Cancer Database Query Results

Scientific Papers found: Click to Expand⟱

AgNPs,

Immunomodulatory properties of silver nanoparticles contribute to anticancer strategy for murine fibrosarcoma

in-vivo,

fibroS,

particles was approximately 10 nm

LACA mice

TumVol↓, TNF-α↓, IL6↓, IL1β↓, *toxicity↝, TumCG↓, selectivity↑, selectivity↑, Weight↑, ROS↑, NO↑,

4432-

AgNPs,

Emerging nanostructure-based strategies for breast cancer therapy: innovations, challenges, and future directions

Review,

NA,

ROS↑, TumCP↓, Apoptosis↑,

4433-

AgNPs,

Advancements in metal and metal oxide nanoparticles for targeted cancer therapy and imaging: Mechanisms, applications, and safety concerns

in-vitro,

Liver,

HepG2

in-vitro,

Nor,

L02

selectivity↑, selectivity↓, mt-ROS↑,

4434-

AgNPs,

SSE,

Sodium Selenite Ameliorates Silver Nanoparticles Induced Vascular Endothelial Cytotoxic Injury by Antioxidative Properties and Suppressing Inflammation Through Activating the Nrf2 Signaling Pathway

vitro+vivo,

Nor,

*ROS↓, *Inflam↓, *NLRP3↓, *NF-kB↓, *NRF2↑, *HO-1↑, *toxicity↓,

4435-

AgNPs,

Gluc,

Glucose-Functionalized Silver Nanoparticles as a Potential New Therapy Agent Targeting Hormone-Resistant Prostate Cancer cells

in-vitro,

Pca,

PC3

average size of 61nm

911ug/mL

in-vitro,

Pca,

LNCaP

in-vitro,

Pca,

DU145

1579ug/mL

selectivity↑, ROS↑, mtDam↑, TumCCA↑, TumCP↓, Apoptosis↑, MMP↓,

4436-

AgNPs,

Silver Nanoparticles (AgNPs) as Enhancers of Everolimus and Radiotherapy Sensitivity on Clear Cell Renal Cell Carcinoma

in-vitro,

Kidney,

786-O

61 ± 10 nm

AgNP doses ranging from 500 to 3000 µg/mL for 24 h

ROS↑, MMP↑, TumCCA↑, TumCP↓, Apoptosis↑, RadioS↑,

4437-

AgNPs,

Green Fabrication of silver nanoparticles by leaf extract of Byttneria Herbacea Roxb and their promising therapeutic applications and its interesting insightful observations in oral cancer

in-vitro,

Oral,

BH-AgNPs are almost spherical in nature with an average size range from of 2 nm to 12 nm.

TumCP↓,

4438-

AgNPs,

ART/DHA,

Biogenic synthesis of AgNPs using Artemisia oliveriana extract and their biological activities for an effective treatment of lung cancer

in-vitro,

Lung,

A549

EPR↑, BAX↑, Bcl-2↑, Casp3↑, Casp9↑, DNAdam↑, TumCCA↑, Apoptosis↑,

4439-

AgNPs,

Anticancer Potential of Green Synthesized Silver Nanoparticles Using Extract of Nepeta deflersiana against Human Cervical Cancer Cells (HeLA)

in-vitro,

Cerv,

HeLa

33 nm

ROS↑, lipid-P↑, MMP↓, GSH↓, TumCCA↑, Apoptosis↑, Necroptosis↑, TumCD↑, Dose↝,

4447-

AgNPs,

Anti-inflammatory action of silver nanoparticles in vivo: systematic review and meta-analysis

Review,

Nor,

*Inflam↓, *COX2↓, *ROS↓, *Dose↝, *eff↑, *toxicity↓, *IL4↑, *IL5↑, *IL10↑, *IL1↓, *IL6↓, *TNF-α↓, *NF-kB↓, *MDA↓, *GSH↑,

4364-

AgNPs,

Selective cytotoxicity of green synthesized silver nanoparticles against the MCF-7 tumor cell line and their enhanced antioxidant and antimicrobial properties

in-vitro,

BC,

MCF-7

31.4 nm with a Zeta potential of −33.8 mV,

TumCD↑, selectivity↑, *antiOx↑, *Inflam↓, AntiTum↑, ROS↑,

4381-

AgNPs,

Oxidative stress-dependent toxicity of silver nanoparticles in human hepatoma cells

in-vitro,

Liver,

HepG2

 human hepatoma cells.

eff↓, ROS↑, other↑,

4380-

AgNPs,

Silver nanoparticles induce toxicity in A549 cells via ROS-dependent and ROS-independent pathways

in-vitro,

Lung,

A549

ROS↑, tumCV↓, MMP↓, TumCCA↑, PCNA↓, eff↓,

4379-

AgNPs,

Exposure to silver nanoparticles induces size- and dose-dependent oxidative stress and cytotoxicity in human colon carcinoma cells

in-vitro,

CRC,

LoVo

eff↑, TumCD↑, ROS↑, Bacteria↓,

4378-

AgNPs,

Exploring silver nanoparticles for cancer therapy and diagnosis

Review,

Var,

AntiTum↑, ROS↑, eff↑, RadioS↑,

4377-

AgNPs,

Interaction between silver nanoparticles of 20 nm (AgNP20 ) and human neutrophils: induction of apoptosis and inhibition of de novo protein synthesis by AgNP20 aggregates

in-vitro,

NA,

human neutrophils (white blood cell) ie transportation

eff↑, Apoptosis↑,

4376-

AgNPs,

Interaction of multi-functional silver nanoparticles with living cells

in-vitro,

Nor,

L929

in-vitro,

Lung,

A549

eff↑, selectivity↑,

4375-

AgNPs,

The cellular uptake and cytotoxic effect of silver nanoparticles on chronic myeloid leukemia cells

in-vitro,

AML,

K562

eff↑, ROS↑, Apoptosis↑, eff↓,

4374-

AgNPs,

Enhancing antitumor activity of silver nanoparticles by modification with cell-penetrating peptides

in-vitro,

BC,

MCF-7

eff↑, TumCD↑,

4373-

AgNPs,

In vitro toxicity of silver nanoparticles at noncytotoxic doses to HepG2 human hepatoma cells

in-vitro,

Liver,

HepG2

TumCD↑,

4372-

AgNPs,

Negligible particle-specific toxicity mechanism of silver nanoparticles: the role of Ag+ ion release in the cytosol

in-vitro,

Cerv,

HeLa

in-vitro,

Lung,

A549

TumCD↑,

4371-

AgNPs,

Effects of Green Silver Nanoparticles on Apoptosis and Oxidative Stress in Normal and Cancerous Human Hepatic Cells in vitro

in-vitro,

Liver,

HUH7

20−50 nm

eco-friendly approach silver nanoparticles (AgNPs) using root extracts of Beta vulgaris L.

ROS↑, selectivity↑, DNAdam↑, Apoptosis↑, GSH↓, lipid-P↑, MMP↓, DNAdam↑,

4370-

AgNPs,

Effect of silver nanoparticles in the induction of apoptosis on human hepatocellular carcinoma (HepG2) cell line

in-vitro,

Liver,

HepG2

 30.71 nm

75 μg/mL

tumCV↓, ROS↑, Apoptosis↑,

4369-

AgNPs,

Silver nanoparticles induce p53-mediated apoptosis in human bronchial epithelial (BEAS-2B) cells

in-vitro,

Nor,

BEAS-2B

*ROS↑,

4368-

AgNPs,

Silver nanoparticles crossing through and distribution in the blood-brain barrier in vitro

NA,

Nor,

*BBB↑,

4367-

AgNPs,

Effects of Prolonged Silver Nanoparticle Exposure on the Contextual Cognition and Behavior of Mammals

in-vivo,

Nor,

Eighty C57Вl/6 eight-week-old male mice

*other↝,

4366-

AgNPs,

Gut Dysbiosis and Neurobehavioral Alterations in Rats Exposed to Silver Nanoparticles

in-vivo,

Nor,

 Sprague-Dawley male rats for two weeks

*GutMicro↝,

4365-

AgNPs,

Biomedical Applications of Silver Nanoparticles: An Up-to-Date Overview

Review,

Var,

ROS↑, *toxicity↓, *Bacteria↓, *Inf↓, *Diff↑, *eff↑, RadioS↑, selectivity↑,

4383-

AgNPs,

Exploring the Potentials of Silver Nanoparticles in Overcoming Cisplatin Resistance in Lung Adenocarcinoma: Insights from Proteomic and Xenograft Mice Studies

in-vitro,

Lung,

A549

AgNPs was 23.45 nm, with zeta potentials lying on −20.33 mV.

in-vivo,

Lung,

A549

A549 and A549/DDP-bearing mice

Apoptosis↑, VEGF↓, P53↓, TumCCA↑, ROS↑, AntiTum↑, eff↑, ATP↓, eff↑, CTR1↑,

4661-

AgNPs,

Silver nanoparticles induces apoptosis of cancer stem cells in head and neck cancer

in-vitro,

HNSCC,

TumCD↑, CSCs↝,

4552-

AgNPs,

ART/DHA,

Green synthesis of silver nanoparticles using Artemisia turcomanica leaf extract and the study of anti-cancer effect and apoptosis induction on gastric cancer cell line (AGS)

in-vitro,

GC,

AGS

AntiCan↑, Apoptosis↑, eff↑,

4564-

AgNPs,

GoldNP,

Cu,

Chemo,

PDT

Cytotoxicity and targeted drug delivery of green synthesized metallic nanoparticles against oral Cancer: A review

Review,

Var,

ROS↑, DNAdam↑, TumCCA↑, eff↑, Apoptosis↑, eff↓, ChemoSen↑,

4563-

AgNPs,

Rad,

Silver nanoparticles enhance neutron radiation sensitivity in cancer cells: An in vitro study

in-vitro,

BC,

MCF-7

in-vitro,

Ovarian,

SKOV3

in-vitro,

GBM,

U87MG

in-vitro,

Melanoma,

A431

RadioS↑, ROS↑, TumCCA↑, Apoptosis↑, ER Stress↑,

4562-

AgNPs,

VitC,

Eco-friendly Synthesis of Silver Nanoparticles using Ascorbic Acid and its Optical Characterization

Study,

NA,

*other↑, *other↝,

4561-

AgNPs,

VitC,

Cellular Effects Nanosilver on Cancer and Non-cancer Cells: Potential Environmental and Human Health Impacts

in-vitro,

CRC,

HCT116

in-vitro,

Nor,

HEK293

NRF2↑, TumCCA↑, ROS↑, selectivity↑, *AntiViral↑, *toxicity↝, ETC↓, MMP↓, DNAdam↑, Apoptosis↑, lipid-P↑, other↝, UPR↑, *GRP78/BiP↑, *p‑PERK↑, *cl‑eIF2α↑, *CHOP↑, *JNK↑, Hif1a↓, AntiCan↑, *toxicity↓, eff↑,

4560-

AgNPs,

Exploiting antidiabetic activity of silver nanoparticles synthesized using Punica granatum leaves and anticancer potential against human liver cancer cells (HepG2)

in-vitro,

Liver,

HepG2

in-vitro,

Diabetic,

AntiCan↑, Dose↝, *antiOx↑, *AntiDiabetic↑, *Bacteria↓,

4559-

AgNPs,

Anticancer activity of biogenerated silver nanoparticles: an integrated proteomic investigation

in-vitro,

BC,

SkBr3

IC50 value of 5 μg/ml

in-vitro,

CRC,

HT-29

in-vitro,

CRC,

HCT116

in-vitro,

Colon,

Caco-2

MMP2↓, MMP9↓, ROS↑, TumAuto↑, Apoptosis↑, ER Stress↑,

4558-

AgNPs,

Role of Oxidative and Nitro-Oxidative Damage in Silver Nanoparticles Cytotoxic Effect against Human Pancreatic Ductal Adenocarcinoma Cells

in-vitro,

PC,

PANC1

3.19 ug/mL

ROS↑, selectivity↑, NO↑, SOD↓, GPx4↓, Catalase↓, TumCCA↑, MMP↓,

4557-

AgNPs,

The apoptotic effect of nanosilver is mediated by a ROS- and JNK-dependent mechanism involving the mitochondrial pathway in NIH3T3 cells

in-vitro,

NA,

NIH-3T3

in-vitro,

CRC,

HCT116

Cyt‑c↑, ROS↑, JNK↑,

4556-

AgNPs,

Biofilm Impeding AgNPs Target Skin Carcinoma by Inducing Mitochondrial Membrane Depolarization Mediated through ROS Production

in-vitro,

Melanoma,

A431

MMP↓, ROS↑, *toxicity↓, Bacteria↓,

4555-

AgNPs,

Silver nanoparticles from Dendropanax morbifera Léveille inhibit cell migration, induce apoptosis, and increase generation of reactive oxygen species in A549 lung cancer cells

in-vitro,

Lung,

A549

in-vitro,

Liver,

HepG2

*Bacteria↓, tumCV↓, selectivity↑, ROS↑, Apoptosis↑, TumCMig↓, AntiCan↑,

4554-

AgNPs,

Involvement of telomerase activity inhibition and telomere dysfunction in silver nanoparticles anticancer effects

in-vitro,

Cerv,

HeLa

Telomerase↓, eff↝,

4553-

AgNPs,

Cytotoxicity induced by engineered silver nanocrystallites is dependent on surface coatings and cell types

in-vitro,

Nor,

RAW264.7

*Wound Healing↑, *eff↝, *toxicity↝,

4539-

AgNPs,

VitC,

Citrate,

Investigating the Anti-cancer Potential of Silver Nanoparticles Synthesized by Chemical Reduction of AgNO3 Using Trisodium Citrate and Ascorbic Acid

in-vitro,

Nor,

L929

average diameter of 30 nm

in-vitro,

Ovarian,

SKOV3

AntiCan↑,

4551-

AgNPs,

Fenb,

Ångstrom-Scale Silver Particles as a Promising Agent for Low-Toxicity Broad-Spectrum Potent Anticancer Therapy

in-vivo,

Lung,

mice

eff↑, eff↑, Apoptosis↑, selectivity↓, TumCG↓,

4550-

AgNPs,

The Effect of Charge at the Surface of Silver Nanoparticles on Antimicrobial Activity against Gram-Positive and Gram-Negative Bacteria: A Preliminary Study

Study,

Nor,

*Bacteria↓,

4549-

AgNPs,

Silver nanoparticles: Synthesis, medical applications and biosafety

Review,

Var,

Review,

Diabetic,

ROS↑, eff↑, other↝, DNAdam↑, EPR↑, eff↑, eff↑, TumMeta↓, angioG↓, *Bacteria↓, *eff↑, *AntiViral↑, *AntiFungal↑, eff↑, eff↑, TumCP↓, tumCV↓, P53↝, HIF-1↓, TumCCA↑, lipid-P↑, ATP↓, Cyt‑c↑, MMPs↓, PI3K↓, Akt↓, *Wound Healing↑, *Inflam↓, *Bone Healing↑, *glucose↓, *AntiDiabetic↑, *BBB↑,

4548-

AgNPs,

Chit,

Synergistic combination of antioxidants, silver nanoparticles and chitosan in a nanoparticle based formulation: Characterization and cytotoxic effect on MCF-7 breast cancer cell lines

in-vitro,

BC,

MCF-7

AntiCan↑, EPR↑, pH↝,

4547-

AgNPs,

GoldNP,

VitC,

Exploration of Biocompatible Ascorbic Acid Reduced and Stabilized Gold Nanoparticles, as Sensitive and Selective Detection Nanoplatform for Silver Ion in Solution

Study,

NA,

*eff↑,

4546-

AgNPs,

Chapter 2 - Silver nanoparticles in cancer therapy

Study,

Var,

AntiTum↑, Apoptosis↑,

Showing Research Papers: 201 to 250 of 5729
Prev Page 5 of 115 Next

* indicates research on normal cells as opposed to diseased cells
Total Research Paper Matches: 5729

Pathway results for Effect on Cancer / Diseased Cells:

Infection & Microbiome ⓘ

Bacteria↓, 2,
Total Targets: 69

Pathway results for Effect on Normal Cells:

Redox & Oxidative Stress ⓘ

antiOx↑, 2, GSH↑, 1, HO-1↑, 1, MDA↓, 1, NRF2↑, 1, ROS↓, 2, ROS↑, 1,

Core Metabolism/Glycolysis ⓘ

glucose↓, 1,

Cell Death ⓘ

JNK↑, 1,

Transcription & Epigenetics ⓘ

other↑, 1, other↝, 2,

Protein Folding & ER Stress ⓘ

CHOP↑, 1, cl‑eIF2α↑, 1, GRP78/BiP↑, 1, p‑PERK↑, 1,

Proliferation, Differentiation & Cell State ⓘ

Diff↑, 1,

Barriers & Transport ⓘ

BBB↑, 2,

Immune & Inflammatory Signaling ⓘ

COX2↓, 1, IL1↓, 1, IL10↑, 1, IL4↑, 1, IL5↑, 1, IL6↓, 1, Inflam↓, 4, NF-kB↓, 2, TNF-α↓, 1,

Protein Aggregation ⓘ

NLRP3↓, 1,

Drug Metabolism & Resistance ⓘ

Dose↝, 1, eff↑, 4, eff↝, 1,

Clinical Biomarkers ⓘ

GutMicro↝, 1, IL6↓, 1,

Functional Outcomes ⓘ

AntiDiabetic↑, 2, Bone Healing↑, 1, toxicity↓, 5, toxicity↝, 3, Wound Healing↑, 2,

Infection & Microbiome ⓘ

AntiFungal↑, 1, AntiViral↑, 2, Bacteria↓, 5, Inf↓, 1,
Total Targets: 41

Query results interpretion may depend on "conditions" listed in the research papers.
Such Conditions may include : 
  -low or high Dose
  -format for product, such as nano of lipid formations
  -different cell line effects
  -synergies with other products 
  -if effect was for normal or cancerous cells

Filter Conditions: Pro/AntiFlg:%  IllCat:%  CanType:%  Cells:%  prod#:%  Target#:%  State#:%  Dir#:%
  wNotes=0  sortOrder:rid,rpid

Cancer Database Query Results

Pathway results for Effect on Cancer / Diseased Cells:

Redox & Oxidative Stress ⓘ

Mitochondria & Bioenergetics ⓘ

Cell Death ⓘ

Transcription & Epigenetics ⓘ

Protein Folding & ER Stress ⓘ

Autophagy & Lysosomes ⓘ

DNA Damage & Repair ⓘ

Cell Cycle & Senescence ⓘ

Proliferation, Differentiation & Cell State ⓘ

Migration ⓘ

Angiogenesis & Vasculature ⓘ

Barriers & Transport ⓘ

Immune & Inflammatory Signaling ⓘ

Cellular Microenvironment ⓘ

Drug Metabolism & Resistance ⓘ

Clinical Biomarkers ⓘ

Functional Outcomes ⓘ

Infection & Microbiome ⓘ

Pathway results for Effect on Normal Cells:

Redox & Oxidative Stress ⓘ

Core Metabolism/Glycolysis ⓘ

Cell Death ⓘ

Transcription & Epigenetics ⓘ

Protein Folding & ER Stress ⓘ

Proliferation, Differentiation & Cell State ⓘ

Barriers & Transport ⓘ

Immune & Inflammatory Signaling ⓘ

Protein Aggregation ⓘ

Drug Metabolism & Resistance ⓘ

Clinical Biomarkers ⓘ

Functional Outcomes ⓘ

Infection & Microbiome ⓘ

Home Page