| Source: |
| Type: type of cell death |
| Situation in which a cell actively pursues a course toward death upon receiving certain stimuli. Cancer is one of the scenarios where too little apoptosis occurs, resulting in malignant cells that will not die. |
| 3170- | Ash, | Withaferin A protects against hyperuricemia induced kidney injury and its possible mechanisms |
| - | in-vitro, | Nor, | NRK52E | - | in-vivo, | NA, | NA |
| 5384- | AsP, | MLT, | Synergistic Anticancer Effect of Melatonin and Ascorbyl Palmitate Nanoformulation: A Promising Combination for Cancer Therapy |
| - | in-vivo, | Var, | NA |
| 5389- | AsP, | Tras, | ASCORBYL PALMITATE ENHANCES ANTI-PROLIFERATIVE EFFECT OF TRASTUZUMAB IN HER2-POSITIVE BREAST CANCER CELLS |
| - | in-vitro, | BC, | NA |
| 5387- | AsP, | PacT, | Ascorbyl palmitate-incorporated paclitaxel-loaded composite nanoparticles for synergistic anti-tumoral therapy |
| - | in-vivo, | Melanoma, | B16-F10 |
| 1146- | AsP, | Potential use of nanoformulated ascorbyl palmitate as a promising anticancer agent: First comparative assessment between nano and free forms |
| - | in-vivo, | Nor, | NA |
| 5419- | ASTX, | Astaxanthin and other Nutrients from Haematococcus pluvialis—Multifunctional Applications |
| - | Review, | Nor, | NA |
| 4814- | ASTX, | Chemopreventive and therapeutic efficacy of astaxanthin against cancer: A comprehensive review |
| - | Review, | Var, | NA |
| 4823- | ASTX, | Astaxanthin increases radiosensitivity in esophageal squamous cell carcinoma through inducing apoptosis and G2/M arrest |
| - | in-vitro, | ESCC, | NA |
| 4821- | ASTX, | Astaxanthin Reduces Stemness Markers in BT20 and T47D Breast Cancer Stem Cells by Inhibiting Expression of Pontin and Mutant p53 |
| - | in-vitro, | BC, | SkBr3 | - | in-vitro, | BC, | BT20 | - | in-vitro, | BC, | T47D |
| 4820- | ASTX, | Astaxanthin suppresses the malignant behaviors of nasopharyngeal carcinoma cells by blocking PI3K/AKT and NF-κB pathways via miR-29a-3p |
| - | in-vitro, | NPC, | NA |
| 4819- | ASTX, | Astaxanthin Induces Apoptosis in MCF-7 Cells through a p53-Dependent Pathway |
| - | in-vitro, | BC, | MCF7 |
| 4818- | ASTX, | MLT, | Effect of astaxanthin and melatonin on cell viability and DNA damage in human breast cancer cell lines |
| - | in-vitro, | BC, | MDA-MB-231 | - | in-vitro, | BC, | T47D | - | in-vitro, | Nor, | MCF10 |
| 4804- | ASTX, | Astaxanthin in cancer therapy and prevention (Review) |
| - | Review, | Var, | NA | - | Review, | AD, | NA |
| 4813- | ASTX, | Astaxanthin Prevents Oxidative Damage and Cell Apoptosis Under Oxidative Stress Involving the Restoration of Mitochondrial Function |
| - | in-vitro, | AD, | NA |
| 4812- | ASTX, | Astaxanthin suppresses the metastasis of colon cancer by inhibiting the MYC-mediated downregulation of microRNA-29a-3p and microRNA-200a |
| - | in-vitro, | CRC, | HCT116 |
| 4808- | ASTX, | Anti-Tumor Effects of Astaxanthin by Inhibition of the Expression of STAT3 in Prostate Cancer |
| - | in-vitro, | Pca, | DU145 | - | in-vivo, | NA, | NA |
| 4807- | ASTX, | An overview of the anticancer activity of astaxanthin and the associated cellular and molecular mechanisms |
| - | Review, | Var, | NA |
| 4806- | ASTX, | Astaxanthin's Impact on Colorectal Cancer: Examining Apoptosis, Antioxidant Enzymes, and Gene Expression |
| - | in-vitro, | CRC, | HCT116 |
| 4805- | ASTX, | Astaxanthin promotes apoptosis by suppressing growth signaling pathways in HT-29 colorectal cancer cells |
| - | in-vitro, | Colon, | HT29 |
| 5448- | ATV, | Beyond cardiovascular health: The pharmacotherapeutic potential of statins in oncology |
| - | Review, | Var, | NA |
| 5449- | ATV, | Pleiotropic effects of statins: A focus on cancer |
| - | Review, | Var, | NA |
| 4981- | ATV, | Crosstalk between Statins and Cancer Prevention and Therapy: An Update |
| - | Review, | Var, | NA |
| 4978- | ATV, | Rad, | Atorvastatin Sensitizes Breast and Lung Cancer Cells to Ionizing Radiation |
| - | in-vitro, | BC, | A549 |
| 4986- | ATV, | Dipy, | The combination of statins and dipyridamole is effective preclinically in AML, MM, and breast cancer |
| - | Review, | Var, | NA |
| 5362- | AV, | Anti-cancer effects of aloe-emodin: a systematic review |
| - | Review, | Var, | NA |
| 5363- | AV, | Exploring the mechanism of aloe-emodin in the treatment of liver cancer through network pharmacology and cell experiments |
| - | Study, | HCC, | NA |
| 5571- | B-Gluc, | immuno, | Potential benefit of β-glucans as adjuvant therapy in immuno-oncology: a review |
| - | Review, | Var, | NA |
| 5567- | B-Gluc, | Trained immunity: A new player in cancer immunotherapy |
| - | Review, | Var, | NA |
| 996- | Ba, | Tam, | Baicalein resensitizes tamoxifen‐resistant breast cancer cells by reducing aerobic glycolysis and reversing mitochondrial dysfunction via inhibition of hypoxia‐inducible factor‐1α |
| - | in-vitro, | BC, | NA |
| - | in-vivo, | BC, | 4T1 |
| 5498- | Ba, | Inhibition of 12-lipoxygenase during baicalein-induced human lung nonsmall carcinoma H460 cell apoptosis |
| - | in-vitro, | Lung, | H460 |
| 5505- | Ba, | Baicalein inhibits the progression of thyroid cancer by suppressing the TPL2/MEK2/ERK2 pathway |
| - | in-vitro, | Thyroid, | NA |
| 5501- | Ba, | Therapeutic effects and mechanisms of action of Baicalein on stomach cancer: a comprehensive systematic literature review |
| - | Review, | GC, | NA |
| 5499- | Ba, | Anti-cancer effects of baicalein in non-small cell lung cancer in-vitro and in-vivo |
| - | vitro+vivo, | Lung, | H460 | - | vitro+vivo, | Lung, | A549 |
| 5248- | Ba, | BA, | doxoR, | Baicalin and Baicalein Enhance Cytotoxicity, Proapoptotic Activity, and Genotoxicity of Doxorubicin and Docetaxel in MCF-7 Breast Cancer Cells |
| - | in-vitro, | BC, | MCF7 | - | in-vitro, | Nor, | HUVECs |
| 5249- | Ba, | BA, | Baicalein and baicalin in cancer therapy: Multifaceted mechanisms, preclinical evidence, and translational challenges |
| - | Review, | Var, | NA |
| 5250- | Ba, | Exploring baicalein: A natural flavonoid for enhancing cancer prevention and treatment |
| - | Review, | Var, | NA |
| 1288- | Ba, | The Traditional Chinese Medicine Baicalein Potently Inhibits Gastric Cancer Cells |
| - | in-vitro, | GC, | SGC-7901 |
| 1533- | Ba, | Baicalein, as a Prooxidant, Triggers Mitochondrial Apoptosis in MCF-7 Human Breast Cancer Cells Through Mobilization of Intracellular Copper and Reactive Oxygen Species Generation |
| - | in-vitro, | BrCC, | MCF7 | - | in-vitro, | Nor, | MCF10 |
| 1532- | Ba, | Baicalein as Promising Anticancer Agent: A Comprehensive Analysis on Molecular Mechanisms and Therapeutic Perspectives |
| - | Review, | Var, | NA |
| 1528- | Ba, | Inhibiting reactive oxygen species-dependent autophagy enhanced baicalein-induced apoptosis in oral squamous cell carcinoma |
| - | in-vitro, | OS, | CAL27 |
| 1526- | Ba, | Baicalein induces apoptosis through ROS-mediated mitochondrial dysfunction pathway in HL-60 cells |
| - | in-vitro, | AML, | HL-60 |
| - | in-vitro, | Lung, | H1975 | - | in-vivo, | Lung, | NA |
| - | in-vitro, | Lung, | A549 |
| 1523- | Ba, | Baicalein induces human osteosarcoma cell line MG-63 apoptosis via ROS-induced BNIP3 expression |
| - | in-vitro, | OS, | MG63 | - | in-vitro, | Nor, | hFOB1.19 |
| 1521- | Ba, | Baicalein induces apoptosis via ROS-dependent activation of caspases in human bladder cancer 5637 cells |
| - | in-vitro, | Bladder, | 5637 |
| 1519- | Ba, | Baicalein inhibits KB oral cancer cells by inducing apoptosis via modulation of ROS |
| - | in-vitro, | Oral, | KB |
| 2474- | Ba, | Anticancer properties of baicalein: a review |
| - | Review, | Var, | NA | - | in-vitro, | Nor, | BV2 |
| 2476- | Ba, | Baicalein Induces Caspase-dependent Apoptosis Associated with the Generation of ROS and the Activation of AMPK in Human Lung Carcinoma A549 Cells |
| - | in-vitro, | Lung, | A549 |
| 2769- | Ba, | Rad, | Baicalein ameliorates ionizing radiation-induced injuries by rebalancing gut microbiota and inhibiting apoptosis |
| - | in-vivo, | Nor, | NA |
Query results interpretion may depend on "conditions" listed in the research papers. Such Conditions may include : -low or high Dose -format for product, such as nano of lipid formations -different cell line effects -synergies with other products -if effect was for normal or cancerous cells
Filter Conditions: Pro/AntiFlg:% IllCat:% CanType:% Cells:% prod#:% Target#:14 State#:% Dir#:%
wNotes=0 sortOrder:rid,rpid