Cancer Database Query Results

Scientific Papers found: Click to Expand⟱
7104- GEN,    Efficacy and safety of short-term genistein intervention in patients with localized prostate cancer prior to radical prostatectomy: a randomized, placebo-controlled, double-blind Phase 2 clinical trial
- Trial, Pca, NA
Dose↝, PSA↓, *LDL↓,
7115- GeS,    A phase II study of spirogermanium as second line therapy in patients with poor prognosis lymphoma. An NCI Canada Clinical Trials Group Study
- Trial, lymphoma, NA
eff↓, toxicity↝,
7142- GI,    Phase II study of the Effects of Ginger Root Extract on Eicosanoids in Colon Mucosa in People at Normal Risk for Colorectal Cancer
- Trial, Nor, NA
COX2↓, *PGE2↓, *5-HETE↓, *12-HETE↓, *Eic↓, *AntiCan↑, *antiOx↑, *Inflam↓, 5LO↓, eff↝,
7143- GI,  Chemo,    Effect of a Standardized Ginger Root Powder Regimen on Chemotherapy-Induced Nausea and Vomiting: A Multicenter, Double-Blind, Placebo-Controlled Randomized Trial
- Trial, Var, NA
Dose↝, chemoPv↑, Nausea↓, Vomit↓, mal↓, QoL↑,
7144- GI,  Cisplatin,    A randomized, double-blind, placebo-controlled, multicenter study of a ginger extract in the management of chemotherapy-induced nausea and vomiting (CINV) in patients receiving high-dose cisplatin
- Trial, Var, NA
Dose↝, Nausea∅, Vomit∅,
7145- GI,  Chemo,    Efficacy of ginger for prophylaxis of chemotherapy-induced nausea and vomiting in breast cancer patients receiving adriamycin-cyclophosphamide regimen: a randomized, double-blind, placebo-controlled, crossover study
- Trial, BC, NA
Dose↝, toxicity∅, Nausea∅, Vomit∅,
7152- GI,    Role of Ginger in management of nausea among patients receiving chemotherapy
- Trial, Var, NA
Dose↝, Nausea↓, Vomit↓,
7135- GI,    Examination of the Pharmacokinetics of Active Ingredients of Ginger in Humans
- Trial, Nor, NA
*Dose↝, *Half-Life↝, *antiOx↑, *Inflam↓, *AntiTum↑, *Half-Life↓,
7155- GI,  BSB,    Effect of Ginger and Chamomile on Nausea and Vomiting Caused by Chemotherapy in Iranian Women with Breast Cancer
- Trial, BC, NA
Dose↝, Dose↝, Vomit↓, Nausea↓, *toxicity↓,
7158- GI,    Ginger-partitioned moxibustion in the prevention of nausea and vomiting induced by chemotherapy in lung cancer：a randomized controlled trial
- Trial, Lung, NA
Vomit↓, Nausea↓, toxicity↓, other↝,
2465- GI,    Effect of daily ginger consumption on platelet aggregation
- Trial, Nor, NA
AntiAg↝, Dose∅,
7295- Gins,    Effect of Korean Red Ginseng on Cognitive Function and Quantitative EEG in Patients with Alzheimer's Disease: A Preliminary Study
- Trial, AD, NA
*cognitive↑,
7280- Gins,    Pharmacokinetics of ginsenoside Rb1 and its metabolite compound K after oral administration of Korean Red Ginseng extract
- Trial, Nor, NA
*BioAv↑, *Half-Life↝, *eff↝,
3998- Gins,    Ginseng for Alzheimer's Disease: A Systematic Review and Meta-Analysis of Randomized Controlled Trials
- Trial, AD, NA
*other↝,
4002- Gins,    Improvement of cognitive deficit in Alzheimer's disease patients by long term treatment with korean red ginseng
- Trial, AD, NA
*cognitive↑, *other↑,
3999- Gins,    Panax ginseng enhances cognitive performance in Alzheimer disease
- Trial, NA, NA
*cognitive↑,
7303- GoldNP,  PDT,    Gold nanoshell-localized photothermal ablation of prostate tumors in a clinical pilot device study
- Trial, Pca, NA
eff↑, PSA↓,
7320- Gos,    AT-101 Enhances the Antitumor Activity of Lenalidomide in Patients with Multiple Myeloma
- Trial, Melanoma, NA
Bcl-2↓, Mcl-1↓, Apoptosis↑, eff↑, toxicity↝, ORR↑,
7317- Gos,    A phase II study of AT-101 (gossypol) in chemotherapy-sensitive recurrent extensive stage small cell lung cancer (ES-SCLC)
- Trial, Lung, NA
Bcl-2↓, Bcl-xL↓, Mcl-1↓, NOXA↑, PUMA↑, Dose↝, eff↓,
7316- Gos,  PacT,  carbop,  Chemo,    A phase I study of AT-101, a BH3 mimetic, in combination with paclitaxel and carboplatin in solid tumors
- Trial, Var, NA
Bcl-2↓, Bcl-xL↓, Mcl-1↓, Dose↝, toxicity↝,
7328- GSE,    Effects of grape seed extract beverage on blood pressure and metabolic indices in individuals with pre-hypertension: a randomised, double-blinded, two-arm, parallel, placebo-controlled trial
- Trial, Nor, NA
*Dose↝, *BP↓, *other↝, *eff↑,
7324- GSE,    A Pilot Study of a Grape Seed Procyanidin Extract for Lung Cancer Chemoprevention
- Trial, Lung, NA
BioAv↑, toxicity↝, Ki-67↓, miR-106b↓, chemoPv↑, Dose↝, miR-19b↓, PTEN↑, IGF-2R↑, p‑Akt↓, PGE2↓, PGI2↓, COX2↓, Apoptosis↑, TumCP↓, Inflam↓, cardioP↑,
7329- GSE,    Grape Seed Extract Positively Modulates Blood Pressure and Perceived Stress: A Randomized, Double-Blind, Placebo-Controlled Study in Healthy Volunteers
- Trial, Nor, NA
*Dose↝, *BP↓,
7134- GSL,    Phase I study of oral spirogermanium
- Trial, NA, NA
*Dose↝, toxicity↝, Bil∅, toxicity↝, Dose↓,
7481- H2,  Rad,    Clinical Efficacy of Hydrogen Therapy on Acute Radiation Enteritis and Inflammatory Response in Patients with Cervical Cancer Undergoing Concurrent Chemoradiation Therapy
- Trial, Var, NA
Dose↝, CRP↓, NLR↓, IL6↓, AntiTum∅, *toxicity↓, Inflam↓, radioP↑, *IBI↑, *ROS↓,
7486- H2,    Effects of hydrogen-rich water on blood uric acid in patients with hyperuricemia: A randomized placebo-controlled trial
- Trial, Nor, NA
*eff↑, *uricA↓, *toxicity↓, *antiOx↑, *Inflam↓, *Dose↝, *Dose↝, *Dose↝, *toxicity↓, *Dose↓, *ROS↓,
2524- H2,    Protective effect of hydrogen-rich water on liver function of colorectal cancer patients treated with mFOLFOX6 chemotherapy
- Trial, NA, NA
hepatoP↑, ALAT↓, AST↓, Dose↝, Dose↝,
2505- H2,    Hydrogen gas restores exhausted CD8+ T cells in patients with advanced colorectal cancer to improve prognosis
- Trial, CRC, NA
PGC-1α↑, Dose↝, CD8+↑, OS↑,
2504- H2,    Hydrogen gas activates coenzyme Q10 to restore exhausted CD8+ T cells, especially PD-1+Tim3+terminal CD8+ T cells, leading to better nivolumab outcomes in patients with lung cancer
- Trial, Lung, NA
CD8+↑, OS↑, eff↝, CoQ10↑, PDT+↓, PGC-1α↑, Dose↝, *toxicity∅,
3768- H2,    Effects of Hydrogen Gas Inhalation on Community-Dwelling Adults of Various Ages: A Single-Arm, Open-Label, Prospective Clinical Trial
- Trial, AD, NA
*ROS↓, *NO↓, *BACE↓, *BDNF↑, *VEGF↑, *p‑tau↓, *MCP1/CCL2↓, *IL6↓, *cognitive↑, *toxicity∅,
1438- HCQ,  Chemo,    Adding Chloroquine to Conventional Treatment for Glioblastoma Multiforme
- Trial, GBM, NA
OS↑, *toxicity∅,
7505- HCQ,  GEM,  PacT,    A Randomized Phase II Preoperative Study of Autophagy Inhibition with High-Dose Hydroxychloroquine and Gemcitabine/Nab-Paclitaxel in Pancreatic Cancer Patients
- Trial, PC, NA
eff↑, TumAuto↓, Imm↑, CA19-9↓, OS↑,
7349- HibSad,    Pharmacokinetics of anthocyanidin-3-glycosides following consumption of Hibiscus sabdariffa L. extract
- Trial, Nor, NA
*Dose↝, *Half-Life↓, *Half-Life↝, *BioAv↓, *antiOx↑, *BioAv↓,
7346- Hne,    Subcutaneous application of Helleborus niger 12x in older patients with dementia-a retrospective cohort study
- Trial, AD, NA
*cognitive↑,
7373- HOO,    Effects of topical ozonated olive oil on lipid profile, quality of life, wound healing and glycemic control in patients with diabetic foot ulcers: a randomized controlled trial
- Trial, Diabetic, NA
*Wound Healing↑, *QoL↑,
7477- HRT,    Cognitive effects of estradiol after menopause: A randomized trial of the timing hypothesis
- Trial, Nor, NA
*Dose↝, *memory∅, *cognitive∅,
7536- HT,    Effects of Desert Olive Tree Pearls Containing High Hydroxytyrosol Concentrations on the Cognitive Functions of Middle-Aged and Older Adults
- Trial, AD, NA
*Dose↑, *motorD↑, *cognitive↑, *Dose↝,
7543- HT,    Hydroxytyrosol supplementation increases vitamin C levels in vivo. A human volunteer trial
- Trial, Nor, NA
VitC↑,
7541- HT,    Hydroxytyrosol Supplementation Modifies Plasma Levels of Tissue Inhibitor of Metallopeptidase 1 in Women with Breast Cancer
- Trial, BC, NA
Dose↝, MMP9↓, TIMP1↓,
7526- HT,    Hydroxytyrosol in functional hydroxytyrosol-enriched biscuits is highly bioavailable and decreases oxidised low density lipoprotein levels in humans
- Trial, Nor, NA
*Half-Life↝, *BioAv↑, *Dose↝, *BioAv↝,
7524- HT,    The Pharmaceutical Formulation Plays a Pivotal Role in Hydroxytyrosol Pharmacokinetics
- Trial, Nor, NA
*Dose↝, *BioAv↝, *Half-Life↝, *toxicity↓, *BioAv↝, *BioAv↝,
4635- HT,    Hydroxytyrosol, a Component of Olive Oil for Breast Cancer Prevention in Women at High Risk of Cancer
- Trial, BC, NA
*Wnt↓, *NOTCH↓, *ROS↓, TumCP↓, CSCs↓,
7479- Hup,    A phase II trial of huperzine A in mild to moderate Alzheimer disease
- Trial, AD, NA
*Dose↝, *cognitive↑, *eff∅, *AChE↓,
7480- Hup,    Pharmacokinetics of huperzine A following oral administration to human volunteers
- Trial, AD, NA
*Dose↝, *BioAv↝, *Half-Life↝,
1272- LA,    Lactobacillus johnsonii N6.2 Modulates the Host Immune Responses: A Double-Blind, Randomized Trial in Healthy Adults
- Trial, Nor, NA
*Pain↓, *other↑,
3977- Lut,  Zeax,    Dietary carotenoids related to risk of incident Alzheimer dementia (AD) and brain AD neuropathology: a community-based cohort of older adults
- Trial, AD, NA
*Aβ↓, *cognitive↑, *Mood↑,
3978- Lut,  Zeax,    Effects of Lutein/Zeaxanthin Supplementation on the Cognitive Function of Community Dwelling Older Adults: A Randomized, Double-Masked, Placebo-Controlled Trial
- Trial, AD, NA
*cognitive↑, *Inflam↓,
3979- Lut,    Increases in Plasma Lutein through Supplementation Are Correlated with Increases in Physical Activity and Reductions in Sedentary Time in Older Adults
- Trial, AD, NA
*other↑, *QoL↑,
3980- Lut,  Zeax,    Supplementation With Carotenoids, Omega-3 Fatty Acids, and Vitamin E Has a Positive Effect on the Symptoms and Progression of Alzheimer's Disease
- Trial, AD, NA
*eff↑, *memory↑, *Mood↑, *QoL↑,
3981- Lut,  Zeax,  VitE,    Omega-3 fatty acid, carotenoid and vitamin E supplementation improves working memory in older adults: A randomised clinical trial
- Trial, AD, NA
*memory↑, *other↑, *cognitive↑,

Showing Research Papers: 201 to 250 of 334
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* indicates research on normal cells as opposed to diseased cells
Total Research Paper Matches: 334

Pathway results for Effect on Cancer / Diseased Cells:


NA, unassigned(tgid=0) ⓘ

IGF-2R↑, 1,   mal↓, 1,   miR-106b↓, 1,   Nausea↓, 4,   Nausea∅, 2,   NLR↓, 1,   ORR↑, 1,   PGI2↓, 1,   Vomit↓, 4,   Vomit∅, 2,  

Redox & Oxidative Stress(tgid=1) ⓘ

Bil∅, 1,   CoQ10↑, 1,   VitC↑, 1,  

Mitochondria & Bioenergetics(tgid=3) ⓘ

PGC-1α↑, 2,  

Core Metabolism/Glycolysis(tgid=4) ⓘ

ALAT↓, 1,  

Cell Death(tgid=5) ⓘ

p‑Akt↓, 1,   Apoptosis↑, 2,   Bcl-2↓, 3,   Bcl-xL↓, 2,   Mcl-1↓, 3,   NOXA↑, 1,   PUMA↑, 1,  

Transcription & Epigenetics(tgid=7) ⓘ

other↝, 1,  

Autophagy & Lysosomes(tgid=9) ⓘ

TumAuto↓, 1,  

Proliferation, Differentiation & Cell State(tgid=12) ⓘ

CSCs↓, 1,   PTEN↑, 1,  

Migration(tgid=13) ⓘ

5LO↓, 1,   AntiAg↝, 1,   Ki-67↓, 1,   miR-19b↓, 1,   MMP9↓, 1,   TIMP1↓, 1,   TumCP↓, 2,  

Immune & Inflammatory Signaling(tgid=16) ⓘ

COX2↓, 2,   CRP↓, 1,   IL6↓, 1,   Imm↑, 1,   Inflam↓, 2,   PDT+↓, 1,   PGE2↓, 1,   PSA↓, 2,  

Drug Metabolism & Resistance(tgid=21) ⓘ

BioAv↑, 1,   Dose↓, 1,   Dose↝, 16,   Dose∅, 1,   eff↓, 2,   eff↑, 3,   eff↝, 2,  

Clinical Biomarkers(tgid=22) ⓘ

ALAT↓, 1,   AST↓, 1,   Bil∅, 1,   CA19-9↓, 1,   CRP↓, 1,   IL6↓, 1,   Ki-67↓, 1,   PSA↓, 2,  

Functional Outcomes(tgid=23) ⓘ

AntiTum∅, 1,   cardioP↑, 1,   chemoPv↑, 2,   hepatoP↑, 1,   OS↑, 4,   QoL↑, 1,   radioP↑, 1,   toxicity↓, 1,   toxicity↝, 6,   toxicity∅, 1,  

Infection & Microbiome(tgid=24) ⓘ

CD8+↑, 2,  
Total Targets: 67

Pathway results for Effect on Normal Cells:


NA, unassigned(tgid=0) ⓘ

12-HETE↓, 1,   5-HETE↓, 1,   Eic↓, 1,  

Redox & Oxidative Stress(tgid=1) ⓘ

antiOx↑, 4,   ROS↓, 4,   uricA↓, 1,  

Core Metabolism/Glycolysis(tgid=4) ⓘ

LDL↓, 1,  

Transcription & Epigenetics(tgid=7) ⓘ

other↑, 4,   other↝, 2,  

Proliferation, Differentiation & Cell State(tgid=12) ⓘ

NOTCH↓, 1,   Wnt↓, 1,  

Angiogenesis & Vasculature(tgid=14) ⓘ

NO↓, 1,   VEGF↑, 1,  

Barriers & Transport(tgid=15) ⓘ

IBI↑, 1,  

Immune & Inflammatory Signaling(tgid=16) ⓘ

IL6↓, 1,   Inflam↓, 4,   MCP1/CCL2↓, 1,   PGE2↓, 1,  

Synaptic & Neurotransmission(tgid=18) ⓘ

AChE↓, 1,   BDNF↑, 1,   p‑tau↓, 1,  

Protein Aggregation(tgid=19) ⓘ

Aβ↓, 1,   BACE↓, 1,  

Drug Metabolism & Resistance(tgid=21) ⓘ

BioAv↓, 2,   BioAv↑, 2,   BioAv↝, 5,   Dose↓, 1,   Dose↑, 1,   Dose↝, 14,   eff↑, 3,   eff↝, 1,   eff∅, 1,   Half-Life↓, 2,   Half-Life↝, 6,  

Clinical Biomarkers(tgid=22) ⓘ

BP↓, 2,   IL6↓, 1,  

Functional Outcomes(tgid=23) ⓘ

AntiCan↑, 1,   AntiTum↑, 1,   cognitive↑, 10,   cognitive∅, 1,   memory↑, 2,   memory∅, 1,   Mood↑, 2,   motorD↑, 1,   Pain↓, 1,   QoL↑, 3,   toxicity↓, 5,   toxicity∅, 3,   Wound Healing↑, 1,  
Total Targets: 49

Query results interpretion may depend on "conditions" listed in the research papers.
Such Conditions may include : 
  -low or high Dose
  -format for product, such as nano of lipid formations
  -different cell line effects
  -synergies with other products 
  -if effect was for normal or cancerous cells

Filter Conditions: Pro/AntiFlg:%  IllCat:%  CanType:%  Cells:%  prod#:%  Target#:%  State#:%  Dir#:%
  wNotes=0  sortOrder:rid,rpid

 

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