Cancer Database Query Results

Scientific Papers found: Click to Expand⟱
4577- AgNPs,    Characterization of Antiplatelet Properties of Silver Nanoparticles
- vitro+vivo, Stroke, NA
*AntiAg↑, *Bacteria↓, *Dose↝, *Dose↝, *Dose↝, *toxicity↝,
4576- AgNPs,    Nanosilver, Next-Generation Antithrombotic Agent
- Study, NA, NA
*AntiAg↑, *Bacteria↓,
4573- AgNPs,    Bioactive silver nanoparticles derived from Carica papaya floral extract and its dual-functioning biomedical application
- in-vitro, Var, MCF-7 - NA, NA, HEK293
toxicity↓, Bacteria↓, selectivity↑,
5147- AgNPs,    Size dependent anti-invasiveness of silver nanoparticles in lung cancer cells
- in-vitro, Lung, A549
TumCMig↓, TumCI↓, ROS↑, p‑NF-kB↑, selectivity↑, eff↝,
5146- AgNPs,    Silver Nanoparticle-Induced Autophagic-Lysosomal Disruption and NLRP3-Inflammasome Activation in HepG2 Cells Is Size-Dependent
- in-vitro, Liver, HepG2
TumAuto↑, EPR↑, LC3B↑, CHOP↑, ER Stress↑, NLRP3↑, Casp1↓,
5145- AgNPs,    Silver nanoparticles induce irremediable endoplasmic reticulum stress leading to unfolded protein response dependent apoptosis in breast cancer cells
- in-vitro, BC, MCF-7 - in-vitro, BC, T47D
Bacteria↓, Apoptosis↑, ER Stress↑, UPR↑, PERK↑, IRE1↑, ATF6↑, ATF4↑, CHOP↑, Casp9↑, Casp7↑, Mcl-1↓, XIAP↓, PARP↝, selectivity↑,
5144- AgNPs,    Differential effects of silver nanoparticles on DNA damage and DNA repair gene expression in Ogg1-deficient and wild type mice
- in-vivo, Nor, NA
*DNAdam↑, *toxicity↝, eff↝,
5143- AgNPs,    Thermal Co-reduction engineered silver nanoparticles induce oxidative cell damage in human colon cancer cells through inhibition of reduced glutathione and induction of mitochondria-involved apoptosis
- in-vitro, CRC, HCT116
ROS↑, lipid-P↑, GSH↓, MMP↓, Casp3↑, Apoptosis↑, TumCCA↑,
5142- AgNPs,    Biosynthesized Protein-Capped Silver Nanoparticles Induce ROS-Dependent Proapoptotic Signals and Prosurvival Autophagy in Cancer Cells
- in-vitro, CRC, HUH7
ROS↑, Apoptosis↑, eff↑, ChemoSen↑, EPR↑, Casp↑, MAPK↑,
888- AgNPs,    Antibacterial Effects of Silver Nanoparticles on the Bacterial Strains Isolated from Catheterized Urinary Tract Infection Cases
- in-vivo, UTI, NA
Bacteria↓,
887- AgNPs,    Antibacterial potential of silver nanoparticles against isolated urinary tract infectious bacterial pathogens
- in-vitro, UTI, NA
Bacteria↓,
328- AgNPs,  Rad,    Silver nanoparticles outperform gold nanoparticles in radiosensitizing U251 cells in vitro and in an intracranial mouse model of glioma
- vitro+vivo, GBM, U251
Apoptosis↑, TumAuto↑,
343- AgNPs,    Silver nanoparticles of different sizes induce a mixed type of programmed cell death in human pancreatic ductal adenocarcinoma
- in-vitro, PC, PANC1
BAX↑, Bcl-2↓, P53↑, TumAuto↑,
342- AgNPs,    Silver nanoparticles; a new hope in cancer therapy?
- Review, NA, NA
ROS↑, DNAdam↑, Apoptosis↑, mtDam↑,
341- AgNPs,    Bioprospecting a native silver-resistant Bacillus safensis strain for green synthesis and subsequent antibacterial and anticancer activities of silver nanoparticles
- in-vitro, Liver, HepG2
TumCD↑, ROS↑,
340- AgNPs,    Screening bioactivities of Caesalpinia pulcherrima L. swartz and cytotoxicity of extract synthesized silver nanoparticles on HCT116 cell line
- in-vitro, CRC, HCT116
TumCD↑,
339- AgNPs,    Cancer cell specific cytotoxic potential of the silver nanoparticles synthesized using the endophytic fungus, Penicillium citrinum CGJ-C2
- in-vitro, BC, MCF-7 - in-vitro, Melanoma, A431 - in-vitro, HCC, HepG2
TumCD↑,
338- AgNPs,    Biogenic silver nanoparticles: In vitro and in vivo antitumor activity in bladder cancer
- vitro+vivo, Bladder, 5637
TumCD↑, Apoptosis↑, TumCMig↓, TumCP↓,
337- AgNPs,  immuno,    Silver nanoparticle induced immunogenic cell death can improve immunotherapy
- Review, NA, NA
PD-L1↓,
336- AgNPs,  PDT,    Photodynamic ability of silver nanoparticles in inducing cytotoxic effects in breast and lung cancer cell lines
- in-vitro, BC, MCF-7
Apoptosis↑,
335- AgNPs,  PDT,    Biogenic Silver Nanoparticles for Targeted Cancer Therapy and Enhancing Photodynamic Therapy
- Review, NA, NA
ROS↑, GSH↓, GPx↑, Catalase↓, SOD↓, p38↑, BAX↑, Bcl-2↓,
334- AgNPs,    Silver-Based Nanoparticles Induce Apoptosis in Human Colon Cancer Cells Mediated Through P53
- in-vitro, Colon, HCT116
Bax:Bcl2↑, P53↑, P21↑, Casp3↑, Casp8↑, Casp9↑, Akt↓, NF-kB↓, DNAdam↑, TumCCA↑,
333- AgNPs,  HPT,    Enhancement effect of cytotoxicity response of silver nanoparticles combined with thermotherapy on C6 rat glioma cells
- in-vivo, GBM, NA
OS↑,
332- AgNPs,  Rad,    Enhancement of Radiosensitization by Silver Nanoparticles Functionalized with Polyethylene Glycol and Aptamer As1411 for Glioma Irradiation Therapy
- in-vivo, GBM, NA
OS↑,
331- AgNPs,  Rad,    Silver nanoparticles: a novel radiation sensitizer for glioma?
- vitro+vivo, GBM, NA
OS↑,
330- AgNPs,  Rad,    Reactive oxygen species acts as executor in radiation enhancement and autophagy inducing by AgNPs
- in-vitro, GBM, U251
TumAuto↑, ROS↑,
329- AgNPs,  Rad,    Enhancement of radiotherapy efficacy by silver nanoparticles in hypoxic glioma cells
- in-vitro, GBM, U251
Apoptosis↑, TumAuto↑,
375- AgNPs,  ALA,    Alpha-Lipoic Acid Prevents Side Effects of Therapeutic Nanosilver without Compromising Cytotoxicity in Experimental Pancreatic Cancer
- in-vitro, PC, Bxpc-3 - in-vitro, PC, PANC1 - in-vitro, PC, MIA PaCa-2 - in-vivo, NA, NA
mtDam↑, ROS↑, *toxicity↓, Dose∅, selectivity↑,
327- AgNPs,  MS-275,    Combination Effect of Silver Nanoparticles and Histone Deacetylases Inhibitor in Human Alveolar Basal Epithelial Cells
- in-vitro, Lung, A549
Apoptosis↑, ROS↑, LDH↓, TNF-α↑, mtDam↑, TumAuto↑, Casp3↑, Casp9↑, DNAdam↑,
326- AgNPs,  TSA,    Modulating chromatin structure and DNA accessibility by deacetylase inhibition enhances the anti-cancer activity of silver nanoparticles
- in-vitro, Cerv, HeLa
Apoptosis↑, ChrMod↝, eff↑,
325- AgNPs,    Silver nanoparticles modulate ABC transporter activity and enhance chemotherapy in multidrug resistant cancer
Apoptosis↑, ABC↓,
324- AgNPs,  CPT,    Silver Nanoparticles Potentiates Cytotoxicity and Apoptotic Potential of Camptothecin in Human Cervical Cancer Cells
- in-vitro, Cerv, HeLa
ROS↑, Casp3↑, Casp9↑, Casp6↑, GSH↓, SOD↓, GPx↓, MMP↓, P53↑, P21↑, Cyt‑c↑, BID↑, BAX↑, Bcl-2↓, Bcl-xL↓, Akt↓, Raf↓, ERK↓, MAP2K1/MEK1↓, JNK↑, p38↑,
322- AgNPs,  Cisplatin,    Heterogeneous Responses of Ovarian Cancer Cells to Silver Nanoparticles as a Single Agent and in Combination with Cisplatin
- in-vitro, Ovarian, A2780S - in-vitro, Ovarian, SKOV3 - in-vitro, Ovarian, OVCAR-3
ROS↑, DNAdam↑, GSH/GSSG↓,
321- AgNPs,    I-131 doping of silver nanoparticles platform for tumor theranosis guided drug delivery
- in-vivo, NA, NA
other↑,
320- AgNPs,    Silver nanoparticles induce endoplasmatic reticulum stress response in zebrafish
- vitro+vivo, NA, HUH7
ROS↑, ER Stress↑, TNF-α↑,
319- AgNPs,    Endoplasmic reticulum stress signaling is involved in silver nanoparticles-induced apoptosis
Apoptosis↑, Ca+2↑, ER Stress↑, PERK↑, IRE1↑, cl‑ATF6↑,
318- AgNPs,    Silver nanoparticles regulate autophagy through lysosome injury and cell hypoxia in prostate cancer cells
- in-vitro, Pca, PC3
lysoM↓, lysosome↓, AMPKα↑, TumAuto↑, mTOR↑,
317- AgNPs,    Autophagic effects and mechanisms of silver nanoparticles in renal cells under low dose exposure
- in-vitro, Kidney, HEK293
TumAuto↑, p62↑,
316- AgNPs,    Endoplasmic reticulum stress: major player in size-dependent inhibition of P-glycoprotein by silver nanoparticles in multidrug-resistant breast cancer cells
- in-vitro, BC, MCF-7
GRP78/BiP↑, ER Stress↑, ROS↑, mtDam↑,
312- AgNPs,  wortm,    Inhibition of autophagy enhances the anticancer activity of silver nanoparticles
- vitro+vivo, Cerv, HeLa
APA↑, p62↓, PIK3CA↑, TumVol↓, TumAuto↑, eff↑,
309- AgNPs,    Interference of silver, gold, and iron oxide nanoparticles on epidermal growth factor signal transduction in epithelial cells
- in-vitro, NA, A431
ROS↑, Akt↓, p‑ERK↓,
306- AgNPs,    Cancer Therapy by Silver Nanoparticles: Fiction or Reality?
- Analysis, NA, NA
EPR↝, ROS↑, IL1↑, IL8↑, ER Stress↑, MMP9↑, MMP↓, Cyt‑c↑, Apoptosis↑, Hif1a↑, BBB↑, GutMicro↝, eff↑, eff↑, RadioS↑,
305- AgNPs,    Activity and pharmacology of homemade silver nanoparticles in refractory metastatic head and neck squamous cell cancer
- Case Report, HNSCC, NA
OS↑, Dose↓, BioAv↝, toxicity↓, Remission↑, other↝, other↝, other↝, Dose↝, BioAv↝,
345- AgNPs,    Antitumor activity of silver nanoparticles in Dalton’s lymphoma ascites tumor model
- vitro+vivo, lymphoma, NA
OS↑, ascitic↓,
344- AgNPs,    Cytotoxicity and ROS production of manufactured silver nanoparticles of different sizes in hepatoma and leukemia cells
- in-vitro, Liver, HepG2
ROS↑, GSH↓,
374- AgNPs,    Silver nanoparticles selectively treat triple‐negative breast cancer cells without affecting non‐malignant breast epithelial cells in vitro and in vivo
- in-vitro, BC, MCF-7 - in-vitro, BC, MDA-MB-231 - in-vivo, NA, NA
ER Stress↑, DNAdam↑, ROS↑, Apoptosis↑, GSH/GSSG↓, NADPH/NADP+↓, TumCG↓, UPR↑,
373- AgNPs,    Cytotoxic Potential and Molecular Pathway Analysis of Silver Nanoparticles in Human Colon Cancer Cells HCT116
- in-vitro, Colon, HCT116
LDH↓, ROS↑, MDA↑, ATP↓, GSH↓, MMP↓,
372- AgNPs,    Investigating oxidative stress and inflammatory responses elicited by silver nanoparticles using high-throughput reporter genes in HepG2 cells: effect of size, surface coating, and intracellular uptake
- in-vitro, Hepat, HepG2
NRF2↑, GSH↓,
371- AgNPs,    Cytotoxicity and genotoxicity of silver nanoparticles in the human lung cancer cell line, A549
- in-vitro, Lung, A549
ROS↑, mtDam↑,
370- AgNPs,    Differential genotoxicity mechanisms of silver nanoparticles and silver ions
- in-vitro, lymphoma, TK6
ROS↑,

Showing Research Papers: 301 to 350 of 6589
Prev Page 7 of 132 Next

* indicates research on normal cells as opposed to diseased cells
Total Research Paper Matches: 6589

Pathway results for Effect on Cancer / Diseased Cells:


Redox & Oxidative Stress

Catalase↓, 1,   GPx↓, 1,   GPx↑, 1,   GSH↓, 6,   GSH/GSSG↓, 2,   lipid-P↑, 1,   MDA↑, 1,   NADPH/NADP+↓, 1,   NRF2↑, 1,   ROS↑, 20,   SOD↓, 2,  

Mitochondria & Bioenergetics

ATP↓, 1,   MMP↓, 4,   mtDam↑, 5,   Raf↓, 1,   XIAP↓, 1,  

Core Metabolism/Glycolysis

LDH↓, 2,   PIK3CA↑, 1,  

Cell Death

Akt↓, 3,   Apoptosis↑, 14,   BAX↑, 3,   Bax:Bcl2↑, 1,   Bcl-2↓, 3,   Bcl-xL↓, 1,   BID↑, 1,   Casp↑, 1,   Casp1↓, 1,   Casp3↑, 4,   Casp6↑, 1,   Casp7↑, 1,   Casp8↑, 1,   Casp9↑, 4,   Cyt‑c↑, 2,   JNK↑, 1,   MAPK↑, 1,   Mcl-1↓, 1,   p38↑, 2,   TumCD↑, 4,  

Kinase & Signal Transduction

AMPKα↑, 1,  

Transcription & Epigenetics

ChrMod↝, 1,   other↑, 1,   other↝, 3,  

Protein Folding & ER Stress

ATF6↑, 1,   cl‑ATF6↑, 1,   CHOP↑, 2,   ER Stress↑, 7,   GRP78/BiP↑, 1,   IRE1↑, 2,   PERK↑, 2,   UPR↑, 2,  

Autophagy & Lysosomes

APA↑, 1,   LC3B↑, 1,   lysoM↓, 1,   lysosome↓, 1,   p62↓, 1,   p62↑, 1,   TumAuto↑, 9,  

DNA Damage & Repair

DNAdam↑, 5,   P53↑, 3,   PARP↝, 1,  

Cell Cycle & Senescence

P21↑, 2,   TumCCA↑, 2,  

Proliferation, Differentiation & Cell State

ERK↓, 1,   p‑ERK↓, 1,   MAP2K1/MEK1↓, 1,   mTOR↑, 1,   TumCG↓, 1,  

Migration

Ca+2↑, 1,   MMP9↑, 1,   TumCI↓, 1,   TumCMig↓, 2,   TumCP↓, 1,  

Angiogenesis & Vasculature

ATF4↑, 1,   EPR↑, 2,   EPR↝, 1,   Hif1a↑, 1,  

Barriers & Transport

BBB↑, 1,  

Immune & Inflammatory Signaling

IL1↑, 1,   IL8↑, 1,   NF-kB↓, 1,   p‑NF-kB↑, 1,   PD-L1↓, 1,   TNF-α↑, 2,  

Protein Aggregation

NLRP3↑, 1,  

Drug Metabolism & Resistance

ABC↓, 1,   BioAv↝, 2,   ChemoSen↑, 1,   Dose↓, 1,   Dose↝, 1,   Dose∅, 1,   eff↑, 5,   eff↝, 2,   RadioS↑, 1,   selectivity↑, 4,  

Clinical Biomarkers

ascitic↓, 1,   GutMicro↝, 1,   LDH↓, 2,   PD-L1↓, 1,  

Functional Outcomes

OS↑, 5,   Remission↑, 1,   toxicity↓, 2,   TumVol↓, 1,  

Infection & Microbiome

Bacteria↓, 4,  
Total Targets: 103

Pathway results for Effect on Normal Cells:


DNA Damage & Repair

DNAdam↑, 1,  

Migration

AntiAg↑, 2,  

Drug Metabolism & Resistance

Dose↝, 3,  

Functional Outcomes

toxicity↓, 1,   toxicity↝, 2,  

Infection & Microbiome

Bacteria↓, 2,  
Total Targets: 6

Query results interpretion may depend on "conditions" listed in the research papers.
Such Conditions may include : 
  -low or high Dose
  -format for product, such as nano of lipid formations
  -different cell line effects
  -synergies with other products 
  -if effect was for normal or cancerous cells
Filter Conditions: Pro/AntiFlg:%  IllCat:%  CanType:%  Cells:%  prod#:%  Target#:%  State#:%  Dir#:%
wNotes=0 sortOrder:rid,rpid

 

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