Dose Cancer Research Results

Dose, Dosage: Click to Expand ⟱
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Type:
Drug dosage vs efficacy, and actual dosage number of research papers.
Scientific Papers found: Click to Expand⟱
5230- Ex,    Effects of an acute maximal exercise bout on serum insulin-like growth factor-1 in adults with MDD
- Trial, Nor, NA
*IGF-1↑, Dose↝,
2143- Ex,    The association between physical activity and bladder cancer: systematic review and meta-analysis
- Review, Bladder, NA
Risk↓, Dose↝,
2144- Ex,    Physical activity, hormone replacement therapy and breast cancer risk: A meta-analysis of prospective studies
- Analysis, NA, NA
Risk↓, Dose?, eff↑,
2145- Ex,    Leisure time physical activity and cancer risk: evaluation of the WHO's recommendation based on 126 high-quality epidemiological studies
- Analysis, Var, NA
Risk↓, Dose↝, eff↑,
2150- Ex,    Roles and molecular mechanisms of physical exercise in cancer prevention and treatment
- Review, Var, NA
eff↓, Dose↝, TumCP↓, Apoptosis↓, ChemoSen↑, chemoP↑,
2149- Ex,    Physical activity and exercise training in cancer patients
- Analysis, Var, NA
eff↑, Dose↑,
4075- FA,    Folic acid, ageing, depression, and dementia
- Review, AD, NA
*Mood↑, *cognitive↑, *other↝, *memory↑, *QoL↑, *homoC↝, *other↝, *Dose↝,
3714- FA,    Recent Advances in the Neuroprotective Properties of Ferulic Acid in Alzheimer's Disease: A Narrative Review
- Review, AD, NA
*antiOx↑, *Inflam↓, *neuroP↑, *NF-kB↓, *NLRP3↓, *iNOS↓, *COX2↓, *TNF-α↓, *IL1β↓, *VCAM-1↓, *ICAM-1↓, *p‑MAPK↓, *p38↓, *JNK↓, *IL6↓, *IL8↓, *hepatoP↑, *RenoP↑, *Catalase↑, *PPARγ↑, *ROS↓, *Fenton↓, *IronCh↑, *SOD↑, *MDA↓, *lipid-P↓, *NRF2↑, *HO-1↑, *ARE↑, *Bil↑, *radioP↑, *GCLC↑, *GCLM↑, *NQO1↑, *Half-Life↝, *GutMicro↑, *Aβ↓, *BDNF↑, *Ca+2↓, *lipid-P↓, *PGE2↓, *cognitive↑, *ChAT↑, *memory↑, *Dose↝, *toxicity↓,
2497- Fenb,    In vitro anti-tubulin effects of mebendazole and fenbendazole on canine glioma cells
- in-vitro, GBM, NA
Dose?, selectivity↑, TumCD↑, α-tubulin↓,
2854- FIS,    New Perspectives for Fisetin
- Review, Var, NA - Review, Stroke, NA
Inflam↓, ChemoSen↑, chemoPv↑, eff↑, memory↑, neuroP↑, *Dose↑, BioAv↓, BBB↑,
2827- FIS,    The Potential Role of Fisetin, a Flavonoid in Cancer Prevention and Treatment
- Review, Var, NA
*antiOx↑, *Inflam↓, neuroP↑, hepatoP↑, RenoP↑, cycD1/CCND1↓, TumCCA↑, MMPs↓, VEGF↓, MAPK↓, NF-kB↓, angioG↓, Beclin-1↑, LC3s↑, ATG5↑, Bcl-2↓, BAX↑, Casp↑, TNF-α↓, Half-Life↓, MMP↓, mt-ROS↑, cl‑PARP↑, CDK2↓, CDK4↓, Cyt‑c↑, Diablo↑, DR5↑, Fas↑, PCNA↓, Ki-67↓, p‑H3↓, chemoP↑, Ca+2↑, Dose↝, CDC25↓, CDC2↓, CHK1↑, Chk2↑, ATM↑, PCK1↓, RAS↓, p‑p38↓, Rho↓, uPA↓, MMP7↓, MMP13↓, GSK‐3β↑, E-cadherin↑, survivin↓, VEGFR2↓, IAP2↓, STAT3↓, JAK1↓, mTORC1↓, mTORC2↓, NRF2↑,
2828- FIS,    Fisetin, a Potent Anticancer Flavonol Exhibiting Cytotoxic Activity against Neoplastic Malignant Cells and Cancerous Conditions: A Scoping, Comprehensive Review
- Review, Var, NA
*neuroP↑, *antiOx↑, *Inflam↓, RenoP↑, COX2↓, Wnt↓, EGFR↓, NF-kB↓, Casp3↑, Ca+2↑, Casp8↑, TumCCA↑, CDK1↓, PI3K↓, Akt↓, mTOR↓, MAPK↓, *P53↓, *P21↓, *p16↓, mTORC1↓, mTORC2↓, P53↑, P21↑, cycD1/CCND1↓, cycA1/CCNA1↓, CDK2↓, CDK4↓, BAX↑, Bcl-2↓, PCNA↓, HER2/EBBR2↓, Cyt‑c↑, MMP↓, cl‑Casp9↑, MMP2↓, MMP9↓, cl‑PARP↑, uPA↓, DR4↑, DR5↑, ROS↓, AIF↑, CDC25↓, Dose↑, CHOP↑, ROS↑, cMyc↓, cardioP↑,
4023- FulvicA,    Shilajit (Mumio) Elicits Apoptosis and Suppresses Cell Migration in Oral Cancer Cells through Targeting Urokinase-type Plasminogen Activator and Its Receptor and Chemokine Signaling Pathways
- in-vitro, Oral, NA
tumCV↓, selectivity↑, Apoptosis↑, uPA↓, TumCMig↓, Dose↝, CXCc↓,
4026- FulvicA,    Shilajitin Cancer Treatment: Probable Mode of Action
- Review, Var, NA
*Inflam↓, *antiOx↑, Dose↝,
4028- FulvicA,    Mineral pitch induces apoptosis and inhibits proliferation via modulating reactive oxygen species in hepatic cancer cells
- in-vitro, Liver, HUH7
Apoptosis↑, TumCP↓, ROS↑, NO↑, Dose↝, MMP↓, Cyt‑c↑, SOD↓, Catalase↓, GSH↑, lipid-P↑, miR-21↓, miR-22↑,
4016- FulvicA,    Shilajit: A Natural Phytocomplex with Potential Procognitive Activity
- Review, AD, NA
*tau↓, *AntiAge↑, *Strength↑, *Dose↝, *BioAv↑, *antiOx↑, *memory↑, *Inflam↓, *cognitive↑, *neuroP↑, *toxicity↝, *toxicity↑,
1624- GA,    Anticancer Effect of Pomegranate Peel Polyphenols against Cervical Cancer
- in-vitro, Cerv, NA
ROS↑, Dose∅, MMP↓, GSH↑,
1954- GamB,    Gambogic acid induces apoptosis in hepatocellular carcinoma SMMC-7721 cells by targeting cytosolic thioredoxin reductase
- in-vitro, HCC, SMMC-7721 cell
AntiTum↑, TrxR↓, TrxR1↓, ROS↑, Apoptosis↑, Dose∅, Dose?,
1955- GamB,    Gambogic acid inhibits thioredoxin activity and induces ROS-mediated cell death in castration-resistant prostate cancer
- in-vitro, Pca, PC3 - in-vitro, Pca, LNCaP - in-vitro, Pca, DU145
ROS↑, Apoptosis↑, Ferroptosis↑, Trx↓, eff↑, TrxR↓, Dose∅, MMP↓, eff↑, Casp↑, NADPH↓, TrxR↓, ChemoSen↑, AR↓,
1636- GAR,    Dangerous dietary supplements: Garcinia cambogia-associated hepatic failure requiring transplantation
- Case Report, Obesity, NA
*Dose∅, *other↑,
3721- Gb,    Ginkgo biloba Extract in Alzheimer’s Disease: From Action Mechanisms to Medical Practice
- Review, AD, NA
*antiOx↑, *ROS↓, *SOD↑, *Catalase↑, *GSR↑, *MMP↑, *Inflam↓, *Aβ↓, *memory↑, *Dose↝, *BBB↑, *neuroP↑,
2465- GI,    Effect of daily ginger consumption on platelet aggregation
- Trial, Nor, NA
AntiAg↝, Dose∅,
4307- H2,    Hydrogen Gas Attenuates Toxic Metabolites and Oxidative Stress-Mediated Signaling to Inhibit Neurodegeneration and Enhance Memory in Alzheimer’s Disease Models
- in-vivo, AD, NA
*cognitive↑, *Inflam↓, *ROS↓, *neuroP↑, *memory↑, *BBB↑, *BDNF↑, *TNF-α↓, *Catalase↑, *IL6↓, *Aβ↓, *GABA↓, *Dose↝,
4308- H2,    A biomimetic upconversion nanoreactors for near-infrared driven H2 release to inhibit tauopathy in Alzheimer's disease therapy
- in-vivo, AD, NA
*BioAv↝, *ROS↓, *p‑tau↓, *Dose↝, *cognitive↑,
2511- H2,    Molecular hydrogen suppresses glioblastoma growth via inducing the glioma stem-like cell differentiation
- in-vivo, GBM, U87MG
TumCG↓, OS↑, CD133↓, Ki-67↓, angioG↓, Diff↑, TumCMig↓, TumCI↓, Dose↝, BBB↑, mt-ROS↑,
2524- H2,    Protective effect of hydrogen-rich water on liver function of colorectal cancer patients treated with mFOLFOX6 chemotherapy
- Trial, NA, NA
hepatoP↑, ALAT↓, AST↓, Dose↝, Dose↝,
2513- H2,    Hydrogen therapy: from mechanism to cerebral diseases
- Review, Stroke, NA
*BBB?, *antiOx↑, *Inflam↓, *Apoptosis↓, *NF-kB↓, *Dose↝,
2512- H2,    Hydrogen Attenuates Allergic Inflammation by Reversing Energy Metabolic Pathway Switch
- in-vivo, asthmatic, NA
selectivity↑, lactateProd↓, ATP↑, HK2↓, PFK↓, Hif1a↓, PGC-1α↑, Glycolysis↓, OXPHOS↑, Dose↝,
2509- H2,    Hydrogen inhibits endometrial cancer growth via a ROS/NLRP3/caspase-1/GSDMD-mediated pyroptotic pathway
- in-vitro, Endo, AN3CA - in-vivo, Endo, NA
selectivity↑, mt-ROS↑, ROS↑, TumW↓, GSDMD↑, Pyro↑, Dose↝, eff↓, TumVol↓,
2506- H2,    Molecular hydrogen suppresses activated Wnt/β-catenin signaling
- in-vivo, Arthritis, NA
*Wnt↓, *β-catenin/ZEB1↓, *Dose↝,
2505- H2,    Hydrogen gas restores exhausted CD8+ T cells in patients with advanced colorectal cancer to improve prognosis
- Trial, CRC, NA
PGC-1α↑, Dose↝, CD8+↑, OS↑,
2504- H2,    Hydrogen gas activates coenzyme Q10 to restore exhausted CD8+ T cells, especially PD-1+Tim3+terminal CD8+ T cells, leading to better nivolumab outcomes in patients with lung cancer
- Trial, Lung, NA
CD8+↑, OS↑, eff↝, CoQ10↑, PDT+↓, PGC-1α↑, Dose↝, *toxicity∅,
2503- H2,    Brain Metastases Completely Disappear in Non-Small Cell Lung Cancer Using Hydrogen Gas Inhalation: A Case Report
- Case Report, Lung, NA
TumVol↓, OS↑, Dose↝, Dose↝, CEA↓, CA125↓, CYFRA21-1↓, SIRT1↓, COX2↓, IL1β↓, IL6↓, TNF-α↓, HMGB1↓, NF-kB↓, EP2↓,
2527- H2,    The healing effect of hydrogen-rich water on acute radiation-induced skin injury in rats
- in-vivo, Wounds, NA
*Dose↝, *SOD↑, *EGF↑, *antiOx↑, *Inflam↓, *Dose↝,
2530- H2,    Improvement of psoriasis-associated arthritis and skin lesions by treatment with molecular hydrogen: A report of three cases
- Case Report, PSA, NA
eff↑, Dose↝, eff↑, IL6↓, eff↑,
3152- H2,  VitC,  Rad,    Hydrogen and Vitamin C Combination Therapy: A Novel Method of Radioprotection
- in-vitro, Nor, HUVECs - in-vivo, NA, NA
AntiTum↑, OS↑, QoL↑, TumVol↓, radioP↑, Dose↑, Dose↝, eff↑,
1631- HCA,    An overview of the safety and efficacy of a novel, natural(-)-hydroxycitric acid extract (HCA-SX) for weight management
- Review, Obesity, NA
*ACLY↓, *toxicity∅, *Dose∅,
1645- HCAs,    Chapter 8 - Hydroxycinnamic Acids: Natural Sources, Biosynthesis, Possible Biological Activities, and Roles in Islamic Medicine
- Review, Nor, NA
Dose∅, ROS⇅, Dose∅,
1641- HCAs,    Lung cancer induced by Benzo(A)Pyrene: ChemoProtective effect of sinapic acid in swiss albino mice
- in-vitro, Lung, A549 - in-vivo, Lung, NA
AntiCan↑, Igs↓, lipid-P↓, ROS↑, Casp3↑, Casp9↑, ChemoSideEff↓, Dose∅,
1643- HCAs,    Mechanisms involved in the anticancer effects of sinapic acid
- Review, Var, NA
*BioAv↓, *toxicity↓, Dose∅, ROS⇅, ROS↑, Igs↑, TumCCA↑, TumAuto↑, eff↑, angioG↓, TumCI↓, TumMeta↓, EMT↓, Vim↓, MMP9↓, MMP2↓, Snail↓, E-cadherin↑, p‑Akt↓, GSK‐3β↓, TumCP↓, ChemoSen↑,
1644- HCAs,  PBG,    Artepillin C (3,5-diprenyl-4-hydroxycinnamic acid) sensitizes LNCaP prostate cancer cells to TRAIL-induced apoptosis
- in-vitro, Pca, LNCaP
NF-kB↓, TRAILR↑, Casp8↑, Casp3↑, MMP↓, Dose?,
2079- HNK,    Honokiol Microemulsion Causes Stage-Dependent Toxicity Via Dual Roles in Oxidation-Reduction and Apoptosis through FoxO Signaling Pathway
- in-vitro, Nor, PC12
*toxicity↝, *ROS↓, *ROS↑, *Dose⇅, *BioAv↑, *BioAv↓, *ROS⇅, *SOD↓, *toxicity↑,
2873- HNK,    Honokiol Alleviates Oxidative Stress-Induced Neurotoxicity via Activation of Nrf2
- in-vitro, Nor, PC12
*neuroP↑, *GSH↑, *HO-1↑, *NADPH↑, *Trx1↑, *TrxR1↑, *NRF2↑, *ROS↓, *antiOx↑, *BBB↑, Dose↓,
2864- HNK,    Honokiol: A Review of Its Anticancer Potential and Mechanisms
- Review, Var, NA
TumCCA↑, CDK2↓, EMT↓, MMPs↓, AMPK↑, TumCI↓, TumCMig↓, TumMeta↓, VEGFR2↓, *antiOx↑, *Inflam↓, *BBB↑, *neuroP↑, *ROS↓, Dose↝, selectivity↑, Casp3↑, Casp9↑, NOTCH1↓, cycD1/CCND1↓, cMyc↓, P21?, DR5↑, cl‑PARP↑, P53↑, Mcl-1↑, p65↓, NF-kB↓, ROS↑, JNK↑, NRF2↑, cJun↑, EF-1α↓, MAPK↓, PI3K↓, mTORC1↓, CSCs↓, OCT4↓, Nanog↓, SOX4↓, STAT3↓, CDK4↓, p‑RB1↓, PGE2↓, COX2↓, β-catenin/ZEB1↑, IKKα↓, HDAC↓, HATs↑, H3↑, H4↑, LC3II↑, c-Raf↓, SIRT3↑, Hif1a↓, ER Stress↑, GRP78/BiP↑, cl‑CHOP↑, MMP↓, PCNA↓, Zeb1↓, NOTCH3↓, CD133↓, Nestin↓, ATG5↑, ATG7↑, survivin↓, ChemoSen↑, SOX2↓, OS↑, P-gp↓, Half-Life↓, Half-Life↝, eff↑, BioAv↓,
3803- Hup,    Huperzine A and Its Neuroprotective Molecular Signaling in Alzheimer’s Disease
- Review, AD, NA
*AChE↓, *neuroP↑, *BBB↑, *Half-Life↑, *cognitive↑, *Dose↝, *BACE↓, *IronCh↑, *TfR1/CD71↓, *ROS↓,
2180- itraC,    Repurposing Drugs in Oncology (ReDO)—itraconazole as an anti-cancer agent
- Review, Var, NA
Dose↝, toxicity↝, BioAv↑, Half-Life↝, BioAv↑, Dose↝, HH↓, TumAuto↑, Akt↓, mTOR↓, angioG↓, MDR1↓, TumCP↓, eff↑,
1917- JG,    Inhibition of human leukemia cells growth by juglone is mediated via autophagy induction, endogenous ROS production, and inhibition of cell migration and invasion
- in-vitro, AML, HL-60
selectivity↑, LC3I↑, LC3II↑, Beclin-1↑, ROS↑, tumCV↓, Dose↝, TumAuto↑,
4011- K+,    Sodium and potassium intakes among US adults: NHANES 2003–2008
- Analysis, NA, NA
*Dose↓, *eff↑, *BP↓,
4005- K+,    Potassium
- Review, Nor, NA - Review, Stroke, NA
*Risk↓, *Dose↝, *Risk↓, *BMD↑, *glucose↓,
1534- LT,  Api,  EGCG,  RES,    Plant polyphenol induced cell death in human cancer cells involves mobilization of intracellular copper ions and reactive oxygen species generation: a mechanism for cancer chemopreventive action
- in-vitro, Nor, MCF10 - in-vitro, BC, MDA-MB-231 - in-vitro, BC, MDA-MB-468 - in-vitro, PC, Bxpc-3
TumCP↓, Apoptosis↑, eff↓, *toxicity↑, Dose?, eff↓, eff↓,

Showing Research Papers: 301 to 350 of 608
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* indicates research on normal cells as opposed to diseased cells
Total Research Paper Matches: 608

Pathway results for Effect on Cancer / Diseased Cells:


Redox & Oxidative Stress ⓘ

Catalase↓, 1,   CoQ10↑, 1,   Ferroptosis↑, 1,   GSH↑, 2,   lipid-P↓, 1,   lipid-P↑, 1,   NRF2↑, 2,   OXPHOS↑, 1,   ROS↓, 1,   ROS↑, 10,   ROS⇅, 2,   mt-ROS↑, 3,   SIRT3↑, 1,   SOD↓, 1,   Trx↓, 1,   TrxR↓, 3,   TrxR1↓, 1,  

Mitochondria & Bioenergetics ⓘ

AIF↑, 1,   ATP↑, 1,   CDC2↓, 1,   CDC25↓, 2,   MMP↓, 7,   PGC-1α↑, 3,   c-Raf↓, 1,  

Core Metabolism/Glycolysis ⓘ

ALAT↓, 1,   AMPK↑, 1,   ATG7↑, 1,   cMyc↓, 2,   Glycolysis↓, 1,   HK2↓, 1,   lactateProd↓, 1,   NADPH↓, 1,   PCK1↓, 1,   PFK↓, 1,   SIRT1↓, 1,  

Cell Death ⓘ

Akt↓, 2,   p‑Akt↓, 1,   Apoptosis↓, 1,   Apoptosis↑, 5,   BAX↑, 2,   Bcl-2↓, 2,   Casp↑, 2,   Casp3↑, 4,   Casp8↑, 2,   Casp9↑, 2,   cl‑Casp9↑, 1,   Chk2↑, 1,   Cyt‑c↑, 3,   Diablo↑, 1,   DR4↑, 1,   DR5↑, 3,   Fas↑, 1,   Ferroptosis↑, 1,   GSDMD↑, 1,   IAP2↓, 1,   JNK↑, 1,   MAPK↓, 3,   Mcl-1↑, 1,   p‑p38↓, 1,   Pyro↑, 1,   survivin↓, 2,   TRAILR↑, 1,   TumCD↑, 1,  

Kinase & Signal Transduction ⓘ

EF-1α↓, 1,   HER2/EBBR2↓, 1,  

Transcription & Epigenetics ⓘ

cJun↑, 1,   H3↑, 1,   p‑H3↓, 1,   H4↑, 1,   HATs↑, 1,   miR-21↓, 1,   tumCV↓, 2,  

Protein Folding & ER Stress ⓘ

CHOP↑, 1,   cl‑CHOP↑, 1,   ER Stress↑, 1,   GRP78/BiP↑, 1,  

Autophagy & Lysosomes ⓘ

ATG5↑, 2,   Beclin-1↑, 2,   LC3I↑, 1,   LC3II↑, 2,   LC3s↑, 1,   TumAuto↑, 3,  

DNA Damage & Repair ⓘ

ATM↑, 1,   CHK1↑, 1,   P53↑, 2,   cl‑PARP↑, 3,   PCNA↓, 3,  

Cell Cycle & Senescence ⓘ

CDK1↓, 1,   CDK2↓, 3,   CDK4↓, 3,   cycA1/CCNA1↓, 1,   cycD1/CCND1↓, 3,   P21?, 1,   P21↑, 1,   p‑RB1↓, 1,   TumCCA↑, 4,  

Proliferation, Differentiation & Cell State ⓘ

CD133↓, 2,   CSCs↓, 1,   Diff↑, 1,   EMT↓, 2,   EP2↓, 1,   GSK‐3β↓, 1,   GSK‐3β↑, 1,   HDAC↓, 1,   HH↓, 1,   mTOR↓, 2,   mTORC1↓, 3,   mTORC2↓, 2,   Nanog↓, 1,   Nestin↓, 1,   NOTCH1↓, 1,   NOTCH3↓, 1,   OCT4↓, 1,   PI3K↓, 2,   RAS↓, 1,   SOX2↓, 1,   STAT3↓, 2,   TumCG↓, 1,   Wnt↓, 1,  

Migration ⓘ

AntiAg↝, 1,   Ca+2↑, 2,   CEA↓, 1,   E-cadherin↑, 2,   Ki-67↓, 2,   miR-22↑, 1,   MMP13↓, 1,   MMP2↓, 2,   MMP7↓, 1,   MMP9↓, 2,   MMPs↓, 2,   Rho↓, 1,   Snail↓, 1,   SOX4↓, 1,   TumCI↓, 3,   TumCMig↓, 3,   TumCP↓, 5,   TumMeta↓, 2,   uPA↓, 3,   Vim↓, 1,   Zeb1↓, 1,   α-tubulin↓, 1,   β-catenin/ZEB1↑, 1,  

Angiogenesis & Vasculature ⓘ

angioG↓, 4,   EGFR↓, 1,   Hif1a↓, 2,   NO↑, 1,   VEGF↓, 1,   VEGFR2↓, 2,  

Barriers & Transport ⓘ

BBB↑, 2,   P-gp↓, 1,  

Immune & Inflammatory Signaling ⓘ

COX2↓, 3,   CXCc↓, 1,   HMGB1↓, 1,   Igs↓, 1,   Igs↑, 1,   IKKα↓, 1,   IL1β↓, 1,   IL6↓, 2,   Inflam↓, 1,   JAK1↓, 1,   NF-kB↓, 5,   p65↓, 1,   PDT+↓, 1,   PGE2↓, 1,   TNF-α↓, 2,  

Hormonal & Nuclear Receptors ⓘ

AR↓, 1,  

Drug Metabolism & Resistance ⓘ

BioAv↓, 2,   BioAv↑, 2,   ChemoSen↑, 5,   Dose?, 5,   Dose↓, 1,   Dose↑, 3,   Dose↝, 23,   Dose∅, 8,   eff↓, 5,   eff↑, 13,   eff↝, 1,   Half-Life↓, 2,   Half-Life↝, 2,   MDR1↓, 1,   selectivity↑, 6,  

Clinical Biomarkers ⓘ

ALAT↓, 1,   AR↓, 1,   AST↓, 1,   CA125↓, 1,   CEA↓, 1,   CYFRA21-1↓, 1,   EGFR↓, 1,   HER2/EBBR2↓, 1,   IL6↓, 2,   Ki-67↓, 2,  

Functional Outcomes ⓘ

AntiCan↑, 1,   AntiTum↑, 2,   cardioP↑, 1,   chemoP↑, 2,   chemoPv↑, 1,   ChemoSideEff↓, 1,   hepatoP↑, 2,   memory↑, 1,   neuroP↑, 2,   OS↑, 6,   QoL↑, 1,   radioP↑, 1,   RenoP↑, 2,   Risk↓, 3,   toxicity↝, 1,   TumVol↓, 3,   TumW↓, 1,  

Infection & Microbiome ⓘ

CD8+↑, 2,  
Total Targets: 209

Pathway results for Effect on Normal Cells:


Redox & Oxidative Stress ⓘ

antiOx↑, 10,   ARE↑, 1,   Bil↑, 1,   Catalase↑, 3,   Fenton↓, 1,   GCLC↑, 1,   GCLM↑, 1,   GSH↑, 1,   GSR↑, 1,   HO-1↑, 2,   lipid-P↓, 2,   MDA↓, 1,   NQO1↑, 1,   NRF2↑, 2,   ROS↓, 8,   ROS↑, 1,   ROS⇅, 1,   SOD↓, 1,   SOD↑, 3,   Trx1↑, 1,   TrxR1↑, 1,  

Metal & Cofactor Biology ⓘ

IronCh↑, 2,   TfR1/CD71↓, 1,  

Mitochondria & Bioenergetics ⓘ

EGF↑, 1,   MMP↑, 1,  

Core Metabolism/Glycolysis ⓘ

ACLY↓, 1,   glucose↓, 1,   homoC↝, 1,   NADPH↑, 1,   PPARγ↑, 1,  

Cell Death ⓘ

Apoptosis↓, 1,   iNOS↓, 1,   JNK↓, 1,   p‑MAPK↓, 1,   p38↓, 1,  

Transcription & Epigenetics ⓘ

other↑, 1,   other↝, 2,  

DNA Damage & Repair ⓘ

p16↓, 1,   P53↓, 1,  

Cell Cycle & Senescence ⓘ

P21↓, 1,  

Proliferation, Differentiation & Cell State ⓘ

IGF-1↑, 1,   Wnt↓, 1,  

Migration ⓘ

Ca+2↓, 1,   VCAM-1↓, 1,   β-catenin/ZEB1↓, 1,  

Barriers & Transport ⓘ

BBB?, 1,   BBB↑, 5,  

Immune & Inflammatory Signaling ⓘ

COX2↓, 1,   ICAM-1↓, 1,   IL1β↓, 1,   IL6↓, 2,   IL8↓, 1,   Inflam↓, 10,   NF-kB↓, 2,   PGE2↓, 1,   TNF-α↓, 2,  

Synaptic & Neurotransmission ⓘ

AChE↓, 1,   BDNF↑, 2,   ChAT↑, 1,   GABA↓, 1,   tau↓, 1,   p‑tau↓, 1,  

Protein Aggregation ⓘ

Aβ↓, 3,   BACE↓, 1,   NLRP3↓, 1,  

Drug Metabolism & Resistance ⓘ

BioAv↓, 2,   BioAv↑, 2,   BioAv↝, 1,   Dose↓, 1,   Dose↑, 1,   Dose⇅, 1,   Dose↝, 12,   Dose∅, 2,   eff↑, 1,   Half-Life↑, 1,   Half-Life↝, 1,  

Clinical Biomarkers ⓘ

Bil↑, 1,   BMD↑, 1,   BP↓, 1,   GutMicro↑, 1,   IL6↓, 2,  

Functional Outcomes ⓘ

AntiAge↑, 1,   cognitive↑, 6,   hepatoP↑, 1,   memory↑, 5,   Mood↑, 1,   neuroP↑, 8,   QoL↑, 1,   radioP↑, 1,   RenoP↑, 1,   Risk↓, 2,   Strength↑, 1,   toxicity↓, 2,   toxicity↑, 3,   toxicity↝, 2,   toxicity∅, 2,  
Total Targets: 96

Scientific Paper Hit Count for: Dose, Dosage
31 Selenium NanoParticles
30 Magnetic Fields
21 Curcumin
19 Resveratrol
18 Silver-NanoParticles
17 Vitamin C (Ascorbic Acid)
16 Selenium
16 Selenite (Sodium)
15 Radiotherapy/Radiation
14 Apigenin (mainly Parsley)
14 Propolis -bee glue
14 Hydrogen Gas
12 Chemotherapy
12 Carvacrol
12 Chlorogenic acid
11 EGCG (Epigallocatechin Gallate)
11 Choline
10 Sulforaphane (mainly Broccoli)
9 Baicalein
8 Auranofin
8 Lycopene
8 Citric Acid
8 Dandelion Root
8 Magnetic Field Rotating
7 3-bromopyruvate
7 Capsaicin
7 chitosan
7 Ellagic acid
7 Electrical Pulses
7 Exercise
7 Silymarin (Milk Thistle) silibinin
7 Whole Body Vibration
6 5-Hydroxytryptophan
6 Astaxanthin
6 Melatonin
6 Hydroxycinnamic-acid
6 nicotinamide adenine dinucleotide
6 Copper and Cu NanoParticles
6 Dichloroacetate
6 SonoDynamic Therapy UltraSound
6 Phenethyl isothiocyanate
5 Alpha-Lipoic-Acid
5 Allicin (mainly Garlic)
5 Acetyl-l-carnitine
5 Metformin
5 Aspirin
5 Boron
5 immunotherapy
5 Spermidine
5 diet FMD Fasting Mimicking Diet
5 Bicarbonate(Sodium)
5 Phenylbutyrate
5 Rosmarinic acid
5 Vitamin D3
5 VitK3,menadione
4 cetuximab
4 Ashwagandha(Withaferin A)
4 Berberine
4 Boswellia (frankincense)
4 Butyrate
4 Caffeic acid
4 Celastrol
4 Chocolate
4 Chrysin
4 Coenzyme Q10
4 Oxygen, Hyperbaric
4 Shilajit/Fulvic Acid
4 Propyl gallate
4 Thymoquinone
3 Astragalus
3 Artemisinin
3 Aloe anthraquinones
3 beta-glucans
3 Bromelain
3 borneol
3 Cat’s Claw
3 Calorie Restriction Mimetics
3 HydroxyCitric Acid
3 Crocetin
3 Disulfiram
3 Eugenol
3 Fisetin
3 Honokiol
3 metronomic chemo
3 Methylsulfonylmethane
3 Piperlongumine
3 Shikonin
3 Aflavin-3,3′-digallate
3 Urolithin
3 Vitamin B1/Thiamine
3 Vitamin E
3 Vitamin K2
2 Glucose
2 almonertinib
2 Bevacizumab (brand Avastin)
2 Anti-oxidants
2 Ascorbyl Palmitate
2 Paclitaxel
2 Atorvastatin
2 Betulinic acid
2 beta-carotene(VitA)
2 Bicalutamide
2 Calcium
2 Sorafenib (brand name Nexavar)
2 Celecoxib
2 Quercetin
2 doxorubicin
2 Garcinol
2 diet Plant based
2 diet Short Term Fasting
2 D-limonene
2 Folic Acid, Vit B9
2 Gambogic Acid
2 Potassium
2 Luteolin
2 capecitabine
2 Iron
2 Niclosamide (Niclocide)
2 probiotics
2 Bifidobacterium
2 Silicic Acid
2 Vitamin B5,Pantothenic Acid
1 5-Aminolevulinic acid
1 Photodynamic Therapy
1 Cisplatin
1 Aromatherapy
1 Baicalin
1 Biochanin A
1 bempedoic acid
1 Bufalin/Huachansu
1 Brucea javanica
1 Bacopa monnieri
1 Bortezomib
1 brusatol
1 Bruteridin(bergamot juice)
1 urea
1 Catechins
1 Cynanbungeigenin C (CBC) and D (CBD)
1 Cannabidiol
1 Chlorophyllin
1 Rutin
1 Cinnamon
1 Carica papaya leaf extract
1 Camptothecin
1 CUSP9
1 Cysteamine
1 diet Ketogenic
1 Docetaxel
1 Lemongrass Extract/Citral
1 Zinc
1 Emodin
1 Ferulic acid
1 Fenbendazole
1 Gallic acid
1 Ginkgo biloba
1 Ginger/6-Shogaol/Gingerol
1 Huperzine A/Huperzia serrata
1 itraconazole
1 Juglone
1 MCToil
1 nivolumab
1 magnetic nanoparticles
1 Mushroom Lion’s Mane
1 Naringin
1 Nimbolide
1 Oleuropein
1 Hyperthermia
1 Phosphatidylserine
1 Pterostilbene
1 Ramucirumab (CYRAMZA)
1 Radio Frequency
1 salinomycin
1 Sulfasalazine
1 irinotecan
1 Taurine
1 Thymol-Thymus vulgaris
1 Ursolic acid
1 Vitamin B6,pyridoxine
1 Vitamin B12
1 Transarterial Chemoembolization
1 Xylitol
Query results interpretion may depend on "conditions" listed in the research papers.
Such Conditions may include : 
  -low or high Dose
  -format for product, such as nano of lipid formations
  -different cell line effects
  -synergies with other products 
  -if effect was for normal or cancerous cells

Filter Conditions: Pro/AntiFlg:%  IllCat:%  CanType:%  Cells:%  prod#:%  Target#:1114  State#:%  Dir#:%
  wNotes=0  sortOrder:rid,rpid

 

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