Inflam Cancer Research Results

Inflam, inflammation: Click to Expand ⟱
Source:
Type:
Cancer and inflammation are closely linked, with chronic inflammation contributing to the development and progression of cancer. Various inflammatory mediators and cells are involved in this process.
Scientific Papers found: Click to Expand⟱
5755- CA,    Caffeic Acid as a Promising Natural Feed Additive: Advancing Sustainable Aquaculture
- Review, Nor, NA
*Imm↑, *Inflam↓, *Bacteria↓, *eff↑, *ROS↓, *MDA↓, *Catalase↑, *GSH↑, *TAC↑, *NF-kB↓, *NLRP3↓, *eff↑, *AST↓, *ALAT↓, *SOD↑, *GSTA1↑,
5751- CA,    Potential Therapeutic Implications of Caffeic Acid in Cancer Signaling: Past, Present, and Future
- Review, Var, NA
*antiOx↑, *chemoPv↑, ROS↑, MMP2↓, MMP9↓, BioAv↓, eff↑, *Inflam↓, AMPK↑, lipid-P↑, eff↑, ChemoSen↑, *memory↑, *ROS↓,
5872- CA,    Nrf2/ARE-Mediated Antioxidant Actions of Pro-Electrophilic Drugs
- Review, Nor, NA
*NRF2↑, *GSH↑, *neuroP↑, *Inflam↓, *cardioP↑, *Obesity↓, *angioG↓, chemoP↑, *NF-kB↓,
5834- CAP,    Capsaicin and TRPV1: A Novel Therapeutic Approach to Mitigate Vascular Aging
- Study, Nor, NA
*AntiCan↑, *Inflam↓, *antiOx↑, *TRPV1↑, *AMPK↑, *SIRT1↑, *NADPH↓, *ROS↓, *MAPK↓, *eNOS↑, *Wnt/(β-catenin)↓, RenoP↑,
5832- CAP,    Capsaicin induces cell cycle arrest and apoptosis in human KB cancer cells
- in-vitro, Oral, KB
TumCP↓, tumCV↓, TumCCA↑, Apoptosis↑, MMP↓, Casp9↑, Casp3↑, PARP↑, Inflam↓, Pain↓,
5830- CAP,    Inhibition of pyroptosis and apoptosis by capsaicin protects against LPS-induced acute kidney injury through TRPV1/UCP2 axis in vitro
- in-vitro, Nor, HK-2
*IL1β↓, *IL18↓, *TRPV1↑, *ROS↓, *MMP↑, *Apoptosis↓, *RenoP↑, *Inflam↓, *UCPs↑,
5825- CAP,    Bioavailability of capsaicin and its implications for drug delivery
- Review, Var, NA - Review, Arthritis, NA - Review, Obesity, NA
*AntiCan↑, *TRPV1↑, *cardioP↑, AntiCan↓, Apoptosis↑, ChemoSen↑, *Inflam↓, *Pain↓, *AntiAg↑, *Weight↓, *BioAv↑, BioAv↑, Half-Life↝, Half-Life↓,
5861- CAP,    Anticancer Properties of Capsaicin Against Human Cancer
- Review, Var, NA
*antiOx↑, *Inflam↓, *Obesity↓, chemoPv↑, Apoptosis↑, selectivity↑, TRPV1↑, Ca+2↑, mtDam↑, Cyt‑c↑, P53↑, SIRT1↓, TumCCA↑, P21↑, CDK4↓, CDK6↓, cycE/CCNE↓, angioG↓, TumMeta↓,
5859- CAP,    Are We Ready to Recommend Capsaicin for Disorders Other Than Neuropathic Pain?
- Review, Var, NA
*TRPV1↑, *Ca+2↑, *Na+↑, *UCPs↑, *SIRT1↑, *PPARγ↑, *Inflam↓, *lipid-P↑, *IL6↓, *TNF-α↓, *NF-kB↓, *p‑Akt↑, *NRF2↑, *HO-1↑, *ROS↑, *GutMicro↑,
5858- CAP,    Capsaicin as a Microbiome Modulator: Metabolic Interactions and Implications for Host Health
- Review, Nor, NA - Review, AD, NA
*BBB↓, *GutMicro↑, Obesity↓, *Inflam↓, *AntiCan↑, *TRPV1↑, *Ca+2↑, *antiOx↑, *cardioP↑, *BioAv↓, *Half-Life↓, *BioAv↝, *BioAv↑, *neuroP↑, Apoptosis↑, p38↑, ROS↑, MMP↓, MPT↑, Cyt‑c↑, Casp↑, TRIB3↑, NADH↓, SIRT1↓, TumCG↓, TumCMig↓, TOP1↓, TOP2↓, β-catenin/ZEB1↓, *ROS↓, *Aβ↓,
5854- CAP,    Pharmacological activity of capsaicin: Mechanisms and controversies (Review)
- Review, Var, NA - Review, AD, NA
Obesity↓, Half-Life↓, antiOx↑, TRPV1↑, STAT3↓, Ca+2↑, ROS↑, MMP↓, *neuroP↑, *tau↓, *Inflam↓, *ROS?,
5202- CAP,    Capsaicin Suppresses Cell Proliferation, Induces Cell Cycle Arrest and ROS Production in Bladder Cancer Cells through FOXO3a-Mediated Pathways
- vitro+vivo, Bladder, 5637 - in-vitro, Bladder, T24/HTB-9
antiOx↑, Inflam↓, AntiCan↓, TRPV1↑, TumCP↓, TumCCA↑, ROS↑, FOXO3↑, TumCMig↓,
3854- CAP,    Capsaicin consumption reduces brain amyloid-beta generation and attenuates Alzheimer’s disease-type pathology and cognitive deficits in APP/PS1 mice
- in-vivo, AD, NA
*Aβ↓, *cognitive↑, *APP↓, *MMP-10↝, *p‑tau↓, *Inflam↓, *neuroP↑, *Risk↓, *TNF-α↓, *IFN-γ↓, *IL6↓, *PPARα↑,
3855- CAP,    Capsaicin consumption reduces brain amyloid-beta generation and attenuates Alzheimer’s disease-type pathology and cognitive deficits in APP/PS1 mice
- in-vivo, AD, NA
*Risk↓, *Aβ↓, *p‑tau↓, *Inflam↓, *neuroP↑, *cognitive↑, *ADAM10↑, *PPARα↑,
2394- CAP,    Capsaicin acts as a novel NRF2 agonist to suppress ethanol induced gastric mucosa oxidative damage by directly disrupting the KEAP1-NRF2 interaction
- in-vitro, Nor, GES-1
*mtDam↓, *NRF2↑, *HO-1↑, *Trx↑, *GSS↑, *NQO1↑, *Keap1↓, *ROS↓, *PKM2↓, *LDHA↓, *Inflam↓,
2347- CAP,    Capsaicin ameliorates inflammation in a TRPV1-independent mechanism by inhibiting PKM2-LDHA-mediated Warburg effect in sepsis
- in-vivo, Nor, NA - in-vitro, Nor, RAW264.7
*PKM2↓, *LDHA↓, *Warburg↓, *COX2↓, *Sepsis↓, *Inflam↓, *ECAR↓, *OCR↑,
2348- CAP,    Recent advances in analysis of capsaicin and its effects on metabolic pathways by mass spectrometry
- Analysis, Nor, NA
Warburg↓, *PKM2↓, *COX2↓, *Inflam↓, *Sepsis↓, *AMPK↑, *PKA↑, *mitResp↑, *FAO↑, *FASN↓, *PGM1?, *ATP↑, *ROS↓,
2019- CAP,    Capsaicin: A Two-Decade Systematic Review of Global Research Output and Recent Advances Against Human Cancer
- Review, Var, NA
chemoPv↑, Ca+2↑, antiOx↑, *ROS↓, *MMP∅, *Cyt‑c∅, *Casp3∅, *eff↑, *Inflam↓, *NF-kB↓, *COX2↓, iNOS↓, TRPV1↑, i-Ca+2?, MMP↓, Cyt‑c↑, Bax:Bcl2↑, P53↑, JNK↑, PI3K↓, Akt↓, mTOR↓, LC3II↑, ATG5↑, p62↑, Fap1↓, Casp3↑, Apoptosis↑, ROS↑, MMP9↓, eff↑, eff↓, eff↑, selectivity↑, eff↑, ChemoSen↑,
5768- CAPE,    Neuroprotective Potential of Caffeic Acid Phenethyl Ester (CAPE) in CNS Disorders: Mechanistic and Therapeutic Insights
- Review, AD, NA - Review, Park, NA - Review, Stroke, NA
*antiOx↑, *Inflam↑, *AntiCan↑, *NRF2↑, *GSK‐3β↑, *Akt↑, *PI3K↑, *ROS↓, *SOD↑, *GSH↑, *MDA↓, *tau↓, *neuroP↑, *memory↑, *AChE↓, *other↝, *lipid-P↓,
5770- CAPE,    Caffeic acid phenethyl ester is a potent and specific inhibitor of activation of nuclear transcription factor NF-kappa B
- in-vitro, Nor, NA
*NF-kB↓, *Imm↑, *Inflam↓,
5766- CAPE,    A Nano-Liposomal Formulation of Caffeic Acid Phenethyl Ester Modulates Nrf2 and NF-κβ Signaling and Alleviates Experimentally Induced Acute Pancreatitis in a Rat Model
- in-vivo, Nor, NA
*MDA↓, *NF-kB↓, *p65↓, *TNF-α↓, *cl‑Casp3↓, *GSR↑, *GSH↑, *NRF2↑, *HO-1↑, *Bax:Bcl2↓, *antiOx↑, *Inflam↓,
5758- CAPE,  PBG,    Caffeic acid phenethyl ester and therapeutic potentials
- Review, Var, NA
*antiOx↑, *Inflam↓, ChemoSen↑, chemoP↑, COX1↓, COX2↓, selectivity↑, NF-kB↓, RadioS↑, *ROS↓, *lipid-P↓,
5887- CAR,  TV,    Antitumor Effects of Carvacrol and Thymol: A Systematic Review
- Review, Var, NA
Apoptosis↑, TumCCA↑, TumMeta↓, TumCP↓, MAPK↓, PI3K↓, Akt↓, mTOR↓, eff↑, *Inflam↓, *antiOx↑, AXL↓, MDA↑, Casp3↑, Bcl-2↓, MMP2↓, MMP9↓, p‑JNK↑, BAX↑, MDA↓, TRPM7↓, MMP↓, Cyt‑c↑, Casp↑, cl‑PARP↑, ROS↑, CDK4↓, P21↑, F-actin↓, GSH↓, *SOD↑, *Catalase↑, *GPx↑, *GSR↑, *GSH↑, *lipid-P↓, *AST↓, *ALAT↓, *ALP↓, *LDH↓, DNAdam↑, AFP↓, VEGF↓, Weight↑, *chemoP↑, ROS↑,
5885- CAR,    Inhibition of TRPM7 by carvacrol suppresses glioblastoma cell proliferation, migration and invasion
- in-vitro, GBM, U87MG - in-vitro, Nor, HEK293
TRPM7↓, tumCV↓, TumCMig↓, TumCI↓, MMP2↓, toxicity↓, *Inflam↓, AntiDiabetic↑, cardioP↑, neuroP↑, selectivity↑, Apoptosis↑, p‑Cofilin↑, F-actin↓, PI3K↓, Akt↓, MEK↓, MAPK↓,
5881- CAR,    Carvacrol—A Natural Phenolic Compound with Antimicrobial Properties
- Review, Nor, NA
*Bacteria↓, *Inflam↓, *SOD↑, *GPx↑, *GSR↑, *Catalase↑, *toxicity↓, *Pain↓, *other↑, *cardioP↑, *RenoP↑, *neuroP↑, *antiOx↑, *AntiDiabetic↑, *hepatoP↑, *Obesity↓, *AntiAg↑, *BioAv↓, BioAv↝, *OS↑, MMP↓, ROS↑, *MDA↓, *lipid-P↓, *COX2↓, *Dose↝,
5907- CAR,    Anti-proliferative and pro-apoptotic effect of carvacrol on human hepatocellular carcinoma cell line HepG-2
- in-vitro, Liver, HepG2
TumCG↓, Apoptosis↓, Casp3↓, cl‑PARP↑, Bcl-2↓, p‑ERK↓, p‑p38↑, *Bacteria↓, *AntiAg↑, *Inflam↓, *antiOx↑, *AChE↓, AntiTum↑, MMP↓, Cyt‑c↑, Bax:Bcl2↑, Casp↑, DNAdam↑, selectivity↑,
5896- CAR,  TV,    Carvacrol and Thymol Hybrids: Potential Anticancer and Antibacterial Therapeutics
- Review, Var, NA
BioAv↑, AntiCan↑, *antiOx↑, *Inflam↑, *Bacteria↓, ROS↑, DNAdam↑,
5900- CAR,  TV,    Lights and Shadows of Essential Oil-Derived Compounds: Antimicrobial and Anti-Inflammatory Properties of Eugenol, Thymol, Cinnamaldehyde, and Carvacrol
- Review, Nor, NA
*Bacteria↓, *Inflam↓, *cardioP↑, *neuroP↑, *NADPH↓, *NRF2↑, *HO-1↑, *IL1β↓, *TNF-α↓,
5898- CAR,    Carvacrol-induced apoptosis via tumor suppressor gene activation and oxidative stress modulation in a rat model of breast cancer
- in-vivo, BC, NA
*lipid-P↓, *MDA↓, *antiOx↑, *Inflam↑, RenoP↑, hepatoP↑, *ALAT↓, AST↓, creat↓, chemoPv↑, Cyt‑c↑, FADD↑, P53↑,
5894- CAR,    Targeting Gastrointestinal Cancers with Carvacrol: Mechanistic Insights and Therapeutic Potential
- Review, Var, NA
AntiCan↑, Apoptosis↑, Inflam↓, angioG↓, TumMeta↓, selectivity↑, BioAv↑, ChemoSen↑, Dose↝, TumCP↓, hepatoP↑, Casp3↑, Casp9↑, Bcl-2↓, ROS↑, GSH↓, BAX↑, Casp7↑, Casp8↑, Cyt‑c↑, Fas↑, FADD↑, P53↑, Bcl-2↓, TumMeta↓, TumCMig↓, TumCI↓, E-cadherin↑, TIMP2↑, TIMP3↑, N-cadherin↓, ZEB2↓, *lipid-P↓, *AST↓, *ALAT↓, *ALP↓, *LDH↓, *SOD↑, *Catalase↑, *GPx↑, *GSR↑, selectivity↑, cl‑PARP↑, ERK↓, p38↑, OS↑, AFP↓, COX2↓, VEGF↓, PCNA↓, Ki-67↓, TNF-α↓, BioAv↓,
5893- CAR,  TV,    Thymol and Carvacrol: Molecular Mechanisms, Therapeutic Potential, and Synergy With Conventional Therapies in Cancer Management
- Review, Var, NA
*Inflam↓, AntiCan↑, PI3K↓, Akt↓, mTOR↓, NOTCH↓, PIK3CA↓, EGFR↓, Hif1a↓, VEGF↓, ChemoSen↑, RadioS↑, eff↝, *cardioP↑, *neuroP↑, *hepatoP↑, Apoptosis↑, MMP↓, Casp3↑, ROS↑, DNAdam↑, eff↑, BAX↑, BAD↑, FasL↑, Cyt‑c↑, Casp9↑, Casp8↑, TumCCA↑, P21↑, Smo↓, Gli1↓, JNK↑, ERK↓, MAPK↓, TRPM7↓, Wnt/(β-catenin)↓, BioAv↝, BioAv↑,
5890- CAR,    Carvacrol as a Prospective Regulator of Cancer Targets/Signalling Pathways
- Review, Var, NA
selectivity↑, TumCG↓, *Inflam↓, *antiOx↑, TumCCA↑, TumCMig↓, TumCI↓, angioG↓,
5927- CAR,    Neuroprotective Potential and Underlying Pharmacological Mechanism of Carvacrol for Alzheimer’s and Parkinson’s Diseases
- Review, AD, NA - Review, Park, NA
*memory↑, *cognitive↑, *ROS↓, *Inflam↓, *motorD↑, *toxicity↓, *TRPV3↑, *other↓, *antiOx↑, *LDL↓, *COX2↓, *PPARα↑, *NO↓, *AChE↓, *eff↑, *SOD↑, *Catalase↑, *neuroP↑, *BioAv↝, *BBB↑, *BioAv↑,
5932- CAR,    Carvacrol attenuates mucosal barrier impairment and tumorigenesis by regulating gut microbiome
- in-vivo, IBD, NA - in-vivo, Park, NA
*GutMicro↑, Risk↓, *Inflam↓, *antiOx↓, *ZO-1↑, *iNOS↓, *IL6↓, *NO↓, *PGE2↓, *memory↑, *TLR4↓, *NF-kB↓, *IBI↑, *CLDN3↑, *CLDN1↑, *MUC1↑, *OCLN↑, *iNOS↑, *COX2↓, *IFN-γ↓, IL1β↓, ADAM10?,
5926- CAR,    An Updated Review of Research into Carvacrol and Its Biological Activities
- Review, Nor, NA - Review, AD, NA - Review, asthmatic, NA
*Inflam↓, *antiOx↑, *neuroP↑, *BioAv↑, *toxicity↓, *Pain↓, *TRPV3↑, *NRF2↑, *Ca+2↑, *ATP↑, *5LO↓, *COX2↓, PGE2↓, *hepatoP↑, *AntiAg↑, *Diar↓, *cardioP↑, *other↝, *chemoPv↑, *cognitive↑, *AChE↓, *GastroP↑, *eff↑, *BChE↓, *CRP↓,
5925- CAR,    Neuroprotective effects of carvacrol against Alzheimer’s disease and other neurodegenerative diseases: A review
- Review, AD, NA - Review, Park, NA - Review, Stroke, NA
*Inflam↓, *antiOx↑, *AChE↓, *BBB↑, *cardioP↑, *neuroP↑, *memory↑, *TAC↑, *ROS↓, *lipid-P↓, *MDA↓, *SOD↑, *Catalase↑, *NRF2↑, *cognitive↑, *IL1β↓, *COX2↓, *TNF-α↓, *TLR4↓, *BDNF↑, *PKCδ↑, *5LO↓, *TRPM7↓, *GSH↑, *other↑, *Ferroptosis↓, *GPx4↑,
3871- Carno,    Unveiling the Hidden Therapeutic Potential of Carnosine, a Molecule with a Multimodal Mechanism of Action: A Position Paper
- Review, NA, NA
*ROS↓, *NO↓, *Inflam↓,
3872- Carno,    Carnosine Protects Macrophages against the Toxicity of Aβ1-42 Oligomers by Decreasing Oxidative Stress
- in-vitro, AD, NA
*antiOx↑, *Inflam↓, *Aβ↓, *neuroP↑, *ROS↓, *NO↓,
3869- Carno,    Carnosine, Small but Mighty—Prospect of Use as Functional Ingredient for Functional Food Formulation
- Review, AD, NA - Review, Stroke, NA
*ROS↓, *IronCh↑, *AntiAge↑, *antiOx↑, *Inflam↓, *neuroP↑, *lipid-P↓, *toxicity↓, *NOX4↓, *SOD↑, *HNE↓, *IL6↓, *TNF-α↓, *IL1β↓, *Sepsis↓, *eff↑, *GABA↝, *Aβ↓, Glycolysis↓, AntiTum↑, p‑Akt↓, TumCCA↑, angioG↓, VEGFR2/KDR/Flk1↓, NF-kB↓,
5914- Cats,    Induction of apoptosis by Uncaria tomentosa through reactive oxygen species production, cytochrome c release, and caspases activation in human leukemia cells
- in-vitro, AML, HL-60
*Inflam↓, eff↑, DNAdam↑, Cyt‑c↑, Casp3↑, PARP↑, Fas↑, proCasp8↑, cl‑BID↑, BAX↑, Bcl-xL↑, cl‑Mcl-1↑,
5913- Cats,    Cat's claw inhibits TNFalpha production and scavenges free radicals: role in cytoprotection
- Review, Nor, NA
*Inflam↓, *NF-kB↓, *DPPH↓, *TNF-α↓, *Imm↑,
5811- CBC,    The Potential of Cannabichromene (CBC) as a Therapeutic Agent
- Review, Var, NA
*eff?, *Half-Life↝, *Inflam↓,
6254- CBC/D,    Cynanchum auriculatum Royle ex Wight., Cynanchum bungei Decne. and Cynanchum wilfordii (Maxim.) Hemsl.: Current Research and Prospects
- Review, Var, NA
*neuroP↑, *Imm↑, *Inflam↓, CSCs↓, HH↓, Gli↓, AST↓, ALAT↓, MDA↓, hepatoP↑, *NRF2↑, *HO-1↑, NF-kB?, GSK‐3β↓, β-catenin/ZEB1↓, COX2↓, MMP2↑, MMP9↓, BioAv↑,
5964- CEL,    Celecoxib pathways: pharmacokinetics and pharmacodynamics
- Review, Var, NA
COX2↓, *Pain↓, *Inflam↓, Apoptosis↑, TumCCA↑, angioG↓, ER Stress↑, VEGF↓, MMP9↓, PDK1↓, Akt↓, CA↓, CardioT↑,
5954- CEL,    The molecular mechanisms of celecoxib in tumor development
- Review, Var, NA
TumCP↓, TumCMig↓, TumCI↓, COX2↓, p‑NF-kB↓, Akt↓, MMP2↓, MMP9↓, Apoptosis↑, mitResp↑, ER Stress↑, TumAuto↑, ChemoSen↑, Inflam↓, PGE2↓, chemoPv↑, toxicity↓, Risk↓, PI3K↓, RadioS↑, TumCMig↓, TumCI↓, cJun↓, Sp1/3/4↓, ROS↑, MMP↓, MPT↑, Ca+2↑, Glycolysis↓, ATP↓, CSCs↓, Wnt/(β-catenin)↓, EMT↓, toxicity↝,
5938- Cela,    Celastrol: A Review of Useful Strategies Overcoming its Limitation in Anticancer Application
- Review, Var, NA
AntiCan↑, BioAv↓, Apoptosis↑, TumAuto↑, TumCCA↑, TumMeta↓, angioG↓, Inflam↓, antiOx↑, ChemoSen↑, HSP90↓, ROS↑, RadioS↑, P53↑, NLRP3↓,
5941- Cela,    Celastrol inhibits migration and invasion through blocking the NF-κB pathway in ovarian cancer cells
- in-vitro, Ovarian, SKOV3 - in-vitro, Ovarian, OVCAR-3
TumCMig↓, TumCI↓, NF-kB↓, p65↓, MMP9↓, eff↑, AntiTum↑, Inflam↓, AntiDiabetic↑,
5952- Cela,    Celastrol attenuates Alzheimer’s disease-mediated learning and memory impairment by inhibiting endoplasmic reticulum stress-induced inflammation and oxidative stress
- in-vivo, AD, NA
*memory↑, *Inflam↓, *ROS↓, *ER Stress↓, *neuroP↑, *Dose↝, *MDA↓, *SOD↑, *Catalase↑, *Aβ↓, BACE↓, LRP1↑, RAGE↓,
5948- Cela,    Recent Trends in anti-tumor mechanisms and molecular targets of celastrol
TumCP↓, TumCCA↑, Apoptosis↑, TumAuto↑, TumCI↓, TumMeta↓, Imm↝, angioG↓, Cyt‑c↑, ROS↑, BAX↑, Casp3↑, Casp9↑, cl‑PARP↑, PrxII↓, ER Stress↑, mtDam↑, CHOP/DDIT3↑, Inflam↓, NF-kB↓, CXCR4↓, MMP9↓, IL6↓, TNF-α↓, HSP90↓, neuroP↑, STAT3↓, Prx↓, HO-1↑, eff↑, eff↑, BioAv↑, toxicity↑, CardioT↑, hepatoP↓,
2393- Cela,    Celastrol mitigates inflammation in sepsis by inhibiting the PKM2-dependent Warburg effect
- in-vivo, Sepsis, NA - in-vitro, Nor, RAW264.7
OS↑, PKM2↓, Glycolysis↓, Warburg↓, Inflam↓, HMGB1↓, ALAT↓, AST↓, TNF-α↓, IL1β↓, IL6↓,

Showing Research Papers: 201 to 250 of 1007
Prev Page 5 of 21 Next

* indicates research on normal cells as opposed to diseased cells
Total Research Paper Matches: 1007

Pathway results for Effect on Cancer / Diseased Cells:


Redox & Oxidative Stress(tgid=1) ⓘ

antiOx↑, 4,   GSH↓, 2,   HO-1↑, 1,   lipid-P↑, 1,   MDA↓, 2,   MDA↑, 1,   NADH↓, 1,   Prx↓, 1,   PrxII↓, 1,   ROS↑, 14,  

Mitochondria & Bioenergetics(tgid=3) ⓘ

ATP↓, 1,   MEK↓, 1,   mitResp↑, 1,   MMP↓, 9,   MPT↑, 2,   mtDam↑, 2,  

Core Metabolism/Glycolysis(tgid=4) ⓘ

ALAT↓, 2,   AMPK↑, 1,   Glycolysis↓, 3,   PDK1↓, 1,   PIK3CA↓, 1,   PKM2↓, 1,   SIRT1↓, 2,   Warburg↓, 2,  

Cell Death(tgid=5) ⓘ

Akt↓, 6,   p‑Akt↓, 1,   Apoptosis↓, 1,   Apoptosis↑, 13,   BAD↑, 1,   BAX↑, 5,   Bax:Bcl2↑, 2,   Bcl-2↓, 4,   Bcl-xL↑, 1,   cl‑BID↑, 1,   Casp↑, 3,   Casp3↓, 1,   Casp3↑, 7,   Casp7↑, 1,   Casp8↑, 2,   proCasp8↑, 1,   Casp9↑, 4,   Cyt‑c↑, 10,   FADD↑, 2,   Fap1↓, 1,   Fas↑, 2,   FasL↑, 1,   iNOS↓, 1,   JNK↑, 2,   p‑JNK↑, 1,   MAPK↓, 3,   cl‑Mcl-1↑, 1,   p38↑, 2,   p‑p38↑, 1,   TRPV1↑, 4,  

Kinase & Signal Transduction(tgid=6) ⓘ

Sp1/3/4↓, 1,  

Transcription & Epigenetics(tgid=7) ⓘ

cJun↓, 1,   tumCV↓, 2,  

Protein Folding & ER Stress(tgid=8) ⓘ

CHOP/DDIT3↑, 1,   ER Stress↑, 3,   HSP90↓, 2,  

Autophagy & Lysosomes(tgid=9) ⓘ

ATG5↑, 1,   LC3II↑, 1,   p62↑, 1,   TumAuto↑, 3,  

DNA Damage & Repair(tgid=10) ⓘ

DNAdam↑, 5,   P53↑, 5,   PARP↑, 2,   cl‑PARP↑, 4,   PCNA↓, 1,  

Cell Cycle & Senescence(tgid=11) ⓘ

CDK4↓, 2,   cycE/CCNE↓, 1,   P21↑, 3,   TumCCA↑, 10,  

Proliferation, Differentiation & Cell State(tgid=12) ⓘ

CSCs↓, 2,   EMT↓, 1,   ERK↓, 2,   p‑ERK↓, 1,   FOXO3↑, 1,   Gli↓, 1,   Gli1↓, 1,   GSK‐3β↓, 1,   HH↓, 1,   mTOR↓, 3,   NOTCH↓, 1,   PI3K↓, 5,   Smo↓, 1,   STAT3↓, 2,   TOP1↓, 1,   TOP2↓, 1,   TRPM7↓, 3,   TumCG↓, 3,   Wnt/(β-catenin)↓, 2,  

Migration(tgid=13) ⓘ

AXL↓, 1,   CA↓, 1,   Ca+2↑, 4,   i-Ca+2?, 1,   p‑Cofilin↑, 1,   E-cadherin↑, 1,   F-actin↓, 2,   Ki-67↓, 1,   LRP1↑, 1,   MMP2↓, 4,   MMP2↑, 1,   MMP9↓, 8,   N-cadherin↓, 1,   RAGE↓, 1,   TIMP2↑, 1,   TIMP3↑, 1,   TRIB3↑, 1,   TumCI↓, 7,   TumCMig↓, 8,   TumCP↓, 6,   TumMeta↓, 6,   ZEB2↓, 1,   β-catenin/ZEB1↓, 2,  

Angiogenesis & Vasculature(tgid=14) ⓘ

angioG↓, 7,   EGFR↓, 1,   Hif1a↓, 1,   VEGF↓, 4,   VEGFR2/KDR/Flk1↓, 1,  

Immune & Inflammatory Signaling(tgid=16) ⓘ

COX1↓, 1,   COX2↓, 5,   CXCR4↓, 1,   HMGB1↓, 1,   IL1β↓, 2,   IL6↓, 2,   Imm↝, 1,   Inflam↓, 8,   NF-kB?, 1,   NF-kB↓, 4,   p‑NF-kB↓, 1,   p65↓, 1,   PGE2↓, 2,   TNF-α↓, 3,  

Synaptic & Neurotransmission(tgid=18) ⓘ

ADAM10?, 1,  

Protein Aggregation(tgid=19) ⓘ

BACE↓, 1,   NLRP3↓, 1,  

Hormonal & Nuclear Receptors(tgid=20) ⓘ

CDK6↓, 1,  

Drug Metabolism & Resistance(tgid=21) ⓘ

BioAv↓, 3,   BioAv↑, 6,   BioAv↝, 2,   ChemoSen↑, 8,   Dose↝, 1,   eff↓, 1,   eff↑, 11,   eff↝, 1,   Half-Life↓, 2,   Half-Life↝, 1,   RadioS↑, 4,   selectivity↑, 8,  

Clinical Biomarkers(tgid=22) ⓘ

AFP↓, 2,   ALAT↓, 2,   AST↓, 3,   creat↓, 1,   EGFR↓, 1,   IL6↓, 2,   Ki-67↓, 1,   RAGE↓, 1,   TRIB3↑, 1,  

Functional Outcomes(tgid=23) ⓘ

AntiCan↓, 2,   AntiCan↑, 4,   AntiDiabetic↑, 2,   AntiTum↑, 3,   cardioP↑, 1,   CardioT↑, 2,   chemoP↑, 2,   chemoPv↑, 4,   hepatoP↓, 1,   hepatoP↑, 3,   neuroP↑, 2,   Obesity↓, 2,   OS↑, 2,   Pain↓, 1,   RenoP↑, 2,   Risk↓, 2,   toxicity↓, 2,   toxicity↑, 1,   toxicity↝, 1,   Weight↑, 1,  
Total Targets: 179

Pathway results for Effect on Normal Cells:


Redox & Oxidative Stress(tgid=1) ⓘ

antiOx↓, 1,   antiOx↑, 18,   Catalase↑, 7,   DPPH↓, 1,   Ferroptosis↓, 1,   GPx↑, 3,   GPx4↑, 1,   GSH↑, 6,   GSR↑, 4,   GSS↑, 1,   GSTA1↑, 1,   HNE↓, 1,   HO-1↑, 5,   Keap1↓, 1,   lipid-P↓, 8,   lipid-P↑, 1,   MDA↓, 7,   NOX4↓, 1,   NQO1↑, 1,   NRF2↑, 9,   ROS?, 1,   ROS↓, 16,   ROS↑, 1,   SOD↑, 9,   TAC↑, 2,   Trx↑, 1,   UCPs↑, 2,  

Metal & Cofactor Biology(tgid=2) ⓘ

IronCh↑, 1,  

Mitochondria & Bioenergetics(tgid=3) ⓘ

ATP↑, 2,   mitResp↑, 1,   MMP↑, 1,   MMP∅, 1,   mtDam↓, 1,   OCR↑, 1,  

Core Metabolism/Glycolysis(tgid=4) ⓘ

ALAT↓, 4,   AMPK↑, 2,   ECAR↓, 1,   FAO↑, 1,   FASN↓, 1,   LDH↓, 2,   LDHA↓, 2,   LDL↓, 1,   NADPH↓, 2,   PGM1?, 1,   PKM2↓, 3,   PPARα↑, 3,   PPARγ↑, 1,   SIRT1↑, 2,   Warburg↓, 1,  

Cell Death(tgid=5) ⓘ

Akt↑, 1,   p‑Akt↑, 1,   Apoptosis↓, 1,   Bax:Bcl2↓, 1,   Casp3∅, 1,   cl‑Casp3↓, 1,   Cyt‑c∅, 1,   Ferroptosis↓, 1,   iNOS↓, 1,   iNOS↑, 1,   MAPK↓, 1,   TRPV1↑, 5,  

Kinase & Signal Transduction(tgid=6) ⓘ

TRPV3↑, 2,  

Transcription & Epigenetics(tgid=7) ⓘ

other↓, 1,   other↑, 2,   other↝, 2,  

Protein Folding & ER Stress(tgid=8) ⓘ

ER Stress↓, 1,  

Proliferation, Differentiation & Cell State(tgid=12) ⓘ

GSK‐3β↑, 1,   PI3K↑, 1,   TRPM7↓, 1,   Wnt/(β-catenin)↓, 1,  

Migration(tgid=13) ⓘ

5LO↓, 2,   AntiAg↑, 4,   APP↓, 1,   Ca+2↑, 3,   CLDN1↑, 1,   MMP-10↝, 1,   MUC1↑, 1,   Na+↑, 1,   PKA↑, 1,   PKCδ↑, 1,   ZO-1↑, 1,  

Angiogenesis & Vasculature(tgid=14) ⓘ

angioG↓, 1,   eNOS↑, 1,   NO↓, 4,  

Barriers & Transport(tgid=15) ⓘ

BBB↓, 1,   BBB↑, 2,   CLDN3↑, 1,   GastroP↑, 1,   IBI↑, 1,   Na+↑, 1,   OCLN↑, 1,  

Immune & Inflammatory Signaling(tgid=16) ⓘ

COX2↓, 8,   CRP↓, 1,   IFN-γ↓, 2,   IL18↓, 1,   IL1β↓, 4,   IL6↓, 4,   Imm↑, 4,   Inflam↓, 39,   Inflam↑, 3,   NF-kB↓, 8,   p65↓, 1,   PGE2↓, 1,   TLR4↓, 2,   TNF-α↓, 7,  

Synaptic & Neurotransmission(tgid=18) ⓘ

AChE↓, 5,   ADAM10↑, 1,   BChE↓, 1,   BDNF↑, 1,   GABA↝, 1,   tau↓, 2,   p‑tau↓, 2,  

Protein Aggregation(tgid=19) ⓘ

Aβ↓, 6,   NLRP3↓, 1,  

Drug Metabolism & Resistance(tgid=21) ⓘ

BioAv↓, 2,   BioAv↑, 4,   BioAv↝, 2,   Dose↝, 2,   eff?, 1,   eff↑, 6,   Half-Life↓, 1,   Half-Life↝, 1,  

Clinical Biomarkers(tgid=22) ⓘ

ALAT↓, 4,   ALP↓, 2,   AST↓, 3,   CRP↓, 1,   GutMicro↑, 3,   IL6↓, 4,   LDH↓, 2,  

Functional Outcomes(tgid=23) ⓘ

AntiAge↑, 1,   AntiCan↑, 4,   AntiDiabetic↑, 1,   cardioP↑, 8,   chemoP↑, 1,   chemoPv↑, 2,   cognitive↑, 5,   hepatoP↑, 3,   memory↑, 6,   motorD↑, 1,   neuroP↑, 16,   Obesity↓, 3,   OS↑, 1,   Pain↓, 4,   RenoP↑, 2,   Risk↓, 2,   toxicity↓, 4,   Weight↓, 1,  

Infection & Microbiome(tgid=24) ⓘ

Bacteria↓, 5,   Diar↓, 1,   Sepsis↓, 3,  
Total Targets: 150

Scientific Paper Hit Count for: Inflam, inflammation
40 Curcumin
31 Magnetic Fields
30 Silymarin (Milk Thistle) silibinin
30 Quercetin
28 Thymoquinone
27 Hydrogen Gas
23 Resveratrol
18 Alpha-Lipoic-Acid
18 Berberine
18 Selenium NanoParticles
18 Fisetin
18 Rosmarinic acid
17 Lycopene
16 Ashwagandha(Withaferin A)
16 Ferulic acid
15 Capsaicin
15 Carvacrol
15 Sulforaphane (mainly Broccoli)
15 Urolithin
14 Propolis -bee glue
14 Emodin
13 Silver-NanoParticles
13 Beta-Caryophyllene
13 Eugenol
12 Apigenin (mainly Parsley)
12 Baicalein
12 Chlorogenic acid
12 Chrysin
11 Radiotherapy/Radiation
11 Cinnamon
11 Honokiol
10 Crocetin
10 Dandelion Root
10 EGCG (Epigallocatechin Gallate)
10 Pterostilbene
9 Selenite (Sodium)
9 Boron
9 Chemotherapy
9 Ginger/6-Shogaol/Gingerol
8 Astaxanthin
8 Boswellia (frankincense)
8 α-Bisabolol / Chamomile oil
8 Diclofenac
8 Fucoidan
8 Piperlongumine
8 Vitamin C (Ascorbic Acid)
8 Shikonin
7 Allicin (mainly Garlic)
7 Betulinic acid
7 Vitamin B3,Niacin
7 Butyrate
7 Centella asiatica / Gotu kola → asiaticoside
7 D-limonene
7 Gallic acid
6 1,8-Cineole
6 Artemisinin
6 Aspirin
6 Caffeic acid
6 Thymol-Thymus vulgaris
6 Garcinol
6 Magnolol
6 Piperine
6 Rutin
5 Folic Acid, Vit B9
5 Celastrol
5 chitosan
5 Chocolate
5 Coenzyme Q10
5 Ellagic acid
5 Shilajit/Fulvic Acid
5 Luteolin
5 Magnetic Field Rotating
5 Ursolic acid
4 Bacopa monnieri
4 Cisplatin
4 Caffeic Acid Phenethyl Ester (CAPE)
4 Cichoric acid / Chicoric acid
4 Hydroxycinnamic-acid
4 Carvone
4 Ginkgo biloba-EGb 761
4 Formononetin
4 Ginkgo biloba
4 Geraniol
4 Ginkgetin
4 Moringa oleifera
4 nicotinamide adenine dinucleotide
4 Nimbolide
4 Taurine
4 Vitamin B5,Pantothenic Acid
4 Vitamin D3
4 Vitamin K2
3 Anethole/trans-Anethole
3 Baicalin
3 Biochanin A
3 Vitamin B12
3 Bromelain
3 doxorubicin
3 Carnosine
3 Spermidine
3 Cucurbitacin
3 Date Fruit Extract
3 Docosahexaenoic Acid
3 eicosapentaenoic acid
3 diet Fermented Foods
3 Exercise
3 Gamma-aminobutyric acid
3 Genistein (soy isoflavone)
3 HydroxyCitric Acid
3 HydroxyTyrosol
3 Methylsulfonylmethane
3 α-Santalol/Sandalwood oil
3 Sulfasalazine
3 Vitamin B1/Thiamine
2 Anthocyanins
2 alpha Linolenic acid
2 Fennel Oil/Foeniculum vulgare
2 Melatonin
2 brusatol
2 borneol
2 Cat’s Claw
2 Celecoxib
2 Chlorophyllin
2 Choline
2 methotrexate
2 Selenium
2 Vitamin E
2 Galantamine
2 Huperzine A/Huperzia serrata
2 Lecithin
2 diet Short Term Fasting
2 Dipyridamole
2 Echinacea
2 Eurycomanone
2 flavonoids
2 Germanium Organic/Ge-132 / propagermanium (organogermanium)
2 Ginkgolide B
2 Ginseng
2 Orlistat
2 Potassium
2 Lutein
2 Methyl salicylate / Sweet Birch oil
2 Mushroom Lion’s Mane
2 Naringin
2 Oleocanthal
2 Phenylbutyrate
2 Phenethyl isothiocyanate
2 Phosphatidylserine
2 Salvia officinalis
2 Shankhpushpi
2 Salvia miltiorrhiza
2 Terpinen-4-ol / Tea Tree Oil
2 Aflavin-3,3′-digallate
2 Turmerones
1 2-DeoxyGlucose
1 5-Hydroxytryptophan
1 Astragalus
1 Acetyl-l-carnitine
1 Aloe anthraquinones
1 beta-glucans
1 xanthohumol
1 Cannabidiol
1 beta-carotene(VitA)
1 Vitamin B6,pyridoxine
1 Bifidobacterium
1 Brucea javanica
1 Bruteridin(bergamot juice)
1 Paclitaxel/Taxol
1 Carnosic acid
1 Cannabichromene
1 Cynanbungeigenin C (CBC) and D (CBD)
1 chaetocin
1 Prebiotic
1 Carica papaya leaf extract
1 Calorie Restriction Mimetics
1 Copper and Cu NanoParticles
1 Rivastigmine
1 Deguelin
1 Dihydrocaffeic Acid
1 Disulfiram
1 immunotherapy
1 Electrical Pulses
1 Evodiamine
1 Ascorbyl Palmitate
1 Flickering Light Stimulation
1 Iron
1 Galloflavin
1 Gambogic Acid
1 Ginkgolic acids
1 γ-linolenic acid (Borage Oil)
1 Germacranolide sesquiterpene lactone
1 Siegesbeckia glabrescens
1 hydrogen sulfide
1 Juglone
1 Licorice
1 Linalool
1 Zeaxanthin
1 5-fluorouracil
1 MCToil
1 Metformin
1 Neem
1 Oleuropein
1 Oregano
1 Peppermint
1 Propyl gallate
1 Psoralidin
1 Parthenolide
1 EMF
1 Radio Frequency
1 Aromatherapy
1 Gold NanoParticles
1 Sesame seeds and Oil
1 Silicic Acid
1 cetuximab
1 Terminalia bellirica
1 Thyme
1 Vitamin A, Retinoic Acid
1 Vitamin B2,Riboflavin
1 probiotics
1 Zinc
1 Zerumbone
Query results interpretion may depend on "conditions" listed in the research papers.
Such Conditions may include : 
  -low or high Dose
  -format for product, such as nano of lipid formations
  -different cell line effects
  -synergies with other products 
  -if effect was for normal or cancerous cells

Filter Conditions: Pro/AntiFlg:%  IllCat:%  CanType:%  Cells:%  prod#:%  Target#:953  State#:%  Dir#:%
  wNotes=0  sortOrder:rid,rpid

 

Home Page