 Luteolin
5 Propolis -bee glue
4 Phenethyl isothiocyanate
4 Resveratrol
4 EGCG (Epigallocatechin Gallate)
4 Lycopene
4 Selenite (Sodium)
3 3-bromopyruvate
3 Berberine
3 Betulinic acid
3 Capsaicin
3 Centella asiatica / Gotu kola → asiaticoside
3 Quercetin
3 Dandelion Root
3 Kaempferol
3 SonoDynamic Therapy UltraSound
3 Magnolol
3 Magnetic Fields
2 Allicin (mainly Garlic)
2 Apigenin (mainly Parsley)
2 NTP, Non-Thermal Plasma,Cold Atmospheric Plasma
2 Chlorogenic acid
2 chitosan
2 Chrysin
2 Copper and Cu NanoParticles
2 Ferulic acid
2 Diclofenac
2 Indole-3-carbinol
2 D-limonene
2 Electrical Pulses
2 Formononetin
2 Gallic acid
2 Gossypol/AT-101
2 Hydrogen Gas
2 doxorubicin
2 Hyperthermia
2 HydroxyTyrosol
2 Isoliquiritigenin
2 isoorientin
2 isoquercitrin
2 Linalool
2 Mangiferin
2 Melatonin
2 Phycocyanin
1 5-Aminolevulinic acid
1 Photodynamic Therapy
1 Astragalus
1 Glucose
1 entinostat
1 Alpha-Lipoic-Acid
1 Artemisinin
1 Ashwagandha(Withaferin A)
1 Berbamine
1 Radiotherapy/Radiation
1 Beta-Caryophyllene
1 bempedoic acid
1 Benzyl isothiocyanate
1 Allyl isothiocyanate
1 borneol
1 α-Bisabolol / Chamomile oil
1 Butyrate
1 Carvacrol
1 Cannabidiol
1 Celastrol
1 chaetocin
1 Cichoric acid / Chicoric acid
1 Cinnamon
1 Citric Acid
1 Crocetin
1 Cyclopamine
1 Cynaropicrin
1 Docosahexaenoic Acid
1 Dihydrocaffeic Acid
1 Diindolylmethane
1 Docetaxel
1 Disulfiram
1 Emodin
1 Fennel Oil/Foeniculum vulgare
1 Fisetin
1 Flaxseed Oil
1 Fucoidan
1 Gambogic Acid
1 Ginger/6-Shogaol/Gingerol
1 Graviola
1 Hibiscus sabdariffa
1 Hyperoside
1 Inulin Prebiotic
1 Isorhamnetin
1 Lapatinib
1 Cisplatin
1 Methylene blue
1 Matrine
1 Methyl Jasmonate
1 Magnetic Field Rotating
1 Morin
1 Mushroom Maitake
1 nicotinamide adenine dinucleotide
1 Bicarbonate(Sodium)
1 Nimbolide
1 Pachymic acid
1 Phenylbutyrate
1 Piperlongumine
1 Plumbagin
1 salinomycin
1 Sanguinarine
1 Selenium NanoParticles
1 Silymarin (Milk Thistle) silibinin
1 Shikonin
1 Spirulina(Arthrospira/Limnospira)
1 Selenium
1 Ursolic acid
1 Urolithin
1 Vitexin
1 Wogonin
Query results interpretion may depend on "conditions" listed in the research papers.
Such Conditions may include : 
  -low or high Dose
  -format for product, such as nano of lipid formations
  -different cell line effects
  -synergies with other products 
  -if effect was for normal or cancerous cells

Filter Conditions: Pro/AntiFlg:%  IllCat:%  CanType:%  Cells:%  prod#:%  Target#:614  State#:%  Dir#:%
  wNotes=0  sortOrder:rid,rpid

 

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