ERK Cancer Research Results

ERK, ERK signaling: Click to Expand ⟱
Source:
Type:
MAPK3 (ERK1)
ERK proteins are kinases that activate other proteins by adding a phosphate group. An overactivation of these proteins causes the cell cycle to stop.
The extracellular signal-regulated kinase (ERK) signaling pathway is a crucial component of the mitogen-activated protein kinase (MAPK) signaling cascade, which plays a significant role in regulating various cellular processes, including proliferation, differentiation, and survival. high levels of phosphorylated ERK (p-ERK) in tumor samples may indicate active ERK signaling and could correlate with aggressive tumor behavior

EEk singaling is frequently activated and is often associated with aggressive tumor behavior, treatment resistance, and poor outcomes.
Scientific Papers found: Click to Expand⟱
8223- LCA,    Lico A Enhances Nrf2-Mediated Defense Mechanisms against t-BHP-Induced Oxidative Stress and Cell Death via Akt and ERK Activation in RAW 264.7 Cells
- in-vitro, Nor, RAW264.7
*Apoptosis↓, *ROS↓, *GSH↑, *GCLM↑, *GCLC↑, *HO-1↑, *NRF2↑, *Keap1↓, *ARE↑, *Akt↑, *ERK↑, *PI3K↑,
8284- LE,    Glycyrrhizic acid from licorice down-regulates inflammatory responses via blocking MAPK and PI3K/Akt-dependent NF-κB signalling pathways in TPA-induced skin inflammation
- in-vivo, Nor, NA
*Ingr↝, *iNOS↓, *COX2/PTGS2↓, *IκB↓, *p65↓, *ERK↓, *p38↓, *MAPK↓, *PI3K↓, *Akt↓, *NF-kB↓,
8279- LE,    18β-Glycyrrhetinic Acid Has Anti-Cancer Effects via Inducing Apoptosis and G2/M Cell Cycle Arrest, and Inhibiting Migration of A549 Lung Cancer Cells
- in-vitro, Lung, A549 - in-vitro, Lung, H23 - in-vitro, Lung, H460
tumCV↓, selectivity↑, Apoptosis↑, ROS↑, TumCCA↑, TumCMig↓, TumCP↓, MMP↓, BAD↑, Cyt‑c↑, cl‑Casp3↑, cl‑PARP↑, Bcl-2↓, p‑ERK↓, p‑STAT3↓, NF-kB↓,
8184- LGE,    Cytotoxicity of citral against melanoma cells: The involvement of oxidative stress generation and cell growth protein reduction
- in-vitro, Melanoma, B16-BL6 - in-vitro, Nor, HaCaT
TumCP↓, ROS↑, DNAdam↑, P53↝, NO↓, NF-kB↓, ERK↓, Akt↓, selectivity↑,
8292- lign,    Anticancer potential of flaxseed lignans, their metabolites and synthetic counterparts in relation with molecular targets: current challenges and future perspectives
- Review, Var, NA
*BioAv↝, chemoPv↑, Apoptosis↑, TumCP↓, TumMeta↓, angioG↓, *AntiDiabetic↑, *antiOx↑, *AntiCan↑, *Inflam↓, *cardioP↑, TumCCA↑, PSA↓, miR-106b↓, IGF-1↓, ERK↓, Akt↓, Bcl-2↓, p‑FAK↓, radioP↑, P-gp/ABCB1↓, ChemoSen↑, MMP↓, ROS↑, BioAv↓, *toxicity↓, chemoP↑,
8328- LIN,    Linalool inhibits the growth of human T cell acute lymphoblastic leukemia cells with involvement of the MAPK signaling pathway
- in-vitro, AML, NA
TumCG↓, selectivity?, p‑ERK↓, p‑JNK↑,
8384- LT,    Current situation and research progress of luteolin in the treatment of gastrointestinal malignant tumors
- Review, GC, NA
Apoptosis↑, TumAuto↑, TumCCA↑, EMT↓, *ROS↓, *antiOx↑, ROS↑, P53↑, LC3II↑, Beclin-1/ATG6↑, p‑MAP2K1/MEK1↓, p‑ERK↓, BAX↑, cl‑Casp3↑, Bcl-2↓, p‑MAPK↓, DNArepair↓, HMGB1↓, XRCC1↓, ERCC3↑, CycB/CCNB1↓, CDC2↓, p‑CHK1↑, TumCCA↑, TumCP?, Wnt↓, β-catenin/ZEB1↓, miR-384↑, PTN↓, MMP2↓, MMP3↓, MMP9↓, MMP16↓, Ferroptosis↑, GPx4↓, Synergy↑, Ki-67↓, GSH↓, ChemoSen↑, TumCP↓, TumCMig↓, TumCI↓, PI3K↓, Akt↓, mTOR↓, NF-kB↓, NOTCH↓, miR-139-5p↑, miR-34a↑, miR-422a↑, miR-107↑, miR-21↓, miR-155↓, miR-224↓, miR-340↓, E-cadherin↑, N-cadherin↓, Vim↓, HK1↓, FOXO1↓, compI↓, compIII↓, compV↓, ETC↓, BioAv↝,
8390- LT,    Luteolin in Inflammatory Bowel Disease and Colorectal Cancer: A Disease Continuum Perspective
- Review, IBD, NA - Review, CRC, NA
*Diff↝, *Inflam↓, *ROS↓, *GutMicro↑, *IBI↑, TumCP↓, Apoptosis↑, TumCMig↓, TumCI↓, *BioAv↑, *iNOS↓, *TNF-α↓, *IL6↓, *MDA↓, *lipid-P↓, *antiOx↑, *NRF2↑, *HO-1↑, *NQO1↑, *SOD↑, *Catalase↑, *5HT↓, *TPH1↓, *MAPK↓, *ERK↓, *Inflam↓, cycD1/CCND1↓, CDK4↓, TumCCA↑, Casp3↑, Casp9↑, PI3K↓, Akt↓, p‑Akt↓, p‑mTOR↓, E-cadherin↑, N-cadherin↓, Vim↓,
2923- LT,    Luteolin induces apoptosis through endoplasmic reticulum stress and mitochondrial dysfunction in Neuro-2a mouse neuroblastoma cells
- in-vitro, neuroblastoma, NA
Apoptosis↑, TumCD↑, Casp12↑, Casp9↑, Casp3↑, ER Stress↑, CHOP/DDIT3↑, GRP78/BiP↑, GRP94↑, cl‑ATF6↑, p‑eIF2α↑, MMP↓, JNK↓, p38↑, ERK↑, Cyt‑c↑,
2906- LT,    Luteolin, a flavonoid with potentials for cancer prevention and therapy
- Review, Var, NA
*Inflam↓, AntiCan↑, antiOx⇅, Apoptosis↑, TumCP↓, TumMeta↓, angioG↓, PI3K↓, Akt↓, NF-kB↓, XIAP↓, P53↑, *ROS↓, *GSTA1↑, *GSR↑, *SOD↑, *Catalase↑, *other↓, ROS↑, Dose↝, chemoP↑, NF-kB↓, JNK↑, p27/CDKN1B↑, P21↑, DR5↑, Casp↑, Fas↑, BAX↑, MAPK↓, CDK2↓, IGF-1↓, PDGF↓, EGFR↓, PKCδ↓, TOP1↓, TOP2↓, Bcl-xL↓, FASN↓, VEGF↓, VEGFR2/KDR/Flk1↓, MMP9↓, Hif1a↓, FAK↓, MMP1↓, Twist↓, ERK↓, P450↓, CYP1A1↓, CYP1A2↓, TumCCA↑,
2908- LT,    Luteolin attenuates neutrophilic oxidative stress and inflammatory arthritis by inhibiting Raf1 activity
- in-vitro, Arthritis, NA
*ROS↓, *p‑ERK↓, *p‑MEK↓, *Raf↓,
2914- LT,    Therapeutic Potential of Luteolin on Cancer
- Review, Var, NA
*antiOx↑, *IronCh↑, *toxicity↓, *BioAv↓, *BioAv↑, DNAdam↑, TumCP↓, DR5↑, P53↑, JNK↑, BAX↑, cl‑Casp3↑, cl‑Casp8↑, cl‑Casp9↑, cl‑PARP↑, survivin↓, cycD1/CCND1↓, CycB/CCNB1↓, CDC2↓, P21↑, angioG↓, MMP2↓, AEG1↓, VEGF↓, VEGFR2/KDR/Flk1↓, MMP9↓, CXCR4↓, PI3K↓, Akt↓, ERK↓, TumAuto↑, LC3B-II↑, EMT↓, E-cadherin↑, N-cadherin↓, Wnt↓, ROS↑, NICD↓, p‑GSK‐3β↓, iNOS↓, COX2/PTGS2↓, NRF2↑, Ca+2↑, ChemoSen↑, ChemoSen↓, IFN-γ↓, RadioS↑, MDM2↓, NOTCH1↓, AR↓, TIMP1↑, TIMP2↑, ER Stress↑, CDK2↓, Telomerase↓, p‑NF-kB↑, p‑cMyc↑, hTERT/TERT↓, RAS↓, YAP/TEAD↓, TAZ↓, NF-kB↓, NRF2↓, HO-1↓, MDR1↓,
2916- LT,    Antioxidative and Anticancer Potential of Luteolin: A Comprehensive Approach Against Wide Range of Human Malignancies
- Review, Var, NA - Review, AD, NA - Review, Park, NA
proCasp9↓, CDC2↓, CycB/CCNB1↓, Casp9↑, Casp3↑, Cyt‑c↑, cycA1/CCNA1↑, CDK2↓, APAF1↑, TumCCA↑, P53↑, BAX↑, VEGF↓, Bcl-2↓, Apoptosis↑, p‑Akt↓, p‑EGFR↓, p‑ERK↓, p‑STAT3↓, cardioP↑, Catalase↓, SOD↓, *BioAv↓, *antiOx↑, *ROS↓, *NO↓, *GSTs↑, *GSR↑, *SOD↑, *Catalase↑, *lipid-P↓, PI3K↓, Akt↓, CDK2↓, BNIP3↑, hTERT/TERT↓, DR5↑, Beclin-1/ATG6↑, TNF-α↓, NF-kB↓, IL1↓, IL6↓, EMT↓, FAK↓, E-cadherin↑, MDM2↓, NOTCH↓, MAPK↑, Vim↓, N-cadherin↓, Snail↓, MMP2↓, Twist↓, MMP9↓, ROS↑, MMP↓, *AChE↓, *MMP↑, *Aβ↓, *neuroP↑, Trx1↑, ROS↓, *NRF2↑, NRF2↓, *BBB↑, ChemoSen↑, GutMicro↑, *antiAll↑, *Mucositis↓, *TregCell↑, *Beclin-1/ATG6↓, *PI3K↑, *Akt↑, *mTOR↑,
8345- Lut,    Lutein inhibits breast cancer cell growth by suppressing antioxidant and cell survival signals and induces apoptosis
- in-vitro, BC, MCF7 - in-vitro, BC, MDA-MB-231
tumCV↓, SOD2↓, HO-1↓, NRF2↓, p‑Akt↓, p‑ERK↓, NF-kB↓, Apoptosis↑, Casp3↑, Bcl-2↓, PARP↓, ROS↓, XBP-1↓, Dose↝, Risk↓, MMP↓, selectivity↑, p‑Akt↓,
8343- Lut,    Association of Lutein with Cancer: A Systematic Review of the Lutein Effects on Cellular Processes Involved in Cancer Progression
- Review, Var, NA
*antiOx↑, *Inflam↓, Risk↓, AntiCan∅, Apoptosis↑, ROS↓, NRF2↓, Akt↓, ERK↓, NF-kB↓, Bcl-2↓, BAX↑, Casp3↑, DNAdam↑, ROS↓, P53↑, PCNA↓, cycD1/CCND1↓, TumCP↓, Hif1a↓, NOTCH↓, miR-590-3p↑, TumCMig↓, TumCI↓, TumMeta↓, TumCA↓, *BioAv↓,
3264- Lyco,    Pharmacological potentials of lycopene against aging and aging‐related disorders: A review
- Review, Var, NA - Review, AD, NA - Review, Stroke, NA
*antiOx↑, *ROS↓, *SOD↑, *Catalase↑, *GSH↑, *GSTs↑, *MDA↓, *lipid-P↓, *NRF2↑, *HO-1↑, *iNOS↓, *NO↓, *TAC↑, *NOX4↓, *Inflam↓, *IL1↓, *IL6↓, *IL8↓, *IL1β↓, *TNF-α↓, *TLR2↓, *TLR4↓, *VCAM-1↓, *ICAM-1↓, *STAT3↓, *NF-kB↓, *ERK↓, *BP↓, ROS↓, PGE2↓, cardioP↑, *neuroP↑, *creat↓, *RenoP↑, *CRM↑,
3277- Lyco,    Recent trends and advances in the epidemiology, synergism, and delivery system of lycopene as an anti-cancer agent
- Review, Var, NA
antiOx↑, TumCP↓, Apoptosis↑, TumMeta↑, ChemoSen↑, BioAv↓, Dose↝, BioAv↓, BioAv↑, SOD↑, Catalase↑, GPx↑, IL2↑, IL4↑, IL1↑, TNF-α↑, GSH↑, GPx↑, GSTA1↑, GSR↑, PPARγ↑, Casp3↑, NF-kB↓, COX2/PTGS2↓, Bcl-2↑, BAX↓, P53↓, CHK1↓, Chk2↓, γH2AX↓, DNAdam↓, ROS↓, P21↑, PCNA↓, β-catenin/ZEB1↓, PGE2↓, ERK↓, cMyc↓, cycE/CCNE↓, JAK1↓, STAT3↓, SIRT1↑, cl‑PARP↑, cycD1/CCND1↓, TNF-α↓, IL6↓, p65↓, MMP2↓, MMP9↓, Wnt↓,
4786- Lyco,    Anti-proliferative and apoptosis-inducing activity of lycopene against three subtypes of human breast cancer cell lines
- in-vitro, BC, MDA-MB-468 - in-vitro, BC, MCF7 - in-vitro, BC, SkBr3
TumCP↓, TumCCA↑, cl‑PARP↑, ERK↑, cycD1/CCND1↓, P21↓, p‑Akt↓, mTOR↓, BAX↑, AntiCan↑, Risk↓,
4795- Lyco,    Updates on the Anticancer Profile of Lycopene and its Probable Mechanism against Breast and Gynecological Cancer
- Review, BC, NA
TumCG↓, TumCCA↑, Apoptosis↑, P53↝, BAX↝, cycD1/CCND1↓, ERK↓, Akt↓, STAT3↓, NRF2↝, NF-kB↓, ITGB1↓, ITGA5↓, FAK↓, MMP9↓, EMT↓,
4794- Lyco,    Anticancer Effect of Lycopene in Gastric Carcinogenesis
- Review, GC, NA
*AntiCan↑, *ROS↓, *GSH↑, *GPx↑, *GSTs↑, TumCG↓, Apoptosis↑, ERK↓, Bcl-2↓, BAX↑, Cyt‑c↑, TumCCA↑, *DNAdam↓,
4792- Lyco,    A Comprehensive Review on the Molecular Mechanism of Lycopene in Cancer Therapy
- Review, Var, NA
*AntiCan↑, *antiOx↑, Inflam↓, Wnt↓, β-catenin/ZEB1↓, *ROS↓, BioAv↑, ROS↓, Risk↓, PGE2↓, COX2/PTGS2↓, p‑ERK↓, P21↑, MMP7↓, MMP9↓, ChemoSen↑, Synergy↑,
8521- MAG,    Magnolol induces apoptosis via caspase-independent pathways in non-small cell lung cancer cells
- in-vitro, Lung, A549 - in-vitro, Lung, H520 - in-vitro, Lung, NCI-H441
TumCP↓, DNAdam↑, MMP↓, selectivity↑, BID↑, BAX↑, Cyt‑c↑, AIF↑, Endon↑, cl‑PARP↑, PI3K↓, Akt↓, ERK↓, p38↑, JNK↑,
8505- MAG,    Role of magnolol in gastrointestinal cancers: Recent trends and future perspectives
- Review, GC, NA
TumCP↓, TumCI↓, TumCMig↓, angioG↓, EMT↓, TumCCA↑, Apoptosis↑, PI3K↝, Akt↝, NF-kB↝, MAPK↝, JNK↝, ERK↝, TGF-β↝, Smad1↝,
8509- MAG,  Rad,    The In Vivo Radiosensitizing Effect of Magnolol on Tumor Growth of Hepatocellular Carcinoma
- in-vivo, HCC, NA
TumVol↓, TumW↓, *ERK↓, *NF-kB↓, Casp3↑, Casp9↑, RadioS↑, *toxicity↓, Ki-67↓, IL1β↓, TNF-α↓,
1089- MAG,    Magnolol potently suppressed lipopolysaccharide-induced iNOS and COX-2 expression via downregulating MAPK and NF-κB signaling pathways
- in-vitro, AML, RAW264.7
p‑IκB↓, NF-kB↓, p‑ERK↓, p‑JNK↓, p‑PI3K↓, p‑Akt↓, iNOS↓, COX2/PTGS2↓,
8561- Matr,    Matrine triggers colon cancer cell apoptosis and G0/G1 cell cycle arrest via mediation of microRNA-22
- in-vitro, Colon, SW480 - in-vitro, CRC, SW-620
Dose↝, tumCV↓, Apoptosis↑, TumCCA↑, miR-22↑, Wnt↓, β-catenin/ZEB1↓, MEK↓, ERK↓,
8555- Matr,    Matrine Exerts Pharmacological Effects Through Multiple Signaling Pathways: A Comprehensive Review
- Review, Var, NA
*AntiTum↑, *Inflam↓, *Analgesic↑, *AntiViral↑, *Imm↑, *PI3K↑, *Akt↑, *mTOR↑, TumAuto↑, PI3K↓, Akt↓, mTOR↓, Beclin-1/ATG6↑, E-cadherin↑, Vim↓, MMP2↓, MMP9↓, Snail↓, Slug↓, PTEN↑, TumCP↓, TumCMig↓, TumCI↓, ChemoSen↑, ROS↑, uPA↓, p‑ERK↓, cachexia↓, antiD↑, GSK‐3β↓, LC3B-II↑, p62↓, Apoptosis↑, Casp3↑, Casp8↑, Casp9↑, FOXO1↑, FOXO3↑, FOXO4↑, PARP↑, BIM↑, Bcl-2↓, survivin↓, miR-21↓, *HOTAIR↑, *p‑Akt↑, *p‑STAT3↑, *STAT3↑, *ROS↓, Wnt↓, β-catenin/ZEB1↓, NOTCH1↓, JAG1↓, HES1↓, BioAv↝, toxicity↝,
8547- Matr,    Matrine in cancer therapy: antitumor mechanisms and nano-delivery strategies
- Review, Var, NA
*Ingr↝, *AntiTum↑, Apoptosis↑, TumAuto↑, Ferroptosis↑, TumCP↓, TumCMig↓, TumCI↓, JPT1/HN1↓, Erlin1↑, LINC01116↓, miR-592↑, ERK↓, JAK↓, STAT3↓, miR-182-5p↓, PI3K↓, Akt↓, Wnt↓, β-catenin/ZEB1↓, Sharpin↓, ROS↓, AMPK↑, mTOR↓, Snail↓, Vim↓, N-cadherin↓, MMP2↓, MMP9↓, E-cadherin↑, PTEN↑, miR-10b-5p↓, GPx4↓, lipid-P↑, Iron↑, Piezo1↑,
8546- Matr,    Matrine Attenuates Neurological Deficits and Neuroinflammation by Inhibiting the HMGB1/RAGE Axis and Ferroptosis in Intracerebral Hemorrhage Mice
- in-vivo, Stroke, NA
*Dose?, *Stroke↓, *BBB↝, *TJ↑, *ZO-1↑, *OCLN↑, *CLDN4↑, *HMGB1↓, *RAGE↓, *JNK↓, *p38↓, *ERK↓, *NF-kB↓, *IL1β↓, *IL6↓, *TNF-α↓, *BAX↓, *Bcl-2↑, *Apoptosis↓, *Iron↓, *ACSL4↓, *GPx4↑, *Ferroptosis↓, *neuroP↑, *Inflam↓, *antiOx↑,
8635- MBZ,    The repurposed anthelmintic mebendazole in combination with trametinib suppresses refractory NRASQ61K melanoma
- vitro+vivo, Melanoma, NA
TumCCA↑, cMyc↓, cl‑Casp3↑, cl‑PARP↑, eff↑, TumCP↓, BRAF↓, OS↑, TumCG↓, p‑MEK↓, p‑ERK↓,
8715- MeJa,    Methyl jasmonate decreases membrane fluidity and induces apoptosis via tumor necrosis factor receptor 1 in breast cancer cells
- in-vitro, BC, MDA-MB-453 - in-vitro, BC, MCF-10AT
TumCG↓, TumCCA↑, memfluid↓, TNFR 1↑, MAPK↑, Casp8↑, MMP↓, Apoptosis↑, p38↑, ERK↑, Casp3↑,
8749- MeSA,  etoposide,    Methylseleninic acid enhances the effect of etoposide to inhibit prostate cancer growth in vivo
- in-vivo, Pca, NA
TumCG↓, Apoptosis↑, p‑ERK↓, p‑Akt↓, FABP5/E-FABP↓, angioG↓, VEGF↓, ChemoSen↑,
8743- MeSA,    PKB/AKT and ERK regulation of caspase-mediated apoptosis by methylseleninic acid in LNCaP prostate cancer cells
- in-vitro, Pca, LNCaP - in-vitro, Pca, DU145
Apoptosis↑, eff↝, p‑Akt↓, p‑ERK↑,
8742- MeSA,    Distinct effects of methylseleninic acid versus selenite on apoptosis, cell cycle, and protein kinase pathways in DU145 human prostate cancer cells
- in-vitro, Pca, DU145
TumCCA↑, DNAdam↑, Casp↑, cl‑PARP↑, p27/CDKN1B↑, P21↑, Apoptosis↑, Akt↓, ERK↓,
6539- MeSal,    Sodium salicylate induces apoptosis via p38 mitogen-activated protein kinase but inhibits tumor necrosis factor-induced c-Jun N-terminal kinase/stress-activated protein kinase activation
- in-vitro, Nor, NA
*NF-kB↓, *ERK↓,
2243- MF,    Pulsed electromagnetic fields increase osteogenetic commitment of MSCs via the mTOR pathway in TNF-α mediated inflammatory conditions: an in-vitro study
- in-vitro, Nor, NA
*eff↑, *mTOR↑, *Akt↑, *PKA↑, *MAPK↑, *ERK↑, *BMP2↑, *Diff↑, *PKCδ↓, *VEGF↑, *IL10↑,
2241- MF,    Pulsed electromagnetic therapy in cancer treatment: Progress and outlook
- Review, Var, NA
other↝, p‑ERK↝, P53↝, Cyt‑c↝, OXPHOS↑, Apoptosis↑, ROS↑,
4146- MF,    Pulsed electromagnetic field enhances brain-derived neurotrophic factor expression through L-type voltage-gated calcium channel- and Erk-dependent signaling pathways in neonatal rat dorsal root ganglion neurons
- in-vivo, AD, NA
*BDNF↑, *ERK↑,
4147- MF,    PEMFs Restore Mitochondrial and CREB/BDNF Signaling in Oxidatively Stressed PC12 Cells Targeting Neurodegeneration
- in-vitro, AD, PC12
*ROS↓, *Catalase↑, *MMP↑, *Casp3↓, *p‑ERK↓, *cAMP↑, *p‑CREB↑, *BDNF↑, *neuroP↑,
527- MF,    Effects of Fifty-Hertz Electromagnetic Fields on Granulocytic Differentiation of ATRA-Treated Acute Promyelocytic Leukemia NB4 Cells
- in-vitro, AML, APL NB4
ROS↑, other↑, p‑ERK↑, TumCP↓,
486- MF,    mTOR Activation by PI3K/Akt and ERK Signaling in Short ELF-EMF Exposed Human Keratinocytes
- in-vitro, Nor, HaCaT
*mTOR↑, *PI3K↑, *Akt↑, *p‑ERK↑, *other↑, *p‑JNK↑, *p‑P70S6K↑,
513- MF,    Exposure to a specific time-varying electromagnetic field inhibits cell proliferation via cAMP and ERK signaling in cancer cells
- in-vitro, BC, MDA-MB-231 - in-vitro, BC, MDA-MB-468 - in-vitro, BC, MCF7 - in-vivo, Pca, HeLa
TumCG↓, p‑ERK↑, cAMP⇅,
194- MF,    Electromagnetic Field as a Treatment for Cerebral Ischemic Stroke
- Review, Stroke, NA
*BAD↓, *BAX↓, *Casp3↓, *Bcl-xL↑, *p‑Akt↑, *MMP9↓, *p‑ERK↑, *HIF-1↓, *ROS↓, *VEGF↑, *Ca+2↓, *SOD↑, *IL2↑, *p38↑, *HSP70/HSPA5↑, *Apoptosis↓, *ROS↓, *NO↓,
189- MFrot,  MF,    Cancer treatment by magneto-mechanical effect of particles, a review
- Review, Var, NA
CellMemb↑, lysoMP↑, ERK↑, Apoptosis↑,
204- MFrot,  MF,    Rotating magnetic field improved cognitive and memory impairments in a sporadic ad model of mice by regulating microglial polarization
- in-vivo, AD, NA
*NF-kB↓, *MAPK↓, *TLR4↓, *memory↑, *cognitive↑, *TGF-β1↑, *ARG1/2↑, *IL4↑, *IL10↑, *IL6↓, *IL1↓, *TNF-α↓, *iNOS↓, *ROS↓, *NO↓, *MyD88↓, *p‑IKKα↓, *p‑IκB↓, *p‑p65↓, *p‑JNK↓, *p‑p38↓, *ERK↓, *neuroP↑, *Aβ↓,
8456- Mg,    Magnesium-L-threonate Ameliorates Cognitive Deficit by Attenuating Adult Hippocampal Neurogenesis Impairment in a Mouse Model of Alzheimer's Disease
- in-vivo, AD, NA
*neuroG↑, *memory↑, *p‑ERK↑, *p‑CREB↑, *CREB↓, *ERK↓, *cognitive↑,
8681- MLT,    Melatonin changes energy metabolism and reduces oncogenic signaling in ovarian cancer cells
- in-vitro, Ovarian, SKOV3
HIF-1↓, G6PD↓, GAPDH↓, PDH↓, CS↓, PFK1↓, LDH↓, PDH↑, lactateProd↓, glut↓, CREB↓, JNK↓, NF-kB↓, p38↓, ERK↓, Akt↓, P70S6K↓, STAT↓, Warburg↓, GlutaM↓,
8910- MO,    Moringa oleifera L. leaf extract induces cell cycle arrest and mitochondrial apoptosis in Dalton's Lymphoma: An in vitro and in vivo study
- vitro+vivo, lymphoma, NA
TumCP↓, MMP↓, TumCCA↑, P53↑, P21↑, BAX↑, Cyt‑c↑, Casp3↑, Bcl-2↑, Apoptosis↑, MEK↓, ERK↓,
8899- MOR,    Morin Inhibits Proliferation, Migration, and Invasion of Bladder Cancer EJ Cells via Modulation of Signaling Pathways, Cell Cycle Regulators, and Transcription Factor-Mediated MMP-9 Expression
- in-vivo, Bladder, NA
TumCP↓, TumCCA↑, cycD1/CCND1↓, cycE/CCNE↓, CDK2↓, CDK4↓, P21↑, p‑ERK↑, p‑JNK↓, p‑Akt↓, TumCMig↓, TumCI↓, MMP9↓, AP-1↓, Sp1/3/4↓, NF-kB↓,
8875- MOR,    Neuroprotective Effect of Morin Against Chemical-Induced Neurotoxicities and Neurodegenerative Disease Models
- Review, AD, NA
*neuroP↑, *Inflam↓, *antiOx↑, *chemoP↑, *NRF2↑, *HO-1↑, *SOD↑, *Catalase↑, *GPx↑, *GSH↑, *ROS↓, *MDA↓, *NO↓, *TLR4↓, *NF-kB↓, *ERK↓, *TNF-α↓, *IL1β↓, *IL6↓, *iNOS↓, *COX2/PTGS2↓, *NLRP3↓,

Showing Research Papers: 251 to 300 of 420
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* indicates research on normal cells as opposed to diseased cells
Total Research Paper Matches: 420

Pathway results for Effect on Cancer / Diseased Cells:


NA, unassigned(tgid=0) ⓘ

NA↑, 1,  

Redox & Oxidative Stress(tgid=1) ⓘ

4-HNE↑, 1,   antiOx↓, 1,   antiOx↑, 10,   antiOx⇅, 1,   Catalase↓, 4,   Catalase↑, 1,   ENOX2↓, 1,   Fenton↑, 3,   GPx↓, 1,   GPx↑, 3,   GPx4↓, 4,   GSH↓, 20,   GSH↑, 4,   GSH/GSSG↓, 1,   GSR↑, 1,   H2O2↑, 4,   HO-1↓, 8,   HO-1↑, 7,   HO-2↓, 1,   Iron↑, 3,   Keap1↓, 1,   lipid-P?, 1,   lipid-P↓, 7,   lipid-P↑, 7,   MDA↓, 2,   MDA↑, 3,   NOX4↓, 1,   NQO1↑, 1,   NRF2↓, 11,   NRF2↑, 10,   NRF2↝, 1,   Prx6↑, 1,   PYCR1↓, 1,   ROS?, 2,   ROS↓, 29,   ROS↑, 143,   ROS⇅, 8,   i-ROS↓, 1,   i-ROS↑, 2,   SAM-e↝, 1,   SOD↓, 6,   SOD↑, 6,   SOD1↑, 1,   SOD2↓, 1,   SOD2↑, 3,   Trx1↑, 1,   TrxR↓, 4,   TrxR1↓, 2,  

Metal & Cofactor Biology(tgid=2) ⓘ

FTH1↓, 1,   IronCh↑, 3,   Tf↓, 1,  

Mitochondria & Bioenergetics(tgid=3) ⓘ

ADP:ATP↑, 1,   CDC2↓, 8,   CDC2↑, 1,   CDC25↓, 11,   CDC25↑, 1,   compI↓, 1,   compIII↓, 1,   compV↓, 1,   CS↓, 1,   EGF↓, 6,   ETC↓, 1,   HSP60/HSPD1↓, 1,   Insulin↓, 1,   mitResp↓, 2,   MKK7↓, 1,   mtDam↓, 1,   mtDam↑, 7,   OCR↓, 3,   OCR↑, 1,   OXPHOS↑, 1,   PDH↓, 1,   PDH↑, 1,   SIRT3↑, 1,  

Core Metabolism/Glycolysis(tgid=4) ⓘ

12LOX?, 1,   12LOX↓, 2,   5LO↓, 1,   ACC↑, 1,   ACLY↓, 1,   ACSL4↑, 1,   ALAT↓, 4,   ALAT↝, 1,   AMPK↓, 1,   AMPK↑, 16,   p‑AMPK↑, 1,   ATP↓, 14,   CAIX/CA9↓, 1,   cAMP⇅, 1,   ECAR↓, 2,   ECAR↝, 1,   FABP5/E-FABP↓, 1,   FAO↑, 1,   FASN↓, 5,   FASN↑, 1,   G6PD↓, 1,   GAPDH↓, 1,   glucose↝, 1,   GlucoseCon↓, 5,   glut↓, 1,   GlutaM↓, 1,   Glycolysis↓, 20,   GSK‐3β↓, 6,   GSK‐3β↑, 3,   p‑GSK‐3β↓, 4,   ac‑Histones↑, 1,   HK1↓, 1,   HK2↓, 11,   HMG-CoA↓, 1,   HSD17B4↓, 1,   lactateProd↓, 7,   lactateProd↑, 1,   LDHA↓, 2,   LDL↓, 1,   lipoGen↓, 1,   NAD↝, 1,   NADPH↓, 1,   O-Glc↓, 1,   PCK1↓, 1,   PDK1 / PDPK1?, 2,   PDK1 / PDPK1↓, 3,   p‑PDK1 / PDPK1↓, 1,   PFK↓, 1,   PFK1↓, 2,   PFK2↓, 1,   PKM2↓, 8,   PKM2↑, 1,   p‑PKM2↓, 1,   Pyruv↓, 1,   p‑S6↓, 2,   SIRT1↓, 4,   SIRT1↑, 5,   SIRT2↑, 1,   SREBP1/SREBF1↓, 1,   SREBP2↓, 1,   TCA↓, 1,   TumCM/A↑, 1,   Warburg↓, 3,  

Cell Death(tgid=5) ⓘ

AIF↑, 7,   APAF1↑, 8,   Apoptosis?, 1,   Apoptosis↓, 6,   Apoptosis↑, 145,   mt-Apoptosis↑, 2,   ASK1↑, 1,   BAD↓, 2,   BAD↑, 8,   Bak↑, 7,   BAX↓, 2,   BAX↑, 97,   BAX↝, 1,   Bax:Bcl2↑, 27,   Bcl-2↓, 103,   Bcl-2↑, 6,   Bcl-xL↓, 20,   BID↓, 2,   BID↑, 7,   p‑BID↓, 1,   BIM↓, 1,   BIM↑, 6,   BNIP3↑, 2,   Casp↑, 21,   cl‑Casp↑, 1,   Casp1↓, 1,   Casp12?, 1,   Casp12↑, 1,   Casp2↑, 3,   Casp3↓, 6,   Casp3↑, 107,   cl‑Casp3↑, 19,   proCasp3↓, 1,   proCasp3↑, 1,   Casp6↑, 1,   Casp7↑, 13,   cl‑Casp7↑, 2,   Casp8↑, 34,   cl‑Casp8↑, 4,   Casp9↓, 1,   Casp9↑, 70,   cl‑Casp9↑, 9,   proCasp9↓, 1,   cFLIP↓, 7,   Cyt‑c↓, 1,   Cyt‑c↑, 65,   Cyt‑c↝, 2,   Diablo↑, 6,   DR5↑, 18,   Endon↑, 2,   FADD↑, 1,   Fas↑, 13,   FasL↑, 5,   FasL⇅, 1,   Ferroptosis↑, 7,   GranB/GZMB↑, 1,   GRP58↓, 1,   GSDME↑, 1,   IAP1↓, 5,   IAP2/BIRC3↓, 1,   cl‑IAP2/BIRC3↑, 1,   ICAD↓, 1,   iNOS↓, 16,   JWA↑, 1,   Mcl-1↓, 16,   p‑Mcl-1↓, 1,   MDM2↓, 8,   MDM2↑, 1,   p‑MDM2↓, 1,   Necroptosis↑, 3,   necrosis↑, 2,   NOXA↑, 2,   oncosis↑, 1,   p38↓, 16,   p38↑, 29,   p‑p38↓, 8,   p‑p38↑, 14,   p‑p38↝, 1,   Paraptosis↑, 1,   Perforin↑, 1,   PUMA↑, 2,   Pyro↑, 3,   RIP1↓, 2,   RIP1↑, 1,   RIP3↓, 1,   RIP3↑, 1,   survivin↓, 32,   TNFR 1↑, 1,   TRAIL↑, 4,   TRAILR↑, 1,   TumCD↑, 10,   XIAP↓, 15,   YAP/TEAD↓, 2,  

Kinase & Signal Transduction(tgid=6) ⓘ

Akt↓, 137,   Akt↑, 2,   Akt↝, 2,   Akt∅, 1,   p‑Akt↓, 47,   p‑Akt↑, 4,   AKT1↓, 1,   Akt2↓, 1,   BRAF↓, 1,   BRAF↝, 1,   CaMKII ↓, 1,   CaMKII ↑, 1,   CK2↓, 3,   cMET↓, 6,   p‑cMET↓, 1,   p‑cMET↑, 2,   CREB↓, 1,   p‑CREB↓, 1,   cSrc↓, 3,   EGFR↓, 49,   p‑EGFR↓, 4,   EphB4↓, 1,   ERK↓, 195,   ERK↑, 41,   ERK↝, 4,   ERK∅, 1,   p‑ERK↓, 79,   p‑ERK↑, 22,   p‑ERK⇅, 2,   p‑ERK↝, 2,   e-ERK↑, 1,   FGFR1↓, 2,   FOXD3↑, 1,   HER2/EBBR2↓, 9,   p‑HER2/EBBR2↓, 1,   HGF/c-Met↓, 2,   IGF-1R↓, 3,   IGFR↓, 2,   IKKα↓, 5,   IKKα↑, 2,   IKKα↝, 1,   p‑IKKα↓, 2,   IR↓, 1,   p‑IκB↓, 2,   JAK↓, 4,   p‑JAK↓, 1,   JAK1↓, 4,   JAK2↓, 11,   JNK↓, 14,   JNK↑, 34,   JNK↝, 1,   p‑JNK↓, 9,   p‑JNK↑, 15,   p‑JNK↝, 1,   cl‑JNK↑, 1,   MAP2K1/MEK1↓, 1,   p‑MAP2K1/MEK1↓, 1,   MAPK↓, 39,   MAPK↑, 21,   MAPK↝, 4,   p‑MAPK↓, 4,   p‑MAPK↑, 2,   MEK↓, 19,   MEK↑, 2,   p‑MEK↓, 6,   p‑MEK↑, 1,   MKK4↓, 1,   mTOR↓, 48,   p‑mTOR↓, 6,   mTORC2↓, 1,   p70S6↓, 1,   p‑p70S6↓, 1,   p‑p70S6↑, 1,   P70S6K↓, 6,   p‑P70S6K↓, 2,   p‑P90RSK↑, 1,   p‑PDGFR-BB↓, 1,   PI3K↓, 88,   PI3K↑, 1,   PI3K↝, 2,   p‑PI3K↓, 3,   PI3K/Akt↓, 5,   PI3K/Akt↑, 1,   PI3K/Akt↝, 1,   PI3k/Akt/mTOR↓, 2,   PIK3CA↓, 1,   p‑PIK3R1↓, 1,   PKCδ↓, 15,   PKCδ↑, 1,   p‑PKCδ↓, 1,   PP2A↑, 1,   PRAS40↑, 1,   PTEN↑, 19,   PTEN↝, 1,   p‑PTEN↓, 1,   PTK2B / PYK2↓, 1,   Raf↓, 12,   RAS↓, 16,   RAS↑, 1,   p‑RSK↓, 1,   S6K↓, 1,   p‑S6K↓, 1,   Sp1/3/4↓, 9,   Src↓, 2,   STAT↓, 3,   p‑STAT↓, 1,   STAT3↓, 52,   STAT3↝, 1,   p‑STAT3↓, 12,   p‑STAT3↑, 1,   STAT5↓, 1,   p‑STAT5↓, 1,   STAT6↓, 1,   THEM4/CTMP↑, 1,   TSC2↑, 2,  

Transcription & Epigenetics(tgid=7) ⓘ

ATF2↓, 1,   ATF3↑, 1,   ATF4↑, 6,   cJun↓, 6,   cJun↑, 1,   p‑cJun↓, 1,   p‑cJun↑, 2,   cMyc↓, 26,   p‑cMyc↑, 1,   DNMT1↓, 4,   DNMT3A↓, 1,   DNMTs↓, 3,   EZH2↓, 1,   FOXM1↓, 3,   FOXO↓, 1,   FOXO↑, 1,   FOXO1↓, 2,   FOXO1↑, 1,   FOXO3↓, 1,   FOXO3↑, 5,   p‑FOXO3↓, 1,   FOXO4↑, 2,   ac‑H3↑, 1,   ac‑H4↑, 1,   HATs↓, 1,   HATs↑, 2,   HDAC↓, 11,   HDAC1↓, 3,   HDAC2↓, 1,   HDAC4↓, 1,   HES1↓, 1,   JPT1/HN1↓, 1,   LINC01116↓, 1,   miR-106b↓, 1,   miR-107↑, 1,   miR-10b-5p↓, 1,   miR-139-5p↑, 1,   miR-155↓, 2,   miR-182-5p↓, 1,   miR-200b↑, 2,   miR-203↓, 1,   miR-203↑, 1,   miR-21↓, 3,   miR-21↑, 1,   miR-210↓, 1,   miR-210↑, 1,   miR-22↑, 1,   miR-224↓, 1,   miR-29b↑, 1,   miR-340↓, 1,   miR-34a↑, 3,   miR-384↑, 1,   miR-422a↑, 1,   miR-590-3p↑, 1,   miR-592↑, 1,   MITF↓, 1,   Myc↓, 4,   n-MYC↓, 1,   NDRG1↑, 1,   OCT4↓, 5,   other?, 2,   other↓, 4,   other↑, 4,   other↝, 6,   SOX2↓, 4,   SOX4↓, 1,   SOX9↓, 1,   SUV39H↓, 1,   TCF-4↓, 1,   TFAP2A↓, 1,   tumCV↓, 43,  

Protein Folding & ER Stress(tgid=8) ⓘ

ATF6↑, 2,   cl‑ATF6↑, 2,   CHOP/DDIT3↓, 1,   CHOP/DDIT3↑, 17,   eIF2α↓, 2,   eIF2α↑, 4,   p‑eIF2α↑, 4,   ER Stress↓, 2,   ER Stress↑, 25,   Erlin1↑, 1,   GRP78/BiP↓, 1,   GRP78/BiP↑, 10,   GRP94↑, 1,   HSP27↓, 4,   HSP27↑, 1,   HSP27↝, 1,   HSP70/HSPA5↓, 5,   HSP70/HSPA5↑, 1,   HSP70/HSPA5↝, 1,   HSP72↓, 1,   HSP90↓, 5,   HSPs↓, 2,   IRE1↑, 2,   PERK↑, 3,   p‑PERK↑, 1,   SERPINH1/HSP47↓, 1,   UPR↑, 5,   XBP-1↓, 2,  

Autophagy & Lysosomes(tgid=9) ⓘ

ATG13↑, 1,   ATG16L1↑, 1,   ATG3↑, 1,   ATG5↑, 5,   ATG7↑, 3,   Beclin-1/ATG6↑, 10,   CTSB↓, 1,   CTSD↓, 1,   LAMP2↓, 1,   LC3‑Ⅱ/LC3‑Ⅰ↑, 1,   LC3B-II↑, 4,   LC3I↑, 1,   LC3II↓, 2,   LC3II↑, 10,   lysoMP↑, 1,   p62↓, 5,   p62↑, 3,   RUBCN↓, 1,   TumAuto↑, 27,   ULK1/ATG1↑, 1,  

DNA Damage & Repair(tgid=10) ⓘ

ATM↑, 3,   p‑ATM↑, 1,   p‑ATR↑, 1,   BRCA1↓, 2,   BRCA1↑, 1,   p‑BRCA1↑, 1,   BRCA2↓, 1,   DNAdam↓, 2,   DNAdam↑, 39,   DNArepair↓, 4,   ERCC3↑, 1,   HR↓, 1,   hTERT/TERT↓, 9,   p16↑, 2,   P53?, 1,   P53↓, 3,   P53↑, 58,   P53↝, 3,   P53∅, 1,   p‑P53↑, 4,   ac‑P53↑, 1,   PARP↓, 3,   PARP↑, 12,   p‑PARP↑, 2,   cl‑PARP↑, 56,   PARP1↑, 2,   cl‑PARP1↑, 2,   PCNA↓, 18,   RAD51↓, 1,   SAPK↑, 1,   SIRT6↑, 1,   Telomerase↓, 13,   TOP1↓, 4,   TOP2↓, 6,   TOP2↑, 1,   TP53↑, 2,   UHRF1↓, 1,   XRCC1↓, 1,   γH2AX↓, 1,   γH2AX↑, 4,  

Cell Cycle & Senescence(tgid=11) ⓘ

CDK1↓, 14,   p‑CDK1↓, 1,   CDK2↓, 23,   CDK2↑, 1,   CDK4↓, 25,   CDK4↑, 1,   p‑CDK4↓, 1,   CDK4/6↓, 1,   CDK6↓, 11,   CDK6↑, 2,   CDK8↓, 1,   CHK1↓, 2,   p‑CHK1↑, 2,   Chk2↓, 2,   p‑Chk2↓, 1,   p‑Chk2↑, 1,   Cyc↓, 2,   cycA1/CCNA1↓, 5,   cycA1/CCNA1↑, 1,   CycB/CCNB1↓, 20,   CycB/CCNB1↑, 1,   cycD1/CCND1↓, 55,   cycD1/CCND1↑, 1,   p‑cycD1/CCND1↓, 1,   CycD3↓, 1,   cycE/CCNE↓, 11,   cycE/CCNE↑, 1,   cycE1↓, 1,   E2Fs↓, 2,   E2Fs↑, 1,   GADD45A↓, 1,   Ki-67↓, 19,   mitA↑, 1,   P21↓, 6,   P21↑, 42,   p27/CDKN1B↓, 3,   p27/CDKN1B↑, 23,   pRB↓, 2,   pRB↑, 1,   p‑pRB↓, 7,   RB1↓, 1,   RB1↑, 3,   p‑RB1↓, 4,   Securin↓, 2,   TumCCA↓, 5,   TumCCA↑, 110,   WEE1↑, 1,  

Proliferation, Differentiation & Cell State(tgid=12) ⓘ

4E-BP1↓, 1,   p‑4E-BP1↓, 3,   ALDH1A1↓, 3,   BMP2↓, 1,   BMPs↑, 2,   CD133↓, 7,   CD24↓, 3,   cFos↓, 6,   p‑cFos↓, 1,   cMYB↓, 2,   CSCs?, 1,   CSCs↓, 14,   Diff↓, 1,   Diff↑, 3,   FGF↓, 2,   Gli1↓, 1,   GREM1↓, 1,   HH↓, 1,   IGF-1↓, 10,   IGFBP3↑, 4,   JAG1↓, 1,   Jun↓, 1,   p‑Jun↑, 1,   Ki-67↓, 19,   Let-7↑, 2,   LGR5↓, 1,   Mel↓, 1,   mTORC1↓, 4,   p‑mTORC1↓, 1,   Nanog↓, 5,   Nestin↓, 3,   NICD↓, 1,   NOTCH↓, 11,   NOTCH1↓, 6,   NOTCH1↑, 1,   Piezo1↑, 1,   Shh↓, 3,   Smo↓, 1,   TAZ↓, 1,   TumCG↓, 54,   TumCP?, 1,   TumCP↓, 105,   TumCP↑, 1,   TumCP∅, 1,   tyrosinase↓, 1,   Wnt↓, 31,   Wnt/(β-catenin)↓, 9,   ZFX↓, 1,  

Migration(tgid=13) ⓘ

AEG1↓, 1,   AntiAg↓, 1,   AntiAg↑, 1,   AP-1↓, 14,   AP-1↑, 2,   BACH1↓, 1,   CA↓, 1,   Ca+2↓, 2,   Ca+2↑, 21,   Ca+2↝, 1,   mt-Ca+2↑, 1,   cal2↓, 1,   cal2↑, 1,   Cdc42↓, 1,   Cdc42↑, 1,   Cofilin↓, 1,   DLC1↑, 1,   E-cadherin↓, 3,   E-cadherin↑, 28,   EM↑, 1,   EMMPRIN↓, 1,   EMT↓, 43,   EMT↑, 3,   F-actin↓, 1,   FAK↓, 17,   p‑FAK↓, 5,   p‑FAK↑, 1,   fascin↓, 2,   Fibronectin↓, 3,   Furin↓, 1,   IQGAP3↓, 1,   ITGA5↓, 3,   ITGB1↓, 4,   ITGB1↑, 1,   ITGB4↓, 1,   ITGB6↓, 1,   KRAS↓, 3,   LAMs↓, 2,   MET↓, 2,   MMP-10↓, 3,   MMP1↓, 8,   MMP13↓, 2,   MMP16↓, 1,   MMP2↓, 73,   MMP3↓, 4,   MMP7↓, 9,   MMP9↓, 86,   pro‑MMP9↓, 1,   MMP9:TIMP1↓, 1,   MMPs↓, 18,   MUC1↓, 1,   N-cadherin↓, 20,   NCAM↑, 1,   NFAT↑, 1,   pax↓, 1,   p‑pax↓, 1,   PDGF↓, 5,   Rac1↓, 2,   Rho↓, 5,   Rho↑, 1,   ROCK1↓, 2,   ROCK1↑, 2,   Sharpin↓, 1,   Slug↓, 9,   Smad1↑, 1,   Smad1↝, 1,   p‑SMAD2↓, 3,   SMAD3↓, 2,   p‑SMAD3↓, 2,   SMAD4↓, 2,   Snail↓, 15,   TET1↓, 1,   TET1↑, 1,   TGF-β↓, 13,   TGF-β↝, 1,   TGF-β1↓, 1,   TIMP1↓, 1,   TIMP1↑, 7,   TIMP2↓, 2,   TIMP2↑, 7,   TIMP3↑, 1,   TSC1↑, 1,   TSP-1↑, 3,   TumCA↓, 2,   TumCI↓, 58,   TumCI↑, 1,   TumCMig↓, 67,   TumCMig↑, 2,   TumMeta↓, 44,   TumMeta↑, 1,   Twist↓, 18,   uPA↓, 20,   uPAR↓, 2,   Vim↓, 24,   Zeb1↓, 6,   ZEB2↓, 2,   β-catenin/ZEB1↓, 38,  

Angiogenesis & Vasculature(tgid=14) ⓘ

angioG↓, 52,   angioG↑, 3,   angioS↑, 1,   CD31/PECAM-1↓, 2,   ECM/TCF↓, 1,   EGR1↑, 1,   Endoglin↑, 1,   HIF-1↓, 5,   Hif1a↓, 39,   Hif1a↝, 1,   LOX1↓, 1,   NO↓, 5,   NO↑, 3,   PHDs↓, 1,   VCAM-1↓, 2,   VEGF↓, 77,   VEGFR1↓, 1,   VEGFR2/KDR/Flk1↓, 15,  

Barriers & Transport(tgid=15) ⓘ

BBB↑, 2,   CellMemb↑, 1,   CLDN1↓, 1,   CLDN1↑, 1,   CLDN2↓, 1,   CTR1↑, 1,   EPR↑, 2,   GLUT1↓, 5,   GLUT4↓, 1,   IBI↑, 1,   memfluid↓, 1,   MMP↓, 82,   MMP↑, 1,   MPT↑, 2,   NHE1↓, 2,   OCLN↑, 1,   TJ↑, 1,   TRPM7↓, 1,   ZO-1↑, 2,  

Immune & Inflammatory Signaling(tgid=16) ⓘ

CB2 / CNR2↑, 1,   CCR7↓, 1,   CD25+↑, 1,   CD4+↓, 1,   CD4+↑, 1,   CD44↓, 9,   p‑cDC2↓, 1,   COX1↓, 1,   COX2/PTGS2↓, 60,   COX2/PTGS2↑, 3,   CXCL1↓, 1,   CXCL12↓, 1,   CXCR4↓, 12,   DR4↑, 5,   FOXP3↑, 1,   HMGB1↓, 2,   ICAM-1↓, 1,   IFN-γ↓, 5,   IFN-γ↑, 4,   IL1↓, 7,   IL1↑, 1,   IL10↓, 6,   IL10↑, 2,   IL12↓, 1,   IL17↓, 1,   IL18↓, 1,   IL1α↓, 2,   IL1β↓, 14,   IL1β↑, 1,   IL2↓, 1,   IL2↑, 5,   IL22↓, 1,   IL23↓, 1,   IL4↓, 1,   IL4↑, 2,   IL6↓, 31,   IL6↑, 1,   IL8↓, 7,   IL8↑, 1,   Imm↑, 5,   Imm↝, 2,   Inflam↓, 27,   M2 MC↓, 1,   MCP1/CCL2↓, 6,   MDSCs↓, 1,   MIP2↓, 3,   NF-kB?, 1,   NF-kB↓, 112,   NF-kB↑, 4,   NF-kB↝, 3,   p‑NF-kB↑, 2,   NK cell↑, 5,   NLRP3↓, 1,   NLRP3↑, 1,   p50↓, 1,   p65↓, 8,   PD-1↓, 1,   PD-L1↓, 6,   PGD2↓, 1,   PGE2↓, 20,   PSA↓, 7,   SOCS1↑, 1,   T-Cell↑, 2,   TCF↓, 1,   TCF↑, 1,   TLR1↑, 1,   TLR2↑, 1,   TLR4↓, 3,   TLR4↑, 1,   TLR4↝, 1,   TNF-α↓, 30,   TNF-α↑, 1,   TNFRSF25/DR3/APO3/LARD/TRAMP/WSL1↑, 1,  

Cellular Microenvironment(tgid=17) ⓘ

ADAM17↓, 1,   IM↓, 1,   TAMS↝, 1,  

Synaptic & Neurotransmission(tgid=18) ⓘ

5HT↓, 1,   PTN↓, 1,  

Protein Aggregation(tgid=19) ⓘ

PSEN1/PS1↓, 1,   PSEN2/PS-2↓, 1,  

Hormonal & Nuclear Receptors(tgid=20) ⓘ

AR↓, 13,   COMT↓, 2,   ER-α36↓, 1,   ERα/ESR1↓, 1,   PPARα↓, 2,   PPARγ↑, 3,  

Drug Metabolism & Resistance(tgid=21) ⓘ

ABCG2↓, 3,   BioAv↓, 24,   BioAv↑, 22,   BioAv↝, 4,   BioEnh↑, 1,   chemoR↓, 1,   ChemoSen↓, 2,   ChemoSen↑, 87,   CompStab↓, 1,   CompStab↑, 1,   CompStab↝, 1,   CYP1A1↓, 3,   CYP1A1↑, 2,   CYP1A2↓, 1,   CYP1A2↑, 1,   CYP1B1↑, 1,   CYP2A3/CYP2A6↓, 1,   CYP2E1↑, 1,   CYP3A4↓, 2,   Dose?, 4,   Dose↓, 3,   Dose↑, 5,   Dose↝, 26,   Dose∅, 11,   eff?, 1,   eff↓, 26,   eff↑, 43,   eff↝, 8,   eff∅, 1,   GSTA1↑, 1,   Half-Life↓, 4,   Half-Life↑, 1,   Half-Life↝, 9,   Half-Life∅, 1,   MDR1↓, 3,   MRP1/ABCC1↓, 2,   P-gp/ABCB1↓, 10,   P-gp/ABCB1↝, 1,   P450↓, 2,   RadioS↑, 31,   selectivity?, 2,   selectivity↑, 48,   Synergy↑, 58,   TET2↑, 1,  

Clinical Biomarkers(tgid=22) ⓘ

AFP↓, 1,   ALAT↓, 4,   ALAT↝, 1,   ALP↓, 2,   ALP↝, 1,   AR↓, 13,   ascitic↓, 1,   AST↓, 2,   AST↝, 1,   BMD↑, 1,   BRAF↓, 1,   BRAF↝, 1,   BRCA1↓, 2,   BRCA1↑, 1,   p‑BRCA1↑, 1,   CRP↓, 2,   E6↓, 3,   E7↓, 3,   EGFR↓, 49,   p‑EGFR↓, 4,   ERα/ESR1↓, 1,   EZH2↓, 1,   FOXM1↓, 3,   HER2/EBBR2↓, 9,   p‑HER2/EBBR2↓, 1,   hTERT/TERT↓, 9,   IL6↓, 31,   IL6↑, 1,   KRAS↓, 3,   LDH↓, 3,   LDH↑, 1,   Maspin↑, 1,   Myc↓, 4,   PD-L1↓, 6,   PSA↓, 7,   TP53↑, 2,  

Functional Outcomes(tgid=23) ⓘ

AntiCan↑, 32,   AntiCan∅, 1,   antiD↑, 1,   antiNeop↑, 4,   AntiTum↓, 1,   AntiTum↑, 12,   cachexia↓, 1,   cardioP↑, 9,   chemoP↓, 1,   chemoP↑, 22,   chemoPv↑, 10,   ChemoSideEff↓, 7,   ChemoSideEff∅, 1,   cognitive?, 1,   hepatoP↑, 9,   neuroP↑, 5,   NP/CIPN↓, 1,   OS↑, 7,   Pain↓, 1,   QoL↑, 2,   radioP↑, 7,   Remission↑, 1,   RenoP↑, 5,   Risk↓, 8,   toxicity↓, 8,   toxicity↝, 2,   toxicity∅, 4,   TumVol↓, 13,   TumW↓, 7,   Weight∅, 1,  

Infection & Microbiome(tgid=24) ⓘ

AntiBio↓, 1,   AntiP↑, 1,   Bacteria↓, 1,   GutMicro↑, 5,   Sepsis↓, 1,  

Ingredients & Constituents(tgid=25) ⓘ

Ingr?, 1,   Ingr↝, 2,  
Total Targets: 937

Pathway results for Effect on Normal Cells:


NA, unassigned(tgid=0) ⓘ

NA↓, 1,  

Redox & Oxidative Stress(tgid=1) ⓘ

antiOx?, 2,   antiOx↓, 2,   antiOx↑, 62,   ARE↓, 1,   ARE↑, 1,   Catalase↑, 31,   GCLC↑, 2,   GCLM↑, 2,   GPx↑, 20,   GPx1↑, 1,   GPx4↑, 3,   GSH↓, 1,   GSH↑, 32,   GSR↑, 4,   GSSG↓, 1,   GSTs↑, 10,   H2O2↓, 2,   H2O2↑, 1,   H2O2∅, 1,   HDL↓, 1,   HDL↑, 2,   HO-1↓, 3,   HO-1↑, 31,   Iron↓, 2,   i-Iron↓, 1,   Keap1↓, 4,   Keap1↑, 1,   Keap1↝, 1,   lipid-P?, 1,   lipid-P↓, 15,   MDA↓, 19,   MDA↑, 1,   MPO↓, 3,   NADH↓, 1,   NOX4↓, 1,   NQO1↑, 2,   Nrf1↑, 1,   NRF2↓, 1,   NRF2↑, 43,   Prx↑, 1,   RNS↓, 3,   ROS?, 1,   ROS↓, 79,   ROS↑, 1,   ROS⇅, 1,   mt-ROS?, 1,   mt-ROS↓, 1,   SOD↑, 39,   SOD1↑, 3,   SOD2↑, 1,   TAC↑, 2,   Trx↑, 1,   Trx1↑, 1,   uricA↓, 1,   VitC↑, 1,   xCT/SLC7A11↑, 1,  

Metal & Cofactor Biology(tgid=2) ⓘ

FTL↓, 1,   IronCh↑, 4,   IronCh↝, 1,   TfR1/CD71↓, 1,  

Mitochondria & Bioenergetics(tgid=3) ⓘ

compI↑, 1,   compIII↑, 1,   compV↑, 1,   DRP1/DNM1L↓, 1,   p‑DRP1/DNM1L↝, 1,   Insulin↑, 1,   MFN1↝, 1,   MFN2↑, 1,   MFN2↝, 1,   PGC-1α↑, 3,   PGC-1α↝, 1,   SIRT3↑, 2,  

Core Metabolism/Glycolysis(tgid=4) ⓘ

12LOX↓, 3,   5LO↓, 5,   ACSL4↓, 1,   adiP↑, 1,   ALAT↓, 6,   AMPK↓, 1,   AMPK↑, 7,   p‑AMPK↑, 1,   ATP↑, 4,   Buty↑, 1,   cAMP↑, 3,   CRM↑, 1,   glucose↓, 1,   glucose↑, 1,   glucose↝, 2,   GlucoseCon↑, 2,   Glycolysis↑, 1,   GSK‐3β↓, 6,   GSK‐3β↑, 2,   p‑GSK‐3β↑, 2,   HMG-CoA↓, 1,   LDL↓, 3,   lipidLev↓, 1,   NADPH↓, 2,   SCFAs↑, 1,   SIRT1↑, 3,  

Cell Death(tgid=5) ⓘ

AIF↓, 1,   APAF1↓, 1,   Apoptosis↓, 8,   BAD↓, 1,   BAX↓, 3,   Bcl-2↑, 2,   Bcl-xL↑, 1,   Casp3↓, 12,   Casp3∅, 1,   Casp6↓, 1,   Casp9↓, 4,   Casp9∅, 1,   Cyt‑c∅, 2,   Fas↓, 1,   Ferroptosis↓, 3,   iNOS↓, 14,   iNOS↑, 2,   necrosis↓, 2,   p38↓, 8,   p38↑, 2,   p‑p38↓, 5,  

Kinase & Signal Transduction(tgid=6) ⓘ

Akt↓, 3,   Akt↑, 18,   p‑Akt↓, 1,   p‑Akt↑, 5,   e-Akt↑, 1,   Akt2↓, 1,   AMPKα↑, 1,   CREB↓, 1,   CREB↑, 8,   p‑CREB↑, 4,   EGFR↓, 1,   ERK↓, 29,   ERK↑, 31,   p‑ERK↓, 11,   p‑ERK↑, 11,   e-ERK↑, 1,   HGF/c-Met↑, 1,   IKKα↓, 2,   IKKα↑, 1,   p‑IKKα↓, 3,   IκB↓, 1,   p‑IκB↓, 1,   JAK2↓, 1,   JNK↓, 10,   JNK↑, 1,   p‑JNK↓, 5,   p‑JNK↑, 2,   MAPK↓, 17,   MAPK↑, 7,   p‑MAPK↓, 1,   p‑MEK↓, 1,   p‑MEK↑, 1,   mTOR↓, 2,   mTOR↑, 4,   P70S6K↓, 1,   p‑P70S6K↑, 1,   PI3K↓, 3,   PI3K↑, 11,   p‑PI3K↑, 1,   PKA↑, 3,   PKCδ↓, 2,   PKCδ↑, 2,   PP2A↑, 1,   PTEN↓, 2,   PTEN↑, 1,   Raf↓, 1,   STAT3↓, 4,   STAT3↑, 1,   p‑STAT3↑, 1,   STAT4↓, 1,   STAT5↓, 1,  

Transcription & Epigenetics(tgid=7) ⓘ

AntiThr↑, 1,   ATF2↑, 1,   p‑cJun↓, 1,   p‑cMyc↑, 1,   FOXO1↝, 1,   FOXO3↑, 1,   ac‑H3↑, 1,   ac‑H4↑, 1,   HDAC↓, 1,   HDAC2↓, 1,   HOTAIR↑, 1,   other↓, 3,   other↑, 2,   other↝, 8,   tumCV∅, 1,  

Protein Folding & ER Stress(tgid=8) ⓘ

CHOP/DDIT3↓, 1,   CHOP/DDIT3↑, 1,   GRP78/BiP↓, 1,   GRP78/BiP↑, 1,   GRP94↑, 1,   HSP70/HSPA5↓, 1,   HSP70/HSPA5↑, 2,   HSP90↑, 1,  

Autophagy & Lysosomes(tgid=9) ⓘ

Beclin-1/ATG6↓, 1,   Beclin-1/ATG6↑, 1,   LC3II↑, 1,   p62↑, 1,  

DNA Damage & Repair(tgid=10) ⓘ

DNAdam↓, 4,   P53↓, 1,   PARP∅, 1,   PARP1↓, 1,   PCNA↓, 1,  

Cell Cycle & Senescence(tgid=11) ⓘ

CDK2↓, 1,   CDK4↓, 1,   CDK5↓, 1,   cycD1/CCND1↓, 1,   cycE/CCNE↓, 1,   P21↓, 1,   RB1↓, 1,  

Proliferation, Differentiation & Cell State(tgid=12) ⓘ

BMP2↑, 1,   Diff↑, 1,   Diff↝, 1,   HH↓, 1,   IGF-1↑, 1,   neuroG↑, 1,   STAT1↓, 1,  

Migration(tgid=13) ⓘ

AntiAg↑, 8,   AP-1↓, 2,   ARG1/2↑, 1,   Ca+2↓, 4,   Ca+2↝, 1,   p‑Cofilin↓, 1,   COL1↓, 2,   E-cadherin↑, 1,   EMT↓, 1,   Fibrosis↓, 1,   heparanase↑, 1,   MLC2/MYL9↝, 1,   MMP13↓, 2,   MMP3↓, 1,   MMP9↓, 4,   N-cadherin↑, 1,   p‑Rac1↓, 1,   Rho↓, 2,   ROCK1↓, 1,   p‑Smad1↑, 1,   SMAD2↓, 1,   SMAD3↓, 1,   p‑SMAD5↑, 1,   p‑T-cadherin↓, 1,   TGF-β1↓, 2,   TGF-β1↑, 1,   TIMP1↓, 1,   TregCell↑, 1,   Vim↓, 1,   α-SMA↓, 5,   β-catenin/ZEB1↑, 1,  

Angiogenesis & Vasculature(tgid=14) ⓘ

angioG↓, 1,   angioG↑, 2,   CD31/PECAM-1↓, 1,   CD31/PECAM-1↑, 1,   E-sel↓, 1,   eNOS↑, 2,   HIF-1↓, 1,   NO↓, 9,   NO↑, 2,   VCAM-1↓, 8,   VEGF↓, 1,   VEGF↑, 3,  

Barriers & Transport(tgid=15) ⓘ

BBB?, 1,   BBB↑, 11,   BBB↝, 2,   CLDN4↑, 1,   GastroP↑, 1,   GLUT1↑, 1,   GLUT2↑, 1,   GLUT4↑, 3,   H+/K+-ATPase↓, 1,   IBI↑, 2,   MMP↑, 8,   MUC19↓, 1,   MUC2↓, 1,   MUC5AC↓, 1,   OCLN↑, 2,   OCLN↝, 1,   TJ↑, 3,   TRPM7↓, 1,   ZO-1↑, 2,  

Immune & Inflammatory Signaling(tgid=16) ⓘ

CB2 / CNR2↑, 1,   CCL11↓, 1,   CD25+↓, 1,   CD69↓, 1,   COX1↓, 3,   COX2/PTGS2↓, 20,   COX2/PTGS2↑, 1,   CTLA-4↓, 1,   Eos↓, 1,   HMGB1↓, 2,   ICAM-1↓, 4,   IFN-γ↓, 3,   IL1↓, 2,   IL10↓, 2,   IL10↑, 2,   IL17↓, 3,   IL18↓, 1,   IL1β↓, 20,   IL2↓, 2,   IL2↑, 1,   IL23↓, 1,   IL4↓, 3,   IL4↑, 1,   IL6?, 1,   IL6↓, 22,   IL8↓, 3,   Imm↑, 7,   Imm⇅, 1,   Inflam↓, 78,   pol-M2 MC↑, 1,   Macrophages↓, 1,   MCP1/CCL2↓, 2,   MyD88↓, 1,   Neut↓, 1,   NF-kB↓, 41,   p‑NF-kB↓, 3,   NLRP3↓, 4,   p‑p50↓, 1,   p65↓, 1,   p‑p65↓, 2,   PGE2↓, 5,   PGE2↑, 1,   RAGE↓, 2,   Th1 response↓, 2,   Th17↓, 1,   Th2↑, 2,   TLR2↓, 1,   TLR4↓, 7,   TNF-α↓, 27,  

Synaptic & Neurotransmission(tgid=18) ⓘ

5HT↓, 1,   5HT↑, 1,   AChE↓, 11,   ADAM10↑, 1,   BChE↓, 3,   BDNF↑, 12,   BDNF∅, 1,   GABA↑, 1,   NGF↑, 1,   PSD95↑, 1,   TPH1↓, 1,   TrkB↑, 3,  

Protein Aggregation(tgid=19) ⓘ

AGEs↓, 2,   APP↓, 4,   Aβ↓, 16,   Aβ↑, 1,   BACE/β-secretase↓, 3,   IDE↑, 1,   tau↓, 3,   p‑tau↓, 4,   XO↝, 1,  

Hormonal & Nuclear Receptors(tgid=20) ⓘ

ACE/ACE1↓, 1,   ACE2↓, 1,   ERβ/ESR2↑, 1,   Estro↓, 1,   GLP-1R↑, 1,   NR1H4↑, 1,   PPARα↑, 1,   PPARγ↓, 1,   PPARγ↑, 3,  

Drug Metabolism & Resistance(tgid=21) ⓘ

BioAv↓, 16,   BioAv↑, 27,   BioAv↝, 18,   BioEnh↑, 3,   Dose?, 1,   Dose↑, 1,   Dose↝, 7,   eff↓, 2,   eff↑, 9,   GSTA1↑, 2,   Half-Life↓, 1,   Half-Life↑, 2,   Half-Life↝, 6,   P-gp/ABCB1↓, 1,   Synergy↑, 3,  

Clinical Biomarkers(tgid=22) ⓘ

ALAT↓, 6,   ALP↓, 2,   AST↓, 8,   BloodF↑, 1,   BMD↑, 2,   BP↓, 4,   BP↝, 1,   creat↓, 2,   CRP↓, 2,   EGFR↓, 1,   hs-CRP↓, 1,   IL6?, 1,   IL6↓, 22,   IRes↝, 1,   LDH↓, 3,   LDH↑, 1,   NOS2↓, 1,   RAGE↓, 2,   Urea↓, 1,  

Functional Outcomes(tgid=23) ⓘ

Analgesic↑, 2,   AntiAge↑, 1,   antiAll↑, 9,   AntiArt↑, 4,   AntiCan↑, 12,   AntiDiabetic↓, 1,   AntiDiabetic↑, 15,   antiPs↑, 1,   AntiTum↑, 3,   cardioP↑, 20,   CardioT↓, 1,   chemoP↑, 5,   chemoPv↑, 3,   cognitive↓, 1,   cognitive↑, 21,   diuretic↑, 2,   hepatoP↓, 1,   hepatoP↑, 20,   Learn↑, 1,   memory↑, 19,   motorD↑, 3,   Mucositis↓, 1,   neuroP?, 1,   neuroP↑, 55,   Obesity↓, 6,   Pain↓, 3,   radioP↑, 1,   RenoP↑, 8,   Strength↑, 1,   Stroke↓, 3,   toxicity↓, 12,   toxicity↑, 1,   toxicity↝, 2,   toxicity∅, 3,   Wound Healing↑, 2,  

Infection & Microbiome(tgid=24) ⓘ

AntiFungal↑, 1,   AntiP↑, 1,   AntiViral↑, 8,   Bacteria↓, 13,   Diar↓, 1,   GutMicro↑, 9,   Inf↓, 1,  

Ingredients & Constituents(tgid=25) ⓘ

Ingr↑, 1,   Ingr↝, 6,  
Total Targets: 436

Scientific Paper Hit Count for: ERK, ERK signaling
16 Berberine
16 Curcumin
15 Fisetin
15 Quercetin
13 Sulforaphane (mainly Broccoli)
12 Silymarin (Milk Thistle) silibinin
11 Shikonin
10 EGCG (Epigallocatechin Gallate)
10 Magnetic Fields
9 Apigenin (mainly Parsley)
9 Kaempferol
9 Thymoquinone
8 Luteolin
8 Baicalein
7 Artemisinin
7 Caffeic acid
7 Formononetin
6 Radiotherapy/Radiation
6 Propolis -bee glue
6 Honokiol
6 Isobavachalcone
6 Morin
6 Licochalcone A
6 Lycopene
5 Alpha-Lipoic-Acid
5 Chrysin
5 Piperine
5 Resveratrol
4 Silver-NanoParticles
4 Allicin (mainly Garlic)
4 Astaxanthin
4 Carvacrol
4 Emodin
4 Fucoidan
4 Garcinol
4 phytic acid, Inositol hexakisphosphate
4 isoorientin
4 Magnolol
4 Matrine
4 Rosmarinic acid
4 Vitamin K2
3 Cisplatin
3 Berbamine
3 Boswellia (frankincense)
3 Chlorogenic acid
3 Cynaropicrin
3 Paclitaxel/Taxol
3 Ferulic acid
3 Hyperoside
3 Inositol
3 methylseleninic acid
3 Phenethyl isothiocyanate
3 Piperlongumine
3 Ursolic acid
3 Vitamin C (Ascorbic Acid)
2 Andrographis
2 Ashwagandha(Withaferin A)
2 beta-glucans
2 Beta-Caryophyllene
2 Betulinic acid
2 Bromelain
2 Boron
2 Zinc
2 Capsaicin
2 Thymol-Thymus vulgaris
2 chaetocin
2 Crocetin
2 Cucurbitacin
2 Deguelin
2 Dandelion Root
2 Flaxseed/Linseed
2 5-fluorouracil
2 Gambogic Acid
2 Geraniol
2 Ginger/6-Shogaol/Gingerol
2 Ginkgetin
2 isoquercitrin
2 Licorice
2 Lutein
2 Magnetic Field Rotating
2 Myricetin
2 Nimbolide
2 Phenylbutyrate
2 Pterostilbene
2 Sanguinarine
2 Salvia miltiorrhiza
2 Urolithin
2 Vitexin
1 1,8-Cineole
1 Camptothecin
1 alpha Linolenic acid
1 Anethole/trans-Anethole
1 Ascorbyl Palmitate
1 Trastuzumab
1 Baicalin
1 Biochanin A
1 Bacopa monnieri
1 brusatol
1 α-Bisabolol / Chamomile oil
1 Centella asiatica / Gotu kola → asiaticoside
1 Chlorophyllin
1 Cinnamon
1 Citric Acid
1 Coenzyme Q10
1 Vitamin E
1 Copper and Cu NanoParticles
1 Dihydrocaffeic Acid
1 Photodynamic Therapy
1 Bicalutamide
1 gefitinib, erlotinib
1 Docosahexaenoic Acid
1 Dipyridamole
1 Ellagic acid
1 Ginkgo biloba-EGb 761
1 eicosapentaenoic acid
1 Evodiamine
1 flavonoids
1 Metformin
1 Gallic acid
1 Ginkgo biloba
1 Genistein (soy isoflavone)
1 Ginseng
1 Graviola
1 Grapeseed extract
1 Hydrogen Gas
1 epipolythiodioxopiperazine / epipolythiopiperazine-2,5-dione
1 Huperzine A/Huperzia serrata
1 Isoliquiritigenin
1 Juglone
1 Mung Bean Sprouts
1 Lasiodin
1 Lemongrass Extract/Citral
1 SDG/lignans
1 Linalool
1 mebendazole
1 Methyl Jasmonate
1 vp16, etoposide
1 Methyl salicylate / Sweet Birch oil
1 Magnesium
1 Melatonin
1 Moringa oleifera
1 Naringin
1 Niclosamide (Niclocide)
1 Oleocanthal
1 Oxygen, Hyperbaric
1 SonoDynamic Therapy UltraSound
1 Hyperthermia
1 Plumbagin
1 Salvia officinalis
1 Aromatherapy
1 Aflavin-3,3′-digallate
1 Tomatine
1 Turmerones
1 Isovitexin
Query results interpretion may depend on "conditions" listed in the research papers.
Such Conditions may include : 
  -low or high Dose
  -format for product, such as nano of lipid formations
  -different cell line effects
  -synergies with other products 
  -if effect was for normal or cancerous cells

Filter Conditions: Pro/AntiFlg:%  IllCat:%  CanType:%  Cells:%  prod#:%  Target#:105  State#:%  Dir#:%
  wNotes=0  sortOrder:rid,rpid

 

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