other Cancer Research Results

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7419- CS,    Artichoke leaf extract (Cynara scolymus) reduces plasma cholesterol in otherwise healthy hypercholesterolemic adults: a randomized, double blind placebo controlled trial
- Trial, Nor, NA
*Dose↝, *other↓,
7413- CS,  Poly,    Anticancer effects induced by artichoke extract in oral squamous carcinoma cell lines
- in-vitro, SCC, SCC25
AntiCan↑, tumCV↓, TumCG↓, Apoptosis↑, selectivity↑, BAX↑, Casp9↑, Bcl-2↓, TumCCA↑, other↝, hepatoP↑,
7410- CS,    Artichoke polyphenols induce apoptosis and decrease the invasive potential of the human breast cancer cell line MDA-MB231
- in-vitro, BC, MDA-MB-231
selectivity↑, other↝, Apoptosis↑, DR4↑, Casp9↑, Casp8↑, Bax:Bcl2↑, P21↑, MMP↓, TumCI↓, MMP2↓,
1570- Cu,    Development of copper nanoparticles and their prospective uses as antioxidants, antimicrobials, anticancer agents in the pharmaceutical sector
- Review, NA, NA
selectivity↑, antiOx↑, ROS↑, ChemoSen↑, GSH↓, lipid-P↑, Catalase↓, SOD↓, other↑,
1596- Cu,  CDT,    Unveiling the promising anticancer effect of copper-based compounds: a comprehensive review
- Review, NA, NA
TumCD↑, Apoptosis↓, ROS↑, angioG↑, Cupro↑, Paraptosis↑, eff↑, eff↓, selectivity↑, DNAdam↑, eff↑, eff↑, eff↑, eff↑, Fenton↑, H2O2↑, eff↑, eff↑, eff↑, RadioS↑, ChemoSen↑, eff↑, *toxicity↝, other↑, eff↑,
6171- Cu,    Copper in the tumor microenvironment and tumor metastasis
- Review, Var, NA
*angioG↑, other↑, *ROS↑, CTR1↝, other↝, COX17↝, ATOX1↝,
6211- CUR,    The effect of curcumin on hypoxia in the tumour microenvironment as a regulatory factor in cancer
- Review, Var, NA
HIF-1↓, VEGF↓, angioG↓, RadioS↑, ChemoSen↑, other↝, Apoptosis↑, TumCG↓, TumMeta↓, BioAv↓, COX2/PTGS2↓, CD31/PECAM-1↓, IL8↓, TGF-β↓, NF-kB↓, JAK2↓, STAT3↓, CompStab↓,
6228- CUR,    A pharmacokinetic study and critical reappraisal of curcumin formulations enhancing bioavailability
- Study, Nor, NA
*BioAv↓, *other↓,
6209- CUR,    Curcumin as a complementary treatment in oncological therapy: a systematic review
- Review, Var, NA
other↝, eff↓, *BioAv↓, ChemoSen↓,
132- CUR,    Targeting multiple pro-apoptotic signaling pathways with curcumin in prostate cancer cells
- in-vitro, Pca, PC3
TumCCA↑, ROS↑, TumAuto↑, UPR↑, ER Stress↑, Casp3↑, Casp9↑, Casp12↑, PARP↑, other↝, GRP78/BiP↑, PDI↑, eIF2α↑, other↝,
3760- CUR,  GI,  CAP,  RosA,  PI  Extending the lore of curcumin as dipteran Butyrylcholine esterase (BChE) inhibitor: A holistic molecular interplay assessment
- Review, Nor, NA
*AChE↓, *other↓, *other↓, *other↓, *other↓, *other↓, *other↓, *BChE↓,
2818- CUR,    Novel Insight to Neuroprotective Potential of Curcumin: A Mechanistic Review of Possible Involvement of Mitochondrial Biogenesis and PI3/Akt/ GSK3 or PI3/Akt/CREB/BDNF Signaling Pathways
- Review, AD, NA
*neuroP↑, *ROS↓, *Inflam↓, *Apoptosis↓, *cognitive↑, *cardioP↑, other↑, *COX2/PTGS2↓, *IL1β↓, *TNF-α↓, NF-kB↓, *PGE2↓, *iNOS↓, *NO↓, *IL2↓, *IL4↓, *IL6↓, *INF-γ↓, *GSK‐3β↓, *STAT↓, *GSH↑, *MDA↓, *lipid-P↓, *SOD↑, *GPx↑, *Catalase↑, *GSR↓, *LDH↓, *H2O2↓, *Casp3↓, *Casp9↓, *NRF2↑, *AIF↓, *ATP↑,
6237- CUSP9,    CUSP9* treatment protocol for recurrent glioblastoma: aprepitant, artesunate, auranofin, captopril, celecoxib, disulfiram, itraconazole, ritonavir, sertraline augmenting continuous low dose temozolomide
- in-vitro, GBM, NA
PI3K↓, Akt↓, ROS↑, NF-kB↓, TNF-α↓, TLR2↓, other↓, TrxR↓, STAT3↓, MMPs↓, COX1↓, COX2/PTGS2↓, CA↓, ALDH↓, P-gp/ABCB1↓, HH↓, 5LO↓, mTOR↓, CycD3↓, Proteasome↓, other↓, MMP2↓, MMP9↓, ALDH↓, Copper↓,
6233- CUSP9,    A conceptually new treatment approach for relapsed glioblastoma: Coordinated undermining of survival paths with nine repurposed drugs CUSP9 by the International Initiative for Accelerated Improvement of Glioblastoma Care
- Review, GBM, NA
other↝, QoL↑,
6250- Cyc,    Dose- and route-dependent teratogenicity, toxicity, and pharmacokinetic profiles of the hedgehog signaling antagonist cyclopamine in the mouse
- in-vivo, Nor, NA
*HH↓, *other↑,
7451- CYN,    Inhibitory effects of cynaropicrin on human melanoma progression by targeting MAPK, NF‐κB, and Nrf‐2 signaling pathways in vitro
- in-vitro, Melanoma, A375
TumCP↓, Casp3↑, Apoptosis↑, TumCMig↓, TumCI↓, ERK↓, NF-kB↓, ROS↓, HO-1↑, NRF2↑, Bcl-2↓, NF-kB↓, other↝,
4332- Cyste,    Cystamine metabolism and brain transport properties: clinical implications for neurodegenerative diseases
- in-vivo, Park, NA - in-vivo, HD, NA
*neuroP↑, *other↝, *other↝,
6592- DAS,    Final 5-Year Study Results of DASISION: The Dasatinib Versus Imatinib Study in Treatment-Naïve Chronic Myeloid Leukemia Patients Trial
- Trial, CML, NA
Dose↝, other↝, OS↑,
6683- DCA,    Dichloroacetate for Cancer Treatment: Some Facts and Many Doubts
- Review, Var, NA
PDK1 / PDPK1↓, lactateProd↓, Apoptosis↑, TumCP↓, selectivity↑, other↝, Dose↝, BioAv↑, Half-Life↓, Glycolysis↓, OXPHOS↑, Casp↑, i-pH↓, COX2/PTGS2↑, Hif1a↓, angioG↓, HMG-CoA↓, GSTZ1↓, OCR↑, lipoGen↓, fatigue↓, survivin↓, miR-375↑, eff↓, CSCs↓, TumAuto↑, mTOR↓, TumCI↓, TumVol↓, TumW↓, ATP↓, Warburg↓, eff↑, e-pH↑, Synergy↑, Synergy↑, other↝, RadioS↑, toxicity↓, Dose↝, Synergy↑, Synergy↑, Synergy↑, toxicity↝, eff↓,
1872- DCA,    Dichloroacetate, a selective mitochondria-targeting drug for oral squamous cell carcinoma: a metabolic perspective of treatment
- in-vitro, Oral, HSC2 - in-vitro, Oral, HSC3
PDKs↓, ROS↑, OCR↑, other↑,
6669- Deg,    Mitochondrial Complex I Inhibitors Expose a Vulnerability for Selective Killing of Pten-Null Cells
- vitro+vivo, Pca, NA
other↝, ETC↓, TumCG↓, OCR↓, GlucoseCon↑, MMP↓, other↝,
6704- DFC,    Diclofenac demonstrates notable anticancer properties
- Review, Var, NA
TumMeta↓, other↝,
6688- DFC,    New Aspects of an Old Drug – Diclofenac Targets MYC and Glucose Metabolism in Tumor Cells
- in-vivo, lymphoma, U937
AntiCan↑, COX2/PTGS2↓, Myc↓, GLUT1↓, LDHA↓, MCT1↓, GlucoseCon↓, lactateProd↓, TumCP↓, other∅, toxicity↝,
6695- DFC,    Inhibition of lactate dehydrogenase A by diclofenac sodium induces apoptosis in HeLa cells through activation of AMPK
- in-vitro, Cerv, HeLa
other↝, Glycolysis↓, LDHA↓, Hypoxia↓, Apoptosis↑, lactateProd↓, ATP↓, mt-ROS↑, DNAdam↑, lipid-P↑, AMPK↑, p‑S6K↓, TumCP↓, Dose↝, selectivity↑, i-MDA↑, mtDam↑,
6666- DFE,    The impact of date palm fruits and their component polyphenols, on gut microbial ecology, bacterial metabolites and colon cancer cell proliferation
- in-vitro, Colon, Caco-2
*Fibre↑, *Poly↑, *other↝, *QC↑, *Api↑, *Myr↑, *LT↑, TumCP↓, *GutMicro↑, *Inflam↓, *antiOx↑,
6663- DFE,    Nutraceuticals of Phoenix dactylifera L.: Physicochemistry, Nutritional Value and Therapeutic Potential
- Review, Nor, NA - Review, AD, NA
*antiOx↑, *Inflam↓, *AntiBio↑, *AntiDiabetic↑, *AntiCan↑, *AntiArt↑, *neuroP↑, *hepatoP↑, *GastroP↑, *other↝, *cardioP↑, *cognitive↑, *ROS↓, *memory↑, *other↝, *SOD↑, *Catalase↑, *GSH↑, *GA↑, *Catechins↑, *FA↑, *QC↑, Api↑, *CA↑, *Imm↑, *Phen↑, *IL1β↓, *TGF-β↓, *COX1↓, *COX2/PTGS2↓, TumCP↓, Casp3↑, TumMeta↓, *GutMicro↑,
6755- DHA,    Baseline Findings of PreventE4: A Double-Blind Placebo Controlled Clinical Trial Testing High Dose DHA in APOE4 Carriers before the Onset of Dementia
- Trial, AD, NA
*other↝,
6721- DHCA,    Dihydrocaffeic Acid—Is It the Less Known but Equally Valuable Phenolic Acid?
- Review, Nor, NA
*ROS↓, *Inflam↓, *eff↑, *other↝, *IL1β↓, *IL8↓, *TNF-α↓,
6710- dietF,    The International Scientific Association for Probiotics and Prebiotics (ISAPP) consensus statement on fermented foods
- Review, Nor, NA
*other↝, *toxicity↓, *toxicity↓, *Obesity↓, *AntiDiabetic↑, *cardioP↑, *GutMicro↑, *Imm↑,
2170- dietMet,    Low Protein Intake is Associated with a Major Reduction in IGF-1, Cancer, and Overall Mortality in the 65 and Younger but Not Older Population
- Study, Var, NA
OS↑, eff↝, other↝,
5193- dietMet,  Rad,    A Phase I Trial of a Methionine Restricted Diet with Concurrent Radiation Therapy
- Trial, Var, NA
toxicity↝, other↝,
5190- dietMet,    Methionine restriction activates the integrated stress response in triple-negative breast cancer cells by a GCN2- and PERK-independent mechanism
- in-vitro, BC, MDA-MB-231 - in-vitro, BC, MDA-MB-468
p‑eIF2α↑, ATF4↑, SESN2↑, TumCCA↑, Apoptosis↑, other↑,
5065- dietSTF,  dietFMD,    Nutrition, GH/IGF-I Signaling, and Cancer
- Review, Var, NA
GH↓, IGF-1↓, glucose↓, IGFBP1↑, OS↑, Imm↑, neuroP↑, BMD↑, Dose↝, Risk↓, other↑, TumCP↓,
6736- Dipy,    Nucleoside Transport Inhibition by Dipyridamole Prevents Angiogenesis Impairment by Homocysteine and Adenosine
- in-vitro, Nor, NA
*other↝, *p‑MEK↑, *ERK↑, *angioG↑,
6267- DL,    Effect of d-limonene and its derivatives on breast cancer in human trials: a scoping review and narrative synthesis
- Review, BC, NA
*toxicity↓, cycD1/CCND1↓, TumCP↓, other↑,
6268- DL,    Modulation of the mevalonate pathway and cell growth by pravastatin and d-limonene in a human hepatoma cell line (Hep G2)
- in-vitro, Liver, HepG2
other↑,
6272- DL,    Anti‐leukemic and anti‐angiogenic effects of d‐Limonene on K562‐implanted C57BL/6 mice and the chick chorioallantoic membrane model
- vitro+vivo, CLL, NA
angioG↓, other↓,
6288- DL,    From Citrus to Clinic: Limonene’s Journey Through Preclinical Research, Clinical Trials, and Formulation Innovations
- Review, Var, NA - Review, AD, NA
other↑, DDS↑, *antiOx↑, *Inflam↓, *AntiDiabetic↑, *neuroP↑, *Imm↑, *Wound Healing↑, *other↑, *BioAv↑, *ROS↓, *SOD↑, *Catalase↑, *GSH↑, *DNAdam↓, *AntiDiabetic↑, Casp3↑, Casp9↑, BAX↑, Bcl-2↓, *AChE↓, *BChE↓, *Aβ↓, *ROS↓, *toxicity?,
6284- DL,    Chemoprevention and therapy of cancer by d-limonene
- in-vivo, Var, NA
chemoPv↑, other↑,
6727- DMSO,    The permeability enhancing mechanism of DMSO in ceramide bilayers simulated by molecular dynamics
- in-vitro, Var, NA
other↑,
6723- DMSO,    Modulating the structure and properties of cell membranes: the molecular mechanism of action of dimethyl sulfoxide
- Review, Nor, NA
*BioEnh↑, *other↝,
6344- DRE,    Dandelion: Purported Benefits, Side Effects & More
- Review, Var, NA
*other↝, *hepatoP↑, *ALAT↓, *MDA↓, *TNF-α↓, *IL6↓, *antiOx↑, *Inflam↓, *proCasp3↓, Casp3↑, tumCV↓, TNF-α↑, IL1↑,
6346- DRE,    Unusual Response of Acute Monocytic Leukemia to Dandelion Root Extract
- Case Report, AML, NA
QoL↑, other↑, Dose↝,
6349- DRE,    Dandelion root extract protects NCM460 colonic cells and relieves experimental mouse colitis
- vitro+vivo, Nor, NCM460
*Apoptosis↓, *ROS↓, *NF-kB↓, *other↓,
6352- DRE,    Investigation of the Anti-Lung Cancer Mechanisms of Taraxacum officinale Based on Network Pharmacology and Multidimensional Experimental Validation
- in-vitro, Lung, A549 - in-vitro, Nor, L929
other↝, other↝, tumCV↑, selectivity?, EGFR↓, AKT1↓, NQO1↓,
6740- DSF,    Targeting the NPL4 Adaptor of p97/VCP Segregase by Disulfiram as an Emerging Cancer Vulnerability Evokes Replication Stress and DNA Damage while Silencing the ATR Pathway
- in-vitro, Var, NA
NPL4↓, other↝, DNAdam↑,
6805- EA,    The gut microbiota urolithin metabotypes revisited: the human metabolism of ellagic acid is mainly determined by aging
- Human, Nor, NA
*other↝, other↝,
6804- EA,    Ellagic acid metabolism by human gut microbiota: consistent observation of three urolithin phenotypes in intervention trials, independent of food source, age, and health status
- Human, Nor, NA
*other?, *Risk↓, *GutMicro↝,
6603- Ech,  doxoR,    The effect of Echinacea purpurea on the pharmacokinetics of docetaxel
- Trial, Var, NA
other∅, other↝, Imm↑, CYP3A4⇅, other↑,
6620- Ech,    Echinacea purpurea diminishes neovascular reaction induced in mice skin by human cancer cells and stimulates non-specific cellular immunity in humans
- in-vivo, Var, NA
angioG↓, *NK cell↑, Imm↑, Inflam↓, tumCV↓, Apoptosis↑, Casp3↑, Casp7↑, DNAdam↑, MMPs↓, other↑,

Showing Research Papers: 201 to 250 of 666
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* indicates research on normal cells as opposed to diseased cells
Total Research Paper Matches: 666

Pathway results for Effect on Cancer / Diseased Cells:


NA, unassigned(tgid=0) ⓘ

NA↑, 1,   NA↝, 1,  

Redox & Oxidative Stress(tgid=1) ⓘ

antiOx↑, 4,   antiOx⇅, 2,   ARE↓, 1,   Catalase↓, 4,   Catalase↑, 3,   Copper↓, 1,   CoQ10↝, 1,   Fenton↑, 4,   GPx↓, 1,   GPx↑, 1,   GPx4↓, 5,   GSH↓, 13,   GSH↝, 1,   GSH∅, 1,   GSR↓, 1,   GSSG↑, 1,   GSTs↓, 1,   H2O2↑, 6,   HO-1↓, 2,   HO-1↑, 4,   Iron↑, 2,   Iron↝, 1,   Keap1↓, 1,   lipid-P↓, 2,   lipid-P↑, 11,   lipid-P↝, 1,   lipidDe↓, 1,   MDA↓, 1,   i-MDA↑, 1,   MGO↑, 1,   NADH↓, 2,   NQO1↓, 1,   NQO1↑, 1,   NRF2↓, 3,   NRF2↑, 7,   NRF2↝, 1,   Prx↓, 1,   Prx↑, 1,   RNS↑, 1,   ROS?, 2,   ROS↓, 6,   ROS↑, 93,   ROS⇅, 3,   ROS↝, 2,   i-ROS↑, 2,   mt-ROS↓, 1,   mt-ROS↑, 5,   SOD↓, 4,   SOD↑, 2,   Thiols↓, 2,   Trx↓, 1,   Trx↑, 1,   TrxR↓, 3,   TrxR↑, 1,   TrxR1↓, 2,   xCT/SLC7A11↓, 2,  

Metal & Cofactor Biology(tgid=2) ⓘ

ATOX1↝, 1,   Ferritin↑, 1,   IronCh↑, 2,   Mets↑, 1,  

Mitochondria & Bioenergetics(tgid=3) ⓘ

CDC25↓, 3,   CDC25↝, 1,   compI↑, 1,   compII↑, 1,   compIII↑, 1,   ETC↓, 5,   Insulin↓, 1,   mitResp↓, 1,   mRET↑, 1,   mtDam↑, 6,   OCR↓, 3,   OCR↑, 4,   OXPHOS↓, 2,   OXPHOS↑, 3,   OXPHOS↝, 1,   PDH↑, 3,   PGC-1α↑, 1,   SIRT3↑, 1,  

Core Metabolism/Glycolysis(tgid=4) ⓘ

5LO↓, 1,   ACC↓, 1,   ACLY↓, 6,   ACSL4↑, 1,   ALAT↓, 3,   AMPK↑, 9,   ATP↓, 10,   ATP↑, 1,   ATP∅, 1,   ECAR↓, 3,   FAM↝, 1,   FAO↑, 1,   FASN↓, 1,   FDG↓, 1,   glucose↓, 2,   glucose↝, 1,   GlucoseCon↓, 3,   GlucoseCon↑, 1,   GlucoseCon↝, 1,   GlutMet↓, 1,   Glycolysis↓, 16,   GSK‐3β↓, 2,   HK2↓, 5,   HMG-CoA↓, 2,   lactateProd↓, 8,   LDHA↓, 4,   lipoGen↓, 2,   NAD↓, 1,   NADPH↓, 2,   NADPH↑, 2,   OAA↑, 1,   PDK1 / PDPK1↓, 1,   PDKs↓, 2,   PFK1↓, 1,   PFK2↓, 1,   PGE3↑, 1,   PKM2↓, 5,   PPP↓, 2,   PPP↑, 1,   SCD1↓, 2,   SCP2↓, 1,   SIRT1↓, 1,   SIRT1↑, 1,   SREBP1/SREBF1↓, 1,   SREBP2↓, 1,   Warburg↓, 5,  

Cell Death(tgid=5) ⓘ

AIF↑, 2,   APAF1↑, 2,   Apoptosis↓, 1,   Apoptosis↑, 70,   ASK1↑, 1,   Bak↑, 2,   BAX↑, 19,   Bax:Bcl2↑, 4,   Bcl-2↓, 24,   Bcl-xL↓, 6,   BID↑, 1,   BNIP3↝, 1,   Casp↑, 9,   Casp10↑, 1,   Casp12↑, 2,   Casp2↑, 1,   Casp3↓, 2,   Casp3↑, 27,   cl‑Casp3↑, 6,   Casp7↑, 2,   Casp8↑, 7,   cl‑Casp8↑, 1,   Casp9↑, 18,   cl‑Casp9↑, 4,   cFLIP↓, 1,   Cupro↑, 1,   Cyt‑c↓, 1,   Cyt‑c↑, 15,   Cyt‑c↝, 4,   DR5↑, 3,   Fas↑, 6,   FasL↑, 4,   Ferroptosis↓, 1,   Ferroptosis↑, 7,   IAP1↓, 2,   IAP2/BIRC3↓, 1,   iNOS↓, 3,   iNOS↑, 1,   Mcl-1↓, 4,   MDM2↓, 3,   MOMP↑, 2,   Necroptosis↑, 2,   necrosis↑, 2,   NOXA↑, 1,   p38↑, 5,   p‑p38↑, 2,   Paraptosis↑, 1,   pS2/TFF1↓, 1,   Pyro↑, 1,   RIP1↓, 1,   survivin↓, 9,   TNFR 1↑, 1,   TRAILR↑, 1,   TumCD↓, 1,   TumCD↑, 13,   TumCD∅, 1,   XIAP↓, 8,  

Kinase & Signal Transduction(tgid=6) ⓘ

Akt↓, 24,   Akt↑, 2,   p‑Akt↓, 5,   AKT1↓, 2,   Akt2↓, 1,   EGFR↓, 11,   ERK↓, 12,   ERK↑, 3,   p‑ERK↓, 2,   p‑ERK↑, 1,   p‑ERK↝, 1,   FGFR2↓, 1,   FLT3↓, 1,   HCAR2↑, 2,   HER2/EBBR2↓, 4,   HGF/c-Met↓, 1,   IGF-1R↓, 2,   IKKα↓, 2,   JAK↓, 1,   JAK2↓, 1,   JAK3↓, 1,   JNK↓, 3,   JNK↑, 8,   MAPK↓, 7,   MAPK↑, 4,   MEK↓, 1,   mTOR↓, 9,   mTOR↑, 1,   P70S6K↓, 1,   PI3K↓, 19,   p‑PI3K↓, 1,   PKCδ↓, 4,   PTEN↑, 2,   c-Raf↓, 1,   RAS↓, 3,   RET↓, 1,   p‑S6K↓, 1,   Sp1/3/4↓, 4,   Src↓, 1,   STAT↓, 1,   STAT3↓, 7,   STAT3↑, 1,   p‑STAT3↓, 2,  

Transcription & Epigenetics(tgid=7) ⓘ

ATF4↑, 1,   cJun↑, 1,   cMyc↓, 5,   cMyc↑, 1,   DNMT1↓, 1,   DNMTs↓, 2,   EZH2↓, 1,   FOXO↑, 1,   FOXO1↑, 1,   FOXO3↑, 1,   ac‑H3↓, 1,   ac‑H4↓, 2,   HATs↓, 1,   HATs↑, 1,   HDAC↓, 7,   miR-124-3p↓, 1,   miR-375↑, 1,   Myc↓, 1,   other?, 13,   other↓, 64,   other↑, 105,   other⇅, 2,   other↝, 218,   other∅, 14,   sonoS↑, 1,   SOX2↓, 1,   SOX4↓, 1,   tumCV↓, 11,   tumCV↑, 1,   UrinaryC↑, 1,   Wmax↑, 1,   YMcells↑, 1,  

Protein Folding & ER Stress(tgid=8) ⓘ

CHOP/DDIT3↑, 3,   COX17↝, 1,   CUL1↝, 1,   CUL5↝, 1,   eIF2α↑, 2,   p‑eIF2α↑, 1,   ER Stress↓, 2,   ER Stress↑, 9,   GRP78/BiP↓, 1,   GRP78/BiP↑, 1,   HSP27↓, 2,   HSP27↑, 1,   HSP70/HSPA5↓, 2,   HSP70/HSPA5↑, 1,   HSP90↓, 8,   HSPs↑, 1,   IRE1↓, 1,   NPL4↓, 1,   PDI↑, 2,   PERK↑, 1,   Proteasome↓, 1,   UPR↑, 3,   mt-UPR↑, 1,  

Autophagy & Lysosomes(tgid=9) ⓘ

ATG5↑, 1,   autoF↓, 1,   Beclin-1/ATG6↑, 2,   CTSB↓, 1,   CTSL↓, 1,   CTSS↓, 1,   CTSZ↓, 1,   LC3‑Ⅱ/LC3‑Ⅰ↑, 3,   LC3B↑, 1,   LC3I↑, 1,   LC3II↑, 2,   lysoMP↑, 1,   lysosome↓, 1,   SESN2↑, 1,   TumAuto↓, 3,   TumAuto↑, 19,   TumAuto↝, 1,  

DNA Damage & Repair(tgid=10) ⓘ

ATM↑, 1,   DFF45↑, 1,   DNAdam↑, 22,   DNArepair↓, 1,   DNArepair↑, 1,   hTERT/TERT↓, 1,   P53↓, 3,   P53↑, 16,   P53↝, 3,   p‑P53↑, 1,   PARP↑, 4,   cl‑PARP↑, 8,   PCNA↓, 2,   RAD51↓, 1,   Telomerase↓, 4,   TOP1↓, 2,   TOP2↓, 1,   γH2AX↑, 4,  

Cell Cycle & Senescence(tgid=11) ⓘ

CDK1↓, 2,   CDK1↝, 1,   CDK2↓, 1,   CDK4↓, 4,   CDK6↓, 1,   CDK6↑, 1,   CHK1↓, 1,   CHK1↝, 1,   Cyc↓, 1,   cycA1/CCNA1↑, 1,   CycB/CCNB1↓, 3,   CycB/CCNB1↝, 1,   cycD1/CCND1↓, 6,   cycD1/CCND1↑, 2,   CycD3↓, 1,   cycE/CCNE↑, 1,   Ki-67↓, 4,   p19↑, 1,   P21↓, 1,   P21↑, 10,   p27/CDKN1B↓, 1,   p27/CDKN1B↑, 3,   p‑pRB↓, 1,   RB1↑, 1,   TumCCA↑, 48,   WEE1↑, 1,  

Proliferation, Differentiation & Cell State(tgid=12) ⓘ

p‑4E-BP1↓, 1,   ALDH↓, 2,   BMP2↑, 1,   CSCs↓, 10,   GH↓, 1,   HH↓, 5,   HH∅, 1,   IGF-1↓, 2,   IGFBP1↑, 1,   IGFBP3↑, 1,   Ki-67↓, 4,   NOTCH1↓, 2,   TumCG?, 1,   TumCG↓, 39,   TumCG↑, 2,   TumCP↓, 57,   TumCP↑, 2,   TumCP⇅, 1,   Wnt↓, 6,  

Migration(tgid=13) ⓘ

AntiAg?, 1,   AntiAg↑, 5,   AP-1↓, 2,   ATPase↓, 2,   CA↓, 1,   Ca+2↑, 14,   Ca+2↝, 4,   Cofilin↓, 1,   COL1↓, 1,   COL3A1↓, 1,   decorin↑, 1,   E-cadherin↓, 1,   E-cadherin↑, 7,   EMT↓, 13,   EMT↑, 1,   FAK↓, 5,   p‑FAK↓, 1,   fascin↓, 1,   ITGB1↓, 2,   ITGB6↓, 1,   KRAS↓, 1,   LEF1↓, 1,   MALAT1↓, 2,   MET↓, 2,   MMP1↓, 2,   MMP13↓, 1,   MMP2↓, 14,   MMP3↓, 1,   MMP7↓, 1,   MMP9↓, 13,   MMPs↓, 11,   N-cadherin↓, 3,   PDGF↓, 2,   Rho↓, 1,   Rho↝, 1,   ROCK1↓, 2,   Slug↓, 2,   Smad1↑, 1,   Snail↓, 3,   talin?, 1,   TGF-β↓, 5,   TIMP1↑, 3,   TSP-1↑, 1,   TumCA↓, 1,   TumCI↓, 20,   TumCI↑, 1,   TumCMig↓, 20,   TumCMig↑, 1,   TumMeta↓, 26,   Twist↓, 2,   uPA↓, 2,   UroPA↓, 1,   Vim↓, 5,   Vim↑, 1,   β-catenin/ZEB1↓, 7,  

Angiogenesis & Vasculature(tgid=14) ⓘ

angioG↓, 25,   angioG↑, 1,   CD31/PECAM-1↓, 1,   CD31/PECAM-1↑, 1,   ECM/TCF↓, 1,   EGR4↓, 1,   eNOS↑, 1,   HIF-1↓, 2,   HIF-1↑, 1,   Hif1a↓, 10,   Hif1a↑, 2,   Hypoxia↓, 1,   TXA2↓, 1,   VEGF↓, 16,   VEGFR2/KDR/Flk1↓, 4,  

Barriers & Transport(tgid=15) ⓘ

BBB↑, 2,   CellMemb↑, 3,   CTR1↝, 1,   CX43/GJA1↓, 1,   EPR↑, 10,   GLUT1↓, 3,   MMP↓, 27,   MMP↑, 2,   MPT↑, 2,   SLC12A5↝, 1,   sonoP↑, 2,   TJ↓, 1,   TRPM7↑, 2,   TRPV1↑, 1,   VGCC↑, 1,   ZO-1↓, 1,  

Immune & Inflammatory Signaling(tgid=16) ⓘ

CD155↓, 1,   CD25+↓, 1,   CD25+↑, 1,   CD4+↓, 2,   CD4+↑, 1,   CD44↓, 2,   CD47↓, 1,   CD8+↑, 3,   COX1↓, 2,   COX2/PTGS2↓, 16,   COX2/PTGS2↑, 1,   COX2/PTGS2↝, 1,   CXCL9↓, 1,   CXCR4↓, 1,   DCells↑, 1,   DR4↑, 3,   FOXP3↑, 1,   FoxP3+↓, 1,   GM-CSF↓, 1,   HCAR2↑, 2,   HLA↑, 1,   HLA-I/II↑, 1,   HMGB1↓, 1,   ICAM-1↓, 1,   IFN-γ↓, 3,   IFN-γ↑, 2,   IL1↓, 1,   IL1↑, 1,   IL10↓, 1,   IL10↑, 2,   IL12↑, 1,   IL1α↓, 1,   IL1β↓, 2,   IL2↓, 1,   IL2↑, 1,   IL4↓, 1,   IL6↓, 5,   IL6↑, 1,   IL8↓, 3,   IL8↑, 1,   Imm↑, 13,   Imm↝, 1,   INF-γ↝, 1,   Inflam↓, 10,   Inflam↑, 1,   IP-10/CXCL-10↓, 1,   Macrophages↓, 1,   MCP1/CCL2↓, 2,   MCT1↓, 1,   MIP-1β↓, 1,   Neut↓, 1,   Neut↑, 1,   NF-kB↓, 27,   NF-kB↑, 1,   NK cell↑, 5,   NK cell⇅, 1,   PD-L1↓, 2,   PGE2↓, 6,   PSA↓, 4,   RAGE↓, 1,   T-Cell↑, 3,   TLR2↓, 1,   TLR4↓, 1,   TNF-α↓, 7,   TNF-α↑, 1,   VitD↑, 1,  

Cellular Microenvironment(tgid=17) ⓘ

GGT/CD224↓, 1,   pH∅, 1,   e-pH↓, 1,   e-pH↑, 1,   i-pH↓, 1,   Temp↓, 1,   Temp∅, 1,  

Synaptic & Neurotransmission(tgid=18) ⓘ

BDNF↓, 1,   GABA↑, 1,   TrkB↓, 1,  

Protein Aggregation(tgid=19) ⓘ

PSEN1/PS1↓, 1,  

Hormonal & Nuclear Receptors(tgid=20) ⓘ

6IL↑, 1,   AR↓, 1,   AR↝, 1,   CYP24A1↓, 1,   ER-α36↓, 1,   PPARα↓, 1,   PPARγ↑, 1,   testos∅, 1,  

Drug Metabolism & Resistance(tgid=21) ⓘ

ABCG2↓, 1,   BioAv↓, 13,   BioAv↑, 20,   BioAv↝, 8,   BioEnh↑, 1,   chemoR↓, 1,   ChemoSen↓, 4,   ChemoSen↑, 47,   ChemoSen∅, 1,   CompStab↓, 2,   CYP1A1↓, 2,   CYP1A1↑, 1,   CYP1A2↓, 1,   CYP1A2↑, 1,   CYP2A3/CYP2A6↓, 1,   CYP2E1↑, 1,   CYP3A4↓, 1,   CYP3A4⇅, 1,   DDS↑, 6,   Dose?, 3,   Dose↓, 5,   Dose↑, 9,   Dose↝, 67,   Dose∅, 3,   eff↓, 27,   eff↑, 95,   eff⇅, 1,   eff↝, 21,   eff∅, 2,   GSTM1↑, 1,   GSTZ1↓, 1,   Half-Life↓, 4,   Half-Life↑, 4,   Half-Life↝, 3,   MDR1↓, 1,   P-gp/ABCB1↓, 7,   P450↓, 4,   RadioS↓, 1,   RadioS↑, 14,   RadioS↝, 1,   selectivity?, 1,   selectivity↑, 44,   selectivity∅, 1,   Synergy↑, 32,   TET2↑, 1,  

Clinical Biomarkers(tgid=22) ⓘ

ALAT↓, 3,   ALB↑, 1,   ALP↓, 1,   anemia↓, 1,   AR↓, 1,   AR↝, 1,   AST?, 1,   AST↓, 2,   BloodF↓, 1,   BloodF↑, 1,   BMD↑, 1,   BUN↓, 1,   CA125∅, 1,   CIT↓, 1,   creat↓, 1,   CTC↓, 1,   DBIL↓, 1,   EGFR↓, 11,   EZH2↓, 1,   Ferritin↑, 1,   Hcy/homoC↓, 2,   Hcy/homoC↝, 1,   HER2/EBBR2↓, 4,   hTERT/TERT↓, 1,   IBIL↓, 1,   IL6↓, 5,   IL6↑, 1,   KRAS↓, 1,   LDH↝, 1,   Myc↓, 1,   NOS2↓, 1,   PC↑, 2,   PD-L1↓, 2,   PSA↓, 4,   RAGE↓, 1,   RBC↑, 1,   TBIL↓, 1,   TF-Ag↓, 1,   Verbal↑, 1,   VitD↑, 1,   WBC↑, 1,  

Functional Outcomes(tgid=23) ⓘ

AntiAge↑, 1,   AntiCan↓, 3,   AntiCan↑, 31,   AntiDiabetic↑, 1,   antiNeop↑, 3,   AntiTum↓, 1,   AntiTum↑, 15,   Appetite↑, 1,   cardioP↑, 2,   chemoP↑, 18,   chemoPv↑, 7,   ChemoSideEff↓, 2,   cognitive?, 1,   cognitive↑, 3,   DCR↑, 1,   fatigue↓, 1,   hepatoP↑, 4,   hepatoP∅, 1,   memory↑, 1,   Mucositis↓, 1,   MusCon↓, 2,   Nausea↓, 1,   neuroP↑, 3,   NP/CIPN↓, 1,   NP/CIPN↑, 1,   Obesity↑, 1,   OS?, 1,   OS↑, 18,   OS∅, 1,   Pain↓, 1,   PDE4↓, 1,   PFS↑, 3,   Pin1↓, 1,   QoL↑, 9,   radioP?, 1,   radioP↑, 4,   Remission↑, 2,   RenoP↑, 2,   Risk↓, 25,   Risk↑, 6,   Risk↝, 2,   Risk∅, 1,   Sleep↑, 1,   toxicity↓, 19,   toxicity↑, 3,   toxicity⇅, 1,   toxicity↝, 13,   toxicity∅, 1,   TumVol↓, 11,   TumVol↑, 1,   TumW↓, 4,   Vomit↓, 1,   Weight↑, 2,   Weight∅, 1,   Wound Healing↑, 2,  

Infection & Microbiome(tgid=24) ⓘ

GutMicro↑, 5,   Inf↓, 1,   Inf↑, 1,   Sepsis↓, 1,   Sepsis↑, 1,  

Ingredients & Constituents(tgid=25) ⓘ

Api↑, 1,   Ingr?, 1,  
Total Targets: 680

Pathway results for Effect on Normal Cells:


Redox & Oxidative Stress(tgid=1) ⓘ

4-HNE↓, 1,   antiOx↓, 6,   antiOx↑, 79,   Catalase↑, 25,   Fenton↓, 1,   GPx↑, 17,   GPx∅, 1,   GPx1↑, 4,   GPx4↑, 6,   GSH↓, 2,   GSH↑, 29,   GSH∅, 1,   GSR↓, 1,   GSR↑, 4,   GSTs↑, 5,   H2O2↓, 4,   H2O2↑, 1,   HDL↓, 1,   HDL↑, 5,   HDL∅, 1,   HNE↓, 1,   HO-1↓, 1,   HO-1↑, 15,   Iron↓, 2,   Iron↑, 1,   Keap1↓, 3,   lipid-P↓, 28,   MDA↓, 22,   MDA↑, 1,   MPO↓, 4,   NADH↓, 1,   NRF2↑, 28,   Prx↑, 1,   RNS↓, 3,   ROS?, 1,   ROS↓, 89,   ROS↑, 4,   ROS⇅, 1,   ROS∅, 2,   mt-ROS↓, 1,   mt-ROS↑, 1,   selenoP↑, 5,   SOD↓, 2,   SOD↑, 34,   SOD1↓, 1,   SOD1↑, 5,   SOD2↑, 3,   TAC↑, 3,   TBARS↓, 2,   Trx↑, 1,   VitC↑, 2,  

Metal & Cofactor Biology(tgid=2) ⓘ

IronCh↑, 5,   Zn2+↓, 1,  

Mitochondria & Bioenergetics(tgid=3) ⓘ

compI↑, 1,   compII↑, 1,   compIII↑, 1,   compV↑, 1,   ETC↝, 2,   Insulin↓, 1,   Insulin↑, 2,   Insulin↝, 1,   mitResp↓, 1,   mitResp↑, 2,   mtDam↓, 1,   OCR↑, 2,   mt-OCR↑, 1,   OXPHOS↓, 1,   SIRT3↑, 1,  

Core Metabolism/Glycolysis(tgid=4) ⓘ

5LO↓, 7,   ACLY∅, 1,   adiP↓, 1,   adiP↑, 1,   ALAT↓, 6,   ALAT∅, 1,   AMPK↑, 2,   ATP↑, 8,   cAMP↑, 2,   Cit/L-Cit↝, 1,   DHA↑, 1,   ECAR↑, 1,   ECAR∅, 1,   G6PD↑, 1,   glucose↓, 2,   glucose↝, 1,   GlucoseCon↑, 1,   GlutMet↑, 1,   Glycolysis↑, 1,   GSK‐3β↓, 3,   GSK‐3β↑, 2,   H2S↑, 1,   HK2↑, 1,   KeyT↑, 1,   LDL↓, 15,   NADPH↓, 2,   NADPH↑, 2,   ODC1↝, 1,   PFKL↑, 1,   PFKM↑, 1,   PGC1A↑, 1,   PKM2↑, 1,   polyA↝, 1,   SCFAs∅, 1,   SIRT1↑, 6,   SIRT2↑, 1,  

Cell Death(tgid=5) ⓘ

AIF↓, 2,   Apoptosis↓, 9,   BAX↓, 1,   BAX↑, 1,   Bcl-2↑, 2,   Bcl-xL↓, 1,   Casp1↓, 1,   Casp12↓, 1,   Casp3↓, 4,   cl‑Casp3↓, 1,   proCasp3↓, 1,   Casp6↓, 1,   Casp9↓, 3,   Cyt‑c↓, 1,   Cyt‑c↑, 1,   Ferroptosis↓, 3,   GranB/GZMB↓, 1,   HEY1↑, 1,   iNOS↓, 9,   iNOS↑, 1,   necrosis↓, 1,   p38↓, 1,   p38↑, 1,  

Kinase & Signal Transduction(tgid=6) ⓘ

Akt↓, 3,   Akt↑, 6,   CREB↑, 1,   ERK↓, 1,   ERK↑, 2,   p‑ERK↓, 1,   p‑ERK↑, 1,   HCAR2↑, 1,   IGF-1R↓, 1,   IKKα↓, 1,   JAK↓, 1,   JNK↓, 2,   JNK↑, 1,   p‑JNK↓, 1,   p‑JNK↑, 1,   MAPK↓, 1,   MAPK↑, 1,   MAPK↝, 1,   p‑MEK↑, 1,   mTOR↓, 2,   mTOR↑, 2,   p‑mTOR↓, 1,   p‑P70S6K↑, 1,   PDGFR-BB↓, 1,   PI3K↓, 3,   PI3K↑, 4,   PKCδ↓, 1,   PKCδ↑, 3,   PTEN↓, 1,   STAT↓, 1,   STAT3↓, 3,   STAT3↑, 1,  

Transcription & Epigenetics(tgid=7) ⓘ

AntiThr↑, 1,   ATF4↓, 2,   cJun↓, 1,   FOXO3↑, 1,   H3K9↓, 1,   HDAC↓, 1,   HDAC2↓, 1,   other?, 24,   other↓, 71,   other↑, 132,   other⇅, 2,   other↝, 181,   other∅, 6,   SOX9↑, 2,   SUV39H↓, 1,   tumCV↑, 1,  

Protein Folding & ER Stress(tgid=8) ⓘ

CHOP/DDIT3↓, 3,   CHOP/DDIT3↑, 1,   p‑eIF2α↓, 1,   cl‑eIF2α↑, 1,   ER Stress↓, 5,   ER Stress↑, 1,   GRP78/BiP↓, 1,   GRP78/BiP↑, 1,   HSP70/HSPA5↓, 1,   HSP70/HSPA5↑, 1,   HSPs↑, 1,   PERK↓, 1,   p‑PERK↑, 1,   UPR↓, 1,   XBP-1↓, 1,  

Autophagy & Lysosomes(tgid=9) ⓘ

Beclin-1/ATG6↓, 1,   LC3‑Ⅱ/LC3‑Ⅰ↓, 1,   LC3‑Ⅱ/LC3‑Ⅰ↑, 1,   LC3II↓, 1,  

DNA Damage & Repair(tgid=10) ⓘ

DNAdam↓, 5,   DNArepair↑, 1,   P53↓, 1,   P53↑, 2,   PCNA↓, 1,   PCNA↑, 1,  

Cell Cycle & Senescence(tgid=11) ⓘ

cycD1/CCND1↓, 1,   E2Fs↑, 1,   P21↑, 1,   TumCCA↑, 1,  

Proliferation, Differentiation & Cell State(tgid=12) ⓘ

BMPs↑, 1,   Choline↑, 1,   Diff↑, 2,   Diff↝, 1,   FGF↑, 1,   GH↑, 1,   HH↓, 1,   IGF-1↑, 1,   IGFBP1↑, 1,   MSCs↑, 1,   NOTCH↑, 1,   TumCG↓, 1,   Zn2+↓, 1,  

Migration(tgid=13) ⓘ

AntiAg↓, 1,   AntiAg↑, 14,   AntiAg∅, 1,   AP-1↓, 3,   Ca+2↓, 5,   Ca+2↑, 4,   Ca+2↝, 3,   cal2↓, 1,   COL1↓, 1,   COL2A1↑, 2,   F-actin↑, 1,   FAK↑, 1,   MMP2↓, 1,   MMP2↑, 1,   MMP3↓, 1,   MMP9↓, 5,   MMPs↓, 2,   proline↝, 1,   Rho↓, 2,   ROCK1↓, 1,   p‑SMAD2↓, 1,   p‑SMAD3↓, 1,   TGF-β↓, 1,   TGF-β↑, 4,   TumCMig↑, 1,   TXNIP↓, 1,  

Angiogenesis & Vasculature(tgid=14) ⓘ

angioG↓, 1,   angioG↑, 4,   angioG↝, 1,   E-sel↓, 2,   Hif1a↓, 3,   Hif1a↑, 1,   Hif1a↝, 1,   Hif1a∅, 1,   Hypoxia↓, 1,   NO↓, 13,   NO↑, 2,   TXA2↓, 2,   VEGF↓, 3,   VEGF↑, 3,  

Barriers & Transport(tgid=15) ⓘ

BBB?, 1,   BBB↓, 2,   BBB↑, 14,   BBB↝, 3,   CellMemb↑, 2,   CLDN1↓, 1,   CLDN1↑, 1,   CX43/GJA1↑, 1,   EPR↑, 2,   GastroP↑, 3,   GLUT1↑, 2,   GLUT3↑, 1,   IBI↑, 1,   MMP↑, 5,   MUC5AC↓, 1,   THBD↑, 1,   TJ↓, 1,   TRPM7↓, 1,   TRPV3↑, 2,   VGCC↓, 1,   ZO-1↓, 1,   ZO-1↑, 2,  

Immune & Inflammatory Signaling(tgid=16) ⓘ

CB2 / CNR2↑, 1,   CCL11↓, 1,   CD25+↓, 1,   CD4+↑, 2,   CD69↓, 1,   CD8+↑, 1,   COX1↓, 9,   COX2/PTGS2↓, 23,   CTLA-4↓, 1,   CXCR4↓, 1,   FOXP3↑, 1,   HCAR2↑, 1,   IFN-γ↓, 3,   IL1↓, 1,   IL10↑, 6,   IL17↓, 4,   IL18↓, 1,   IL1β↓, 21,   IL2↓, 3,   IL22↓, 1,   IL23↓, 1,   IL4↓, 5,   IL6↓, 29,   IL6↑, 1,   IL8↓, 4,   Imm↑, 14,   INF-γ↓, 1,   Inflam?, 1,   Inflam↓, 100,   Inflam↑, 2,   LPS↓, 1,   MCP1/CCL2↓, 2,   MCP1/CCL2↑, 1,   NeuroI↓, 1,   NF-kB↓, 21,   NF-kB↑, 1,   p‑NF-kB↓, 2,   NK cell↑, 1,   NLRP3↓, 5,   NLRP3↑, 1,   p65↓, 1,   PGE2↓, 9,   PSA↓, 1,   TLR3↓, 1,   TLR4↓, 4,   TNF-α↓, 32,  

Cellular Microenvironment(tgid=17) ⓘ

ADAM17↑, 1,   GFAP↓, 1,   pH↑, 1,   pH↝, 1,  

Synaptic & Neurotransmission(tgid=18) ⓘ

5-AR↓, 1,   5HT↓, 2,   5HT↑, 3,   Ach?, 1,   Ach↑, 7,   AChE↓, 16,   AChE∅, 1,   BChE↓, 6,   BDNF↑, 11,   BDNF∅, 1,   BrainVol↑, 1,   BrainVol↝, 1,   BrainVol∅, 1,   CARTPT↑, 1,   ChAT↑, 1,   GABA↑, 3,   MAOA↓, 2,   MAOA↑, 1,   MAOB↓, 1,   monoA↑, 1,   NTF3/NT-3↑, 1,   PSD95?, 1,   SYN1↑, 1,   SYT1↑, 1,   TrkB↓, 1,   TrkB↑, 1,   β-Endo↑, 1,  

Protein Aggregation(tgid=19) ⓘ

APP↓, 3,   Aβ↓, 21,   Aβ↑, 1,   Aβ∅, 1,   Aβ42↓, 1,   BACE/β-secretase↓, 6,   tau↓, 8,   p‑tau↓, 8,   XO↓, 1,  

Hormonal & Nuclear Receptors(tgid=20) ⓘ

CYP19↓, 1,   GPER↑, 1,   GR↑, 1,   PPARα↑, 2,   testos↑, 1,  

Drug Metabolism & Resistance(tgid=21) ⓘ

ABC↓, 1,   BioAv↓, 16,   BioAv↑, 43,   BioAv⇅, 2,   BioAv↝, 24,   BioEnh↑, 3,   CompStab↑, 3,   CYP2C6↓, 1,   CYP2E1↓, 1,   CYP3A2↓, 1,   CYP3A4↓, 1,   CYP3A4↑, 1,   Dose?, 3,   Dose↓, 4,   Dose↑, 7,   Dose⇅, 1,   Dose↝, 60,   Dose∅, 1,   eff↓, 9,   eff↑, 50,   eff↝, 12,   GSTA1↑, 1,   Half-Life↓, 7,   Half-Life↑, 5,   Half-Life↝, 14,   MRP1/ABCC1↓, 1,   P-gp/ABCB1↓, 2,   P-gp/ABCB1↑, 1,   P450↓, 1,   selectivity↑, 1,   Synergy↑, 21,   TET2↑, 1,  

Clinical Biomarkers(tgid=22) ⓘ

ALAT↓, 6,   ALAT∅, 1,   ALB↑, 1,   ALP↑, 1,   AST↓, 5,   AST∅, 1,   BloodF↑, 2,   BMD↑, 5,   BP↓, 11,   BP∅, 1,   BUN↑, 1,   Calcium↝, 1,   creat↓, 3,   creat↑, 2,   CRP↓, 5,   Hcy/homoC↓, 7,   Hcy/homoC↝, 1,   IL6↓, 29,   IL6↑, 1,   IRes↓, 1,   KeyT↑, 1,   LDH↓, 4,   NOS2↓, 2,   PSA↓, 1,   PV↓, 1,   TMAO↑, 1,   UFR?, 1,   UFR↑, 2,   UR↓, 1,   Urea↓, 1,  

Functional Outcomes(tgid=23) ⓘ

AntiAge↑, 5,   antiAll↑, 6,   AntiArt↑, 3,   AntiCan↑, 9,   AntiDiabetic↓, 1,   AntiDiabetic↑, 15,   antiPs↑, 1,   AntiTum↑, 1,   BOLD↑, 1,   Bone Healing↑, 1,   BowelM↑, 1,   cardioP↓, 1,   cardioP↑, 22,   cardioP∅, 1,   chemoP↑, 5,   chemoPv↑, 4,   cognitive↓, 4,   cognitive↑, 83,   cognitive↝, 2,   cognitive?, 1,   cognitive∅, 3,   DCR∅, 1,   diuretic↑, 1,   fatigue↓, 1,   hepatoP↓, 1,   hepatoP↑, 18,   IPSS↓, 1,   IPSS↝, 1,   memory↓, 1,   memory↑, 42,   memory∅, 1,   Mood↑, 8,   motorD↑, 6,   neuroP↓, 1,   neuroP↑, 67,   Obesity↓, 7,   ORR∅, 1,   OS↑, 2,   Pain↓, 9,   PFS∅, 1,   QoL↑, 5,   radioP↑, 4,   RenoP↑, 5,   Risk↓, 25,   Risk↑, 4,   Risk↝, 1,   Risk∅, 1,   Sleep↑, 6,   Strength↑, 1,   Stress↓, 2,   Stroke↓, 5,   toxicity?, 2,   toxicity↓, 50,   toxicity↑, 4,   toxicity⇅, 1,   toxicity↝, 8,   toxicity∅, 5,   Weight↓, 1,   Weight↑, 1,   Weight↝, 1,   Wound Healing↓, 1,   Wound Healing↑, 8,  

Infection & Microbiome(tgid=24) ⓘ

AntiBio↑, 9,   AntiFungal↑, 7,   AntiP↑, 1,   AntiViral↑, 4,   Bacteria↓, 24,   Diar↓, 2,   GutMicro↑, 20,   GutMicro↝, 4,   GutMicro∅, 1,   Sepsis↓, 5,  

Ingredients & Constituents(tgid=25) ⓘ

Api↑, 1,   CA↑, 1,   Catechins↑, 1,   FA↑, 1,   Fibre↑, 1,   GA↑, 1,   Ingr?, 1,   Ingr↑, 2,   LT↑, 1,   Myr↑, 1,   Phen↑, 1,   Poly↑, 1,   QC↑, 2,  
Total Targets: 517

Scientific Paper Hit Count for: other, other
38 Magnetic Fields
27 Silver-NanoParticles
22 Vitamin C (Ascorbic Acid)
17 Folic Acid, Vit B9
13 Vitamin B12
12 Selenium
12 Selenite (Sodium)
11 Hydrogen Gas
11 Selenium NanoParticles
10 Chemotherapy
10 chitosan
10 Curcumin
10 EGCG (Epigallocatechin Gallate)
9 Allicin (mainly Garlic)
9 Gamma-aminobutyric acid
9 Resveratrol
8 Vitamin E
8 Aspirin
8 Sulforaphane (mainly Broccoli)
8 Choline
8 Coenzyme Q10
8 Quercetin
8 Laetrile B17 Amygdalin
8 Taurine
7 Radiotherapy/Radiation
7 Boron
7 Graviola
7 itraconazole
7 Magnetic Field Rotating
6 Alpha-Lipoic-Acid
6 Lutein
6 Vitamin B6,pyridoxine
6 Silicic Acid
6 Germanium Organic/Ge-132 / propagermanium (organogermanium)
6 HydroxyCitric Acid
6 Potassium
5 borneol
5 Carvacrol
5 Vitamin K2
5 Rosmarinic acid
5 D-limonene
5 Electrical Pulses
5 Exercise
5 Flaxseed/Linseed
5 SDG/lignans
5 Magnesium
5 Melatonin
5 Vitamin B5,Pantothenic Acid
5 Whole Body Vibration
4 2-DeoxyGlucose
4 5-Hydroxytryptophan
4 Copper and Cu NanoParticles
4 Citric Acid
4 Anti-oxidants
4 Aromatherapy
4 Artemisinin
4 Zeaxanthin
4 probiotics
4 Broccoli
4 Butyrate
4 Chlorogenic acid
4 Cynara scolymus/Globe Artichoke/Artichoke Extract
4 Piperine
4 Dandelion Root
4 Ginkgo biloba-EGb 761
4 Emodin
4 Fisetin
4 phytic acid, Inositol hexakisphosphate
4 Luteolin
4 Magnolol
4 Shikonin
4 Vitamin D3
3 Astragalus
3 Ginseng
3 Ginger/6-Shogaol/Gingerol
3 Lycopene
3 Phyllanthus emblica/Emblica officinalis/Amla / Indian Gooseberry
3 Apigenin (mainly Parsley)
3 Berberine
3 Bufalin/Huachansu
3 Bacopa monnieri
3 Capsaicin
3 Celastrol
3 chaetocin
3 Polyphenols
3 Diclofenac
3 diet Methionine-Restricted Diet
3 Echinacea
3 Eugenol
3 Garcinol
3 Genistein (soy isoflavone)
3 Inositol
3 iodine
3 Kaempferol
3 Lactobacillus
3 Lactoferrin/Talactoferrin
3 Methylene blue
3 Phenylbutyrate
3 Terpinen-4-ol / Tea Tree Oil
3 Vitamin B1/Thiamine
2 Auranofin
2 Akkermansia
2 immunotherapy
2 Aluminum
2 Ashwagandha(Withaferin A)
2 Ascorbyl Palmitate
2 Atorvastatin
2 Dipyridamole
2 Baicalein
2 Biochanin A
2 bempedoic acid
2 beta-carotene(VitA)
2 Vitamin B3,Niacin
2 brusatol
2 buckwheat sprouts
2 Carnosic acid
2 Caffeic acid
2 Cannabidiol
2 chemodynamic therapy
2 Cinnamon
2 Crocetin
2 CUSP9
2 Dichloroacetate
2 Date Fruit Extract
2 Docosahexaenoic Acid
2 diet Short Term Fasting
2 Dimethyl Sulfoxide
2 Ellagic acid
2 5-fluorouracil
2 ferumoxytol
2 Geldanamycin
2 Flickering Light Stimulation
2 Formononetin
2 Shilajit/Fulvic Acid
2 Ginkgolic acids
2 Ginkgo biloba
2 Germanium inorganic
2 Gossypol/AT-101
2 Grapeseed extract
2 Hibiscus sabdariffa
2 Hyperthermia
2 Indole-3-carbinol
2 Inulin Prebiotic
2 Juglone
2 Licochalcone A
2 Lecithin
2 mebendazole
2 MCT oil
2 Methyl salicylate / Sweet Birch oil
2 Nimbolide
2 Oxygen, Hyperbaric
2 Peppermint
2 Phenethyl isothiocyanate
2 Phenolic Acids
2 Piperlongumine
2 Phosphatidylserine
2 salinomycin
2 S-adenosyl-L-methionine
2 SonoDynamic Therapy UltraSound
2 Silymarin (Milk Thistle) silibinin
2 Thymoquinone
1 Cisplatin
1 5-Aminolevulinic acid
1 Photodynamic Therapy
1 Serotonin, 5-hydroxytryptamine
1 dietMediterranean
1 Annona atemoya Seed Extract
1 acetaminophen
1 Anthocyanins
1 Omeprazole
1 Gold NanoParticles
1 Ajoene (compound of Garlic)
1 Acetyl-l-carnitine
1 alpha Linolenic acid
1 γ-linolenic acid (Borage Oil)
1 Anethole/trans-Anethole
1 Vitamin A, Retinoic Acid
1 Paclitaxel/Taxol
1 Aloe anthraquinones
1 Beta-Caryophyllene
1 Bevacizumab (brand Avastin)
1 Bifidobacterium
1 Brucea javanica
1 Bromelain
1 Bortezomib
1 Bruteridin(bergamot juice)
1 α-Bisabolol / Chamomile oil
1 Caffeic Acid Phenethyl Ester (CAPE)
1 Carnosine
1 Catechins
1 Chlorophyllin
1 Chocolate
1 Chyawanprash
1 Carica papaya leaf extract
1 Camptothecin
1 irinotecan
1 Cyclopamine
1 Cynaropicrin
1 Cysteamine
1 Dasatinib/Phyrago
1 Deguelin
1 Dihydrocaffeic Acid
1 diet Fermented Foods
1 diet FMD Fasting Mimicking Diet
1 Disulfiram
1 doxorubicin
1 Eurycomanone
1 Ferulic acid
1 Radicicol/monorden
1 flavonoids
1 Flaxseed Oil
1 Geraniol
1 Ginkgolide B
1 hydrogen sulfide
1 Calorie Restriction Mimetics
1 Spermidine
1 Hydroxycinnamic-acid
1 hydroxychloroquine
1 High-Ozonide Oil
1 Isoliquiritigenin
1 Licorice
1 isoflavones
1 isoquercitrin
1 Ivermectin
1 Isovitexin
1 L-ornithine
1 Lemongrass Extract/Citral
1 Myricetin
1 Matrine
1 metronomic chemo
1 Methyl Jasmonate
1 methylseleninic acid
1 Metformin
1 Methylglyoxal
1 Lemon Balm/Melissa officinalis
1 Mushroom Lion’s Mane
1 nicotinamide adenine dinucleotide
1 Bicarbonate(Sodium)
1 Naringin
1 Rutin
1 Oregano
1 Propolis -bee glue
1 Parthenolide
1 Pterostilbene
1 Pumpkin Seed Oil / Cucurbita pepo
1 Tamsulosin
1 Ramucirumab (CYRAMZA)
1 Echistatin
1 Radio Frequency
1 EMF
1 Sulfasalazine
1 Shankhpushpi
1 Thyme
1 Thymol-Thymus vulgaris
1 Urolithin
1 glucose deprivation
1 Zinc
Query results interpretion may depend on "conditions" listed in the research papers.
Such Conditions may include : 
  -low or high Dose
  -format for product, such as nano of lipid formations
  -different cell line effects
  -synergies with other products 
  -if effect was for normal or cancerous cells

Filter Conditions: Pro/AntiFlg:%  IllCat:%  CanType:%  Cells:%  prod#:%  Target#:767  State#:%  Dir#:%
  wNotes=0  sortOrder:rid,rpid

 

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