BioAv Cancer Research Results

BioAv, bioavailability: Click to Expand ⟱
Source:
Type: measurement
Bioavailability (usually in %) absorbed by the body.
Scientific Papers found: Click to Expand⟱
6015- CGA,    Chlorogenic acid bioavailability largely depends on its metabolism by the gut microflora in rats
- in-vivo, Nor, NA
*BioAv↝,
6003- CGA,    Bioavailability and metabolism of chlorogenic acids (acyl-quinic acids) in humans
- Review, Nor, NA
*AntiDiabetic↑, *BioAv↑,
6004- CGA,    Dose-response plasma appearance of coffee chlorogenic and phenolic acids in adults
- Human, Nor, NA
*BioAv↝, *other↝, BioAv↓,
6013- CGA,    Advances in Pharmacological Properties, Molecular Mechanisms, and Bioavailability Strategies of Chlorogenic Acid in Cardiovascular Diseases Therapy
- Review, CardioV, NA
*BioAv↝, *BioAv↝, *BP↓, *ROS↓, *NADPH↓, *AntiAg↑, *TXA2↓, *antiOx↑, *cardioP↑, *Inflam↓, *SOD↑, *Catalase↑, *Ferroptosis↓, *NF-kB↓, *JNK↓, *NRF2↑, *HO-1↑, *toxicity↓, *BioAv↓, *BioAv↑, *BioAv↑, eff↑,
6007- CGA,    A Comprehensive View on the Impact of Chlorogenic Acids on Colorectal Cancer
- Review, CRC, NA
antiOx↑, TumCCA↑, Apoptosis↑, Wnt↝, PI3K↝, MAPK↝, ROS↓, BioAv↝, P53↑, P21↑, CDK1↑, Ki-67↓, Ca+2↑, p‑Akt↓, mTOR↓, GSH↑, NRF2↑, HO-1↑, COX2↓, TNF-α↓, IL1β↓, IL6↓,
6009- CGA,    Chlorogenic Acid: An In-Depth Review of Its Effectiveness in Cancer Treatment
- Review, Var, NA
TumCCA↑, TumCI↓, TumMeta↓, angioG↓, ROS↑, ChemoSen↑, BioAv↓, Half-Life↓, PI3K↓, Akt↓, mTOR↓, Apoptosis↑, NOTCH↓, Hif1a↓, VEGF↓, Casp3↑, MMP↓, Ferroptosis↑, ATP↓,
6010- CGA,    The Biological Activity Mechanism of Chlorogenic Acid and Its Applications in Food Industry: A Review
- Review, Nor, NA
*antiOx↑, *hepatoP↑, *RenoP↑, AntiTum↑, *glucose↝, *Inflam↓, *neuroP↑, *ROS↓, *Keap1↓, *NRF2↑, *SOD↑, *Catalase↑, *GPx↑, *GSH↑, *MDA↓, *p‑ERK↑, *GRP78/BiP↑, *CHOP↑, *GRP94↑, *Casp3↓, *Casp9↓, *HGF/c-Met↑, *TNF-α↓, *TLR4↓, *MAPK↓, *IL1β↓, *iNOS↓, TCA↓, Glycolysis↓, Bcl-2↓, BAX↑, MAPK↑, JNK↑, CSCs↓, Nanog↓, SOX2↓, CD44↓, OCT4↓, P53↑, P21↑, *SOD1↑, *AGEs↓, *GLUT2↑, *HDL↑, *Fas↓, *HMG-CoA↓, *NF-kB↓, *HO-1↓, *COX2↓, *TLR4↓, *BioAv↑, *BioAv↝, TumCP↓, TumCMig↓, TumCI↓,
6011- CGA,    Chlorogenic Acid’s Role in Metabolic Health: Mechanisms and Therapeutic Potential
- Review, Nor, NA
*BioAv↓, *antiOx↑, *Inflam↓, *Bacteria↓, *hepatoP↑, *cardioP↑, *neuroP↑, *ROS↓, *NF-kB↓, *NRF2↑, *Obesity↓, *GutMicro↑, *AntiAg↑, *cardioP↑, *AntiDiabetic↑, *NLRP3↓, *OCLN↓, *VEGF↓, BioAv↝,
6037- CGA,    Pharmacokinetics and brain penetration study of chlorogenic acid in rats
- in-vivo, AD, NA - in-vivo, Stroke, NA
*Dose↝, *eff↑, *BioAv↑, *eff↑,
6043- CGA,  SeNPs,    Enhanced Effect of Combining Chlorogenic Acid on Selenium Nanoparticles in Inhibiting Amyloid β Aggregation and Reactive Oxygen Species Formation In Vitro
- in-vitro, AD, NA
*ROS↓, *Aβ↓, *BioAv↝, *BioAv↑, *Dose↝, *ROS↓, *H2O2↓, *toxicity↓,
6045- CGA,  SeNPs,    A Flower-like Brain Targeted Selenium Nanocluster Lowers the Chlorogenic Acid Dose for Ameliorating Cognitive Impairment in APP/PS1 Mice
- in-vivo, AD, NA
*neuroP↑, *BioAv↑, *GutMicro↑, *BBB↑, *Aβ↓, *glucose↝,
6029- CGA,    Pharmacokinetics of chlorogenic acids absorbed in human plasma and their metabolites following oral ingestion of coffee drink
- Trial, Nor, NA
*Dose↝, *BioAv↑, *Half-Life↝,
6028- CGA,    Chlorogenic acids from green coffee extract are highly bioavailable in humans
- Trial, Nor, NA
*BioAv↑, *Dose↝,
6026- CGA,    Chlorogenic Acid: The Conceivable Chemosensitizer Leading to Cancer Growth Suppression
- Review, Var, NA
ChemoSen↑, AMPK↑, EGFR↓, PI3K↓, mTOR↓, Hif1a↓, VEGF↓, MAPK↓, ERK↓, DNAdam↑, TOP1↓, TOP2↓, Apoptosis↑, *BioAv↝, *Half-Life↓,
6023- CGA,    Pharmacological advances of the chlorogenic acids family: current insights and future research directions
- Review, AD, NA - Review, Park, NA - Review, IBD, NA
*Aβ↓, *neuroP↑, *cardioP↑, *GastroP↑, *RenoP↑, *hepatoP↑, *Obesity↓, *Bacteria↓, *BioAv↑, *BioAv↑, *BioAv↑, *ROS↓, *GutMicro↑, *IBI↑, *MCT1↓, *NF-kB↓, *DNMT1↓,
6025- Chit,    Glycated chitosan as a new non-toxic immunological stimulant
- vitro+vivo, Var, HeLa
*Imm↑, *BioAv↑, eff↑, *toxicity↓, *TNF-α↑, *Obesity↓,
6000- Chit,    Chitosan in Modern Pharmacotherapy: From Drug Encapsulation to Targeted Delivery Systems
- Review, Var, NA
DDS↑, toxicity↓, TJ↓, BioAv↑, *Bacteria↓, *Inflam↓, *antiOx↓, Wound Healing↑, other↝, eff↑, eff↑,
5981- Chit,    Chitosan-Based Drug Delivery Systems for Targeted Chemotherapy in Colorectal Cancer: A Scoping Review
- Review, CRC, NA
DDS↑, eff↑, BioAv↑, BioEnh↑, eff↑,
5982- Chit,    Chitosan Nanoparticles-Based Cancer Drug Delivery: Application and Challenges
- Review, Var, NA
DDS↑, antiOx↑, Bacteria↓, AntiTum↑, Half-Life↑, BioAv↑, toxicity↓,
5983- Chit,    Chitosan-Based Nano-Smart Drug Delivery System in Breast Cancer Therapy
- Review, BC, NA
DDS↑, BioAv↑, EPR↑, TumCP↓, angioG↓, TumMeta↓, other↑,
5984- Chit,    Chitosan in cancer therapy: a dual role as a therapeutic agent and drug delivery system
- Review, Var, NA
DDS↑, BioAv↑, TumCP↓, angioG↓, TumMeta↓, Apoptosis↑, eff↑,
5987- Chit,    Chitin, Chitosan, and Glycated Chitosan Regulate Immune Responses: The Novel Adjuvants for Cancer Vaccine
- Review, Var, NA
other↝, other↝, *Weight↝, *toxicity↓, *Bacteria↓, *BioAv↑, DDS↑, *Wound Healing↑, *other↝, *Imm↑, eff↑, *BioAv↝, *BioAv↑, eff↑, NK cell↑, IL2↑, IFN-γ↑, IL10↑,
5991- Chit,    Chitosan-Based Nanoencapsulated Essential Oils: Potential Leads against Breast Cancer Cells in Preclinical Studies
- Review, BC, NA
*other↝, *BioAv↓, eff↑, toxicity↓, eff↑, TumCD↑, Half-Life↑, selectivity↑, EPR↑, ROS↑, Apoptosis↑, eff↑,
5996- Chit,    NEW CHITOSAN-BASED CHEMO PHARMACEUTICAL DELIVERY SYSTEMS FOR TUMOR CANCER TREATMENT: SHORT-REVIEW
- Review, Var, NA
BioAv↑, Wound Healing↑, DDS↑, toxicity↓, eff↑,
5994- Chit,    Anticancer Activity of Chitosan, Chitosan Derivatives, and Their Mechanism of Action
- Review, Var, NA
angioG↓, *Imm↑, *antiOx↑, selectivity↑, other↝, toxicity↓, BioAv↑, eff↝, Half-Life↑, MPT↑, MMP9↓, lipid-P↑, EPR↑, NK cell↑, Casp3↑, Casp8↑, TumCCA↑, ROS↑, DDS↑, VEGF↓, TIMP1↑, ChemoSen↑, eff↑,
5990- Chit,    Chitosan Nanoparticles for Targeted Cancer Therapy: A Review of Stimuli-Responsive, Passive, and Active Targeting Strategies
- Review, Var, NA
DDS↑, eff↓, *Bacteria↓, *antiOx↑, *Wound Healing↑, *Imm↑, TumCP↓, TumMeta↓, angioG↓, Apoptosis↑, ROS↑, ER Stress↑, BioAv↑, Half-Life↑, eff↑, EPR↑, ChemoSen↑, eff↑,
4477- Chit,    Recent Advances in Chitosan and its Derivatives in Cancer Treatment
- Review, NA, NA
*BioAv↑, AntiTum↑, eff↑, TumCG↓, angioG↓, TumMeta↓, eff↑, *toxicity↓, other↝,
4481- Chit,    Antioxidant Properties and Redox-Modulating Activity of Chitosan and Its Derivatives: Biomaterials with Application in Cancer Therapy
- Review, Var, NA
*BioAv↑, *toxicity↓, *antiOx↑, AntiCan↑, *Inflam↓, *ROS↓, *lipid-P↓, MDA↓, selectivity↑, MMP↓, ROS↑, TumCCA↑, MDA↑, GSH↓, ChemoSen↑,
4490- Chit,  FA,    Chitosan Nanoparticle-Based Drug Delivery Systems: Advances, Challenges, and Future Perspectives
- Review, NA, NA
EPR↑, *BioAv↑, *eff↑, *other↝, *Insulin↑, *Bacteria↓, eff↑, ChemoSen↑,
6078- CHL,    Update on the bioavailability and chemopreventative mechanisms of dietary chlorophyll derivatives
- Review, Nor, NA
*BioAv↑, chemoPv↑, *ROS↓, eff↑,
6081- CHL,    Enhancing Health Benefits through Chlorophylls and Chlorophyll-Rich Agro-Food: A Comprehensive Review
- Review, Nor, NA
*antiOx↑, *toxicity↓, *BioAv↓, *BioAv↑, *neuroP↑, *Obesity↓, *AntiCan↑, *TumCP↓, *PhotoS↑, *neuroP↑,
6083- CHOC,    Preventive Effects of Cocoa and Cocoa Antioxidants in Colon Cancer
- Review, Colon, NA
ROS↓, Inflam↓, TumCP↓, Apoptosis↑, *Dose↝, *BioAv↓, *BioAv↑, GSH↑, GSTs↑, PGE2↓, COX1↑, IL8↓, COX2↓, iNOS↓, NF-kB↓, chemoP↑,
6084- CHOC,    Cocoa Polyphenols and Their Potential Benefits for Human Health
- Review, Nor, NA - Review, Stroke, NA - Review, IBD, NA
*lipid-P↓, *ROS↓, *Inflam↓, *BP↓, *cardioP↑, *chemoPv↑, *BioAv⇅, *antiOx↑, *Risk↓, *5LO↓, *AntiAg↑, *Imm↑, *NF-kB↓, *other↓, CYP1A1↓, COX2↓, *Obesity↓, *cognitive↑,
6085- CHOC,    Epicatechin-rich cocoa polyphenol inhibits Kras-activated pancreatic ductal carcinoma cell growth in vitro and in a mouse model
- in-vivo, PC, NA
selectivity↑, TumCP↓, p‑Akt↓, NF-kB↓, TumCG↓, *BioAv↑, *chemoPv↑,
6098- Chol,    Choline
- Review, Nor, NA - Review, AD, NA
*BioAv↝, *Dose↝, *cardioP↑, *BP↓, *cognitive↑, *memory↑, eff∅,
6095- Chol,    Choline metabolism and its implications in cancer
- Review, Var, NA
BioAv↑, other↑, other↑, other↝,
6131- CHr,  Bor,  Z,    Fabrication of phenyl boronic acid modified pH-responsive zinc oxide nanoparticles as targeted delivery of chrysin on human A549 cells
- in-vitro, Lung, A549
*BioAv↑, ROS↑, TumCD↑, TumCCA↑, MMP2↓, TumMeta↓, TumCI↓, GSH↓, eff↑,
6139- CHr,    Chrysin and its nanoformulations in cancer therapy: A systematic review of their radiosensitizing, phototherapy-enhancing potentials
- Review, Var, NA
RadioS↑, PhotoS↑, ROS↑, DNAdam↑, TumCCA↑, TumCD↑, selectivity↑, *ROS↓, *Inflam↓, *DNAdam↓, *antiOx↑, *lipid-P↓, *BioAv↑, eff↑, GSH↓, Catalase↓, ALAT↓, Ca+2↓, MDA↑,
6134- CHr,  QC,  RT,    Comparative Pharmacokinetics and Safety of a Micellar Chrysin–Quercetin–Rutin Formulation: A Randomized Crossover Trial
- Trial, Nor, NA
Dose↝, BioAv↑, MPT↑, eff↑, Half-Life↑,
6135- CHr,    Chrysin as a Multifunctional Therapeutic Flavonoid: Emerging Insights in Pathogenesis Management: A Narrative Review
- Review, Var, NA - Review, AD, NA
Inflam↓, angioG↓, Apoptosis↑, TumAuto↑, TumCCA↑, BioAv↓, Half-Life↓, BioAv↓, *ROS↓, *hepatoP↑, *RenoP↑, TET1↑, MMP9↓, cMyc↓, Ki-67↓, CBR1↓, ROS↑, ChemoSen↑, Bax:Bcl2↑, PUMA↑, NOTCH1↑, *AntiDiabetic↑, *neuroP↑, *GABA↑, *DNAdam↓, *BDNF↑, *memory↑, *AGEs↓, *Aβ↓, *cardioP↑, *AntiArt↑, eff↑, eff↑, *eff↑, RadioS↑, eff↑, ChemoSen↑, eff↑,
6128- CHr,    Chrysin: A Comprehensive Review of Its Pharmacological Properties and Therapeutic Potential
- Review, Nor, NA - Review, Var, NA - Review, AD, NA
*antiOx↑, *Inflam↓, AntiCan↑, *neuroP↑, *ROS↓, *BioAv↓, *BioAv↑, *cardioP↑, *COX2↓, *TNF-α↓, *IL1β↓, *NF-kB↓, *lipid-P↓, *Apoptosis↓, *NRF2↑, *HO-1↑, *MDA↓, *GSH↑, *SOD↑, *GPx↑, *GSR↑, *Catalase↑, *5HT↑, *Casp3↓, *Casp9↓, TumCCA↑, MAPK↓, PI3K↓, Akt↓, TumCP↓, TET1↑, TLR4↓, HER2/EBBR2↓, HK2↓, Glycolysis↓, glucose↓, lactateProd↓, ROS↑, mTOR↓, TumAuto↑, tumCV↓, ER Stress↑, UPR↑, PERK↑, ATF4↑, eIF2α↑, BioAv↑,
6123- CHr,    Developing nutritional component chrysin as a therapeutic agent: Bioavailability and pharmacokinetics consideration, and ADME mechanisms
- Review, Nor, NA
*eff↓, *BioAv↓, *eff↑, *BioAv↓, OATPs↓, MRP↓,
6122- CHr,    Disposition and metabolism of the flavonoid chrysin in normal volunteers
- Human, Nor, NA
*Dose↝, *BioAv↓,
2780- CHr,    Anti-cancer Activity of Chrysin in Cancer Therapy: a Systematic Review
- Review, Var, NA
*antiOx↑, Inflam↓, *hepatoP↑, AntiCan↑, Cyt‑c↑, Casp3↑, XIAP↓, p‑Akt↓, PI3K↑, Apoptosis↑, COX2↓, FAK↓, AMPK↑, STAT3↑, MMP↓, DNAdam↑, BAX↑, Bak↑, Casp9↑, p38↑, MAPK↑, TumCCA↑, ChemoSen↑, HDAC8↓, Wnt↓, NF-kB↓, angioG↓, BioAv↓,
2781- CHr,  PBG,    Chrysin a promising anticancer agent: recent perspectives
- Review, Var, NA
PI3K↓, Akt↓, mTOR↓, MMP9↑, uPA↓, VEGF↓, AR↓, Casp↑, TumMeta↓, TumCCA↑, angioG↓, BioAv↓, *hepatoP↑, *neuroP↑, *SOD↑, *GPx↑, *ROS↓, *Inflam↓, *Catalase↑, *MDA↓, ROS↓, BBB↑, Half-Life↓, BioAv↑, ROS↑, eff↑, ROS↑, ROS↑, lipid-P↑, ER Stress↑, NOTCH1↑, NRF2↓, p‑FAK↓, Rho↓, PCNA↓, COX2↓, NF-kB↓, PDK1↓, PDK3↑, GLUT1↓, Glycolysis↓, mt-ATP↓, Ki-67↓, cMyc↓, ROCK1↓, TOP1↓, TNF-α↓, IL1β↓, CycB/CCNB1↓, CDK2↓, EMT↓, STAT3↓, PD-L1↓, IL2↑,
2782- CHr,    Broad-Spectrum Preclinical Antitumor Activity of Chrysin: Current Trends and Future Perspectives
- Review, Var, NA - Review, Stroke, NA - Review, Park, NA
*antiOx↑, *Inflam↓, *hepatoP↑, *neuroP↑, *BioAv↓, *cardioP↑, *lipidLev↓, *RenoP↑, *TNF-α↓, *IL2↓, *PI3K↓, *Akt↓, *ROS↓, *cognitive↑, eff↑, cycD1/CCND1↓, hTERT/TERT↓, VEGF↓, p‑STAT3↓, TumMeta↓, TumCP↓, eff↑, eff↑, IL1β↓, IL6↓, NF-kB↓, ROS↑, MMP↓, Cyt‑c↑, Apoptosis↑, ER Stress↑, Ca+2↑, TET1↑, Let-7↑, Twist↓, EMT↓, TumCCA↑, Casp3↑, Casp9↑, BAX↑, HK2↓, GlucoseCon↓, lactateProd↓, Glycolysis↓, SHP1↑, N-cadherin↓, E-cadherin↑, UPR↑, PERK↑, ATF4↑, eIF2α↑, RadioS↑, NOTCH1↑, NRF2↓, BioAv↑, eff↑,
2784- CHr,    Chrysin targets aberrant molecular signatures and pathways in carcinogenesis (Review)
- Review, Var, NA
Apoptosis↑, TumCMig↓, *toxicity↝, ChemoSen↑, *BioAv↓, Dose↝, neuroP↑, *P450↓, *ROS↓, *HDL↑, *GSTs↑, *SOD↑, *Catalase↑, *MAPK↓, *NF-kB↓, *PTEN↑, *VEGF↑, ROS↑, MMP↓, Ca+2↑, selectivity↑, PCNA↓, Twist↓, EMT↓, CDKN1C/p57↑, p‑STAT3↑, MMP2↓, MMP9↓, eff↑, cycD1/CCND1↓, hTERT/TERT↓, CLDN1↓, TumVol↓, OS↑, COX2↓, eff↑, CDK2↓, CDK4↓, selectivity↑, TumCCA↑, E-cadherin↑, HK2↓, HDAC↓,
2785- CHr,    Emerging cellular and molecular mechanisms underlying anticancer indications of chrysin
- Review, Var, NA
*NF-kB↓, *COX2↓, *iNOS↓, angioG↓, TOP1↓, HDAC↓, TNF-α↓, IL1β↓, cardioP↑, RenoP↑, neuroP↑, LDL↓, BioAv↑, eff↑, cycD1/CCND1↓, hTERT/TERT↓, MMP-10↓, Akt↓, STAT3↓, VEGF↓, EGFR↓, Snail↓, Slug↓, Vim↓, E-cadherin↑, eff↑, TET1↑, ROS↑, mTOR↓, PPARα↓, ER Stress↑, Ca+2↑, ERK↓, MMP↑, Cyt‑c↑, Casp3↑, HK2↓, NRF2↓, HO-1↓, MMP2↓, MMP9↓, Fibronectin↓, GRP78/BiP↑, XBP-1↓, p‑eIF2α↑, *AST↓, ALAT↓, ALP↓, LDH↓, COX2↑, Bcl-xL↓, IL6↓, PGE2↓, iNOS↓, DNAdam↑, UPR↑, Hif1a↓, EMT↓, Twist↓, lipid-P↑, CLDN1↓, PDK1↓, IL10↓, TLR4↓, NOTCH1↑, PARP↑, Mcl-1↓, XIAP↓,
2787- CHr,    Network pharmacology unveils the intricate molecular landscape of Chrysin in breast cancer therapeutics
- Analysis, Var, MCF7
TumCP↓, angioG↓, TumCI↓, TumMeta↓, TP53↑, Akt↓, Casp3↑, tumCV↓, TNF-α↓, BioAv↑, BioAv↑, AKT1↓,
2788- CHr,    Chrysin: Sources, beneficial pharmacological activities, and molecular mechanism of action
- Review, Var, NA
*neuroP↑, *Inflam↓, *ROS↓, NF-kB↓, *PCNA↓, *COX2↓, ChemoSen↑, Hif1a↓, angioG↓, *chemoPv↑, PDGF↓, *memory↑, *RenoP↑, *PPARα↑, *lipidLev↓, *hepatoP↑, *cardioP⇅, *BioAv↓,

Showing Research Papers: 201 to 250 of 635
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* indicates research on normal cells as opposed to diseased cells
Total Research Paper Matches: 635

Pathway results for Effect on Cancer / Diseased Cells:


NA, unassigned(tgid=0) ⓘ

CBR1↓, 1,  

Redox & Oxidative Stress(tgid=1) ⓘ

antiOx↑, 2,   Catalase↓, 1,   CYP1A1↓, 1,   Ferroptosis↑, 1,   GSH↓, 3,   GSH↑, 2,   GSTs↑, 1,   HO-1↓, 1,   HO-1↑, 1,   lipid-P↑, 3,   MDA↓, 1,   MDA↑, 2,   NRF2↓, 3,   NRF2↑, 1,   ROS↓, 3,   ROS↑, 15,  

Mitochondria & Bioenergetics(tgid=3) ⓘ

ATP↓, 1,   mt-ATP↓, 1,   MMP↓, 5,   MMP↑, 1,   MPT↑, 2,   XIAP↓, 2,  

Core Metabolism/Glycolysis(tgid=4) ⓘ

AKT1↓, 1,   ALAT↓, 2,   AMPK↑, 2,   cMyc↓, 2,   glucose↓, 1,   GlucoseCon↓, 1,   Glycolysis↓, 4,   HK2↓, 4,   lactateProd↓, 2,   LDH↓, 1,   LDL↓, 1,   PDK1↓, 2,   PDK3↑, 1,   PPARα↓, 1,   TCA↓, 1,  

Cell Death(tgid=5) ⓘ

Akt↓, 5,   p‑Akt↓, 3,   Apoptosis↑, 11,   Bak↑, 1,   BAX↑, 3,   Bax:Bcl2↑, 1,   Bcl-2↓, 1,   Bcl-xL↓, 1,   Casp↑, 1,   Casp3↑, 6,   Casp8↑, 1,   Casp9↑, 2,   Cyt‑c↑, 3,   Ferroptosis↑, 1,   hTERT/TERT↓, 3,   iNOS↓, 2,   JNK↑, 1,   MAPK↓, 2,   MAPK↑, 2,   MAPK↝, 1,   Mcl-1↓, 1,   p38↑, 1,   PUMA↑, 1,   TumCD↑, 3,  

Kinase & Signal Transduction(tgid=6) ⓘ

HER2/EBBR2↓, 1,  

Transcription & Epigenetics(tgid=7) ⓘ

other↑, 3,   other↝, 6,   PhotoS↑, 1,   tumCV↓, 2,  

Protein Folding & ER Stress(tgid=8) ⓘ

eIF2α↑, 2,   p‑eIF2α↑, 1,   ER Stress↑, 5,   GRP78/BiP↑, 1,   PERK↑, 2,   UPR↑, 3,   XBP-1↓, 1,  

Autophagy & Lysosomes(tgid=9) ⓘ

TumAuto↑, 2,  

DNA Damage & Repair(tgid=10) ⓘ

DNAdam↑, 4,   P53↑, 2,   PARP↑, 1,   PCNA↓, 2,   TP53↑, 1,  

Cell Cycle & Senescence(tgid=11) ⓘ

CDK1↑, 1,   CDK2↓, 2,   CDK4↓, 1,   CycB/CCNB1↓, 1,   cycD1/CCND1↓, 3,   P21↑, 2,   TumCCA↑, 12,  

Proliferation, Differentiation & Cell State(tgid=12) ⓘ

CD44↓, 1,   CSCs↓, 1,   EMT↓, 4,   ERK↓, 2,   HDAC↓, 2,   HDAC8↓, 1,   Let-7↑, 1,   mTOR↓, 6,   Nanog↓, 1,   NOTCH↓, 1,   NOTCH1↑, 4,   OCT4↓, 1,   PI3K↓, 4,   PI3K↑, 1,   PI3K↝, 1,   SHP1↑, 1,   SOX2↓, 1,   STAT3↓, 2,   STAT3↑, 1,   p‑STAT3↓, 1,   p‑STAT3↑, 1,   TOP1↓, 3,   TOP2↓, 1,   TumCG↓, 2,   Wnt↓, 1,   Wnt↝, 1,  

Migration(tgid=13) ⓘ

Ca+2↓, 1,   Ca+2↑, 4,   CDKN1C/p57↑, 1,   CLDN1↓, 2,   E-cadherin↑, 3,   FAK↓, 1,   p‑FAK↓, 1,   Fibronectin↓, 1,   Ki-67↓, 3,   MMP-10↓, 1,   MMP2↓, 3,   MMP9↓, 4,   MMP9↑, 1,   N-cadherin↓, 1,   PDGF↓, 1,   Rho↓, 1,   ROCK1↓, 1,   Slug↓, 1,   Snail↓, 1,   TET1↑, 4,   TIMP1↑, 1,   TJ↓, 1,   TumCI↓, 4,   TumCMig↓, 2,   TumCP↓, 9,   TumMeta↓, 9,   Twist↓, 3,   uPA↓, 1,   Vim↓, 1,  

Angiogenesis & Vasculature(tgid=14) ⓘ

angioG↓, 12,   ATF4↑, 2,   EGFR↓, 2,   EPR↑, 5,   Hif1a↓, 4,   VEGF↓, 6,  

Barriers & Transport(tgid=15) ⓘ

BBB↑, 1,   GLUT1↓, 1,   MRP↓, 1,   OATPs↓, 1,  

Immune & Inflammatory Signaling(tgid=16) ⓘ

COX1↑, 1,   COX2↓, 6,   COX2↑, 1,   IFN-γ↑, 1,   IL10↓, 1,   IL10↑, 1,   IL1β↓, 4,   IL2↑, 2,   IL6↓, 3,   IL8↓, 1,   Inflam↓, 3,   NF-kB↓, 6,   NK cell↑, 2,   PD-L1↓, 1,   PGE2↓, 2,   TLR4↓, 2,   TNF-α↓, 4,  

Hormonal & Nuclear Receptors(tgid=20) ⓘ

AR↓, 1,  

Drug Metabolism & Resistance(tgid=21) ⓘ

BioAv↓, 6,   BioAv↑, 16,   BioAv↝, 2,   BioEnh↑, 1,   ChemoSen↑, 11,   DDS↑, 9,   Dose↝, 2,   eff↓, 1,   eff↑, 36,   eff↝, 1,   eff∅, 1,   Half-Life↓, 3,   Half-Life↑, 5,   RadioS↑, 3,   selectivity↑, 7,  

Clinical Biomarkers(tgid=22) ⓘ

ALAT↓, 2,   ALP↓, 1,   AR↓, 1,   EGFR↓, 2,   HER2/EBBR2↓, 1,   hTERT/TERT↓, 3,   IL6↓, 3,   Ki-67↓, 3,   LDH↓, 1,   PD-L1↓, 1,   TP53↑, 1,  

Functional Outcomes(tgid=23) ⓘ

AntiCan↑, 3,   AntiTum↑, 3,   cardioP↑, 1,   chemoP↑, 1,   chemoPv↑, 1,   neuroP↑, 2,   OS↑, 1,   RenoP↑, 1,   toxicity↓, 5,   TumVol↓, 1,   Wound Healing↑, 2,  

Infection & Microbiome(tgid=24) ⓘ

Bacteria↓, 1,  
Total Targets: 208

Pathway results for Effect on Normal Cells:


NA, unassigned(tgid=0) ⓘ

AntiArt↑, 1,  

Redox & Oxidative Stress(tgid=1) ⓘ

antiOx↓, 1,   antiOx↑, 12,   Catalase↑, 5,   Ferroptosis↓, 1,   GPx↑, 3,   GSH↑, 2,   GSR↑, 1,   GSTs↑, 1,   H2O2↓, 1,   HDL↑, 2,   HO-1↓, 1,   HO-1↑, 2,   Keap1↓, 1,   lipid-P↓, 4,   MDA↓, 3,   NRF2↑, 4,   ROS↓, 16,   SOD↑, 5,   SOD1↑, 1,  

Mitochondria & Bioenergetics(tgid=3) ⓘ

Insulin↑, 1,  

Core Metabolism/Glycolysis(tgid=4) ⓘ

glucose↝, 2,   GLUT2↑, 1,   HMG-CoA↓, 1,   lipidLev↓, 2,   NADPH↓, 1,   PPARα↑, 1,  

Cell Death(tgid=5) ⓘ

Akt↓, 1,   Apoptosis↓, 1,   Casp3↓, 2,   Casp9↓, 2,   Fas↓, 1,   Ferroptosis↓, 1,   HGF/c-Met↑, 1,   iNOS↓, 2,   JNK↓, 1,   MAPK↓, 2,   MCT1↓, 1,  

Transcription & Epigenetics(tgid=7) ⓘ

other↓, 1,   other↝, 4,   PhotoS↑, 1,  

Protein Folding & ER Stress(tgid=8) ⓘ

CHOP↑, 1,   GRP78/BiP↑, 1,   GRP94↑, 1,  

DNA Damage & Repair(tgid=10) ⓘ

DNAdam↓, 2,   DNMT1↓, 1,   PCNA↓, 1,  

Proliferation, Differentiation & Cell State(tgid=12) ⓘ

p‑ERK↑, 1,   PI3K↓, 1,   PTEN↑, 1,  

Migration(tgid=13) ⓘ

5LO↓, 1,   AntiAg↑, 3,   TumCP↓, 1,  

Angiogenesis & Vasculature(tgid=14) ⓘ

TXA2↓, 1,   VEGF↓, 1,   VEGF↑, 1,  

Barriers & Transport(tgid=15) ⓘ

BBB↑, 1,   GastroP↑, 1,   IBI↑, 1,   OCLN↓, 1,  

Immune & Inflammatory Signaling(tgid=16) ⓘ

COX2↓, 4,   IL1β↓, 2,   IL2↓, 1,   Imm↑, 5,   Inflam↓, 11,   NF-kB↓, 8,   TLR4↓, 2,   TNF-α↓, 3,   TNF-α↑, 1,  

Synaptic & Neurotransmission(tgid=18) ⓘ

5HT↑, 1,   BDNF↑, 1,   GABA↑, 1,  

Protein Aggregation(tgid=19) ⓘ

AGEs↓, 2,   Aβ↓, 4,   NLRP3↓, 1,  

Drug Metabolism & Resistance(tgid=21) ⓘ

BioAv↓, 12,   BioAv↑, 25,   BioAv⇅, 1,   BioAv↝, 9,   Dose↝, 7,   eff↓, 1,   eff↑, 5,   Half-Life↓, 1,   Half-Life↝, 1,   P450↓, 1,  

Clinical Biomarkers(tgid=22) ⓘ

AST↓, 1,   BP↓, 3,   GutMicro↑, 3,  

Functional Outcomes(tgid=23) ⓘ

AntiCan↑, 1,   AntiDiabetic↑, 3,   cardioP↑, 9,   cardioP⇅, 1,   chemoPv↑, 3,   cognitive↑, 3,   hepatoP↑, 8,   memory↑, 3,   neuroP↑, 11,   Obesity↓, 5,   RenoP↑, 5,   Risk↓, 1,   toxicity↓, 7,   toxicity↝, 1,   Weight↝, 1,   Wound Healing↑, 2,  

Infection & Microbiome(tgid=24) ⓘ

Bacteria↓, 6,  
Total Targets: 105

Scientific Paper Hit Count for: BioAv, bioavailability
49 Curcumin
21 EGCG (Epigallocatechin Gallate)
20 chitosan
18 Baicalein
17 Quercetin
17 Chlorogenic acid
16 Selenium NanoParticles
16 Resveratrol
16 Sulforaphane (mainly Broccoli)
15 Apigenin (mainly Parsley)
15 Berberine
15 Chrysin
14 Pterostilbene
13 Thymoquinone
11 Silymarin (Milk Thistle) silibinin
11 Lycopene
10 Alpha-Lipoic-Acid
10 Carvacrol
9 Astaxanthin
9 borneol
9 Honokiol
9 Rosmarinic acid
8 Capsaicin
8 Crocetin
8 Piperlongumine
8 Urolithin
7 Allicin (mainly Garlic)
7 Artemisinin
7 Betulinic acid
7 Luteolin
7 Phenethyl isothiocyanate
6 Silver-NanoParticles
6 Ashwagandha(Withaferin A)
6 Biochanin A
6 Thymol-Thymus vulgaris
6 Propolis -bee glue
6 Ellagic acid
6 Emodin
6 Eugenol
5 beta-glucans
5 Baicalin
5 Boswellia (frankincense)
5 Centella asiatica / Gotu kola → asiaticoside
5 Cucurbitacin
5 Piperine
5 Fisetin
5 Magnolol
5 Naringin
5 Selenite (Sodium)
4 1,8-Cineole
4 5-Hydroxytryptophan
4 Beta-Caryophyllene
4 Boron
4 Celastrol
4 Phenylbutyrate
4 Vitamin C (Ascorbic Acid)
4 Shikonin
4 Aflavin-3,3′-digallate
3 Ascorbyl Palmitate
3 Gold NanoParticles
3 Berbamine
3 Caffeic acid
3 Folic Acid, Vit B9
3 Chocolate
3 Rutin
3 Cinnamon
3 Hydroxycinnamic-acid
3 Coenzyme Q10
3 Copper and Cu NanoParticles
3 Diclofenac
3 Disulfiram
3 Ferulic acid
3 HydroxyTyrosol
3 Lecithin
3 Magnetic Fields
3 Niclosamide (Niclocide)
3 Selenium
3 Silicic Acid
3 Spermidine
3 Terpinen-4-ol / Tea Tree Oil
2 3-bromopyruvate
2 Auranofin
2 Astragalus
2 Citric Acid
2 Chemotherapy
2 Aspirin
2 Paclitaxel
2 Atorvastatin
2 immunotherapy
2 Radiotherapy/Radiation
2 Butyrate
2 Melatonin
2 Cynanbungeigenin C (CBC) and D (CBD)
2 Chlorophyllin
2 Choline
2 Camptothecin
2 Dasatinib/Phyrago
2 Dichloroacetate
2 Deguelin
2 D-limonene
2 Shilajit/Fulvic Acid
2 Gallic acid
2 Geraniol
2 Methyl salicylate / Sweet Birch oil
2 magnetic nanoparticles
2 nicotinamide adenine dinucleotide
2 Oleuropein
2 Turmerones
2 Ursolic acid
1 Aluminum
1 Anethole/trans-Anethole
1 Aromatherapy
1 Gemcitabine (Gemzar)
1 Aloe anthraquinones
1 doxorubicin
1 Docetaxel
1 xanthohumol
1 beta-carotene(VitA)
1 Bicalutamide
1 Bacopa monnieri
1 α-Bisabolol / Chamomile oil
1 Carnosic acid
1 urea
1 capecitabine
1 Catechins
1 Cat’s Claw
1 Cannabidiol
1 Zinc
1 irinotecan
1 Cyclopamine
1 Dichloroacetophenone(2,2-)
1 Dandelion Root
1 Echinacea
1 Electrical Pulses
1 Eurycomanone
1 Fenbendazole
1 flavonoids
1 Kaempferol
1 MCToil
1 Gambogic Acid
1 Genistein (soy isoflavone)
1 Germacranolide
1 Hydrogen Gas
1 HydroxyCitric Acid
1 itraconazole
1 Methylene blue
1 Metformin
1 Magnesium
1 Bicarbonate(Sodium)
1 Oleocanthal
1 Oxygen, Hyperbaric
1 Cisplatin
1 Psoralidin
1 Parthenolide
1 enzalutamide
1 salinomycin
1 Date Fruit Extract
1 cetuximab
1 Tomatine
1 Vitamin B3,Niacin
1 Vitamin D3
1 Vitamin E
1 Vitamin K2
Query results interpretion may depend on "conditions" listed in the research papers.
Such Conditions may include : 
  -low or high Dose
  -format for product, such as nano of lipid formations
  -different cell line effects
  -synergies with other products 
  -if effect was for normal or cancerous cells

Filter Conditions: Pro/AntiFlg:%  IllCat:%  CanType:%  Cells:%  prod#:%  Target#:792  State#:%  Dir#:%
  wNotes=0  sortOrder:rid,rpid

 

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