| 6155- | CoQ10, | BPGbio Highlights Groundbreaking Data on BPM31510 for Mitochondrial Diseases at the Inaugural Mitochondrial Transplantation and Next Generation Therapeutics Conference |
| - | Review, | NA, | NA |
| - | in-vitro, | Colon, | Caco-2 |
| 6158- | CoQ10, | Coenzyme Q10 Ameliorates Pancreatic Fibrosis via the ROS-Triggered mTOR Signaling Pathway |
| - | in-vitro, | NA, | NA |
| 6157- | CoQ10, | BPM31510: Targeting the tumor microenvironment (TME) via mitochondrial-mediated ROS production |
| - | Review, | GBM, | NA |
| 6156- | CoQ10, | Metabolic Regulation of Ferroptosis in Breast Cancer |
| - | Review, | Var, | NA |
| 6154- | CoQ10, | Coenzyme Q10 (BPM31510-IV in clinical trials) increases mitochondrial Q-pool and modulates electron transport chain function to elicit cell death in pancreatic cancer cells |
| - | vitro+vivo, | PC, | MIA PaCa-2 |
| - | vitro+vivo, | GBM, | U251 |
| 6152- | CoQ10, | doxoR, | Phase I Randomized, Placebo-Controlled, Cross-Over Dose-Finding Study of Coenzyme Q10 on Doxorubicin Pharmacokinetics during Breast Cancer Treatment |
| - | Trial, | BC, | NA |
| 6368- | CPLE, | Carica Papaya Leaf Extract to Improve Chemotherapy-Induced Thrombocytopenia: A Phase III Triple-Blinded, Randomized, Placebo-Controlled, Multicentric Trial |
| - | Trial, | Var, | NA |
| 6407- | CPLE, | Animal Trials of Carica Papaya Leaf Extracts for Increasing Platelet Count |
| - | Review, | Nor, | NA |
| - | Trial, | Var, | NA |
| 6370- | CPLE, | Delving into the Therapeutic Potential of Carica papaya Leaf against Thrombocytopenia |
| - | Review, | Var, | NA |
| 6371- | CPLE, | Carica papaya L. Leaf: A Systematic Scoping Review on Biological Safety and Herb-Drug Interactions |
| - | Review, | Nor, | NA |
| 6372- | CPLE, | Anti-proliferation and Apoptosis Induction of Aqueous Leaf Extract of Carica papaya L. on Human Breast Cancer Cells MCF-7 |
| - | in-vitro, | BC, | MCF7 |
| 6373- | CPLE, | Anticancer Activity of Phytochemicals of the Papaya Plant Assessed: A Narrative Review |
| - | Review, | Var, | NA |
| 6374- | CPLE, | Antiviral & platelet-protective properties of Carica papaya in dengue |
| - | Review, | Nor, | NA |
| 6375- | CPLE, | Beneficial Role of Carica papaya Extracts and Phytochemicals on Oxidative Stress and Related Diseases: A Mini Review |
| - | Review, | Var, | NA |
| 5810- | CPT, | CPT-11, | Camptothein-Based Anti-Cancer Therapies and Strategies to Improve Their Therapeutic Index |
| - | Review, | NA, | NA |
| 5809- | CPT, | Cancer Therapies Utilizing the Camptothecins: A Review of in Vivo Literature |
| - | Review, | Var, | NA |
| 5808- | CPT, | Repair of Topoisomerase I-Mediated DNA Damage |
| - | Review, | Var, | NA |
| 5807- | CPT, | The mechanism of topoisomerase I poisoning by a camptothecin analog |
| - | Study, | NA, | NA |
| 5780- | CRMs, | HCAs, | RES, | Sper, | ASA | Caloric Restriction Mimetics against Age-Associated Disease: Targets, Mechanisms, and Therapeutic Potential |
| - | Review, | Var, | NA |
| 5791- | CRMs, | HCA, | NAD, | Sper, | RES | Caloric Restriction Mimetics in Nutrition and Clinical Trials |
| - | Review, | Nor, | NA |
| 5792- | CRMs, | HCA, | CUR, | EGCG, | GAR | Caloric restriction mimetics: natural/physiological pharmacological autophagy inducers |
| - | Review, | Nor, | NA |
| 5798- | CRMs, | Caloric restriction mimetics improve gut microbiota: a promising neurotherapeutics approach for managing age-related neurodegenerative disorders |
| - | Review, | Nor, | NA | - | Review, | AD, | NA |
| 5801- | CRMs, | Chemo, | Caloric Restriction Enhances Chemotherapy Efficacy and Reshapes Stress Responses in Sarcoma |
| - | in-vivo, | sarcoma, | NA |
| 6181- | Cro, | Crocetin: A Systematic Review |
| - | Review, | Var, | NA | - | Review, | AD, | NA |
| 6180- | Cro, | New findings in the metabolism of the saffron apocarotenoids, crocins and crocetin, by the human gut microbiota |
| - | Study, | Nor, | NA |
| 6179- | Cro, | Crocetin suppresses the growth and migration in HCT-116 human colorectal cancer cells by activating the p-38 MAPK signaling pathway |
| - | NA, | CRC, | HCT116 |
| 6178- | Cro, | Exploring the therapeutic efficacy of crocetin in oncology: an evidence-based review |
| - | Review, | Var, | NA |
| 6291- | Cro, | Crocetin inhibits pancreatic cancer cell proliferation and tumor progression in a xenograft mouse model |
| - | vitro+vivo, | PC, | MIA PaCa-2 | - | vitro+vivo, | PC, | Bxpc-3 | - | vitro+vivo, | PC, | Capan1 | - | vitro+vivo, | PC, | AsPC-1 |
| 6316- | Cro, | Crocin suppresses prostate cancer progression via TLR4/NF-κB and NLRP3 pathway inhibition |
| - | vitro+vivo, | Pca, | LNCaP | - | in-vitro, | Pca, | 22Rv1 |
| 6315- | Cro, | Functional Mechanisms of Dietary Crocin Protection in Cardiovascular Models under Oxidative Stress |
| - | in-vivo, | NA, | NA |
| 6314- | Cro, | Crocin promotes ferroptosis in gastric cancer via the Nrf2/GGTLC2 pathway |
| - | in-vitro, | GC, | NA |
| 6313- | Cro, | Crocetin and related oxygen diffusion‐enhancing compounds: Review of chemical synthesis, pharmacology, clinical development, and novel therapeutic applications |
| - | Review, | Covid, | NA | - | Review, | Var, | NA | - | Review, | Stroke, | NA |
| 6312- | Cro, | Crocin from Crocus Sativus Possesses Significant Anti-Proliferation Effects on Human Colorectal Cancer Cells |
| - | in-vitro, | CRC, | HCT116 | - | in-vitro, | CRC, | SW48 | - | in-vitro, | CRC, | HT29 |
| 6311- | Cro, | Intestinal Metabolism of Crocin and a Pharmacokinetics and Pharmacodynamics Study in the Chronic Social Defeat Stress Mouse Model |
| - | in-vivo, | Nor, | NA |
| 6310- | Cro, | Characterization of Crocetin Isomers in Serum Samples via UHPLC-DAD-MS/MS and NMR after Saffron Extract (Safr’Inside™) Consumption |
| - | in-vivo, | Nor, | NA |
| 6309- | Cro, | Crocin exerts anti-tumor effect in colon cancer cells via repressing the JaK pathway |
| - | in-vitro, | CRC, | HCT116 |
| 6308- | Cro, | Dietary Crocin is Protective in Pancreatic Cancer while Reducing Radiation-Induced Hepatic Oxidative Damage |
| - | vitro+vivo, | PC, | Bxpc-3 |
| 6307- | Cro, | Effects of Intestinal Microbiota on Pharmacokinetics of Crocin and Crocetin in Male Sprague-Dawley Rats |
| - | in-vivo, | Nor, | NA |
| 6306- | Cro, | Crocetin induces apoptosis of BGC-823 human gastric cancer cells |
| - | in-vitro, | GC, | BGC-823 |
| 6305- | Cro, | Bridging Preclinical and Clinical Evidence on Crocin in Breast Cancer |
| - | Review, | BC, | NA |
| 6304- | Cro, | Crocin attenuates NF-κB-mediated inflammation and proliferation in breast cancer cells by down-regulating PRKCQ |
| - | in-vitro, | BC, | NA |
| 6334- | Cro, | Eug, | Rad, | Crocin and eugenol enhance radiosensitivity in oral squamous cell carcinoma cells via apoptotic pathways and cell cycle regulation. Type of study: in vitro |
| - | in-vitro, | OS, | NA |
| 6303- | Cro, | Crocetin treatment inhibits proliferation of colon cancer cells through down-regulation of genes involved in the inflammation |
| - | in-vitro, | CRC, | HCT116 | - | in-vitro, | CRC, | DU145 |
| 6302- | Cro, | Natural compounds as lactate dehydrogenase inhibitors: potential therapeutics for lactate dehydrogenase inhibitors-related diseases |
| - | Review, | NA, | NA |
| 6301- | Cro, | Crocin Inhibits Angiogenesis and Metastasis in Colon Cancer via TNF-α/NF-kB/VEGF Pathways |
| - | vitro+vivo, | Colon, | HT29 | - | in-vitro, | Colon, | Caco-2 |
| 6300- | Cro, | Interaction of saffron and its constituents with Nrf2 signaling pathway: A review |
| - | Review, | Nor, | NA | - | Review, | Arthritis, | NA |
| - | in-vivo, | Nor, | NA |
Query results interpretion may depend on "conditions" listed in the research papers. Such Conditions may include : -low or high Dose -format for product, such as nano of lipid formations -different cell line effects -synergies with other products -if effect was for normal or cancerous cells
Filter Conditions: Pro/AntiFlg:% IllCat:% CanType:% Cells:% prod#:% Target#:% State#:% Dir#:%
wNotes=0 sortOrder:rid,rpid