lactateProd Cancer Research Results

lactateProd, lactate production: Click to Expand ⟱
Source:
Type:
Lactate production has been linked to cancer development and progression. In normal conditions, lactate is produced in cells through a process called glycolysis, which breaks down glucose to generate energy. However, in cancer cells, this process is often upregulated, leading to increased lactate production, even in the presence of oxygen. This phenomenon is known as the Warburg effect.

-Lactate is the end product of glycolysis and induces TGFβ1 upregulation and the acidic microenvironment.


Scientific Papers found: Click to Expand⟱
2397- Wor,    Phytochemicals targeting glycolysis in colorectal cancer therapy: effects and mechanisms of action
- Review, Var, NA
lactateProd↓, GlucoseCon↓, GLUT3↓, HK2↓, PKM2↓, LDHA↓,
2414- β‐Ele,    Beta‐elemene inhibits breast cancer metastasis through blocking pyruvate kinase M2 dimerization and nuclear translocation
- in-vitro, BC, MDA-MB-231 - in-vitro, BC, MCF7 - in-vivo, NA, NA
TumCMig↓, TumCI↓, TumMeta↓, Glycolysis↓, GlucoseCon↓, lactateProd↓, PKM2↓, EGFR↓, GLUT1↓, LDHA↓, ECAR↓, OCR↓,
2425- γ-Toc,    Anticancer Effects of γ-Tocotrienol Are Associated with a Suppression in Aerobic Glycolysis
- in-vitro, Var, MCF7 - in-vivo, Var, NA
TumCG↓, GlucoseCon↓, ATP↓, lactateProd↓, Glycolysis↓, HK2↓, PFK↓, PKM2↓, LDHA↓, Akt↓, p‑mTOR↓, cMyc↓,

Showing Research Papers: 151 to 153 of 153
Prev Page 4 of 4

* indicates research on normal cells as opposed to diseased cells
Total Research Paper Matches: 153

Pathway results for Effect on Cancer / Diseased Cells:


Redox & Oxidative Stress(tgid=1) ⓘ

antiOx↓, 2,   antiOx↑, 2,   GPx↓, 1,   GPx↑, 1,   GPx4↓, 4,   GSH↓, 3,   GSH↑, 1,   GSH∅, 1,   GSH/GSSG↓, 1,   H2O2↑, 4,   HO-1↓, 1,   HO-1↑, 3,   HO-2↓, 1,   HO-2↑, 1,   Iron↑, 3,   i-Iron↑, 1,   lipid-P↓, 1,   lipid-P↑, 3,   MDA↑, 2,   i-MDA↑, 1,   NADH↓, 1,   NADPH/NADP+↓, 1,   NRF2↓, 2,   NRF2↑, 4,   ROS↓, 3,   ROS↑, 54,   ROS⇅, 2,   ROS↝, 1,   ROS∅, 2,   mt-ROS↑, 3,   RPM↑, 1,   SOD2↓, 1,   Trx1↓, 2,   TrxR↓, 2,   TrxR1↓, 1,   xCT/SLC7A11↓, 2,  

Metal & Cofactor Biology(tgid=2) ⓘ

Ferritin↓, 1,   FTH1↓, 1,   NCOA4↑, 1,  

Mitochondria & Bioenergetics(tgid=3) ⓘ

ADP:ATP↓, 1,   compI↓, 2,   CS↓, 1,   ETC↓, 1,   KIF2C↓, 1,   mitResp↓, 3,   mitResp↑, 2,   mtDam↑, 5,   OCR↓, 9,   OCR↑, 7,   OXPHOS↓, 3,   OXPHOS↑, 8,   mt-OXPHOS↑, 1,   PDH↓, 3,   PDH↑, 4,   PDH∅, 1,   p‑PDH↓, 2,   p‑PDH↑, 1,   SDH↑, 1,   VDAC1↓, 1,  

Core Metabolism/Glycolysis(tgid=4) ⓘ

ACC↓, 2,   ACSL1↓, 1,   ALAT↓, 1,   ALDOA↓, 2,   ALDOB↑, 1,   AminoA↓, 1,   AMPK↓, 1,   AMPK↑, 9,   p‑AMPK↑, 2,   ATP↓, 34,   ATP↑, 2,   ATP↝, 1,   i-ATP↓, 1,   ATP:AMP↓, 1,   CAIX/CA9↓, 1,   i-citrate↑, 1,   CPT1A↓, 1,   ECAR↓, 16,   ECAR↑, 1,   ECAR↝, 1,   ENO1↓, 3,   ENO3↑, 1,   FAO↓, 1,   FAO↑, 2,   FASN↓, 5,   FBP1↑, 2,   FDG↓, 1,   G6PD↓, 2,   GAPDH↓, 2,   GLO-I↓, 1,   GLS↓, 1,   glucose↓, 2,   glucose↑, 1,   GlucoseCon↓, 80,   GlucoseCon↑, 5,   GlucoseCon∅, 2,   glut↓, 1,   GlutaM↓, 1,   Glycolysis↓, 90,   Glycolysis↑, 5,   GSK‐3β↑, 1,   GSK‐3β↝, 1,   p‑GSK‐3β↓, 1,   HAGH/GLO2↓, 1,   HK1↓, 2,   HK2↓, 48,   HK2↑, 2,   HK3↑, 1,   HMG-CoA↓, 1,   lact/pyru↓, 1,   lactateProd↓, 136,   lactateProd↑, 7,   lactateProd↝, 1,   lactateProd∅, 2,   e-lactateProd↓, 1,   LAR↓, 1,   LDHA↓, 34,   LDHA↑, 1,   LDHA∅, 1,   lipoGen↓, 1,   MCT4↓, 5,   NAD↓, 1,   NAD↑, 1,   NADH:NAD↓, 1,   NADPH↓, 4,   PCK1↑, 1,   PDK1 / PDPK1?, 2,   PDK1 / PDPK1↓, 12,   p‑PDK1 / PDPK1↓, 2,   PDKs↓, 6,   PDKs↑, 1,   PFK↓, 5,   PFK1↓, 7,   PFK1↑, 1,   PFK2↓, 1,   PFKFB3↓, 1,   PFKP↓, 1,   PGK1↓, 2,   PGK2↑, 1,   PGM1↓, 1,   PGM1↑, 1,   PGM3↑, 1,   PKLR↑, 1,   PKM1↑, 2,   PKM2↓, 49,   PKM2↑, 1,   PKM2∅, 2,   p‑PKM2↓, 1,   PPP↓, 3,   PYGL↓, 1,   Pyruv↓, 3,   p‑S6↓, 1,   SCD1↓, 1,   SIRT1↓, 1,   SIRT1↑, 1,   SREBP2↓, 1,   TCA?, 1,   TCA↓, 2,   Warburg↓, 19,   Warburg↑, 3,  

Cell Death(tgid=5) ⓘ

AIF↑, 5,   Apoptosis↓, 1,   Apoptosis↑, 35,   ASC↑, 1,   BAD↑, 3,   Bak↑, 2,   BAX↑, 9,   Bax:Bcl2↑, 1,   Bcl-2↓, 11,   Bcl-xL↓, 3,   BIM↑, 1,   BNIP3↑, 1,   Casp↑, 5,   Casp1↓, 1,   Casp12↑, 1,   Casp3↑, 23,   cl‑Casp3↓, 1,   cl‑Casp3↑, 1,   proCasp3↓, 1,   Casp8↓, 1,   Casp8↑, 5,   Casp9↑, 10,   cFLIP↓, 1,   Cyt‑c↑, 12,   Cyt‑c↝, 2,   Diablo↑, 1,   DR5↑, 2,   Endon↑, 1,   FADD↑, 1,   Fas↑, 2,   Ferroptosis↑, 5,   GSDMC↑, 1,   GSDME-N↑, 1,   iNOS↓, 1,   Mcl-1↓, 2,   MDM2↓, 2,   MEG3↑, 1,   NOXA↑, 1,   p38↓, 1,   p38↑, 4,   proApCas↑, 1,   PUMA↑, 1,   Pyro↑, 2,   survivin↓, 3,   TumCD↑, 2,   TumCD∅, 1,   XIAP↓, 1,   YAP/TEAD↑, 2,  

Kinase & Signal Transduction(tgid=6) ⓘ

Akt↓, 22,   Akt↑, 3,   p‑Akt↓, 4,   p‑Akt↑, 1,   AKT1↓, 1,   AMPKα↓, 1,   CaMKII ↓, 1,   cMET↓, 1,   CREB↓, 1,   EGFR↓, 7,   ERK↓, 4,   ERK↑, 1,   ERK↝, 1,   p‑ERK↓, 2,   HER2/EBBR2↓, 1,   IGF-1R↑, 1,   IκB↑, 1,   p‑IκB↑, 1,   JAK↓, 1,   JNK↓, 1,   JNK↑, 5,   p‑JNK↑, 1,   MAPK↓, 1,   MAPK↑, 1,   MAPK↝, 1,   MARK4↓, 1,   mTOR↓, 19,   p‑mTOR↓, 2,   P70S6K↓, 1,   PFKFB2↓, 1,   PHKG1↑, 1,   PI3K↓, 11,   PI3K↑, 2,   PI3K/Akt↓, 1,   PI3k/Akt/mTOR↓, 1,   PKA↓, 4,   PKCδ↓, 1,   PTEN↑, 5,   RET↓, 1,   p‑S6K↓, 1,   SHP1↑, 1,   Sp1/3/4↓, 1,   p‑Src↓, 1,   STAT↓, 1,   STAT3↓, 11,   STAT3↑, 1,   p‑STAT3↓, 7,  

Transcription & Epigenetics(tgid=7) ⓘ

ATF4↑, 3,   cMyc↓, 15,   DNMTs↓, 1,   FOXM1↓, 1,   H3↓, 1,   H3K9↓, 1,   HDAC↓, 2,   HDAC2↓, 2,   HMTs↓, 2,   miR-155↓, 1,   miR-339-5p↑, 1,   miR-375↑, 1,   Myc↓, 4,   other↓, 2,   other↑, 1,   other↝, 4,   other∅, 1,   SOX2↓, 1,   SUV39H↓, 1,   TBX15↑, 1,   tumCV↓, 13,  

Protein Folding & ER Stress(tgid=8) ⓘ

CHOP/DDIT3↑, 3,   eIF2α↓, 1,   eIF2α↑, 2,   p‑eIF2α↑, 1,   ER Stress↑, 7,   GRP78/BiP↓, 1,   GRP78/BiP↑, 4,   HSP27↓, 1,   HSP70/HSPA5↓, 2,   HSP90↓, 2,   PERK↑, 3,   UPR↑, 4,  

Autophagy & Lysosomes(tgid=9) ⓘ

ATG5↑, 1,   ATG5↝, 1,   Beclin-1/ATG6↓, 1,   Beclin-1/ATG6↑, 2,   Beclin-1/ATG6↝, 1,   LC3‑Ⅱ/LC3‑Ⅰ↑, 1,   LC3B↑, 2,   LC3B-II↑, 2,   LC3II↑, 2,   LC3s↓, 1,   p62↑, 1,   TumAuto↑, 13,  

DNA Damage & Repair(tgid=10) ⓘ

ATM↑, 2,   p‑ATM↑, 2,   DNA-PK↑, 1,   DNAdam↓, 1,   DNAdam↑, 10,   hTERT/TERT↓, 2,   P53↑, 7,   p73↑, 1,   PARP↑, 1,   cl‑PARP↓, 1,   cl‑PARP↑, 9,   proPARP↓, 1,   PCNA↓, 1,   SIRT6↑, 2,   Telomerase↓, 1,   TOP1↓, 1,   TP53↓, 1,   γH2AX↑, 2,   p‑γH2AX↑, 1,  

Cell Cycle & Senescence(tgid=11) ⓘ

CDK1↓, 2,   CDK2↓, 4,   CDK4↓, 2,   CDK6↓, 3,   CDK8↓, 1,   Cyc↓, 1,   cycA1/CCNA1↓, 1,   cycA1/CCNA1↑, 1,   CycB/CCNB1↓, 3,   CycB/CCNB1↑, 1,   cycD1/CCND1↓, 8,   cycD1/CCND1↑, 1,   cycE/CCNE↓, 2,   cycE/CCNE↑, 1,   Ki-67↓, 7,   P21↓, 1,   P21↑, 5,   p27/CDKN1B↑, 2,   p‑RB1↓, 1,   TumCCA↓, 1,   TumCCA↑, 25,  

Proliferation, Differentiation & Cell State(tgid=12) ⓘ

ALDH↓, 1,   CD24↓, 1,   CSCs↓, 5,   Gli1↓, 2,   GTPBP4↓, 1,   HH↓, 1,   Ki-67↓, 7,   Let-7↑, 1,   mTORC1↓, 1,   Nanog↓, 1,   NOTCH↓, 1,   NOTCH1↓, 1,   NOTCH1↑, 1,   NOTCH3↓, 1,   TumCG↓, 33,   TumCG↑, 1,   TumCP↓, 41,   Wnt↓, 3,   Wnt↑, 1,   Wnt/(β-catenin)↓, 2,  

Migration(tgid=13) ⓘ

AP-1↓, 2,   AXL↓, 1,   Ca+2↓, 1,   Ca+2↑, 4,   Ca+2↝, 2,   CAFs/TAFs↓, 1,   Cav1↑, 1,   E-cadherin↑, 5,   EMT↓, 9,   p‑FAK↓, 1,   GIT1↓, 1,   MMP2↓, 8,   MMP3↓, 2,   MMP7↓, 1,   MMP9↓, 8,   MMP9:TIMP1↓, 1,   MMPs↓, 6,   N-cadherin↓, 3,   Rho↓, 1,   Slug↓, 2,   SMAD3↓, 1,   Snail?, 1,   Snail↓, 1,   TET1↑, 2,   TGF-β↓, 5,   TIMP1↑, 1,   TumCA↓, 1,   TumCI↓, 13,   TumCMig↓, 14,   TumMeta↓, 10,   TumPF↓, 1,   Twist↓, 4,   uPA↓, 2,   uPAR↓, 1,   Vim↓, 1,   Zeb1↓, 2,   Zeb1↑, 1,   ZEB2↓, 1,   α-SMA↓, 1,   α-SMA↑, 1,   β-catenin/ZEB1↓, 5,  

Angiogenesis & Vasculature(tgid=14) ⓘ

angioG↓, 5,   CD31/PECAM-1↓, 1,   Endoglin↑, 1,   HIF-1↓, 1,   Hif1a↓, 26,   Hif1a↑, 3,   Hypoxia↓, 1,   Hypoxia↑, 1,   LOX1↓, 1,   NO↓, 1,   NO↑, 4,   VEGF↓, 12,   VEGFR2/KDR/Flk1↓, 1,   VM↓, 1,  

Barriers & Transport(tgid=15) ⓘ

GLUT1↓, 32,   GLUT1↑, 2,   GLUT1∅, 1,   GLUT2↓, 3,   GLUT3↓, 2,   GLUT3∅, 1,   GLUT4↓, 2,   MMP↓, 21,   MMP↑, 1,   MPT↑, 2,   NHE1↓, 1,  

Immune & Inflammatory Signaling(tgid=16) ⓘ

CD44↓, 2,   COX1↓, 1,   COX2/PTGS2↓, 9,   COX2/PTGS2↑, 2,   HCAR1↓, 2,   ICAM-1↓, 1,   Igs↑, 1,   IL10↓, 1,   IL17↓, 1,   IL1β↓, 1,   IL4↓, 1,   IL6↓, 5,   IL6↑, 1,   Imm↑, 1,   Inflam↓, 5,   M2 MC↓, 1,   MCT1↓, 6,   NF-kB↓, 13,   NK cell↑, 2,   NLRP3↓, 1,   p‑p65↓, 1,   p‑p65↑, 1,   PD-L1↓, 2,   PGE2↓, 1,   RAGE↑, 1,   TLR4↓, 2,   TNF-α↓, 2,  

Cellular Microenvironment(tgid=17) ⓘ

pH↑, 3,   e-pH↑, 1,   i-pH↓, 2,  

Protein Aggregation(tgid=19) ⓘ

AGEs↑, 1,  

Hormonal & Nuclear Receptors(tgid=20) ⓘ

ER(estro)↓, 1,   PPARγ↑, 1,  

Drug Metabolism & Resistance(tgid=21) ⓘ

BioAv↓, 1,   BioAv↑, 9,   BioAv↝, 1,   BioEnh?, 1,   ChemoSen↑, 25,   Dose?, 1,   Dose↝, 15,   Dose∅, 3,   eff↓, 18,   eff↑, 22,   eff↝, 3,   GSTZ1↓, 1,   GSTZ1↝, 1,   Half-Life↓, 2,   Half-Life↝, 1,   Half-Life∅, 1,   MDR1↓, 1,   P-gp/ABCB1↓, 1,   P-gp/ABCB1↑, 1,   P-gp/ABCB1∅, 1,   RadioS↑, 10,   selectivity↓, 1,   selectivity↑, 21,   selectivity∅, 1,   Synergy↑, 26,  

Clinical Biomarkers(tgid=22) ⓘ

ALAT↓, 1,   AST↓, 1,   BG↓, 1,   BMD↑, 1,   E6↓, 1,   E7↓, 1,   EGFR↓, 7,   Ferritin↓, 1,   FOXM1↓, 1,   HER2/EBBR2↓, 1,   hTERT/TERT↓, 2,   IL6↓, 5,   IL6↑, 1,   LDH↓, 3,   LDH↑, 3,   LDH∅, 1,   Myc↓, 4,   PD-L1↓, 2,   RAGE↑, 1,   TP53↓, 1,  

Functional Outcomes(tgid=23) ⓘ

AntiCan↑, 3,   AntiTum↑, 2,   cachexia↓, 1,   cardioP↑, 1,   chemoP↑, 1,   chemoPv↑, 1,   fatigue↓, 1,   neuroP↑, 4,   NP/CIPN↑, 1,   OS↑, 4,   OS∅, 1,   Remission↑, 1,   Risk↓, 1,   Strength↑, 1,   toxicity↓, 2,   toxicity↑, 2,   toxicity↝, 6,   toxicity∅, 1,   TumVol↓, 7,   TumW↓, 5,   Weight∅, 1,  

Infection & Microbiome(tgid=24) ⓘ

GutMicro↑, 1,  
Total Targets: 525

Pathway results for Effect on Normal Cells:


Redox & Oxidative Stress(tgid=1) ⓘ

antiOx↑, 9,   mt-antiOx↑, 1,   Catalase↑, 4,   Copper↓, 1,   GPx↑, 4,   GSH↑, 6,   GSR↑, 2,   GSTs↑, 2,   HO-1↑, 2,   Iron↓, 1,   lipid-P↓, 2,   MDA↓, 2,   MPO↓, 1,   NRF2↑, 3,   Prx↑, 1,   ROS?, 1,   ROS↓, 12,   ROS↑, 1,   mt-ROS↑, 1,   SOD↑, 4,   Trx↑, 1,   VitC↑, 1,   VitE↑, 1,  

Mitochondria & Bioenergetics(tgid=3) ⓘ

ADP:ATP↓, 1,   OCR↑, 1,   OXPHOS↑, 1,   PGC-1α↑, 1,  

Core Metabolism/Glycolysis(tgid=4) ⓘ

ALAT↓, 1,   ATP↑, 3,   ECAR↓, 3,   ECAR∅, 1,   glucose↓, 1,   GlucoseCon↓, 3,   GlucoseCon↑, 1,   Glycolysis↓, 4,   Glycolysis↑, 1,   Glycolysis↝, 1,   HK2↓, 4,   lactateProd↓, 7,   LDHA↓, 2,   LDL↓, 1,   lipidLev↓, 1,   NADPH↓, 2,   PFK↓, 2,   PFK2↓, 1,   PFKP↓, 1,   PKM2↓, 4,   PPP↓, 2,  

Cell Death(tgid=5) ⓘ

Apoptosis↓, 1,   BAX↓, 1,   Casp3↓, 1,   Casp9↓, 1,   Cyt‑c↓, 1,   p38↓, 1,  

Kinase & Signal Transduction(tgid=6) ⓘ

Akt↓, 1,   CK2↓, 1,   p‑JNK↓, 1,   mTOR↓, 1,   PI3K↓, 1,  

Transcription & Epigenetics(tgid=7) ⓘ

other?, 1,  

Protein Folding & ER Stress(tgid=8) ⓘ

ER Stress↓, 1,  

Migration(tgid=13) ⓘ

AntiAg↑, 3,   Ca+2?, 1,  

Angiogenesis & Vasculature(tgid=14) ⓘ

Hif1a↓, 1,   Hif1a∅, 1,  

Barriers & Transport(tgid=15) ⓘ

BBB↑, 1,   MMP↓, 1,   MMP↑, 1,  

Immune & Inflammatory Signaling(tgid=16) ⓘ

COX1↓, 1,   COX2/PTGS2↓, 4,   CXCL1↓, 1,   HMGB1↓, 1,   IL1β↓, 3,   IL2↓, 1,   IL6↓, 2,   Inflam↓, 8,   NF-kB↓, 3,   PGE2↓, 1,   TNF-α↓, 3,  

Synaptic & Neurotransmission(tgid=18) ⓘ

5HT↑, 1,  

Protein Aggregation(tgid=19) ⓘ

Aβ↓, 2,  

Drug Metabolism & Resistance(tgid=21) ⓘ

BioAv↓, 4,   BioAv↑, 3,   BioAv↝, 1,   Dose↝, 2,   eff↑, 1,   eff↝, 1,   Half-Life↓, 1,   P450↑, 1,   selectivity↑, 2,  

Clinical Biomarkers(tgid=22) ⓘ

ALAT↓, 1,   AST↓, 1,   BG↓, 1,   IL6↓, 2,   LDH↓, 1,  

Functional Outcomes(tgid=23) ⓘ

AntiAge↑, 2,   antiAll↑, 1,   AntiDiabetic↑, 1,   cardioP↑, 5,   cognitive↑, 2,   hepatoP↑, 6,   memory↑, 3,   motorD↓, 1,   motorD↑, 1,   neuroP↑, 9,   Pain↓, 1,   RenoP↑, 1,   Strength↑, 1,   toxicity↓, 4,   toxicity↑, 1,   toxicity↝, 1,   toxicity∅, 3,  

Infection & Microbiome(tgid=24) ⓘ

GutMicro↑, 1,  
Total Targets: 113

Scientific Paper Hit Count for: lactateProd, lactate production
18 Shikonin
12 Dichloroacetate
8 Quercetin
8 Diclofenac
7 Resveratrol
5 EGCG (Epigallocatechin Gallate)
4 Artemisinin
4 Curcumin
4 Metformin
4 Kaempferol
4 Rosmarinic acid
3 Betulinic acid
3 Chrysin
3 Cisplatin
3 Methylene blue
3 Ursolic acid
3 Vitamin K2
2 Ashwagandha(Withaferin A)
2 Baicalein
2 Berberine
2 5-fluorouracil
2 chaetocin
2 Citric Acid
2 Radiotherapy/Radiation
2 Fenbendazole
2 Glabrescione B
2 lambertianic acid
2 Magnetic Fields
2 Methylglyoxal
2 Melatonin
2 Propolis -bee glue
2 Pterostilbene
2 Silymarin (Milk Thistle) silibinin
2 Thymoquinone
2 Vitamin C (Ascorbic Acid)
2 Vitamin D3
1 3-bromopyruvate
1 Astragalus
1 Allicin (mainly Garlic)
1 Alpha-Lipoic-Acid
1 DTS(dibenzyl trisulphide) from Anamu
1 Apigenin (mainly Parsley)
1 2-DeoxyGlucose
1 tamoxifen
1 Capsaicin
1 Catechins
1 Cichoric acid / Chicoric acid
1 Dichloroacetophenone(2,2-)
1 Bortezomib
1 salinomycin
1 Docosahexaenoic Acid
1 diet FMD Fasting Mimicking Diet
1 Chemotherapy
1 Ellagic acid
1 Gossypol/AT-101
1 Hydrogen Gas
1 Honokiol
1 Isoliquiritigenin
1 Isorhamnetin
1 Isovitexin
1 Matrine
1 Methyl Jasmonate
1 Magnetic Field Rotating
1 Oroxylin-A
1 Pachymic acid
1 Proanthocyanidins
1 Phenylbutyrate
1 Sulforaphane (mainly Broccoli)
1 Selenite (Sodium)
1 triptolide
1 Vitamin B1/Thiamine
1 Arsenic trioxide
1 Wogonin
1 Worenine
1 β‐Elemene
1 γ-Tocotrienol
Query results interpretion may depend on "conditions" listed in the research papers.
Such Conditions may include : 
  -low or high Dose
  -format for product, such as nano of lipid formations
  -different cell line effects
  -synergies with other products 
  -if effect was for normal or cancerous cells
Filter Conditions: Pro/AntiFlg:%  IllCat:%  CanType:%  Cells:%  prod#:%  Target#:739  State#:%  Dir#:%
wNotes=0 sortOrder:rid,rpid

 

Home Page