ER Stress Cancer Research Results

ER Stress, endoplasmic reticulum (ER) stress signaling pathway: Click to Expand ⟱
Source:
Type:
Protein expression of ATF, GRP78, and GADD153 which is a hall marker of ER stress.
The endoplasmic reticulum (ER) stress signaling pathway plays a crucial role in maintaining cellular homeostasis and responding to various stressors, including those encountered in cancer. When cells experience stress, such as the accumulation of misfolded proteins, they activate a series of signaling pathways collectively known as the unfolded protein response (UPR). The UPR aims to restore normal function by enhancing the protein-folding capacity of the ER, degrading misfolded proteins, and, if the stress is unresolved, triggering apoptosis.
The activation of ER stress pathways can contribute to resistance against chemotherapy and targeted therapies. Cancer cells may utilize the UPR to survive treatment-induced stress, making it challenging to achieve effective therapeutic outcomes.

-ER stress-associated proteins include: phosphorylation of PERK, eIF2α, ATF4, CHOP and cleaved-caspase 12
Scientific Papers found: Click to Expand⟱
3002- RosA,    Anticancer Effects of Rosemary (Rosmarinus officinalis L.) Extract and Rosemary Extract Polyphenols
- Review, Var, NA
TumCG↓, TumCP↓, TumCCA↑, ChemoSen↑, NRF2↑, PERK↑, SESN2↑, HO-1↑, cl‑Casp3↑, ROS↑, UPR↑, ER Stress↑, CHOP/DDIT3↑, HER2/EBBR2↓, ER-α36↓, PSA↓, BAX↑, AR↓, P-gp/ABCB1↓, Cyt‑c↑, HSP70/HSPA5↑, eff↑, p‑Akt↓, p‑mTOR↓, p‑P70S6K↓, cl‑PARP↑, eff↑,
3033- RosA,    Rosemary (Rosmarinus officinalis) Extract Modulates CHOP/GADD153 to Promote Androgen Receptor Degradation and Decreases Xenograft Tumor Growth
- in-vitro, Pca, 22Rv1 - in-vitro, Pca, LNCaP - vitro+vivo, NA, NA
ER Stress↑, selectivity↑, AR↓, TumCG↓, TumCCA↑, CHOP/DDIT3↑, PERK↓, GRP78/BiP↑, PSA↓,
4898- Sal,    Salinomycin as a potent anticancer stem cell agent: State of the art and future directions
- Review, Var, NA
CSCs↓, AntiCan↑, ChemoSen↑, RadioS↑, Wnt↓, MAPK↓, TumAuto↑, ATP↓, ROS↑, DNAdam↑, ER Stress↑, CSCsMark↓, Iron↑, *toxicity↝,
5003- Sal,    Salinomycin, as an autophagy modulator-- a new avenue to anticancer: a review
- Review, Var, NA
CSCs↓, TumAuto↑, selectivity↑, DNAdam↑, TumCCA↑, P-gp/ABCB1↓, Wnt↓, β-catenin/ZEB1↓, RadioS↑, ChemoSen↑, Shh↓, eff↓, ROS↑, AMPK↑, JNK↑, ER Stress↑,
4999- Sal,    Salinomycin triggers endoplasmic reticulum stress through ATP2A3 upregulation in PC-3 cells
- in-vitro, Pca, PC3
Bacteria↓, CSCs↓, ER Stress↑,
4908- Sal,    Salinomycin triggers prostate cancer cell apoptosis by inducing oxidative and endoplasmic reticulum stress via suppressing Nrf2 signaling
- in-vitro, Pca, PC3 - in-vitro, Pca, DU145
tumCV↓, ROS↑, lipid-P↑, UPR↑, ER Stress↑, NRF2↓, NADPH↓, HO-1↓, SOD↓, Catalase↓, GPx↓, eff↓, TumCP↓,
4912- Sal,    Salinomycin induces cell death with autophagy through activation of endoplasmic reticulum stress in human cancer cells
- in-vitro, Lung, A549 - in-vitro, Lung, H460 - in-vitro, Lung, Calu-1 - in-vitro, Lung, H157
CSCs↓, TumAuto↑, ER Stress↑, TumCD↑, ATF4↑, CHOP/DDIT3↑, AKT1↓, mTOR↓,
5125- Sal,    Salinomycin induced ROS results in abortive autophagy and leads to regulated necrosis in glioblastoma
- in-vitro, GBM, NA
ER Stress↑, UPR↑, autoF↓, lysosome↝, ROS↑, lipid-P↑, CSCs↓, necrosis↑, ATP↓, MMP↓, MOMP↑, DNAdam↑, AIF↑, lysoMP↑, MitoP↑, Ca+2↑,
1388- Sco,    Scoulerine promotes cell viability reduction and apoptosis by activating ROS-dependent endoplasmic reticulum stress in colorectal cancer cells
- in-vitro, CRC, NA
tumCV↓, Apoptosis↑, Casp3↑, Casp7↑, BAX↑, Bcl-2↓, ROS↑, GSH↓, SOD↓, ER Stress↑, GRP78/BiP↑, CHOP/DDIT3↑, eff↓,
2549- SDT,    Landscape of Cellular Bioeffects Triggered by Ultrasound-Induced Sonoporation
- Review, Var, NA
sonoP↑, tumCV↓, MMP↓, ROS↑, Ca+2↑, eff↝, eff↑, selectivity↑, Half-Life↝, Dose↝, P-gp/ABCB1↓, ER Stress↑, other↑,
4605- SeNPs,    Selenium nanoparticles: An insight on its Pro-oxidant andantioxidant properties
- Review, NA, NA
*antiOx↑, *selenoP↑, *Dose↝, *toxicity↓, ROS↑, ER Stress↑,
4603- SeNPs,    Therapeutic applications of selenium nanoparticles
- Review, Var, NA
AntiCan↑, Imm↑, *AntiDiabetic↑, *antiOx↑, *Inflam↓, ROS↑, ER Stress↑, DNAdam↑, *toxicity↓, *eff↑, *BioAv↑, selectivity↑, TumCCA↑, Risk↓, *lipid-P↓, *TNF-α↓, *CRP↓, TumMeta↓, angioG↓, selectivity↑, eff↑, *eff↑,
4453- SeNPs,    Selenium Nanoparticles: Green Synthesis and Biomedical Application
- Review, NA, NA
*toxicity↓, *Bacteria↓, ROS↑, MMP↓, ER Stress↑, P53↑, Apoptosis↑, Casp9↑, DNAdam↑, TumCCA↑, eff↑, Catalase↓, SOD↓, GSH↓, selectivity↓, selectivity↑, PCNA↓, eff↑, *ALAT↓, *AST↓, *ALP↓, *creat↓, *Inflam↓, *toxicity↓, selectivity↑,
3180- SFN,    Exploring the therapeutic effects of sulforaphane: an in-depth review on endoplasmic reticulum stress modulation across different disease contexts
- Review, Var, NA
*cardioP↑, *ER Stress↓, GRP78/BiP↑, XBP-1↑, Apoptosis↑, *NRF2↑, UPR↑,
3181- SFN,    Effect of sulforaphane on protein expression of Bip/GRP78 and caspase-12 in human hapetocelluar carcinoma HepG-2 cells
- in-vitro, HCC, HepG2
GRP78/BiP↑, Casp12↑, Apoptosis↑, ER Stress↑,
1458- SFN,    Sulforaphane Impact on Reactive Oxygen Species (ROS) in Bladder Carcinoma
- Review, Bladder, NA
HDAC↓, eff↓, TumW↓, TumW↓, angioG↓, *toxicity↓, GutMicro↝, AntiCan↑, ROS↑, MMP↓, Cyt‑c↑, Bax:Bcl2↑, Casp3↑, Casp9↑, Casp8∅, cl‑PARP↑, TRAIL↑, DR5↑, eff↓, NRF2↑, ER Stress↑, COX2/PTGS2↓, EGFR↓, HER2/EBBR2↓, ChemoSen↑, NF-kB↓, TumCCA?, p‑Akt↓, p‑mTOR↓, p70S6↓, p19↑, P21↑, CD44↓, CSCs↓,
1482- SFN,    Sulforaphane induces apoptosis in T24 human urinary bladder cancer cells through a reactive oxygen species-mediated mitochondrial pathway: the involvement of endoplasmic reticulum stress and the Nrf2 signaling pathway
- in-vitro, Bladder, T24/HTB-9
tumCV↓, Apoptosis↑, Cyt‑c↑, Bax:Bcl2↑, Casp9↑, Casp3↑, Casp8∅, cl‑PARP↑, ROS↑, MMP↓, eff↓, ER Stress↑, p‑NRF2↑, HO-1↑,
1480- SFN,    Sulforaphane Induces Cell Death Through G2/M Phase Arrest and Triggers Apoptosis in HCT 116 Human Colon Cancer Cells
- in-vitro, CRC, HCT116
tumCV↓, TumCCA↑, Apoptosis↑, cycA1/CCNA1↑, CycB/CCNB1↑, CDC25↓, CDK1↓, ROS↑, eff↓, Cyt‑c↑, AIF↑, ER Stress↑,
2231- SK,    Shikonin Exerts Cytotoxic Effects in Human Colon Cancers by Inducing Apoptotic Cell Death via the Endoplasmic Reticulum and Mitochondria-Mediated Pathways
- in-vitro, CRC, SNU-407
Apoptosis↑, ER Stress↑, PERK↑, eIF2α↑, CHOP/DDIT3↑, mt-Ca+2↑, MMP↓, Bcl-2↓, Casp3↑, Casp9↑, ERK↑, JNK↑, p38↓,
2228- SK,    Shikonin induced Apoptosis Mediated by Endoplasmic Reticulum Stress in Colorectal Cancer Cells
- in-vitro, CRC, HCT116 - in-vitro, CRC, HCT15 - in-vivo, NA, NA
Apoptosis↑, Bcl-2↓, Casp3↑, Casp9↑, cl‑PARP↑, GRP78/BiP↑, PERK↑, eIF2α↑, ATF4↑, CHOP/DDIT3↑, JNK↑, eff↓, ER Stress↑, ROS↑, TumCG↓,
2229- SK,    Shikonin induces apoptosis and prosurvival autophagy in human melanoma A375 cells via ROS-mediated ER stress and p38 pathways
- in-vitro, Melanoma, A375
Apoptosis↑, TumAuto↑, TumCP↓, TumCCA↑, P21↑, cycD1/CCND1↓, ER Stress↑, p‑eIF2α↑, CHOP/DDIT3↑, cl‑Casp3↑, p38↑, LC3B-II↑, Beclin-1↑, ROS↑, eff↓,
2217- SK,    Shikonin Inhibits Endoplasmic Reticulum Stress-Induced Apoptosis to Attenuate Renal Ischemia/Reperfusion Injury by Activating the Sirt1/Nrf2/HO-1 Pathway
- in-vivo, Nor, NA - in-vitro, Nor, HK-2
*ER Stress↓, *SIRT1↑, *NRF2↑, *HO-1↑, *eff↓, *RenoP↑, *GRP78/BiP↓, *CHOP/DDIT3↓, *Casp12↓, *BAX↓, *cl‑Casp3↓,
1002- SSE,  Osi,  Adag,    Selenite as a dual apoptotic and ferroptotic agent synergizes with EGFR and KRAS inhibitors with epigenetic interference
- in-vitro, Lung, H1975 - in-vitro, Lung, H385
Apoptosis↑, Ferroptosis↑, DNMT1↓, TET1↑, TumCCA↑, cl‑PARP↑, cl‑Casp3↑, Cyt‑c↑, BIM↑, NOXA↑, Apoptosis↑, ROS↑, ER Stress↑, UPR↑,
5074- SSE,    Application of Sodium Selenite in the Prevention and Treatment of Cancers
- Review, Var, NA
Imm↑, angioG↑, DNArepair↑, NK cell↑, ROS↑, AntiCan↑, selectivity↑, ER Stress↑, TumAuto↑, necrosis↑, toxicity↝, Dose↑,
5107- SSE,    Involvement of p38 in signal switching from autophagy to apoptosis via the PERK/eIF2α/ATF4 axis in selenite-treated NB4 cells
- vitro+vivo, AML, APL NB4
PERK↑, eIF2α↑, ATF4↑, Apoptosis↑, AntiTum↑, ER Stress↑, p38↑,
5105- SSE,    Sodium selenite induces apoptosis by generation of superoxide via the mitochondrial-dependent pathway in human prostate cancer cells
- in-vitro, Pca, LNCaP
TumCD↑, Apoptosis↑, ROS↑, eff↓, MMP↓, Cyt‑c↑, Casp3↑, Casp9↑, ER Stress↑, TumAuto↑, necrosis↑, chemoPv↑,
3950- Taur,    Taurine Supplementation as a Neuroprotective Strategy upon Brain Dysfunction in Metabolic Syndrome and Diabetes
- Review, Diabetic, NA - Review, Stroke, NA - Review, AD, NA
*Ca+2↝, *neuroP↑, *other↝, *pH↝, *ROS∅, eff↑, *MMP↑, *Apoptosis↓, *other↝, *ER Stress↓, *Bcl-xL↓, *BAX↑, *Cyt‑c↑, *cal2↓, *Casp3↓, *UPR↓, *other↝, *NF-kB↓, *NRF2↑, *GLUT1↑, *GLUT3↑, *memory↑,
3417- TQ,    Antiproliferative Effects of Thymoquinone in MCF-7 Breast and HepG2 Liver Cancer Cells: Possible Role of Ceramide and ER Stress
- in-vitro, BC, MCF7 - in-vitro, Liver, HepG2
TumCP↓, NF-kB↓, cl‑Casp3↑, GRP78/BiP↑, ER Stress↑, Apoptosis↑,
3416- TQ,    Thymoquinone induces apoptosis in bladder cancer cell via endoplasmic reticulum stress-dependent mitochondrial pathway
- in-vitro, Bladder, T24/HTB-9 - in-vitro, Bladder, 253J - in-vitro, Nor, SV-HUC-1
TumCP↓, Apoptosis↑, ER Stress↑, cl‑Casp3↑, cl‑Casp8↑, cl‑Casp7↑, cl‑PARP↑, Cyt‑c↑, PERK↑, IRE1↑, ATF6↑, p‑eIF2α↑, ATF4↑, GRP78/BiP↑, CHOP/DDIT3↑,
4835- Uro,    Urolithin A, induces apoptosis and autophagy crosstalk in Oral Squamous Cell Carcinoma via mTOR /AKT/ERK1/2 pathway
- in-vitro, SCC, NA
TumCD↑, ER Stress↑, Akt↓, mtDam↓, p‑mTOR↓, *BioAv↝, ROS↑, TumCCA↑, Apoptosis↑, ERK↓,
3146- VitC,    Vitamin C protects against hypoxia, inflammation, and ER stress in primary human preadipocytes and adipocytes
- in-vivo, Nor, NA
*Obesity↓, *ER Stress↓, *Inflam↓, Hif1a↓, VEGF↓, GLUT1↓, GRP78/BiP↓,
3147- VitC,    Vitamin C modulates the metabolic and cytokine profiles, alleviates hepatic endoplasmic reticulum stress, and increases the life span of Gulo−/− mice
- in-vivo, Nor, NA
*OS↑, *ER Stress↓, *GRP78/BiP↓,
3149- VitC,    Hepatoprotective benefits of vitamin C against perfluorooctane sulfonate-induced liver damage in mice through suppressing inflammatory reaction and ER stress
- in-vivo, Nor, NA
*hepatoP↑, *ALAT↓, *AST↓, *TNF-α↓, *IL6↓, *ER Stress↓, *ATF6↓, *eIF2α↓, *GRP78/BiP↓, *XBP-1↓, *Inflam↓,
3107- VitC,    Repurposing Vitamin C for Cancer Treatment: Focus on Targeting the Tumor Microenvironment
- Review, Var, NA
Risk↓, *ROS↓, ROS↑, VEGF↓, COX2/PTGS2↓, ER Stress↑, IRE1↑, JNK↑, CHOP/DDIT3↑, Hif1a↓, eff↑, Glycolysis↓, MMPs↓, TumMeta↓, YAP/TEAD↓, eff↑, TET1↑,
3110- VitC,    Vitamin C Attenuates Oxidative Stress, Inflammation, and Apoptosis Induced by Acute Hypoxia through the Nrf2/Keap1 Signaling Pathway in Gibel Carp (Carassius gibelio)
- in-vivo, Nor, NA
*IL2↑, *IL6↑, *IL12↑, *NRF2↑, *Catalase↑, *SOD↑, *GPx↑, *GRP78/BiP↓, *ER Stress↓,
2283- VitK2,    Vitamin K Contribution to DNA Damage—Advantage or Disadvantage? A Human Health Response
- Review, Var, NA
*ER Stress↓, *toxicity↓, *toxicity↑, ROS↑, PI3K↑, Akt↑, Hif1a↑, GlucoseCon↑, lactateProd↑, ChemoSen↑, eff↑, eff↑,

Showing Research Papers: 251 to 286 of 286
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* indicates research on normal cells as opposed to diseased cells
Total Research Paper Matches: 286

Pathway results for Effect on Cancer / Diseased Cells:


Redox & Oxidative Stress(tgid=1) ⓘ

Catalase↓, 2,   Ferroptosis↑, 1,   GPx↓, 1,   GSH↓, 2,   HO-1↓, 1,   HO-1↑, 2,   Iron↑, 1,   lipid-P↑, 2,   NRF2↓, 1,   NRF2↑, 2,   p‑NRF2↑, 1,   ROS↑, 21,   SOD↓, 3,  

Mitochondria & Bioenergetics(tgid=3) ⓘ

AIF↑, 2,   ATP↓, 2,   CDC25↓, 1,   MMP↓, 7,   mtDam↓, 1,  

Core Metabolism/Glycolysis(tgid=4) ⓘ

AKT1↓, 1,   AMPK↑, 1,   GlucoseCon↑, 1,   Glycolysis↓, 1,   lactateProd↑, 1,   NADPH↓, 1,  

Cell Death(tgid=5) ⓘ

Akt↓, 1,   Akt↑, 1,   p‑Akt↓, 2,   Apoptosis↑, 16,   BAX↑, 2,   Bax:Bcl2↑, 2,   Bcl-2↓, 3,   BIM↑, 1,   Casp12↑, 1,   Casp3↑, 6,   cl‑Casp3↑, 5,   Casp7↑, 1,   cl‑Casp7↑, 1,   Casp8∅, 2,   cl‑Casp8↑, 1,   Casp9↑, 6,   Cyt‑c↑, 7,   DR5↑, 1,   Ferroptosis↑, 1,   JNK↑, 4,   lysoMP↑, 1,   MAPK↓, 1,   MOMP↑, 1,   necrosis↑, 3,   NOXA↑, 1,   p38↓, 1,   p38↑, 2,   TRAIL↑, 1,   TumCD↑, 3,   YAP/TEAD↓, 1,  

Kinase & Signal Transduction(tgid=6) ⓘ

HER2/EBBR2↓, 2,   p70S6↓, 1,  

Transcription & Epigenetics(tgid=7) ⓘ

other↑, 1,   tumCV↓, 5,  

Protein Folding & ER Stress(tgid=8) ⓘ

ATF6↑, 1,   CHOP/DDIT3↑, 9,   eIF2α↑, 3,   p‑eIF2α↑, 2,   ER Stress↑, 28,   GRP78/BiP↓, 1,   GRP78/BiP↑, 7,   HSP70/HSPA5↑, 1,   IRE1↑, 2,   PERK↓, 1,   PERK↑, 5,   UPR↑, 5,   XBP-1↑, 1,  

Autophagy & Lysosomes(tgid=9) ⓘ

autoF↓, 1,   Beclin-1↑, 1,   LC3B-II↑, 1,   lysosome↝, 1,   MitoP↑, 1,   SESN2↑, 1,   TumAuto↑, 6,  

DNA Damage & Repair(tgid=10) ⓘ

DNAdam↑, 5,   DNArepair↑, 1,   DNMT1↓, 1,   P53↑, 1,   cl‑PARP↑, 6,   PCNA↓, 1,  

Cell Cycle & Senescence(tgid=11) ⓘ

CDK1↓, 1,   cycA1/CCNA1↑, 1,   CycB/CCNB1↑, 1,   cycD1/CCND1↓, 1,   p19↑, 1,   P21↑, 2,   TumCCA?, 1,   TumCCA↑, 9,  

Proliferation, Differentiation & Cell State(tgid=12) ⓘ

CD44↓, 1,   CSCs↓, 6,   CSCsMark↓, 1,   ERK↓, 1,   ERK↑, 1,   HDAC↓, 1,   mTOR↓, 1,   p‑mTOR↓, 3,   p‑P70S6K↓, 1,   PI3K↑, 1,   Shh↓, 1,   TumCG↓, 3,   Wnt↓, 2,  

Migration(tgid=13) ⓘ

Ca+2↑, 2,   mt-Ca+2↑, 1,   ER-α36↓, 1,   MMPs↓, 1,   TET1↑, 2,   TumCP↓, 5,   TumMeta↓, 2,   β-catenin/ZEB1↓, 1,  

Angiogenesis & Vasculature(tgid=14) ⓘ

angioG↓, 2,   angioG↑, 1,   ATF4↑, 4,   EGFR↓, 1,   Hif1a↓, 2,   Hif1a↑, 1,   VEGF↓, 2,  

Barriers & Transport(tgid=15) ⓘ

GLUT1↓, 1,   P-gp/ABCB1↓, 3,   sonoP↑, 1,  

Immune & Inflammatory Signaling(tgid=16) ⓘ

COX2/PTGS2↓, 2,   Imm↑, 2,   NF-kB↓, 2,   NK cell↑, 1,   PSA↓, 2,  

Hormonal & Nuclear Receptors(tgid=20) ⓘ

AR↓, 2,  

Drug Metabolism & Resistance(tgid=21) ⓘ

ChemoSen↑, 5,   Dose↑, 1,   Dose↝, 1,   eff↓, 10,   eff↑, 11,   eff↝, 1,   Half-Life↝, 1,   RadioS↑, 2,   selectivity↓, 1,   selectivity↑, 8,  

Clinical Biomarkers(tgid=22) ⓘ

AR↓, 2,   EGFR↓, 1,   GutMicro↝, 1,   HER2/EBBR2↓, 2,   PSA↓, 2,  

Functional Outcomes(tgid=23) ⓘ

AntiCan↑, 4,   AntiTum↑, 1,   chemoPv↑, 1,   Risk↓, 2,   toxicity↝, 1,   TumW↓, 2,  

Infection & Microbiome(tgid=24) ⓘ

Bacteria↓, 1,  
Total Targets: 151

Pathway results for Effect on Normal Cells:


Redox & Oxidative Stress(tgid=1) ⓘ

antiOx↑, 2,   Catalase↑, 1,   GPx↑, 1,   HO-1↑, 1,   lipid-P↓, 1,   NRF2↑, 4,   ROS↓, 1,   ROS∅, 1,   selenoP↑, 1,   SOD↑, 1,  

Mitochondria & Bioenergetics(tgid=3) ⓘ

MMP↑, 1,  

Core Metabolism/Glycolysis(tgid=4) ⓘ

ALAT↓, 2,   SIRT1↑, 1,  

Cell Death(tgid=5) ⓘ

Apoptosis↓, 1,   BAX↓, 1,   BAX↑, 1,   Bcl-xL↓, 1,   Casp12↓, 1,   Casp3↓, 1,   cl‑Casp3↓, 1,   Cyt‑c↑, 1,  

Transcription & Epigenetics(tgid=7) ⓘ

other↝, 3,  

Protein Folding & ER Stress(tgid=8) ⓘ

ATF6↓, 1,   CHOP/DDIT3↓, 1,   eIF2α↓, 1,   ER Stress↓, 8,   GRP78/BiP↓, 4,   UPR↓, 1,   XBP-1↓, 1,  

Migration(tgid=13) ⓘ

Ca+2↝, 1,   cal2↓, 1,  

Barriers & Transport(tgid=15) ⓘ

GLUT1↑, 1,   GLUT3↑, 1,  

Immune & Inflammatory Signaling(tgid=16) ⓘ

CRP↓, 1,   IL12↑, 1,   IL2↑, 1,   IL6↓, 1,   IL6↑, 1,   Inflam↓, 4,   NF-kB↓, 1,   TNF-α↓, 2,  

Cellular Microenvironment(tgid=17) ⓘ

pH↝, 1,  

Drug Metabolism & Resistance(tgid=21) ⓘ

BioAv↑, 1,   BioAv↝, 1,   Dose↝, 1,   eff↓, 1,   eff↑, 2,  

Clinical Biomarkers(tgid=22) ⓘ

ALAT↓, 2,   ALP↓, 1,   AST↓, 2,   creat↓, 1,   CRP↓, 1,   IL6↓, 1,   IL6↑, 1,  

Functional Outcomes(tgid=23) ⓘ

AntiDiabetic↑, 1,   cardioP↑, 1,   hepatoP↑, 1,   memory↑, 1,   neuroP↑, 1,   Obesity↓, 1,   OS↑, 1,   RenoP↑, 1,   toxicity↓, 6,   toxicity↑, 1,   toxicity↝, 1,  

Infection & Microbiome(tgid=24) ⓘ

Bacteria↓, 1,  
Total Targets: 66

Scientific Paper Hit Count for: ER Stress, endoplasmic reticulum (ER) stress signaling pathway
13 Silver-NanoParticles
13 Phenylbutyrate
12 Quercetin
11 Curcumin
11 Berberine
9 EGCG (Epigallocatechin Gallate)
9 Fisetin
8 Ashwagandha(Withaferin A)
7 Artemisinin
7 Chrysin
7 salinomycin
7 Gambogic Acid
7 Piperlongumine
6 Apigenin (mainly Parsley)
6 Magnetic Fields
6 Honokiol
6 Luteolin
5 Allicin (mainly Garlic)
5 Resveratrol
5 Rosmarinic acid
5 Sulforaphane (mainly Broccoli)
5 Vitamin C (Ascorbic Acid)
4 Baicalein
4 Betulinic acid
4 Capsaicin
4 Celastrol
4 Propolis -bee glue
4 Emodin
4 Electrical Pulses
4 Shikonin
4 Selenite (Sodium)
3 Photodynamic Therapy
3 Boron
3 Crocetin
3 Copper and Cu NanoParticles
3 Hydrogen Gas
3 HydroxyTyrosol
3 Nimbolide
3 Selenium NanoParticles
2 3-bromopyruvate
2 Andrographis
2 Cisplatin
2 Boswellia (frankincense)
2 Celecoxib
2 Isobavachalcone
2 Isovitexin
2 Plumbagin
2 Pterostilbene
2 Thymoquinone
1 5-Aminolevulinic acid
1 Auranofin
1 Astragalus
1 Radiotherapy/Radiation
1 Alpha-Lipoic-Acid
1 Melatonin
1 immunotherapy
1 Sorafenib (brand name Nexavar)
1 Aloe anthraquinones
1 Berbamine
1 Chemotherapy
1 Bacopa monnieri
1 α-Bisabolol / Chamomile oil
1 doxorubicin
1 Bortezomib
1 Carnosic acid
1 Carvacrol
1 carboplatin
1 Cannabidiol
1 chitosan
1 Choline
1 Cinnamon
1 Coenzyme Q10
1 Cynaropicrin
1 Dichloroacetate
1 Dipyridamole
1 Aspirin
1 Dandelion Root
1 Disulfiram
1 Ellagic acid
1 Ferulic acid
1 Fenbendazole
1 verapamil
1 Garcinol
1 γ-linolenic acid (Borage Oil)
1 Graviola
1 hydrogen sulfide
1 Hyperthermia
1 Indole-3-carbinol
1 Isoliquiritigenin
1 isoquercitrin
1 Vitexin
1 Lutein
1 Lycopene
1 Magnolol
1 Magnetic Field Rotating
1 Magnesium
1 Naringin
1 nelfinavir/Viracept
1 Docetaxel
1 Oroxylin-A
1 Oleuropein
1 temozolomide
1 Phenethyl isothiocyanate
1 Parthenolide
1 Paclitaxel/Taxol
1 Scoulerine
1 SonoDynamic Therapy UltraSound
1 Osimertinib
1 Adagrasib
1 Taurine
1 Urolithin
1 Vitamin K2
Query results interpretion may depend on "conditions" listed in the research papers.
Such Conditions may include : 
  -low or high Dose
  -format for product, such as nano of lipid formations
  -different cell line effects
  -synergies with other products 
  -if effect was for normal or cancerous cells

Filter Conditions: Pro/AntiFlg:%  IllCat:%  CanType:%  Cells:%  prod#:%  Target#:103  State#:%  Dir#:%
  wNotes=0  sortOrder:rid,rpid

 

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