eff Cancer Research Results

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Type:
Power to enhance an anti cancer effect
Scientific Papers found: Click to Expand⟱
2624- Ba,    Baicalein inhibition of hydrogen peroxide-induced apoptosis via ROS-dependent heme oxygenase 1 gene expression
- in-vitro, Nor, RAW264.7
*HO-1↑, *ERK↑, *ROS↓, *eff↑, *MMP↑, *Cyt‑c∅,
2290- Ba,    Research Progress of Scutellaria baicalensis in the Treatment of Gastrointestinal Cancer
- Review, GI, NA
p‑mTOR↓, p‑Akt↓, p‑IKKα↓, NF-kB↓, PI3K↓, Akt↓, ROCK1↓, GSK‐3β↓, CycB/CCNB1↓, cycD1/CCND1↓, cycA1/CCNA1↑, CDK4↓, P53↑, P21↑, TumCCA↑, MMP2↓, MMP9↓, EMT↓, Hif1a↓, Shh↓, PD-L1↓, STAT3↓, IL1β↓, IL2↓, IL6↓, PKM2↓, HDAC10↓, P-gp/ABCB1↓, Bcl-xL↓, eff↓, BioAv↓, BioAv↑,
5543- BBM,    Enhanced anti-metastatic and anti-tumorigenic efficacy of Berbamine loaded lipid nanoparticles in vivo
- in-vivo, Lung, B16-F10 - vitro+vivo, Lung, A549 - in-vitro, BC, MDA-MB-231
BioAv↓, Half-Life↓, eff↑, TumMeta↓, TumCP↓, TumCG↓, Apoptosis↑, TumCCA↑, MMP2↓, MMP9↓, VEGF↓, Bcl-2↓, eff↑, EPR↑,
5549- BBM,    Synergistic Anticancer Effect of a Combination of Berbamine and Arcyriaflavin A against Glioblastoma Stem-like Cells
- in-vitro, GBM, NA
eff?, tumCV↓, TumCG↓, ROS↑, P53↑, CSCs↓, CD133↓, ALDH1A1↓, Nanog↓, SOX2↓, OCT4↓, CDK1↓, CaMKII ↓, STAT3↓, Akt↓, ERK↓,
5550- BBM,  docx,  Chit,    Co-Delivery of Docetaxel and Berbamine by Chitosan/Sulfobutylether-β-Cyclodextrin Nanoparticles for Enhancing Bioavailability and Anticancer Activities
- in-vivo, Var, NA
eff↑, BioAv↑, Apoptosis↑, survivin↓,
5552- BBM,    Effects of berbamine against myocardial ischemia/reperfusion injury: Activation of the 5' adenosine monophosphate‐activated protein kinase/nuclear factor erythroid 2‐related factor pathway and changes in the mitochondrial state
- in-vivo, Stroke, NA
*eff↑, *ROS↓, *mtDam↓, *AMPK↑, *NRF2↑, *NADPH↑, *HO-1↑, *cardioP↑,
2022- BBR,  GoldNP,  Rad,    Berberine-loaded Janus gold mesoporous silica nanocarriers for chemo/radio/photothermal therapy of liver cancer and radiation-induced injury inhibition
- in-vitro, Liver, SMMC-7721 cell - in-vitro, Nor, HL7702
*toxicity↓, radioP↑, BioAv↑, AntiTum↑, selectivity↑, eff↑, chemoP↑,
2021- BBR,    Berberine: An Important Emphasis on Its Anticancer Effects through Modulation of Various Cell Signaling Pathways
- Review, NA, NA
*antiOx?, *Inflam↓, Apoptosis↑, TumCCA↑, BAX↑, Synergy↑, VEGF↓, PI3K↓, Akt↓, mTOR↓, Telomerase↓, β-catenin/ZEB1↓, Wnt↓, EGFR↓, AP-1↓, NF-kB↓, COX2/PTGS2↑, NRF2↓, RadioS↑, STAT3↓, ERK↓, AR↓, ROS↑, eff↑, selectivity↑, selectivity↑, BioAv↓, DNMT1↓, cMyc↓,
1385- BBR,  5-FU,    Low-Dose Berberine Attenuates the Anti-Breast Cancer Activity of Chemotherapeutic Agents via Induction of Autophagy and Antioxidation
- in-vitro, BC, MCF7 - in-vitro, BC, MDA-MB-231
eff↓, ROS↑, TumCP↑, NRF2↑, ChemoSen↓,
1390- BBR,  Rad,    Berberine Inhibited Radioresistant Effects and Enhanced Anti-Tumor Effects in the Irradiated-Human Prostate Cancer Cells
- in-vitro, Pca, PC3
RadioS↑, Apoptosis↑, ROS↑, eff↑, BAX↑, Casp3↑, P53↑, p38↑, JNK↑, Bcl-2↓, ERK↓, HO-1↓,
1374- BBR,  PDT,    Berberine associated photodynamic therapy promotes autophagy and apoptosis via ROS generation in renal carcinoma cells
- in-vitro, RCC, 786-O - in-vitro, RCC, HK-2
ROS↑, TumAuto↑, Apoptosis↑, Casp3↑, eff↑,
1378- BBR,    Berberine induces non-small cell lung cancer apoptosis via the activation of the ROS/ASK1/JNK pathway
- in-vitro, Lung, NA
Apoptosis↑, Casp3↑, Cyt‑c↑, MMP↓, p‑JNK↑, eff↓,
1379- BBR,    Berberine derivative DCZ0358 induce oxidative damage by ROS-mediated JNK signaling in DLBCL cells
- in-vitro, lymphoma, NA
TumCP↓, CDK4↓, CDK6↓, cycD1/CCND1↓, TumCCA↑, MMP↓, Ca+2↑, ATP↓, mtDam↑, Apoptosis↑, ROS↑, JNK↑, eff↓,
1402- BBR,    Berberine-induced apoptosis in human glioblastoma T98G cells is mediated by endoplasmic reticulum stress accompanying reactive oxygen species and mitochondrial dysfunction
- in-vitro, GBM, T98G
tumCV↓, ROS↑, Ca+2↑, ER Stress↑, eff↓, Bax:Bcl2↑, MMP↓, Casp9↑, Casp3↑, cl‑PARP↑,
1404- BBR,    Berberine-induced apoptosis in human prostate cancer cells is initiated by reactive oxygen species generation
- in-vitro, Pca, PC3
Apoptosis↑, *Apoptosis∅, MMP↓, cl‑Casp3↑, cl‑Casp9↑, cl‑PARP↑, ROS↑, eff↓, Cyt‑c↑,
2689- BBR,    Berberine protects against glutamate-induced oxidative stress and apoptosis in PC12 and N2a cells
- in-vitro, Nor, PC12 - in-vitro, AD, NA - in-vitro, Stroke, NA
*ROS↓, *lipid-P↓, *DNAdam↓, *GSH↑, *SOD↑, *eff↑, *cl‑Casp3↓, *BAX↓, *neuroP↑, *Dose↝, *Ca+2↓,
2678- BBR,    Berberine as a Potential Agent for the Treatment of Colorectal Cancer
- Review, CRC, NA
*Inflam↓, *antiOx↑, *cardioP↑, *neuroP↑, TumCCA↑, cycD1/CCND1↓, cycE/CCNE↓, CDC2↓, AMPK↝, mTOR↝, Casp8↑, Casp9↑, Cyt‑c↑, TumCMig↓, TumCI↓, EMT↓, MMPs↓, E-cadherin↓, Telomerase↓, *toxicity↓, GRP78/BiP↓, EGFR↓, CDK4↓, COX2/PTGS2↓, PGE2↓, p‑JAK2↓, p‑STAT3↓, MMP2↓, MMP9↓, GutMicro↑, eff↝, *BioAv↓, BioAv↑,
2674- BBR,    Berberine: A novel therapeutic strategy for cancer
- Review, Var, NA - Review, IBD, NA
Inflam↓, AntiCan↑, Apoptosis↑, TumAuto↑, TumCCA↑, TumMeta↓, TumCI↓, eff↑, eff↑, CD4+↓, TNF-α↓, IL1↓, BioAv↓, BioAv↓, other↓, AMPK↑, MAPK↓, NF-kB↓, IL6↓, MCP1/CCL2↓, PGE2↓, COX2/PTGS2↓, *ROS↓, *antiOx↑, *GPx↑, *Catalase↑, AntiTum↑, TumCP↓, angioG↓, Fas↑, FasL↑, ROS↑, ATM↑, P53↑, RB1↑, Casp9↑, Casp8↑, Casp3↓, BAX↑, Bcl-2↓, Bcl-xL↓, IAP1↓, XIAP↓, survivin↓, MMP2↓, MMP9↓, CycB/CCNB1↓, CDC25↓, CDC25↓, Cyt‑c↑, MMP↓, RenoP↑, mTOR↓, MDM2↓, LC3II↑, ERK↓, COX2/PTGS2↓, MMP3↓, TGF-β↓, EMT↑, ROCK1↓, FAK↓, RAS↓, Rho↓, NF-kB↓, uPA↓, MMP1↓, MMP13↓, ChemoSen↑,
2686- BBR,    Effects of resveratrol, curcumin, berberine and other nutraceuticals on aging, cancer development, cancer stem cells and microRNAs
- Review, Nor, NA
Inflam↓, IL6↓, MCP1/CCL2↓, COX2/PTGS2↓, PGE2↓, MMP2↓, MMP9↓, DNAdam↑, eff↝, Telomerase↓, Bcl-2↓, AMPK↑, ROS↑, MMP↓, ATP↓, p‑mTORC1↓, p‑S6K↓, ERK↓, PI3K↓, PTEN↑, Akt↓, Raf↓, MEK↓, Dose↓, Dose↑, selectivity↑, TumCCA↑, Synergy↑, EGFR↓, Glycolysis↓, Dose?, p27/CDKN1B↑, CDK2↓, CDK4↓, cycD1/CCND1↓, cycE/CCNE↓, Bax:Bcl2↑, Casp3↑, Casp9↑, VEGFR2/KDR/Flk1↓, ChemoSen↑, Synergy↑, Synergy↑, PGE2↓, JAK2↓, STAT3↓, CXCR4↓, CCR7↓, uPA↓, CSCs↓, EMT↓, Diff↓, CD133↓, Nestin↓, n-MYC↓, NOTCH↓, SOX2↓, Hif1a↓, VEGF↓, RadioS↑,
3754- BBR,  CUR,  EGCG,  Hup,    Traditional Chinese medicinal herbs as potential AChE inhibitors for anti-Alzheimer’s disease: A review
- Review, AD, NA
*AChE↓, *Aβ↓, *LDL↓, *RenoP↑, *BChE↓, *eff↑, *BACE/β-secretase↓, *AChE↓, *Synergy↑,
4275- BBR,    Pharmacological effects of berberine on mood disorders
- Review, AD, NA
*antiOx↑, *Inflam↓, *hepatoP↑, *eff↑, *5HT↑, *Mood↑, *BDNF↑,
1473- BCA,  SFN,    An Insight on Synergistic Anti-cancer Efficacy of Biochanin A and Sulforaphane Combination Against Breast Cancer
- in-vitro, BC, MCF7
eff↑, ROS↑, other↑, ERK↓, Apoptosis↑,
6497- BCP,  Cisplatin,    Beta-Caryophyllene Enhances the Anti-Tumor Activity of Cisplatin in Lung Cancer Cell Lines through Regulating Cell Cycle and Apoptosis Signaling Molecules
- in-vitro, Lung, NA
TumCG↓, TumCP↓, Apoptosis↑, toxicity↓, ChemoSen↑, P21↑, Bcl-xL↑, Bcl-2↓, EMT↓, E-cadherin↑, eff↑, MMP↓,
6502- BCP,    Enhanced Oral Bioavailability of β-Caryophyllene in Healthy Subjects Using the VESIsorb® Formulation Technology, a Novel Self-Emulsifying Drug Delivery System (SEDDS)
- Study, Nor, NA
*BioAv↑, *BioAv↓, *BioAv↓, *eff↑,
5510- bemA,    Combined inhibition of ACLY and CDK4/6 reduces cancer cell growth and invasion
- in-vitro, BC, MDA-MB-231 - in-vitro, PC, NA
eff↑, Apoptosis↑, TumCI↓, ACLY↓, LDL↓, eff↑, TumCP↓,
5511- bemA,    Inhibition of ACLY overcomes cancer immunotherapy resistance via polyunsaturated fatty acids peroxidation and cGAS-STING activation
- in-vitro, Var, NA
ACLY↓, PD-L1↑, mtDam↑, cGAS–STING↑, LDL↓, eff↑,
5513- bemA,    ACLY inhibition promotes tumour immunity and suppresses liver cancer
- in-vitro, Liver, NA
ACLY↓, AMPK↑, eff↑, other↝, eff↝,
5591- BetA,    Advances and challenges in betulinic acid therapeutics and delivery systems for breast cancer prevention and treatment
- Review, BC, NA
BioAv↓, BioAv↑, selectivity↑, eff↑, angioG↓, *antiOx↑, *Inflam↓, MMP↓, Bcl-2↓, BAX↑, Casp9↑, Casp3↑, GRP78/BiP?, ER Stress↑, PERK↑, CHOP/DDIT3↑, ChemoSen↑, SESN2↑, ROS↑, MOMP↓, MAPK↑, Cyt‑c↑, AIF↑, STAT3↓, FAK↓, TIMP2↑, TumCMig↓, TumCI↓, Sp1/3/4↓, TumCCA↑, DNAdam↑,
5583- BetA,    Selective cytotoxicity of betulinic acid on tumor cell lines, but not on normal cells
- vitro+vivo, Var, NA
ROS↑, Bcl-2↓, BAX↑, TOP1↝, eff↝, toxicity↓, toxicity↓, selectivity↑,
2718- BetA,    The anti-cancer effect of betulinic acid in u937 human leukemia cells is mediated through ROS-dependent cell cycle arrest and apoptosis
- in-vitro, AML, U937
TumCCA↑, Apoptosis↑, i-ROS↑, cycA1/CCNA1↓, CycB/CCNB1↓, P21↑, Cyt‑c↑, MMP↓, Bax:Bcl2↑, Casp9↑, Casp3↑, PARP↓, eff↓, *antiOx↑, *Inflam↓, *hepatoP↑, selectivity↑, NF-kB↓, *ROS↓,
2717- BetA,    Betulinic Acid Induces ROS-Dependent Apoptosis and S-Phase Arrest by Inhibiting the NF-κB Pathway in Human Multiple Myeloma
- in-vitro, Melanoma, U266 - in-vivo, Melanoma, NA - in-vitro, Melanoma, RPMI-8226
Apoptosis↑, TumCCA↑, MMP↓, ROS↑, eff↓, NF-kB↓, Cyt‑c↑, Casp3↑, Casp8↑, Casp9↑, cl‑PARP1↑, MDA↑, SOD↓, SOD2↓, GCLM↓, GSTA1↓, FTH1↓, GSTs↓, TumVol↓,
2737- BetA,    Multiple molecular targets in breast cancer therapy by betulinic acid
- Review, Var, NA
TumCP↓, Cyc↓, TOP1↓, TumCCA↑, angioG↓, NF-kB↓, Sp1/3/4↓, VEGF↓, MMPs↓, ChemoSen↑, eff↑, MMP↓, ROS↑, Bcl-2↓, Bcl-xL↓, Mcl-1↓, lipid-P↑, RadioS↑, Synergy↑,
2728- BetA,    Betulinic acid as new activator of NF-kappaB: molecular mechanisms and implications for cancer therapy
- in-vitro, Var, NA
NF-kB↑, IKKα↑, eff↓,
2730- BetA,    Betulinic acid induces autophagy-dependent apoptosis via Bmi-1/ROS/AMPK-mTOR-ULK1 axis in human bladder cancer cells
- in-vitro, Bladder, T24/HTB-9
tumCV↓, TumCP↓, TumCMig↓, Casp↑, TumAuto↑, LC3B-II↑, p‑AMPK↑, mTOR↓, BMI1↓, ROS↑, eff↓,
2733- BetA,    Betulinic Acid Inhibits Cell Proliferation in Human Oral Squamous Cell Carcinoma via Modulating ROS-Regulated p53 Signaling
- in-vitro, Oral, KB - in-vivo, NA, NA
TumCP↓, TumVol↓, mt-Apoptosis↑, Casp3↑, Casp9↑, BAX↑, Bcl-2↑, OCR↓, TumCCA↑, ROS↑, eff↓, P53↑, STAT3↓, cycD1/CCND1↑,
2771- BetA,    Cardioprotective Effect of Betulinic Acid on Myocardial Ischemia Reperfusion Injury in Rats
- in-vivo, Nor, NA - in-vivo, Stroke, NA
*cardioP↑, *LDH↓, eff↑,
2755- BetA,    Cytotoxic Potential of Betulinic Acid Fatty Esters and Their Liposomal Formulations: Targeting Breast, Colon, and Lung Cancer Cell Lines
- in-vitro, Colon, HT29 - in-vitro, BC, MCF7 - in-vitro, Lung, H460
eff↑, Casp3↑, Casp7↑, NF-kB↓,
2753- BetA,    Betulinic acid induces apoptosis by regulating PI3K/Akt signaling and mitochondrial pathways in human cervical cancer cells
- in-vitro, Cerv, HeLa
PI3K↓, p‑Akt↓, ROS↑, TumCCA↑, p27/CDKN1B↑, P21↑, mt-Apoptosis↑, BAD↑, Casp9↑, MMP↓, eff↓,
5561- betaCar,    Carotenoid Supplementation for Alleviating the Symptoms of Alzheimer’s Disease
- Review, AD, NA
*ROS↓, *cognitive↑, *BBB↑, *lipid-P↓, *eff↑,
5563- betaCar,    Carotenoid Supplementation for Alleviating the Symptoms of Alzheimer's Disease
- Review, AD, NA
*BBB↑, *lipid-P↓, *eff↑, *cognitive↑,
3988- betaCar,  Lut,  Zeax,    Effects of egg consumption on carotenoid absorption from co-consumed, raw vegetables
- Trial, AD, NA
*eff↑, *Synergy↑, *Synergy↑,
5518- BEV,  Chemo,    Bevacizumab
- Review, Var, NA - Review, AMD, NA
Dose↝, other↑, VEGF↓, eff↑, Half-Life↑,
5517- BEV,    Exploring the Immunological Mechanisms Underlying the Anti-vascular Endothelial Growth Factor Activity in Tumors
- Review, Var, NA
VEGF↓, Imm↑, eff↑,
5516- BEV,  immuno,  Chemo,    Targeting vascular normalization: a promising strategy to improve immune–vascular crosstalk in cancer immunotherapy
- Review, Var, NA
OS↑, eff↑,
5594- BEV,  immuno,    Serum VEGF-A as a biomarker for the addition of bevacizumab to chemo-immunotherapy in metastatic NSCLC
- Human, NSCLC, NA
eff↑,
5725- BF,  TMZ,    Bufalin Induces Apoptosis and Improves the Sensitivity of Human Glioma Stem-Like Cells to Temozolamide
- in-vitro, GBM, NA
TumCG↓, TumCP↓, CSCs↓, cl‑Casp3↑, PARP↑, Telomerase↓, eff↑,
5726- BF,    Bufalin exerts antitumor effects in neuroblastoma via the induction of reactive oxygen species-mediated apoptosis by targeting the electron transport chain
- Review, neuroblastoma, SK-N-BE
Apoptosis↑, TumCP↓, TumCMig↓, MMP↓, ROS↑, ETC↓, Bcl-2↓, BAX↑, cl‑Casp3↑, cl‑PARP↑, eff↓, TumCG↓, Ki-67↓, PCNA↓,
5622- Bif,    Bifidobacterium bifidum strains synergize with immune checkpoint inhibitors to reduce tumour burden in mice
- in-vivo, Var, NA
eff↑, Imm↑, IFN-γ↑,
5623- Bif,    Bifidobacterium breve predicts the efficacy of anti-PD-1 immunotherapy combined with chemotherapy in Chinese NSCLC patients
- Study, NSCLC, NA
GutMicro↑, OS↑, eff↑,
5625- Bif,  immuno,    The gut microbiome and cancer response to immune checkpoint inhibitors
- Review, Var, NA
eff↑, eff↓,

Showing Research Papers: 201 to 250 of 1416
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* indicates research on normal cells as opposed to diseased cells
Total Research Paper Matches: 1416

Pathway results for Effect on Cancer / Diseased Cells:


NA, unassigned(tgid=0) ⓘ

NA↑, 2,  

Redox & Oxidative Stress(tgid=1) ⓘ

antiOx↓, 4,   antiOx↑, 21,   ARE/EpRE↑, 1,   Catalase↓, 12,   Catalase↑, 4,   Catalase∅, 1,   Copper↓, 1,   CoQ10↑, 1,   cystine↓, 1,   DJ-1↓, 1,   ENOX2↓, 2,   ENOX2↑, 1,   Fenton↑, 16,   GCLM↓, 1,   GPx↓, 8,   GPx↑, 5,   GPx1↓, 1,   GPx1↑, 1,   GPx4↓, 16,   GSH↓, 74,   GSH↑, 3,   GSH↝, 1,   GSH∅, 1,   i-GSH∅, 1,   mt-GSH↓, 1,   GSH/GSSG↓, 12,   GSR↓, 3,   GSSG↓, 1,   ox-GSSG↑, 1,   GSTs↓, 2,   GSTs↑, 2,   GSTs∅, 1,   H2O2?, 1,   H2O2↑, 17,   e-H2O2↓, 1,   i-H2O2↑, 1,   i-H2O2∅, 1,   mt-H2O2↑, 1,   HO-1↓, 8,   HO-1↑, 14,   HO-2↓, 1,   HO-2↑, 1,   hyperG↓, 1,   Iron↓, 1,   Iron↑, 11,   Iron↝, 2,   i-Iron↑, 2,   c-Iron↑, 1,   Keap1↓, 1,   Keap1↑, 1,   lipid-P?, 1,   lipid-P↓, 4,   lipid-P↑, 40,   MDA↓, 3,   MDA↑, 11,   MPO↓, 1,   NADH↑, 1,   NADHdeh?, 1,   NADPH/NADP+↓, 1,   NQO1↓, 2,   NQO1↑, 1,   Nrf1↑, 2,   NRF2↓, 17,   NRF2↑, 20,   NRF2↝, 3,   p‑NRF2↑, 1,   Prx↓, 1,   Prx3↑, 1,   Prx4↑, 1,   Prx6↑, 2,   PrxII↓, 1,   PYCR1↓, 1,   RNS↑, 2,   ROS?, 5,   ROS↓, 23,   ROS↑, 555,   ROS⇅, 7,   ROS↝, 5,   ROS∅, 1,   i-ROS↓, 1,   i-ROS↑, 6,   mt-ROS↑, 18,   RPM↑, 1,   SOD↓, 18,   SOD↑, 6,   mt-SOD↑, 1,   SOD1↓, 3,   SOD1↑, 2,   SOD2↓, 5,   SOD2↑, 4,   TAC↓, 3,   Thiols↓, 3,   i-Thiols↓, 1,   Trx↓, 6,   Trx↑, 1,   Trx1↓, 1,   ox-Trx1↑, 1,   Trx2↓, 1,   TrxR↓, 30,   TrxR↑, 1,   TrxR1↓, 10,   TrxR1↑, 1,   VitC↓, 1,   VitE↓, 1,   xCT/SLC7A11↓, 6,   xCT/SLC7A11↑, 1,  

Metal & Cofactor Biology(tgid=2) ⓘ

Ferritin↓, 5,   Ferritin↑, 1,   FTH1↓, 3,   IronCh↑, 4,   IRP1↑, 1,   Mets↑, 1,   NCOA4↑, 2,   Tf↓, 1,   TfR1/CD71↑, 1,  

Mitochondria & Bioenergetics(tgid=3) ⓘ

ADP:ATP↑, 1,   CDC2↓, 3,   CDC25↓, 9,   CDC25↑, 2,   compI↓, 6,   compII↓, 1,   compIII↓, 1,   compIII↑, 1,   EGF↓, 1,   ETC↓, 10,   ETC↝, 1,   HSP60/HSPD1↑, 1,   Insulin↓, 4,   MCU↓, 1,   mitResp↓, 8,   mitResp↑, 2,   MKK7↓, 1,   mtDam↑, 45,   OCR↓, 13,   OCR↑, 3,   mt-OCR↓, 1,   OXPHOS↓, 9,   OXPHOS↑, 6,   OXPHOS⇅, 1,   OXPHOS↝, 3,   mt-OXPHOS↑, 2,   PDH↓, 4,   PDH↑, 1,   p‑PDH↓, 1,   PGC-1α↑, 4,   PINK1↑, 4,   SDH↓, 3,   SIRT3↓, 1,   SIRT3↑, 1,   TrxR2↓, 1,  

Core Metabolism/Glycolysis(tgid=4) ⓘ

12LOX?, 1,   12LOX↓, 3,   5LO↓, 4,   ACC↓, 2,   ACC↑, 1,   p‑ACC↑, 1,   ACLY↓, 7,   p‑ACLY↓, 1,   ACSL4↑, 2,   adiP↑, 2,   ADO↓, 1,   ALAT↓, 2,   ALAT∅, 1,   ALDOA↓, 2,   AMP↑, 1,   AMPK↑, 25,   AMPK↝, 1,   p‑AMPK↑, 3,   ATP↓, 43,   ATP↑, 1,   ATP∅, 1,   i-ATP↓, 1,   i-ATP↑, 1,   Buty↑, 2,   CAIX/CA9↓, 2,   citrate↓, 1,   CPT1A↓, 1,   CRM↑, 1,   CRM↝, 1,   ECAR↓, 6,   ECAR↝, 1,   ENO1↓, 3,   FABP4↓, 1,   FAO↑, 1,   FASN↓, 3,   FASN↑, 2,   FBPase↑, 1,   GAPDH↓, 3,   GLS↓, 1,   glucoNG↑, 1,   glucose↓, 2,   glucose↑, 1,   glucose∅, 1,   GlucoseCon↓, 15,   GlucoseCon↑, 2,   GlucoseCon∅, 1,   glut↓, 1,   glyC↓, 1,   Glycolysis↓, 51,   Glycolysis↑, 3,   Glycolysis↝, 1,   GSK‐3β↓, 10,   GSK‐3β↑, 4,   p‑GSK‐3β↓, 4,   p‑GSK‐3β↑, 1,   Histones↑, 1,   HK1↓, 1,   HK2?, 1,   HK2↓, 24,   HK2↑, 1,   HK2∅, 1,   HMG-CoA↓, 3,   KeyT↑, 1,   lactateProd↓, 26,   lactateProd↑, 4,   lactateProd∅, 1,   e-lactateProd↓, 1,   LDHA↓, 12,   LDHA↑, 1,   LDHA∅, 1,   LDL↓, 4,   lipidLev↓, 1,   lipidLev↑, 1,   lipoGen↓, 1,   MCT4↓, 1,   NAD↓, 2,   NADPH↓, 8,   NADPH↑, 1,   NH3↓, 1,   PDK1 / PDPK1?, 2,   PDK1 / PDPK1↓, 9,   PDKs↓, 4,   PFK↓, 6,   PFK1↓, 2,   PFK2?, 1,   PFK2↓, 1,   PFKP↓, 2,   PGK1↓, 2,   PGM1↓, 1,   PGM1∅, 1,   PKM2↓, 20,   p‑PKM2↓, 1,   polyA↓, 1,   PPP↓, 2,   PPP↑, 1,   Pyruv↓, 1,   SCD1↓, 3,   SCFAs↑, 2,   SIRT1↓, 9,   SIRT1↑, 6,   SREBP1/SREBF1↓, 2,   SREBP2↓, 1,   TCA?, 1,   TCA↓, 2,   TCA↑, 2,   TCA↝, 1,   TS↓, 3,   UGDH↓, 2,   Warburg↓, 11,   Warburg↑, 1,   β-oxidation↓, 1,  

Cell Death(tgid=5) ⓘ

AIF↑, 18,   APAF1↑, 5,   Apoptosis?, 1,   Apoptosis↓, 12,   Apoptosis↑, 357,   mt-Apoptosis↑, 6,   ASC↓, 1,   ASK1↑, 2,   p‑ASK1↑, 1,   aSmase↑, 1,   BAD↓, 1,   BAD↑, 10,   Bak↓, 1,   Bak↑, 11,   BAX↓, 6,   BAX↑, 145,   Bax:Bcl2↑, 38,   Bcl-2↓, 155,   Bcl-2↑, 4,   Bcl-2∅, 1,   Bcl-xL↓, 38,   Bcl-xL↑, 3,   BID↓, 1,   BID↑, 7,   p‑BID↓, 1,   cl‑BID↑, 2,   BIM↑, 7,   BNIP3?, 2,   BNIP3↑, 1,   BNIP3↝, 1,   Casp↓, 1,   Casp↑, 55,   cl‑Casp↑, 1,   Casp1↓, 1,   Casp12?, 1,   Casp12↑, 2,   pro‑Casp12↓, 1,   Casp2↑, 3,   Casp3↓, 4,   Casp3↑, 176,   cl‑Casp3↑, 51,   cl‑Casp3∅, 1,   proCasp3↓, 3,   proCasp3↑, 3,   CASP4↑, 1,   Casp6↑, 1,   Casp7↑, 20,   cl‑Casp7↑, 5,   Casp8↓, 2,   Casp8↑, 41,   Casp8∅, 2,   cl‑Casp8↑, 4,   proCasp8↑, 2,   Casp9↓, 1,   Casp9↑, 105,   cl‑Casp9↓, 1,   cl‑Casp9↑, 20,   proCasp9↓, 1,   proCasp9↑, 2,   cFLIP↓, 5,   Cupro↑, 3,   Cyt‑c↓, 1,   Cyt‑c↑, 121,   Cyt‑c↝, 1,   Diablo↑, 5,   DIDO1/DIO-1↑, 1,   DR5↑, 23,   Endon↑, 1,   FADD↑, 5,   Fap1↓, 1,   Fas↓, 2,   Fas↑, 15,   FasL↓, 1,   FasL↑, 13,   FasL⇅, 1,   Ferroptosis↓, 4,   Ferroptosis↑, 30,   GranB/GZMB↑, 1,   GranB/GZMB↝, 1,   GSDMD↑, 3,   GSDME↑, 1,   cl‑GSDME↑, 1,   GSDME-N↑, 2,   IAP1↓, 7,   IAP2/BIRC3↓, 3,   ICD↑, 5,   iNOS↓, 9,   iNOS↑, 1,   Mcl-1↓, 24,   p‑Mcl-1↓, 1,   cl‑Mcl-1↑, 1,   MDM2↓, 13,   MDM2↑, 1,   p‑MDM2↓, 1,   MLKL↑, 3,   p‑MLKL↓, 1,   MOMP↓, 2,   MOMP↑, 5,   Necroptosis↑, 7,   necrosis↑, 10,   NOXA↑, 6,   p38↓, 3,   p38↑, 25,   p‑p38↓, 1,   p‑p38↑, 12,   Paraptosis↑, 4,   Perforin↑, 1,   Perforin↝, 1,   PUMA↑, 7,   Pyro↑, 9,   RIP1↓, 2,   RIP1↑, 2,   RIP3↑, 3,   p‑RIP3↑, 2,   SK↓, 1,   survivin↓, 50,   TRAIL↑, 5,   TumCD↓, 4,   TumCD↑, 55,   TumCD∅, 2,   TUNEL↑, 1,   XIAP↓, 22,   YAP/TEAD↓, 7,   YAP/TEAD↑, 1,  

Kinase & Signal Transduction(tgid=6) ⓘ

ABL1↓, 1,   Akt↓, 115,   Akt↑, 6,   p‑Akt↓, 37,   p‑Akt↑, 4,   AKT1↓, 2,   AMPKα↑, 4,   BRAF↓, 1,   CaMKII ↓, 2,   CaMKII ↑, 1,   CK2↓, 2,   cMET↓, 2,   CREB↑, 1,   cSrc↓, 1,   DDIT4↑, 1,   EGFR↓, 24,   EGFR↑, 2,   p‑EGFR↓, 1,   ERK↓, 32,   ERK↑, 12,   p‑ERK↓, 12,   p‑ERK↑, 8,   e-ERK↑, 1,   FOXD3↑, 1,   HCAR2↑, 1,   HER2/EBBR2↓, 8,   HGF/c-Met↓, 1,   Hippo↓, 2,   Hippo↝, 1,   IGF-1R↓, 2,   IGFR↓, 2,   IKKα↓, 7,   IKKα↑, 3,   p‑IKKα↓, 1,   IκB↑, 2,   p‑IκB↓, 2,   JAK↓, 2,   JAK1?, 1,   JAK1↓, 1,   p‑JAK1↓, 1,   JAK2↓, 8,   p‑JAK2↓, 5,   JNK↓, 6,   JNK↑, 33,   p‑JNK↑, 13,   LATS1↓, 1,   MAPK↓, 22,   MAPK↑, 16,   p‑MAPK↓, 1,   p‑MAPK↑, 6,   MEK↓, 2,   p‑MEK↓, 2,   p‑MEK↑, 1,   MKK4↓, 1,   MKP1↓, 1,   MKP2↓, 1,   Mst1↑, 1,   mTOR↓, 59,   mTOR↑, 3,   mTOR⇅, 1,   mTOR↝, 1,   p‑mTOR↓, 12,   mTORC2↓, 1,   mTORC2↑, 1,   p70S6↓, 2,   P70S6K↓, 2,   p‑P70S6K↓, 2,   p85S6K↓, 1,   p‑PDGFR-BB↓, 1,   PI3K↓, 82,   PI3K↑, 5,   p‑PI3K↓, 4,   PI3K/Akt↓, 1,   PIK3CA↓, 1,   PIK3CA↑, 1,   PKA↓, 3,   PKA↑, 1,   PKCδ↓, 5,   PTEN↓, 1,   PTEN↑, 15,   p‑PTEN↓, 1,   Raf↓, 3,   RAS↓, 4,   p‑RSK↑, 1,   p‑S6K↓, 1,   Sp1/3/4↓, 7,   Src↓, 2,   p‑Src↓, 2,   STAT↓, 4,   STAT3↓, 54,   STAT3↑, 3,   STAT3⇅, 1,   STAT3↝, 1,   p‑STAT3↓, 15,   p‑STAT3↑, 2,   mt-STAT3↓, 1,   STAT6↓, 2,   p‑STAT6↓, 1,   p‑STK11/LKB1↑, 1,   TSC2↑, 1,  

Transcription & Epigenetics(tgid=7) ⓘ

AntiThr↑, 1,   ATF3↑, 1,   ATF4↑, 10,   ATF4↝, 1,   CBP↓, 1,   ChrMod↑, 1,   cJun↓, 2,   cJun↑, 3,   p‑cJun↑, 1,   cMyc↓, 31,   cMyc↑, 1,   DNMT1↓, 4,   DNMT1↑, 1,   DNMT3A↓, 1,   DNMTs↓, 5,   EZH2↓, 1,   FOXO1↑, 2,   FOXO3↓, 2,   FOXO3↑, 5,   FOXO4↑, 2,   H3↓, 3,   p‑H3↓, 1,   p‑H3↑, 1,   ac‑H3↓, 1,   ac‑H3↑, 2,   H3K27ac∅, 1,   H4↓, 1,   ac‑H4↓, 1,   ac‑H4↑, 1,   HATs↓, 1,   HATs↑, 1,   HDAC↓, 26,   HDAC1↓, 4,   HDAC10↓, 1,   HDAC10↑, 1,   HDAC2↓, 1,   HDAC3↓, 2,   HDAC8↓, 2,   IRF1↑, 1,   KLF2↓, 1,   KLF5↓, 1,   miR-124-3p↓, 1,   miR-129-5p↑, 1,   miR-133a-3p↑, 1,   miR-139-5p↑, 1,   miR-155↓, 1,   miR-199↓, 1,   miR-200b↑, 1,   miR-200c↑, 1,   miR-203↑, 1,   miR-21↓, 1,   miR-218↑, 1,   miR-22↑, 1,   miR-29b↑, 1,   miR-30a-5p↑, 2,   miR-375↑, 1,   miR-490↑, 1,   Myc↓, 5,   n-MYC↓, 1,   NDRG1↑, 1,   OCT4↓, 10,   other?, 4,   other↓, 8,   other↑, 18,   other↝, 63,   other∅, 2,   PhotoS↑, 3,   SD↑, 1,   SETBP1↓, 1,   sonoS↑, 2,   SOX2↓, 7,   SOX4↑, 1,   SOX9↓, 1,   SUV39H↓, 3,   TCF-4↓, 1,   TFE3↑, 2,   tumCV?, 1,   tumCV↓, 113,   tumCV↑, 3,   tumCV∅, 1,  

Protein Folding & ER Stress(tgid=8) ⓘ

ATF6↑, 2,   CHOP/DDIT3↓, 2,   CHOP/DDIT3↑, 33,   e-CRT↑, 1,   EDEM↑, 1,   eIF2α↓, 1,   eIF2α↑, 6,   p‑eIF2α↓, 1,   p‑eIF2α↑, 8,   ER Stress↓, 2,   ER Stress↑, 80,   ER Stress↝, 1,   ERStress↑, 1,   GRP78/BiP?, 1,   GRP78/BiP↓, 5,   GRP78/BiP↑, 18,   HSF1↓, 1,   HSP27↓, 1,   HSP27↑, 1,   HSP70/HSPA5↓, 6,   HSP70/HSPA5↑, 4,   e-HSP70/HSPA5↑, 1,   HSP90↓, 13,   HSP90↑, 2,   e-HSP90↑, 2,   ac‑HSP90↑, 1,   HSPs↑, 2,   HSPs∅, 1,   IRE1↑, 4,   NPL4↓, 2,   PERK↑, 9,   p‑PERK↓, 1,   p‑PERK↑, 1,   Proteasome↓, 4,   PSMB5↓, 1,   UPR↓, 1,   UPR↑, 14,   mt-UPR↑, 1,   XBP-1↑, 6,   XBP-1↝, 1,  

Autophagy & Lysosomes(tgid=9) ⓘ

APA↑, 1,   ATG3↓, 1,   ATG5↑, 5,   ATG7↑, 1,   Beclin-1/ATG6↓, 2,   Beclin-1/ATG6↑, 14,   p‑Beclin-1/ATG6↑, 1,   LAMP1?, 1,   LC3‑Ⅱ/LC3‑Ⅰ↑, 3,   LC3B↑, 3,   LC3B-II↑, 5,   LC3II↑, 19,   LC3s↑, 2,   lysoMP↓, 1,   lysoMP↑, 1,   MitoP↑, 3,   p62↓, 11,   p62↑, 6,   p‑p62↑, 1,   PARK2↑, 4,   SESN2↑, 3,   TFEB↑, 1,   TumAuto↓, 5,   TumAuto↑, 75,   TumAuto↝, 1,   mt-TumAuto↑, 1,  

DNA Damage & Repair(tgid=10) ⓘ

ATM↓, 1,   ATM↑, 5,   ATR↑, 1,   BRCA1↓, 2,   p‑BRCA1↑, 1,   BRCA2↓, 3,   DNA-PK↑, 2,   DNAdam↓, 5,   DNAdam↑, 97,   mt-DNAdam↑, 1,   DNArepair↓, 3,   hTERT/TERT↓, 7,   MDMX↓, 1,   NKX3.1↓, 2,   p16↑, 3,   P53↓, 6,   P53↑, 72,   P53↝, 3,   P53∅, 1,   p‑P53↑, 6,   p53 Wildtype↓, 1,   PARP↓, 6,   PARP↑, 16,   p‑PARP↑, 1,   cl‑PARP↑, 103,   cl‑PARP∅, 1,   proPARP↓, 1,   cl‑PARP1↑, 4,   PCNA↓, 12,   SIRT6↓, 2,   SIRT6↑, 1,   Telomerase↓, 16,   TOP1↓, 4,   TOP1↑, 1,   TOP1↝, 1,   TOP2↓, 2,   TOP2↑, 2,   TP53↓, 2,   TRF2↓, 1,   UHRF1↓, 1,   γH2AX↑, 12,   p‑γH2AX↑, 5,  

Cell Cycle & Senescence(tgid=11) ⓘ

ANAPC2↑, 1,   AURKB↑, 1,   CDK1?, 1,   CDK1↓, 11,   p‑CDK1↓, 1,   p‑CDK1↑, 1,   CDK2↓, 20,   CDK4↓, 31,   CDK4↑, 3,   p‑CDK4↓, 1,   CDK6↓, 11,   CDK6↑, 5,   CDK8↓, 1,   CDKN2C/p18↑, 1,   cellSen↑, 1,   CHK1↓, 1,   Chk2↑, 2,   Cyc↓, 2,   cycA1/CCNA1↓, 8,   cycA1/CCNA1↑, 2,   CycB/CCNB1↓, 22,   CycB/CCNB1↑, 5,   cycD1/CCND1↓, 56,   cycD1/CCND1↑, 1,   p‑cycD1/CCND1↓, 1,   CycD3↓, 2,   CycD3↑, 1,   cycE/CCNE↓, 13,   cycE/CCNE↑, 1,   cycF↑, 1,   E2Fs↓, 1,   GADD45A↑, 2,   Ki-67↓, 26,   mitA↓, 1,   mitA↑, 1,   p19↑, 1,   P21↓, 3,   P21↑, 57,   p27/CDKN1B↑, 22,   PLK1↓, 1,   RB1↑, 2,   p‑RB1↓, 4,   TubPol↓, 1,   TumCCA?, 1,   TumCCA↓, 6,   TumCCA↑, 228,   UBE2C↓, 1,  

Proliferation, Differentiation & Cell State(tgid=12) ⓘ

ALDH↓, 9,   ALDH1A1↓, 4,   BMI1↓, 3,   CD133↓, 9,   CD24↓, 3,   CD34↓, 1,   cFos↓, 2,   cFos↑, 1,   cMYB↓, 1,   CSCs↓, 48,   CSCs↑, 2,   CSCsMark↓, 1,   Diff↓, 1,   Diff↑, 4,   FGF↓, 2,   Gli↓, 1,   Gli1↓, 6,   HH↓, 8,   HMGCR↓, 1,   IGF-1?, 1,   IGF-1↓, 18,   IGF-1↑, 1,   IGF-1↝, 1,   IGF-1∅, 1,   IGF-2↓, 1,   IGFBP1↓, 1,   IGFBP1↑, 3,   IGFBP3↑, 3,   Ki-67↓, 26,   Let-7↑, 1,   mTORC1↓, 4,   p‑mTORC1↓, 1,   Nanog↓, 10,   Nestin↓, 1,   NOTCH↓, 4,   NOTCH↑, 1,   NOTCH1↓, 5,   NOTCH1↑, 1,   NOTCH3↓, 1,   p300↓, 1,   Piezo1↑, 1,   PTCH1↓, 2,   Shh↓, 4,   Smo↓, 4,   STAT1↓, 1,   TumCG?, 1,   TumCG↓, 161,   TumCG↑, 5,   TumCG↝, 2,   TumCG∅, 1,   TumCP↓, 211,   TumCP↑, 7,   TumCP∅, 3,   Wnt?, 1,   Wnt↓, 27,   Wnt/(β-catenin)↓, 2,  

Migration(tgid=13) ⓘ

Alix/AIP‑1↓, 1,   AntiAg↑, 4,   AP-1↓, 7,   ATPase↓, 1,   ATPase↑, 1,   AXL↓, 3,   BACH1↑, 1,   CA↓, 1,   Ca+2↓, 8,   Ca+2↑, 45,   Ca+2↝, 5,   i-Ca+2?, 1,   i-Ca+2↓, 1,   i-Ca+2↑, 3,   CAFs/TAFs↓, 2,   Cdc42↓, 2,   Cdc42↑, 1,   Chl↑, 1,   Chl∅, 1,   CTNNB1↓, 1,   E-cadherin↓, 3,   E-cadherin↑, 25,   EMT↓, 44,   EMT↑, 1,   EpCAM↓, 1,   F-actin↓, 1,   FAK↓, 10,   p‑FAK↓, 2,   p‑FAK↑, 1,   FOSB↑, 1,   GLI2↓, 3,   hnRNPA1↓, 1,   ITGA1∅, 1,   ITGA5∅, 1,   ITGB1↓, 1,   ITGB1∅, 1,   ITGB3↓, 1,   ITGB3∅, 1,   ITGB4∅, 1,   KRAS↓, 2,   LEF1↓, 2,   LRP1↓, 1,   MALAT1↓, 1,   MET↓, 2,   p‑MET↓, 1,   MMP1↓, 6,   MMP13↓, 1,   MMP2↓, 52,   MMP2↑, 1,   MMP2∅, 1,   proMMP2↓, 1,   MMP3↓, 3,   MMP7↓, 4,   MMP9↓, 60,   MMP9↑, 2,   MMP9∅, 1,   MMPs↓, 20,   MTA1↓, 1,   MUC1↑, 1,   N-cadherin↓, 9,   N-cadherin↑, 1,   NEDD9↓, 1,   p‑p44↓, 1,   PAK1↓, 3,   PAK1↑, 1,   PDGF↓, 3,   Rac1↓, 1,   Rho↓, 5,   ROCK1↓, 2,   Slug↓, 4,   Smad1↓, 1,   SMAD3↓, 2,   Snail?, 1,   Snail↓, 16,   SPARC↑, 1,   TET1?, 1,   TET1↑, 2,   TGF-β↓, 5,   TGF-β1↓, 2,   TIMP1↓, 1,   TIMP1↑, 2,   TIMP2↓, 1,   TIMP2↑, 6,   TRIB3↑, 1,   TSC1↑, 1,   TSP-1↑, 2,   TumCA↓, 2,   TumCI?, 1,   TumCI↓, 62,   TumCI↑, 1,   TumCMig↓, 66,   TumCMig↑, 2,   TumMeta↓, 62,   TumMeta↑, 5,   TumPF↓, 1,   Twist↓, 10,   TXNIP↑, 1,   Tyro3↓, 1,   uPA↓, 9,   uPAR↓, 2,   Vim↓, 16,   Vim↑, 1,   Zeb1↓, 8,   ZEB2↓, 1,   α-tubulin↓, 1,   β-catenin/ZEB1↓, 39,   β-catenin/ZEB1↑, 1,  

Angiogenesis & Vasculature(tgid=14) ⓘ

angioG↓, 91,   angioG↑, 4,   angioG∅, 1,   CD31/PECAM-1↓, 1,   EGR1↑, 1,   Endoglin↑, 1,   eNOS↑, 1,   HIF-1↓, 1,   Hif1a↓, 48,   Hif1a↑, 3,   Hypoxia↓, 1,   LOX1↓, 1,   NO↓, 1,   NO↑, 8,   PHDs↓, 1,   VCAM-1↓, 2,   VEGF↓, 65,   VEGFR1↓, 3,   VEGFR2/KDR/Flk1↓, 5,  

Barriers & Transport(tgid=15) ⓘ

AQPs↓, 2,   BBB↑, 9,   BBB∅, 1,   CellMemb↓, 1,   CellMemb↑, 6,   CLDN1↓, 2,   CLDN1↑, 1,   CLDN2↓, 1,   CLDN2↑, 1,   CTR1↑, 1,   EPR↓, 1,   EPR↑, 19,   EPR↝, 1,   GLUT1↓, 15,   GLUT1↑, 1,   GLUT2↓, 1,   GLUT3↓, 2,   GLUT4↓, 3,   IBI↑, 2,   KCNH2/hERG↓, 1,   LAT↓, 1,   MMP?, 1,   MMP↓, 198,   MMP↑, 1,   MPT↑, 11,   NHE1↓, 2,   OATPs↓, 1,   OCLN↑, 1,   SLC12A5↓, 2,   SMCT1∅, 1,   sonoP↑, 2,   TJ↓, 1,   TJ↑, 1,   TRPM7↓, 2,   TRPV1↑, 5,   VGCC↑, 1,   VGSC↑, 1,   ZO-1↑, 4,  

Immune & Inflammatory Signaling(tgid=16) ⓘ

CCR7↓, 1,   CD14↓, 1,   CD4+↓, 1,   CD4+↑, 2,   CD44↓, 12,   CD47↓, 1,   CD8+↑, 9,   cDC2↓, 4,   cGAS–STING↑, 1,   COX1↓, 4,   COX2/PTGS2↓, 48,   COX2/PTGS2↑, 5,   CR3↝, 1,   CXCR2↓, 1,   CXCR4↓, 11,   DCells↑, 1,   Dectin1↝, 1,   DR4↑, 6,   DR4∅, 1,   DR6↑, 1,   Eos↑, 1,   Gal1↑, 1,   HCAR2↑, 1,   HMGB1↓, 2,   e-HMGB1↑, 1,   ICAM-1↓, 3,   IFN-γ↓, 1,   IFN-γ↑, 5,   Igs↑, 2,   IL-1Ra↑, 1,   IL1↓, 3,   IL1↑, 2,   IL10↓, 3,   IL10↑, 2,   IL12↓, 1,   IL12↑, 1,   IL17↑, 1,   IL18↑, 1,   IL1R2↑, 1,   IL1RL1/ST2↑, 1,   IL1α↓, 1,   IL1β↓, 12,   IL1β↑, 1,   IL2↓, 2,   IL2↑, 6,   IL4↓, 3,   IL6↓, 25,   IL6↑, 1,   IL7↓, 1,   IL8↓, 6,   IL8↑, 1,   Imm↑, 36,   Imm↝, 3,   Inflam↓, 33,   Inflam↑, 1,   IRAK4↓, 1,   pol-M1↑, 1,   pol-M1↝, 1,   M2 MC↓, 3,   pol-M2 MC↓, 1,   MCP1/CCL2↓, 3,   MIP2↓, 1,   Neut↓, 1,   NF-kB↓, 105,   NF-kB↑, 5,   p‑NF-kB↓, 1,   p‑NF-kB↑, 1,   NK cell↑, 15,   NLRP3↓, 2,   NLRP3↑, 3,   p50↓, 1,   p65↓, 7,   p‑p65↓, 1,   PD-1↓, 1,   PD-L1↓, 12,   PD-L1↑, 4,   PDT+↓, 1,   PGE2↓, 13,   PSA↓, 13,   RANTES↓, 1,   SOCS1↑, 1,   T-Cell↑, 2,   T-Cell↝, 1,   TCF↓, 3,   TCF↝, 1,   TLR1↑, 1,   TLR2↓, 1,   TLR4↓, 5,   TNF-α↓, 19,   TNF-α↑, 2,   TNFRSF25/DR3/APO3/LARD/TRAMP/WSL1↑, 1,   TRAF1↓, 1,  

Cellular Microenvironment(tgid=17) ⓘ

ADAM17↓, 1,   GFAP↓, 1,   pH↑, 7,   pH↝, 2,   pH∅, 1,   e-pH↓, 1,   e-pH↑, 6,   i-pH↓, 1,   TAMS↑, 1,   Temp↓, 1,  

Synaptic & Neurotransmission(tgid=18) ⓘ

5HT↓, 2,  

Hormonal & Nuclear Receptors(tgid=20) ⓘ

6IL↑, 1,   ACTH↓, 1,   AR↓, 19,   AR↑, 1,   AR↝, 1,   AR-FL↓, 1,   AR-V7↑, 1,   CYP11A1↓, 1,   CYP19↓, 1,   CYP24A1↓, 1,   ER-α36↓, 1,   ER(estro)↓, 2,   Estro↝, 1,   FKBP5↓, 1,   GR↓, 1,   Leptin↓, 1,   PPARα↓, 1,   PPARγ↓, 1,   PPARγ↑, 3,   RANKL↓, 1,   SRC3↓, 1,   SXR↑, 1,   VDR↑, 1,  

Drug Metabolism & Resistance(tgid=21) ⓘ

ABCC2↓, 1,   BioAv↓, 49,   BioAv↑, 64,   BioAv↝, 12,   BioAv∅, 1,   BioEnh?, 1,   BioEnh↑, 10,   CBR1↓, 1,   chemoR↓, 2,   ChemoSen?, 1,   ChemoSen↓, 6,   ChemoSen↑, 209,   ChemoSen↝, 1,   CompStab↓, 3,   CompStab↑, 4,   CompStab↝, 1,   CYP1A1↓, 2,   CYP1A1↑, 1,   DDS↑, 10,   Dose?, 16,   Dose↓, 8,   Dose↑, 22,   Dose⇅, 1,   Dose↝, 153,   Dose∅, 29,   DrugR↓, 1,   eff?, 5,   eff↓, 440,   eff↑, 818,   eff⇅, 4,   eff↝, 143,   eff∅, 26,   GSTA1↓, 2,   GSTZ1↓, 1,   GSTZ1↝, 1,   GSTZ1∅, 1,   Half-Life↓, 16,   Half-Life↑, 9,   Half-Life↝, 13,   Half-Life∅, 2,   MDR1↓, 6,   MRP↓, 2,   MRP1/ABCC1↓, 1,   P-gp/ABCB1↓, 21,   P-gp/ABCB1∅, 1,   P450↓, 2,   RadioS↓, 1,   RadioS↑, 81,   RadioS↝, 1,   RadioS∅, 1,   selectivity?, 2,   selectivity↓, 3,   selectivity↑, 199,   selectivity↝, 1,   selectivity∅, 2,   Synergy↑, 132,   Synergy∅, 1,   TET2↑, 3,  

Clinical Biomarkers(tgid=22) ⓘ

AFP?, 1,   AFP↓, 3,   ALAT↓, 2,   ALAT∅, 1,   ALB∅, 1,   ALP↓, 2,   AR↓, 19,   AR↑, 1,   AR↝, 1,   ascitic↓, 1,   AST↓, 2,   AST∅, 1,   BG↓, 6,   BMD↑, 2,   BP↓, 1,   BRAF↓, 1,   BRCA1↓, 2,   p‑BRCA1↑, 1,   CA125↓, 1,   CA125∅, 1,   CA19-9↓, 1,   CEA↓, 3,   CRP↓, 2,   CRP∅, 1,   E6↓, 1,   E7↓, 1,   EGFR↓, 24,   EGFR↑, 2,   p‑EGFR↓, 1,   EZH2↓, 1,   Ferritin↓, 5,   Ferritin↑, 1,   Hcy/homoC↓, 4,   Hcy/homoC↝, 1,   HER2/EBBR2↓, 8,   HOMA↓, 1,   hTERT/TERT↓, 7,   IL6↓, 25,   IL6↑, 1,   KeyT↑, 1,   KRAS↓, 2,   LDH?, 1,   LDH↓, 8,   LDH↑, 4,   LDH↝, 1,   i-LDH↓, 1,   Myc↓, 5,   NOS2↑, 1,   NSE↓, 1,   PD-L1↓, 12,   PD-L1↑, 4,   PSA↓, 13,   TP53↓, 2,   TRIB3↑, 1,  

Functional Outcomes(tgid=23) ⓘ

AntiAge↑, 2,   AntiCan↓, 3,   AntiCan↑, 80,   AntiCan∅, 1,   AntiDiabetic↑, 1,   antiNeop↑, 4,   AntiTum↓, 3,   AntiTum↑, 34,   AntiTum⇅, 1,   cachexia↓, 2,   cardioP↑, 11,   CardioT↓, 1,   CardioT↑, 2,   CardioT↝, 1,   chemoP↑, 40,   chemoP↝, 1,   chemoPv↑, 19,   ChemoSideEff↓, 15,   cognitive↑, 5,   fatigue↓, 3,   hepatoP↓, 1,   hepatoP↑, 8,   memory↑, 2,   motorD↑, 1,   Mucositis↓, 1,   MusCon↓, 2,   neuroP↑, 7,   NKG2D↑, 1,   NP/CIPN↓, 1,   NP/CIPN↑, 2,   OS?, 2,   OS↑, 65,   OS↝, 1,   OS∅, 1,   PARP16↓, 1,   PFS?, 1,   PFS↑, 3,   QoL↑, 12,   QoL∅, 3,   radioP↑, 20,   radioP↝, 1,   Remission↑, 4,   RenoP↑, 4,   Risk↓, 35,   Risk↑, 1,   Risk∅, 4,   Sleep↑, 1,   Strength∅, 1,   toxicity↓, 51,   toxicity↑, 8,   toxicity⇅, 1,   toxicity↝, 25,   toxicity∅, 8,   TumVol↓, 58,   TumW↓, 29,   Weight↓, 1,   Weight↑, 7,   Weight∅, 5,   Wound Healing↑, 2,  

Infection & Microbiome(tgid=24) ⓘ

AntiP↑, 2,   Bacteria↓, 4,   Dectin1↝, 1,   GutMicro↑, 13,   GutMicro↝, 3,   Sepsis↓, 1,  

Ingredients & Constituents(tgid=25) ⓘ

Ingr↝, 4,  
Total Targets: 1245

Pathway results for Effect on Normal Cells:


NA, unassigned(tgid=0) ⓘ

NA↑, 1,  

Redox & Oxidative Stress(tgid=1) ⓘ

antiOx?, 1,   antiOx↓, 10,   antiOx↑, 99,   mt-antiOx↑, 1,   ARE↑, 2,   Bil↓, 1,   Catalase↓, 1,   Catalase↑, 37,   Copper↓, 1,   CoQ10↑, 1,   DPPH↓, 1,   Fenton↓, 3,   GPx↑, 26,   GPx1↑, 1,   GPx4↓, 1,   GPx4↑, 3,   GPx4∅, 1,   GSH↓, 3,   GSH↑, 48,   GSR↑, 4,   GSTs↑, 8,   H2O2↓, 5,   H2O2↑, 1,   HDL↓, 1,   HDL↑, 5,   HDL∅, 2,   HO-1?, 1,   HO-1↓, 1,   HO-1↑, 28,   HO-1↝, 1,   HO-1∅, 1,   hyperG↓, 1,   Iron↓, 3,   Keap1↓, 2,   Keap1↑, 1,   lipid-P↓, 33,   lipid-P↑, 1,   mt-lipid-P↓, 1,   MDA↓, 30,   MDA↑, 1,   MDA∅, 1,   MPO↓, 5,   MPO↑, 1,   NADH↓, 1,   NOX↓, 1,   NOX4↓, 1,   NQO1↑, 7,   Nrf1↑, 1,   NRF2↓, 4,   NRF2↑, 51,   NRF2⇅, 1,   NRF2∅, 1,   Prx↑, 1,   RNS↓, 5,   ROS?, 4,   ROS↓, 132,   ROS↑, 14,   ROS⇅, 3,   ROS↝, 1,   ROS∅, 7,   mt-ROS↓, 1,   mt-ROS↑, 2,   selenoP↑, 4,   SOD↓, 3,   SOD↑, 59,   SOD1↑, 2,   TAC↑, 7,   TBARS↓, 4,   Trx↑, 2,   TrxR↑, 1,   uricA↓, 3,   VitC↑, 4,   VitE↓, 1,   VitE↑, 1,   xCT/SLC7A11↑, 1,  

Metal & Cofactor Biology(tgid=2) ⓘ

Ferritin↓, 1,   FPN↑, 1,   IronCh↑, 6,   IronCh↝, 1,   Mets↝, 1,   NCOA4↝, 1,   TfR1/CD71↑, 1,  

Mitochondria & Bioenergetics(tgid=3) ⓘ

compI↓, 1,   compII↑, 1,   compIII↓, 1,   compIII↑, 1,   DRP1/DNM1L↑, 1,   ETC↓, 1,   ETC↑, 1,   FIS1↓, 1,   FIS1↑, 1,   Insulin↓, 3,   Insulin↑, 1,   mitResp↑, 2,   mtDam↓, 6,   OCR↑, 1,   mt-OCR↑, 1,   OXPHOS↑, 1,   PGC-1α↑, 4,  

Core Metabolism/Glycolysis(tgid=4) ⓘ

12-HETE↓, 1,   12LOX↓, 3,   5-HETE↓, 1,   5LO↓, 3,   ACSL4∅, 1,   adiP↓, 1,   adiP↑, 2,   ALAT↓, 15,   ALAT∅, 1,   AMPK↓, 1,   AMPK↑, 6,   ATP↓, 3,   ATP↑, 9,   BHB↑, 1,   cAMP↑, 2,   DHA↑, 1,   ECAR↓, 1,   ECAR↑, 1,   Eic↓, 1,   mt-FAO↑, 1,   glucose↓, 4,   glucose↑, 1,   GlucoseCon↑, 4,   Glycolysis↓, 1,   GSK‐3β↓, 4,   GSK‐3β↑, 1,   GSK‐3β↝, 1,   p‑GSK‐3β↑, 1,   KeyT↑, 4,   lactateProd↓, 1,   LDL↓, 14,   lipidLev↓, 1,   NAD↑, 1,   NADH:NAD↑, 1,   NADPH↓, 2,   NADPH↑, 3,   PKM2↓, 2,   SCD1↓, 1,   SIRT1↓, 1,   SIRT1↑, 8,   SIRT2↑, 1,  

Cell Death(tgid=5) ⓘ

Apoptosis↓, 15,   Apoptosis∅, 2,   ASK1↓, 1,   BAX↓, 6,   BAX↑, 2,   Bax:Bcl2↓, 2,   Bcl-2↓, 2,   Bcl-2↑, 3,   Bcl-2∅, 1,   Bcl-xL↓, 1,   Bcl-xL↑, 1,   Casp12↓, 2,   Casp3↓, 16,   Casp3↑, 2,   Casp3∅, 1,   cl‑Casp3↓, 2,   cl‑Casp8↑, 1,   Casp9↓, 6,   Casp9↑, 1,   Cyt‑c↓, 5,   Cyt‑c↑, 3,   Cyt‑c∅, 3,   Ferroptosis↓, 4,   GranB/GZMB↓, 1,   HEY1↑, 1,   iNOS↓, 13,   iNOS↑, 1,   necrosis↓, 1,   p38↓, 1,   p38↑, 2,   p‑p38↓, 1,   TUNEL↓, 1,  

Kinase & Signal Transduction(tgid=6) ⓘ

Akt↓, 4,   Akt↑, 7,   e-Akt↑, 1,   AKT1↓, 1,   Akt2↓, 1,   AMPKα↑, 1,   CREB↑, 1,   ERK↓, 1,   ERK↑, 4,   e-ERK↑, 1,   HCAR2↑, 1,   IKKα↓, 1,   IκB?, 1,   JAK2↑, 1,   JNK↓, 4,   JNK↑, 1,   p‑JNK↓, 1,   MAPK↓, 7,   MAPK↑, 6,   Mst1↓, 1,   mTOR↓, 5,   mTOR↑, 1,   mTOR↝, 1,   p‑mTOR↓, 1,   p‑mTOR↑, 1,   PI3K↓, 4,   PI3K↑, 4,   PKA↑, 2,   PKCδ?, 1,   PKCδ↓, 1,   PKCδ↑, 1,   PP2A↑, 1,   PTEN↓, 2,   RAS↓, 1,   STAT↓, 1,   STAT3↓, 3,   STAT3↑, 1,  

Transcription & Epigenetics(tgid=7) ⓘ

AntiThr↑, 4,   ATF4↓, 1,   FOXO↑, 1,   HDAC↓, 1,   other?, 4,   other↓, 9,   other↑, 27,   other↝, 44,   SOX9↑, 1,   tumCV↓, 1,   tumCV∅, 1,  

Protein Folding & ER Stress(tgid=8) ⓘ

CHOP/DDIT3↓, 2,   CHOP/DDIT3↑, 1,   p‑eIF2α↓, 1,   cl‑eIF2α↑, 1,   ER Stress↓, 6,   ER Stress↑, 1,   GRP78/BiP↓, 4,   GRP78/BiP↑, 1,   HSF1↑, 2,   HSP70/HSPA5↓, 1,   HSP70/HSPA5↑, 2,   HSP70/HSPA5↝, 1,   HSPs↑, 3,   IRE1↓, 2,   p‑PERK↑, 1,   UPR↓, 1,   XBP-1↓, 1,  

Autophagy & Lysosomes(tgid=9) ⓘ

CTSZ↓, 1,   LC3‑Ⅱ/LC3‑Ⅰ↑, 1,   LC3II↑, 1,   MitoP↑, 1,   p62↑, 1,  

DNA Damage & Repair(tgid=10) ⓘ

DNAdam↓, 13,   DNAdam↑, 2,   DNArepair↑, 3,   P53↑, 2,   PARP↓, 1,   γH2AX↓, 1,   p‑γH2AX↓, 1,  

Cell Cycle & Senescence(tgid=11) ⓘ

cycD1/CCND1↓, 1,   E2Fs↑, 1,   P21↑, 1,   TumCCA↑, 1,  

Proliferation, Differentiation & Cell State(tgid=12) ⓘ

BMP2↑, 1,   Choline↑, 1,   Diff↑, 4,   Diff↝, 1,   FGF↑, 1,   IGF-1↓, 2,   IGFBP3↑, 1,   neuroG↑, 1,   NOTCH↑, 1,   TumCP↓, 2,   tyrosinase↓, 1,   Wnt↑, 2,  

Migration(tgid=13) ⓘ

AntiAg↓, 1,   AntiAg↑, 10,   ARG1/2↑, 1,   Ca+2↓, 3,   Ca+2↑, 7,   Ca+2↝, 4,   cal2↓, 1,   Cartilage↑, 1,   COL1↓, 1,   COL2A1↑, 1,   E-cadherin↑, 1,   EMT↓, 2,   EMT↑, 1,   F-actin↑, 1,   FAK↑, 2,   MLC2/MYL9↝, 1,   MMP13↓, 1,   MMP2↓, 2,   MMP2↑, 2,   MMP9↓, 11,   MMP9↑, 2,   MMPs↓, 1,   MMPs↑, 1,   PAI-1/SERPINE1↓, 1,   SMAD3↓, 2,   Snail↑, 1,   TG2/TGase↓, 1,   TGF-β↓, 1,   TGF-β↑, 4,   TGF-β1↓, 1,   TIMP1↓, 2,   TIMP1↑, 1,   TumCI↓, 1,   TumCMig↓, 1,   Twist↑, 1,   Vim↓, 1,   Vim↑, 1,   α-SMA↓, 1,   β-catenin/ZEB1↑, 2,  

Angiogenesis & Vasculature(tgid=14) ⓘ

angioG↓, 1,   angioG↑, 2,   CD31/PECAM-1↑, 1,   eNOS↑, 1,   Hif1a↓, 2,   Hif1a↑, 2,   Hif1a∅, 1,   NO?, 1,   NO↓, 13,   NO↑, 4,   VCAM-1↓, 2,   VEGF↓, 2,   VEGF↑, 5,  

Barriers & Transport(tgid=15) ⓘ

BBB↓, 1,   BBB↑, 37,   BBB↝, 1,   BBB∅, 2,   CellMemb↑, 1,   CLDN1↓, 1,   CLDN1↑, 1,   CLDN1↝, 1,   EPR↑, 1,   GastroP↑, 5,   GLUT1↑, 2,   GLUT3↑, 1,   GLUT4↑, 1,   IBI↑, 1,   ketosis↑, 1,   MMP↓, 4,   MMP↑, 10,   MMP↝, 1,   MMP∅, 2,   MPT↑, 1,   OCLN↝, 1,   TJ↓, 1,   TJ↑, 2,   TRPV3↑, 1,   VGCC↑, 2,   VGCC⇅, 1,   VGSC↓, 1,   ZO-1↓, 1,   ZO-1↑, 1,   ZO-1↝, 1,  

Immune & Inflammatory Signaling(tgid=16) ⓘ

CD14↑, 1,   CD25+↑, 1,   CD4+↑, 3,   CD8+↑, 2,   COX1↓, 2,   COX2/PTGS2↓, 22,   CXCR4↓, 1,   Eos↓, 1,   FOXP3↑, 1,   HCAR2↑, 1,   HMGB1↓, 2,   IFN-γ↓, 3,   IFN-γ↑, 2,   IgE↓, 1,   IL1↓, 2,   IL10?, 1,   IL10↓, 2,   IL10↑, 9,   IL10∅, 1,   IL17↓, 7,   IL17∅, 1,   IL18↓, 1,   IL1α↓, 1,   IL1β↓, 26,   IL2↓, 2,   IL22↓, 1,   IL23↓, 1,   IL4↓, 1,   IL4↑, 3,   IL4∅, 1,   IL5↑, 1,   IL6↓, 33,   IL6↑, 4,   IL8↓, 3,   Imm↑, 18,   Imm⇅, 1,   INF-γ↓, 1,   Inflam?, 1,   Inflam↓, 130,   Inflam↑, 2,   IRF3↓, 1,   LPS↓, 2,   M2 MC↑, 1,   MCP1/CCL2↓, 4,   MCP1/CCL2↑, 1,   MIP‑1α/CCL3↓, 1,   MyD88↓, 2,   NeuroI↓, 1,   NF-kB↓, 31,   NF-kB↑, 2,   NK cell↑, 1,   NLRP3↓, 5,   NLRP3↑, 1,   p65↓, 1,   PAF↓, 1,   PGE2↓, 9,   PSA↓, 1,   TLR1↓, 1,   TLR2↓, 2,   TLR4↓, 4,   TNF-α↓, 48,   TNF-α↑, 1,   Treg lymp↑, 1,   Treg lymp↝, 1,  

Cellular Microenvironment(tgid=17) ⓘ

pH↝, 1,   Temp↝, 1,  

Synaptic & Neurotransmission(tgid=18) ⓘ

5-AR↓, 1,   5HT↓, 1,   5HT↑, 2,   Ach?, 1,   Ach↑, 6,   AChE↓, 24,   AChE∅, 2,   ADAM10↑, 1,   BChE↓, 9,   BDNF↑, 15,   BrainVol↑, 1,   BrainVol∅, 1,   ChAT↑, 1,   GABA↑, 3,   MAOA↓, 2,   NMDAR↑, 1,   PSD95↑, 1,   SNAP25↑, 1,   TrkB↑, 1,   β-Endo↑, 1,  

Protein Aggregation(tgid=19) ⓘ

AGEs↓, 3,   APP↓, 4,   Aβ↓, 32,   Aβ42↓, 1,   BACE/β-secretase↓, 8,   IDE↑, 1,   tau↓, 4,   p‑tau↓, 8,   XO↝, 1,   β-Amyloid↓, 1,  

Hormonal & Nuclear Receptors(tgid=20) ⓘ

BNP↓, 1,   GPER↑, 1,   GR↑, 2,   PPARα↑, 1,   PPARγ↓, 1,   PPARγ↑, 3,  

Drug Metabolism & Resistance(tgid=21) ⓘ

BioAv?, 1,   BioAv↓, 36,   BioAv↑, 66,   BioAv⇅, 1,   BioAv↝, 24,   BioEnh↑, 8,   ChemoSen↑, 1,   CompStab↓, 1,   CompStab↑, 5,   CompStab↝, 2,   CYP1A1↓, 1,   CYP2C19↓, 1,   CYP2C8↓, 1,   CYP2C9↓, 1,   CYP2D6↓, 1,   CYP2E1↓, 1,   CYP3A4↓, 2,   DDS↑, 1,   Dose?, 2,   Dose↓, 8,   Dose↑, 7,   Dose⇅, 1,   Dose↝, 93,   Dose∅, 2,   eff?, 2,   eff↓, 37,   eff↑, 262,   eff↝, 36,   eff∅, 2,   GSTA1↓, 2,   GSTA1↑, 1,   Half-Life↓, 5,   Half-Life↑, 7,   Half-Life⇅, 1,   Half-Life↝, 14,   Half-Life∅, 3,   P-gp/ABCB1↓, 3,   P450↓, 1,   selectivity↑, 2,   Synergy↑, 13,  

Clinical Biomarkers(tgid=22) ⓘ

ALAT↓, 15,   ALAT∅, 1,   ALP↓, 4,   ALP↑, 1,   anemia↓, 1,   AST↓, 15,   AST∅, 1,   BG↓, 1,   Bil↓, 1,   BloodF↑, 3,   BMD↑, 7,   BP↓, 16,   BP∅, 1,   BUN↓, 3,   creat↓, 6,   CRP↓, 7,   Ferritin↓, 1,   FEV1↑, 2,   Hcy/homoC↓, 2,   HemoG↑, 1,   hs-CRP↓, 1,   IL6↓, 33,   IL6↑, 4,   KeyT↑, 4,   LDH↓, 6,   LDH↑, 1,   LDH∅, 1,   NLR↓, 1,   NOS2↓, 2,   PEF↑, 1,   PSA↓, 1,   PV↓, 1,   RBC↑, 1,   SpO2↑, 1,   TC↓, 1,   TMAO↑, 3,   TMAO⇅, 1,   UFR?, 1,   UFR↑, 1,   UR↓, 1,   Urea↓, 1,  

Functional Outcomes(tgid=23) ⓘ

Analgesic↑, 1,   AntiAge↑, 5,   antiAll↑, 15,   antiAll∅, 1,   AntiArt↑, 7,   AntiCan↑, 11,   antiD↓, 1,   AntiDiabetic↑, 18,   antiPs↑, 1,   AntiTum↓, 1,   AntiTum↑, 3,   BOLD↑, 2,   Bone Healing↑, 1,   cachexia↓, 1,   cardioP↑, 36,   CardioT↓, 3,   chemoP↑, 10,   chemoPv↑, 5,   cognitive?, 1,   cognitive↓, 3,   cognitive↑, 71,   cognitive∅, 1,   diuretic↑, 1,   fatigue↓, 1,   hepatoP↓, 1,   hepatoP↑, 31,   IPSS↝, 1,   Learn↑, 1,   memory↓, 2,   memory↑, 41,   memory∅, 1,   Mood?, 1,   Mood↑, 5,   motorD↓, 1,   motorD↑, 13,   MusCon↓, 1,   Nausea↓, 1,   neuroP?, 1,   neuroP↑, 73,   Obesity↓, 8,   OS↓, 1,   OS↑, 5,   Pain↓, 9,   PDE4↓, 1,   QoL↑, 1,   radioP↑, 4,   RenoP↑, 15,   Risk↓, 8,   Risk↑, 2,   Sleep↑, 5,   Strength↑, 2,   Stress↓, 3,   Stroke↓, 8,   toxicity?, 3,   toxicity↓, 78,   toxicity↑, 7,   toxicity↝, 11,   toxicity∅, 26,   Vomit↓, 1,   Weight↓, 4,   Weight↑, 1,   Weight↝, 1,   Weight∅, 1,   Wound Healing↓, 1,   Wound Healing↑, 11,  

Infection & Microbiome(tgid=24) ⓘ

AntiBio↑, 7,   AntiFungal↑, 4,   AntiP↓, 1,   AntiP↑, 2,   AntiViral↑, 13,   Bacteria↓, 26,   Diar↓, 1,   Dysb↓, 1,   GutMicro↑, 15,   GutMicro↝, 1,   Inf↓, 1,   Sepsis↓, 7,  

Ingredients & Constituents(tgid=25) ⓘ

Ingr↑, 2,   Ingr↝, 5,   Phen↑, 1,  
Total Targets: 611

Scientific Paper Hit Count for: eff, efficacy
64 Silver-NanoParticles
59 Magnetic Fields
33 Sulforaphane (mainly Broccoli)
28 Thymoquinone
27 Curcumin
26 immunotherapy
26 Shikonin
25 Chemotherapy
25 Vitamin C (Ascorbic Acid)
23 chitosan
22 Selenite (Sodium)
21 Radiotherapy/Radiation
21 Baicalein
21 Selenium NanoParticles
20 Piperlongumine
19 Copper and Cu NanoParticles
19 EGCG (Epigallocatechin Gallate)
18 Artemisinin
17 Magnetic Field Rotating
16 Melatonin
16 Berberine
16 Exercise
15 Chlorogenic acid
14 Apigenin (mainly Parsley)
14 Luteolin
14 Phenylbutyrate
14 Caffeic acid
14 Capsaicin
14 Resveratrol
14 Quercetin
14 Gambogic Acid
13 Selenium
13 diet FMD Fasting Mimicking Diet
12 Gold NanoParticles
12 Citric Acid
12 Ashwagandha(Withaferin A)
12 Propolis -bee glue
12 Folic Acid, Vit B9
12 Dichloroacetate
12 Hydrogen Gas
11 3-bromopyruvate
11 Cisplatin
11 Betulinic acid
11 Ivermectin
11 Lycopene
11 Phenethyl isothiocyanate
10 Vitamin D3
10 Choline
10 diet Methionine-Restricted Diet
10 Disulfiram
10 Honokiol
9 Auranofin
9 Metformin
9 borneol
9 Electrical Pulses
9 Formononetin
9 Bicarbonate(Sodium)
8 Photodynamic Therapy
8 Fenbendazole
8 SonoDynamic Therapy UltraSound
8 chaetocin
8 doxorubicin
8 Fisetin
8 Hyperthermia
8 Plumbagin
8 Rosmarinic acid
7 Coenzyme Q10
7 Docetaxel
7 Boron
7 buckwheat sprouts
7 Ellagic acid
7 Chrysin
7 Dandelion Root
7 Juglone
7 VitK3,menadione
7 mebendazole
7 salinomycin
6 Alpha-Lipoic-Acid
6 beta-glucans
6 isoorientin
6 Carnosic acid
6 Celastrol
6 Vitamin B12
6 Chlorophyllin
6 Docosahexaenoic Acid
6 Eugenol
6 MCT oil
6 Flaxseed/Linseed
6 Ginger/6-Shogaol/Gingerol
6 isoquercitrin
6 MCT, metronomic chemo
6 Parthenolide
6 Vitamin K2
5 Astragalus
5 Akkermansia
5 Bevacizumab (brand Avastin)
5 Ascorbyl Palmitate
5 Lutein
5 Bifidobacterium
5 Boswellia (frankincense)
5 Piperine
5 Silymarin (Milk Thistle) silibinin
5 Cynaropicrin
5 Diclofenac
5 eicosapentaenoic acid
5 diet Plant based
5 Lemongrass Extract/Citral
5 Ginkgo biloba-EGb 761
5 Gossypol/AT-101
5 Isoliquiritigenin
5 Licochalcone A
5 Moringa oleifera
5 Nimbolide
5 Spermidine
5 Urolithin
4 chemodynamic therapy
4 EMF
4 Cynara scolymus/Globe Artichoke/Artichoke Extract
4 Allicin (mainly Garlic)
4 almonertinib
4 Berbamine
4 α-Bisabolol / Chamomile oil
4 Butyrate
4 capecitabine
4 Carvacrol
4 Cat’s Claw
4 Centella asiatica / Gotu kola → asiaticoside
4 CUSP9
4 diet Short Term Fasting
4 Echinacea
4 Kaempferol
4 phytic acid, Inositol hexakisphosphate
4 Fucoidan
4 Ginkgolide B
4 Ginseng
4 HydroxyCitric Acid
4 Magnolol
4 Isobavachalcone
4 Matrine
4 methylseleninic acid
4 Methylsulfonylmethane
4 Propyl gallate
4 Pterostilbene
4 Terpinen-4-ol / Tea Tree Oil
4 Whole Body Vibration
3 cetuximab
3 5-fluorouracil
3 Anthocyanins
3 Aspirin
3 Atorvastatin
3 Aloe anthraquinones
3 bempedoic acid
3 beta-carotene(VitA)
3 Zeaxanthin
3 Bortezomib
3 Bullatacin
3 NTP, Non-Thermal Plasma,Cold Atmospheric Plasma
3 Thymol-Thymus vulgaris
3 Cannabidiol
3 Chocolate
3 Cichoric acid / Chicoric acid
3 Crocetin
3 Cysteamine
3 erastin
3 Gallic acid
3 Gamma-aminobutyric acid
3 Ginkgo biloba
3 Lemon Balm/Melissa officinalis
3 Germanium Organic/Ge-132 / propagermanium (organogermanium)
3 Gemcitabine (Gemzar)
3 Hibiscus sabdariffa
3 HydroxyTyrosol
3 iodine
3 Inulin Prebiotic
3 isoflavones
3 Licorice
3 Lactoferrin/Talactoferrin
3 nicotinamide adenine dinucleotide
3 Radio Frequency
3 Sulfasalazine
3 Taurine
3 Vitamin B1/Thiamine
2 1,8-Cineole
2 2-DeoxyGlucose
2 Glucose
2 Zinc
2 Andrographis
2 Anti-oxidants
2 Vitamin A, Retinoic Acid
2 Aromatherapy
2 Astaxanthin
2 Arsenic trioxide
2 Baicalin
2 Huperzine A/Huperzia serrata
2 Beta-Caryophyllene
2 Bufalin/Huachansu
2 temozolomide
2 probiotics
2 brusatol
2 Vitexin
2 Isovitexin
2 Rutin
2 Caffeic Acid Phenethyl Ester (CAPE)
2 Caffeine
2 Calcium
2 Celecoxib
2 Hydroxycinnamic-acid
2 Calorie Restriction Mimetics
2 Cyclopamine
2 Dichloroacetophenone(2,2-)
2 Deguelin
2 Date Fruit Extract
2 diet Ketogenic
2 Oxygen, Hyperbaric
2 D-limonene
2 statins
2 Emodin
2 Vitamin E
2 ferumoxytol
2 Paclitaxel/Taxol
2 SDG/lignans
2 tamoxifen
2 Garcinol
2 Geldanamycin
2 γ-linolenic acid (Borage Oil)
2 Grapeseed extract
2 Orlistat
2 hydroxychloroquine
2 Helleborus niger extracts – Christmas Rose
2 Hyperoside
2 itraconazole
2 Potassium
2 lambertianic acid
2 Lapachol
2 Methylene blue
2 Methyl Jasmonate
2 Magnesium
2 Mistletoe/Viscum album Extracts
2 Naringin
2 Marjoram (Origanum majorana)
2 Rauwolfia serpentina/Indian Snakeroot
2 Aflavin-3,3′-digallate
2 tetrathiomolybdate
2 Ursolic acid
1 5-Aminolevulinic acid
1 Anzaroot, Astragalus fasciculifolius Bioss
1 wortmannin
1 Resiquimod
1 Aidi injection
1 Acetyl-l-carnitine
1 Phyllanthus emblica/Emblica officinalis/Amla / Indian Gooseberry
1 Amodiaquine
1 DTS(dibenzyl trisulphide) from Anamu
1 Anethole/trans-Anethole
1 Fennel Oil/Foeniculum vulgare
1 Sorafenib (brand name Nexavar)
1 Trastuzumab
1 Biochanin A
1 Brucea javanica
1 Bacopa monnieri
1 Bromelain
1 Bruteridin(bergamot juice)
1 urea
1 Cannabichromene
1 Beta‐Lapachone
1 Cinnamon
1 Carica papaya leaf extract
1 Camptothecin
1 irinotecan
1 Carvone
1 Polyphenols
1 Black phosphorus
1 Cucurbitacin
1 gefitinib, erlotinib
1 Dasatinib/Phyrago
1 Dihydrocaffeic Acid
1 diet Fermented Foods
1 Dipyridamole
1 Protocatechuic acid
1 PXD, phenoxodiol
1 Eurycomanone
1 flavonoids
1 Flickering Light Stimulation
1 Flaxseed Oil
1 Galloflavin
1 verapamil
1 Salvia officinalis
1 Germanium inorganic
1 Geraniol
1 Germanium-Spirogermanium
1 Ginkgetin
1 Glabrescione B
1 Graviola
1 High-Ozonide Oil
1 Indole-3-carbinol
1 entinostat
1 Recombinant Methioninase
1 Lactobacillus
1 Laetrile B17 Amygdalin
1 Lapatinib
1 low dose naltrexone
1 Lecithin
1 Linalool
1 Mung Bean Sprouts
1 Modified Citrus Pectin
1 carboplatin
1 Methylglyoxal
1 magnetic nanoparticles
1 Mushroom Lion’s Mane
1 Mushroom Reishi
1 Myricetin
1 No Product/Mechanism Only
1 Oleocanthal
1 Peppermint
1 sericin
1 Phosphatidylserine
1 Pumpkin Seed Oil / Cucurbita pepo
1 Tamsulosin
1 enzalutamide
1 Rhein
1 Oxaliplatin
1 α-Santalol/Sandalwood oil
1 Scoulerine
1 polyethylene glycol
1 Iron
1 Squalene
1 Glutathione
1 Sutherlandioside D
1 Triphala
1 triptolide
1 Tumor Treating Fields
1 Turmerones
1 Vitamin B3,Niacin
1 Vitamin B5,Pantothenic Acid
1 Vitamin B6,pyridoxine
1 Wogonin
Query results interpretion may depend on "conditions" listed in the research papers.
Such Conditions may include : 
  -low or high Dose
  -format for product, such as nano of lipid formations
  -different cell line effects
  -synergies with other products 
  -if effect was for normal or cancerous cells

Filter Conditions: Pro/AntiFlg:%  IllCat:%  CanType:%  Cells:%  prod#:%  Target#:961  State#:%  Dir#:%
  wNotes=0  sortOrder:rid,rpid

 

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