| Source: HalifaxProj (block) |
| Type: |
| Tumor Necrosis Factor-alpha (TNF-α) is a cytokine that plays a complex role in cancer biology. It is primarily produced by activated macrophages and is involved in systemic inflammation.
TNF-α is a pro-inflammatory cytokine that can promote inflammation, which is a known factor in cancer development. Overall, the expression of TNF-α in cancers is often linked to inflammation, tumor progression, and the tumor microenvironment. |
| 6365- | DRE, | AN OVERVIEW OF THERAPEUTIC POTENTIALS OF TARAXACUM OFFICINALE (DANDELION): A TRADITIONALLY VALUABLE HERB WITH A REACH HISTORICAL BACKGROUND |
| - | Review, | Var, | NA |
| 6358- | DRE, | Dandelion root extracts and taraxasterol inhibit LPS‑induced colorectal cancer cell viability by blocking TLR4‑NFκB‑driven ACE2 and TMPRSS2 pathways |
| - | in-vitro, | CRC, | NA |
| 6363- | DRE, | Therapeutic Potential of Dandelion (Taraxacum officinale) Root Extract in Colon Cancer: A Comprehensive Review |
| - | in-vitro, | CRC, | NA |
| 1620- | EA, | Rad, | Radiosensitizing effect of ellagic acid on growth of Hepatocellular carcinoma cells: an in vitro study |
| - | in-vitro, | Liver, | HepG2 |
| 6613- | Ech, | Bioavailability and pharmacokinetics of Echinacea purpurea preparations and their interaction with the immune system |
| - | Study, | Nor, | NA |
| 3227- | EGCG, | Epigallocatechin-3-gallate treatment to promote neuroprotection and functional recovery after nervous system injury |
| - | NA, | Nor, | NA |
| 3225- | EGCG, | Epigallocatechin‐3‐Gallate Ameliorates Diabetic Kidney Disease by Inhibiting the TXNIP/NLRP3/IL‐1β Signaling Pathway |
| - | in-vitro, | Nor, | NA | - | in-vivo, | Nor, | NA |
| 3238- | EGCG, | Green tea catechin, epigallocatechin-3-gallate (EGCG): mechanisms, perspectives and clinical applications |
| - | Review, | Var, | NA |
| 3201- | EGCG, | Epigallocatechin Gallate (EGCG): Pharmacological Properties, Biological Activities and Therapeutic Potential |
| - | Review, | NA, | NA |
| 3594- | EGCG, | Epigallocatechin-3-gallate inhibits secretion of TNF-alpha, IL-6 and IL-8 through the attenuation of ERK and NF-kappaB in HMC-1 cells |
| - | in-vitro, | AD, | HMC1 |
| 6780- | EGCG, | The pharmacological activity of epigallocatechin-3-gallate (EGCG) on Alzheimer's disease animal model: A systematic review |
| - | Review, | AD, | NA |
| 6784- | EGCG, | Dietary (−)-Epigallocatechin Gallate (EGCG): State-of-the-Art Advances in Bioactivities, Bioavailability Enhancement Strategies, and Applications in Nutrition and Health |
| - | Review, | Nor, | NA |
| 26- | EGCG, | QC, | docx, | Green tea and quercetin sensitize PC-3 xenograft prostate tumors to docetaxel chemotherapy |
| - | vitro+vivo, | Pca, | PC3 |
| 20- | EGCG, | Potential Therapeutic Targets of Epigallocatechin Gallate (EGCG), the Most Abundant Catechin in Green Tea, and Its Role in the Therapy of Various Types of Cancer |
| - | in-vivo, | Liver, | NA | - | in-vivo, | Tong, | NA |
| 2992- | EGCG, | Effects of Epigallocatechin-3-Gallate on Matrix Metalloproteinases in Terms of Its Anticancer Activity |
| - | Review, | Var, | NA |
| 6814- | EMD, | Emodin: A Review of its Pharmacology, Toxicity and Pharmacokinetics |
| - | Review, | Nor, | NA |
| 6818- | EMD, | Emodin Rescued Hyperhomocysteinemia-Induced Dementia and Alzheimer's Disease-Like Features in Rats |
| - | in-vivo, | AD, | NA |
| 6819- | EMD, | Recent advances in the therapeutic potential of emodin for human health |
| - | Review, | Nor, | NA |
| 6820- | EMD, | The Health Benefits of Emodin, a Natural Anthraquinone Derived from Rhubarb—A Summary Update |
| - | Review, | Nor, | NA | - | Review, | Arthritis, | NA | - | Review, | AD, | NA |
| 6827- | EMD, | Mechanism of Emodin in the Treatment of Rheumatoid Arthritis |
| - | Review, | Arthritis, | NA |
| 6829- | EMD, | Molecular Mechanisms of Action of Emodin: As an Anti-Cardiovascular Disease Drug |
| 6792- | EPA, | Effect of Eicosapentaenoic Acid on Body Composition and Inflammation Markers in Patients with Head and Neck Squamous Cell Cancer from a Public Hospital in Mexico |
| - | Trial, | HNSCC, | NA |
| 6381- | Eug, | Biological Properties and Prospects for the Application of Eugenol—A Review |
| - | Review, | Var, | NA |
| 6385- | Eug, | Anticancer potential of eugenol in hepatocellular carcinoma through modulation of oxidative stress, inflammation, apoptosis, and proliferation mechanisms |
| - | in-vivo, | HCC, | HepG2 |
| 6388- | Eug, | Eugenol’s anti-cancer properties, its modulation of signalling pathways, and cascades across various cancers: A review |
| - | Review, | Var, | NA |
| 6325- | Eug, | Anticancer Properties of Eugenol: A Review |
| - | Review, | Var, | NA |
| 6323- | Eug, | Eugenol: An Insight Into the Anticancer Perspective and Pharmacological Aspects |
| - | Review, | Var, | NA | - | Review, | Arthritis, | NA |
| 5055- | Ex, | Why exercise has a crucial role in cancer prevention, risk reduction and improved outcomes |
| - | Review, | Var, | NA |
| 4070- | FA, | Folic Acid Supplementation Mitigates Alzheimer's Disease by Reducing Inflammation: A Randomized Controlled Trial |
| - | Trial, | AD, | NA |
| 3714- | FA, | Recent Advances in the Neuroprotective Properties of Ferulic Acid in Alzheimer's Disease: A Narrative Review |
| - | Review, | AD, | NA |
| 3778- | FA, | Recent Advances in the Neuroprotective Properties of Ferulic Acid in Alzheimer’s Disease: A Narrative Review |
| - | Review, | AD, | NA |
| 6871- | FA, | Sesame, | Nano-encapsulated ferulic acid in sesame protein isolate alleviates acrylamide-induced liver toxicity and genotoxicity in rats via oxidative stress and DNA damage modulation |
| - | in-vivo, | Nor, | NA |
| 6886- | FA, | MTX, | Ferulic acid prevents oxidative stress, inflammation, and liver injury via upregulation of Nrf2/HO-1 signaling in methotrexate-induced rats |
| - | in-vivo, | Nor, | NA |
| 6885- | FA, | Mitigation of renal toxicity induced by paraquat using ferulic acid: Role of inflammatory pathways |
| - | in-vivo, | Nor, | NA |
| - | Trial, | AD, | NA |
| 6951- | FA, | Folic acid supplementation improves cognitive function by reducing the levels of peripheral inflammatory cytokines in elderly Chinese subjects with MCI |
| - | Trial, | AD, | NA |
| 6954- | FA, | Folic acid as a potential therapeutic agent for Alzheimer's disease: Effects on inflammatory cytokines, amyloid deposition, and neurotransmitter metabolism |
| - | Trial, | AD, | NA |
| 2861- | FIS, | The neuroprotective effects of fisetin, a natural flavonoid in neurodegenerative diseases: Focus on the role of oxidative stress |
| - | Review, | Nor, | NA | - | Review, | Stroke, | NA | - | Review, | Park, | NA |
| 2827- | FIS, | The Potential Role of Fisetin, a Flavonoid in Cancer Prevention and Treatment |
| - | Review, | Var, | NA |
| 2841- | FIS, | Fisetin, an Anti-Inflammatory Agent, Overcomes Radioresistance by Activating the PERK-ATF4-CHOP Axis in Liver Cancer |
| - | in-vitro, | Nor, | RAW264.7 | - | in-vitro, | Liver, | HepG2 | - | in-vitro, | Liver, | Hep3B | - | in-vitro, | Liver, | HUH7 |
| 2843- | FIS, | Fisetin and Quercetin: Promising Flavonoids with Chemopreventive Potential |
| - | Review, | Var, | NA |
| 5392- | FIS, | AsP, | Fisetin topical delivery via ascorbyl palmitate/hyaluronan-enhanced limosomes: a novel paradigm for preventing UVB-induced skin photoaging |
| - | in-vivo, | Nor, | NA |
| 6919- | FIS, | Inhibition of c-Jun N-terminal kinase and nuclear factor κ B pathways mediates fisetin-exerted anti-inflammatory activity in lipopolysccharide-treated RAW264.7 cells |
| 6981- | Form, | Formononetin: a review of its source, pharmacology, drug combination, toxicity, derivatives, and drug delivery systems |
| - | Review, | Var, | NA | - | Review, | AD, | NA | - | Review, | PSA, | NA |
| 6995- | Form, | Formononetin inhibits neuroinflammation and increases estrogen receptor beta (ERβ) protein expression in BV2 microglia |
| - | Review, | Nor, | BV2 |
| 7021- | Fuc, | Fucoidan Prevents the Progression of Osteoarthritis in Rats |
| - | in-vivo, | Arthritis, | NA |
| 7003- | Fuc, | Chemo, | An Exploratory Study on the Anti-inflammatory Effects of Fucoidan in Relation to Quality of Life in Advanced Cancer Patients |
| 4030- | FulvicA, | Therapeutic Potential of Fulvic Acid in Chronic Inflammatory Diseases and Diabetes |
| - | Review, | NA, | NA |
| 7035- | GA, | Gallic acid attenuates LPS-induced inflammation in Caco-2 cells by suppressing the activation of the NF-κB/MAPK signaling pathway |
| - | in-vitro, | IBD, | Caco-2 |
Query results interpretion may depend on "conditions" listed in the research papers. Such Conditions may include : -low or high Dose -format for product, such as nano of lipid formations -different cell line effects -synergies with other products -if effect was for normal or cancerous cells
Filter Conditions: Pro/AntiFlg:% IllCat:% CanType:% Cells:% prod#:% Target#:309 State#:% Dir#:%
wNotes=0 sortOrder:rid,rpid