| Source: HalifaxProj (block) |
| Type: |
| Tumor Necrosis Factor-alpha (TNF-α) is a cytokine that plays a complex role in cancer biology. It is primarily produced by activated macrophages and is involved in systemic inflammation.
TNF-α is a pro-inflammatory cytokine that can promote inflammation, which is a known factor in cancer development. Overall, the expression of TNF-α in cancers is often linked to inflammation, tumor progression, and the tumor microenvironment. |
| 7040- | GA, | Effects of gallic acid on acrylamide-induced endoplasmic reticulum stress, neuroinflammation and neuronal apoptosis in rats |
| - | Trial, | AD, | NA |
| 7028- | GA, | Gallic acid: Pharmacological activities and molecular mechanisms involved in inflammation-related diseases |
| - | Review, | Nor, | NA |
| 7080- | GABA, | The Effect of Oral GABA on the Nervous System: Potential for Therapeutic Intervention |
| - | Review, | AD, | NA |
| 7052- | Gallo, | Galloflavin Relieves the Malignant Behavior of Colorectal Cancer Cells in the Inflammatory Tumor Microenvironment |
| - | in-vivo, | Colon, | SW48 |
| 7066- | GamB, | Unravelling the Therapeutic Potential of Gambogic Acid: Deciphering Its Molecular Mechanism of Action and Emerging Role as an Anticancer Xanthone |
| - | Review, | Var, | NA |
| 7067- | GamB, | Gambogic Acid and Its Role in Chronic Diseases |
| - | Review, | Var, | NA |
| 7086- | GAR, | Garcinol: An emerging epigenetic modifier with versatile anticancer properties |
| - | Review, | Var, | NA |
| - | in-vitro, | Nor, | RAW264.7 |
| 3723- | GBE, | Can We Use Ginkgo biloba Extract to Treat Alzheimer’s Disease? Lessons from Preclinical and Clinical Studies |
| - | Review, | AD, | NA |
| 7212- | GBE, | The Use of Ginkgo Biloba L. as a Neuroprotective Agent in the Alzheimer’s Disease |
| - | Review, | AD, | NA |
| 7126- | Ge-132, | Immune activation of Bio-Germanium in a randomized, double-blind, placebo-controlled clinical trial with 130 human subjects: Therapeutic opportunities from new insights |
| - | Trial, | Nor, | NA |
| 6570- | Ger, | Apoptosis-Mediated Anticancer Activity of Geraniol Inhibits NF-κB, MAPK, and JAK-STAT-3 Signaling Pathways in Human Thyroid Cancer Cells |
| - | in-vitro, | Thyroid, | TPC-1 |
| 7137- | GI, | 6-Shogaol from dried ginger inhibits growth of prostate cancer cells both in vitro and in vivo through inhibition of STAT3 and NF-κB signaling |
| - | in-vitro, | Pca, | LNCaP | - | in-vitro, | Pca, | DU145 | - | in-vitro, | Pca, | PC3 | - | vitro+vivo, | Pca, | HMVP2 |
| 7140- | GI, | Benefits of Ginger and Its Constituent 6-Shogaol in Inhibiting Inflammatory Processes |
| - | Review, | Var, | NA |
| 4003- | Gins, | Neuroprotective Potentials of Panax Ginseng Against Alzheimer's Disease: A Review of Preclinical and Clinical Evidences |
| - | Review, | adrenal, | NA |
| 4511- | GLA, | Gamma-Linolenic Acid (GLA) Protects against Ionizing Radiation-Induced Damage: An In Vitro and In Vivo Study |
| - | vitro+vivo, | Nor, | RAW264.7 |
| 7325- | GSE, | The Effects of a Grape Seed Procyanidin Extract on Cytochrome P450 3A4 Activity and Inflammatory Mediators in the Lungs of Heavy Active and Former Smokers |
| - | in-vitro, | Lung, | NA |
| 4346- | H2, | Medical Application of Hydrogen in Hematological Diseases |
| - | Review, | NA, | NA |
| 4307- | H2, | Hydrogen Gas Attenuates Toxic Metabolites and Oxidative Stress-Mediated Signaling to Inhibit Neurodegeneration and Enhance Memory in Alzheimer’s Disease Models |
| - | in-vivo, | AD, | NA |
| 7925- | H2, | Inhalation of hydrogen gas attenuates airway inflammation and oxidative stress in allergic asthmatic mice |
| - | in-vivo, | Asthma, | NA |
| 7929- | H2, | Hydrogen-rich saline reduces airway remodeling via inactivation of NF-κB in a murine model of asthma |
| - | NA, | Asthma, | NA |
| 7487- | H2, | A comprehensive review of molecular hydrogen as a novel nutrition therapy in relieving oxidative stress and diseases: Mechanisms and perspectives |
| - | Review, | Nor, | NA |
| 7489- | H2, | Molecular Hydrogen in the Treatment of Respiratory Diseases |
| - | Review, | Asthma, | NA |
| 7492- | H2, | Chemo, | Molecular Hydrogen Protects against Various Tissue Injuries from Side Effects of Anticancer Drugs by Reducing Oxidative Stress and Inflammation |
| - | Review, | Var, | NA |
| 7482- | H2, | Molecular Hydrogen Therapy: Mechanisms, Delivery Methods, Preventive, and Therapeutic Application |
| - | Review, | Var, | NA | - | Review, | IBD, | NA | - | Review, | Stroke, | NA | - | Review, | Sepsis, | NA | - | Review, | AD, | NA |
| 7483- | H2, | Cisplatin, | Molecular hydrogen attenuates cisplatin-induced nephrotoxicity by modulating β-hydroxybutyrate metabolism |
| - | in-vivo, | Nor, | HK-2 |
| 7484- | H2, | Hydrogen Gas Attenuates Toxic Metabolites and Oxidative Stress-Mediated Signaling to Inhibit Neurodegeneration and Enhance Memory in Alzheimer's Disease Models |
| - | in-vivo, | AD, | NA |
| 2523- | H2, | Prospects of molecular hydrogen in cancer prevention and treatment |
| - | Review, | Var, | NA |
| 2521- | H2, | Oxyhydrogen Gas: A Promising Therapeutic Approach for Lung, Breast and Colorectal Cancer |
| - | Review, | CRC, | NA | - | Review, | Lung, | NA | - | Review, | BC, | NA |
| 2516- | H2, | Hydrogen Gas in Cancer Treatment |
| - | Review, | Var, | NA |
| 2514- | H2, | Hydrogen: A Novel Option in Human Disease Treatment |
| - | Review, | NA, | NA |
| 2503- | H2, | Brain Metastases Completely Disappear in Non-Small Cell Lung Cancer Using Hydrogen Gas Inhalation: A Case Report |
| - | Case Report, | Lung, | NA |
| 3770- | H2, | Role of Molecular Hydrogen in Ageing and Ageing-Related Diseases |
| - | Review, | AD, | NA | - | Review, | Park, | NA |
| 3772- | H2, | Therapeutic potential of hydrogen-rich water in zebrafish model of Alzheimer’s disease: targeting oxidative stress, inflammation, and the gut-brain axis |
| - | in-vivo, | AD, | NA |
| 3773- | H2, | Role and mechanism of molecular hydrogen in the treatment of Parkinson’s diseases |
| - | Review, | Park, | NA |
| 3787- | H2, | Hydrogen, a Novel Therapeutic Molecule, Regulates Oxidative Stress, Inflammation, and Apoptosis |
| - | Review, | AD, | NA |
| 3764- | H2, | Therapeutic Effects of Hydrogen Gas Inhalation on Trimethyltin-Induced Neurotoxicity and Cognitive Impairment in the C57BL/6 Mice Model |
| - | in-vivo, | AD, | NA |
| 3766- | H2, | The role of hydrogen in Alzheimer′s disease |
| - | Review, | AD, | NA |
| 7499- | H2S, | Hydrogen sulfide slows down progression of experimental Alzheimer's disease by targeting multiple pathophysiological mechanisms |
| 1637- | HCA, | OLST, | Orlistat and Hydroxycitrate Ameliorate Colon Cancer in Rats: The Impact of Inflammatory Mediators |
| - | in-vivo, | Colon, | NA |
| 7365- | HibSad, | Insight into the molecular evidence supporting the remarkable chemotherapeutic potential of Hibiscus sabdariffa L |
| - | Review, | Var, | NA |
| 7468- | HNK, | Honokiol and Its Emerging Role in Breast Cancer Therapy |
| - | Review, | BC, | NA |
| 7455- | HNK, | Honokiol in cancer: Roles in enhancing combination therapy efficacy and preventing post-transplant malignancies |
| - | Review, | Var, | NA |
| 2883- | HNK, | Honokiol targets mitochondria to halt cancer progression and metastasis |
| - | Review, | Var, | NA |
| 2871- | HNK, | Antihyperalgesic Properties of Honokiol in Inflammatory Pain Models by Targeting of NF-κB and Nrf2 Signaling |
| - | in-vivo, | Nor, | NA |
| 2869- | HNK, | Nature's neuroprotector: Honokiol and its promise for Alzheimer's and Parkinson's |
| - | Review, | AD, | NA | - | Review, | Park, | NA |
| 2868- | HNK, | Honokiol: A review of its pharmacological potential and therapeutic insights |
| - | Review, | Var, | NA | - | Review, | Sepsis, | NA |
| 2885- | HNK, | Honokiol: a novel natural agent for cancer prevention and therapy |
| 2897- | HNK, | Honokiol Inhibits Proliferation, Invasion and Induces Apoptosis Through Targeting Lyn Kinase in Human Lung Adenocarcinoma Cells |
| - | in-vitro, | Lung, | PC9 | - | in-vitro, | Lung, | A549 |
| 4238- | HNK, | Neuropharmacological potential of honokiol and its derivatives from Chinese herb Magnolia species: understandings from therapeutic viewpoint |
| - | Review, | AD, | NA | - | NA, | Park, | NA |
Query results interpretion may depend on "conditions" listed in the research papers. Such Conditions may include : -low or high Dose -format for product, such as nano of lipid formations -different cell line effects -synergies with other products -if effect was for normal or cancerous cells
Filter Conditions: Pro/AntiFlg:% IllCat:% CanType:% Cells:% prod#:% Target#:309 State#:% Dir#:%
wNotes=0 sortOrder:rid,rpid