IL1β Cancer Research Results

IL1β, interleukin-1 beta: Click to Expand ⟱
Source:
Type:
The term "IL-1" is often used as an umbrella term for the interleukin-1 family, which includes multiple cytokines. The two best-known members are IL-1α and IL-1β.
IL-1β is secreted from cells and plays a major systemic role in inflammation. It is a crucial mediator in the inflammatory response and is involved in the fever response, activation of endothelial cells, and leukocyte recruitment.
Its increased expression is commonly linked to:
  – Promotion of a pro-inflammatory microenvironment that supports tumor growth.
  – Enhanced angiogenesis, invasion, and metastasis.
  – Recruitment of myeloid cells that may further suppress antitumor immunity.

High expression of either tends to be associated with a more aggressive phenotype and worse prognosis in many cancer types.


Scientific Papers found: Click to Expand⟱
3767- H2,    The role of hydrogen therapy in Alzheimer's disease management: Insights into mechanisms, administration routes, and future challenges
- Review, AD, NA
*Inflam↓, *neuroP↑, *toxicity↓, *antiOx↑, *ROS↓, *NLRP3↓, *IL1β↓, *mtDam↓, *ATP↑, *AMPK↑, *FOXO3↑, *SOD1↑, *Catalase↑, *NRF2↑, *NO↓, *MDA↓, *lipid-P↓, *memory↑, *ER(estro)↓, *BDNF↑, *cognitive↑, *APP↓, *BACE/β-secretase↓, *Aβ↓, *BP∅, *BBB↑,
2871- HNK,    Antihyperalgesic Properties of Honokiol in Inflammatory Pain Models by Targeting of NF-κB and Nrf2 Signaling
- in-vivo, Nor, NA
*TNF-α↓, *IL1β↓, *IL6↓, *VEGF↓, *NRF2↑, *SOD2↑, *HO-1↑, *Inflam↓, *Pain↓, *NO↓, toxicity↓,
2869- HNK,    Nature's neuroprotector: Honokiol and its promise for Alzheimer's and Parkinson's
- Review, AD, NA - Review, Park, NA
*neuroP↑, *Inflam↓, *motorD↑, *Aβ↓, *p‑tau↓, *cognitive↑, *memory↑, *ERK↑, *p‑Akt↑, *PPARγ↑, *PGC-1α↑, *MMP↑, *mt-ROS↓, *SIRT3↑, *IL1β↓, *TNF-α↓, *GRP78/BiP↓, *CHOP/DDIT3↓, *NF-kB↓, *GSK‐3β↓, *β-catenin/ZEB1↑, *Ca+2↓, *AChE↓, *SOD↑, *Catalase↑, *GPx↑,
2885- HNK,    Honokiol: a novel natural agent for cancer prevention and therapy
NF-kB↓, STAT3↓, EGFR↓, mTOR↓, BioAv↝, Inflam↓, TumCP↓, angioG↓, TumCI↓, TumMeta↓, cSrc↓, JAK1↓, JAK2↓, ERK↓, Akt↓, PTEN↑, ChemoSen↑, chemoP↑, COX2/PTGS2↓, PGE2↓, TNF-α↓, IL1β↓, IL6↓, Casp3↑, Casp8↑, Casp9↑, cl‑PARP↑, DNAdam↑, Cyt‑c↑, RadioS↑, RAS↓, BBB↑, BioAv↓, Half-Life↝, Half-Life↝, toxicity↓,
4238- HNK,    Neuropharmacological potential of honokiol and its derivatives from Chinese herb Magnolia species: understandings from therapeutic viewpoint
- Review, AD, NA - NA, Park, NA
*BDNF↑, *hepatoP↑, *ALAT↓, *AST↓, *TNF-α↓, *SIRT3↑, *Aβ↓, *Apoptosis↓, *ROS↓, *MMP↑, *Ca+2↓, *Casp3↓, *Ach↑, *PPARγ↑, *PGC-1α↑, *motorD↑, *TNF-α↓, *IL1β↓,
7569- HYP,    Inhibitory effects of hyperoside on lung cancer by inducing apoptosis and suppressing inflammatory response via caspase-3 and NF-κB signaling pathway
- vitro+vivo, Lung, A549
TumCP↓, TumCMig↓, TumCI↓, Casp3↑, Apoptosis↑, NF-kB↓, TNF-α↓, IL6↓, IL1β↓, IL18↓, TumVol↓, TumW↓,
7567- HYP,    Hyperoside: A review on its sources, biological activities, and molecular mechanisms
- Review, Var, NA
*AntiCan↑, *Bacteria↓, *AntiViral↑, *antiD↓, *RenoP↑, *hepatoP↑, *eff↑, *Sepsis↓, *AntiArt↑, *Stroke↓, TumCMig↓, TumCI↓, MTA1↓, TIMP2↓, MMP2↓, MMP↓, Cyt‑c↑, Akt↓, mTOR↓, P70S6K↓, TumAuto↑, PD-L1↓, TNF-α↓, IL1β↓, IL6↓, IL8↓, Bcl-2↓, Bcl-xL↓, BAX↑, BAD↑, Bak↑, VEGF↓, Casp3↑, Casp8↑, P53↑, GSH↓, SOD↓, Catalase↓, TAC↓, XIAP↓, ROS↓, NF-kB↓, TLR4↓, P-gp/ABCB1↓, LRP1↓, Fas↑, p27/CDKN1B↑, *cardioP↑, *AntiThr↑, *PAI-1/SERPINE1↓, *BUN↓, *ALAT↓, *AST↓, *neuroP?,
7565- HYP,    Potential Implications of Hyperoside on Oxidative Stress-Induced Human Diseases: A Comprehensive Review
- Review, AD, NA
*Inflam↓, *antiOx↑, *neuroP↑, *lipid-P↓, *ROS↓, *IL1β↓, *IL6↓, *IL8↓, *TNF-α↓, *MDA↓, *BAX↓, *Casp3↓, *Catalase↑, *SOD↑, *GSH↑, *BDNF↑, *TrkB↑, *NGF↑, *BDNF↑, *NF-kB↓, *AChE↓, *H2S↑, Casp3↑, Apoptosis↑, NF-kB↓, AMPK↑, HO-1↑, MAPK↑, cl‑Casp3↑, cl‑Casp9↑, BAX↑, SOD?, Catalase↓, NRF2↓, NQO1↓, HO-1↓, Bcl-2↓, TumCCA↑, FOXO1↑, TumAuto↑, Akt↓, mTOR↓, P70S6K↓, BMP7/OP1↓, *cardioP↑, *hepatoP↑, *antiCG↑, *AntiThr↑, *Diar↓, *AntiFungal↑, *CYP2D6↓, *PDGFR-BB↓, *PDGFRB↓, *toxicity↓, *Half-Life↑,
7563- HYP,    Hyperoside alleviates macrophages and microglia-mediated neuroinflammation and oxidative stress through activating PI3K/AKT and Nrf2/HO-1 signaling pathway post spinal cord injury
- vitro+vivo, Nor, NA
*Inflam↓, *antiOx↑, *Dose↝, *IL1β↓, *IL6↓, *TNF-α↓, *iNOS↓, *COX2/PTGS2↓, *NOX4↓, *NOX2↓, *NOX1↓, *PI3K↑, *Akt↑, *NRF2↑, *HO-1↑, *neuroP↑,
7560- HYP,    Hyperoside: A Review of Its Structure, Synthesis, Pharmacology, Pharmacokinetics and Toxicity
- Review, Nor, NA - Review, AD, NA
*RenoP↓, Casp3↑, Casp8↑, MDA↑, GSH↓, SOD↓, Catalase↓, VEGF↓, Bcl-2↓, TumCG↓, p‑Akt↓, PI3K↓, TumCCA↑, TumCP↓, BMP7/OP1↓, *ZO-1↑, *BBB↝, *p‑Akt↑, *GSK‐3β↑, *SOD↑, *Catalase↑, *GSH↑, *SIRT1↑, *NF-kB↓, *IL1β↓, *IL6↓, *IL8↓, *TNF-α↓, *ROS↓, *MDA↓, *BAX↓, *Casp3↓, *Bcl-2↑, *BDNF↑, *TrkB↑, *NGF↑, *Apoptosis↓, *cardioP↑, *AST↓, *hepatoP↑, *AST↓, *ALAT↓, *MDA↓, *BACH1↓, *neuroP↑, *Stroke↓, *ICAM-1↓, *VCAM-1↓, *TLR4↓, *COX2/PTGS2↓, *RenoP↑, *NLRP3↓, *Casp1↓, *ASC↓, *BioAv↓, *BioAv↑, *toxicity↓,
7779- ISL,    Isoliquiritigenin-mediated miR-23a-3p inhibition activates PGC-1α to alleviate alcoholic liver injury
- in-vivo, Alcohol, NA
*hepatoP↑, *FAM↑, *PGC-1α↑, *PPARα↑, *CPT1A↑, *ACADS/SCAD↑, *ROS↓, *TNF-α↓, *IL1β↓, *IL6↓, *miR-23a-3p↓,
7780- ISL,    Isoliquiritigenin alleviates LPS/ D-GalN-induced acute liver failure by activating the PGC-1α/ Nrf2 pathway to reduce oxidative stress and inflammatory response
- in-vivo, Nor, NA
*hepatoP↑, *ROS↓, *PGC-1α↝, *NRF2↑, *HO-1↑, *NQO1↝, *Keap1↝, *GCLC↝, *GCLM↝, *NLRP3↓, *IL1β↓, *IL6↓, *TNF-α↓, *MIP2↓, *Bax:Bcl2↓, *cl‑Casp3↓, *Inflam↓, *Apoptosis↓,
7781- ISL,    Perspectives on the Role of Isoliquiritigenin in Cancer
- Review, Var, NA
*BioAv↝, *BBB↓, *BioAv↑, selectivity↑, *neuroP↑, *Inflam↓, NF-kB↓, TNF-α↓, IL6↓, IL1β↓, IL10↓, ICAM-1↓, COX2/PTGS2↓, PPARγ↑, MMP2↓, cFos↓, VEGF↓, CHOP/DDIT3↓, CTSK↓, CycB/CCNB1↑, cycD1/CCND1↑, TOP2↑, PI3K↓, Akt↓, mTOR↓, MMP9↓, TIMP1↓, ChemoSen↑, CSCs↓,
7784- ISL,    Isoliquiritigenin attenuates lipopolysaccharide-induced cognitive impairment through antioxidant and anti-inflammatory activity
- in-vivo, AD, NA
*Learn↑, *PSD95↑, *BDNF↑, *SOD↑, *GPx↑, *Bcl-2↑, *SYP↑, *Bax:Bcl2↓, *TNF-α↓, *IL1β↓, *IL6↓, *MIP‑1α/CCL3↓, *p‑GSK‐3β↑, *NRF2↑, *HO-1↑, *NQO1↑, *cognitive↑, *Inflam↓,
7837- ISQ,    Isoquercitrin Delays Denervated Soleus Muscle Atrophy by Inhibiting Oxidative Stress and Inflammation
- in-vivo, Nor, NA
*Dose↝, *autophagy↓, *ATG7↓, *BNIP3↓, *LC3B↓, *PINK1↓, *ROS↓, *SOD1↑, *SOD2↑, *NRF2↑, *NQO1↑, *HO-1↑, *NOX2↓, *NOX4↓, *DUOX1↓, *IL1β↓, *IL6↓, *TNF-α↓, *JAK↓, *STAT3↓, *Inflam↓,
7812- ISQ,    Isoquercitrin promotes ferroptosis and oxidative stress in nasopharyngeal carcinoma via the AMPK/NF-κB pathway
- vitro+vivo, NPC, CNE1 - in-vitro, NPC, HNE1
tumCV↓, TumCP↓, ROS↑, lipid-P↑, NF-kB↓, MAPK↓, IL1β↓, TumCG↓, lipid-P↓, Ferroptosis↓, eff↓,
6482- LIN,    Pharmacological and molecular insights into linalool-rich Coriandrum sativum essential oil: Anticonvulsant, analgesic, anti-inflammatory, and antioxidant potential in rodent models
- Review, Nor, NA
IL1β↓, IL6↓, hepatoP↑, Inflam↓,
4292- LT,    Luteolin for neurodegenerative diseases: a review
- Review, AD, NA - Review, Park, NA - Review, MS, NA - Review, Stroke, NA
*Inflam↓, *antiOx↑, *neuroP↑, *BioAv↝, *BBB↑, *TNF-α↓, *IL1β↓, *IL6↓, *IL8↓, *IL33↓, *NF-kB↓, *BACE/β-secretase↓, *ROS↓, *SOD↑, *HO-1↑, *NRF2↑, *Casp3↓, *Casp9↑, *Bax:Bcl2↓, *UPR↑, *GRP78/BiP↑, *Aβ↓, *GSK‐3β↓, *tau↓, *CREB↑, *ATP↑, *cognitive↑, *BloodF↑, *BDNF↑, *TrkB↑, *memory↑, *PPARγ↑, *eff↑,
2921- LT,    Luteolin as a potential hepatoprotective drug: Molecular mechanisms and treatment strategies
- Review, Nor, NA
*hepatoP↑, *AMPK↑, *SIRT1↑, *ROS↓, STAT3↓, TNF-α↓, NF-kB↓, *IL2↓, *IFN-γ↓, *GSH↑, *SREBP1/SREBF1↓, *ZO-1↑, *TLR4↓, BAX↑, Bcl-2↓, XIAP↓, Fas↑, Casp8↑, Beclin-1↑, *TXNIP↓, *Casp1↓, *IL1β↓, *IL18↓, *NLRP3↓, *MDA↓, *SOD↑, *NRF2↑, *ER Stress↓, *ALAT↓, *AST↓, *iNOS↓, *IL6↓, *HO-1↑, *NQO1↑, *PPARα↑, *ATF4↓, *CHOP/DDIT3↓, *Inflam↓, *antiOx↑, *GutMicro↑,
2919- LT,    Luteolin as a potential therapeutic candidate for lung cancer: Emerging preclinical evidence
- Review, Var, NA
RadioS↑, ChemoSen↑, chemoP↑, *lipid-P↓, *Catalase↑, *SOD↑, *GPx↑, *GSTs↑, *GSH↑, *TNF-α↓, *IL1β↓, *Casp3↓, *IL10↑, NRF2↓, HO-1↓, NQO1↓, GSH↓, MET↓, p‑MET↓, p‑Akt↓, HGF/c-Met↓, NF-kB↓, Bcl-2↓, SOD2↓, Casp8↑, Casp3↑, PARP↑, MAPK↓, NLRP3↓, ASC↓, Casp1↓, IL6↓, IKKα↓, p‑p65↓, p‑p38↑, MMP2↓, ICAM-1↓, EGFR↑, p‑PI3K↓, E-cadherin↓, ZO-1↑, N-cadherin↓, CLDN1↓, β-catenin/ZEB1↓, Snail↓, Vim↑, ITGB1↓, FAK↓, p‑Src↓, Rac1↓, Cdc42↓, Rho↓, PCNA↓, Tyro3↓, AXL↓, CEA↓, NSE↓, SOD↓, Catalase↓, GPx↓, GSR↓, GSTs↓, GSH↓, VitE↓, VitC↓, CYP1A1↓, cFos↑, AR↓, AIF↑, p‑STAT6↓, p‑MDM2↓, NOTCH1↓, VEGF↓, H3↓, H4↓, HDAC↓, SIRT1↓, ROS↑, DR5↑, Cyt‑c↑, p‑JNK↑, PTEN↓, mTOR↓, CD34↓, FasL↑, Fas↑, XIAP↓, p‑eIF2α↑, CHOP/DDIT3↑, LC3II↑, PD-1↓, STAT3↓, IL2↑, EMT↓, cachexia↓, BioAv↑, *Half-Life↝, *eff↑,
3528- Lyco,    The Importance of Antioxidant Activity for the Health-Promoting Effect of Lycopene
- Review, Nor, NA - Review, AD, NA - Review, Park, NA
*antiOx↑, *ROS↓, *BioAv↝, *Half-Life↑, *BioAv↓, *BioAv↑, *cardioP↑, *neuroP↑, *H2O2↓, *VitC↑, *VitE↑, *GPx↑, *GSH↑, *MPO↓, *GSTs↓, *SOD↑, *NF-kB↓, *IL1β↓, *IL6↓, *IL10↑, *MAPK↓, *Akt↓, *COX2/PTGS2↓, *TNF-α↓, *TGF-β1↑, *NO↓, *GSR↑, *NRF2↑, *HO-1↑, *TAC↑, *Inflam↓, *BBB↑, *neuroP↑, *memory↑,
3264- Lyco,    Pharmacological potentials of lycopene against aging and aging‐related disorders: A review
- Review, Var, NA - Review, AD, NA - Review, Stroke, NA
*antiOx↑, *ROS↓, *SOD↑, *Catalase↑, *GSH↑, *GSTs↑, *MDA↓, *lipid-P↓, *NRF2↑, *HO-1↑, *iNOS↓, *NO↓, *TAC↑, *NOX4↓, *Inflam↓, *IL1↓, *IL6↓, *IL8↓, *IL1β↓, *TNF-α↓, *TLR2↓, *TLR4↓, *VCAM-1↓, *ICAM-1↓, *STAT3↓, *NF-kB↓, *ERK↓, *BP↓, ROS↓, PGE2↓, cardioP↑, *neuroP↑, *creat↓, *RenoP↑, *CRM↑,
3278- Lyco,    Anti-inflammatory effect of lycopene in SW480 human colorectal cancer cells
- in-vitro, Colon, SW480
TNF-α↓, IL1β↓, IL6↓, iNOS↓, COX2/PTGS2↓, PGE2↓, NO↓, NF-kB↓, JNK↓, Inflam↓, MPO↓,
1711- Lyco,    Nutritional Importance of Carotenoids and Their Effect on Liver Health: A Review
- Review, Var, NA
ROS↑, Dose↓, Dose↑, antiOx↑, P450↓, TNF-α↓, IL1β↓, IL12↓,
4230- Lyco,    Supplementation of lycopene attenuates oxidative stress induced neuroinflammation and cognitive impairment via Nrf2/NF-κB transcriptional pathway
- in-vivo, AD, NA
*BDNF↑, *antiOx↑, *Inflam↓, *HO-1↑, *NQO1↑, *IL1β↓, *TNF-α↓, *ROS↓, *NRF2↑, *cognitive↑, *BBB↑,
4781- Lyco,  5-FU,  Chemo,  Cisplatin,    Antioxidant and anti-inflammatory activities of lycopene against 5-fluorouracil-induced cytotoxicity in Caco2 cells
- in-vitro, Colon, Caco-2
chemoP↑, Inflam↓, COX2/PTGS2↓, IL1β↓, IL6↓, TNF-α↓, ROS↑, ChemoSen↑, SOD↓,
4782- Lyco,    New Insights into Molecular Mechanism behind Anti-Cancer Activities of Lycopene
- Review, Var, NA
AntiCan↑, TumCP↓, TumCMig↓, TumCI↓, TumCA↓, ROS↓, MMP2↓, MMP7↓, MMP9↓, VEGF↓, E-cadherin↑, TIMP1↑, TIMP2↑, BioAv↝, *IL12↓, *TNF-α↓, *IL1↓, *IL1β↓, *IL6↓, COX2/PTGS2↓, iNOS↓, *radioP↑, NF-kB↓, survivin↓, Casp3↑, Bax:Bcl2↑,
4801- Lyco,    Lycopene in the Prevention of Cardiovascular Diseases
- Review, CardioV, NA
*BioAv↝, *cardioP↑, *BioAv↑, *BioAv↑, *antiOx↑, *ROS↓, *ARE↑, *SOD↑, *Catalase↑, *GPx↑, *lipid-P↓, *COX2/PTGS2↓, *Inflam↓, *IL1β↓, *IL6↓, *IL8↑, *TNF-α↓, *NF-kB↓, *BP↓,
1779- MEL,    Therapeutic Potential of Melatonin Counteracting Chemotherapy-Induced Toxicity in Breast Cancer Patients: A Systematic Review
- Review, BC, NA
QoL↑, OS↑, Dose∅, antiOx↑, ROS↑, SOD↑, Catalase↑, GPx↑, Risk↓, NK cell↑, IL1β↓, IL6↓, TNF-α↓, radioP↑, chemoP↑, TumVol↓, TumMeta↓, angioG↓, ChemoSen↑, eff↑,
1777- MEL,    Melatonin as an antioxidant: under promises but over delivers
- Review, NA, NA
*ROS↓, *Fenton↓, *antiOx↑, *toxicity∅, *GPx↑, *GSR↑, *GSH↑, *NO↓, *Iron↓, *Copper↓, *IL1β↓, *iNOS↓, *Casp3↓, *BBB↑, *RenoP↑, chemoP↑, *Ca+2↝, eff↑, *PKCδ?, ChemoSen↑, eff↑, Akt↓, DR5↑, selectivity↑, ROS↑, eff↑,
2253- MF,    Low-frequency pulsed electromagnetic field promotes functional recovery, reduces inflammation and oxidative stress, and enhances HSP70 expression following spinal cord injury
- in-vivo, Nor, NA
*Inflam↓, *TNF-α↓, *IL1β↓, *NF-kB↓, *iNOS↓, *ROS↓, Catalase↑, *SOD↑, *HSP70/HSPA5↑, *neuroP↑, *motorD↑, *antiOx↑,
4116- MF,    Low‑frequency pulsed electromagnetic field promotes functional recovery, reduces inflammation and oxidative stress, and enhances HSP70 expression following spinal cord injury
- in-vivo, NA, NA
*Inflam↓, *TNF-α↓, *IL1β↓, *iNOS↓, *ROS↓, *Catalase↑, *SOD↑, HSP70/HSPA5↑,
3536- MF,    Targeting Mesenchymal Stromal Cells/Pericytes (MSCs) With Pulsed Electromagnetic Field (PEMF) Has the Potential to Treat Rheumatoid Arthritis
- Review, Arthritis, NA - Review, Stroke, NA
*Inflam↓, *Diff↑, *toxicity∅, *other↑, *SOX9↑, *COL2A1↑, *NO↓, *PGE2↓, *NF-kB↓, *TNF-α↓, *IL1β↓, *IL6↓, *IL10↑, *angioG↑, *MSCs↑, *VEGF↑, *TGF-β↑, *angioG↝, *VEGF↓, Ca+2↝,
3471- MF,    The prevention effect of pulsed electromagnetic fields treatment on senile osteoporosis in vivo via improving the inflammatory bone microenvironment
- in-vivo, Nor, NA
*BMD↑, *NLRP3↓, *proCasp1↓, *cl‑Casp1↓, *IL1β↓, *GSDMD↓,
3475- MF,    A Pulsed Electromagnetic Field Protects against Glutamate-Induced Excitotoxicity by Modulating the Endocannabinoid System in HT22 Cells
- in-vitro, Nor, HT22 - Review, AD, NA
*Apoptosis↓, *LDH↓, *neuroP↑, *toxicity∅, *IL1β↓, *Inflam↓, *IL10↑, *TNF-α↓,
3468- MF,    An integrative review of pulsed electromagnetic field therapy (PEMF) and wound healing
- Review, NA, NA
*other↑, *necrosis↓, *IL6↑, *TGF-β↑, *iNOS↑, *MMP2↑, *MCP1/CCL2↑, *HO-1↑, *Inflam↓, *IL1β↓, *IL6↓, *TNF-α↓, *BioAv↑, eff⇅, DNAdam↑, Apoptosis↑, ROS↑, TumCP↓, *ROS↓, *FGF↑,
3567- MFrot,  MF,    The Effect of Extremely Low-Frequency Magnetic Field on Stroke Patients: A Systematic Review
- Review, Stroke, NA
*eff↑, *ROS↓, *Inflam↓, *cognitive↑, *Catalase↑, *SOD↑, *SOD1↑, *SOD2↑, *GPx1↑, *GPx4↑, *IL1β↑, *neuroP↑, *toxicity∅,
3850- MSM,    The Influence of Methylsulfonylmethane on Inflammation-Associated Cytokine Release before and following Strenuous Exercise
- Human, NA, NA
*Inflam↓, *IL1β↓, *NF-kB↓, *NLRP3↓, *ROS↓,
4036- NAD,  VitB3,    NAD+ supplementation normalizes key Alzheimer’s features and DNA damage responses in a new AD mouse model with introduced DNA repair deficiency
- in-vivo, AD, NA
*Inflam↓, *p‑tau↓, *DNAdam↓, *memory↑, *motorD↑, *cognitive↑, *BBB↑, IL1β↓, *TNF-α↓, *MCP1/CCL2↓, *RANTES↓, *ROS↓, *SIRT3↑, *SIRT6↑,
1798- NarG,    Naringenin: A potential flavonoid phytochemical for cancer therapy
- Review, NA, NA
*Inflam↓, *antiOx↓, neuroP↑, hepatoP↑, AntiCan↑, Apoptosis↑, TumCCA↑, angioG↓, ROS↝, SOD↑, TGF-β↓, Treg lymp↓, IL1β↓, *BioAv↝, ChemoSen↑, cardioP↑,
6486- Nimb,    Nimbolide: promising agent for prevention and treatment of chronic diseases
- Review, Var, NA - Review, AD, NA
*other↝, *Inflam↓, AntiCan↑, *Bacteria↓, *AntiViral↑, *neuroP↑, *hepatoP↑, *ROS?, *NRF2↑, *HO-1↑, *TLR4↓, *NF-kB↓, *AChE↓, *Aβ↓, *GSK‐3β↓, *LDL↓, *DNAdam↓, *lipid-P↓, *antiOx↑, *SOD1↑, *GSH↑, *IL6↓, *IL1β↓, *STAT3↓, *GPx↑, *Catalase↑, *MDA↓, *AntiDiabetic↑, *HDL↓, *MCP1/CCL2↓, *VEGF↓, *MMP9↓, *GutMicro↑, TumCP↓, TumCCA↑, TumCMig↓, NF-kB↓, ROS↑, PI3K↓, Akt↓, mTOR↓, ERK↓, EMT↓, TumMeta↓, ChemoSen↑, eff↑, selectivity↑, CDK4↓, CDK6↓, Wnt↓, β-catenin/ZEB1↓, STAT3↓, MMP2↓, Sp1/3/4↓, AP-1↓, P21↑, *AntiArt↑, *IL23↓, *IL17↓, *IFN-γ↓, *HSP70/HSPA5↓,
4631- OLE,    Evidence to Support the Anti-Cancer Effect of Olive Leaf Extract and Future Directions
- Review, Var, NA
TumCP↓, *BioAv↑, *ROS↓, *NO↓, NF-kB↓, COX2/PTGS2↓, IL6↓, IL8↓, IL1β↓,
4647- OLEC,    Oleocanthal, an Antioxidant Phenolic Compound in Extra Virgin Olive Oil (EVOO): A Comprehensive Systematic Review of Its Potential in Inflammation and Cancer
- Review, Var, NA
*Inflam↓, AntiCan↑, *COX2/PTGS2↓, *ROS↓, *TNF-α↓, *IL1β↓, *iNOS↓, TumCP↓, *AntiAg↑, mTOR↓, STAT3↓, ERK↓, p‑Akt↓, Bcl-2↓, ROS↑, PSA↓,
2056- PB,    Endoplasmic Reticulum Stress Induces ROS Production and Activates NLRP3 Inflammasome Via the PERK-CHOP Signaling Pathway in Dry Eye Disease
- in-vitro, Nor, HCE-2
*ROS↓, *NLRP3↓, *IL1β↓, *TXNIP↑, *ER Stress↓,
2035- PB,    Sodium Phenylbutyrate Controls Neuroinflammatory and Antioxidant Activities and Protects Dopaminergic Neurons in Mouse Models of Parkinson’s Disease
- in-vitro, Nor, glial - in-vivo, NA, NA
*ROS↓, *Inflam↑, *P21↓, *antiOx↑, *GSH↑, *NF-kB↓, *neuroP↑, *HDAC↓, *iNOS↓, *TNF-α↓, *IL1β↓, *LDL↓, ROS↓,
2381- PBG,    Chinese Poplar Propolis Inhibits MDA-MB-231 Cell Proliferation in an Inflammatory Microenvironment by Targeting Enzymes of the Glycolytic Pathway
- in-vitro, BC, MDA-MB-231
TumCP↓, TumCMig↓, TumCI↓, angioG↓, TNF-α↓, IL1β↓, IL6↓, NLRP3↓, Glycolysis↓, HK2↓, PFK↓, PKM2↓, LDHA↓, ROS↑, MMP↓,
1682- PBG,    Honey, Propolis, and Royal Jelly: A Comprehensive Review of Their Biological Actions and Health Benefits
- Review, Var, NA
i-LDH↓, Akt↓, MAPK↓, NF-kB↓, IL1β↓, IL6↓, TNF-α↓, iNOS↓, COX2/PTGS2↓, ROS↓, Bcl-2↓, PARP↓, P53↑, BAX↑, Casp3↑, TumCCA↑, Cyt‑c↑, MMP↓, eff↑,
1663- PBG,    Propolis and Their Active Constituents for Chronic Diseases
- Review, Var, NA
NF-kB↓, Casp↓, Fas↓, DNAdam↑, Casp3↑, P53↝, MMP↝, ROS↑, mtDam↑, Dose?, angioG↓, TumCP↓, TumCMig↓, BAX↑, selectivity↑, MMP↓, LDH↓, IL6↓, IL1β↓, TNF-α↓,
1668- PBG,    Propolis: A Detailed Insight of Its Anticancer Molecular Mechanisms
- Review, Var, NA
antiOx↑, Inflam↓, AntiCan↑, TumCP↓, Apoptosis↑, eff↝, MMPs↓, TNF-α↓, iNOS↓, COX2/PTGS2↓, IL1β↑, *BioAv↓, BAX↑, Casp3↑, Cyt‑c↑, Bcl-2↓, eff↑, selectivity↑, P53↑, ROS↑, Casp↑, eff↑, ERK↓, Dose∅, TRAIL↑, NF-kB↑, ROS↑, Dose↑, MMP↓, DNAdam↑, TumAuto↑, LC3II↑, p62↓, EGF↓, Hif1a↓, VEGF↓, TLR4↓, GSK‐3β↓, NF-kB↓, Telomerase↓, ChemoSen↑, ChemoSideEff↓,
1231- PBG,    Caffeic acid phenethyl ester inhibits MDA-MB-231 cell proliferation in inflammatory microenvironment by suppressing glycolysis and lipid metabolism
- in-vitro, BC, MDA-MB-231
TumCP↓, TumCMig↓, TumCI↓, MMP↓, TLR4↓, TNF-α↓, NF-kB↓, IL1β↓, IL6↓, IRAK4↓, GLUT1↓, GLUT3↓, HK2↓, PFK↓, PKM2↓, LDHA↓, ACC↓, FASN↓, eff↓,

Showing Research Papers: 151 to 200 of 297
Prev Page 4 of 6 Next

* indicates research on normal cells as opposed to diseased cells
Total Research Paper Matches: 297

Pathway results for Effect on Cancer / Diseased Cells:


NA, unassigned(tgid=0)

BMP7/OP1↓, 2,   CTSK↓, 1,   MTA1↓, 1,  

Redox & Oxidative Stress(tgid=1)

antiOx↑, 3,   Catalase↓, 4,   Catalase↑, 2,   CYP1A1↓, 1,   Ferroptosis↓, 1,   GPx↓, 1,   GPx↑, 1,   GSH↓, 4,   GSR↓, 1,   GSTs↓, 1,   HO-1↓, 2,   HO-1↑, 1,   lipid-P↓, 1,   lipid-P↑, 1,   MDA↑, 1,   MPO↓, 1,   NQO1↓, 2,   NRF2↓, 2,   ROS↓, 5,   ROS↑, 13,   ROS↝, 1,   SOD?, 1,   SOD↓, 4,   SOD↑, 2,   SOD2↓, 1,   TAC↓, 1,   VitC↓, 1,   VitE↓, 1,  

Mitochondria & Bioenergetics(tgid=3)

AIF↑, 1,   EGF↓, 1,   MMP↓, 6,   MMP↝, 1,   mtDam↑, 1,   XIAP↓, 3,  

Core Metabolism/Glycolysis(tgid=4)

ACC↓, 1,   AMPK↑, 1,   FASN↓, 1,   Glycolysis↓, 1,   HK2↓, 2,   LDH↓, 1,   i-LDH↓, 1,   LDHA↓, 2,   PFK↓, 2,   PKM2↓, 2,   PPARγ↑, 1,   SIRT1↓, 1,  

Cell Death(tgid=5)

Akt↓, 7,   p‑Akt↓, 3,   Apoptosis↑, 5,   BAD↑, 1,   Bak↑, 1,   BAX↑, 6,   Bax:Bcl2↑, 1,   Bcl-2↓, 8,   Bcl-xL↓, 1,   Casp↓, 1,   Casp↑, 1,   Casp1↓, 1,   Casp3↑, 10,   cl‑Casp3↑, 1,   Casp8↑, 5,   Casp9↑, 1,   cl‑Casp9↑, 1,   Cyt‑c↑, 5,   DR5↑, 2,   Fas↓, 1,   Fas↑, 3,   FasL↑, 1,   Ferroptosis↓, 1,   HGF/c-Met↓, 1,   iNOS↓, 4,   JNK↓, 1,   p‑JNK↑, 1,   MAPK↓, 3,   MAPK↑, 1,   p‑MDM2↓, 1,   p27/CDKN1B↑, 1,   p‑p38↑, 1,   survivin↓, 1,   Telomerase↓, 1,   TRAIL↑, 1,  

Kinase & Signal Transduction(tgid=6)

cSrc↓, 1,   Sp1/3/4↓, 1,  

Transcription & Epigenetics(tgid=7)

H3↓, 1,   H4↓, 1,   tumCV↓, 1,  

Protein Folding & ER Stress(tgid=8)

CHOP/DDIT3↓, 1,   CHOP/DDIT3↑, 1,   p‑eIF2α↑, 1,   HSP70/HSPA5↑, 1,  

Autophagy & Lysosomes(tgid=9)

Beclin-1↑, 1,   LC3II↑, 2,   p62↓, 1,   TumAuto↑, 3,  

DNA Damage & Repair(tgid=10)

DNAdam↑, 4,   P53↑, 3,   P53↝, 1,   PARP↓, 1,   PARP↑, 1,   cl‑PARP↑, 1,   PCNA↓, 1,  

Cell Cycle & Senescence(tgid=11)

CDK4↓, 1,   CycB/CCNB1↑, 1,   cycD1/CCND1↑, 1,   P21↑, 1,   TumCCA↑, 5,  

Proliferation, Differentiation & Cell State(tgid=12)

CD34↓, 1,   cFos↓, 1,   cFos↑, 1,   CSCs↓, 1,   EMT↓, 2,   ERK↓, 4,   FOXO1↑, 1,   GSK‐3β↓, 1,   HDAC↓, 1,   mTOR↓, 7,   NOTCH1↓, 1,   P70S6K↓, 2,   PI3K↓, 3,   p‑PI3K↓, 1,   PTEN↓, 1,   PTEN↑, 1,   RAS↓, 1,   p‑Src↓, 1,   STAT3↓, 5,   p‑STAT6↓, 1,   TOP2↑, 1,   TumCG↓, 2,   Wnt↓, 1,  

Migration(tgid=13)

AP-1↓, 1,   AXL↓, 1,   Ca+2↝, 1,   Cdc42↓, 1,   CEA↓, 1,   CLDN1↓, 1,   E-cadherin↓, 1,   E-cadherin↑, 1,   FAK↓, 1,   ITGB1↓, 1,   LRP1↓, 1,   MET↓, 1,   p‑MET↓, 1,   MMP2↓, 5,   MMP7↓, 1,   MMP9↓, 2,   MMPs↓, 1,   N-cadherin↓, 1,   Rac1↓, 1,   Rho↓, 1,   Snail↓, 1,   TGF-β↓, 1,   TIMP1↓, 1,   TIMP1↑, 1,   TIMP2↓, 1,   TIMP2↑, 1,   Treg lymp↓, 1,   TumCA↓, 1,   TumCI↓, 6,   TumCMig↓, 7,   TumCP↓, 13,   TumMeta↓, 3,   Tyro3↓, 1,   Vim↑, 1,   ZO-1↑, 1,   β-catenin/ZEB1↓, 2,  

Angiogenesis & Vasculature(tgid=14)

angioG↓, 5,   EGFR↓, 1,   EGFR↑, 1,   Hif1a↓, 1,   NO↓, 1,   VEGF↓, 6,  

Barriers & Transport(tgid=15)

BBB↑, 1,   GLUT1↓, 1,   GLUT3↓, 1,   P-gp/ABCB1↓, 1,  

Immune & Inflammatory Signaling(tgid=16)

ASC↓, 1,   COX2/PTGS2↓, 8,   ICAM-1↓, 2,   IKKα↓, 1,   IL10↓, 1,   IL12↓, 1,   IL18↓, 1,   IL1β↓, 17,   IL1β↑, 1,   IL2↑, 1,   IL6↓, 14,   IL8↓, 2,   Inflam↓, 5,   IRAK4↓, 1,   JAK1↓, 1,   JAK2↓, 1,   NF-kB↓, 16,   NF-kB↑, 1,   NK cell↑, 1,   p‑p65↓, 1,   PD-1↓, 1,   PD-L1↓, 1,   PGE2↓, 3,   PSA↓, 1,   TLR4↓, 3,   TNF-α↓, 14,  

Protein Aggregation(tgid=19)

NLRP3↓, 2,  

Hormonal & Nuclear Receptors(tgid=20)

AR↓, 1,   CDK6↓, 1,  

Drug Metabolism & Resistance(tgid=21)

BioAv↓, 1,   BioAv↑, 1,   BioAv↝, 2,   ChemoSen↑, 9,   Dose?, 1,   Dose↓, 1,   Dose↑, 2,   Dose∅, 2,   eff↓, 2,   eff↑, 8,   eff⇅, 1,   eff↝, 1,   Half-Life↝, 2,   P450↓, 1,   RadioS↑, 2,   selectivity↑, 5,  

Clinical Biomarkers(tgid=22)

AR↓, 1,   CEA↓, 1,   EGFR↓, 1,   EGFR↑, 1,   IL6↓, 14,   LDH↓, 1,   i-LDH↓, 1,   NSE↓, 1,   PD-L1↓, 1,   PSA↓, 1,  

Functional Outcomes(tgid=23)

AntiCan↑, 5,   cachexia↓, 1,   cardioP↑, 2,   chemoP↑, 5,   ChemoSideEff↓, 1,   hepatoP↑, 2,   neuroP↑, 1,   OS↑, 1,   QoL↑, 1,   radioP↑, 1,   Risk↓, 1,   toxicity↓, 2,   TumVol↓, 2,   TumW↓, 1,  
Total Targets: 247

Pathway results for Effect on Normal Cells:


NA, unassigned(tgid=0)

ACADS/SCAD↑, 1,   AntiArt↑, 2,   antiCG↑, 1,   antiD↓, 1,   autophagy↓, 1,   CYP2D6↓, 1,   DUOX1↓, 1,   FAM↑, 1,   Learn↑, 1,   miR-23a-3p↓, 1,   NOX1↓, 1,   NOX2↓, 2,   Stroke↓, 2,   SYP↑, 1,  

Redox & Oxidative Stress(tgid=1)

antiOx↓, 1,   antiOx↑, 13,   ARE↑, 1,   Catalase↑, 10,   Copper↓, 1,   Fenton↓, 1,   GCLC↝, 1,   GCLM↝, 1,   GPx↑, 7,   GPx1↑, 1,   GPx4↑, 1,   GSH↑, 9,   GSR↑, 2,   GSTs↓, 1,   GSTs↑, 2,   H2O2↓, 1,   HDL↓, 1,   HO-1↑, 12,   Iron↓, 1,   Keap1↝, 1,   lipid-P↓, 6,   MDA↓, 7,   MPO↓, 1,   NOX4↓, 3,   NQO1↑, 4,   NQO1↝, 1,   NRF2↑, 12,   ROS?, 1,   ROS↓, 24,   mt-ROS↓, 1,   SIRT3↑, 3,   SOD↑, 13,   SOD1↑, 4,   SOD2↑, 3,   TAC↑, 2,   VitC↑, 1,   VitE↑, 1,  

Mitochondria & Bioenergetics(tgid=3)

ATP↑, 2,   MMP↑, 2,   mtDam↓, 1,   PGC-1α↑, 3,   PGC-1α↝, 1,   PINK1↓, 1,  

Core Metabolism/Glycolysis(tgid=4)

ALAT↓, 4,   AMPK↑, 2,   ATG7↓, 1,   BUN↓, 1,   CPT1A↑, 1,   CREB↑, 1,   CRM↑, 1,   H2S↑, 1,   LDH↓, 1,   LDL↓, 2,   PPARα↑, 2,   PPARγ↑, 3,   SIRT1↑, 2,   SREBP1/SREBF1↓, 1,  

Cell Death(tgid=5)

Akt↓, 1,   Akt↑, 1,   p‑Akt↑, 2,   Apoptosis↓, 4,   BAX↓, 2,   Bax:Bcl2↓, 3,   Bcl-2↑, 2,   Casp1↓, 2,   cl‑Casp1↓, 1,   proCasp1↓, 1,   Casp3↓, 6,   cl‑Casp3↓, 1,   Casp9↑, 1,   GSDMD↓, 1,   iNOS↓, 8,   iNOS↑, 1,   MAPK↓, 1,   necrosis↓, 1,  

Kinase & Signal Transduction(tgid=6)

SOX9↑, 1,  

Transcription & Epigenetics(tgid=7)

Ach↑, 1,   AntiThr↑, 2,   other↑, 2,   other↝, 1,  

Protein Folding & ER Stress(tgid=8)

CHOP/DDIT3↓, 2,   ER Stress↓, 2,   GRP78/BiP↓, 1,   GRP78/BiP↑, 1,   HSP70/HSPA5↓, 1,   HSP70/HSPA5↑, 1,   UPR↑, 1,  

Autophagy & Lysosomes(tgid=9)

BNIP3↓, 1,   LC3B↓, 1,  

DNA Damage & Repair(tgid=10)

DNAdam↓, 2,   SIRT6↑, 1,  

Cell Cycle & Senescence(tgid=11)

P21↓, 1,  

Proliferation, Differentiation & Cell State(tgid=12)

Diff↑, 1,   ERK↓, 1,   ERK↑, 1,   FGF↑, 1,   FOXO3↑, 1,   GSK‐3β↓, 3,   GSK‐3β↑, 1,   p‑GSK‐3β↑, 1,   HDAC↓, 1,   MSCs↑, 1,   PDGFRB↓, 1,   PI3K↑, 1,   STAT3↓, 3,  

Migration(tgid=13)

AntiAg↑, 1,   APP↓, 1,   BACH1↓, 1,   Ca+2↓, 2,   Ca+2↝, 1,   COL2A1↑, 1,   MMP2↑, 1,   MMP9↓, 1,   PAI-1/SERPINE1↓, 1,   PKCδ?, 1,   TGF-β↑, 2,   TGF-β1↑, 1,   TXNIP↓, 1,   TXNIP↑, 1,   VCAM-1↓, 2,   ZO-1↑, 2,   β-catenin/ZEB1↑, 1,  

Angiogenesis & Vasculature(tgid=14)

angioG↑, 1,   angioG↝, 1,   ATF4↓, 1,   NO↓, 7,   PDGFR-BB↓, 1,   VEGF↓, 3,   VEGF↑, 1,  

Barriers & Transport(tgid=15)

BBB↓, 1,   BBB↑, 6,   BBB↝, 1,  

Immune & Inflammatory Signaling(tgid=16)

ASC↓, 1,   COX2/PTGS2↓, 5,   ICAM-1↓, 2,   IFN-γ↓, 2,   IL1↓, 2,   IL10↑, 4,   IL12↓, 1,   IL17↓, 1,   IL18↓, 1,   IL1β↓, 31,   IL1β↑, 1,   IL2↓, 1,   IL23↓, 1,   IL33↓, 1,   IL6↓, 17,   IL6↑, 1,   IL8↓, 4,   IL8↑, 1,   Inflam↓, 26,   Inflam↑, 1,   JAK↓, 1,   MCP1/CCL2↓, 2,   MCP1/CCL2↑, 1,   MIP‑1α/CCL3↓, 1,   MIP2↓, 1,   NF-kB↓, 12,   PGE2↓, 1,   RANTES↓, 1,   TLR2↓, 1,   TLR4↓, 4,   TNF-α↓, 26,  

Synaptic & Neurotransmission(tgid=18)

AChE↓, 3,   BDNF↑, 8,   NGF↑, 2,   PSD95↑, 1,   tau↓, 1,   p‑tau↓, 2,   TrkB↑, 3,  

Protein Aggregation(tgid=19)

Aβ↓, 5,   BACE/β-secretase↓, 2,   NLRP3↓, 7,  

Hormonal & Nuclear Receptors(tgid=20)

ER(estro)↓, 1,  

Drug Metabolism & Resistance(tgid=21)

BioAv↓, 3,   BioAv↑, 7,   BioAv↝, 5,   Dose↝, 2,   eff↑, 4,   Half-Life↑, 2,   Half-Life↝, 1,  

Clinical Biomarkers(tgid=22)

ALAT↓, 4,   AST↓, 5,   BloodF↑, 1,   BMD↑, 1,   BP↓, 2,   BP∅, 1,   creat↓, 1,   GutMicro↑, 2,   IL6↓, 17,   IL6↑, 1,   LDH↓, 1,  

Functional Outcomes(tgid=23)

AntiCan↑, 1,   AntiDiabetic↑, 1,   cardioP↑, 5,   cognitive↑, 7,   hepatoP↑, 8,   memory↑, 5,   motorD↑, 4,   neuroP?, 1,   neuroP↑, 15,   Pain↓, 1,   radioP↑, 1,   RenoP↓, 1,   RenoP↑, 4,   toxicity↓, 3,   toxicity∅, 4,  

Infection & Microbiome(tgid=24)

AntiFungal↑, 1,   AntiViral↑, 2,   Bacteria↓, 2,   Diar↓, 1,   Sepsis↓, 1,  
Total Targets: 226

Scientific Paper Hit Count for: IL1β, interleukin-1 beta
18 Thymoquinone
12 Sulforaphane (mainly Broccoli)
10 Propolis -bee glue
10 Hydrogen Gas
10 Quercetin
8 Curcumin
8 Lycopene
7 Magnetic Fields
7 Silymarin (Milk Thistle) silibinin
6 Alpha-Lipoic-Acid
6 Resveratrol
6 Shikonin
6 Urolithin
5 Silver-NanoParticles
5 Beta-Caryophyllene
5 Chrysin
5 Crocetin
5 Hyperoside
4 Ashwagandha(Withaferin A)
4 Baicalein
4 Berberine
4 Eugenol
4 Ferulic acid
4 Chemotherapy
4 Honokiol
4 Isoliquiritigenin
4 Rosmarinic acid
3 1,8-Cineole
3 α-Bisabolol / Chamomile oil
3 Carvacrol
3 Celastrol
3 Centella asiatica / Gotu kola → asiaticoside
3 Chlorogenic acid
3 Cichoric acid / Chicoric acid
3 Dandelion Root
3 Radiotherapy/Radiation
3 EGCG (Epigallocatechin Gallate)
3 Fisetin
3 Formononetin
3 Gallic acid
3 Luteolin
3 Piperine
3 Rutin
3 Vitamin C (Ascorbic Acid)
2 Allicin (mainly Garlic)
2 Phyllanthus emblica/Emblica officinalis/Amla / Indian Gooseberry
2 Apigenin (mainly Parsley)
2 Artemisinin
2 Baicalin
2 Betulinic acid
2 borneol
2 Boron
2 Boswellia (frankincense)
2 Butyrate
2 Capsaicin
2 Thymol-Thymus vulgaris
2 Echinacea
2 D-limonene
2 Emodin
2 Cisplatin
2 Phosphatidylserine
2 Fucoidan
2 Ginkgo biloba
2 isoquercitrin
2 5-fluorouracil
2 Melatonin
2 Phenylbutyrate
2 Piperlongumine
2 Pterostilbene
1 Anthocyanins
1 alpha Linolenic acid
1 Anethole/trans-Anethole
1 Fennel Oil/Foeniculum vulgare
1 Atorvastatin
1 Aloe anthraquinones
1 Biochanin A
1 xanthohumol
1 Selenium
1 Bruteridin(bergamot juice)
1 Carnosic acid
1 Carnosine
1 chitosan
1 Chyawanprash
1 Carvone
1 Cynara scolymus/Globe Artichoke/Artichoke Extract
1 Date Fruit Extract
1 Docosahexaenoic Acid
1 Dihydrocaffeic Acid
1 Vitamin A, Retinoic Acid
1 eicosapentaenoic acid
1 methotrexate
1 Folic Acid, Vit B9
1 Fenbendazole
1 Gamma-aminobutyric acid
1 Galloflavin
1 Geraniol
1 Ginger/6-Shogaol/Gingerol
1 Ginseng
1 Linalool
1 Magnetic Field Rotating
1 Methylsulfonylmethane
1 nicotinamide adenine dinucleotide
1 Vitamin B3,Niacin
1 Naringin
1 Nimbolide
1 Oleuropein
1 Oleocanthal
1 Psoralidin
1 Perilla
1 α-Santalol/Sandalwood oil
1 Selenium NanoParticles
1 Sesame seeds and Oil
1 acetaminophen
1 Terpinen-4-ol / Tea Tree Oil
1 Vitamin B1/Thiamine
1 Vitamin B5,Pantothenic Acid
1 Vitamin D3
1 Vitamin K2
1 Zeaxanthin
1 Lutein
Query results interpretion may depend on "conditions" listed in the research papers.
Such Conditions may include : 
  -low or high Dose
  -format for product, such as nano of lipid formations
  -different cell line effects
  -synergies with other products 
  -if effect was for normal or cancerous cells
Filter Conditions: Pro/AntiFlg:%  IllCat:%  CanType:%  Cells:%  prod#:%  Target#:978  State#:%  Dir#:%
wNotes=0 sortOrder:rid,rpid

 

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