MMP9 Cancer Research Results

MMP9, MMP9: Click to Expand ⟱
Source: HalifaxProj(suppress)
Type:
Matrix metalloproteinase-9 (MMP-9) is an enzyme that plays a significant role in the degradation of extracellular matrix components.
MMP-9 facilitates the breakdown of the extracellular matrix, which can enable cancer cells to invade surrounding tissues and spread to distant sites (metastasis).
Elevated levels of MMP-9 have been associated with poor prognosis in several cancers, including breast, lung, and colorectal cancers.
MMP2 and MMP9: two enzymes are critical to tumor invasion.
Scientific Papers found: Click to Expand⟱
2830- FIS,    Biological effects and mechanisms of fisetin in cancer: a promising anti-cancer agent
- Review, Var, NA
TumCG↓, angioG↓, *ROS↓, TumCMig↓, VEGF↓, MAPK↑, NF-kB↓, PI3K↓, Akt↓, mTOR↓, NRF2↑, HO-1↑, ROS↓, Inflam↓, ER Stress↑, ROS↑, TumCP↓, ChemoSen↑, PTEN↑, P53↑, Casp3↑, Casp8↑, Casp9↑, COX2/PTGS2↓, Wnt↓, EGFR↓, Mcl-1↓, survivin↓, IAP1↓, IAP2/BIRC3↓, PGE2↓, β-catenin/ZEB1↓, DR5↑, MMP2↓, MMP9↓, FAK↓, uPA↓, EMT↓, ERK↓, JNK↑, p38↑, PKCδ↓, BioAv↓, BioAv↑, BioAv↑,
2839- FIS,    Dietary flavonoid fisetin for cancer prevention and treatment
- Review, Var, NA
DNAdam↑, ROS↑, Apoptosis↑, Bcl-2↓, BAX↑, cl‑Casp9↑, cl‑Casp3↑, Cyt‑c↑, lipid-P↓, TumCG↓, TumCA↓, TumCMig↓, TumCI↓, uPA↓, ERK↓, MMP9↓, NF-kB↓, cFos↓, cJun↓, AP-1↓, TumCCA↑, AR↓, mTORC1↓, mTORC2↓, TSC2↑, EGF↓, TGF-β↓, EMT↓, P-gp/ABCB1↓, PI3K↓, Akt↓, mTOR↓, Synergy↑, ROS↓, ER Stress↑, IRE1↑, ATF4↑, GRP78/BiP↑, ChemoSen↑, CDK2↓, CDK4↓, cycE/CCNE↓, cycD1/CCND1↓, P21↑, COX2/PTGS2↓, Wnt↓, EGFR↓, β-catenin/ZEB1↓, TCF-4↓, MMP7↓, RadioS↑, Synergy↑,
2843- FIS,    Fisetin and Quercetin: Promising Flavonoids with Chemopreventive Potential
- Review, Var, NA
NRF2↑, Keap1↓, ChemoSen↑, BioAv↓, Cyt‑c↑, Casp3↑, Casp9↑, BAX↑, tumCV↓, Mcl-1↓, cl‑PARP↑, IGF-1↓, Akt↓, CDK6↓, TumCCA↑, P53?, cycD1/CCND1↓, cycE/CCNE↓, CDK2↓, CDK4↓, CDK6↓, MMP2↓, MMP9↓, MMP1↓, MMP7↓, MMP3↓, VEGF↓, PI3K↓, mTOR↓, COX2/PTGS2↓, Wnt↓, EGFR↓, NF-kB↓, ERK↓, ROS↑, angioG↓, TNF-α↓, PGE2↓, iNOS↓, NO↓, IL6↓, HSP70/HSPA5↝, HSP27↝,
2832- FIS,    Fisetin's Promising Antitumor Effects: Uncovering Mechanisms and Targeting for Future Therapies
- Review, Var, NA
MMP↓, mtDam↑, Cyt‑c↑, Diablo↑, Casp↑, cl‑PARP↑, Bak↑, BIM↑, Bcl-xL↓, Bcl-2↓, P53↑, ROS↑, AMPK↑, Casp9↑, Casp3↑, BID↑, AIF↑, Akt↓, mTOR↓, MAPK↓, Wnt↓, β-catenin/ZEB1↓, TumCCA↑, P21↑, p27/CDKN1B↑, cycD1/CCND1↓, cycE/CCNE↓, CDK2↓, CDK4↓, CDK6↓, TumMeta↓, uPA↓, E-cadherin↑, Vim↓, EMT↓, Twist↓, DNAdam↑, ROS↓, COX2/PTGS2↓, PGE2↓, HSF1↓, cFos↓, cJun↓, AP-1↓, Mcl-1↓, NF-kB↓, IRE1↑, ER Stress↑, ATF4↑, GRP78/BiP↑, MMP2↓, MMP9↓, TCF-4↓, MMP7↓, RadioS↑, TOP1↓, TOP2↓,
6978- Form,    Formononetin promotes angiogenesis through the estrogen receptor alpha-enhanced ROCK pathway
- vitro+vivo, Nor, HUVECs
*angioG↑, *VEGF↑, *MYPT1 / PPP1R12A↑, *MMP2↑, *MMP9↑, *p‑MYPT1 / PPP1R12A↑, *p‑MLC2/MYL9↑, *p‑LIMK1↑, *p‑Cofilin↑, *ROCK1↑,
6982- Form,    Formononetin: A Review of Its Anticancer Potentials and Mechanisms
- Review, Var, NA
AntiTum↑, Apoptosis↑, BAX↑, Bcl-2↓, Casp3↑, TumCCA↑, cycA1/CCNA1↓, CycB/CCNB1↓, cycD1/CCND1↓, TumCP↓, VEGF↓, FGF↓, MMP2↓, MMP9↓, Synergy↑, ChemoSen↑, chemoPv↑, p‑Akt↓, p‑STAT3↑, TumCMig↓, TumCI↓, TIMP1↑, TIMP2↑, PI3K↓, Akt↓, Dose↝, TumCG↓, TumW↓, TumVol↓, angioG↓, Casp3↑, Casp9↑, cl‑PARP↑, DNArepair↓, MMP↓, BAX↑, Bcl-2↓, DR5↑, ROS↑, eff↓, p‑ERK↓, PTEN↑, Hif1a↓, eff↑, Synergy↑, ChemoSen↑, HDAC↓, *BioAv↑, *Half-Life↝, *BioAv↝, *BioAv↑, *BioAv↑, *eff↑,
6970- Form,    Formononetin, an isoflavone from Astragalus membranaceus inhibits proliferation and metastasis of ovarian cancer cells
- in-vitro, Ovarian, NA
tumCV↓, Apoptosis↑, Casp3↑, Casp9↑, Bax:Bcl2↑, TumCMig↓, TumCI↓, MMP2↓, MMP9↓, p‑ERK↓,
6965- Form,    Formononetin inhibits colon carcinoma cell growth and invasion by microRNA‑149‑mediated EphB3 downregulation and inhibition of PI3K/AKT and STAT3 signaling pathways
- in-vitro, CRC, HCT116
TumCP↓, TumCI↓, cycD1/CCND1↓, TumCCA↑, MMP2↓, MMP9↓, miR-149↑, tumCV↓, p‑PI3K↓, p‑Akt↓, p‑STAT3↓,
6967- Form,  BTZ,    Formononetin Regulates Multiple Oncogenic Signaling Cascades and Enhances Sensitivity to Bortezomib in a Multiple Myeloma Mouse Model
- in-vivo, Melanoma, U266 - in-vivo, Melanoma, RPMI-8226
Synergy↑, NF-kB↓, PI3K↓, Akt↓, AP-1↓, COX2/PTGS2↓, MMP9↓, Casp3↑, cl‑PARP↑, Dose↝, Ki-67↓, VEGF↓,
8588- FS,  Tam,    Dietary flaxseed and tamoxifen affect the inflammatory microenvironment in vivo in normal human breast tissue of postmenopausal women
- in-vivo, BC, NA
BioAv↑, Dose↝, IL-1Ra↑, IL1R2↑, IL18↑, IL1RL1/ST2↑, MMP9↑, eff↑,
7010- Fuc,    Fucoidan enhances the effect of chemotherapeutic drug against drug-resistant lung cancer cells
- in-vitro, Lung, NA
ChemoSen↑, MMP9↓, Apoptosis↑, LC3s↓, Beclin-1/ATG6↓, β-catenin/ZEB1↓, TumCP↓, TumCMig↓, TumMeta↓,
7005- Fuc,    Fucoidan and cancer: a multifunctional molecule with anti-tumor potential
- Review, Var, NA
AntiCan↑, TumCCA↑, cycD1/CCND1↓, CDK4↓, MMP↓, Casp9↑, survivin↓, IAP1↓, Cyt‑c↑, Diablo↑, Bak↑, XIAP↓, VEGF↓, angioG↓, MMP2↓, MMP9↓, Akt↓, eff↝, TumMeta↓,
7041- GA,    Gallic acid suppresses the progression of clear cell renal cell carcinoma through inducing autophagy via the PI3K/Akt/Atg16L1 signaling pathway
- vitro+vivo, RCC, 786-O - in-vitro, RCC, ACHN - in-vitro, Nor, HK-2
selectivity↑, TumCP↓, TumCMig↓, TumCI↓, TumCCA↑, TumVol↓, TumW↓, Ki-67↓, MMP9↓, TumAuto↑, LC3B-II↓, Beclin-1/ATG6↓, p62↑,
5148- GamB,    Gambogic acid: A shining natural compound to nanomedicine for cancer therapeutics
- Review, Var, NA
AntiCan↑, angioG↓, ChemoSen↑, RadioS↑, VEGF↓, MMP2↓, MMP9↓, Telomerase↓, TrxR↓, ERK↓, HSP90↓, ROS↑, SIRT1↑, survivin↓, cFLIP↓, Casp3↑, Casp8↑, Casp9↑, BAD↓, BID↓, Bcl-2↓, BAX↑, STAT3↓, hTERT/TERT↓, NF-kB↓, Myc↓, Hif1a↓, FOXD3↑, BioAv↓, BioAv↑, P53↑, eff↓, OCR↓, MMP↓, PI3K↓, Akt↓, BBB↑, TumCG↓, TumMeta↓, BioAv↑,
5150- GamB,    Gambogic acid, a novel ligand for transferrin receptor, potentiates TNF-induced apoptosis through modulation of the nuclear factor-κB signaling pathway
- in-vitro, CLL, KBM-5 - in-vitro, Nor, HEK293
Apoptosis↑, ChemoSen↑, IAP1↓, IAP2/BIRC3↓, Bcl-2↓, Bcl-xL↓, TRAF1↓, cycD1/CCND1↓, cMyc↓, COX2/PTGS2↓, MMP9↓, angioG↓, VEGF↓, NF-kB↓, eff↓,
2426- GamB,    Anti-cancer natural products isolated from chinese medicinal herbs
- Review, Var, NA
TfR1/CD71↓, MMP2↓, MMP9↓, ChemoSen↑,
7065- GamB,    Gambogic acid: A review of its pharmacological mechanisms against cancer
- Review, Var, NA
AntiTum↑, Apoptosis↑, TumCCA↑, angioG↓, Hif1a↓, VEGF↓, MMPs↓, TumMeta↓, NF-kB↓, PI3K↓, Akt↓, mTOR↓, MAPK↓, P-gp/ABCB1↓, Shh↓, Pyro↑, Casp3↑, GSDME↑, ChemoSen↑, RadioS↑, BioAv↓, Bcl-2↓, Mcl-1↓, BAX↑, Half-Life↓, ROS↑, miR-21↓, MMP2↓, MMP9↓,
7067- GamB,    Gambogic Acid and Its Role in Chronic Diseases
- Review, Var, NA
*NF-kB↓, PI3K↓, Akt↓, STAT3↓, STAT5↓, IL6↓, COX2/PTGS2↓, iNOS↓, MMPs↓, Src↓, PKA↓, CXCR4↑, VEGF↓, Bcl-2↓, Bcl-xL↓, IAP1↓, Mcl-1↓, survivin↓, cycD1/CCND1↓, HSP90↓, HSP70/HSPA5↓, MAPK↓, HATs↓, HDAC↓, FAK↓, ROS↑, MMP7↓, MMP9↓, α-tubulin↑, cl‑PARP↑, TNF-α↓, BID↑, BAD↑, Cyt‑c↑, Casp3↑, Casp9↑, *AntiArt↑, *antiPs↑,
7086- GAR,    Garcinol: An emerging epigenetic modifier with versatile anticancer properties
- Review, Var, NA
AntiCan↑, TumCG↓, TumMeta↓, toxicity↓, Apoptosis↑, angioG↓, *BioAv↝, HATs↓, p300↓, CBP↓, PI3K↓, Akt↓, NF-kB↓, STAT↓, mTOR↓, DFF45↓, survivin↓, N-cadherin↓, Twist↓, MMP2↓, MMP3↓, MMP9↓, Mcl-1↓, EZH2↓, NOTCH↓, CXCR4↓, PGE2↓, VEGF↓, mPGES-1↓, CycB/CCNB1↓, CDK2↓, CDK4/6↓, iNOS↓, COX2/PTGS2↓, IL1↓, TNF-α↓, PARP↑, Bcl-2↓, CompStab↝,
7089- GAR,    Anticancer action of garcinol in vitro and in vivo is in part mediated through inhibition of STAT-3 signaling
- vitro+vivo, BC, MDA-MB-231 - in-vitro, Pca, DU145 - in-vitro, PC, NA
STAT3↓, TumCI↓, NF-kB↓, uPA↓, VEGF↓, MMP9↓,
811- GAR,    Garcinol exhibits anti-proliferative activities by targeting microsomal prostaglandin E synthase-1 in human colon cancer cells
- in-vitro, CRC, HT-29
mPGES-1↓, Hif1a↓, VEGF↓, CXCR4↓, MMP2↓, MMP9↓, Casp3↑, TumCP↓, PGE2↓,
805- GAR,  Cisplatin,  PacT,    Garcinol Exhibits Anti-Neoplastic Effects by Targeting Diverse Oncogenic Factors in Tumor Cells
- Review, Var, NA
ERK↓, PI3K/Akt↓, Wnt/(β-catenin)↓, STAT3↓, NF-kB↓, ChemoSen↑, COX2/PTGS2↓, Casp3↑, Casp9↑, BAX↑, Bcl-2↓, VEGF↓, TGF-β↓, HATs↓, E-cadherin↑, Vim↓, Zeb1↓, ZEB2↓, Let-7↑, MMP9↓, TumCCA↑, ROS↑, MMP↓, IL6↓, NOTCH1↓, antiNeop↑,
802- GAR,    Garcinol acts as an antineoplastic agent in human gastric cancer by inhibiting the PI3K/AKT signaling pathway
- in-vitro, GC, HGC27
TumCP↓, TumCI↓, Apoptosis↑, PI3K/Akt↓, Akt↓, p‑mTOR↓, cycD1/CCND1↓, MMP2↓, MMP9↓, BAX↑, Bcl-2↓,
812- GAR,    Anti-proliferative and anti-invasive effects of garcinol from Garcinia indica on gallbladder carcinoma cells
- in-vitro, Gall, GBC-SD - in-vitro, Gall, NOZ
TumCG↓, TumCI↓, MMP2↓, MMP9↓,
820- GAR,    Garcinol in gastrointestinal cancer prevention: recent advances and future prospects
- Review, GC, NA
Fas↑, TRAIL↑, PARP↑, BAX↑, Bcl-2↓, ROS↑, STAT3↓, Apoptosis↑, MMP2↓, MMP9↓,
795- GAR,    Garcinol—A Natural Histone Acetyltransferase Inhibitor and New Anti-Cancer Epigenetic Drug
- Review, Var, NA
HATs↓, BAX↑, PARP↑, Bcl-2↓, Casp3↑, Casp9↑, DR5↑, cFLIP↓, MMP2↓, MMP9↓, STAT3↓, p‑Akt↓,
7213- GAs,    Anti-Cancer Properties of Ginkgolic Acids in Human Nasopharyngeal Carcinoma CNE-2Z Cells via Inhibition of Heat Shock Protein 90
- vitro+vivo, NPC, CNE2 - in-vitro, BC, MDA-MB-231 - in-vitro, BC, MCF7 - in-vitro, Lung, H1975
ATPase↓, HSP90↓, TumCP↓, *toxicity↝, MMP2↓, MMP9↓, HER2/EBBR2↓, c-Raf↓, Akt↓, Bcl-2↓, other↝,
7224- GAs,    Ginkgolic acids inhibit migration in breast cancer cells by inhibition of NEMO sumoylation and NF-κB activity
- in-vitro, BC, MCF7 - in-vitro, BC, MDA-MB-231
Wound Healing↓, uPA↓, PAI-1/SERPINE1↓, CXCR4↓, MMP9↓, TumCMig↓, NF-kB↓,
7223- GBE,    Ginkgo biloba Exocarp Extract Inhibits the Metastasis of B16-F10 Melanoma Involving PI3K/Akt/NF- κ B/MMP-9 Signaling Pathway
- vitro+vivo, Melanoma, B16-F10
TumCP↓, TumCMig↓, p‑PI3K↓, p‑Akt↓, NF-kB↓, MMP9↓, TumMeta↓, Dose↝,
7103- GEN,    A Comprehensive Review of Genistein's Effects in Preclinical Models of Cervical Cancer
- Review, Cerv, NA
TumCP↓, Apoptosis↑, RadioS↑, ChemoSen↑, *antiOx↑, *Inflam↓, *Bacteria↓, *AntiViral↑, *AntiDiabetic↑, *neuroP↑, AntiCan↑, TumCG↓, TumCI↓, TumCCA↑, cl‑PARP↑, selectivity↑, CycB/CCNB1↓, CDK1↓, p‑cDC2↓, p‑ERK↓, p‑p38↑, p‑JNK↑, MMP9↓, TIMP1↑, BioAv↓, BioAv↑, Half-Life↑,
2998- GEN,    Cellular and Molecular Mechanisms Modulated by Genistein in Cancer
- Review, Var, NA
Hif1a↓, VEGF↓, PDGF↓, uPA↓, MMP2↓, MMP9↓, chemoPv↑, TumCI↓, TumMeta↓, NF-kB↓, AP-1↓, IKKα↓, PI3K↓, Akt↓, EMT↓, CSCs↓,
6567- Ger,    Geraniin inhibits proliferation and induces apoptosis through inhibition of phosphatidylinositol 3-kinase/Akt pathway in human colorectal cancer in vitro and in vivo
- vitro+vivo, CRC, SW480 - in-vitro, CRC, HT29
AntiTum↑, *Inflam↓, *antiOx↓, TumCP↓, BAX↑, Casp3↑, Casp9↑, Bcl-2↓, TumCMig↓, TumCI↓, MMP2↓, MMP9↓, p‑PI3K↓, p‑Akt↓, Dose↝, TumCG↓,
7138- GI,    6-Shogaol exerts anti-proliferative and pro-apoptotic effects through the modulation of STAT3 and MAPKs signaling pathways
- vitro+vivo, BC, MDA-MB-231 - in-vitro, Pca, DU145 - in-vitro, Liver, HepG2 - in-vitro, Lung, A549
TumCP↓, TumMeta↓, p‑STAT3↓, JAK2↓, cSrc↓, JNK↑, p38↑, ERK↑, eff↓, ROS↑, cl‑PARP↑, TumCCA↑, Casp8↑, Casp9↑, Casp3↑, eff↑, Bcl-2↑, Bcl-xL↓, survivin↓, MMP9↓, COX2/PTGS2↓, IAP1↓, Dose?,
7151- GI,    A novel shogaol analog suppresses cancer cell invasion and inflammation, and displays cytoprotective effects through modulation of NF-κB and Nrf2-Keap1 signaling pathways
- in-vitro, BC, MDA-MB-231 - in-vitro, BC, MCF7 - in-vitro, Nor, RAW264.7
MMP9↓, *NO↓, *iNOS↓, *COX2/PTGS2↓, *PGE2↓,
7260- Gink,    Ginkgetin: A natural biflavone with versatile pharmacological activities
- Review, Var, NA - Review, Stroke, NA - Review, AD, NA
*AntiCan↑, *Inflam↓, *AntiBio↑, *neuroP↑, *TumCCA↑, Apoptosis↑, TumAuto↑, iNOS↓, COX2/PTGS2↓, PGE2↓, NF-kB↓, PLA2↓, *neuroP↑, *Stroke↓, *AntiFungal↓, *Bacteria↓, Bcl-xL↓, Bcl-2↓, Casp9↑, Casp3↑, cl‑PARP↑, IL6↓, STAT3↓, JAK1↓, survivin↓, COX2/PTGS2↓, IAP1↓, MMP2↓, MMP9↓, PTEN↑, SHP1↑, Synergy↑, TumVol↓, TumW↓, *toxicity↓, *ROS↓,
7338- Gra,    Pharmacological Activities of Soursop (Annona muricata Lin.)
- Review, Var, NA
AntiCan↑, *AntiDiabetic↑, *Diar↓, *Bacteria↓, *AntiViral↑, *Wound Healing↑, MMP2↓, MMP9↓, MMP↓, ROS↑, TumCCA↑, BAX↑, Bcl-2↓, Casp3↑, *BAX↓, *MDA↓, *Catalase↑, *SOD↑, *GSH↑, *NO↑, *PGE2↑, *HSP70/HSPA5↑,
836- Gra,    Graviola: A Novel Promising Natural-Derived Drug That Inhibits Tumorigenicity and Metastasis of Pancreatic Cancer Cells In Vitro and In Vivo Through Altering Cell Metabolism
- vitro+vivo, PC, NA
Hif1a↓, NF-kB↓, GLUT1↓, GLUT4↓, HK2↓, LDHA↓, TumCCA↑, TumMeta↓, GlucoseCon↓, ATP↓, necrosis↑, Casp∅, p‑FAK↓, MMP9↓, MUC4↓,
1241- GSE,  PACs,    Grape seed proanthocyanidins inhibit angiogenesis via the downregulation of both vascular endothelial growth factor and angiopoietin signaling
- in-vitro, Nor, NA
*VEGF↓, *MMP2↓, *MMP9↓, *p‑VEGFR2/KDR/Flk1↓,
1118- GSE,    Grape Seed Proanthocyanidins Inhibit Migration and Invasion of Bladder Cancer Cells by Reversing EMT through Suppression of TGF- β Signaling Pathway
- in-vitro, Bladder, T24/HTB-9 - in-vitro, Bladder, 5637
TumCMig↓, TumCI↓, MMP2↓, MMP9↓, EMT↓, N-cadherin↓, Vim↓, Slug↓, E-cadherin↑, ZO-1↑, p‑SMAD2↓, p‑SMAD3↓, p‑Akt↓, p‑ERK↓, p‑p38↓,
1643- HCAs,    Mechanisms involved in the anticancer effects of sinapic acid
- Review, Var, NA
*BioAv↓, *toxicity↓, Dose∅, ROS⇅, ROS↑, Igs↑, TumCCA↑, TumAuto↑, eff↑, angioG↓, TumCI↓, TumMeta↓, EMT↓, Vim↓, MMP9↓, MMP2↓, Snail↓, E-cadherin↑, p‑Akt↓, GSK‐3β↓, TumCP↓, ChemoSen↑,
1649- HCAs,    Anticancer Properties of Hydroxycinnamic Acids -A Review
- Review, Var, NA
*antiOx↑, MMP2↓, MMP9↓, VEGF↓, TGF-β↓, Bax:Bcl2↑, TumCCA↑, COX2/PTGS2↓, NF-kB↓,
7365- HibSad,    Insight into the molecular evidence supporting the remarkable chemotherapeutic potential of Hibiscus sabdariffa L
- Review, Var, NA
chemoPv↑, selectivity↑, TumCCA↑, Apoptosis↑, TumAuto↑, TumMeta↓, ATG5↑, Beclin-1/ATG6↑, LC3II↑, MMP2↓, MMP9↓, CD31/PECAM-1↓, VEGF↓, uPA↓, TIMP2↑, NF-kB↓, p38↑, P53↑, Casp3↑, Casp8↑, Casp9↑, Bcl-2↓, BAX↑, Cyt‑c↑, TNF-α↑, Fas↑, FasL↑, JNK↑, cJun↑, angioG↓, VEGFR2/KDR/Flk1↓, PCNA↓, CCN2/CTGF↓, RAGE↓,
7354- HibSad,    Hibiscus sabdariffa Leaf Extract Inhibits Human Prostate Cancer Cell Invasion via Down-Regulation of Akt/NF-kB/MMP-9 Pathway
- vitro+vivo, Pca, LNCaP
MMP9↓, NF-kB↓, Akt↓, TumVol↓, PI3K↓, *antiOx↑, Dose↝,
1087- HNK,    Honokiol Inhibits Non-Small Cell Lung Cancer Cell Migration by Targeting PGE2-Mediated Activation of β-Catenin Signaling
- in-vitro, Lung, A549 - in-vitro, Lung, H1299 - in-vitro, Lung, H460 - in-vitro, Lung, H226
TumCMig↓, COX2/PTGS2↓, PGE2↓, NF-kB↓, p65↓, β-catenin/ZEB1↓, MMP2↓, MMP9↓,
2878- HNK,    Suppressing migration and invasion of H1299 lung cancer cells by honokiol through disrupting expression of an HDAC6-mediated matrix metalloproteinase 9
- in-vitro, Lung, H1299
TumCMig↓, TumCI↓, MMP9↓, α-tubulin↑, HDAC6↓, HSP90↓,
2874- HNK,    Suppressing migration and invasion of H1299 lung cancer cells by honokiol through disrupting expression of an HDAC6‐mediated matrix metalloproteinase 9
- in-vitro, Lung, H1299
MMP9↓, α-tubulin↑, TumCI↓, HDAC6↓, HSP90↓, TumCMig↓, EGFR↓,
2891- HNK,    Honokiol, an Active Compound of Magnolia Plant, Inhibits Growth, and Progression of Cancers of Different Organs
- Review, Var, NA
AntiCan↑, Inflam↓, antiOx↑, selectivity↑, *toxicity↓, cycD1/CCND1↓, cycE/CCNE↓, CDK2↓, CDK4↓, TumMeta↓, NADPH↓, MMP2↓, MMP9↓, p‑mTOR↓, EGFR↓, EMT↓, SIRT1↑, SIRT3↑, EZH2↓, Snail↓, Vim↓, N-cadherin↓, E-cadherin↑, COX2/PTGS2↓, NF-kB↓, *ROS↓, Ca+2↑, ROS↑,
2897- HNK,    Honokiol Inhibits Proliferation, Invasion and Induces Apoptosis Through Targeting Lyn Kinase in Human Lung Adenocarcinoma Cells
- in-vitro, Lung, PC9 - in-vitro, Lung, A549
TumCP↓, Apoptosis↑, EGFR↓, PI3K↓, Akt↓, STAT3↓, TumCI↓, TNF-α↑, NF-kB↓, VEGF↓, MMP9↓, COX2/PTGS2↓,
2898- HNK,    Honokiol Suppression of Human Epidermal Growth Factor Receptor 2 (HER2)-Positive Gastric Cancer Cell Biological Activity and Its Mechanism
- in-vitro, GC, AGS - in-vitro, GC, NCI-N87 - in-vitro, BC, MGC803 - in-vitro, GC, SGC-7901
TumCP↓, Apoptosis↑, TumCI↓, TumCMig↓, HER2/EBBR2↓, TumCCA↑, PI3K↓, Akt↓, MMP9↓, P21↑,
7469- Hops,    CHEMOPREVENTIVE PROPERTIES OF SPENT HOPS (HUMULUS LUPULUS L.) EXTRACT AGAINST ANGIOGENESIS, INVASION AND MIGRATION OF COLORECTAL CANCER CELLS
- in-vitro, CRC, SW48 - in-vitro, CRC, HT29
angioG↓, TumCI↓, TumCMig↓, MMP2↓, MMP9↓, VEGF↓, Hif1a↓, chemoPv↑,

Showing Research Papers: 201 to 250 of 448
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* indicates research on normal cells as opposed to diseased cells
Total Research Paper Matches: 448

Pathway results for Effect on Cancer / Diseased Cells:


NA, unassigned(tgid=0) ⓘ

NA↓, 1,  

Redox & Oxidative Stress(tgid=1) ⓘ

antiOx↓, 3,   antiOx↑, 10,   antiOx⇅, 1,   Catalase↓, 5,   Catalase↑, 3,   Copper↓, 1,   Copper↑, 1,   frataxin↑, 1,   GPx↓, 2,   GPx↑, 4,   GPx4↓, 6,   GSH↓, 23,   GSH↑, 5,   GSR↑, 2,   GSTs↓, 1,   GSTs↑, 2,   H2O2↓, 1,   H2O2↑, 5,   HO-1↓, 9,   HO-1↑, 14,   HO-2↓, 1,   Iron↑, 3,   Keap1↓, 1,   lipid-P?, 1,   lipid-P↓, 4,   lipid-P↑, 13,   MDA↓, 5,   MDA↑, 5,   MPO↓, 1,   NOX4↓, 1,   NQO1↓, 1,   NQO1↑, 3,   NRF2↓, 13,   NRF2↑, 16,   NRF2⇅, 1,   NRF2↝, 1,   p‑NRF2↓, 1,   Prx↓, 1,   Prx4↑, 1,   PrxII↓, 1,   RNS↑, 1,   ROS?, 2,   ROS↓, 26,   ROS↑, 170,   ROS⇅, 7,   ROS∅, 1,   i-ROS↓, 2,   i-ROS↑, 2,   mt-ROS↑, 1,   SOD↓, 6,   SOD↑, 7,   SOD1↓, 1,   SOD1↑, 2,   SOD2↓, 1,   SOD2↑, 3,   TBARS↑, 1,   Thiols↓, 1,   Trx1↑, 1,   TrxR↓, 7,   xCT/SLC7A11↓, 1,  

Metal & Cofactor Biology(tgid=2) ⓘ

Ferritin↓, 1,   IronCh↑, 2,   Tf↓, 1,   TfR1/CD71↓, 1,  

Mitochondria & Bioenergetics(tgid=3) ⓘ

ADP:ATP↑, 2,   Bfl-1↓, 1,   CDC2↓, 7,   CDC25↓, 10,   compI↓, 1,   compIII↓, 1,   compV↓, 1,   EGF↓, 5,   ETC↓, 3,   mitResp↓, 1,   mitResp↑, 1,   MKK7↓, 1,   mtDam↑, 8,   OCR↓, 3,   mt-OXPHOS↓, 1,   PDH↝, 1,   PINK1↑, 1,   SIRT3↓, 2,   SIRT3↑, 3,  

Core Metabolism/Glycolysis(tgid=4) ⓘ

12LOX↓, 3,   5LO↓, 6,   ACADS/SCAD↓, 1,   ACC↑, 1,   ALAT↓, 6,   ALAT↝, 1,   AMPK↓, 2,   AMPK↑, 20,   AMPK↝, 1,   p‑AMPK↑, 2,   p‑AMT/GCST/T-protein↑, 1,   ATP↓, 13,   mt-ATP↓, 1,   CAIX/CA9↑, 1,   ECAR↓, 1,   ECAR↝, 1,   ENO1↓, 1,   FABP4↑, 1,   FASN↓, 3,   FASN↑, 1,   GAPDH↓, 2,   GLO-I↓, 1,   glucoNG↓, 1,   glucose↓, 1,   GlucoseCon↓, 9,   GlutMet↓, 2,   Glycolysis↓, 23,   GSK‐3β↓, 11,   GSK‐3β↑, 2,   p‑GSK‐3β↓, 3,   HK1↓, 1,   HK2↓, 11,   lactateProd↓, 9,   LDHA↓, 6,   LDL↓, 1,   lipidLev↓, 1,   NADPH↓, 3,   NADPH↑, 3,   O-Glc↓, 1,   PDK1 / PDPK1?, 2,   PDK1 / PDPK1↓, 7,   p‑PDK1 / PDPK1↓, 1,   PDK3↑, 1,   PFK↓, 1,   PIP3↑, 1,   PKM2↓, 8,   PKM2↑, 1,   PLA2↓, 1,   p‑S6↓, 1,   SIRT1↓, 6,   SIRT1↑, 9,   SIRT2↑, 1,   SREBP1/SREBF1↓, 2,   SREBP2↓, 1,   Warburg↓, 4,  

Cell Death(tgid=5) ⓘ

AIF↑, 10,   APAF1↑, 4,   Apoptosis?, 1,   Apoptosis↓, 4,   Apoptosis↑, 143,   ASC↑, 1,   ASK1↑, 1,   BAD↓, 3,   BAD↑, 5,   Bak↑, 5,   BAX↓, 2,   BAX↑, 94,   BAX⇅, 1,   BAX↝, 1,   Bax:Bcl2↑, 22,   Bcl-2↓, 104,   Bcl-2↑, 3,   Bcl-xL↓, 35,   BID↓, 2,   BID↑, 6,   p‑BID↓, 1,   BIM↑, 5,   BNIP3↑, 3,   BNIP3↝, 1,   Casp↓, 1,   Casp↑, 25,   Casp∅, 1,   cl‑Casp↑, 1,   Casp1↓, 1,   Casp1↑, 1,   Casp12?, 1,   Casp12↑, 2,   Casp2↑, 1,   Casp3↓, 5,   Casp3↑, 114,   Casp3∅, 1,   cl‑Casp3↑, 15,   proCasp3↑, 1,   Casp6↑, 1,   Casp7↑, 12,   cl‑Casp7↑, 1,   Casp8↑, 29,   Casp8∅, 1,   cl‑Casp8↑, 4,   proCasp8↑, 2,   Casp9↓, 1,   Casp9↑, 76,   p‑Casp9↑, 1,   cl‑Casp9↑, 8,   proCasp9↓, 1,   proCasp9↑, 1,   cFLIP↓, 4,   Cyt‑c↓, 1,   Cyt‑c↑, 62,   mt-Cyt‑c↓, 1,   Diablo↑, 12,   DR5↑, 22,   Endon↑, 2,   FADD↑, 4,   Fap1↓, 1,   Fas↓, 1,   Fas↑, 20,   FasL↓, 1,   FasL↑, 8,   FasL⇅, 1,   Ferroptosis↑, 7,   GranB/GZMB↝, 1,   GSDME↑, 1,   HEY1↓, 2,   IAP1↓, 16,   IAP2/BIRC3↓, 6,   ICAD↓, 1,   ICD↑, 1,   iNOS↓, 19,   Mcl-1?, 1,   Mcl-1↓, 27,   p‑Mcl-1↓, 1,   MDM2↓, 9,   MDM2↑, 1,   MOMP↑, 2,   Necroptosis↑, 1,   necrosis↑, 2,   NOXA↑, 3,   p38↓, 13,   p38↑, 13,   p‑p38↓, 4,   p‑p38↑, 4,   p‑p38↝, 1,   Perforin↝, 1,   PUMA↓, 1,   PUMA↑, 6,   Pyro↑, 4,   RIP1↑, 1,   RIP3↑, 1,   survivin↓, 53,   TNFR 1↑, 1,   TRAIL↑, 3,   TRAILR↑, 2,   TumCD↓, 1,   TumCD↑, 7,   XIAP↓, 26,   XIAP↑, 1,   YAP/TEAD↓, 5,  

Kinase & Signal Transduction(tgid=6) ⓘ

Akt↓, 134,   Akt↑, 4,   p‑Akt↓, 43,   AKT1↓, 2,   Akt2↓, 1,   CaMKII ↓, 1,   CIP2A↓, 2,   CK2↓, 4,   cMET↓, 2,   p‑cMET↓, 1,   cSrc↓, 3,   EGFR↓, 34,   p‑EGFR↓, 3,   ERK↓, 53,   ERK↑, 8,   p‑ERK↓, 23,   p‑ERK↑, 1,   p‑ERK↝, 1,   FGFR1↓, 3,   FGFR2↓, 1,   FOXD3↑, 2,   HER2/EBBR2↓, 13,   p‑HER2/EBBR2↓, 1,   HGF/c-Met↓, 2,   Hippo↑, 1,   IGF-1R↓, 6,   IGFR↓, 1,   IKKα↓, 10,   IKKα↝, 1,   p‑IKKα↓, 2,   IκB↓, 1,   p‑IκB↓, 3,   p‑IκB↑, 1,   JAK↓, 6,   p‑JAK↓, 1,   JAK1↓, 4,   p‑JAK1↓, 1,   JAK2↓, 17,   p‑JAK2↓, 3,   p‑JAK3↓, 1,   JNK↓, 12,   JNK↑, 18,   p‑JNK↓, 5,   p‑JNK↑, 2,   p‑JNK↝, 1,   p‑MAP2K1/MEK1↓, 1,   MAPK↓, 35,   MAPK↑, 13,   p‑MAPK↓, 2,   MARK4↓, 2,   MEK↓, 5,   p‑MEK↓, 2,   MKK4↓, 1,   mTOR↓, 67,   mTOR↝, 1,   p‑mTOR↓, 11,   mTORC2↓, 2,   mTORC2↑, 1,   p70S6↓, 1,   P70S6K↓, 2,   p‑P70S6K↓, 1,   p‑P90RSK↑, 1,   PDGFR-BB↓, 1,   p‑PDGFR-BB↓, 1,   PDGFRA↓, 1,   PI3K↓, 106,   PI3K↑, 1,   p‑PI3K↓, 8,   p‑PI3K↑, 1,   PI3K/Akt↓, 4,   PKA↓, 2,   PKCδ↓, 14,   p‑PKCδ↓, 1,   PTEN↓, 1,   PTEN↑, 29,   Raf↓, 5,   e-Raf↓, 1,   c-Raf↓, 1,   RAS↓, 12,   p‑S6K↓, 1,   SHP1↑, 2,   Sp1/3/4↓, 12,   Sp1/3/4↑, 1,   Src↓, 2,   p‑Src↓, 1,   STAT↓, 4,   p‑STAT2↓, 1,   STAT3↓, 76,   STAT3↑, 3,   p‑STAT3↓, 13,   p‑STAT3↑, 3,   STAT5↓, 3,   STAT6↓, 2,   TSC2↑, 1,  

Transcription & Epigenetics(tgid=7) ⓘ

ATF3↑, 1,   ATF4↓, 1,   ATF4↑, 6,   ATF4↝, 1,   CBP↓, 1,   cJun↓, 8,   cJun↑, 1,   p‑cJun↓, 1,   cMyc↓, 40,   cMyc↑, 1,   p‑cMyc↑, 1,   DNMT1↓, 6,   DNMTs↓, 7,   EZH2↓, 6,   FOXM1↓, 4,   FOXO↑, 3,   FOXO1↓, 3,   FOXO1↑, 1,   FOXO3↓, 3,   FOXO3↑, 8,   FOXO3↝, 1,   p‑FOXO3↓, 1,   FOXO4↓, 2,   FOXO4↑, 1,   H3↑, 1,   ac‑H3↓, 1,   ac‑H3↑, 2,   H4↑, 1,   ac‑H4↓, 1,   ac‑H4↑, 2,   HATs↓, 7,   HATs↑, 1,   HDAC↓, 18,   HDAC1↓, 5,   HDAC10↓, 1,   HDAC2↓, 3,   HDAC3↓, 2,   HDAC4↓, 1,   HDAC6↓, 2,   HDAC8↓, 1,   HES1↓, 3,   JPT1/HN1↓, 1,   LINC01116↓, 1,   Matr↓, 1,   miR-106b↓, 1,   miR-107↑, 2,   miR-10b-5p↓, 1,   miR-126↓, 1,   miR-133a-3p↑, 1,   miR-139-5p↑, 2,   miR-149↑, 1,   miR-155↓, 5,   miR-155↑, 1,   miR-17↓, 1,   miR-182-5p↓, 1,   miR-194↑, 1,   miR-195↑, 1,   miR-200b↑, 2,   miR-200c↓, 1,   miR-203↑, 1,   miR-21↓, 8,   miR-21↑, 2,   miR-210↑, 1,   miR-221↓, 1,   miR-224↓, 2,   miR-25-5p↑, 1,   miR-27a-3p↓, 1,   miR-27a-3p↑, 1,   miR-301a-3p↓, 1,   miR-340↓, 2,   miR-34a↑, 5,   miR-34b-5p↑, 1,   miR-384↑, 2,   miR-422a↑, 2,   miR-592↑, 1,   MTA2↓, 1,   Myc↓, 5,   n-MYC↓, 2,   NDRG1↑, 1,   OCT4↓, 15,   other↓, 3,   other↑, 1,   other↝, 4,   other∅, 1,   PAX2↓, 1,   PhotoS↑, 1,   SOX2↓, 11,   SOX4↓, 2,   SOX4↑, 1,   SOX9?, 1,   SOX9↓, 2,   SOX9↑, 1,   TCF-4↓, 2,   tumCV↓, 28,   ZBTB10↑, 1,  

Protein Folding & ER Stress(tgid=8) ⓘ

ATF6↑, 1,   CHOP/DDIT3↓, 1,   CHOP/DDIT3↑, 17,   eIF2α↓, 1,   p‑eIF2α↑, 3,   ER Stress↓, 1,   ER Stress↑, 33,   Erlin1↑, 1,   GRP78/BiP↓, 2,   GRP78/BiP↑, 12,   GRP78/BiP↝, 1,   HSF1↓, 1,   HSP27↓, 4,   HSP27↝, 1,   HSP70/HSPA5↓, 7,   HSP70/HSPA5↑, 1,   HSP70/HSPA5↝, 1,   HSP90↓, 11,   HSPs↓, 1,   IRE1↑, 5,   PDI↑, 1,   PERK↑, 3,   Proteasome↓, 1,   SERPINH1/HSP47↓, 1,   UPR↓, 1,   UPR↑, 4,   XBP-1↓, 1,   XBP-1↑, 1,  

Autophagy & Lysosomes(tgid=9) ⓘ

ATG5↓, 1,   ATG5↑, 2,   ATG7↑, 1,   Beclin-1/ATG6↓, 5,   Beclin-1/ATG6↑, 10,   CTSB↓, 2,   CTSD↓, 2,   CTSK↓, 1,   LC3‑Ⅱ/LC3‑Ⅰ↓, 1,   LC3A↑, 1,   LC3B↓, 1,   LC3B-II↓, 1,   LC3B-II↑, 4,   LC3II↓, 3,   LC3II↑, 8,   LC3s↓, 1,   LC3s↑, 1,   p62↓, 6,   p62↑, 2,   PARK2↑, 1,   TumAuto↓, 1,   TumAuto↑, 31,   TumAuto⇅, 1,  

DNA Damage & Repair(tgid=10) ⓘ

ATM?, 1,   ATM↑, 2,   BRCA1↓, 1,   BRCA1↑, 1,   p‑BRCA1↑, 1,   BRCA2↑, 1,   DFF45↓, 2,   DNAdam↓, 3,   DNAdam↑, 40,   DNArepair↓, 2,   DNArepair↑, 1,   ERCC1↓, 1,   ERCC3↑, 1,   hTERT/TERT↓, 11,   MGMT↓, 1,   p16↑, 4,   P53?, 2,   P53↓, 2,   P53↑, 75,   P53↝, 1,   p‑P53↑, 1,   PARP↓, 2,   PARP↑, 16,   cl‑PARP↓, 1,   cl‑PARP↑, 50,   PARP1↑, 1,   PCNA↓, 24,   POLD1↓, 1,   SIRT6↓, 2,   SIRT6↑, 1,   Telomerase↓, 14,   TOP1↓, 7,   TOP2↓, 6,   TOP2↑, 2,   TP53↑, 3,   TRF2↓, 1,   UHRF1↓, 1,   XRCC1↓, 1,   γH2AX↓, 1,   γH2AX↑, 8,   γH2AX↝, 1,  

Cell Cycle & Senescence(tgid=11) ⓘ

CC(CDKs/cyclins)↓, 1,   CDK1↓, 11,   p‑CDK1↓, 1,   CDK1/2/5/9↓, 1,   CDK2↓, 40,   CDK2↑, 3,   CDK4↓, 51,   CDK4↑, 1,   p‑CDK4↓, 1,   CDK4/6↓, 1,   CDK6↓, 24,   CDK6↑, 1,   CDK8↓, 1,   CDKN1C/p57↓, 1,   CDKN1C/p57↑, 1,   CHK1↓, 3,   p‑CHK1↑, 1,   Chk2↓, 2,   Cyc↓, 2,   cycA1/CCNA1↓, 9,   cycA1/CCNA1↑, 2,   CycB/CCNB1↓, 19,   CycB/CCNB1↑, 1,   cycD1/CCND1↓, 85,   cycD1/CCND1↑, 1,   p‑cycD1/CCND1↓, 1,   CycD3↓, 3,   cycE/CCNE↓, 23,   E2Fs↓, 5,   GADD45A↑, 1,   Ki-67↓, 28,   MAD↓, 1,   P21↓, 4,   P21↑, 55,   p27/CDKN1B↓, 2,   p27/CDKN1B↑, 21,   pRB↓, 2,   pRB↑, 1,   p‑pRB↓, 1,   RB1↓, 1,   RB1↑, 2,   p‑RB1↓, 5,   Securin↓, 1,   TumCCA?, 1,   TumCCA↓, 10,   TumCCA↑, 148,  

Proliferation, Differentiation & Cell State(tgid=12) ⓘ

4E-BP1↓, 1,   ALDH↓, 6,   ALDH1A1↓, 3,   BMP2↓, 2,   BMPs↑, 1,   CD133↓, 10,   CD133↑, 1,   CD24↓, 4,   CD34↓, 1,   cFos↓, 8,   p‑cFos↓, 1,   cMYB↓, 1,   CSCs↓, 38,   CSCs↑, 1,   Diff↓, 1,   Diff↑, 3,   EIF4E↓, 1,   FGF↓, 3,   FGF↑, 1,   Gli↓, 2,   Gli1↓, 9,   HH↓, 8,   IGF-1↓, 9,   IGF-2↓, 1,   IGFBP3↓, 1,   IGFBP3↑, 2,   JAG1↓, 1,   Jun↓, 1,   Ki-67↓, 28,   Let-7↑, 6,   LRP6↓, 1,   p‑LRP6↓, 1,   mTORC1↓, 4,   p‑mTORC1↓, 1,   Nanog↓, 11,   Nestin↓, 2,   NICD↓, 1,   NOTCH↓, 19,   NOTCH1↓, 12,   NOTCH1↑, 3,   NOTCH1↝, 1,   NOTCH2↓, 1,   NOTCH3↓, 2,   p300↓, 2,   Piezo1↑, 1,   PTCH1↓, 2,   Shh↓, 7,   Smo↓, 3,   STAT1↓, 1,   p‑STAT1↓, 1,   Sufu↓, 1,   TAZ↓, 1,   TOPflash↓, 1,   TumCG↓, 67,   TumCG↑, 2,   TumCP?, 1,   TumCP↓, 127,   TumCP↑, 2,   tyrosinase↓, 2,   URGCP/URG4↓, 1,   Wnt↓, 42,   Wnt/(β-catenin)↓, 5,   ZFX↓, 1,  

Migration(tgid=13) ⓘ

AEG1↓, 1,   AntiAg?, 1,   AntiAg↓, 1,   AntiAg↑, 2,   AP-1↓, 20,   AP-1↝, 1,   ATPase↓, 1,   AXL↓, 2,   CA↓, 3,   Ca+2↓, 1,   Ca+2↑, 32,   Ca+2↝, 1,   i-Ca+2?, 1,   i-Ca+2↑, 1,   CAFs/TAFs↓, 2,   cal2↓, 1,   CCN2/CTGF↓, 2,   Cdc42↑, 1,   Cofilin↓, 1,   COL1A1↓, 1,   COL3A1↓, 1,   DLC1↑, 1,   E-cadherin↓, 13,   E-cadherin↑, 69,   EMMPRIN↓, 1,   EMT↓, 101,   EMT↑, 3,   EpCAM↓, 4,   F-actin↓, 2,   FAK↓, 22,   FAK↑, 2,   p‑FAK↓, 5,   fascin↓, 1,   Fibronectin↓, 8,   GIT1↓, 1,   GLI2↓, 2,   IQGAP3↓, 1,   ITGA1∅, 1,   ITGA5↓, 3,   ITGA5∅, 1,   ITGB1↓, 4,   ITGB1∅, 1,   ITGB3↓, 1,   ITGB3∅, 1,   ITGB4∅, 1,   KAI1/CD82↑, 1,   LAMs↓, 1,   LIMK2↓, 1,   MALAT1↓, 1,   MET↓, 1,   MMP-10↓, 2,   MMP1↓, 13,   MMP11↓, 1,   MMP13↓, 8,   MMP14↓, 1,   MMP16↓, 3,   MMP2?, 2,   MMP2↓, 260,   MMP2↑, 2,   MMP2⇅, 1,   MMP2↝, 1,   MMP2∅, 1,   MMP3↓, 15,   MMP7↓, 16,   MMP7∅, 1,   MMP9?, 2,   MMP9↓, 399,   MMP9↑, 9,   MMP9⇅, 1,   MMP9↝, 1,   MMP9∅, 1,   pro‑MMP9↓, 1,   MMPs↓, 27,   MTA1↓, 1,   MUC4↓, 2,   N-cadherin↓, 46,   NCAM↓, 1,   PAI-1/SERPINE1↓, 1,   PAK1↓, 2,   PDGF↓, 7,   Rac1↓, 1,   RECK↑, 1,   Rho↓, 6,   ROCK1↓, 7,   ROCK1↑, 1,   Sharpin↓, 1,   Slug?, 1,   Slug↓, 20,   Smad1↓, 1,   Smad1↑, 1,   SMAD2↓, 1,   p‑SMAD2↓, 2,   SMAD3↓, 2,   SMAD3↑, 1,   p‑SMAD3↓, 2,   SMAD4↓, 2,   Snail?, 2,   Snail↓, 37,   Snail↑, 1,   STAC2↓, 1,   TET1↓, 1,   TET1↑, 3,   TGF-β↓, 21,   TGF-β↑, 2,   TGF-β1↓, 1,   TIMP1↓, 7,   TIMP1↑, 23,   TIMP2↓, 5,   TIMP2↑, 17,   TIMP3↑, 2,   TSP-1↑, 3,   TumCA↓, 7,   TumCA↑, 1,   TumCI↓, 135,   TumCI↑, 2,   TumCMig↓, 126,   TumCMig↑, 1,   TumMeta↓, 94,   TumMeta↑, 6,   TumPF↓, 1,   Twist↓, 28,   Twist↑, 1,   uPA↓, 40,   uPAR↓, 7,   Vim?, 1,   Vim↓, 59,   Zeb1↓, 18,   ZEB2↓, 3,   ZEB2↑, 1,   α-SMA↓, 4,   α-SMA↑, 1,   α-tubulin↑, 3,   β-catenin/ZEB1↓, 49,   β-catenin/ZEB1↑, 1,  

Angiogenesis & Vasculature(tgid=14) ⓘ

angioG↓, 97,   angioG↑, 1,   angioS↑, 1,   CCN1/CYR61↓, 1,   CD31/PECAM-1↓, 3,   ECM/TCF↓, 1,   Endoglin↑, 1,   eNOS↓, 3,   HIF-1↓, 4,   Hif1a↓, 57,   Hif1a↑, 2,   Hif1a↝, 1,   LOX1↓, 1,   NO↓, 7,   NO↑, 1,   PHDs↓, 1,   TXA2↓, 1,   VCAM-1↓, 4,   VEGF↓, 148,   VEGF↑, 1,   VEGFR1↓, 5,   VEGFR2/KDR/Flk1↓, 19,  

Barriers & Transport(tgid=15) ⓘ

BBB↑, 4,   BBB∅, 1,   CLDN1↓, 2,   CLDN2↓, 1,   EPR↑, 5,   EPR↝, 1,   GLUT1↓, 9,   GLUT1↑, 1,   GLUT3↑, 1,   GLUT4↓, 1,   MMP↓, 75,   MMP↑, 1,   MMP∅, 1,   MPT↑, 5,   NHE1↓, 2,   TRPM7↓, 1,   TRPV1↑, 3,   ZO-1↑, 4,  

Immune & Inflammatory Signaling(tgid=16) ⓘ

CCR7↓, 1,   CD4+↓, 1,   CD4+↑, 1,   CD44↓, 15,   CD8+↑, 1,   p‑cDC2↓, 1,   COX1↓, 5,   COX2/PTGS2↓, 107,   COX2/PTGS2↑, 2,   COX2/PTGS2↝, 1,   CXCL1↓, 1,   CXCL12↓, 2,   CXCL16↓, 1,   CXCR2↓, 2,   CXCR4↓, 23,   CXCR4↑, 1,   DR4↑, 8,   FOXP3↓, 2,   FOXP3↑, 1,   Gal-3↓, 1,   HMGB1↓, 4,   ICAM-1↓, 12,   IFN-γ↓, 2,   IFN-γ↑, 2,   Igs↑, 1,   IL-1Ra↑, 1,   IL1↓, 7,   IL1↑, 2,   IL10↓, 6,   IL10↑, 3,   IL12↓, 4,   IL12↑, 1,   IL17↓, 1,   IL18↓, 2,   IL18↑, 1,   IL1R2↑, 1,   IL1RL1/ST2↑, 1,   IL1α↓, 2,   IL1β↓, 15,   IL1β↑, 2,   IL2↓, 4,   IL2↑, 4,   IL22↓, 1,   IL23↓, 1,   IL33↑, 1,   IL4↓, 2,   IL4↑, 2,   IL6↓, 53,   IL6↑, 1,   IL8↓, 13,   IL8↑, 2,   Imm↑, 2,   Imm↝, 3,   Inflam↓, 27,   IRAK1↓, 1,   M2 MC↓, 2,   MCP1/CCL2↓, 7,   MIP2↓, 1,   mPGES-1↓, 2,   NF-kB?, 1,   NF-kB↓, 168,   NF-kB↑, 1,   NF-kB↝, 1,   p‑NF-kB↓, 2,   p‑NF-kB↑, 1,   NK cell↑, 3,   NLRP3↓, 3,   NLRP3↑, 2,   p50↓, 3,   p65↓, 11,   p65↑, 1,   p‑p65↓, 3,   PD-1↓, 2,   PD-L1↓, 8,   PD-L1↑, 1,   PGE2↓, 25,   PSA↓, 5,   PSA∅, 1,   RAGE↓, 1,   T-Cell↑, 1,   Th1 response↑, 2,   TLR2↓, 1,   TLR4↓, 3,   TLR4↝, 1,   TNF-α↓, 34,   TNF-α↑, 7,   TNF-α∅, 1,   TNFRSF25/DR3/APO3/LARD/TRAMP/WSL1↑, 1,   TRAF1↓, 1,   Treg lymp↓, 1,  

Cellular Microenvironment(tgid=17) ⓘ

TAMS↝, 1,  

Synaptic & Neurotransmission(tgid=18) ⓘ

5HT↓, 1,   PTN↓, 1,  

Protein Aggregation(tgid=19) ⓘ

XO↓, 1,  

Hormonal & Nuclear Receptors(tgid=20) ⓘ

AhR↓, 1,   AhR↑, 1,   AhR↓, 1,   AR↓, 12,   AR↑, 1,   CYP19↓, 1,   ER-α36↓, 2,   ER(estro)↓, 1,   ERα/ESR1↓, 1,   FGF21↓, 1,   GR↑, 1,   PPARα↓, 2,   PPARα↑, 1,   PPARα↝, 1,   cl‑PPARα↓, 1,   PPARγ↓, 3,   PPARγ↑, 8,   RANKL↓, 2,  

Drug Metabolism & Resistance(tgid=21) ⓘ

BioAv↓, 40,   BioAv↑, 41,   BioAv↝, 10,   BioEnh↑, 2,   CBR1↓, 1,   ChemoSen↓, 2,   ChemoSen↑, 122,   CompStab↓, 1,   CompStab↝, 2,   CYP1A1↓, 3,   CYP1A1↑, 2,   CYP1A2↓, 1,   CYP1B1↑, 1,   DDS↑, 1,   Dose?, 3,   Dose↓, 3,   Dose↑, 6,   Dose↝, 36,   Dose∅, 9,   eff?, 1,   eff↓, 17,   eff↑, 62,   eff↝, 10,   GSTA1↑, 1,   Half-Life↓, 9,   Half-Life↑, 4,   Half-Life↝, 9,   Half-Life∅, 1,   MDR1↓, 7,   MRP1/ABCC1↓, 3,   MRP1/ABCC1↝, 1,   P-gp/ABCB1↓, 17,   P-gp/ABCB1⇅, 1,   P450↓, 1,   RadioS↑, 37,   selectivity?, 2,   selectivity↑, 45,   selectivity∅, 1,   Synergy↑, 88,   TET2↑, 1,  

Clinical Biomarkers(tgid=22) ⓘ

AFP↓, 1,   ALAT↓, 6,   ALAT↝, 1,   ALP↓, 2,   ALP↝, 1,   AR↓, 12,   AR↑, 1,   ascitic↓, 2,   AST↓, 4,   AST↝, 1,   BRCA1↓, 1,   BRCA1↑, 1,   p‑BRCA1↑, 1,   CA125↓, 1,   CRP↓, 3,   E6↓, 2,   E7↓, 2,   EGFR↓, 34,   p‑EGFR↓, 3,   ERα/ESR1↓, 1,   EZH2↓, 6,   Ferritin↓, 1,   FOXM1↓, 4,   HER2/EBBR2↓, 13,   p‑HER2/EBBR2↓, 1,   hTERT/TERT↓, 11,   IL6↓, 53,   IL6↑, 1,   LDH↓, 3,   LDH↑, 4,   Myc↓, 5,   PD-L1↓, 8,   PD-L1↑, 1,   PSA↓, 5,   PSA∅, 1,   RAGE↓, 1,   TP53↑, 3,  

Functional Outcomes(tgid=23) ⓘ

AntiCan↑, 40,   AntiCan?, 1,   antiCG↓, 1,   antiD↑, 1,   AntiDiabetic↑, 2,   antiNeop↑, 3,   AntiTum↓, 1,   AntiTum↑, 19,   cachexia↓, 2,   cardioP↑, 8,   CardioT↑, 2,   chemoP?, 1,   chemoP↑, 16,   chemoPv↑, 18,   ChemoSideEff↓, 4,   cognitive↑, 2,   hepatoP↓, 1,   hepatoP↑, 8,   neuroP↑, 5,   OS↑, 7,   Pin1↓, 1,   QoL↑, 2,   radioP↑, 7,   Remission↑, 1,   RenoP↑, 5,   Risk↓, 4,   toxicity↓, 13,   toxicity↑, 5,   toxicity↝, 6,   toxicity∅, 1,   TumVol↓, 16,   TumVol∅, 1,   TumW↓, 5,   TumW∅, 1,   Weight↑, 1,   Weight∅, 1,   Wound Healing↓, 1,  

Infection & Microbiome(tgid=24) ⓘ

Bacteria↓, 1,   GutMicro↑, 3,   GutMicro↝, 1,   Sepsis↓, 3,  

Ingredients & Constituents(tgid=25) ⓘ

Ingr↝, 1,  
Total Targets: 1037

Pathway results for Effect on Normal Cells:


Redox & Oxidative Stress(tgid=1) ⓘ

antiOx↓, 5,   antiOx↑, 77,   ARE↑, 1,   Catalase↑, 31,   Copper↓, 1,   GPx↓, 1,   GPx↑, 25,   GPx1↑, 1,   GPx3↑, 1,   GPx4↑, 1,   GSH↑, 28,   GSR↓, 1,   GSR↑, 6,   GSTs↑, 11,   H2O2↓, 5,   H2O2∅, 1,   HDL↓, 1,   HDL↑, 2,   HO-1↑, 20,   hyperG↝, 1,   Iron↓, 2,   i-Iron↓, 1,   Keap1↓, 1,   lipid-P↓, 18,   mt-lipid-P↓, 1,   MDA↓, 22,   MPO↓, 3,   MPO↑, 1,   NADH↓, 1,   NQO1↑, 3,   Nrf1↑, 1,   NRF2?, 1,   NRF2↑, 30,   Prx↑, 2,   RNS↓, 4,   ROS?, 2,   ROS↓, 86,   SOD↑, 40,   SOD1↑, 6,   SOD2↑, 3,   TAC↑, 1,   TrxR↑, 1,   xCT/SLC7A11↑, 1,  

Metal & Cofactor Biology(tgid=2) ⓘ

IronCh↑, 4,   Mets↝, 1,  

Mitochondria & Bioenergetics(tgid=3) ⓘ

Insulin↑, 1,   mtDam↓, 1,   PGC-1α↓, 1,   PGC-1α↑, 1,  

Core Metabolism/Glycolysis(tgid=4) ⓘ

12LOX↑, 1,   5LO↓, 3,   ALAT↓, 8,   AMPK↑, 8,   ATP↑, 1,   cAMP↑, 1,   DGAT1↓, 1,   FASN↓, 1,   glucose↓, 1,   glucose↑, 1,   GlucoseCon↑, 2,   GlutMet↑, 1,   GSK‐3β↓, 4,   GSK‐3β↑, 1,   LDL↓, 3,   NAD↑, 1,   NADH:NAD↑, 1,   SIRT1↑, 11,  

Cell Death(tgid=5) ⓘ

Apoptosis↓, 4,   ASC?, 1,   BAD↓, 1,   BAX↓, 7,   Bcl-2↓, 1,   Bcl-2↑, 1,   Bcl-xL↑, 1,   Casp1↓, 1,   Casp3?, 1,   Casp3↓, 7,   Casp3∅, 1,   cl‑Casp3↓, 1,   cl‑Casp8↓, 1,   Casp9↓, 2,   Cyt‑c↓, 3,   Cyt‑c∅, 2,   Ferroptosis↓, 1,   iNOS↓, 14,   iNOS↑, 1,   necrosis↓, 1,   p38↓, 1,   p38↑, 2,   Pyro?, 1,   RIP1↓, 1,  

Kinase & Signal Transduction(tgid=6) ⓘ

Akt↓, 1,   Akt↑, 5,   p‑Akt↓, 2,   p‑Akt↑, 2,   AKT1↓, 1,   CREB↑, 1,   p‑CREB↑, 1,   ERK↓, 1,   ERK↑, 4,   p‑ERK↑, 1,   IGF-1R↓, 1,   JAK↓, 1,   JAK2↑, 1,   JNK↓, 3,   JNK↑, 1,   p‑JNK↓, 1,   p‑LIMK1↑, 1,   MAPK↓, 9,   MAPK↑, 4,   mTOR↓, 1,   mTOR↑, 2,   PDGFR-BB↓, 1,   PI3K↓, 1,   PI3K↑, 5,   PKA↑, 1,   PKCδ↑, 3,   PP2A↑, 1,   PTEN↓, 2,   PTEN↑, 1,   Src↓, 1,   STAT↓, 1,   STAT3↓, 4,   STAT3↑, 2,   p‑STAT3↑, 1,  

Transcription & Epigenetics(tgid=7) ⓘ

AntiThr↑, 3,   cJun↓, 1,   cMyc↓, 1,   p‑cMyc↑, 1,   FOXO↑, 1,   HDAC↓, 1,   HOTAIR↑, 1,   other↓, 4,   other↑, 5,   other↝, 7,   RUNX2↑, 1,  

Protein Folding & ER Stress(tgid=8) ⓘ

CHOP/DDIT3↓, 1,   ER Stress↓, 1,   GRP78/BiP↓, 1,   HSP70/HSPA5↓, 1,   HSP70/HSPA5↑, 7,   HSP70/HSPA5↝, 1,   HSPs↑, 1,   IRE1↓, 1,  

Autophagy & Lysosomes(tgid=9) ⓘ

Beclin-1/ATG6↓, 1,   p62↑, 1,  

DNA Damage & Repair(tgid=10) ⓘ

p‑BRCA1↑, 1,   DNAdam↓, 2,   p16↓, 1,   P53↓, 2,   PCNA↓, 1,  

Cell Cycle & Senescence(tgid=11) ⓘ

CDK2↓, 1,   CDK4↓, 1,   cycD1/CCND1↓, 2,   cycE/CCNE↓, 1,   E2Fs↑, 2,   P21↓, 1,   RB1↓, 1,   TumCCA↑, 1,  

Proliferation, Differentiation & Cell State(tgid=12) ⓘ

BMP2↑, 1,   cFos↑, 1,   Diff↑, 1,   IGF-1↑, 2,   neuroG↑, 3,   TumCP↓, 1,  

Migration(tgid=13) ⓘ

AntiAg↑, 10,   AP-1↓, 4,   Ca+2↓, 1,   Ca+2↑, 1,   Ca+2↝, 1,   Cartilage↑, 1,   p‑Cofilin↑, 1,   COL1↑, 1,   EMT↑, 1,   LAMs↑, 1,   p‑MLC2/MYL9↑, 1,   MMP-10↓, 1,   MMP1↓, 2,   MMP2↓, 7,   MMP2↑, 2,   MMP3↓, 3,   MMP9↓, 32,   MMP9↑, 6,   MMPs↓, 2,   MYPT1 / PPP1R12A↑, 1,   p‑MYPT1 / PPP1R12A↑, 1,   ROCK1↑, 1,   Smad1↑, 1,   SMAD3↓, 1,   TGF-β↓, 4,   TGF-β↑, 2,   TGF-β1↓, 1,   TIMP1↓, 2,   TIMP1↑, 2,   TIMP2↑, 2,   TregCell↑, 1,   TumCI↓, 1,   TumMeta↓, 1,   α-SMA↓, 5,   β-catenin/ZEB1↑, 1,  

Angiogenesis & Vasculature(tgid=14) ⓘ

angioG↓, 1,   angioG↑, 3,   CD31/PECAM-1↓, 1,   eNOS↑, 2,   HIF-1↓, 1,   Hif1a↓, 1,   Hif1a↑, 1,   LOX1↓, 1,   NO↓, 15,   NO↑, 4,   VCAM-1↓, 5,   VEGF↓, 3,   VEGF↑, 6,   p‑VEGFR2/KDR/Flk1↓, 1,  

Barriers & Transport(tgid=15) ⓘ

BBB↓, 2,   BBB↑, 14,   BBB∅, 2,   CLDN1↝, 1,   GastroP↑, 2,   GLUT1↑, 1,   GLUT2↑, 1,   GLUT3↑, 1,   GLUT4↑, 3,   MMP↑, 10,   MMP∅, 1,   MUC19↓, 1,   MUC2↓, 1,   TJ↑, 1,   TRPM7↓, 1,   ZO-1↝, 1,  

Immune & Inflammatory Signaling(tgid=16) ⓘ

CD19↑, 1,   CD4+↑, 1,   COX1↓, 4,   COX2/PTGS2↓, 34,   CXCR4↓, 1,   Eos↓, 1,   HMGB1↓, 2,   ICAM-1↓, 3,   IFN-γ↓, 1,   IFN-γ↑, 1,   IL1↓, 3,   IL10↓, 1,   IL10↑, 5,   IL12↓, 3,   IL17↓, 3,   IL18↓, 2,   IL1β↓, 25,   IL2↑, 2,   IL23↓, 1,   IL4↓, 2,   IL4↑, 2,   IL5↓, 2,   IL6↓, 31,   IL8↓, 7,   Imm↑, 12,   Inflam↓, 85,   Inflam↑, 2,   IRF3↓, 1,   MCP1/CCL2↓, 3,   MyD88↓, 1,   NeuroI↓, 1,   NF-kB↓, 45,   NK cell↑, 1,   NLRP3↓, 6,   NLRP3↑, 1,   p65↓, 1,   PGE2↓, 14,   PGE2↑, 3,   RAGE↓, 1,   SOCS-3↓, 1,   Th1 response↓, 1,   Th2↑, 2,   TLR2↓, 3,   TLR4↓, 6,   TNF-α↓, 32,   TRIF↓, 1,  

Synaptic & Neurotransmission(tgid=18) ⓘ

5HT↑, 2,   Ach↑, 1,   AChE↓, 12,   AChE↑, 1,   BChE↓, 1,   BDNF↑, 9,   GABA↑, 3,   NGF↑, 2,   PSD95↑, 1,   SNAP25↑, 1,  

Protein Aggregation(tgid=19) ⓘ

AGEs↓, 3,   Aβ↓, 15,   BACE/β-secretase↓, 5,   tau↓, 1,   p‑tau↓, 1,   β-Amyloid↓, 1,  

Hormonal & Nuclear Receptors(tgid=20) ⓘ

AHR↓, 1,   CYP19↓, 1,   PPARγ↓, 1,   PPARγ↑, 4,  

Drug Metabolism & Resistance(tgid=21) ⓘ

BioAv↓, 28,   BioAv↑, 25,   BioAv↝, 19,   BioEnh↑, 1,   CompStab↑, 1,   CYP1A1↑, 1,   CYP1A2↑, 1,   CYP2E1↓, 1,   Dose⇅, 1,   Dose↝, 8,   eff↓, 2,   eff↑, 17,   eff↝, 1,   GSTA1↑, 1,   Half-Life↓, 3,   Half-Life↝, 6,   Half-Life∅, 1,   P-gp/ABCB1↓, 1,   P450↓, 3,   Synergy↑, 5,  

Clinical Biomarkers(tgid=22) ⓘ

ALAT↓, 8,   ALP↓, 3,   AST↓, 11,   BMD↑, 1,   BP↓, 2,   BP↝, 1,   p‑BRCA1↑, 1,   CRP↓, 5,   Hcy/homoC↓, 1,   IL6↓, 31,   LDH↓, 4,   LDH↑, 1,   NOS2↓, 2,   RAGE↓, 1,  

Functional Outcomes(tgid=23) ⓘ

Analgesic↑, 2,   AntiAge↑, 4,   antiAll↑, 14,   AntiArt↑, 7,   AntiCan↓, 1,   AntiCan↑, 16,   antiCG↑, 1,   AntiDiabetic↓, 1,   AntiDiabetic↑, 15,   antiPs↑, 1,   AntiTum↑, 5,   cardioP↑, 27,   CardioT↓, 1,   chemoP↑, 4,   chemoPv↑, 3,   cognitive↓, 1,   cognitive↑, 17,   diuretic↑, 3,   hepatoP↓, 1,   hepatoP↑, 24,   Learn↑, 2,   memory↑, 18,   motorD↑, 4,   Mucositis↓, 1,   neuroP↓, 2,   neuroP↑, 61,   Obesity↓, 4,   OS↑, 1,   Pain↓, 6,   QoL↑, 1,   radioP↑, 2,   RenoP↑, 5,   Risk↓, 1,   Stroke↓, 5,   toxicity↓, 20,   toxicity↑, 1,   toxicity↝, 6,   toxicity∅, 3,   Wound Healing↑, 2,  

Infection & Microbiome(tgid=24) ⓘ

AntiBio↑, 2,   AntiFungal↓, 1,   AntiFungal↑, 2,   AntiP↑, 1,   AntiViral↑, 7,   Bacteria↓, 19,   Diar↓, 1,   GutMicro↑, 4,   Sepsis↓, 1,  

Ingredients & Constituents(tgid=25) ⓘ

Ingr↝, 3,  
Total Targets: 379

Scientific Paper Hit Count for: MMP9, MMP9
19 Resveratrol
15 Fisetin
13 Curcumin
12 Thymoquinone
11 Matrine
11 Sulforaphane (mainly Broccoli)
9 Apigenin (mainly Parsley)
9 Baicalein
9 Berberine
9 Quercetin
9 Luteolin
9 Lycopene
8 Garcinol
8 Magnetic Fields
7 Boswellia (frankincense)
7 Propolis -bee glue
7 Capsaicin
7 Magnolol
7 Morin
6 Silver-NanoParticles
6 Alpha-Lipoic-Acid
6 Artemisinin
6 Caffeic acid
6 Chrysin
6 Diindolylmethane
6 Dandelion Root
6 EGCG (Epigallocatechin Gallate)
6 Eugenol
6 Honokiol
6 Kaempferol
6 Rosmarinic acid
5 Melatonin
5 Betulinic acid
5 Ellagic acid
5 Ferulic acid
5 Formononetin
5 Gambogic Acid
5 Nimbolide
5 Piperine
4 Cisplatin
4 Cucurbitacin
4 Pterostilbene
4 Silymarin (Milk Thistle) silibinin
4 Shikonin
4 Urolithin
3 Ascorbyl Palmitate
3 Celastrol
3 Hydroxycinnamic-acid
3 D-limonene
3 Emodin
3 phytic acid, Inositol hexakisphosphate
3 Magnetic Field Rotating
3 Phenethyl isothiocyanate
3 Piperlongumine
2 1,8-Cineole
2 Sorafenib (brand name Nexavar)
2 Astragalus
2 Paclitaxel/Taxol
2 alpha Linolenic acid
2 Radiotherapy/Radiation
2 Ashwagandha(Withaferin A)
2 Baicalin
2 Berbamine
2 Biochanin A
2 Caffeic Acid Phenethyl Ester (CAPE)
2 Carvacrol
2 Thymol-Thymus vulgaris
2 Celecoxib
2 Chlorogenic acid
2 chitosan
2 Cinnamon
2 Crocetin
2 CUSP9
2 Deguelin
2 Indole-3-carbinol
2 Evodiamine
2 tamoxifen
2 Fucoidan
2 Ginkgolic acids
2 Genistein (soy isoflavone)
2 Ginger/6-Shogaol/Gingerol
2 Graviola
2 Grapeseed extract
2 Proanthocyanidins
2 Hibiscus sabdariffa
2 HydroxyTyrosol
2 Inositol
2 Ivermectin
2 Juglone
2 Licorice
2 Mushroom Chaga, Inonotus obliquus
2 Mushroom Lion’s Mane, Hericium erinaceus
2 Naringin
2 Marjoram (Origanum majorana)
2 Selenite (Sodium)
2 Vitamin C (Ascorbic Acid)
1 2-DeoxyGlucose
1 3-bromopyruvate
1 Allicin (mainly Garlic)
1 Phyllanthus emblica/Emblica officinalis/Amla / Indian Gooseberry
1 Andrographis
1 Anethole/trans-Anethole
1 Isovitexin
1 Aspirin
1 Astaxanthin
1 Beta-Caryophyllene
1 Chemotherapy
1 Brucea javanica
1 brusatol
1 Bacopa monnieri
1 borneol
1 Carnosic acid
1 NTP, Non-Thermal Plasma,Cold Atmospheric Plasma
1 Cynanbungeigenin C (CBC) and D (CBD)
1 Centella asiatica / Gotu kola → asiaticoside
1 Selenium NanoParticles
1 Carvone
1 Cyclopamine
1 Cysteamine
1 Vitamin A, Retinoic Acid
1 Folic Acid, Vit B9
1 Bortezomib
1 Flaxseed/Linseed
1 Gallic acid
1 Ginkgo biloba
1 Geraniol
1 Ginkgetin
1 Hops (Humulus lupulus)
1 Hyperoside
1 Isobavachalcone
1 Isoliquiritigenin
1 isoorientin
1 Plumbagin
1 Lactobacillus
1 Licochalcone A
1 Methylglyoxal
1 Methylsulfonylmethane
1 Myricetin
1 Niclosamide (Niclocide)
1 Propyl gallate
1 temozolomide
1 Polyphenols
1 Parthenolide
1 Sanguinarine
1 Sesame seeds and Oil
1 Salvia miltiorrhiza
1 Aflavin-3,3′-digallate
1 Turmerones
1 VitK3,menadione
Query results interpretion may depend on "conditions" listed in the research papers.
Such Conditions may include : 
  -low or high Dose
  -format for product, such as nano of lipid formations
  -different cell line effects
  -synergies with other products 
  -if effect was for normal or cancerous cells

Filter Conditions: Pro/AntiFlg:%  IllCat:%  CanType:%  Cells:%  prod#:%  Target#:203  State#:%  Dir#:%
  wNotes=0  sortOrder:rid,rpid

 

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