Inflam Cancer Research Results

Inflam, inflammation: Click to Expand ⟱
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Type:
Cancer and inflammation are closely linked, with chronic inflammation contributing to the development and progression of cancer. Various inflammatory mediators and cells are involved in this process.
Scientific Papers found: Click to Expand⟱
4273- BetA,    Betulinic acid, a natural PDE inhibitor restores hippocampal cAMP/cGMP and BDNF, improve cerebral blood flow and recover memory deficits in permanent BCCAO induced vascular dementia in rats
- in-vivo, NA, NA
*neuroP↑, *BDNF↑, *ROS↓, *Inflam↓, *cognitive↑,
4061- betaCar,  VitB12,  VitB6,  FA,  VitB3  Revisiting the Role of Vitamins and Minerals in Alzheimer’s Disease
- Review, AD, NA
*cognitive↑, *cognitive↑, *Inflam↓, *Hcy/homoC↓, *TNF-α↓, *other↝, *memory↑,
5626- Bif,    Bifidobacterium in anticancer immunochemotherapy: friend or foe?
- Review, Var, NA
*Inflam↓, *Treg lymp↑, *IL10?, Imm↑, eff↑,
5686- BJ,  BRU,    A review of Brucea javanica: metabolites, pharmacology and clinical application
- Review, Var, NA
AntiTum↑, other↝, ChemoSen↑, QoL↑, chemoP↑, *Inflam↓, NF-kB↓, TumCP↓, TumCI↓, TumMeta↓, Hif1a↓, NRF2↓, STAT3↓, COX2↓, Casp3↑, Casp9↑, ROS↑, EGFR↓, NRF2↑,
5482- BM,    Bacopa monnieri protects SH-SY5Y cells against tert-Butyl hydroperoxide-induced cell death via the ERK and PI3K pathways
- in-vitro, Nor, NA
*neuroP↑, *ERK↑, *Akt↑, *MAPK↑, *PI3K↑, *Inflam↓, antiOx↑,
5474- BM,    Pharmacological attributes of Bacopa monnieri extract: Current updates and clinical manifestation
*memory↑, *neuroP↑, *cognitive↑, *hepatoP↑, *antiOx↑, *AntiDiabetic↑, *fatigue↓, *GSK‐3β↓, *PI3K↑, *Akt↑, *tau↓, *ROS↓, *Inflam↓,
3693- BM,    Bacopa monnieri prevents colchicine-induced dementia by anti-inflammatory action
- in-vivo, AD, NA
*cognitive↑, *Aβ↓, *BACE↓, *Inflam↓, *ROS↓, *antiOx↑,
3692- BM,    Brahmi (Bacopa monnieri): An ayurvedic herb against the Alzheimer's disease
- Review, AD, NA
*neuroP↑, *ROS↓, *Inflam↓, *Aβ↓, *cognitive↑,
5680- BML,    Anticancer properties of bromelain: State-of-the-art and recent trends
- Review, Var, NA
*Inflam↓, *Bacteria↓, *Pain↓, *Diar↓, *Wound Healing↑, ERK↓, JNK↓, XIAP↓, HSP27↓, β-catenin/ZEB1↓, HO-1↓, lipid-P↓, ACSL4↑, ROS↑, SOD↑, Catalase↓, GSH↓, MDA↓, Casp3↓, Casp9↑, DNAdam↑, Apoptosis↑, NF-kB↓, P53↑, MAPK↓, APAF1↑, Cyt‑c↓, CD44↓, Imm↑, ATG5↑, LC3I↑, Beclin-1↑, IL2↓, IL4↓, IFN-γ↓, COX2↓, iNOS↓, ChemoSen↑, RadioS↑, Dose↝, other↓,
5677- BML,    Bromelain inhibits nuclear factor kappa-B translocation, driving human epidermoid carcinoma A431 and melanoma A375 cells through G(2)/M arrest to apoptosis
- in-vitro, Melanoma, A431 - in-vitro, Melanoma, A375
TumCP↓, Inflam↓, Akt↓, NF-kB↓, COX2↓, GSH↓, ROS↑, MMP↓, TumCCA↑, Apoptosis↑, ChemoSen↑,
5681- BML,    Supplementation Containing Bromelain on the Side Effects of Oncological Treatment: Systematic Review
- Review, Var, NA
Inflam↓, chemoP↑,
5656- BNL,    Role of borneol as enhancer in drug formulation: A review
- Review, Nor, NA - Review, Stroke, NA - Review, AD, NA
*eff↑, BBB↑, ChemoSen↑, *Inflam↓, *NO↓, *TNF-α↓, *IL6↓, *Bacteria↓, *eff↑, *Aβ↓, *SOD↑, *neuroP↑, *EPR↑, toxicity↓, P-gp↓, eff↑, other↝,
5669- BNL,    Comparison of pharmacological activity and safety of different stereochemical configurations of borneol: L-borneol, D-borneol, and synthetic borneol
- Review, Nor, NA - Review, AD, NA - Review, Stroke, NA
*eff↑, *eff↑, *toxicity↝, *Inflam↓, *Bacteria↓, *neuroP↑, *Half-Life↝, *BBB↑, *BioEnh↑, *P-gp↓, *CYP3A4↓, *ROS↓, *neuroP↑,
4272- Bor,    Neuroprotective properties of borax against aluminum hydroxide-induced neurotoxicity: Possible role of Nrf-2/BDNF/AChE pathways in fish brain
*NRF2↑, *ROS↓, *antiOx↑, *lipid-P↑, *Inflam↓, *DNAdam↓, *BDNF↑, *neuroP↑, *GSH↑,
4619- Bor,    Using Boron Supplementation in Cancer Prevention and Treatment: A Review Article
- Review, Var, NA
Dose↝, Risk↓, *antiOx↓, *Inflam↓, ChemoSen↑, AntiCan↑, *PCNA↓, *ROS↓, other↝,
696- Bor,    Nothing Boring About Boron
- Review, Var, NA
*hs-CRP↓, *TNF-α↓, *SOD↑, *Catalase↑, *GPx↑, *cognitive↑, *memory↑, *Risk↓, *SAM-e↑, *NAD↝, *ATP↝, *Ca+2↝, HDAC↓, TumVol↓, IGF-1↓, PSA↓, Cyc↓, TumCMig↓, *serineP↓, HIF-1↓, *ChemoSideEff↓, *VitD↑, *Mag↑, *eff↑, Risk↓, *Inflam↓, *neuroP↑, *Calcium↑, *BMD↑, *chemoP↑, AntiCan↑, *Dose↑, *Dose↝, *BMPs↑, *testos↑, angioG↓, Apoptosis↑, *selectivity↑, *chemoPv↑,
758- Bor,    Comparative effects of daily and weekly boron supplementation on plasma steroid hormones and proinflammatory cytokines
- Human, NA, NA
*hs-CRP↓, *TNF-α↓, *SHBG↓, *DHT↑, *cortisol↑, *VitD↑, *BioAv↑, *Inflam↓,
760- Bor,    Therapeutic Efficacy of Boric Acid Treatment on Brain Tissue and Cognitive Functions in Rats with Experimental Alzheimer’s Disease
- in-vivo, AD, NA
*memory↑, *ROS↓, *GSH↑, *Aβ↓, *Inflam↓, *MMP↑, *lipid-P↓, *Ca+2↓, *cognitive↑, *TOS↓,
730- Bor,  Cisplatin,    The Effect of Boric Acid and Borax on Oxidative Stress, Inflammation, ER Stress and Apoptosis in Cisplatin Toxication and Nephrotoxicity Developing as a Result of Toxication
- in-vivo, NA, NA
*ROS↓, *Inflam↓, RenoP↑,
3516- Bor,    Boron in wound healing: a comprehensive investigation of its diverse mechanisms
- Review, Wounds, NA
*Inflam↓, *antiOx↑, *ROS↓, *angioG↑, *COL1↑, *α-SMA↑, *TGF-β↑, *BMD↑, *hepatoP↑, *TNF-α↑, *HSP70/HSPA5↑, *SOD↑, *Catalase↑, *GSH↑, *MDA↓, *TOS↓, *IL6↓, *JAK2↓, *STAT3↓, *AMPK↑, *lipid-P↓, *VEGF↑, *Half-Life↝,
3511- Bor,    Boron
- Review, NA, NA
*memory↑, *motorD↑, *neuroP↑, Ca+2↓, ATF4↑, NRF2↑, *Inflam↓, *ROS↓,
3524- Bor,    Boric Acid Alleviates Lipopolysaccharide-Induced Acute Lung Injury in Mice
*Inflam↓, *SOD↑, *MDA↓, *GRP78/BiP↓, *CHOP/DDIT3↓, *NRF2↑, *HO-1↑,
3866- Bos,    Mechanistic role of boswellic acids in Alzheimer's disease: Emphasis on anti-inflammatory properties
- Review, AD, NA
*neuroP↑, *Inflam↓, *AChE↓, *Ach↑, *NRF2↑, *NF-kB↓, *Aβ↓,
3868- Bos,    Enhanced absorption of boswellic acids by a lecithin delivery form (Phytosome(®)) of Boswellia extract
*Inflam↓, *BioAv↓, *BioAv↑, *eff↑,
2777- Bos,    Inflammatory_Damage">Boswellia serrata Preserves Intestinal Epithelial Barrier from Oxidative and Inflammatory Damage
- in-vitro, IBD, NA
*p‑NF-kB↓, *ROS↓, Inflam↓,
2775- Bos,    The journey of boswellic acids from synthesis to pharmacological activities
- Review, Var, NA - Review, AD, NA - Review, PSA, NA
ROS↑, ER Stress↑, TumCG↓, Apoptosis↑, Inflam↓, ChemoSen↑, Casp↑, ERK↓, cl‑PARP↑, AR↓, cycD1/CCND1↓, VEGFR2/KDR/Flk1↓, CXCR4↓, radioP↑, NF-kB↓, VEGF↓, P21↑, Wnt↓, β-catenin/ZEB1↓, Cyt‑c↑, MMP2↓, MMP1↓, MMP9↓, PI3K↓, MAPK↓, JNK↑, *5LO↓, *NRF2↑, *HO-1↑, *MDA↓, *SOD↑, *hepatoP↑, *ALAT↓, *AST↓, *LDH↑, *CRP↓, *COX2↓, *GSH↑, *ROS↓, *Imm↑, *Dose↝, *eff↑, *neuroP↑, *cognitive↑, *IL6↓, *TNF-α↓,
2767- Bos,    The potential role of boswellic acids in cancer prevention and treatment
- Review, Var, NA
*Inflam↓, AntiCan↑, *MAPK↑, *Ca+2↝, p‑ERK↓, TumCI↓, cycD1/CCND1↓, cycE/CCNE↓, CDK2↓, CDK4↓, p‑RB1↓, *NF-kB↓, *TNF-α↓, NF-kB↓, IKKα↓, MCP1/CCL2↓, IL1α↓, MIP2↓, VEGF↓, Tf↓, COX2↓, MMP9↓, CXCR4↓, VEGF↓, eff↑, PPARα↓, lipid-P?, STAT3↓, TOP1↓, TOP2↑, 5HT↓, p‑PDGFR-BB↓, PDGF↓, AR↓, DR5↑, angioG↓, DR4↑, Casp3↑, Casp8↑, cl‑PARP↑, eff↑, chemoPv↑, Wnt↓, β-catenin/ZEB1↓, ascitic↓, Let-7↑, miR-200b↑, eff↑, MMP1↓, MMP2↓, eff↑, BioAv↓, BioAv↑, Half-Life↓, toxicity↓, Dose↑, BioAv↑, ChemoSen↑,
2768- Bos,    Boswellic acids as promising agents for the management of brain diseases
- Review, Var, NA - Review, AD, NA - Review, Park, NA
*neuroP↑, *ROS↓, *cognitive↓, TumCP↓, TumCMig↓, TumMeta↓, angioG↓, Apoptosis↑, *Inflam↓, IL1↓, IL2↓, IL4↓, IL6↓, TNF-α↓, P53↑, Akt↓, NF-kB↓, DNAdam↑, Casp↑, COX2↓, MMP9↓, CXCR4↓, VEGF↓, *SOD↑, *Catalase↑, *GPx↑, *NRF2↑,
2772- Bos,    Mechanistic role of boswellic acids in Alzheimer’s disease: Emphasis on anti-inflammatory properties
- Review, AD, NA
*neuroP↑, *Inflam↓, *AChE↓, *Choline↑, *NRF2↑, *NF-kB↑, *BBB↑, *BioAv↑, *Half-Life↓, *Dose↝, *PGE2↓, *ROS↓, *cognitive↑, *antiOx↑, 5LO↓, *TNF-α↓, *IL6↓, *HO-1↑,
2773- Bos,    Targeted inhibition of tumor proliferation, survival, and metastasis by pentacyclic triterpenoids: Potential role in prevention and therapy of cancer
- Review, Var, NA
Inflam↓, TumCCA↑, Casp3↑, Casp8↑, Casp9↑, STAT3↑, SHP1↓, NF-kB↓, cycD1/CCND1↓, COX2↓, Ki-67↓, CD31↓, IAP1↓, MMPs↓, Bcl-2↓, Bcl-xL↓,
5704- BRU,    Brusatol ameliorates psoriatic dyslipidemia by targeting IL-1β to restore AMPK-mediated lipid homeostasis
- in-vivo, PSA, HaCaT
*Inflam↓, *IL17↓, *TNF-α↓, *IL22↓, *STAT3↓, *other↝, *eff↑, *Dose?,
5705- Brut,    A flavonoid-rich extract from bergamot juice prevents carcinogenesis in a genetic model of colorectal cancer, the Pirc rat (F344/NTac-Apcam1137)
- in-vivo, CRC, NA
Risk↓, TumMeta↓, Apoptosis↑, COX2↓, iNOS↓, IL1β↓, IL6↓, IL10↓, P53↑, P21↓, survivin↓, chemoPv↑, *Inflam↓,
6549- BSB,    (-)-α-bisabolol prevents neuronal damage and memory deficits through reduction of proinflammatory markers induced by permanent focal cerebral ischemia in mice
- in-vivo, Nor, NA
*antiOx↑, Inflam↓, *Dose↝, *neuroP↑, *motorD↑, *memory↑, *MPO↓, *TNF-α↓, *iNOS↓,
6542- BSB,    Health Benefits, Pharmacological Effects, Molecular Mechanisms, and Therapeutic Potential of α-Bisabolol
- Review, Var, NA - Review, Park, NA - Review, AD, NA
AntiCan↑, *neuroP↑, *cardioP↑, *AntiBio↑, *BioAv↑, *toxicity↓, *BioAv↑, *motorD↑, *SOD↑, *Catalase↑, *Keap1↑, *MDA↓, *GSH↑, *IL1β↓, *IL6↓, *TNF-α↓, *iNOS↓, *COX2↓, *lipid-P↓, *Cyt‑c↓, *ROS↓, *MMP↑, *antiOx↑, *AChE↓, *Apoptosis↓, *BAX↓, *Casp3↓, *Bcl-2↑, *BACE↓, *BChE↓, *eff↑, *Aβ↓, *ATP↑, RadioS↑, Cyt‑c↑, Casp3↑, Casp8↑, Casp9↑, Apoptosis↑, PARP↑, BAX↑, BID↑, NF-kB↑, Fas↑, EGFR↑, TIMP2↑, XIAP↓, COX2↓, Bak↓, Bcl-2↓, P53↑, HER2/EBBR2↓, FGF↓, CEA↓, Akt↓, TumCCA↑, *Imm↑, *CD4+↑, *CD8+↑, *BBB↑, *Pain↓, *cardioP↑, *TBARS↓, *SOD↑, *Catalase↑, *GSH↑, *AntiBio↑, *AntiFungal↑, *GastroP↑, *RenoP↑, *creat↓, *uricA↓, *Inflam↓, *iNOS↓, *COX2↓, *TNF-α↓, *IL6↑, *MMP13↓,
6544- BSB,    Involvement of mitochondrial permeability transition pore opening in alpha-bisabolol induced apoptosis
- in-vitro, GBM, NA
*Inflam↓, *AntiBio↑, selectivity↑, Apoptosis↑, Casp3↑, cl‑PARP↑, MMP↓, Cyt‑c↑, MPT↑, ROS↑, eff↓, OCR↓, eff↑,
6552- BSB,    Biochemical characterization of chamomile essential oil: Antioxidant, antibacterial, anticancer and neuroprotective activity and potential treatment for Alzheimer's disease
- in-vivo, AD, NA
*TNF-α↓, *Aβ↓, *Casp3↓, *Bcl-2↓, *neuroP↑, *antiOx↑, *Inflam↓, *AntiBio↑, *AChE↓, *BChE↓, Dose↝, Dose↝, Dose↝,
6553- BSB,    Pharmacological and biological effects of alpha-bisabolol: An updated review of the molecular mechanisms
- Review, Nor, NA
*ROS↓, *Inflam↓, *Inf↓, *neuroP↑, *RNS↓, *MDA↓, *GSH↑, *MPO↓, *SOD↑, *Catalase↑, *Bcl-2↑, *BAX↓, *P53↓, *APAF1↓, *Casp3↓, *Casp9↓, *TNF-α↓, *IL1β↓, *IL6↓, *iNOS↓, *COX2↓, *ERK↓, *JNK↓, *NF-kB↓, *p38↓, *cognitive↑, *BChE↓,
6556- BSB,    A Comprehensive Study of Therapeutic Applications of Chamomile
- Review, Nor, NA - Review, AD, NA - Review, Park, NA - Review, Stroke, NA
*Inflam↓, *antiOx↑, *AntiBio↑, *hepatoP↑, *AntiCan↑, *other↝, *toxicity↓, *Wound Healing↓, *Dose↝, *Dose↝, *eff↝, *ROS↓, *TNF-α↓, *IL6↓, *other↝, *AST↓, *ALAT↓,
6557- BSB,    Alpha-bisabolol protects against neonatal asthma by suppressing airway inflammatory signaling
- in-vivo, Nor, NA
*ROS↓, *Inflam↓, *IL1β↓, *IL6↓, *IL8↓, *IL17↓, *CXCR4↓, *COX2↓, *TLR4↓, *NO↓, *MDA↓, *XO↓,
6560- BSB,  doxoR,    Α-Bisabolol, a Component of German Chamomile Tea Attenuates NLRP3 Inflammasome Mediated Pyroptosis, NF-ΚB/MAPK Signaling Activation and Apoptosis by Invoking NRF2 Mediated Antioxidant Defense Systems in Doxorubicin-Induced Liver Injury in Rats
- in-vivo, Nor, NA
*lipid-P↓, *antiOx↑, *Apoptosis↓, *Inflam↓,
5744- Buty,  PacT,    Oral sodium butyrate supplementation ameliorates paclitaxel-induced behavioral and intestinal dysfunction
- in-vivo, Var, NA
chemoP↑, neuroP↑, Inflam↓, GutMicro↑, *ROS↓, Dose↝,
5743- Buty,    Regulation of Intestinal Butyrate Transporters by Oxidative and Inflammatory Status
- Review, Var, NA
*GutMicro↑, *other↑, *Inflam↓, *ROS↓, AntiCan↑, HCAR2↑, HDAC↓,
5742- Buty,    Butyrate: A Double-Edged Sword for Health?
- Review, Var, NA
HCAR2↑, Inflam↓, HDAC↓, *IFN-γ↓, *TNF-α↓, *IL1β↓, *IL6↓, *IL8↓, *IL10↑, *LTA/TNF-β↑, *NF-kB↓, *ROS↓, PPARγ↓, Weight↓,
5740- Buty,    A Review of Nutritional Regulation of Intestinal Butyrate Synthesis: Interactions Between Dietary Polysaccharides and Proteins
- Review, RCC, NA
*eff↓, Dose↝, eff↑, HDAC↓, ac‑H3↓, ac‑H4↓, *HCAR2↑, *Inflam↓, *ROS↓, *NRF2↑, *GSH↑, *CLDN1↑, *ZO-1↑, IL1β↓, IL6↓, COX2↓, eff↝, eff↑, other↝,
5739- Buty,    Butyrate as a promising therapeutic target in cancer: From pathogenesis to clinic (Review)
- Review, Var, NA
GutMicro↑, *Inflam↓, *IL6↓, *TNF-α↓, *IL17↓, *IL10↑, *ROS↝, COX2↓, NLRP3↓, Imm↑, HDAC↓, TumCCA↑, Apoptosis↑, ROS↑, Casp↑, mtDam↑, Cyt‑c↑, eff↑, chemoP↑, ChemoSen↑, eff↑, RadioS↑, HCAR2↑,
5735- Buty,    Butyrate and the Intestinal Epithelium: Modulation of Proliferation and Inflammation in Homeostasis and Disease
- Study, Nor, NA
*Inflam↓, GutMicro↑, Imm↑,
5733- Buty,  VitB3,    Activation of Gpr109a, Receptor for Niacin and the Commensal Metabolite Butyrate, Suppresses Colonic Inflammation and Carcinogenesis
- in-vivo, CRC, NA
GutMicro↑, HCAR2↑, AntiCan↑, Inflam↓, IL18↑,
1650- CA,    Adjuvant Properties of Caffeic Acid in Cancer Treatment
- Review, Var, NA
ROS↑, antiOx↑, Inflam↓, AntiCan↑, NF-kB↓, STAT3↓, ERK↓, ChemoSen↑, RadioS↑, AMPK↑, eff↑, selectivity↑, COX2↓, Dose∅, PHDs↓, MMP9↓, MMP2↓, Dose∅, Dose∅, Ca+2↑, Dose?, MMP↓, RadioS↑,
3791- CA,    Caffeic Acid and Diseases—Mechanisms of Action
- Review, AD, NA
*memory↑, *cognitive↑, *p‑tau↓, *ROS↓, *Inflam↓, *NF-kB↓, *Casp3↓, *lipid-P↓, *AChE↓, *BChE↓, *GSK‐3β↓, *5LO↓, *BDNF↓, VEGF↓, HSP70/HSPA5↓,
5756- CA,    Experimental Evidence of Caffeic Acid’s Neuroprotective Activity in Alzheimer’s Disease: In Vitro, In Vivo, and Delivery-Based Insights
- vitro+vivo, AD, NA
*neuroP↑, *antiOx↑, *Inflam↓, *AChE↓, *BChE↓, *cognitive↑, *ROS↓, *Aβ↓, *tau↓, eff↑,

Showing Research Papers: 151 to 200 of 1007
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* indicates research on normal cells as opposed to diseased cells
Total Research Paper Matches: 1007

Pathway results for Effect on Cancer / Diseased Cells:


Redox & Oxidative Stress(tgid=1) ⓘ

antiOx↑, 2,   Catalase↓, 1,   GSH↓, 2,   HO-1↓, 1,   lipid-P?, 1,   lipid-P↓, 1,   MDA↓, 1,   NRF2↓, 1,   NRF2↑, 2,   ROS↑, 7,   SOD↑, 1,  

Metal & Cofactor Biology(tgid=2) ⓘ

Tf↓, 1,  

Mitochondria & Bioenergetics(tgid=3) ⓘ

MMP↓, 3,   MPT↑, 1,   mtDam↑, 1,   OCR↓, 1,   XIAP↓, 2,  

Core Metabolism/Glycolysis(tgid=4) ⓘ

ACSL4↑, 1,   AMPK↑, 1,   PPARα↓, 1,   PPARγ↓, 1,  

Cell Death(tgid=5) ⓘ

Akt↓, 3,   APAF1↑, 1,   Apoptosis↑, 9,   Bak↓, 1,   BAX↑, 1,   Bcl-2↓, 2,   Bcl-xL↓, 1,   BID↑, 1,   Casp↑, 3,   Casp3↓, 1,   Casp3↑, 5,   Casp8↑, 3,   Casp9↑, 4,   Cyt‑c↓, 1,   Cyt‑c↑, 4,   DR4↑, 1,   DR5↑, 1,   Fas↑, 1,   IAP1↓, 1,   iNOS↓, 2,   JNK↓, 1,   JNK↑, 1,   MAPK↓, 2,   survivin↓, 1,  

Kinase & Signal Transduction(tgid=6) ⓘ

HCAR2↑, 4,   HER2/EBBR2↓, 1,  

Transcription & Epigenetics(tgid=7) ⓘ

ac‑H3↓, 1,   ac‑H4↓, 1,   other↓, 1,   other↝, 4,  

Protein Folding & ER Stress(tgid=8) ⓘ

ER Stress↑, 1,   HSP27↓, 1,   HSP70/HSPA5↓, 1,  

Autophagy & Lysosomes(tgid=9) ⓘ

ATG5↑, 1,   Beclin-1↑, 1,   LC3I↑, 1,  

DNA Damage & Repair(tgid=10) ⓘ

DNAdam↑, 2,   P53↑, 4,   PARP↑, 1,   cl‑PARP↑, 3,  

Cell Cycle & Senescence(tgid=11) ⓘ

CDK2↓, 1,   CDK4↓, 1,   Cyc↓, 1,   cycD1/CCND1↓, 3,   cycE/CCNE↓, 1,   P21↓, 1,   P21↑, 1,   p‑RB1↓, 1,   TumCCA↑, 4,  

Proliferation, Differentiation & Cell State(tgid=12) ⓘ

CD44↓, 1,   ERK↓, 3,   p‑ERK↓, 1,   FGF↓, 1,   HDAC↓, 5,   IGF-1↓, 1,   Let-7↑, 1,   PI3K↓, 1,   SHP1↓, 1,   STAT3↓, 3,   STAT3↑, 1,   TOP1↓, 1,   TOP2↑, 1,   TumCG↓, 1,   Wnt↓, 2,  

Migration(tgid=13) ⓘ

5LO↓, 1,   Ca+2↓, 1,   Ca+2↑, 1,   CD31↓, 1,   CEA↓, 1,   Ki-67↓, 1,   miR-200b↑, 1,   MMP1↓, 2,   MMP2↓, 3,   MMP9↓, 4,   MMPs↓, 1,   PDGF↓, 1,   TIMP2↑, 1,   TumCI↓, 2,   TumCMig↓, 2,   TumCP↓, 3,   TumMeta↓, 3,   β-catenin/ZEB1↓, 3,  

Angiogenesis & Vasculature(tgid=14) ⓘ

angioG↓, 3,   ATF4↑, 1,   EGFR↓, 1,   EGFR↑, 1,   HIF-1↓, 1,   Hif1a↓, 1,   p‑PDGFR-BB↓, 1,   PHDs↓, 1,   VEGF↓, 5,   VEGFR2/KDR/Flk1↓, 1,  

Barriers & Transport(tgid=15) ⓘ

BBB↑, 1,   P-gp↓, 1,  

Immune & Inflammatory Signaling(tgid=16) ⓘ

COX2↓, 11,   CXCR4↓, 3,   HCAR2↑, 4,   IFN-γ↓, 1,   IKKα↓, 1,   IL1↓, 1,   IL10↓, 1,   IL18↑, 1,   IL1α↓, 1,   IL1β↓, 2,   IL2↓, 2,   IL4↓, 2,   IL6↓, 3,   Imm↑, 4,   Inflam↓, 10,   MCP1/CCL2↓, 1,   MIP2↓, 1,   NF-kB↓, 8,   NF-kB↑, 1,   PSA↓, 1,   TNF-α↓, 1,  

Synaptic & Neurotransmission(tgid=18) ⓘ

5HT↓, 1,  

Protein Aggregation(tgid=19) ⓘ

NLRP3↓, 1,  

Hormonal & Nuclear Receptors(tgid=20) ⓘ

AR↓, 2,  

Drug Metabolism & Resistance(tgid=21) ⓘ

BioAv↓, 1,   BioAv↑, 2,   ChemoSen↑, 9,   Dose?, 1,   Dose↑, 1,   Dose↝, 7,   Dose∅, 3,   eff↓, 1,   eff↑, 13,   eff↝, 1,   Half-Life↓, 1,   RadioS↑, 5,   selectivity↑, 2,  

Clinical Biomarkers(tgid=22) ⓘ

AR↓, 2,   ascitic↓, 1,   CEA↓, 1,   EGFR↓, 1,   EGFR↑, 1,   GutMicro↑, 4,   HER2/EBBR2↓, 1,   IL6↓, 3,   Ki-67↓, 1,   PSA↓, 1,  

Functional Outcomes(tgid=23) ⓘ

AntiCan↑, 7,   AntiTum↑, 1,   chemoP↑, 4,   chemoPv↑, 2,   neuroP↑, 1,   QoL↑, 1,   radioP↑, 1,   RenoP↑, 1,   Risk↓, 3,   toxicity↓, 2,   TumVol↓, 1,   Weight↓, 1,  
Total Targets: 174

Pathway results for Effect on Normal Cells:


NA, unassigned(tgid=0) ⓘ

AntiBio↑, 5,  

Redox & Oxidative Stress(tgid=1) ⓘ

antiOx↓, 1,   antiOx↑, 11,   Catalase↑, 6,   GPx↑, 2,   GSH↑, 8,   HO-1↑, 3,   Keap1↑, 1,   lipid-P↓, 5,   lipid-P↑, 1,   MDA↓, 6,   MPO↓, 2,   NRF2↑, 7,   RNS↓, 1,   ROS↓, 25,   ROS↝, 1,   SAM-e↑, 1,   SOD↑, 9,   TBARS↓, 1,   TOS↓, 2,   uricA↓, 1,  

Mitochondria & Bioenergetics(tgid=3) ⓘ

ATP↑, 1,   ATP↝, 1,   MMP↑, 2,  

Core Metabolism/Glycolysis(tgid=4) ⓘ

ALAT↓, 2,   AMPK↑, 1,   CYP3A4↓, 1,   LDH↑, 1,   NAD↝, 1,  

Cell Death(tgid=5) ⓘ

Akt↑, 2,   APAF1↓, 1,   Apoptosis↓, 2,   BAX↓, 2,   Bcl-2↓, 1,   Bcl-2↑, 2,   Casp3↓, 4,   Casp9↓, 1,   Cyt‑c↓, 1,   iNOS↓, 4,   JNK↓, 1,   MAPK↑, 2,   p38↓, 1,  

Kinase & Signal Transduction(tgid=6) ⓘ

HCAR2↑, 1,  

Transcription & Epigenetics(tgid=7) ⓘ

Ach↑, 1,   other↑, 1,   other↝, 4,  

Protein Folding & ER Stress(tgid=8) ⓘ

CHOP/DDIT3↓, 1,   GRP78/BiP↓, 1,   HSP70/HSPA5↑, 1,  

DNA Damage & Repair(tgid=10) ⓘ

DNAdam↓, 1,   P53↓, 1,   PCNA↓, 1,  

Proliferation, Differentiation & Cell State(tgid=12) ⓘ

Choline↑, 1,   ERK↓, 1,   ERK↑, 1,   GSK‐3β↓, 2,   PI3K↑, 2,   STAT3↓, 2,  

Migration(tgid=13) ⓘ

5LO↓, 2,   Ca+2↓, 1,   Ca+2↝, 2,   CLDN1↑, 1,   COL1↑, 1,   MMP13↓, 1,   serineP↓, 1,   TGF-β↑, 1,   Treg lymp↑, 1,   ZO-1↑, 1,   α-SMA↑, 1,  

Angiogenesis & Vasculature(tgid=14) ⓘ

angioG↑, 1,   EPR↑, 1,   NO↓, 2,   VEGF↑, 1,  

Barriers & Transport(tgid=15) ⓘ

BBB↑, 3,   GastroP↑, 1,   P-gp↓, 1,  

Immune & Inflammatory Signaling(tgid=16) ⓘ

CD4+↑, 1,   COX2↓, 5,   CRP↓, 1,   CXCR4↓, 1,   HCAR2↑, 1,   IFN-γ↓, 1,   IL10?, 1,   IL10↑, 2,   IL17↓, 3,   IL1β↓, 4,   IL22↓, 1,   IL6↓, 10,   IL6↑, 1,   IL8↓, 2,   Imm↑, 2,   Inflam↓, 40,   JAK2↓, 1,   LTA/TNF-β↑, 1,   NF-kB↓, 5,   NF-kB↑, 1,   p‑NF-kB↓, 1,   PGE2↓, 1,   TLR4↓, 1,   TNF-α↓, 16,   TNF-α↑, 1,   VitD↑, 2,  

Synaptic & Neurotransmission(tgid=18) ⓘ

AChE↓, 6,   BChE↓, 5,   BDNF↓, 1,   BDNF↑, 2,   tau↓, 2,   p‑tau↓, 1,  

Protein Aggregation(tgid=19) ⓘ

Aβ↓, 8,   BACE↓, 2,   XO↓, 1,  

Hormonal & Nuclear Receptors(tgid=20) ⓘ

cortisol↑, 1,   DHT↑, 1,   SHBG↓, 1,   testos↑, 1,  

Drug Metabolism & Resistance(tgid=21) ⓘ

BioAv↓, 1,   BioAv↑, 5,   BioEnh↑, 1,   Dose?, 1,   Dose↑, 1,   Dose↝, 6,   eff↓, 1,   eff↑, 9,   eff↝, 1,   Half-Life↓, 1,   Half-Life↝, 2,   selectivity↑, 1,  

Clinical Biomarkers(tgid=22) ⓘ

ALAT↓, 2,   AST↓, 2,   BMD↑, 2,   BMPs↑, 1,   Calcium↑, 1,   creat↓, 1,   CRP↓, 1,   GutMicro↑, 1,   Hcy/homoC↓, 1,   hs-CRP↓, 2,   IL6↓, 10,   IL6↑, 1,   LDH↑, 1,   Mag↑, 1,   VitD↑, 2,  

Functional Outcomes(tgid=23) ⓘ

AntiCan↑, 1,   AntiDiabetic↑, 1,   cardioP↑, 2,   chemoP↑, 1,   chemoPv↑, 1,   ChemoSideEff↓, 1,   cognitive↓, 1,   cognitive↑, 13,   fatigue↓, 1,   hepatoP↑, 4,   memory↑, 7,   motorD↑, 3,   neuroP↑, 19,   Pain↓, 2,   RenoP↑, 1,   Risk↓, 1,   toxicity↓, 2,   toxicity↝, 1,   Wound Healing↓, 1,   Wound Healing↑, 1,  

Infection & Microbiome(tgid=24) ⓘ

AntiFungal↑, 1,   Bacteria↓, 3,   CD8+↑, 1,   Diar↓, 1,   Inf↓, 1,  
Total Targets: 167

Scientific Paper Hit Count for: Inflam, inflammation
40 Curcumin
31 Magnetic Fields
30 Silymarin (Milk Thistle) silibinin
30 Quercetin
28 Thymoquinone
27 Hydrogen Gas
23 Resveratrol
18 Alpha-Lipoic-Acid
18 Berberine
18 Selenium NanoParticles
18 Fisetin
18 Rosmarinic acid
17 Lycopene
16 Ashwagandha(Withaferin A)
16 Ferulic acid
15 Capsaicin
15 Carvacrol
15 Sulforaphane (mainly Broccoli)
15 Urolithin
14 Propolis -bee glue
14 Emodin
13 Silver-NanoParticles
13 Beta-Caryophyllene
13 Eugenol
12 Apigenin (mainly Parsley)
12 Baicalein
12 Chlorogenic acid
12 Chrysin
11 Radiotherapy/Radiation
11 Cinnamon
11 Honokiol
10 Crocetin
10 Dandelion Root
10 EGCG (Epigallocatechin Gallate)
10 Pterostilbene
9 Selenite (Sodium)
9 Boron
9 Chemotherapy
9 Ginger/6-Shogaol/Gingerol
8 Astaxanthin
8 Boswellia (frankincense)
8 α-Bisabolol / Chamomile oil
8 Diclofenac
8 Fucoidan
8 Piperlongumine
8 Vitamin C (Ascorbic Acid)
8 Shikonin
7 Allicin (mainly Garlic)
7 Betulinic acid
7 Vitamin B3,Niacin
7 Butyrate
7 Centella asiatica / Gotu kola → asiaticoside
7 D-limonene
7 Gallic acid
6 1,8-Cineole
6 Artemisinin
6 Aspirin
6 Caffeic acid
6 Thymol-Thymus vulgaris
6 Garcinol
6 Magnolol
6 Piperine
6 Rutin
5 Folic Acid, Vit B9
5 Celastrol
5 chitosan
5 Chocolate
5 Coenzyme Q10
5 Ellagic acid
5 Shilajit/Fulvic Acid
5 Luteolin
5 Magnetic Field Rotating
5 Ursolic acid
4 Bacopa monnieri
4 Cisplatin
4 Caffeic Acid Phenethyl Ester (CAPE)
4 Cichoric acid / Chicoric acid
4 Hydroxycinnamic-acid
4 Carvone
4 Ginkgo biloba-EGb 761
4 Formononetin
4 Ginkgo biloba
4 Geraniol
4 Ginkgetin
4 Moringa oleifera
4 nicotinamide adenine dinucleotide
4 Nimbolide
4 Taurine
4 Vitamin B5,Pantothenic Acid
4 Vitamin D3
4 Vitamin K2
3 Anethole/trans-Anethole
3 Baicalin
3 Biochanin A
3 Vitamin B12
3 Bromelain
3 doxorubicin
3 Carnosine
3 Spermidine
3 Cucurbitacin
3 Date Fruit Extract
3 Docosahexaenoic Acid
3 eicosapentaenoic acid
3 diet Fermented Foods
3 Exercise
3 Gamma-aminobutyric acid
3 Genistein (soy isoflavone)
3 HydroxyCitric Acid
3 HydroxyTyrosol
3 Methylsulfonylmethane
3 α-Santalol/Sandalwood oil
3 Sulfasalazine
3 Vitamin B1/Thiamine
2 Anthocyanins
2 alpha Linolenic acid
2 Fennel Oil/Foeniculum vulgare
2 Melatonin
2 brusatol
2 borneol
2 Cat’s Claw
2 Celecoxib
2 Chlorophyllin
2 Choline
2 methotrexate
2 Selenium
2 Vitamin E
2 Galantamine
2 Huperzine A/Huperzia serrata
2 Lecithin
2 diet Short Term Fasting
2 Dipyridamole
2 Echinacea
2 Eurycomanone
2 flavonoids
2 Germanium Organic/Ge-132 / propagermanium (organogermanium)
2 Ginkgolide B
2 Ginseng
2 Orlistat
2 Potassium
2 Lutein
2 Methyl salicylate / Sweet Birch oil
2 Mushroom Lion’s Mane
2 Naringin
2 Oleocanthal
2 Phenylbutyrate
2 Phenethyl isothiocyanate
2 Phosphatidylserine
2 Salvia officinalis
2 Shankhpushpi
2 Salvia miltiorrhiza
2 Terpinen-4-ol / Tea Tree Oil
2 Aflavin-3,3′-digallate
2 Turmerones
1 2-DeoxyGlucose
1 5-Hydroxytryptophan
1 Astragalus
1 Acetyl-l-carnitine
1 Aloe anthraquinones
1 beta-glucans
1 xanthohumol
1 Cannabidiol
1 beta-carotene(VitA)
1 Vitamin B6,pyridoxine
1 Bifidobacterium
1 Brucea javanica
1 Bruteridin(bergamot juice)
1 Paclitaxel/Taxol
1 Carnosic acid
1 Cannabichromene
1 Cynanbungeigenin C (CBC) and D (CBD)
1 chaetocin
1 Prebiotic
1 Carica papaya leaf extract
1 Calorie Restriction Mimetics
1 Copper and Cu NanoParticles
1 Rivastigmine
1 Deguelin
1 Dihydrocaffeic Acid
1 Disulfiram
1 immunotherapy
1 Electrical Pulses
1 Evodiamine
1 Ascorbyl Palmitate
1 Flickering Light Stimulation
1 Iron
1 Galloflavin
1 Gambogic Acid
1 Ginkgolic acids
1 γ-linolenic acid (Borage Oil)
1 Germacranolide sesquiterpene lactone
1 Siegesbeckia glabrescens
1 hydrogen sulfide
1 Juglone
1 Licorice
1 Linalool
1 Zeaxanthin
1 5-fluorouracil
1 MCToil
1 Metformin
1 Neem
1 Oleuropein
1 Oregano
1 Peppermint
1 Propyl gallate
1 Psoralidin
1 Parthenolide
1 EMF
1 Radio Frequency
1 Aromatherapy
1 Gold NanoParticles
1 Sesame seeds and Oil
1 Silicic Acid
1 cetuximab
1 Terminalia bellirica
1 Thyme
1 Vitamin A, Retinoic Acid
1 Vitamin B2,Riboflavin
1 probiotics
1 Zinc
1 Zerumbone
Query results interpretion may depend on "conditions" listed in the research papers.
Such Conditions may include : 
  -low or high Dose
  -format for product, such as nano of lipid formations
  -different cell line effects
  -synergies with other products 
  -if effect was for normal or cancerous cells

Filter Conditions: Pro/AntiFlg:%  IllCat:%  CanType:%  Cells:%  prod#:%  Target#:953  State#:%  Dir#:%
  wNotes=0  sortOrder:rid,rpid

 

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