Cancer Database Query Results

Scientific Papers found: Click to Expand⟱

Lut,

Zeax,

Nutritional Intervention to Prevent Alzheimer's Disease: Potential Benefits of Xanthophyll Carotenoids and Omega-3 Fatty Acids Combined

Trial,

AD,

2; lutein:meso-zeaxanthin:zeaxanthin 10:10:2 mg/day plus 1 g/day of fish oil containing 430 mg docohexaenoic acid [DHA] and 90 mg eicopentaenoic acid [EPA]), respectively

*memory↑, *eff↑, *Mood↑,

3983-

Lut,

Zeax,

The impact of supplemental macular carotenoids in Alzheimer's disease: a randomized clinical trial

Trial,

AD,

*other↑, *other↑, *cognitive∅,

4193-

Lut,

Zeax,

Effects of a Lutein and Zeaxanthin Intervention on Cognitive Function: A Randomized, Double-Masked, Placebo-Controlled Trial of Younger Healthy Adults

Trial,

NA,

10 mg of L and 2 mg of Z

young (age 18–30), healthy adults

*MPOD↑, *cognitive↑, *memory↑,

4192-

Lut,

Zeax,

Lutein and Zeaxanthin Supplementation Improves Dynamic Visual and Cognitive Performance in Children: A Randomized, Double-Blind, Parallel, Placebo-Controlled Study

Trial,

NA,

10 mg lutein and 2 mg zeaxanthin (LZ)

Sixty children (age range 5–12 years)

*MPOD↑, *cognitive↑, *memory↑, *BDNF↑,

3896-

MCT,

Improvement of Main Cognitive Functions in Patients with Alzheimer's Disease after Treatment with Coconut Oil Enriched Mediterranean Diet: A Pilot Study

Trial,

AD,

coconut oil enriched Mediterranean diet for 21 days

*memory↑, *cognitive↑,

1781-

MEL,

Melatonin in patients with cancer receiving chemotherapy: a randomized, double-blind, placebo-controlled trial

Trial,

Lung,

QoL↑, OS∅, selectivity↑,

7494-

MEL,

Sul,

Medical and surgical treatments for tinnitus: the efficacy of combined treatment with sulodexide and melatonin

Trial,

Nor,

30 patients with tinnitus were treated with sulodexide (250 LSU BID, in the morning and in the evening) and melatonin (3 mg in the evening before going to sleep) for 80 days.

*Dose↝, *Tinn↓, *AntiThr↑,

4099-

MF,

Extremely low frequency electromagnetic field reduces oxidative stress during the rehabilitation of post-acute stroke patients

Trial,

Stroke,

57 post-stroke patients

*ROS↓,

4098-

MF,

Extremely low frequency electromagnetic field (ELF-EMF) reduces oxidative stress and improves functional and psychological status in ischemic stroke patients

Trial,

Stroke,

ELF-EMF field of 40 Hz, 7 mT for 15 min/day for 4 weeks (5 days a week)

post-stroke patients. Fifty-seven

*antiOx↑, *cognitive↑, *Dose↝,

4097-

MF,

Theta Frequency Electromagnetic Stimulation Enhances Functional Recovery After Stroke

Trial,

Stroke,

mice

*motorD↑, *eff↑, *Dose↝,

4095-

MF,

Frequency-tuned electromagnetic field therapy improves post-stroke motor function: A pilot randomized controlled trial

Trial,

Stroke,

*Dose↝, *motorD↑,

3478-

MF,

One Month of Brief Weekly Magnetic Field Therapy Enhances the Anticancer Potential of Female Human Sera: Randomized Double-Blind Pilot Study

Trial,

BC,

in-vitro,

BC,

MCF7

in-vitro,

Nor,

C2C12

TumCP↓, TumCMig↓, TumCI↓, *toxicity∅, TGF-β↓, Twist↓, Slug↓, β-catenin/ZEB1↓, Vim↓, p‑SMAD2↓, p‑SMAD3↓, angioG↓, VEGF↓, selectivity↑, LIF↑,

6939-

MF,

A prospective, randomized, placebo controlled, double-blind study of pelvic electromagnetic therapy for the treatment of chronic pelvic pain syndrome with 1 year of followup

Trial,

Nor,

 21 men with a mean age of 47.8 years

*Pain↓,

6936-

MF,

Ex,

Pulsed electromagnetic field with or without exercise therapy in the treatment of benign prostatic hyperplasia

Trial,

BPH,

Sixty male patients aged 55–65 years with benign prostatic hyperplasia

*eff↑, *eff↑, *BloodF↑, *Diff↝, *Dose↝, *Dose↝, *Dose↝, *Dose↝, *Dose↝, *Dose↝, *Dose↝, *UFR↑, *UR↓, *PSA↓, *other↑, *Inflam↓,

6941-

MF,

Ex,

The effects of pulsed electromagnetic field therapy on muscle strength and pain in patients with end-stage knee osteoarthritis: a randomized controlled trial

Trial,

Arthritis,

Sixty patients OA

*Strength↑, *Pain↓, *eff↑, *Dose↝,

4349-

MF,

Long-term effect of full-body pulsed electromagnetic field and exercise protocol in the treatment of men with osteopenia or osteoporosis: A randomized placebo-controlled trial

Trial,

ostP,

0.01–15,000 Hz, with sinusoidal, rectangular, multi-resonance, impulse, or sawtooth waveforms, the full-body maximum intensity is 30 gauss (3,000 microTesla)

Ninety-five males with osteopenia or osteoporosis

*BMD↑, *Pain↓, *QoL↑, *toxicity↓, *Dose↝, *Inflam↓,

782-

Mg,

Oral magnesium supplements for cancer treatment‐induced hypomagnesemia: Results from a pilot randomized trial

Trial,

Var,

*BioAv↑,

3851-

MSM,

Efficacy of methylsulfonylmethane (MSM) in osteoarthritis pain of the knee: a pilot clinical trial

Trial,

Arthritis,

3g twice a day

*Pain↓, *QoL↑,

2934-

NAD,

The efficacy and safety of β-nicotinamide mononucleotide (NMN) supplementation in healthy middle-aged adults: a randomized, multicenter, double-blind, placebo-controlled, parallel-group, dose-dependent clinical trial

Trial,

Nor,

80 participants

*Dose↑, *Strength↑,

5606-

NaHCO3,

Effects of Alkalization Therapy on Chemotherapy Outcomes in Metastatic or Recurrent Pancreatic Cancer

Trial,

PC,

Twenty-eight patients with metastatic or recurrent pancreatic cancer were assessed in this study

Dose↝, OS↑, eff↑,

5605-

NaHCO3,

A nonrandomized cohort and a randomized study of local control of large hepatocarcinoma by targeting intratumoral lactic acidosis

Trial,

HCC,

57 patients with large HCC) and a randomized controlled (20 patients with large HCC) study.

eff↑, Dose↝, other↓, OS↑, toxicity↓, AntiCan↓,

5255-

NCL,

Clinical safety and pharmacokinetics of a novel oral niclosamide formulation compared with marketed niclosamide chewing tablets in healthy volunteers: A three-part randomized, double-blind, placebo-controlled trial

Trial,

Nor,

Twenty-eight healthy subjects were enrolled in part A (12 subjects), part B (4 subjects), and part C (12 subjects), all completed the study according to protocol.

BioAv↝, Dose↝, toxicity↓, BioAv↑, BioAv↝,

7534-

OLE,

An oleuropein-based dietary supplement may improve joint functional capacity in older people with high knee joint pain: findings from a multicentre-RCT and post hoc analysis

Trial,

Arthritis,

*Pain↓, *Dose↝,

4648-

OLEC,

The Effect of Dietary Intervention With High-Oleocanthal and Oleacein Olive Oil in Patients With Early-Stage Chronic Lymphocytic Leukemia: A Pilot Randomized Trial

Trial,

CLL,

40 ml/day of high OC/OL-EVOO (416 mg/Kg OC and 284 mg/kg OL)

Apoptosis↑, *QoL↑,

2075-

PB,

Chemo,

Preliminary Findings on the Use of Targeted Therapy in Combination with Sodium Phenylbutyrate in Colorectal Cancer after Failure of Second-Line Therapy—A Potential Strategy for Improved Survival

Trial,

CRC,

OS↑, HDAC↓,

2026-

PB,

Oral sodium phenylbutyrate in patients with recurrent malignant gliomas: A dose escalation and pharmacologic study

Trial,

GBM,

Twenty-three patients with supratentorial recurrent malignant gliomas were enrolled on this dose escalation trial

Dose↝, Dose↑, Dose↝, OS↑, HDAC↓, TumCCA↑, P21↑, other↝, BioAv↑, eff↑,

2027-

PB,

Phase I dose escalation clinical trial of phenylbutyrate sodium administered twice daily to patients with advanced solid tumors

Trial,

Var,

TumCG↓, Dose↝, toxicity↓, Dose↝, HDAC↓, OS↑,

2038-

PB,

A phase I dose escalation and bioavailability study of oral sodium phenylbutyrate in patients with refractory solid tumor malignancies

Trial,

Var,

Dose∅, *toxicity↝, BioAv↑, SD↑,

1669-

PBG,

Chemo,

Antioxidant and anti-inflammatory effects of oral propolis in patients with breast cancer treated with chemotherapy: a Randomized controlled trial

Trial,

BC,

250 mg/ twice daily for 3 months

Breast cancer patients receiving chemotherapy were randomly assigned to two groups; a week prior to chemotherapy, the first group received Propolis (250 mg/ twice daily for 3 months) and the second group received a placebo daily.

antiOx↑, Inflam↓,

4924-

PEITC,

Nutri-PEITC Jelly Significantly Improves Progression-Free Survival and Quality of Life in Patients with Advanced Oral and Oropharyngeal Cancer: A Blinded Randomized Placebo-Controlled Trial

Trial,

Oral,

 consumed 200 g of Nutri-Jelly with and without 20 mg of PEITC

QoL↑, P53↑, OS↑, Cyt‑c↝, other↝, ROS↑, selectivity↑, P21↑, TumCCA↑, Dose↝, BioAv↑, Weight↑, chemoP↑,

4938-

PEITC,

Clinical Trial of 2-Phenethyl Isothiocyanate as an Inhibitor of Metabolic Activation of a Tobacco-Specific Lung Carcinogen in Cigarette Smokers

Trial,

Nor,

 1-week treatment period, each subject took PEITC (10 mg in 1 mL of olive oil, 4 times per day).

*Risk↑, *P450↓, *BioAv↑, *BioAv↑, *BioAv↑, *Dose↝, Dose↝,

6874-

Phen,

Blueberry phenolics are associated with cognitive enhancement in supplemented healthy older adults

Trial,

Nor,

(90 days) supplementation of freeze-dried BB (24 g d-1, equivalent to 1 cup of fresh BB)

*other↑, *cognitive↑, *Dose↝,

5630-

ProBio,

Bif,

EFFICACY OF PROBIOTICS IN PREVENTING CHEMOTHERAPY-INDUCED DIARRHEA IN GASTROINTESTINAL CANCER PATIENTS

Trial,

GC,

Dose↝, Diar⇅,

5624-

ProBio,

Bif,

A randomized double-blind placebo-controlled trial of probiotics in post-surgical colorectal cancer

Trial,

Testi,

Fifty-two patients with colorectal cancer were randomized at four weeks after surgery to receive either a placebo

Dose↝, TNF-α↓, IL6↓, IL10↓, IL12↓, IL22↓, toxicity↓,

6879-

PS,

aLinA,

Effects of a food supplement containing phosphatidylserine on cognitive function in Chinese older adults with mild cognitive impairment: A randomized double-blind, placebo-controlled trial

Trial,

Nor,

190 participants (mean [SD] age, 67.95 [5.62] years;

*Dose↝, *cognitive↑, *memory↑, *DHA↑, *EP2↑, *Ach↑,

3915-

PS,

Positive effects of soy lecithin-derived phosphatidylserine plus phosphatidic acid on memory, cognition, daily functioning, and mood in elderly patients with Alzheimer's disease and dementia

Trial,

AD,

 (300 mg PS + 240 mg PA/day) or placebo

*memory↑, *cognitive↑, *Half-Life↝, *Mood↑,

3914-

PS,

Soybean-Derived Phosphatidylserine Improves Memory Function of the Elderly Japanese Subjects with Memory Complaints

Trial,

AD,

(100 mg, 300 mg/day) or placebo for 6 months.

*memory↑, *cognitive↑, *lipid-P↓, *antiOx↑, *Inflam↓,

3925-

PTS,

Analysis of Safety from a Human Clinical Trial with Pterostilbene

Trial,

NA,

*toxicity↓, *Half-Life↑, *BioAv↑,

3606-

QC,

The Effect of Quercetin on Inflammatory Factors and Clinical Symptoms in Women with Rheumatoid Arthritis: A Double-Blind, Randomized Controlled Trial

Trial,

Arthritis,

500 mg/day

50 women with RA

*motorD↑, *Pain↓, *TNF-α↓, *IL8↓, *IL6↓, *IL1β↓, *NF-kB↓, *p38↓,

3611-

QC,

Quercetin and vitamin C supplementation: effects on lipid profile and muscle damage in male athletes

Trial,

Nor,

60 males for eight weeks

*eff↝, *LDH↓,

3334-

QC,

Pharmacokinetics of Quercetin Absorption from Apples and Onions in Healthy Humans

Trial,

Nor,

*Half-Life↑,

5969-

Rad,

CET,

Radiotherapy plus cetuximab for locoregionally advanced head and neck cancer: 5-year survival data from a phase 3 randomised trial, and relation between cetuximab-induced rash and survival

Trial,

HNSCC,

Dose↝, radioP↑, OS↑,

5971-

Rad,

CET,

Radiotherapy plus cetuximab for squamous-cell carcinoma of the head and neck

Trial,

HNSCC,

OS↑,

5268-

Ramu,

A Study of Ramucirumab (LY3009806) Versus Placebo in Participants With Hepatocellular Carcinoma and Elevated Baseline Alpha-Fetoprotein (REACH-2)

Trial,

HCC,

other↝,

5285-

Ramu,

docx,

A randomized, double-blind, phase II study of ramucirumab plus docetaxel vs placebo plus docetaxel in Japanese patients with stage IV non-small cell lung cancer after disease progression on platinum-based therapy

Trial,

NSCLC,

OS↑,

5788-

RES,

Calorie restriction-like effects of 30 days of Resveratrol (resVida™) supplementation on energy metabolism and metabolic profile in obese humans

Trial,

Nor,

11 healthy, obese men with placebo and 150 mg/day resveratrol in a randomized double-blind cross-over study for 30 days.

*AMPK↑, *SIRT1↑, *PGC-1α↑, *BP↓, *CRM↑, *Dose↝, *mtDam↓, *ALAT↓, *hepatoP↑,

6810-

RF,

SUMMARY OF SAFETY AND PROBABLE BENEFIT (SSPB)

Trial,

HCC,

Dose↝, Dose↝, Dose↝, OS↑,

6808-

RF,

Safety and Efficacy of amplitude-modulated radiofrequency electromagnetic fields in advanced hepatocellular carcinoma

Trial,

HCC,

OS↑, *toxicity↓, Dose↝, TumCG↓, Dose↝, Dose↝, Dose↝, eff↑,

3621-

RosA,

Short-Term Study on the Effects of Rosemary on Cognitive Function in an Elderly Population

Trial,

AD,

Twenty-eight older adults (mean age, 75 years)

*cognitive↑, *Dose↝, *BioAv↑,

3638-

Sage,

Salvia officinalis extract in the treatment of patients with mild to moderate Alzheimer's disease: a double blind, randomized and placebo-controlled trial

Trial,

AD,

(60 drops/day

*cognitive↑,

Showing Research Papers: 251 to 300 of 334
Prev Page 6 of 7 Next

* indicates research on normal cells as opposed to diseased cells
Total Research Paper Matches: 334

Pathway results for Effect on Cancer / Diseased Cells:

Infection & Microbiome(tgid=24) ⓘ

Diar⇅, 1,
Total Targets: 48

Pathway results for Effect on Normal Cells:

NA, unassigned(tgid=0) ⓘ

Tinn↓, 1, UFR↑, 1, UR↓, 1,

Redox & Oxidative Stress(tgid=1) ⓘ

antiOx↑, 2, lipid-P↓, 1, MPOD↑, 2, ROS↓, 1,

Mitochondria & Bioenergetics(tgid=3) ⓘ

mtDam↓, 1, PGC-1α↑, 1,

Core Metabolism/Glycolysis(tgid=4) ⓘ

ALAT↓, 1, AMPK↑, 1, CRM↑, 1, DHA↑, 1, LDH↓, 1, SIRT1↑, 1,

Cell Death(tgid=5) ⓘ

p38↓, 1,

Transcription & Epigenetics(tgid=7) ⓘ

Ach↑, 1, AntiThr↑, 1, other↑, 4,

Proliferation, Differentiation & Cell State(tgid=12) ⓘ

Diff↝, 1, EP2↑, 1,

Immune & Inflammatory Signaling(tgid=16) ⓘ

IL1β↓, 1, IL6↓, 1, IL8↓, 1, Inflam↓, 3, NF-kB↓, 1, PSA↓, 1, TNF-α↓, 1,

Synaptic & Neurotransmission(tgid=18) ⓘ

BDNF↑, 1,

Drug Metabolism & Resistance(tgid=21) ⓘ

BioAv↑, 6, Dose↑, 1, Dose↝, 19, eff↑, 5, eff↝, 1, Half-Life↑, 2, Half-Life↝, 1, P450↓, 1,

Clinical Biomarkers(tgid=22) ⓘ

ALAT↓, 1, BloodF↑, 1, BMD↑, 1, BP↓, 1, IL6↓, 1, LDH↓, 1, PSA↓, 1,

Functional Outcomes(tgid=23) ⓘ

cognitive↑, 10, cognitive∅, 1, hepatoP↑, 1, memory↑, 7, Mood↑, 2, motorD↑, 3, Pain↓, 6, QoL↑, 3, Risk↑, 1, Strength↑, 2, toxicity↓, 3, toxicity↝, 1, toxicity∅, 1,
Total Targets: 57

Query results interpretion may depend on "conditions" listed in the research papers.
Such Conditions may include : 
  -low or high Dose
  -format for product, such as nano of lipid formations
  -different cell line effects
  -synergies with other products 
  -if effect was for normal or cancerous cells

Filter Conditions: Pro/AntiFlg:%  IllCat:%  CanType:%  Cells:%  prod#:%  Target#:%  State#:%  Dir#:%
  wNotes=0  sortOrder:rid,rpid

Cancer Database Query Results

Pathway results for Effect on Cancer / Diseased Cells:

Redox & Oxidative Stress(tgid=1) ⓘ

Cell Death(tgid=5) ⓘ

Transcription & Epigenetics(tgid=7) ⓘ

DNA Damage & Repair(tgid=10) ⓘ

Cell Cycle & Senescence(tgid=11) ⓘ

Proliferation, Differentiation & Cell State(tgid=12) ⓘ

Migration(tgid=13) ⓘ

Angiogenesis & Vasculature(tgid=14) ⓘ

Immune & Inflammatory Signaling(tgid=16) ⓘ

Drug Metabolism & Resistance(tgid=21) ⓘ

Clinical Biomarkers(tgid=22) ⓘ

Functional Outcomes(tgid=23) ⓘ

Infection & Microbiome(tgid=24) ⓘ

Pathway results for Effect on Normal Cells:

NA, unassigned(tgid=0) ⓘ

Redox & Oxidative Stress(tgid=1) ⓘ

Mitochondria & Bioenergetics(tgid=3) ⓘ

Core Metabolism/Glycolysis(tgid=4) ⓘ

Cell Death(tgid=5) ⓘ

Transcription & Epigenetics(tgid=7) ⓘ

Proliferation, Differentiation & Cell State(tgid=12) ⓘ

Immune & Inflammatory Signaling(tgid=16) ⓘ

Synaptic & Neurotransmission(tgid=18) ⓘ

Drug Metabolism & Resistance(tgid=21) ⓘ

Clinical Biomarkers(tgid=22) ⓘ

Functional Outcomes(tgid=23) ⓘ

Home Page