Cancer Database Query Results

Scientific Papers found: Click to Expand⟱
414- CUR,    Transcriptome Investigation and In Vitro Verification of Curcumin-Induced HO-1 as a Feature of Ferroptosis in Breast Cancer Cells
- in-vitro, BC, MCF-7 - in-vitro, BC, MDA-MB-231
Ferroptosis↑, Iron↑, ROS↑, lipid-P↑, MDA↑, GSH↓, HO-1↑, NRF2↑, GPx↓, ROS↑, Iron↑, GPx4↓, HSP70/HSPA5↑, ATFs↑, CHOP↑, MDA↑, FTL↑, FTH1↑, BACH1↑, REL↑, USF1↑, NFE2L2↑,
437- CUR,    Anti-cancer activity of amorphous curcumin preparation in patient-derived colorectal cancer organoids
- vitro+vivo, CRC, TCO1 - vitro+vivo, CRC, TCO2
cycD1/CCND1↓, cMyc↓, p‑ERK↓, CD44↓, CD133↓, LGR5↓, TumCCA↑, TumVol↓, CSCs↓,
436- CUR,    Integrated microRNA and gene expression profiling reveals the crucial miRNAs in curcumin anti‐lung cancer cell invasion
- in-vitro, Lung, A549
miR-25-5p↓, miR-330-5p↑, MAPK↓, Wnt↓,
435- CUR,    Antitumor activity of curcumin by modulation of apoptosis and autophagy in human lung cancer A549 cells through inhibiting PI3K/Akt/mTOR pathway
- in-vitro, Lung, A549
Apoptosis↑, TumAuto↑, LC3‑Ⅱ/LC3‑Ⅰ↑, Beclin-1↑, p62↓, PI3K↓, Akt↓, mTOR↓, p‑Akt↓, p‑mTOR↓,
434- CUR,    Curcumin induces apoptosis in lung cancer cells by 14-3-3 protein-mediated activation of Bad
- in-vitro, Lung, A549
14-3-3 proteins↓, p‑BAD↓, p‑Akt↓, Akt↓, cl‑Casp9↑, cl‑PARP↑,
433- CUR,    Curcumin Inhibits the Migration and Invasion of Non-Small-Cell Lung Cancer Cells Through Radiation-Induced Suppression of Epithelial-Mesenchymal Transition and Soluble E-Cadherin Expression
- in-vitro, Lung, A549
E-cadherin↓, Vim↓, Slug↓, N-cadherin↓, Snail↓, MMP9↓, EMT↓,
432- CUR,    Curcumin-Induced Global Profiling of Transcriptomes in Small Cell Lung Cancer Cells
- in-vitro, Lung, H446
Bcl-2↓, cycF↓, LOX1↓, VEGF↓, MRGPRF↓, BAX↑, Cyt‑c↑, miR-548ah-5p↑,
431- CUR,    Curcumin suppresses the stemness of non-small cell lung cancer cells via promoting the nuclear-cytoplasm translocation of TAZ
- in-vitro, Lung, A549 - in-vitro, Lung, H1299
ALDH1A1↓, CD133↓, EpCAM↓, OCT4↓, TAZ↓, Hippo↑, p‑TAZ↑,
430- CUR,    Curcumin suppresses tumor growth of gemcitabine-resistant non-small cell lung cancer by regulating lncRNA-MEG3 and PTEN signaling
- vitro+vivo, Lung, A549
PTEN↑, MEG3↑,
457- CUR,    Curcumin regulates proliferation, autophagy, and apoptosis in gastric cancer cells by affecting PI3K and P53 signaling
- in-vitro, GC, SGC-7901 - in-vitro, GC, BGC-823
TumCP↓, Apoptosis↑, TumAuto↑, P53↑, PI3K↓, P21↑, p‑Akt↓, p‑mTOR↓, Bcl-2↓, Bcl-xL↓, LC3I↓, BAX↑, Beclin-1↑, cl‑Casp3↑, cl‑PARP↑, LC3II↑, ATG3↑, ATG5↑,
438- CUR,    Curcumin Reduces Colorectal Cancer Cell Proliferation and Migration and Slows In Vivo Growth of Liver Metastases in Rats
- vitro+vivo, CRC, CC531
TumCP↓, TumVol↓, Albumin↑, ALP↑, AST↑, ALAT↑, cholinesterase↓,
417- CUR,    Curcumin inhibits the growth of triple‐negative breast cancer cells by silencing EZH2 and restoring DLC1 expression
- vitro+vivo, BC, MCF-7 - vitro+vivo, BC, MDA-MB-231 - vitro+vivo, BC, MDA-MB-468
EZH2↓, DLC1↑, cycA1/CCNA1↓, CDK1↓, Bcl-2↓, Casp9↑, DLC1↑,
420- CUR,    Anti-metastasis activity of curcumin against breast cancer via the inhibition of stem cell-like properties and EMT
- in-vitro, BC, MCF-7 - in-vitro, BC, MDA-MB-231
Vim↓, Fibronectin↓, β-catenin/ZEB1↓, E-cadherin↓, CD44↑, CD24↓, OCT4↓, Nanog↓, SOX2↓,
422- CUR,    Curcumin induces re-expression of BRCA1 and suppression of γ synuclein by modulating DNA promoter methylation in breast cancer cell lines
- in-vitro, BC, HCC-38 - in-vitro, BC, T47D
BRCA1↑, TET1↑, DNMT3A↑, DNMT1↓, SNCG↓, miR-29b↓, miR-29b↑,
423- CUR,    Inhibition of TLR4/TRIF/IRF3 Signaling Pathway by Curcumin in Breast Cancer Cells
- in-vitro, BC, MCF-7 - in-vitro, BC, MDA-MB-231
TLR4↓, IRF3↓, IFN-γ↓, TRIF↓,
424- CUR,    Curcumin inhibits autocrine growth hormone-mediated invasion and metastasis by targeting NF-κB signaling and polyamine metabolism in breast cancer cells
- in-vitro, BC, MCF-7 - in-vitro, BC, MDA-MB-231
Src↓, p‑STAT1↓, p‑Akt↓, p‑p44↓, p‑p42↓, RAS↓, Raf↓, Vim↓, β-catenin/ZEB1↓, P53↓, Bcl-2↓, Mcl-1↓, PIAS-3↑, SOCS-3↑, SOCS1↑, ROS↑, NF-kB↓, PAO↑, SSAT↑, P21↑, Bak↑,
425- CUR,    Curcumin inhibits proliferation and promotes apoptosis of breast cancer cells
- in-vitro, BC, T47D - in-vitro, BC, MCF-7 - in-vitro, BC, MDA-MB-231 - in-vitro, BC, MDA-MB-468
CDC25↓, cDC2↓, P21↑, p‑Akt↓, p‑mTOR↓, Bcl-2↓, BAX↑, Casp3↑,
426- CUR,    Use of cancer chemopreventive phytochemicals as antineoplastic agents
- in-vitro, BC, MDA-MB-231 - in-vitro, BC, CAL51
Bcl-2↓, ROS↑, BAX↑, RAD51↑, γH2AX↑,
427- CUR,    Curcumin suppresses the malignancy of non-small cell lung cancer by modulating the circ-PRKCA/miR-384/ITGB1 pathway
- in-vitro, Lung, H1299 - in-vitro, Lung, H460 - vitro+vivo, Lung, A549
ITGB1↓, circ-PRKCA↓, miR-384↑,
429- CUR,    TAp63α Is Involved in Tobacco Smoke-Induced Lung Cancer EMT and the Anti-cancer Activity of Curcumin via miR-19 Transcriptional Suppression
- in-vitro, Lung, H1299 - in-vitro, Lung, A549
TAp63α↑, E-cadherin↑, ZO-1↑, Vim↓, N-cadherin↓, miR-19b↓,
447- CUR,  OXA,    Curcumin reverses oxaliplatin resistance in human colorectal cancer via regulation of TGF-β/Smad2/3 signaling pathway
- vitro+vivo, CRC, HCT116
p‑p65↓, Bcl-2↓, Casp3↑, EMT↓, p‑SMAD2↓, p‑SMAD3↓, N-cadherin↓, TGF-β↓, E-cadherin↑, TumVol↓, TumCMig↓,
456- CUR,    Curcumin Promoted miR-34a Expression and Suppressed Proliferation of Gastric Cancer Cells
- vitro+vivo, GC, SGC-7901
miR-34a↑, TumCP↓, TumCMig↓, TumCI↓, TumCCA↑, Bcl-2↓, CDK4/6↓, cycD1/CCND1↓,
455- CUR,    Curcumin Affects Gastric Cancer Cell Migration, Invasion and Cytoskeletal Remodeling Through Gli1-β-Catenin
- in-vitro, GC, SGC-7901
Shh↓, Gli1↓, FOXM1↓, β-catenin/ZEB1↓, TumCMig↓, Apoptosis↑, TumCCA↑, Wnt↓, EMT↓, E-cadherin↑, Vim↓,
454- CUR,    Curcumin-Induced DNA Demethylation in Human Gastric Cancer Cells Is Mediated by the DNA-Damage Response Pathway
- in-vitro, GC, MGC803
TumCMig↓, TumCP↓, ROS↑, mtDam↑, DNAdam↑, Apoptosis↑, ATR↑, P21↑, p‑P53↑, GADD45A↑, p‑γH2AX↑,
453- CUR,    Cellular uptake and apoptotic properties of gemini curcumin in gastric cancer cells
- in-vitro, GC, AGS
Bcl-2↓, survivin↓, BAX↑, TumCCA↑,
452- CUR,    Curcumin downregulates the PI3K-AKT-mTOR pathway and inhibits growth and progression in head and neck cancer cells
- vitro+vivo, HNSCC, SCC9 - vitro+vivo, HNSCC, FaDu - vitro+vivo, HNSCC, HaCaT
TumCCA↑, PI3k/Akt/mTOR↓, Casp3↑, EGFR↓, EGF↑, PRKCG↑, p‑Akt↓, p‑mTOR↓, RPS6KA1↓, EIF4E↓, proCasp3↓,
451- CUR,    The effect of Curcumin on multi-level immune checkpoint blockade and T cell dysfunction in head and neck cancer
- vitro+vivo, HNSCC, SCC15 - vitro+vivo, HNSCC, SNU1076 - vitro+vivo, HNSCC, SNU1041
TumCMig↓, TumCG↓, PD-L1↓, PD-L2↓, Galectin-9↓, EMT↓, T-Cell↑, TILs↑, PD-1↓, TIM-3↓, CD4+↓, CD25+↓, FoxP3+↓, E-cadherin↑, CD8+↑, IFN-γ↑,
450- CUR,    Curcumin may be a potential adjuvant treatment drug for colon cancer by targeting CD44
- in-vitro, CRC, HCT116 - in-vitro, CRC, HCT8
TumCP↓, TumCMig↓, CD44↓, CSCs↓,
449- CUR,    Curcumin Suppresses the Colon Cancer Proliferation by Inhibiting Wnt/β-Catenin Pathways via miR-130a
- vitro+vivo, CRC, SW480
TumCP↓, β-catenin/ZEB1↓, TCF↓, miR-21↓, NKD2↑, miR-130a↓,
448- CUR,    Heat shock protein 27 influences the anti-cancer effect of curcumin in colon cancer cells through ROS production and autophagy activation
- in-vitro, CRC, HT-29
Apoptosis↑, TumCCA↑, p‑Akt↓, Akt↓, Bcl-2↓, p‑BAD↓, BAD↑, cl‑PARP↑, ROS↑, HSP27↑, Beclin-1↑, p62↑, GPx1↓, GPx4↓,
446- CUR,    The Influence of Curcumin on the Downregulation of MYC, Insulin and IGF-1 Receptors: A Possible Mechanism Underlying the Anti-Growth and Anti-Migration in Chemoresistant Colorectal Cancer Cells
- in-vitro, CRC, SW480
IR↓, IGF-1↓, Myc↓, TumCMig↓, TumCP↓,
445- CUR,    Curcumin Regulates the Progression of Colorectal Cancer via LncRNA NBR2/AMPK Pathway
- in-vitro, CRC, HCT116 - in-vitro, CRC, HCT8 - in-vitro, CRC, SW480 - in-vitro, CRC, SW-620
p‑AMPK↑, p‑ACC-α↑, NBR2↑, p‑S6K↓, mTOR↓,
444- CUR,  Cisplatin,    LncRNA KCNQ1OT1 is a key factor in the reversal effect of curcumin on cisplatin resistance in the colorectal cancer cells
- vitro+vivo, CRC, HCT8
TumVol↓, Apoptosis↑, Bcl-2↓, Cyt‑c↑, BAX↑, cl‑Casp3↑, cl‑PARP1↑, miR-497↑, KCNQ1OT1↓,
443- CUR,    Reduced Caudal Type Homeobox 2 (CDX2) Promoter Methylation Is Associated with Curcumin’s Suppressive Effects on Epithelial-Mesenchymal Transition in Colorectal Cancer Cells
- in-vitro, CRC, SW480
DNMT1↓, DNMT3A↓, N-cadherin↓, Vim↓, Wnt↓, Snail↓, Twist↓, β-catenin/ZEB1↓, E-cadherin↑, EMT↓, CDX2↓,
442- CUR,  5-FU,    Curcumin may reverse 5-fluorouracil resistance on colonic cancer cells by regulating TET1-NKD-Wnt signal pathway to inhibit the EMT progress
- in-vitro, CRC, HCT116
Apoptosis↑, TumCP↓, TumCCA↑, TET1↑, NKD2↑, Wnt↓, EMT↓, Vim↑, E-cadherin↓, β-catenin/ZEB1↓, TCF↓, AXIN1↓,
441- CUR,    Curcumin Regulates ERCC1 Expression and Enhances Oxaliplatin Sensitivity in Resistant Colorectal Cancer Cells through Its Effects on miR-409-3p
- in-vitro, CRC, HCT116
ERCC1↓, Bcl-2↓, GSTP1/GSTπ↓, MRP↓, P-gp↓, miR-409-3p↑, survivin↓,
440- CUR,    Curcumin Reverses NNMT-Induced 5-Fluorouracil Resistance via Increasing ROS and Cell Cycle Arrest in Colorectal Cancer Cells
- vitro+vivo, CRC, SW480 - vitro+vivo, CRC, HT-29
NNMT↓, p‑STAT3↓, TumCP↓, TumCCA↑, ROS↑,
439- CUR,    Curcumin suppresses LGR5(+) colorectal cancer stem cells by inducing autophagy and via repressing TFAP2A-mediated ECM pathway
- in-vitro, CRC, LGR5
Apoptosis↑, TumAuto↑, GP1BB↓, COL9A3↓, COMP↓, AGRN↓, ITGB4↓, LAMA5↓, COL2A1↓, ITGB6↓, LGR5↓, TFAP2A↓, ECM/TCF↓,
1108- CUR,    Curcumin: a potent agent to reverse epithelial-to-mesenchymal transition
- Review, NA, NA
EMT↓,
1006- CUR,    The effect of Curcuma longa extract and its active component (curcumin) on gene expression profiles of lipid metabolism pathway in liver cancer cell line (HepG2)
- in-vitro, Liver, HepG2
TumCP↓, PGC1A↑, CPT1A↑, ACOX1↑, SCD1↓, SREBF2↓, DGAT1↓,
1034- CUR,  immuno,    Enhanced anti‐tumor effects of the PD‐1 blockade combined with a highly absorptive form of curcumin targeting STAT3
- in-vivo, NA, NA
DCells↑, T-Cell↑,
170- CUR,    Curcumin sensitizes TRAIL-resistant xenografts: molecular mechanisms of apoptosis, metastasis and angiogenesis
- vitro+vivo, Pca, PC3
TRAILR↑, BAX↑, P21↑, p27↑, NF-kB↓, cycD1/CCND1↓, VEGF↓, uPA↓, MMP2↓, MMP9↓, Bcl-2↓, Bcl-xL↓,
181- CUR,    The effects of curcumin on the invasiveness of prostate cancer in vitro and in vivo
- vitro+vivo, Pca, DU145
MMP2↓, MMP9↓, TumCP↓, TumCI↓,
182- CUR,  RES,  GI,    Chemopreventive anti-inflammatory activities of curcumin and other phytochemicals mediated by MAP kinase phosphatase-5 in prostate cells
- in-vitro, Pca, DU145 - in-vitro, Pca, PC3 - in-vitro, Pca, LNCaP - in-vitro, Pca, LAPC-4
p38↓, MKP5↑, TNF-α↓, COX2↓, NF-kB↓,
183- CUR,    Curcumin down-regulates AR gene expression and activation in prostate cancer cell lines
- in-vitro, Pca, LNCaP - in-vitro, Pca, PC3
AR↓, AP-1↓, NF-kB↓, CBP↓,
169- CUR,    Curcumin inhibits the expression of vascular endothelial growth factor and androgen-independent prostate cancer cell line PC-3 in vitro
- in-vitro, Pca, PC3
VEGF↓,
168- CUR,    Curcumin inhibits Akt/mammalian target of rapamycin signaling through protein phosphatase-dependent mechanism
- in-vitro, Pca, PC3
Akt↓, mTOR↓, AMPK↑, TAp63α↑, TumCP↓,
2312- CUR,    Dual Role of Reactive Oxygen Species and their Application in Cancer Therapy
- Review, Var, NA
ROS↑, PKM2↓,
2304- CUR,    Curcumin decreases Warburg effect in cancer cells by down-regulating pyruvate kinase M2 via mTOR-HIF1α inhibition
- in-vitro, Lung, H1299 - in-vitro, BC, MCF-7 - in-vitro, Cerv, HeLa - in-vitro, Pca, PC3 - in-vitro, Nor, HEK293
Glycolysis↓, GlucoseCon↓, lactateProd↓, PKM2↓, mTOR↓, Hif1a↓, selectivity↑, Dose↝, tumCV↓,
2305- CUR,    Mitochondrial targeting nano-curcumin for attenuation on PKM2 and FASN
- in-vitro, BC, MCF-7
BioAv↑, PKM2↓, FASN↓, Glycolysis↓,

Showing Research Papers: 2101 to 2150 of 5820
Prev Page 43 of 117 Next

* indicates research on normal cells as opposed to diseased cells
Total Research Paper Matches: 5820

Pathway results for Effect on Cancer / Diseased Cells:


Redox & Oxidative Stress ⓘ

Ferroptosis↑, 1,   GPx↓, 1,   GPx1↓, 1,   GPx4↓, 2,   GSH↓, 1,   GSTP1/GSTπ↓, 1,   HO-1↑, 1,   Iron↑, 2,   lipid-P↑, 1,   MDA↑, 2,   NFE2L2↑, 1,   NRF2↑, 1,   PAO↑, 1,   ROS↑, 8,  

Metal & Cofactor Biology ⓘ

FTH1↑, 1,   FTL↑, 1,  

Mitochondria & Bioenergetics ⓘ

CDC25↓, 1,   EGF↑, 1,   MKP5↑, 1,   mtDam↑, 1,   p‑p42↓, 1,   Raf↓, 1,  

Core Metabolism/Glycolysis ⓘ

p‑ACC-α↑, 1,   ACOX1↑, 1,   ALAT↑, 1,   AMPK↑, 1,   p‑AMPK↑, 1,   cMyc↓, 1,   CPT1A↑, 1,   DGAT1↓, 1,   ERCC1↓, 1,   FASN↓, 1,   GlucoseCon↓, 1,   Glycolysis↓, 2,   IR↓, 1,   lactateProd↓, 1,   NNMT↓, 1,   PGC1A↑, 1,   PI3k/Akt/mTOR↓, 1,   PKM2↓, 3,   p‑S6K↓, 1,   SCD1↓, 1,   SREBF2↓, 1,   SSAT↑, 1,  

Cell Death ⓘ

14-3-3 proteins↓, 1,   Akt↓, 4,   p‑Akt↓, 7,   Apoptosis↑, 8,   BAD↑, 1,   p‑BAD↓, 2,   Bak↑, 1,   BAX↑, 7,   Bcl-2↓, 13,   Bcl-xL↓, 2,   Casp3↑, 3,   cl‑Casp3↑, 2,   proCasp3↓, 1,   Casp9↑, 1,   cl‑Casp9↑, 1,   CBP↓, 1,   Cyt‑c↑, 2,   Ferroptosis↑, 1,   Hippo↑, 1,   MAPK↓, 1,   Mcl-1↓, 1,   MEG3↑, 1,   miR-497↑, 1,   miR-548ah-5p↑, 1,   Myc↓, 1,   p27↑, 1,   p38↓, 1,   survivin↓, 2,   TRAILR↑, 1,  

Kinase & Signal Transduction ⓘ

miR-25-5p↓, 1,  

Transcription & Epigenetics ⓘ

COMP↓, 1,   EZH2↓, 1,   KCNQ1OT1↓, 1,   miR-21↓, 1,   miR-409-3p↑, 1,   tumCV↓, 1,   USF1↑, 1,  

Protein Folding & ER Stress ⓘ

ATFs↑, 1,   CHOP↑, 1,   HSP27↑, 1,   HSP70/HSPA5↑, 1,  

Autophagy & Lysosomes ⓘ

ATG3↑, 1,   ATG5↑, 1,   Beclin-1↑, 3,   LC3‑Ⅱ/LC3‑Ⅰ↑, 1,   LC3I↓, 1,   LC3II↑, 1,   p62↓, 1,   p62↑, 1,   TumAuto↑, 3,  

DNA Damage & Repair ⓘ

ATR↑, 1,   BRCA1↑, 1,   DNAdam↑, 1,   DNMT1↓, 2,   DNMT3A↓, 1,   DNMT3A↑, 1,   GADD45A↑, 1,   NBR2↑, 1,   P53↓, 1,   P53↑, 1,   p‑P53↑, 1,   cl‑PARP↑, 3,   cl‑PARP1↑, 1,   RAD51↑, 1,   γH2AX↑, 1,   p‑γH2AX↑, 1,  

Cell Cycle & Senescence ⓘ

CDK1↓, 1,   cycA1/CCNA1↓, 1,   cycD1/CCND1↓, 3,   cycF↓, 1,   P21↑, 5,   TAp63α↑, 2,   TFAP2A↓, 1,   TumCCA↑, 8,  

Proliferation, Differentiation & Cell State ⓘ

ALDH1A1↓, 1,   AXIN1↓, 1,   CD133↓, 2,   CD24↓, 1,   CD44↓, 2,   CD44↑, 1,   cDC2↓, 1,   CDX2↓, 1,   CSCs↓, 2,   EIF4E↓, 1,   EMT↓, 7,   EpCAM↓, 1,   p‑ERK↓, 1,   FOXM1↓, 1,   Gli1↓, 1,   IGF-1↓, 1,   LGR5↓, 2,   miR-330-5p↑, 1,   miR-34a↑, 1,   mTOR↓, 4,   p‑mTOR↓, 4,   Nanog↓, 1,   NKD2↑, 2,   OCT4↓, 2,   PI3K↓, 2,   PIAS-3↑, 1,   PRKCG↑, 1,   PTEN↑, 1,   RAS↓, 1,   RPS6KA1↓, 1,   Shh↓, 1,   SOX2↓, 1,   Src↓, 1,   p‑STAT1↓, 1,   p‑STAT3↓, 1,   TAZ↓, 1,   p‑TAZ↑, 1,   TCF↓, 2,   TumCG↓, 1,   Wnt↓, 4,  

Migration ⓘ

AGRN↓, 1,   AP-1↓, 1,   BACH1↑, 1,   CDK4/6↓, 1,   circ-PRKCA↓, 1,   COL2A1↓, 1,   COL9A3↓, 1,   DLC1↑, 2,   E-cadherin↓, 3,   E-cadherin↑, 5,   Fibronectin↓, 1,   Galectin-9↓, 1,   GP1BB↓, 1,   ITGB1↓, 1,   ITGB4↓, 1,   ITGB6↓, 1,   LAMA5↓, 1,   miR-130a↓, 1,   miR-19b↓, 1,   miR-29b↓, 1,   miR-29b↑, 1,   miR-384↑, 1,   MMP2↓, 2,   MMP9↓, 3,   MRGPRF↓, 1,   N-cadherin↓, 4,   p‑p44↓, 1,   Slug↓, 1,   p‑SMAD2↓, 1,   p‑SMAD3↓, 1,   Snail↓, 2,   TET1↑, 2,   TGF-β↓, 1,   TumCI↓, 2,   TumCMig↓, 7,   TumCP↓, 12,   Twist↓, 1,   uPA↓, 1,   Vim↓, 6,   Vim↑, 1,   ZO-1↑, 1,   β-catenin/ZEB1↓, 6,  

Angiogenesis & Vasculature ⓘ

ECM/TCF↓, 1,   EGFR↓, 1,   Hif1a↓, 1,   LOX1↓, 1,   REL↑, 1,   VEGF↓, 3,  

Barriers & Transport ⓘ

MRP↓, 1,   P-gp↓, 1,  

Immune & Inflammatory Signaling ⓘ

CD25+↓, 1,   CD4+↓, 1,   COX2↓, 1,   DCells↑, 1,   FoxP3+↓, 1,   IFN-γ↓, 1,   IFN-γ↑, 1,   NF-kB↓, 4,   p‑p65↓, 1,   PD-1↓, 1,   PD-L1↓, 1,   PD-L2↓, 1,   SOCS-3↑, 1,   SOCS1↑, 1,   T-Cell↑, 2,   TILs↑, 1,   TLR4↓, 1,   TNF-α↓, 1,   TRIF↓, 1,  

Cellular Microenvironment ⓘ

TIM-3↓, 1,  

Synaptic & Neurotransmission ⓘ

cholinesterase↓, 1,  

Protein Aggregation ⓘ

SNCG↓, 1,  

Hormonal & Nuclear Receptors ⓘ

AR↓, 1,  

Drug Metabolism & Resistance ⓘ

BioAv↑, 1,   Dose↝, 1,   selectivity↑, 1,  

Clinical Biomarkers ⓘ

ALAT↑, 1,   Albumin↑, 1,   ALP↑, 1,   AR↓, 1,   AST↑, 1,   BRCA1↑, 1,   EGFR↓, 1,   EZH2↓, 1,   FOXM1↓, 1,   Myc↓, 1,   PD-L1↓, 1,  

Functional Outcomes ⓘ

TumVol↓, 4,  

Infection & Microbiome ⓘ

CD8+↑, 1,   IRF3↓, 1,  
Total Targets: 248

Pathway results for Effect on Normal Cells:


Total Targets: 0

Query results interpretion may depend on "conditions" listed in the research papers.
Such Conditions may include : 
  -low or high Dose
  -format for product, such as nano of lipid formations
  -different cell line effects
  -synergies with other products 
  -if effect was for normal or cancerous cells

Filter Conditions: Pro/AntiFlg:%  IllCat:%  CanType:%  Cells:%  prod#:%  Target#:%  State#:%  Dir#:%
  wNotes=0  sortOrder:rid,rpid

 

Home Page