angioG Cancer Research Results

angioG, angiogenesis: Click to Expand ⟱
Source:
Type:
Process through which new blood vessels.
Angiogenesis, the process of new blood vessel formation from pre-existing vessels, plays a crucial role in cancer progression and metastasis. Tumors require a blood supply to grow beyond a certain size and to spread to other parts of the body.
Vascular Endothelial Growth Factor (VEGF): VEGF is one of the most important pro-angiogenic factors. It stimulates endothelial cell proliferation and migration, leading to the formation of new blood vessels. Many tumors overexpress VEGF, which correlates with poor prognosis.
Hypoxia-Inducible Factor (HIF): In response to low oxygen levels (hypoxia), tumors can activate HIF, which in turn promotes the expression of VEGF and other angiogenic factors. This mechanism allows tumors to adapt to their microenvironment and sustain growth.
-Tumour development and progression beyond a size of few millimetres‐cubed crucially depends on the onset of angiogenesis, that is, the ‘angiogenic switch’
Scientific Papers found: Click to Expand⟱
7691- IP6,    Inositol Hexaphosphate Suppresses Growth and Induces Apoptosis in Prostate Carcinoma Cells in Culture and Nude Mouse Xenograft: PI3K-Akt Pathway as Potential Target
- vitro+vivo, Pca, PC3 - in-vitro, Pca, C4-2B
TumCP↓, Apoptosis↑, Casp3↑, cl‑PARP↑, Akt↓, PI3K↓, p‑GSK‐3β↓, cycD1/CCND1↓, TumVol↓, TumW↓, PCNA↓, angioG↓, CD31/PECAM-1↓, ILK↓, VEGF↓, eNOS↓, Hif1a↓,
7750- ISL,    Isoliquiritigenin in Breast Cancer: A Systematic Review of Its Preventive and Anti-metastatic Mechanisms
- Review, BC, NA
AntiCan↑, Apoptosis↑, TumAuto↑, mTOR↓, AApath↓, EMT↓, BRCA1↝, PI3K↓, Akt↓, angioG↓, VEGF↓, Hif1a↓, COX2/PTGS2↓, NF-kB↓,
7749- ISL,    Inhibition of COX-2, mPGES-1 and CYP4A by isoliquiritigenin blocks the angiogenic Akt signaling in glioma through ceRNA effect of miR-194-5p and lncRNA NEAT1
- in-vitro, GBM, U87MG
angioG↓, COX2/PTGS2↓, mPGES-1↓, CYP4A/CYP4A11/CYP4A22↓, FGF21↓, TGF-β↓, VEGF↓, miR-194↑, NEAT1↓,
7756- ISL,    Dietary compound isoliquiritigenin inhibits breast cancer neoangiogenesis via VEGF/VEGFR-2 signaling pathway
- vitro+vivo, BC, MCF7 - vitro+vivo, BC, MDA-MB-231
AntiCan↑, VEGF↓, TumCI↓, TumCMig↓, Hif1a↓, TumCG↓, angioG↓, VEGFR2/KDR/Flk1↓, Apoptosis↑, toxicity↓, TumCCA↑, Inflam↓, ROS↑,
7778- ISL,    Isoliquiritigenin, a potent human monoamine oxidase inhibitor, modulates dopamine D1, D3, and vasopressin V1A receptors
- Study, Park, NA - Study, AD, NA
*neuroP?, TumCP↓, *Inflam↓, *hepatoP↑, angioG↓, *AntiBio↑, *AntiDiabetic↓, *ROS↓, *antiOx↑, *MAOA↓, *MAOB↓,
7735- isoFl,    Soy Isoflavones in Integrative Oncology: Increased Efficacy and Decreased Toxicity of Cancer Therapy
- Review, Var, NA
Risk↓, ChemoSen↑, chemoP↑, RadioS↑, radioP↑, NF-kB↓, DNMTs↓, TumMeta↓, angioG↓, antiOx↑, BioAv↑, toxicity↓,
7730- isoFl,    Anticancer Potential of Isoflavones: A Narrative Overview of Mechanistic Insights and Experimental Evidence from the Past Ten Years
- Review, Var, NA
Apoptosis↑, ROS↓, TumCCA↓, TumCMig↓, TumCI↓, MMP↓, angioG↓, ChemoSen↑, p‑Akt↓, p‑mTOR↓, cl‑PARP↑, cycA1/CCNA1↓, CycB/CCNB1↓, STAT3↓,
7866- isoO,    Orientin and Cancer Suppression: Molecular Mechanisms and Synergistic Effects
- Review, Var, NA
TumCP↓, Apoptosis↑, angioG↓, TumMeta↓, selectivity↑, *toxicity↓, Bax:Bcl2↑, Cyt‑c↑, Diablo↑, Casp9↑, Casp3↑, cl‑PARP↑, DNAdam↑, γH2AX↑, ROS↑, PCNA↓, MMP2↓, MMP9↓, TumCCA↑, cycD1/CCND1↓, CDK4↓, P21↑, NF-kB↓, HH↓, Ki-67↓, COX2/PTGS2↓, TNF-α↓, ChemoSen↑, chemoP↑, eff↑, angioG↓,
7983- itraC,    Antifungal drug itraconazole targets VDAC1 to modulate the AMPK/mTOR signaling axis in endothelial cells
- in-vitro, Nor, HUVECs
angioG↓, VDAC1↓, mt-ATP↓, AMPK↑, mTOR↓, TumCP↓,
8000- itraC,    The anti-cancer effects of itraconazole in epithelial ovarian cancer
- in-vivo, Ovarian, NA
ChemoSen↑, HH↓, mTOR↓, angioG↓, VEGFR2/KDR/Flk1↓,
8001- itraC,    Repurposing itraconazole as an anticancer agent
- Review, Var, NA
*AntiFungal↑, AntiCan↑, P-gp/ABCB1↓, HH↓, mTOR↓, Wnt↓, β-catenin/ZEB1↓, angioG↓, LymphAG↓, ChemoSen↑, OS↑, Gli1↓, Ki-67↓, CSCs↓,
7982- itraC,    Simultaneous Targeting of NPC1 and VDAC1 by Itraconazole Leads to Synergistic Inhibition of mTOR Signaling and Angiogenesis
- in-vitro, Nor, HUVECs - in-vitro, Lung, A549 - in-vitro, Cerv, HeLa - in-vitro, Nor, HEK293
angioG↓, mTOR↓, NPC1L1↓, AMPK↑, VDAC1↓,
7984- itraC,    The antifungal drug itraconazole inhibits vascular endothelial growth factor receptor 2 (VEGFR2) glycosylation, trafficking, and signaling in endothelial cells
- in-vitro, Nor, NA
VEGFR2/KDR/Flk1↓, angioG↓, toxicity↓, mTOR↓,
7991- itraC,    A Phase II Trial of Perioperative Oral Itraconazole for the Management of Low-Risk Basal Cell Carcinoma
- Trial, BCC, NA
Smo↓, Dose↓, TumVol↓, Endoglin↓, angioG↓, toxicity↝, GLI3↓, toxicity↓,
7989- itraC,    Concentration-dependent Early Antivascular and Antitumor Effects of Itraconazole in Non-Small Cell Lung Cancer
- Trial, NSCLC, NA
Dose↝, TumVol↓, angioG↓, IL1β↓, GM-CSF↓, HH∅, BioAv↝, other↝,
7987- itraC,    Repurposing itraconazole as a treatment for advanced prostate cancer: a noncomparative randomized phase II trial in men with metastatic castration-resistant prostate cancer
- Trial, Pca, NA
angioG↓, HH↓, Dose↝, PSA↓, CTC↓, other↝, toxicity↝,
8016- itraC,    Impact of combination chemotherapy with itraconazole on survival for patients with recurrent or persistent ovarian clear cell carcinoma
- Human, Ovarian, NA
P-gp/ABCB1↓, angioG↓, HH↓, OS↑, Dose↝,
8014- itraC,    Itraconazole inhibits angiogenesis and tumor growth in non-small cell lung cancer
- vitro+vivo, NSCLC, NA
TumCP↓, TumCMig↓, ChemoSen↑, angioG↓, Hif1a↑,
2180- itraC,    Repurposing Drugs in Oncology (ReDO)—itraconazole as an anti-cancer agent
- Review, Var, NA
Dose↝, toxicity↝, BioAv↑, Half-Life↝, BioAv↑, Dose↝, HH↓, TumAuto↑, Akt↓, mTOR↓, angioG↓, MDR1↓, TumCP↓, ChemoSen↑,
2179- itraC,    Repurposing itraconazole for the treatment of cancer
- Review, Var, NA
HH↓, angioG↓, TumCCA↑, MDR1↓, P-gp/ABCB1↓, mTOR↓, VEGF↓, Smo↓, Gli1↓, OS↑, PSA↓,
8035- IVM,    Ivermectin and non-parasitic disorders: An update
- Review, Var, NA - Review, AD, NA - Review, Stroke, NA
*AntiP↑, angioG↓, *AntiCan↓, mtDam↑, Apoptosis↑, necrosis↑, TumAuto↑, ROS↑, *neuroP↑, *Stroke↝, *cardioP↑,
8031- IVM,    Antiparasitic agents in oncology: Innovative mechanisms, emerging evidence and clinical potential in cancer treatment
- Review, Nor, NA
*AntiP↑, Wnt↓, β-catenin/ZEB1↓, PI3K↓, Akt↓, mTOR↓, HH↓, Imm↑, CSCs↓, P-gp/ABCB1↓, Chl↓, angioG↓,
8027- IVM,    Progress in Understanding the Molecular Mechanisms Underlying the Antitumour Effects of Ivermectin
- Review, Var, NA
*AntiP↑, TumCD↑, PAK1↑, TumAuto↑, Casp↑, ICD↑, TCF↝, Hippo↓, Akt↓, mTOR↓, angioG↓, CSCs↓, MMP↓, Cyt‑c↑, Apoptosis↑, BAX↑, P53↑, Bcl-2↓, cycE/CCNE↓, cycD1/CCND1↓, CDK2↓, CDK6↓, CDK4↓, YAP/TEAD↓, TFE3↑, mTORC1↓, mitResp↓, OCR↓, compI↓, MMP↓, ROS↑, SOD2↑, ATP↓, eff↓, mitA↓, P-gp/ABCB1↓, TumVol↓,
7896- IVT,  VT,    Molecular targets of vitexin and isovitexin in cancer therapy: a critical review
- Review, Var, NA
chemoPv↑, Dose↝, ACE/ACE1↓, Ca+2↓, *iNOS↓, *COX2/PTGS2↓, *ROS↓, *Stroke↓, Apoptosis↑, MMP↓, Bcl-2↓, Casp3↑, Casp9↑, TumAuto↑, HSP90↑, ER Stress↑, Hif1a↓, TumMeta↓, angioG↓, Tf↓, MAPK↓, PI3K↓, Akt↓, β-catenin/ZEB1↓, TumCCA↑, FOXO3↓, mTOR↓,
7906- IVT,    Isovitexin accelerates diabetic wound repair via coordinated angiogenesis and collagen remodeling: Mechanistic insights from cellular and streptozotocin-induced SD rat models
- in-vivo, Nor, NA
*Inflam↓, *Wound Healing↑, *angioG↑, *ROS↓, *Apoptosis↓, *PI3K↑, *Akt↑, *eNOS↑,
7961- JG,    Juglone Inhibits Tumor Metastasis by Regulating Stemness Characteristics and the Epithelial-to-Mesenchymal Transition in Cancer Cells both in Vitro and in Vivo
- vitro+vivo, BC, MCF7 - in-vitro, BC, 4T1 - vitro+vivo, CRC, HCT116
EMT↓, CSCs↓, TumMeta↓, Pin1↓, TumCCA↑, angioG↓, Apoptosis↑, BAX↑, Bcl-2↓,
8007- JG,    Juglone reduces growth and migration of U251 glioblastoma cells and disrupts angiogenesis
- in-vitro, GBM, U251
Pin1↓, AntiCan↑, TumCP↓, Apoptosis↑, Casp3↑, TumCMig↓, angioG↓, VEGF↓, CD31/PECAM-1↓, TGF-β1↓,
5120- JG,    Juglone can inhibit angiogenesis and metastasis in pancreatic cancer cells by targeting Wnt/β-catenin signaling
- in-vitro, PC, NA
angioG↓, Wnt↓, VEGF↓,
8085- KAE,    Effects and Mechanisms of Kaempferol in the Management of Cancers through Modulation of Inflammation and Signal Transduction Pathways
- Review, Var, NA
Apoptosis↑, TumCCA↑, angioG↓, PI3K↓, Akt↓, STAT3↓, AP-1↓, NRF2↓, BioAv↑, Inflam↓, NF-kB↓, TNF-α↓, VEGF↓, BAX↑, Casp↑, Bcl-2↓, P53↑, PTEN↑, hTERT/TERT↓, NRF2↓, ROS↑, DR5↑, ERK↑, CHOP/DDIT3↑, DR4↑, JNK↑, Ki-67↓, ChemoSen↑,
8087- KAE,    Therapeutic Importance of Kaempferol in the Treatment of Cancer through the Modulation of Cell Signalling Pathways
- Review, Var, NA
TumCCA↓, ROS↝, Apoptosis↑, TumCP↑, TumMeta↓, angioG↓, PI3K↓, EMT↓, Snail↓, E-cadherin↓, N-cadherin↓, MMP2↓, Casp9↑, Casp7↑, PARP↑, Apoptosis↑, *ROS↓, Hif1a↓, p‑Akt↓, P53↑, cMyc↓, Glycolysis↓, PKM2↓, miR-339-5p↝, BioAv↓,
8095- KAE,    Kaempferol: A Key Emphasis to Its Anticancer Potential
- Review, Var, NA
*AntiBio↑, *Inflam↓, *AntiTum↓, *antiOx↑, *cardioP↑, *neuroP↑, *AntiDiabetic↑, Risk↓, TumCCA↑, EMT↓, PI3K↓, Akt↓, MMP2↓, Casp3↑, Casp7↑, Casp9↑, PARP↑, *ROS↓, angioG↓, *BioAv↑, BioAv↑, selectivity↑, GLUT1↓, MCT1↓, ROS↓, ROS↑, Trx↓, Cyt‑c↑, MMP↓, miR-21↓, SOCS-3↓, STAT3↓, CDK1↓, CycB/CCNB1↑, HIF-1↓, JAK1↑, PTEN↑,
8072- KAE,    Natural defense against colorectal cancer: the effects of kaempferol on epigenetics, apoptosis, inflammation, oxidative stress, and cell proliferation
- Review, CRC, NA
AntiCan↑, TumCP↓, TumCI↓, Inflam↓, angioG↓, ROS↑, Apoptosis↑, ChemoSen↑, Risk↓, *antiOx↑, *Inflam↓, *AntiBio↑, *cardioP↑, *neuroP↑, selectivity↑, PUMA↑, Cyt‑c↑, cl‑Casp3↑, cl‑PARP↑, Apoptosis↑, NF-kB↓, COX2/PTGS2↓, CC(CDKs/cyclins)↓, TumCCA↑, BioAv↓, Synergy↑, DR4↑, DR5↑, Casp3↑, Casp9↑, Casp7↑, TumCP↓, TumCI↓, TumAuto↑, mtDam↑, P53↑, MAPK↑, *lipid-P↓, *TAC↑, *Catalase↑, *SOD↑, *GPx↑, *NRF2↑,
8075- KAE,  QC,    Systematic review on anticancer potential of Kaempferol and quercetin against lung, breast, and colorectal cancers with emphasis on in vitro and in vivo studies
- Review, Var, NA
tumCV↓, Apoptosis↑, TumCP↓, TumCMig↓, PI3K↓, Akt↓, MAPK↓, NF-kB↓, P53↑, Bcl-2↓, PARP↑, ERK↓, IQGAP3↓, γH2AX↑, cl‑Casp3↑, cl‑Casp9↑, Rho↓, Rac1↓, MMP2↓, MMP9↓, CTSB↓, CTSD↓, O-Glc↓, SERPINH1/HSP47↓, EMT↓, angioG↓, EGF↓, VEGFR2/KDR/Flk1↓, RadioS↑,
8076- KAE,    Kaempferol suppresses prostate cancer metastasis and tumor angiogenesis via disrupting the LIMK1/Cofilin pathway
- in-vivo, Pca, NA
AntiTum↑, TumCP↓, TumCCA↑, VEGF↓, CDK4↓, CDK6↓, LIMK1↓, Cofilin↓, angioG↓,
8081- KAE,    The Anticancer Effects and Therapeutic Potential of Kaempferol in Triple-Negative Breast Cancer
- Review, BC, NA
*antiOx↓, *Inflam↓, *neuroP↓, *AntiCan↑, DNAdam↓, Casp3↑, Casp9↑, p‑AMT/GCST/T-protein↑, ROS↑, NRF2↑, Apoptosis↑, cl‑PARP↓, BAX↑, Bcl-2↓, TumCCA↓, angioG↓, MMP3↓, MMP9↓, ChemoSen↑, BioAv↓, Glycolysis↓, cl‑PARP↑, Ca+2↑, MMP↓, ER Stress↑, GRP78/BiP↑, CHOP/DDIT3↑, ATF6↑, angioG↓, VEGF↓, Hif1a↓, chemoP↑, *ROS↓, NRF2↑, BioAv↑,
8055- KAE,    Molecular Mechanisms of the Anticancer Activity of the Flavonoid Kaempferol: A Comprehensive Review
- Review, Var, NA
antiNeop↑, *toxicity↓, TumCCA↑, ROS↑, ER Stress↑, TumAuto↑, Pyro↑, Ferroptosis↑, angioG↓, Imm↝, Synergy↑, ChemoSen↑, MPT↑, MMP↓, mtDam↑, Cyt‑c↑, Bax:Bcl2↑, Fas↑, DR4↑, DR5↑, JNK↑, ERK↑, CHOP/DDIT3↑, ER Stress↑, UPR↑, Ca+2↑, PI3K↓, Akt↓, mTOR↓, AMPK↑, *Ferroptosis↓, *antiOx↑, *NRF2↑, *GPx4↑, *ROS↓, *MDA↓, *i-Iron↓, *xCT/SLC7A11↑, VEGF↓, Wnt↓, β-catenin/ZEB1↓, EMT↓, STAT3↓, M2 MC↓, MCP1/CCL2↓, MMP9↓, MMP2↓, TIMP2↓, ChemoSen↑, PKM2↑, Glycolysis↓, CSCs↓, SOX4↓, OCT4↓, CD44↓, Nanog↓, MDR1↓, *GutMicro↑,
8253- LCA,    Licochalcone A, a natural chalconoid isolated from Glycyrrhiza inflata root, induces apoptosis via Sp1 and Sp1 regulatory proteins in oral squamous cell carcinoma
- in-vitro, SCC, HSC4
*AntiTum↑, *angioG↓, *AntiP↑, *antiOx↑, *Bacteria↓, *Inflam↓, tumCV↓, Sp1/3/4↓, p27/CDKN1B↑, P21↑, cycD1/CCND1↓, Mcl-1↓, survivin↓, Apoptosis↑,
8235- LCA,    Anticancer effects of licochalcones: A review of the mechanisms
- Review, Var, NA
mt-Apoptosis↑, TumAuto↑, TumCMig↓, LC3‑Ⅱ/LC3‑Ⅰ↑, ATG5↑, ATG7↑, p62↑, CHOP/DDIT3↑, ER Stress↑, UPR↑, ATG3↑, Beclin-1/ATG6↑, ATG16L1↑, PERK↑, ATF4↑, ATP↓, Hif1a↓, GLUT1↓, PDK1 / PDPK1↓, Bcl-xL↓, Bcl-2↓, BAD↑, BAX↑, Casp3↑, survivin↓, EGFR↓, ERK↓, Akt↓, mtDam↑, MMP↓, Cyt‑c↑, Casp↑, MDM2↓, CycB/CCNB1↓, CDC2↓, CDC25↓, TumCCA↑, TumCP↓, Wnt↓, β-catenin/ZEB1↓, Sp1/3/4↓, MMP-10↓, MMP3↓, TumCI↓, Imm↑, PD-L1↓, ROS↑, 4E-BP1↓, eIF2α↓, PI3K↓, mTOR↓, p‑cMET↑, Ca+2↑, RUBCN↓, ATG13↑, TSC1↑, TSC2↑, PRAS40↑, PP2A↑, ULK1/ATG1↑, THEM4/CTMP↑, DR5↑, Fas↑, TNFRSF25/DR3/APO3/LARD/TRAMP/WSL1↑, PKCδ↓, P70S6K↓, VEGF↓, angioG↓, HK2↓, Glycolysis↓, TrxR1↓, APAF1↑, cl‑PARP↑, Bax:Bcl2↑, ABCG2↓, BioEnh↑,
8335- LDN,    The opioid growth factor (OGF) and low dose naltrexone (LDN) suppress human ovarian cancer progression in mice
- vitro+vivo, Ovarian, SKOV3
OGF↑, OGFr↑, Dose↝, TumW↓, TumNum?, TumCP↓, angioG↓, toxicity↓,
8293- lign,  FS,    Flaxseed and its lignans inhibit estradiol-induced growth, angiogenesis, and secretion of vascular endothelial growth factor in human breast cancer xenografts in vivo
- in-vivo, BC, MCF7
TumCG↓, angioG↓, VEGF↓, Dose↝,
8292- lign,    Anticancer potential of flaxseed lignans, their metabolites and synthetic counterparts in relation with molecular targets: current challenges and future perspectives
- Review, Var, NA
*BioAv↝, chemoPv↑, Apoptosis↑, TumCP↓, TumMeta↓, angioG↓, *AntiDiabetic↑, *antiOx↑, *AntiCan↑, *Inflam↓, *cardioP↑, TumCCA↑, PSA↓, miR-106b↓, IGF-1↓, ERK↓, Akt↓, Bcl-2↓, p‑FAK↓, radioP↑, P-gp/ABCB1↓, ChemoSen↑, MMP↓, ROS↑, BioAv↓, *toxicity↓, chemoP↑,
8327- LIN,    Recent updates on bioactive properties of linalool
- Review, Var, NA
*AntiCan↑, *AntiBio↑, *neuroP↑, *Stress↓, *hepatoP↑, *RenoP↑, *ROS↓, ROS↑, *Inflam↓, *toxicity↓, TumCP↓, TumCCA↑, mtDam↑, MMP↓, compI↓, compII↓, ETC↓, ATP↓, angioG↓, ChemoSen↑, *GSH↑, *MDA↓, *lipid-P↓, *NRF2↑, *HO-1↑, *ALAT↓, *AST↓, chemoP↑,
8326- LIN,    Linalool in cancer pharmacology: pharmacokinetic limitations and preclinical cytotoxic evidence for translational development
- Review, Var, NA
Dose↝, *BioAv↓, BioAv↝, tumCV↓, compI↓, compII↓, ROS↑, ATP↓, GSH↓, mtDam↑, Casp↑, NF-kB↓, MMP↓, TumCCA↑, PI3K↓, Akt↓, angioG↓, CD31/PECAM-1↓, Ki-67↓,
8378- LT,    Luteolin and its derivatives: modulation of epithelial-mesenchymal transition in fibrosis and cancer
- Review, Var, NA
EMT↓, TGF-β1↓, Smad1↓, PI3K↓, Akt↓, Hippo↝, YAP/TEAD↓, *NRF2↑, *HO-1↑, *ROS↓, E-cadherin↑, ZO-1↑, Vim↓, CLDN1↓, β-catenin/ZEB1↓, Snail↓, TCF↓, Zeb1↓, angioG↓, eff↑, ROS↑, mtDam↑, MMP↓, ETC↓,
8393- LT,    Progress, pharmacokinetics and future perspectives of luteolin modulating signaling pathways to exert anticancer effects: A review
- Review, Var, NA
TumCP↓, TumMeta↓, angioG↓, EMT↓, Imm↝, ChemoSen↑, *Inflam↓, *COX2/PTGS2↓, *NF-kB↓, MMP2↓, MMP9↓, p‑Akt↓, p‑PI3K↓, IGF-2↓, IGF-1R↓, CXCL16↓, NOTCH1↓, HES1↓, VEGF↓, ROS↑,
8401- LT,    Multi-Faceted Role of Luteolin in Cancer Metastasis: EMT, Angiogenesis, ECM Degradation and Apoptosis
- Review, Var, NA
EMT↓, N-cadherin↓, Vim↓, VEGF↓, VEGFR1↓, MMPs↓, Telomerase↓, NF-kB↓, cMyc↓, Bax:Bcl2↑, Casp3↑, PI3K↓, Akt↓, FOXO3↑, P21↑, p27/CDKN1B↑, cl‑PARP↑, Cyt‑c↑, NOTCH↓, HES1↓, ROS↑, SOD↓, miR-34b-5p↑, Hif1a↓, P21↓, survivin↓, Mcl-1?, Bcl-xL↓, MDM2↓, MMP2↓, MMP9↓, MMP3↓, MMP16↓, miR-384↑, NRF2↓, HO-1↓, angioG↓,
8397- LT,    Effects and Mechanisms of Luteolin, a Plant-Based Flavonoid, in the Prevention of Cancers via Modulation of Inflammation and Cell Signaling Molecules
- Review, Var, NA
tumCV↓, TumCP↓, angioG↓, TumCI↓, TumMeta↓, mTOR↓, PI3K↓, Akt↓, STAT3↓, Wnt↓, β-catenin/ZEB1↓, TumCCA↑, Apoptosis↑, hTERT/TERT↓, AP-1↓, NF-kB↓, MAPK↓, HSP90↓, AR↓, IGF-1R↓, Akt↓, NOTCH↓, IL6↓, MMP2↓, MMP3↓, MMP9↓, MMP16↓, TumVol∅, TumW∅, miR-34a↑, miR-107↑, miR-139-5p↑, miR-422a↑, miR-21↓, miR-155↓, miR-224↓, miR-340↓, *toxicity↓,
2906- LT,    Luteolin, a flavonoid with potentials for cancer prevention and therapy
- Review, Var, NA
*Inflam↓, AntiCan↑, antiOx⇅, Apoptosis↑, TumCP↓, TumMeta↓, angioG↓, PI3K↓, Akt↓, NF-kB↓, XIAP↓, P53↑, *ROS↓, *GSTA1↑, *GSR↑, *SOD↑, *Catalase↑, *other↓, ROS↑, Dose↝, chemoP↑, NF-kB↓, JNK↑, p27/CDKN1B↑, P21↑, DR5↑, Casp↑, Fas↑, BAX↑, MAPK↓, CDK2↓, IGF-1↓, PDGF↓, EGFR↓, PKCδ↓, TOP1↓, TOP2↓, Bcl-xL↓, FASN↓, VEGF↓, VEGFR2/KDR/Flk1↓, MMP9↓, Hif1a↓, FAK↓, MMP1↓, Twist↓, ERK↓, P450↓, CYP1A1↓, CYP1A2↓, TumCCA↑,
2909- LT,    Revisiting luteolin: An updated review on its anticancer potential
- Review, Var, NA
Apoptosis↑, TumCCA↑, angioG↓, TumMeta↓, TumCP↓, chemoP↑, MDR1↓,
2912- LT,    Luteolin: a flavonoid with a multifaceted anticancer potential
- Review, Var, NA
ROS↑, TumCCA↑, TumCP↓, angioG↓, ER Stress↑, mtDam↑, PERK↑, ATF4↑, eIF2α↑, cl‑Casp12↑, EMT↓, E-cadherin↑, N-cadherin↓, Vim↓, *neuroP↑, NF-kB↓, PI3K↓, Akt↑, XIAP↓, MMP↓, Ca+2↑, BAX↑, Casp3↑, Casp9↑, Bcl-2↓, Cyt‑c↑, IronCh↑, SOD↓, *ROS↓, *LDHA↑, *SOD↑, *GSH↑, *BioAv↓, Telomerase↓, cMyc↓, hTERT/TERT↓, DR5↑, Fas↑, FADD↑, BAD↑, BOK↑, BID↑, NAIP↓, Mcl-1↓, CDK2↓, CDK4↓, MAPK↓, AKT1↓, Akt2↓, *Beclin-1/ATG6↓, Hif1a↓, LC3II↑, Beclin-1/ATG6↑,

Showing Research Papers: 251 to 300 of 463
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* indicates research on normal cells as opposed to diseased cells
Total Research Paper Matches: 463

Pathway results for Effect on Cancer / Diseased Cells:


NA, unassigned(tgid=0) ⓘ

NA↑, 2,   NA↝, 1,  

Redox & Oxidative Stress(tgid=1) ⓘ

antiOx↓, 2,   antiOx↑, 14,   antiOx⇅, 1,   ARE↓, 1,   Catalase↓, 2,   Catalase↑, 3,   Copper↓, 2,   Fenton↑, 4,   frataxin↑, 1,   GPx↑, 4,   GPx4↓, 4,   GSH↓, 28,   GSH↑, 3,   GSH⇅, 1,   GSH/GSSG↓, 1,   GSR↓, 1,   ox-GSSG↑, 1,   GSTs↓, 1,   H2O2↓, 1,   H2O2↑, 4,   HO-1↓, 6,   HO-1↑, 10,   HO-2↓, 1,   Iron↑, 2,   Iron∅, 1,   Keap1↓, 2,   lipid-P?, 1,   lipid-P↓, 3,   lipid-P↑, 15,   MDA↓, 3,   MDA↑, 2,   NOX↓, 1,   NQO1↑, 1,   NRF2↓, 17,   NRF2↑, 17,   Prx↓, 2,   Prx4↑, 1,   PrxI↓, 1,   PrxII↓, 1,   PYCR1↓, 1,   RNS↑, 1,   ROS?, 1,   ROS↓, 18,   ROS↑, 176,   ROS⇅, 3,   ROS↝, 5,   i-ROS↑, 1,   mt-ROS↑, 5,   SOD↓, 5,   SOD↑, 7,   SOD1↓, 2,   SOD1↑, 1,   SOD2↑, 2,   TBARS↑, 1,   Thiols↓, 3,   Trx↓, 2,   ox-Trx1↑, 1,   TrxR↓, 6,   TrxR1↓, 2,   xCT/SLC7A11↓, 1,  

Metal & Cofactor Biology(tgid=2) ⓘ

ATOX1↝, 1,   Ferritin↓, 2,   IronCh↑, 2,   NCOA4↑, 1,   Tf↓, 2,   Tf↑, 1,  

Mitochondria & Bioenergetics(tgid=3) ⓘ

ADP:ATP↑, 1,   BCR-ABL↓, 1,   CDC2↓, 3,   CDC25↓, 6,   compI↓, 3,   compII↓, 2,   EGF↓, 5,   ETC↓, 5,   HSP60/HSPD1↓, 2,   mitResp↓, 2,   Mortalin↓, 1,   mtDam↓, 1,   mtDam↑, 17,   OCR↓, 5,   OCR↑, 2,   OXPHOS↓, 2,   OXPHOS↑, 3,   PDH↓, 1,   PINK1↑, 1,   SDH↓, 1,   SIRT3↓, 1,   VDAC1↓, 2,  

Core Metabolism/Glycolysis(tgid=4) ⓘ

12LOX↓, 1,   5LO↓, 3,   AApath↓, 1,   ACC↓, 1,   ACC↑, 1,   ALAT↓, 3,   AMP↓, 1,   AMPK↓, 1,   AMPK↑, 17,   p‑AMPK↑, 1,   p‑AMT/GCST/T-protein↑, 1,   ARG↓, 1,   ATP↓, 15,   mt-ATP↓, 2,   CAIX/CA9↓, 1,   CBS↑, 1,   citrate↓, 1,   CPT1A↓, 1,   CYP4A/CYP4A11/CYP4A22↓, 1,   ECAR↓, 2,   ECAR↝, 1,   ENO1↓, 1,   FABP5/E-FABP↓, 1,   FASN↓, 5,   FASN↑, 1,   GAPDH↓, 1,   GlucoseCon↓, 3,   Glycolysis↓, 31,   GSK‐3β↓, 11,   GSK‐3β↑, 3,   p‑GSK‐3β↓, 4,   Histones↑, 1,   HK2↓, 11,   HMG-CoA↓, 2,   lactateProd↓, 5,   LDHA↓, 4,   LDL↓, 3,   LDL↑, 1,   lipoGen↓, 1,   NADPH↓, 4,   NADPH↑, 2,   NPC1L1↓, 2,   O-Glc↓, 1,   PCK1↓, 1,   PDK1 / PDPK1?, 2,   PDK1 / PDPK1↓, 8,   p‑PDK1 / PDPK1↓, 1,   PDK3↑, 1,   PDKs↓, 1,   PFK↓, 2,   PFK1↓, 1,   PFK2?, 1,   PKM2↓, 9,   PKM2↑, 1,   PKM2:PKM1↓, 1,   SIRT1↓, 8,   SIRT1↑, 9,   SIRT2↓, 1,   SREBP1/SREBF1↓, 1,   SREBP2↓, 1,   TCA↓, 2,   Warburg↓, 6,   β-oxidation↓, 1,  

Cell Death(tgid=5) ⓘ

AIF↑, 6,   APAF1↑, 5,   Apoptosis?, 1,   Apoptosis↓, 6,   Apoptosis↑, 180,   mt-Apoptosis↑, 3,   ASK1↑, 1,   BAD↓, 2,   BAD↑, 4,   Bak↑, 12,   BAX↓, 3,   BAX↑, 72,   BAX⇅, 1,   Bax:Bcl2↑, 22,   Bcl-2↓, 78,   Bcl-2↑, 2,   Bcl-xL↓, 27,   BID↓, 1,   BID↑, 3,   BIM↓, 1,   BIM↑, 5,   BNIP3↝, 1,   BOK↑, 1,   Casp↓, 2,   Casp↑, 34,   Casp↝, 1,   cl‑Casp↑, 1,   Casp10↑, 1,   Casp12?, 1,   Casp12↑, 1,   cl‑Casp12↑, 1,   Casp2↑, 1,   Casp3?, 1,   Casp3↓, 4,   Casp3↑, 95,   cl‑Casp3↑, 12,   proCasp3↑, 2,   Casp6↓, 1,   Casp6↑, 1,   Casp7↑, 15,   Casp8↓, 1,   Casp8↑, 23,   Casp8∅, 1,   cl‑Casp8↑, 3,   proCasp8↑, 1,   pro‑Casp8↑, 1,   Casp9↓, 1,   Casp9↑, 62,   cl‑Casp9↑, 7,   cFLIP↓, 2,   Cupro↑, 2,   Cyt‑c↑, 66,   Cyt‑c↝, 2,   Diablo↑, 8,   DR5↑, 22,   FADD↑, 7,   Fas↓, 2,   Fas↑, 18,   FasL↑, 7,   Ferroptosis↑, 12,   GSDME↑, 1,   IAP1↓, 8,   IAP2/BIRC3↓, 5,   ICAD↓, 1,   ICD↑, 1,   iNOS↓, 11,   Mcl-1?, 1,   Mcl-1↓, 29,   MDM2↓, 10,   MDM2↑, 1,   p‑MDM2↓, 1,   MOMP↓, 1,   MOMP↑, 5,   NAIP↓, 1,   Necroptosis↑, 4,   necrosis↑, 3,   NOXA↑, 4,   p38↓, 1,   p38↑, 13,   p‑p38↓, 3,   p‑p38↑, 2,   Paraptosis↑, 2,   PUMA↑, 6,   Pyro↑, 3,   RIP1↑, 1,   RIP3↑, 1,   survivin↓, 54,   TNFR 1↑, 1,   TRAIL↑, 2,   TRAIL⇅, 1,   TRAILR↑, 2,   TumCD↑, 16,   XIAP↓, 28,   YAP/TEAD↓, 6,  

Kinase & Signal Transduction(tgid=6) ⓘ

Akt↓, 123,   Akt↑, 8,   Akt↝, 1,   Akt∅, 1,   p‑Akt↓, 27,   AKT1↓, 2,   Akt2↓, 1,   BRAF↓, 1,   CK2↓, 3,   cMET↓, 3,   p‑cMET↑, 1,   CREB↓, 1,   CREB2↓, 1,   cSrc↓, 1,   DDIT4↑, 1,   DYRK1B↓, 1,   EGFR↓, 28,   EGFR↝, 1,   p‑EGFR↓, 1,   ERK↓, 36,   ERK↑, 8,   ERK↝, 2,   ERK∅, 1,   p‑ERK↓, 9,   p‑ERK↑, 1,   FGFR1↓, 2,   FOXD3↑, 2,   HER2/EBBR2↓, 10,   p‑HER2/EBBR2↓, 1,   Hippo↓, 1,   Hippo↝, 1,   IGF-1R↓, 3,   IGFR↓, 1,   IKKα↓, 6,   p‑IKKα↓, 1,   ILK↓, 1,   IκB↓, 1,   IκB↑, 1,   p‑IκB↓, 1,   JAK↓, 5,   JAK1↓, 3,   JAK1↑, 1,   JAK2↓, 10,   JNK↓, 3,   JNK↑, 13,   JNK↝, 1,   p‑JNK↓, 2,   LIMK1↓, 1,   MAPK↓, 33,   MAPK↑, 11,   MAPK↝, 1,   MEK↓, 5,   mTOR↓, 74,   mTOR↑, 1,   p‑mTOR↓, 3,   mTORC2↓, 2,   mTORC2↑, 1,   p70S6↓, 1,   p‑p70S6↓, 1,   P70S6K↓, 5,   p‑P70S6K↓, 1,   P90RSK↓, 1,   PDGFR-BB↓, 1,   p‑PDGFR-BB↓, 1,   PDGFRB↓, 1,   PI3K↓, 89,   PI3K↑, 1,   PI3K↝, 1,   p‑PI3K↓, 2,   PI3K/Akt↓, 1,   p‑PI3k/Akt/mTOR↓, 1,   PKCδ↓, 10,   PP2A↑, 1,   PRAS40↑, 1,   PTEN↓, 2,   PTEN↑, 24,   p‑PTEN↓, 1,   Raf↓, 3,   RAS↓, 10,   SHP1↑, 1,   Sp1/3/4↓, 16,   STAT↓, 3,   STAT3↓, 59,   STAT3↑, 2,   STAT3↝, 1,   p‑STAT3↓, 9,   p‑STAT3↑, 2,   STAT5↓, 1,   STAT6↓, 3,   THEM4/CTMP↑, 1,   TSC2↑, 1,  

Transcription & Epigenetics(tgid=7) ⓘ

ATF2↓, 1,   ATF3↑, 1,   ATF4↓, 1,   ATF4↑, 3,   ATF4↝, 1,   CBP↓, 2,   cJun↓, 3,   cJun↑, 2,   cMyc↓, 34,   cMyc↑, 1,   p‑cMyc↑, 1,   DNMT1↓, 6,   DNMT3A↓, 2,   DNMT3B↓, 2,   DNMTs↓, 6,   EZH2↓, 1,   FOXM1↓, 4,   FOXO↑, 1,   FOXO1↓, 2,   FOXO1↑, 1,   FOXO3↓, 5,   FOXO3↑, 6,   FOXO3↝, 1,   p‑FOXO3↓, 2,   H3↓, 2,   p‑H3↓, 1,   ac‑H3↑, 1,   H4↑, 1,   ac‑H4↑, 1,   HATs↓, 6,   HATs↑, 2,   HDAC↓, 23,   HDAC1↓, 7,   HDAC2↓, 1,   HDAC3↓, 1,   HDAC4↓, 2,   HDAC8↓, 2,   HES1↓, 2,   miR-106b↓, 1,   miR-107↑, 1,   miR-139-5p↑, 1,   miR-155↓, 1,   miR-194↑, 1,   miR-200b↑, 1,   miR-203↑, 1,   miR-205↑, 1,   miR-21↓, 5,   miR-21↑, 1,   miR-218↑, 1,   miR-224↓, 1,   miR-25-5p↓, 1,   miR-29b↑, 1,   miR-30a-5p↑, 1,   miR-339-5p↝, 1,   miR-340↓, 1,   miR-34a↑, 2,   miR-34b-5p↑, 1,   miR-375↑, 1,   miR-384↑, 1,   miR-422a↑, 1,   Myc↓, 5,   MYCN↓, 1,   NDRG1↑, 1,   NEAT1↓, 1,   OCT4↓, 8,   other?, 1,   other↓, 4,   other↑, 4,   other↝, 14,   SOX2↓, 3,   SOX4↓, 1,   SOX4↑, 1,   SOX9↓, 1,   SUV39H↓, 2,   TFE3↑, 1,   tumCV↓, 29,   tumCV↑, 1,  

Protein Folding & ER Stress(tgid=8) ⓘ

ATF6↑, 1,   CHOP/DDIT3↑, 17,   COX17↝, 1,   CUL1↝, 1,   CUL5↝, 1,   eIF2α↓, 1,   eIF2α↑, 2,   p‑eIF2α↑, 3,   ER Stress↓, 2,   ER Stress↑, 35,   GRP78/BiP?, 1,   GRP78/BiP↓, 2,   GRP78/BiP↑, 9,   HSP27↓, 2,   HSP27↑, 1,   HSP27↝, 1,   HSP70/HSPA5↓, 6,   HSP70/HSPA5↑, 1,   HSP70/HSPA5↝, 1,   HSP90↓, 16,   HSP90↑, 1,   HTRA↓, 2,   PERK↑, 6,   Proteasome↓, 1,   SERPINH1/HSP47↓, 1,   UPR↑, 4,   XBP-1↓, 1,   XBP-1↑, 1,  

Autophagy & Lysosomes(tgid=9) ⓘ

ATG13↑, 1,   ATG16L1↑, 1,   ATG3↑, 2,   ATG5↑, 4,   ATG7↑, 1,   Beclin-1/ATG6↓, 1,   Beclin-1/ATG6↑, 9,   CTSB↓, 1,   CTSD↓, 1,   LC3‑Ⅱ/LC3‑Ⅰ↑, 2,   LC3B↓, 1,   LC3B-II↑, 3,   LC3II↑, 10,   LC3s↑, 1,   p62↓, 4,   p62↑, 3,   p‑p62↑, 1,   PARK2↑, 1,   RUBCN↓, 1,   SESN2↑, 2,   TumAuto↓, 1,   TumAuto↑, 44,   TumAuto⇅, 1,   TumAuto↝, 1,   ULK1/ATG1↑, 1,  

DNA Damage & Repair(tgid=10) ⓘ

ATM↑, 3,   BRCA1↓, 3,   BRCA1↑, 2,   BRCA1↝, 1,   BRCA2↓, 1,   DFF45↓, 1,   DFF45↑, 2,   DNAdam↓, 3,   DNAdam↑, 48,   DNArepair↓, 5,   DNArepair↑, 1,   m-FAM72A↓, 1,   G9a↓, 1,   hTERT/TERT↓, 11,   MGMT↓, 1,   p16↑, 2,   P53?, 1,   P53↑, 64,   P53↝, 3,   p‑P53↑, 2,   PARP↓, 1,   PARP↑, 15,   cl‑PARP↓, 2,   cl‑PARP↑, 52,   PARP1↑, 1,   PCNA↓, 20,   SIRT6↓, 1,   SIRT6↑, 1,   Telomerase↓, 15,   TOP1↓, 8,   TOP2↓, 6,   TOP2↑, 1,   TP53↑, 3,   TRF2↓, 1,   UHRF1↓, 1,   γH2AX↑, 3,  

Cell Cycle & Senescence(tgid=11) ⓘ

CC(CDKs/cyclins)↓, 1,   CDK1↓, 9,   CDK1↑, 2,   p‑CDK1↓, 2,   CDK2↓, 31,   CDK2↑, 2,   CDK4↓, 34,   CDK4↑, 2,   CDK4/6↓, 1,   CDK6↓, 17,   CDK6↑, 2,   CDK7↓, 1,   CDK8↓, 1,   CHK1↓, 1,   CHK1↑, 2,   Chk2↓, 1,   Chk2↑, 2,   Cyc↓, 3,   cycA1/CCNA1↓, 7,   CycB/CCNB1↓, 17,   CycB/CCNB1↑, 1,   cycD1/CCND1↓, 55,   CycD3↓, 3,   cycE/CCNE↓, 19,   cycE1↓, 1,   E2Fs↓, 5,   E2Fs↑, 1,   GADD45A↓, 1,   Ki-67↓, 21,   mitA↓, 1,   mitA↑, 1,   p19↑, 1,   P21?, 1,   P21↓, 2,   P21↑, 42,   p27/CDKN1B↑, 19,   pRB↑, 1,   p‑pRB↓, 1,   RB1↓, 1,   RB1↑, 2,   p‑RB1↓, 5,   Securin↓, 1,   TubPol↓, 1,   TumCCA?, 1,   TumCCA↓, 7,   TumCCA↑, 156,  

Proliferation, Differentiation & Cell State(tgid=12) ⓘ

4E-BP1↓, 3,   p‑4E-BP1↓, 1,   ALDH↓, 8,   Axin2↑, 1,   BMPs↑, 2,   CD133↓, 4,   CD133↑, 1,   CD24↓, 1,   CD34↓, 1,   cFos↓, 6,   cMYB↓, 2,   CSCs?, 1,   CSCs↓, 45,   CSCs↑, 2,   Diff↑, 4,   FGF↓, 2,   FGF↑, 1,   Gli↓, 1,   Gli1↓, 5,   HH↓, 10,   HH∅, 1,   HMGCR↓, 1,   IGF-1↓, 10,   IGF-2↓, 1,   IGFBP3↑, 4,   Jun↓, 1,   Ki-67↓, 21,   Let-7↑, 2,   mTORC1↓, 5,   Nanog↓, 6,   Nestin↓, 1,   NICD↓, 1,   NOTCH↓, 11,   NOTCH1↓, 8,   NOTCH1↑, 3,   OGF↑, 1,   OGFr↑, 1,   p300↓, 2,   PTCH1↓, 1,   PTCH2↓, 1,   SCF↓, 1,   Shh↓, 4,   Smo↓, 3,   STAT1↓, 1,   TAZ↓, 1,   TumCG↓, 87,   TumCG↑, 1,   TumCP↓, 145,   TumCP↑, 6,   tyrosinase↓, 1,   Wnt↓, 35,   Wnt/(β-catenin)↓, 2,  

Migration(tgid=13) ⓘ

AEG1↓, 1,   annexin II↓, 1,   AntiAg?, 1,   AP-1↓, 8,   ARG1/2↑, 1,   ASAP2↓, 1,   AXL↓, 1,   CA↓, 3,   Ca+2↓, 3,   Ca+2↑, 24,   Ca+2↝, 5,   i-Ca+2↑, 1,   CAFs/TAFs↓, 1,   cal2↓, 1,   CCN2/CTGF↓, 1,   Cdc42↓, 1,   Cdc42↑, 1,   Chl↓, 1,   Cofilin↓, 1,   COL1↓, 1,   COL3A1↓, 1,   COL4A3↓, 1,   E-cadherin↓, 5,   E-cadherin↑, 29,   EM↑, 1,   EMT↓, 64,   EMT↑, 2,   EpCAM↓, 3,   F-actin↓, 1,   FAK↓, 18,   p‑FAK↓, 4,   p‑FAK↑, 1,   Fibronectin↓, 2,   GLI2↓, 1,   GLI3↓, 1,   IQGAP3↓, 1,   ITGB1↓, 2,   ITGB3↓, 3,   ITGB6↓, 1,   KRAS↓, 1,   LEF1↓, 1,   MALAT1↓, 2,   MET↓, 1,   MMP-10↓, 2,   MMP1↓, 9,   MMP13↓, 3,   MMP14↓, 1,   MMP16↓, 2,   MMP2?, 1,   MMP2↓, 73,   MMP3↓, 9,   MMP7↓, 9,   MMP9?, 1,   MMP9↓, 91,   MMP9↑, 2,   MMPs↓, 39,   MUC4↓, 2,   N-cadherin↓, 17,   NEDD9↓, 1,   p‑p44↓, 1,   PAK1↓, 1,   PAK1↑, 1,   pax↓, 1,   PDGF↓, 10,   Rac1↓, 3,   RECK↑, 3,   Rho↓, 5,   Rho↑, 1,   ROCK1↓, 4,   ROCK1↑, 1,   Slug↓, 9,   Smad1↓, 2,   Smad1↝, 1,   p‑SMAD2↓, 1,   SMAD3↓, 2,   p‑SMAD3↓, 1,   Snail?, 1,   Snail↓, 16,   STAC2↓, 1,   TET1↑, 2,   TGF-β↓, 17,   TGF-β↑, 1,   TGF-β↝, 1,   TGF-β1↓, 2,   TIMP1↑, 10,   TIMP2↓, 1,   TIMP2↑, 13,   TIMP3↑, 1,   TRIB3↑, 1,   TSC1↑, 1,   TSP-1↑, 9,   TumCA↓, 1,   TumCI↓, 97,   TumCI↑, 1,   TumCMig↓, 76,   TumCMig↑, 3,   TumMeta?, 1,   TumMeta↓, 119,   TumMeta↑, 7,   Twist↓, 16,   TXNIP↑, 1,   uPA↓, 18,   uPAR↓, 2,   Vim↓, 24,   Zeb1↓, 7,   ZEB2↓, 2,   α-SMA↓, 2,   α-tubulin↓, 1,   β-catenin/ZEB1↓, 39,  

Angiogenesis & Vasculature(tgid=14) ⓘ

angioG↓, 420,   angioG↑, 10,   angioG∅, 1,   angioS↑, 1,   CD31/PECAM-1↓, 11,   EGR1↑, 1,   Endoglin↓, 1,   Endoglin↑, 1,   eNOS↓, 3,   HIF-1↓, 10,   Hif1a↓, 83,   Hif1a↑, 1,   Hif1a↝, 1,   LymphAG↓, 1,   NO↓, 3,   NO↑, 1,   TYMP/ECGF1↓, 1,   VCAM-1↓, 2,   VEGF↓, 173,   VEGF↑, 2,   VEGFR1↓, 4,   VEGFR2/KDR/Flk1↓, 31,  

Barriers & Transport(tgid=15) ⓘ

AQPs↓, 1,   BBB↑, 8,   CLDN1↓, 2,   CLDN1↑, 1,   CLDN2↓, 1,   CTR1↝, 1,   CX43/GJA1↓, 1,   EPR↑, 10,   GLUT1↓, 12,   GLUT2↓, 1,   GLUT4↓, 1,   IBI↑, 1,   MMP↓, 78,   MMP↑, 2,   MMP↝, 1,   MPT↑, 5,   NHE1↓, 2,   OCLN↑, 1,   TJ↑, 1,   TRPV1↑, 2,   ZO-1↑, 2,  

Immune & Inflammatory Signaling(tgid=16) ⓘ

CB2 / CNR2↑, 1,   CD4+↓, 1,   CD44↓, 13,   CD8+↑, 1,   COX1↓, 2,   COX2/PTGS2↓, 65,   COX2/PTGS2↑, 2,   CXCL16↓, 1,   CXCL6/GCP-2↓, 1,   CXCR2↓, 2,   CXCR4↓, 14,   DCells↑, 1,   DR4↑, 9,   Gal-3↓, 2,   GM-CSF↓, 3,   HLA-I/II↑, 1,   ICAM-1↓, 7,   IFN-γ↓, 2,   IFN-γ↑, 3,   Igs↑, 1,   IL1↓, 6,   IL10↓, 4,   IL10↑, 2,   IL12↓, 1,   IL12↑, 1,   IL1α↓, 1,   IL1β↓, 15,   IL2↓, 2,   IL2↑, 5,   IL4↓, 2,   IL4↑, 1,   IL6↓, 32,   IL8↓, 9,   Imm↑, 21,   Imm↝, 6,   INF-γ↑, 1,   Inflam↓, 44,   Inflam↝, 1,   LIF↑, 1,   LRIG1↑, 1,   M2 MC↓, 2,   pol-M2 MC↓, 1,   MCP1/CCL2↓, 6,   MCT1↓, 1,   MDSCs↓, 2,   MIP2↓, 1,   mPGES-1↓, 2,   MyD88↓, 1,   MyD88↑, 1,   NAF1↓, 1,   NF-kB↓, 137,   NF-kB↑, 3,   NF-kB↝, 2,   p‑NF-kB↓, 2,   p‑NF-kB↑, 2,   NK cell↑, 7,   NLRP3↓, 4,   NLRP3↑, 1,   p50↓, 1,   p65↓, 1,   PD-L1↓, 7,   PGE2↓, 16,   PSA↓, 6,   PSA∅, 1,   RAGE↓, 2,   SOCS-3↓, 1,   T-Cell↑, 1,   T-Cell↝, 1,   TCF↓, 3,   TCF↝, 1,   Th1 response↑, 1,   Th2↑, 1,   TLR4↓, 6,   TLR4↑, 1,   TLR4↝, 1,   TNF-α↓, 34,   TNF-α↑, 3,   TNFRSF25/DR3/APO3/LARD/TRAMP/WSL1↑, 1,   TRAF1↓, 1,   Treg lymp↓, 1,  

Cellular Microenvironment(tgid=17) ⓘ

IM↓, 1,   pH↝, 1,   e-pH↑, 1,   i-pH↓, 1,  

Synaptic & Neurotransmission(tgid=18) ⓘ

5HT↓, 1,   SYN1↑, 1,  

Protein Aggregation(tgid=19) ⓘ

Aβ↓, 1,   XO↓, 1,  

Hormonal & Nuclear Receptors(tgid=20) ⓘ

ACE/ACE1↓, 1,   AR↓, 12,   CYP17A1↓, 1,   CYP19↓, 2,   ER(estro)↓, 1,   ERα/ESR1↓, 1,   Estro↝, 1,   FGF21↓, 2,   GR↑, 1,   PPARα↓, 2,   cl‑PPARα↓, 1,   PPARγ↓, 2,   PPARγ↑, 3,  

Drug Metabolism & Resistance(tgid=21) ⓘ

ABCG2↓, 3,   BioAv↓, 50,   BioAv↑, 58,   BioAv↝, 8,   BioEnh↑, 5,   CBR1↓, 1,   chemoR↓, 1,   ChemoSen?, 1,   ChemoSen↓, 1,   ChemoSen↑, 159,   ChemoSen⇅, 1,   ChemoSen∅, 1,   CompStab?, 1,   CompStab↓, 3,   CompStab↑, 1,   CompStab↝, 1,   CYP1A1↓, 2,   CYP1A1↑, 3,   CYP1A2↓, 1,   CYP1A2↑, 1,   CYP2A3/CYP2A6↓, 1,   CYP2E1↑, 1,   CYP3A4↓, 3,   DDS↑, 5,   Dose?, 4,   Dose↓, 4,   Dose↑, 3,   Dose⇅, 1,   Dose↝, 53,   Dose∅, 8,   DrugR↓, 2,   eff?, 1,   eff↓, 30,   eff↑, 98,   eff↝, 10,   eff∅, 3,   GSTZ1↓, 1,   Half-Life↓, 16,   Half-Life↑, 5,   Half-Life↝, 9,   Half-Life∅, 2,   MDR1↓, 11,   MRP1/ABCC1↓, 3,   NAT↓, 1,   P-gp/ABCB1↓, 20,   P-gp/ABCB1↝, 1,   P450↓, 4,   RadioS?, 2,   RadioS↑, 49,   selectivity?, 1,   selectivity↑, 65,   Synergy↑, 100,  

Clinical Biomarkers(tgid=22) ⓘ

AFP↓, 1,   AFP↑, 1,   ALAT↓, 3,   ALP↓, 3,   AR↓, 12,   ascitic↓, 2,   AST↓, 2,   BRAF↓, 1,   BRCA1↓, 3,   BRCA1↑, 2,   BRCA1↝, 1,   CEC↝, 1,   CIT↓, 1,   CRP↓, 2,   CTC↓, 1,   E6↓, 1,   E7↓, 1,   EGFR↓, 28,   EGFR↝, 1,   p‑EGFR↓, 1,   ERα/ESR1↓, 1,   EZH2↓, 1,   Ferritin↓, 2,   FOXM1↓, 4,   HemoG↓, 1,   HER2/EBBR2↓, 10,   p‑HER2/EBBR2↓, 1,   hTERT/TERT↓, 11,   IL6↓, 32,   KRAS↓, 1,   LDH↓, 6,   LDH↑, 2,   Maspin↑, 1,   Myc↓, 5,   NOS2↓, 1,   PD-L1↓, 7,   PSA↓, 6,   PSA∅, 1,   RAGE↓, 2,   TP53↑, 3,   TRIB3↑, 1,  

Functional Outcomes(tgid=23) ⓘ

AntiAge↑, 1,   AntiCan↓, 1,   AntiCan↑, 60,   AntiCan∅, 1,   antiNeop↑, 3,   AntiTum↑, 23,   cardioP↑, 10,   CardioT↓, 1,   CardioT↑, 2,   chemoP↑, 29,   chemoPv↑, 25,   ChemoSideEff↓, 5,   fatigue↓, 3,   fatigue∅, 1,   hepatoP↓, 1,   hepatoP↑, 9,   Mucositis↓, 1,   neuroP↑, 8,   OS↑, 19,   OS∅, 1,   Pain↓, 1,   PFS↑, 1,   Pin1↓, 2,   QoL↑, 8,   QoL∅, 1,   radioP↑, 10,   Remission↑, 3,   RenoP↑, 7,   Risk↓, 19,   Risk↑, 2,   Sleep↑, 1,   toxicity↓, 27,   toxicity↑, 4,   toxicity↝, 11,   toxicity∅, 1,   TumNum?, 1,   TumVol↓, 26,   TumVol∅, 1,   TumW↓, 15,   TumW∅, 1,   Weight∅, 1,  

Infection & Microbiome(tgid=24) ⓘ

AntiBio↓, 1,   AntiViral↑, 1,   GutMicro↑, 6,   GutMicro↝, 1,   Sepsis↓, 1,  

Ingredients & Constituents(tgid=25) ⓘ

Ingr?, 1,   Ingr↝, 2,  
Total Targets: 996

Pathway results for Effect on Normal Cells:


Redox & Oxidative Stress(tgid=1) ⓘ

antiOx?, 1,   antiOx↓, 6,   antiOx↑, 75,   Catalase↑, 25,   DPPH↓, 1,   GPx↑, 20,   GPx1↑, 3,   GPx4↑, 2,   GSH↑, 20,   GSR↑, 3,   GSSG↓, 1,   GSTs↑, 9,   H2O2↓, 2,   HDL↑, 1,   HNE↓, 1,   HO-1↑, 11,   i-Iron↓, 1,   Keap1↓, 1,   Keap1↑, 1,   lipid-P↓, 23,   MDA↓, 13,   MPO↓, 1,   NADH↓, 1,   NOX4↓, 1,   Nrf1↑, 2,   NRF2↑, 24,   RNS↓, 1,   ROS↓, 79,   ROS↑, 2,   ROS∅, 1,   SAM-e↑, 1,   selenoP↑, 1,   SOD↑, 27,   SOD1↑, 3,   SOD2↑, 1,   TAC↑, 3,   TBARS↓, 1,   TOS↓, 1,   xCT/SLC7A11↑, 1,  

Metal & Cofactor Biology(tgid=2) ⓘ

IronCh↑, 3,  

Mitochondria & Bioenergetics(tgid=3) ⓘ

Insulin↓, 1,   OXPHOS↓, 1,   PGC-1α↑, 1,   SIRT3↑, 1,  

Core Metabolism/Glycolysis(tgid=4) ⓘ

15-LOX/ALOX15↓, 1,   5LO↓, 4,   5LO↝, 1,   ALAT?, 1,   ALAT↓, 5,   AMPK↓, 1,   AMPK↑, 3,   ATP↑, 1,   ATP↝, 1,   BHB↑, 1,   cytoP450↓, 1,   glucose↓, 5,   GlucoseCon↑, 1,   Glycolysis↑, 1,   GSK‐3β↓, 2,   HK2↑, 1,   LDHA↑, 1,   LDL↓, 5,   lipidLev↓, 1,   NAD↝, 1,   NADPH↑, 1,   PFKL↑, 1,   PFKM↑, 1,   PFKP↑, 1,   PKM2↑, 1,   SIRT1↑, 7,  

Cell Death(tgid=5) ⓘ

Apoptosis↓, 4,   ASC?, 1,   BAX↓, 2,   Bcl-2↑, 1,   Casp1↓, 1,   Casp3↓, 5,   Casp9↓, 3,   Cyt‑c↓, 2,   Ferroptosis↓, 1,   iNOS↓, 10,   iNOS↑, 1,   p38↓, 3,   Pyro?, 1,   survivin↓, 1,  

Kinase & Signal Transduction(tgid=6) ⓘ

Akt↓, 2,   Akt↑, 1,   AKT1↑, 1,   p‑CREB↑, 1,   ERK↓, 1,   ERK↑, 2,   JAK2↓, 1,   JNK↓, 1,   JNK↑, 1,   p‑JNK↓, 2,   p‑LIMK1↑, 1,   MAPK↓, 4,   MAPK↑, 2,   p‑MEK↑, 1,   mTOR↓, 1,   mTOR↑, 1,   PDGFR-BB↑, 1,   PI3K↓, 1,   PI3K↑, 2,   PKCδ↑, 1,   Sp1/3/4↓, 1,   STAT3↓, 2,  

Transcription & Epigenetics(tgid=7) ⓘ

AntiThr↑, 5,   ATF4↓, 1,   cMyc↓, 2,   HDAC↓, 1,   OCT4↓, 1,   other↓, 4,   other↑, 5,   other↝, 6,   SOX18↑, 1,   SOX9↑, 1,  

Protein Folding & ER Stress(tgid=8) ⓘ

ATF6↓, 1,   CHOP/DDIT3↓, 1,   ER Stress↓, 3,   GRP78/BiP↓, 1,   HSP70/HSPA5↑, 2,   HSPs↑, 1,   PERK↓, 1,  

Autophagy & Lysosomes(tgid=9) ⓘ

Beclin-1/ATG6↓, 1,  

DNA Damage & Repair(tgid=10) ⓘ

DNAdam↓, 4,   P53↓, 1,   PCNA↓, 1,  

Cell Cycle & Senescence(tgid=11) ⓘ

cycD1/CCND1↓, 1,   GADD45A↑, 1,  

Proliferation, Differentiation & Cell State(tgid=12) ⓘ

BMPs↑, 1,   CD133↑, 1,   Diff↑, 1,   FGF↑, 2,   IGF-1↑, 1,   MSCs↑, 1,   neuroG↑, 2,   TumCP↓, 4,   tyrosinase↓, 1,   Wnt↑, 1,  

Migration(tgid=13) ⓘ

AntiAg↑, 8,   Ca+2↓, 2,   Ca+2↑, 1,   Ca+2↝, 2,   p‑Cofilin↑, 1,   COL1↑, 1,   COL2A1↑, 1,   EMT↓, 1,   FAK↑, 1,   ITGB1↑, 1,   p‑MLC2/MYL9↑, 1,   MMP13↓, 1,   MMP2↓, 2,   MMP2↑, 1,   MMP3↓, 1,   MMP9↓, 2,   MMP9↑, 2,   MYPT1 / PPP1R12A↑, 1,   p‑MYPT1 / PPP1R12A↑, 1,   N-cadherin↑, 1,   Rac1↑, 1,   Rho↓, 1,   ROCK1↑, 1,   serineP↓, 1,   Snail↑, 1,   TGF-β↓, 1,   TGF-β↑, 3,   TGF-β1↓, 1,   TIMP1↓, 1,   TIMP2↑, 1,   TumCI↓, 1,   TumCMig↓, 1,   Twist↑, 1,   uPA↓, 1,   Vim↑, 1,   α-SMA↑, 1,   β-catenin/ZEB1↑, 1,  

Angiogenesis & Vasculature(tgid=14) ⓘ

angioG↓, 14,   angioG↑, 28,   angioG↝, 1,   CD31/PECAM-1↑, 1,   E-sel↓, 1,   eNOS↓, 2,   eNOS↑, 2,   Hif1a↓, 2,   Hif1a↑, 4,   NO↓, 8,   NO↑, 2,   VCAM-1↓, 2,   VEGF↓, 8,   VEGF↑, 12,   VEGFR2/KDR/Flk1↑, 1,  

Barriers & Transport(tgid=15) ⓘ

BBB↑, 6,   CLDN5↑, 1,   GastroP↑, 1,   GLUT1↑, 1,   GLUT2↑, 1,   GLUT3↑, 1,   GLUT4↑, 2,   ketosis↑, 1,   MMP↑, 4,   MMP↝, 1,   MMP∅, 1,   OATPs↓, 1,   VGCC↑, 1,   ZO-1↑, 2,  

Immune & Inflammatory Signaling(tgid=16) ⓘ

CD8+↑, 1,   COX1↓, 4,   COX2/PTGS2↓, 23,   CXCR4↓, 1,   ICAM-1↓, 2,   IFN-γ↓, 2,   IL1↓, 1,   IL10↓, 2,   IL10↑, 3,   IL12↓, 1,   IL17↓, 3,   IL18↓, 2,   IL1β↓, 12,   IL2↓, 1,   IL4↓, 1,   IL6↓, 16,   IL6↑, 1,   IL8↓, 1,   Imm↑, 6,   Imm⇅, 1,   Imm↝, 1,   Inflam↓, 87,   Inflam↑, 3,   IRF3↓, 2,   MCP1/CCL2↓, 1,   MyD88↓, 2,   NF-kB↓, 22,   NK cell↑, 1,   NLRP3↓, 3,   p65↓, 1,   PGE2↓, 9,   PGE2↑, 1,   Th1 response↓, 1,   Th2↑, 2,   TLR2↓, 3,   TLR4↓, 3,   TLR4∅, 1,   TNF-α↓, 20,   TNF-α↑, 1,   TRIF↓, 1,   VitD↑, 1,  

Synaptic & Neurotransmission(tgid=18) ⓘ

5HT↑, 1,   AChE↓, 7,   BChE↓, 1,   BDNF↑, 1,   GABA↑, 2,   GABA↝, 1,   MAOA↓, 1,   MAOB↓, 2,   NGF↑, 1,   TrkB↑, 1,  

Protein Aggregation(tgid=19) ⓘ

AGEs↓, 1,   Aβ↓, 9,   BACE/β-secretase↓, 1,   tau↓, 3,   p‑tau↓, 3,   XO↓, 1,  

Hormonal & Nuclear Receptors(tgid=20) ⓘ

Estro↓, 1,   PPARα↑, 1,   PPARγ↓, 1,   PPARγ↑, 2,   testos↑, 1,  

Drug Metabolism & Resistance(tgid=21) ⓘ

BioAv?, 1,   BioAv↓, 27,   BioAv↑, 29,   BioAv⇅, 1,   BioAv↝, 14,   BioAv∅, 1,   BioEnh↑, 2,   CompStab↑, 2,   Dose↑, 1,   Dose⇅, 1,   Dose↝, 8,   Dose∅, 1,   eff↑, 8,   eff↝, 2,   GSTA1↑, 2,   Half-Life↑, 2,   Half-Life↝, 5,   Half-Life∅, 3,   P450↓, 1,   selectivity↑, 1,   Synergy↑, 7,  

Clinical Biomarkers(tgid=22) ⓘ

ALAT?, 1,   ALAT↓, 5,   ALP↓, 2,   ascitic↓, 1,   AST↓, 7,   BloodF↑, 1,   BMD↑, 3,   BP↓, 2,   Calcium↑, 1,   CRP↓, 4,   hs-CRP↓, 1,   IL6↓, 16,   IL6↑, 1,   LDH↓, 4,   Mag↑, 1,   NOS2↓, 1,   TC↓, 1,   VitD↑, 1,  

Functional Outcomes(tgid=23) ⓘ

AntiAge↑, 3,   antiAll↑, 6,   AntiArt↑, 3,   AntiCan↓, 2,   AntiCan↑, 10,   AntiDiabetic↓, 1,   AntiDiabetic↑, 17,   AntiTum↓, 1,   AntiTum↑, 2,   Bone Healing↑, 1,   cardioP↑, 30,   cardioP⇅, 1,   chemoP↑, 3,   chemoPv↑, 3,   ChemoSideEff↓, 2,   cognitive↓, 1,   cognitive↑, 8,   diuretic↑, 1,   fatigue↓, 1,   hepatoP↓, 1,   hepatoP↑, 25,   memory↑, 11,   Mood↑, 1,   motorD↑, 2,   neuroP?, 1,   neuroP↓, 2,   neuroP↑, 43,   Obesity↓, 5,   OS↑, 1,   Pain↓, 3,   PDE4↓, 1,   radioP↑, 3,   RenoP↑, 5,   Risk↓, 2,   Sleep↑, 1,   Stress↓, 1,   Stroke↓, 3,   Stroke↝, 1,   toxicity↓, 31,   toxicity↑, 3,   toxicity↝, 7,   toxicity∅, 8,   Weight↓, 1,   Wound Healing↑, 5,  

Infection & Microbiome(tgid=24) ⓘ

AntiBio↑, 8,   AntiFungal↑, 4,   AntiP↑, 4,   AntiViral↑, 8,   Bacteria↓, 17,   Bacteria↑, 1,   GutMicro↑, 11,   GutMicro↝, 1,   Sepsis↓, 1,  

Ingredients & Constituents(tgid=25) ⓘ

Ingr↑, 1,  
Total Targets: 360

Scientific Paper Hit Count for: angioG, angiogenesis
14 Magnetic Fields
14 Thymoquinone
12 itraconazole
11 Curcumin
11 Chrysin
9 Fisetin
9 Fucoidan
9 MCT, metronomic chemo
9 Resveratrol
9 Sulforaphane (mainly Broccoli)
9 Silymarin (Milk Thistle) silibinin
8 Artemisinin
8 Propolis -bee glue
8 Copper and Cu NanoParticles
8 Kaempferol
8 Quercetin
8 Luteolin
7 Ashwagandha(Withaferin A)
7 Betulinic acid
7 Cinnamon
7 Radiotherapy/Radiation
7 Eugenol
7 Nimbolide
6 Capsaicin
5 Silver-NanoParticles
5 Apigenin (mainly Parsley)
5 Berberine
5 chitosan
5 Ellagic acid
5 EGCG (Epigallocatechin Gallate)
5 Formononetin
5 Gambogic Acid
5 Magnolol
5 Melatonin
5 Selenite (Sodium)
4 immunotherapy
4 Beta-Caryophyllene
4 Boswellia (frankincense)
4 Rosmarinic acid
4 Celastrol
4 D-limonene
4 Disulfiram
4 Isoliquiritigenin
4 Lycopene
4 Phenethyl isothiocyanate
3 Carvacrol
3 Chlorogenic acid
3 Hydroxycinnamic-acid
3 Coenzyme Q10
3 Crocetin
3 Dichloroacetate
3 Emodin
3 Ferulic acid
3 Gallic acid
3 phytic acid, Inositol hexakisphosphate
3 Ivermectin
3 Juglone
3 mebendazole
3 methylseleninic acid
3 Piperlongumine
3 tetrathiomolybdate
2 3-bromopyruvate
2 chemodynamic therapy
2 Allicin (mainly Garlic)
2 Alpha-Lipoic-Acid
2 Chemotherapy
2 beta-glucans
2 Baicalein
2 Boron
2 Caffeic acid
2 Carnosic acid
2 chaetocin
2 Carica papaya leaf extract
2 Cucurbitacin
2 Deguelin
2 Diclofenac
2 Dipyridamole
2 Dandelion Root
2 Ginkgo biloba-EGb 761
2 Flaxseed/Linseed
2 Garcinol
2 Ginkgolide B
2 Helleborus niger extracts – Christmas Rose
2 Honokiol
2 HydroxyTyrosol
2 isoflavones
2 Isovitexin
2 Licochalcone A
2 SDG/lignans
2 Linalool
2 Modified Citrus Pectin
2 Mistletoe/Viscum album Extracts
2 Naringin
2 Piperine
2 Pterostilbene
2 α-Santalol/Sandalwood oil
2 Selenium
2 Selenium NanoParticles
2 Ursolic acid
1 Annona atemoya Seed Extract
1 Auranofin
1 Astragalus
1 Phyllanthus emblica/Emblica officinalis/Amla / Indian Gooseberry
1 Andrographis
1 Anethole/trans-Anethole
1 Aspirin
1 Ascorbyl Palmitate
1 Atorvastatin
1 Aloe anthraquinones
1 Biochanin A
1 Bufalin/Huachansu
1 borneol
1 urea
1 NTP, Non-Thermal Plasma,Cold Atmospheric Plasma
1 Caffeic Acid Phenethyl Ester (CAPE)
1 Sorafenib (brand name Nexavar)
1 Carnosine
1 Celecoxib
1 Centella asiatica / Gotu kola → asiaticoside
1 Chocolate
1 Metformin
1 Citric Acid
1 Vitamin E
1 diet FMD Fasting Mimicking Diet
1 diet Ketogenic
1 Diindolylmethane
1 Zinc
1 Echinacea
1 Electrical Pulses
1 flavonoids
1 olaparib/LYNPARZA
1 Ginkgo biloba
1 Genistein (soy isoflavone)
1 Geraniol
1 Ginger/6-Shogaol/Gingerol
1 Ginkgetin
1 Gossypol/AT-101
1 Hydrogen Gas
1 hydrogen sulfide
1 Hibiscus sabdariffa
1 Hops (Humulus lupulus)
1 isoorientin
1 Vitexin
1 low dose naltrexone
1 Docetaxel
1 Matrine
1 Sulindac
1 Paclitaxel/Taxol
1 Methyl Jasmonate
1 vp16, etoposide
1 Magnetic Field Rotating
1 Lemon Balm/Melissa officinalis
1 Neem
1 Oroxylin-A
1 Oleuropein
1 Oleocanthal
1 Marjoram (Origanum majorana)
1 Oregano
1 Phenylbutyrate
1 Plumbagin
1 Psoralidin
1 Ramucirumab (CYRAMZA)
1 Rutin
1 buckwheat sprouts
1 Salvia officinalis
1 salinomycin
1 Shikonin
1 Theobromine
1 Aflavin-3,3′-digallate
1 Thymol-Thymus vulgaris
1 Urolithin
1 Usnic acid
1 Vitamin C (Ascorbic Acid)
1 Vitamin D3
Query results interpretion may depend on "conditions" listed in the research papers.
Such Conditions may include : 
  -low or high Dose
  -format for product, such as nano of lipid formations
  -different cell line effects
  -synergies with other products 
  -if effect was for normal or cancerous cells

Filter Conditions: Pro/AntiFlg:%  IllCat:%  CanType:%  Cells:%  prod#:%  Target#:447  State#:%  Dir#:%
  wNotes=0  sortOrder:rid,rpid

 

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