| Source: |
| Type: |
| Drug dosage vs efficacy, and actual dosage number of research papers. |
| 5967- | CET, | FDA grants accelerated approval to adagrasib with cetuximab for KRAS G12C-mutated colorectal cancer |
| - | Study, | CRC, | NA |
| 6022- | CGA, | Chlorogenic Acid: Recent Advances on Its Dual Role as a Food Additive and a Nutraceutical against Metabolic Syndrome |
| - | Review, | Nor, | NA |
| 6019- | CGA, | immuno, | Combination immunotherapy of chlorogenic acid liposomes modified with sialic acid and PD-1 blockers effectively enhances the anti-tumor immune response and therapeutic effects |
| - | in-vivo, | Melanoma, | NA |
| 6037- | CGA, | Pharmacokinetics and brain penetration study of chlorogenic acid in rats |
| - | in-vivo, | AD, | NA | - | in-vivo, | Stroke, | NA |
| 6040- | CGA, | Protective effect of chlorogenic acid on cognitive impairment in rats with early Alzheimer's disease via Wnt signaling pathway |
| - | in-vivo, | AD, | NA |
| 6041- | CGA, | Effect of Chlorogenic Acid Intake on Cognitive Function in the Elderly: A Pilot Study |
| - | Trial, | AD, | NA |
| 6043- | CGA, | SeNPs, | Enhanced Effect of Combining Chlorogenic Acid on Selenium Nanoparticles in Inhibiting Amyloid β Aggregation and Reactive Oxygen Species Formation In Vitro |
| - | in-vitro, | AD, | NA |
| 6035- | CGA, | Effect of Chlorogenic Acids on Cognitive Function in Mild Cognitive Impairment: A Randomized Controlled Crossover Trial |
| - | Trial, | Nor, | NA |
| 6029- | CGA, | Pharmacokinetics of chlorogenic acids absorbed in human plasma and their metabolites following oral ingestion of coffee drink |
| - | Trial, | Nor, | NA |
| 6028- | CGA, | Chlorogenic acids from green coffee extract are highly bioavailable in humans |
| - | Trial, | Nor, | NA |
| 6001- | Chit, | Recent advances in engineering chitosan-based nanoplatforms in biotherapeutic multi-delivery for multi-targeted disease treatments: Promises and outlooks |
| - | Review, | Var, | HepG2 | - | Review, | AD, | NA |
| 6071- | CHL, | First-in-human clinical trial of high-dose sodium copper chlorophyllin: Pharmacology and efficacy as a dual immunomodulatory/antiviral agent |
| - | Trial, | Nor, | NA |
| 6083- | CHOC, | Preventive Effects of Cocoa and Cocoa Antioxidants in Colon Cancer |
| - | Review, | Colon, | NA |
| 6087- | CHOC, | Effect of cocoa flavanol supplementation for the prevention of cardiovascular disease events: the COcoa Supplement and Multivitamin Outcomes Study (COSMOS) randomized clinical trial |
| - | Trial, | Nor, | NA |
| - | Trial, | Nor, | NA |
| 6090- | CHOC, | Cocoa Flavanol Intake and Biomarkers for Cardiometabolic Health: A Systematic Review and Meta-Analysis of Randomized Controlled Trials |
| - | Review, | Nor, | NA |
| 6107- | Chol, | Choline supplements: An update |
| - | Review, | AD, | NA |
| 6111- | Chol, | The gut microbiota-derived metabolite trimethylamine N-oxide is elevated in Alzheimer’s disease |
| - | Human, | AD, | NA |
| 6113- | Chol, | Association between choline supplementation and Alzheimer’s disease risk: a systematic review protocol |
| - | Review, | AD, | NA |
| 6108- | Chol, | Trimethylamine-N-Oxide (TMAO) as a Rising-Star Metabolite: Implications for Human Health |
| - | Review, | Nor, | NA | - | Review, | AD, | NA |
| 6114- | Chol, | Dietary Choline Intake and Risk of Alzheimer's Dementia in Older Adults |
| - | Study, | AD, | NA |
| 6115- | Chol, | Association of dietary choline intake with incidence of dementia, Alzheimer disease, and mild cognitive impairment: a large population-based prospective cohort study |
| - | Study, | AD, | NA |
| 6117- | Chol, | Citicoline and Memory Function in Healthy Older Adults: A Randomized, Double-Blind, Placebo-Controlled Clinical Trial |
| - | Trial, | AD, | NA |
| 6120- | Chol, | Citicoline: A Cholinergic Precursor with a Pivotal Role in Dementia and Alzheimer’s Disease |
| - | Trial, | AD, | NA |
| 6101- | Chol, | Effect of Choline Forms and Gut Microbiota Composition on Trimethylamine-N-Oxide Response in Healthy Men |
| - | Human, | Nor, | NA |
| 6098- | Chol, | Choline |
| - | Review, | Nor, | NA | - | Review, | AD, | NA |
| 3701- | Chol, | Lifelong choline supplementation ameliorates Alzheimer's disease pathology and associated cognitive deficits by attenuating microglia activation |
| - | in-vivo, | AD, | NA |
| 6134- | CHr, | QC, | RT, | Comparative Pharmacokinetics and Safety of a Micellar Chrysin–Quercetin–Rutin Formulation: A Randomized Crossover Trial |
| - | Trial, | Nor, | NA |
| 6122- | CHr, | Disposition and metabolism of the flavonoid chrysin in normal volunteers |
| - | Human, | Nor, | NA |
| 2806- | CHr, | Se, | Selenium-containing chrysin and quercetin derivatives: attractive scaffolds for cancer therapy |
| - | in-vitro, | Var, | NA |
| 2784- | CHr, | Chrysin targets aberrant molecular signatures and pathways in carcinogenesis (Review) |
| - | Review, | Var, | NA |
| 6627- | Cic, | Determination of Cichoric Acid as a Biomarker in Echinacea Purpurea Cultivated in Iran Using High Performance Liquid Chromatography |
| - | Study, | Nor, | NA |
| 6629- | Cic, | Chicoric Acid: Natural Occurrence, Chemical Synthesis, Biosynthesis, and Their Bioactive Effects |
| - | Review, | Nor, | NA |
| 6140- | Cin, | HCAs, | Cinnamaldehyde: Pharmacokinetics, anticancer properties and therapeutic potential (Review) |
| - | Review, | Var, | NA |
| 6148- | Citrate, | immuno, | Sodium Citrate Nanoparticles Induce Dual-Path Pyroptosis for Enhanced Antitumor Immunotherapy through Synergistic Ion Overload and Metabolic Disturbance |
| - | in-vitro, | Var, | NA |
| 1583- | Citrate, | Extracellular citrate and metabolic adaptations of cancer cells |
| - | Review, | NA, | NA |
| 1586- | Citrate, | Extracellular Citrate Is a Trojan Horse for Cancer Cells |
| - | in-vitro, | Liver, | HepG2 |
| 1582- | Citrate, | Clinical report: A patient with primary peritoneal mesothelioma that has improved after taking citric acid orally |
| - | Case Report, | PerC, | NA |
| 1581- | Citrate, | Hypothesis proved. . .citric acid (citrate) does improve cancer:A case of a patient suffering from medullary thyroid cancer |
| - | Case Report, | Thyroid, | NA |
| 1578- | Citrate, | Understanding the Central Role of Citrate in the Metabolism of Cancer Cells and Tumors: An Update |
| - | Review, | Var, | NA |
| 1576- | Citrate, | Targeting citrate as a novel therapeutic strategy in cancer treatment |
| - | Review, | Var, | NA |
| 1574- | Citrate, | Citrate Suppresses Tumor Growth in Multiple Models through Inhibition of Glycolysis, the Tricarboxylic Acid Cycle and the IGF-1R Pathway |
| - | in-vitro, | Lung, | A549 | - | in-vitro, | Melanoma, | WM983B | - | in-vivo, | NA, | NA |
| 3994- | CoQ10, | Se, | Coenzyme Q10 Supplementation in Aging and Disease |
| - | Review, | AD, | NA | - | Review, | Park, | NA |
| 4763- | CoQ10, | Chemo, | doxoR, | Effect of Coenzyme Q10 on Doxorubicin Cytotoxicity in Breast Cancer Cell Cultures |
| - | in-vitro, | BC, | MDA-MB-231 | - | in-vitro, | BC, | BT549 |
| 4768- | CoQ10, | Role of coenzymes in cancer metabolism |
| - | Review, | Var, | NA |
| 4769- | CoQ10, | CoQ10 Is Key for Cellular Energy and Cancer Support |
| - | Review, | Var, | NA |
| 6373- | CPLE, | Anticancer Activity of Phytochemicals of the Papaya Plant Assessed: A Narrative Review |
| - | Review, | Var, | NA |
| 5808- | CPT, | Repair of Topoisomerase I-Mediated DNA Damage |
| - | Review, | Var, | NA |
| 5791- | CRMs, | HCA, | NAD, | Sper, | RES | Caloric Restriction Mimetics in Nutrition and Clinical Trials |
| - | Review, | Nor, | NA |
| 5792- | CRMs, | HCA, | CUR, | EGCG, | GAR | Caloric restriction mimetics: natural/physiological pharmacological autophagy inducers |
| - | Review, | Nor, | NA |
Query results interpretion may depend on "conditions" listed in the research papers.
Such Conditions may include :
-low or high Dose
-format for product, such as nano of lipid formations
-different cell line effects
-synergies with other products
-if effect was for normal or cancerous cells
Filter Conditions: Pro/AntiFlg:% IllCat:% CanType:% Cells:% prod#:% Target#:1114 State#:% Dir#:%
wNotes=0 sortOrder:rid,rpid