MMP9 Cancer Research Results

MMP9, MMP9: Click to Expand ⟱
Source: HalifaxProj(suppress)
Type:
Matrix metalloproteinase-9 (MMP-9) is an enzyme that plays a significant role in the degradation of extracellular matrix components.
MMP-9 facilitates the breakdown of the extracellular matrix, which can enable cancer cells to invade surrounding tissues and spread to distant sites (metastasis).
Elevated levels of MMP-9 have been associated with poor prognosis in several cancers, including breast, lung, and colorectal cancers.
MMP2 and MMP9: two enzymes are critical to tumor invasion.
Scientific Papers found: Click to Expand⟱
8569- Matr,    Matrine inhibits the metastatic properties of human cervical cancer cells via downregulating the p38 signaling pathway
- vitro+vivo, Cerv, NA
TumCG↓, Apoptosis↑, TumCI↓, TumCMig↓, MMP2↓, MMP9↓, p38↓, TumCG↓, TumMeta↓,
8570- Matr,    Matrine suppresses invasion of castration-resistant prostate cancer cells by downregulating MMP-2/9 via NF-κB signaling pathway
- vitro+vivo, Pca, DU145 - in-vitro, Pca, PC3
TumCG↓, TumCMig↓, TumCI↓, MMP9↓, MMP2↓, p‑p65↓, NF-kB↓,
8576- Matr,    Matrine reduces the proliferation and invasion of colorectal cancer cells via reducing the activity of p38 signaling pathway
- vitro+vivo, CRC, NA
TumCMig↓, TumCI↓, MMP2↓, MMP9↓, p‑p38↓, TumMeta↓,
8542- Matr,    Matrine Suppresses Lung Cancer Progression via Dual Inhibition of CHEK1-Mediated DNA Damage Repair and PI3K/AKT Survival Signaling
- vitro+vivo, Lung, A549
TumCP↓, TumCMig↓, TumCI↓, TumCCA↑, p‑PI3K↓, CHK1↓, p‑Akt↓, Bcl-2↓, MTA1↓, Vim↓, MMP2↓, MMP9↓, γH2AX↑, E-cadherin↑, BAX↑, cl‑Casp3↑, Ki-67↓, TumCG↓,
8538- Matr,    Matrine suppresses breast cancer cell proliferation and invasion via VEGF-Akt-NF-kappaB signaling
- in-vitro, BC, MDA-MB-231 - ex-vivo, BC, MDA-MB-231
TumCP↓, Synergy↑, Apoptosis?, Bax:Bcl2↑, TumCI↓, MMP9↓, MMP2↓, Akt↓, NF-kB↓, VEGFR1↓, BioAv↝,
8530- Matr,    Matrine inhibits the invasive and migratory properties of human hepatocellular carcinoma by regulating epithelial‑mesenchymal transition
- in-vitro, HCC, NA
TumCP↓, TumCMig↓, TumCI↓, E-cadherin↑, Vim↓, MMP2↓, MMP9↓, Snail↓, Slug↓, EMT↓, PIP3↑, PTEN↑, p‑Akt↓,
8526- Matr,    A Systematic Review of the Pharmacology, Toxicology and Pharmacokinetics of Matrine
- Review, Nor, NA
*AntiCan↑, *Inflam↓, *antiOx↑, *AntiViral↑, *Bacteria↓, *antiAll↑, *Analgesic↑, *hepatoP↑, *cardioP↑, *neuroP↑, *toxicity↝, p38↓, IL6↓, JAK2↓, STAT3↓, Casp↑, PI3K↓, Akt↓, mTOR↓, Beclin-1/ATG6↑, PCNA↓, Bcl-2↓, XIAP↑, VEGF↓, NF-kB↓, MMP2↓, MMP9↓, P-gp/ABCB1↓, survivin↓, OCT4↓, SOX2↓, p62↓, *TNF-α↓, *IL6↓, *HMGB1↓, *AntiArt↑, *NF-kB↓, *IL6↓, *IL8↓, *IL1β↓, *IL17↓, *TNF-α↓, *ROS↓, *NRF2?, *AST↓, *ALAT↓, *TGF-β↓, *α-SMA↓, *JAK2↑, *STAT3↑, *BioAv↝, *Half-Life↝, ChemoSen↑, ATP↓, ROS↑,
8560- Matr,    Matrine: A Promising Natural Product With Various Pharmacological Activities
- Review, AD, NA - Review, Stroke, NA - Review, Var, NA
*antiAll↑, *Stroke↓, *AntiArt↑, TumCCA↑, VEGF↓, Apoptosis↑, P53↑, P21↑, PCNA↓, EIF4E↓, TumCP↓, TumCMig↓, IAP1↓, ROS↑, EMT↓, PAX2↓, ER Stress↑, HK2↓, Apoptosis↑, STAT3↓, mtDam↑, HMGB1↓, ChemoSen↑, p‑GSK‐3β↓, P-gp/ABCB1↓, MRP1/ABCC1↓, Vim↓, cycD1/CCND1↓, CDK4↓, GSH↓, SOD↓, mt-Cyt‑c↓, BAX↑, MMP9↓, MMP2↓, E-cadherin↓, N-cadherin↓, FOXO1↓, FOXO3↓, FOXO4↓, PI3K↓, ATF4↑, CHOP/DDIT3↑, *Aβ↓, *RAGE↓, *memory↑, *Learn↑, *cognitive↑, *MDA↓, *SOD↑, *GPx↑, *Catalase↑, *antiAll↑, *AHR↓, *SOCS-3↓, *ICAM-1↓, *ROS↓, cachexia↓, *BACE/β-secretase↓, *NF-kB↓, *TNF-α↓, *IL1β↓,
8555- Matr,    Matrine Exerts Pharmacological Effects Through Multiple Signaling Pathways: A Comprehensive Review
- Review, Var, NA
*AntiTum↑, *Inflam↓, *Analgesic↑, *AntiViral↑, *Imm↑, *PI3K↑, *Akt↑, *mTOR↑, TumAuto↑, PI3K↓, Akt↓, mTOR↓, Beclin-1/ATG6↑, E-cadherin↑, Vim↓, MMP2↓, MMP9↓, Snail↓, Slug↓, PTEN↑, TumCP↓, TumCMig↓, TumCI↓, ChemoSen↑, ROS↑, uPA↓, p‑ERK↓, cachexia↓, antiD↑, GSK‐3β↓, LC3B-II↑, p62↓, Apoptosis↑, Casp3↑, Casp8↑, Casp9↑, FOXO1↑, FOXO3↑, FOXO4↑, PARP↑, BIM↑, Bcl-2↓, survivin↓, miR-21↓, *HOTAIR↑, *p‑Akt↑, *p‑STAT3↑, *STAT3↑, *ROS↓, Wnt↓, β-catenin/ZEB1↓, NOTCH1↓, JAG1↓, HES1↓, BioAv↝, toxicity↝,
8547- Matr,    Matrine in cancer therapy: antitumor mechanisms and nano-delivery strategies
- Review, Var, NA
*Ingr↝, *AntiTum↑, Apoptosis↑, TumAuto↑, Ferroptosis↑, TumCP↓, TumCMig↓, TumCI↓, JPT1/HN1↓, Erlin1↑, LINC01116↓, miR-592↑, ERK↓, JAK↓, STAT3↓, miR-182-5p↓, PI3K↓, Akt↓, Wnt↓, β-catenin/ZEB1↓, Sharpin↓, ROS↓, AMPK↑, mTOR↓, Snail↓, Vim↓, N-cadherin↓, MMP2↓, MMP9↓, E-cadherin↑, PTEN↑, miR-10b-5p↓, GPx4↓, lipid-P↑, Iron↑, Piezo1↑,
4111- MF,    Coupling of pulsed electromagnetic fields (PEMF) therapy to molecular grounds of the cell
- Review, Arthritis, NA
*Inflam↓, *Cartilage↑, *Pain↓, *QoL↑, *Dose↝, *VEGF↑, *NO↑, *TGF-β↑, *MMP9↓, *PGE2↑, *GPx3↑, *SOD2↑, *Catalase↑, *GSR↑, *Ca+2↑,
3479- MF,    Evaluation of Pulsed Electromagnetic Field Effects: A Systematic Review and Meta-Analysis on Highlights of Two Decades of Research In Vitro Studies
- Review, Var, NA
*eff↓, eff↝, *Hif1a↑, *VEGF↑, *TIMP1↑, *E2Fs↑, *MMP2↑, *MMP9↑, Apoptosis↑,
3481- MF,    No effects of pulsed electromagnetic fields on expression of cell adhesion molecules (integrin, CD44) and matrix metalloproteinase-2/9 in osteosarcoma cell lines
- in-vitro, OS, MG63 - in-vitro, OS, SaOS2
ITGA1∅, ITGB1∅, ITGA5∅, ITGB3∅, ITGB4∅, MMP2∅, MMP9∅, eff↑,
522- MF,    Low Magnetic Field Exposure Alters Prostate Cancer Cell Properties
- in-vitro, Pca, PC3
MMP2↑, MMP9↑, miR-21↑, miR-155↑, miR-210↑, miR-200c↓, miR-126↓,
194- MF,    Electromagnetic Field as a Treatment for Cerebral Ischemic Stroke
- Review, Stroke, NA
*BAD↓, *BAX↓, *Casp3↓, *Bcl-xL↑, *p‑Akt↑, *MMP9↓, *p‑ERK↑, *HIF-1↓, *ROS↓, *VEGF↑, *Ca+2↓, *SOD↑, *IL2↑, *p38↑, *HSP70/HSPA5↑, *Apoptosis↓, *ROS↓, *NO↓,
2311- MFrot,  MF,    Magnetic fields as a potential therapy for diabetic wounds based on animal experiments and clinical trials
- in-vivo, Nor, HaCaT
*COX2/PTGS2↓, *Inflam↓, *MMP9↑, *GPx↑, *Diff↑,
3745- MFrot,  MF,    The neurobiological foundation of effective repetitive transcranial magnetic brain stimulation in Alzheimer's disease
- Review, AD, NA
*neuroP↑, *ROS↓, *Inflam↓, *5HT↑, *cFos↑, *Aβ↓, *memory↑, *BDNF↑, *Ach↑, *AChE↓, *cognitive↑, *BDNF↑, *NGF↑, *β-catenin/ZEB1↑, *p‑Akt↓, *mTOR↓, *MMP1↓, *MMP9↓, *MMP-10↓, *TIMP1↑, *TIMP2↑,
225- MFrot,  MF,    Extremely low frequency magnetic fields regulate differentiation of regulatory T cells: Potential role for ROS-mediated inhibition on AKT
- vitro+vivo, Lung, NA
MMP2↓, MMP9↓, FOXP3↓, ROS↑, p‑Akt↓,
1890- MGO,    The Dual-Role of Methylglyoxal in Tumor Progression – Novel Therapeutic Approaches
- Review, Var, NA
AntiCan?, TumCG↓, GAPDH↓, Apoptosis↑, TumCCA↑, MAPK↑, Bcl-2↓, MMP9↓, ChemoSen↑,
8662- MLT,    Melatonin inhibits bladder tumorigenesis by suppressing PPARγ/ENO1-mediated glycolysis
- vitro+vivo, Bladder, 5637 - in-vitro, CRC, T24/HTB-9 - in-vitro, HNSCC, UM-SCC-1
Glycolysis↓, ENO1↓, ROS↑, TumCP↓, TumMeta↓, TumCCA↑, Casp3↑, BIM↑, Bcl-2↓, γH2AX↑, EMT↓, N-cadherin↓, MMP9↓, Snail↓, Akt↓, eff↓, TumVol↓, PPARγ↓,
8688- MLT,    Melatonin induces apoptosis and cell cycle arrest in cervical cancer cells via inhibition of NF-κB pathway
- in-vitro, Cerv, HeLa - in-vitro, Cerv, SiHa
TumCCA↑, NF-kB↓, COX2/PTGS2↓, MMP9↓, Bcl-2↓, BAX↑,
8675- MLT,    Melatonin combined with antineoplastic drugs or natural products for cancer treatment: An update
- Review, Var, NA
ChemoSen↑, TumCP↓, TumCMig↓, CSCs↓, MDR1↓, chemoP?, IL1β↓, IL6↓, IL8↓, TNF-α↓, COX2/PTGS2↓, iNOS↓, Bcl-2↓, Mcl-1↓, IAP1↓, survivin↓, PCNA↓, Ki-67↓, CC(CDKs/cyclins)↓, TumCMig↓, TumCI↓, Fibronectin↓, Vim↓, N-cadherin↓, MMP2↓, MMP9↓, Synergy↑, Synergy↑, OCT4↓, Nanog↓, ERCC1↓, P-gp/ABCB1↓, EMT↓, Synergy↑, ChemoSen↑,
1782- MLT,    Melatonin in Cancer Treatment: Current Knowledge and Future Opportunities
- Review, Var, NA
AntiCan↑, Apoptosis↑, TumCP↓, TumCG↑, TumMeta↑, ChemoSideEff↓, radioP↑, ChemoSen↑, *ROS↓, *SOD↑, *GSH↑, *GPx↑, *Catalase↑, Dose∅, VEGF↓, Synergy↑, Hif1a↓, GLUT1↑, GLUT3↑, CAIX/CA9↑, P21↑, p27/CDKN1B↑, PTEN↑, Warburg↓, PI3K↓, Akt↓, NF-kB↓, cycD1/CCND1↓, CDK4↓, CycB/CCNB1↓, CDK4↓, MAPK↑, IGF-1R↓, STAT3↓, MMP9↓, MMP2↓, MMP13↓, E-cadherin↑, Vim↓, RANKL↓, JNK↑, Bcl-2↓, P53↑, Casp3↑, Casp9↑, BAX↑, DNArepair↑, COX2/PTGS2↓, IL6↓, IL8↓, NO↓, T-Cell↑, NK cell↑, Treg lymp↓, FOXP3↓, CD4+↑, TNF-α↑, Th1 response↑, BioAv↝, RadioS↑, OS↑,
8906- MOR,    Morin, a avonoid from Moraceae, suppresses growth and invasion of the highly metastatic breast cancer cell line MDA-MB-231 partly through suppression of the Akt pathway
- vitro+vivo, BC, MDA-MB-231
EMT↓, TumCI↓, MMP9↓, ACADS/SCAD↓, p‑Akt↓, AntiTum↓, Dose↝,
8899- MOR,    Morin Inhibits Proliferation, Migration, and Invasion of Bladder Cancer EJ Cells via Modulation of Signaling Pathways, Cell Cycle Regulators, and Transcription Factor-Mediated MMP-9 Expression
- in-vivo, Bladder, NA
TumCP↓, TumCCA↑, cycD1/CCND1↓, cycE/CCNE↓, CDK2↓, CDK4↓, P21↑, p‑ERK↑, p‑JNK↓, p‑Akt↓, TumCMig↓, TumCI↓, MMP9↓, AP-1↓, Sp1/3/4↓, NF-kB↓,
8874- MOR,    The anticarcinogenic and anticancer effects of the dietary flavonoid, morin: Current status, challenges, and future perspectives
- Review, Var, NA
AntiCan↑, selectivity↑, *ROS↓, *Inflam↓, *p‑Akt↓, *NF-kB↓, ChemoSen↑, chemoPv↑, *toxicity↓, BioAv↑, BioAv↓, MRP1/ABCC1↝, BioAv↑, PCNA↓, hepatoP↑, NF-kB↓, TNF-α↓, IL6↓, PGE2↓, MMP2↓, MMP9↓, Apoptosis↑, TNFRSF25/DR3/APO3/LARD/TRAMP/WSL1↑, DR5↑, FasL↑, FADD↑, ROS↑, MMP↓, BAX↑, Bcl-xL↓, Casp9↑, Casp3↑, EMT↓, Akt↓, Hippo↑,
8864- MOR,    Morin, a flavonoid from Moraceae, suppresses growth and invasion of the highly metastatic breast cancer cell line MDA-MB‑231 partly through suppression of the Akt pathway
- vitro+vivo, BC, MDA-MB-231
*antiOx↑, *Inflam↓, *AntiCan↑, TumCA↓, TumCI↓, MMP9↓, N-cadherin↓, EMT↓, p‑Akt↓, Akt↓,
8885- MOR,    Anti-Inflammatory and Anti-Migratory Effects of Morin on Non-Small-Cell Lung Cancer Metastasis via Inhibition of NLRP3/MAPK Signaling Pathway
- in-vitro, Lung, A549 - in-vitro, Lung, H1299
IL1β↓, IL18↓, IL6↓, TumCMig↓, TumCI↓, MMP2↓, MMP9↓, uPAR↓, uPA↓, EMT↓, Fibronectin↓, N-cadherin↓, Vim↓, NLRP3↓, MAPK↓,
8889- MOR,    Selected Flavonols in Breast and Gynecological Cancer: A Systematic Review
- Review, BC, NA - Review, Ovarian, NA
*BioAv↝, *BioAv↝, *Half-Life↓, VCAM-1↓, MMP9↓, N-cadherin↓, p‑Akt↓, Akt↓, TumCMig↓, ChemoSen↑, Gal-3↓,
8860- MOR,    Morin (3,5,7,2',4'-Pentahydroxyflavone) abolishes nuclear factor-kappaB activation induced by various carcinogens and inflammatory stimuli, leading to suppression of nuclear factor-kappaB-regulated gene expression and up-regulation of apoptosis
- in-vitro, Cerv, HeLa - in-vitro, Nor, H4 - in-vitro, Lung, A549
NF-kB↓, IκB↓, survivin↓, Bcl-xL↓, cycD1/CCND1↓, COX2/PTGS2↓, MMP9↓, Akt↓, ChemoSen↑, Synergy↑,
8777- MSM,  Tam,    The combination of methylsulfonylmethane and tamoxifen inhibits the Jak2/STAT5b pathway and synergistically inhibits tumor growth and metastasis in ER-positive breast cancer xenografts
- in-vitro, BC, MCF7 - in-vitro, BC, T47D
tumCV↓, TumCMig↓, JAK2↓, STAT5↓, ChemoSen↑, cycD1/CCND1↓, VEGF↓, IGF-1↓, IGF-1R↓, MMP2↓, MMP3↓, MMP9↓, TumVol↓, STAT3↓,
8944- MushCha,    Inonotus obliquus-derived polysaccharide inhibits the migration and invasion of human non-small cell lung carcinoma cells via suppression of MMP-2 and MMP-9
- in-vitro, Lung, A549
TumCMig↓, TumCI↓, MMP2↓, MMP9↓, p‑MAPK↓, p‑PI3K↓, p‑Akt↓, COX2/PTGS2↓, NF-kB↓,
8937- MushCha,    Effects of Inonotus obliquus Polysaccharides on Proliferation, Invasion, Migration, and Apoptosis of Osteosarcoma Cells
- in-vitro, OS, MG63 - in-vitro, OS, U2OS
Dose↝, TumCP↓, TumCMig↓, TumCI↓, Apoptosis↑, Akt↓, mTOR↓, NF-kB↓, MMP2↓, MMP9↓,
8960- mushLions,    Recent Advances in Erinacine A: Preparation, Biological Activities, and Biosynthetic Pathway
- Review, AD, NA - Review, Park, NA - Review, Stroke, NA
*neuroP↑, *NGF↑, *other↝, *antiOx↑, *Inflam↓, *antiCG↑, *Bacteria↓, *hyperG↝, *AntiDiabetic↑, *AntiCan↑, *neuroG↑, *cognitive↑, *Stroke↓, *IL1β↓, *IL6↓, *TNF-α↓, *RNS↓, *iNOS↓, *MAPK↓, *CHOP/DDIT3↓, TumCD↓, ROS↑, TumCP↓, TumCI↓, ROCK1↓, LIMK2↓, Cofilin↓, PI3K↓, mTOR↓, P70S6K↓, TumCMig↓, TumMeta↓, TGF-β↓, MMP9↓, *AntiAge↑, *RIP1↓, *cl‑Casp8↓, *cl‑Casp3↓, *NRF2↑, *HO-1↑, *SOD1↑,
8952- mushLions,    Induction Apoptosis of Erinacine A in Human Colorectal Cancer Cells Involving the Expression of TNFR, Fas, and Fas Ligand via the JNK/p300/p50 Signaling Pathway With Histone Acetylation
- vitro+vivo, CRC, DLD1
TNFR 1↑, Fas↑, FasL↑, Casp↑, Bcl-2↓, Bcl-xL↓, tumCV↓, selectivity↑, MMP2↓, MMP9↓, Apoptosis↑, Dose↝,
1141- Myr,    Myricetin: targeting signaling networks in cancer and its implication in chemotherapy
- Review, Var, NA
*PI3K↑, *Akt↑, p‑Akt↓, SIRT3↑, p‑ERK↓, p38↓, VEGF↓, MEK↓, MKK4↓, MMP9↓, Raf↓, F-actin↓, MMP2↓, COX2/PTGS2↓, BMP2↓, cycD1/CCND1↓, Bax:Bcl2↑, EMT↓, EGFR↓, TumAuto↑,
1799- NarG,    Naringenin as potent anticancer phytocompound in breast carcinoma: from mechanistic approach to nanoformulations based therapeutics
- Review, BC, NA
TumCCA↑, BioAv↑, Half-Life∅, TNF-α↓, Casp8↑, BAX↑, Bak↑, EGF↓, mTOR↓, PI3K↓, ERK↓, Akt↓, NF-kB↓, VEGF↓, angioG↓, antiOx↑, EMT↓, OS↑, MAPK↓, ChemoSen↑, MMP9↓, MMP2↓, ROS↑, ROS↑, GSH↓, Casp3↑, ROS↑,
1807- NarG,    A Systematic Review of the Preventive and Therapeutic Effects of Naringin Against Human Malignancies
- Review, Var, NA
AntiTum↑, TumCP↓, tumCV↓, TumCCA↑, Mcl-1↓, RAS↓, e-Raf↓, VEGF↓, AntiAg↑, MMP2↓, MMP9↓, TIMP2↑, TIMP1↑, p38↓, Wnt↓, β-catenin/ZEB1↑, Casp↑, P53↑, BAX↑, COX2/PTGS2↓, GLO-I↓, CYP1A1↑, lipid-P↓, p‑Akt↓, p‑mTOR↓, VCAM-1↓, P-gp/ABCB1↓, survivin↓, Bcl-2↓, ROS↑, ROS↑, MAPK↑, STAT3↓, chemoP↑,
1267- NCL,    Niclosamide suppresses migration of hepatocellular carcinoma cells and downregulates matrix metalloproteinase-9 expression
- in-vitro, HCC, NA
TumCP↓, cycD1/CCND1↓, MMP9↓, TumCMig↓,
6491- Nimb,    Nanodelivery and anticancer effect of a limonoid, nimbolide, in breast and pancreatic cancer cells
- Review, PC, NA
eff↑, uPA↓, uPAR↓, p‑EGFR↓, VEGFR1↓, NF-kB↓, IKKα↓, MMP2↓, MMP9↓, TIMP2↑, TumCP↓, IGFR↓, Akt↓, ERK↓, TumCCA↓, BAX↑, BAD↑, FasL⇅, Cyt‑c↑, EPR↑,
6492- Nimb,    Review on Molecular and Chemopreventive Potential of Nimbolide in Cancer
- Review, Var, NA
Apoptosis↑, TumCCA↑, TumCP↓, TumCI↓, angioG↓, TumMeta↓, PTEN↑, NF-kB↓, Wnt↓, β-catenin/ZEB1↓, IKKα↓, CXCR2↓, CXCR4↓, Bcl-2↓, COX2/PTGS2↓, MMP9↓, VEGF↓, TIMP2↑, chemoPv↑, ROS↑, DR4↑, P53↑, BAX↑, Casp3↑, Casp8↑, Casp9↑, cl‑PARP↑, Mcl-1↓, XIAP↓, survivin↓, FasL↑, FADD↑, EGFR↓, MMPs↓,
6486- Nimb,    Nimbolide: promising agent for prevention and treatment of chronic diseases
- Review, Var, NA - Review, AD, NA
*other↝, *Inflam↓, AntiCan↑, *Bacteria↓, *AntiViral↑, *neuroP↑, *hepatoP↑, *ROS?, *NRF2↑, *HO-1↑, *TLR4↓, *NF-kB↓, *AChE↓, *Aβ↓, *GSK‐3β↓, *LDL↓, *DNAdam↓, *lipid-P↓, *antiOx↑, *SOD1↑, *GSH↑, *IL6↓, *IL1β↓, *STAT3↓, *GPx↑, *Catalase↑, *MDA↓, *AntiDiabetic↑, *HDL↓, *MCP1/CCL2↓, *VEGF↓, *MMP9↓, *GutMicro↑, TumCP↓, TumCCA↑, TumCMig↓, NF-kB↓, ROS↑, PI3K↓, Akt↓, mTOR↓, ERK↓, EMT↓, TumMeta↓, ChemoSen↑, eff↑, selectivity↑, CDK4↓, CDK6↓, Wnt↓, β-catenin/ZEB1↓, STAT3↓, MMP2↓, Sp1/3/4↓, AP-1↓, P21↑, *AntiArt↑, *IL23↓, *IL17↓, *IFN-γ↓, *HSP70/HSPA5↓,
6487- Nimb,    Anticancer properties of nimbolide and pharmacokinetic considerations to accelerate its development
- Review, Var, NA
TumCP↓, Apoptosis↓, TumMeta↑, angioG↓, *antiOx↑, *eff↑, Apoptosis↑, MOMP↑, CDK1↓, TumCCA↑, MAPK↓, JAK2↓, STAT3↓, PI3K↓, Akt↓, TumCP↓, *NRF2↑, NF-kB↓, GSK‐3β↑, Wnt↓, β-catenin/ZEB1↓, chemoPv↑, Bcl-xL↓, Bcl-2↓, survivin↓, Cyt‑c↑, BAX↑, BID↑, cl‑Casp↑, P53↑, DR5↑, DR4↑, ROS↑, lipid-P↑, MDA↑, MMP2↓, MMP9↓, uPA↓, ICAM-1↓, CXCR4↓, CXCR2↓, angioG↓, BBB↑,
6493- Nimb,    Nimbolide, a Limonoid Triterpene, Inhibits Growth of Human Colorectal Cancer Xenografts by Suppressing the Proinflammatory Microenvironment
- in-vivo, CRC, HCT116 - vitro+vivo, CRC, HT29
TumCP↓, Apoptosis↑, NF-kB↓, IKKα↓, Bcl-2↓, Bcl-xL↓, survivin↓, Mcl-1↓, cMyc↓, cycD1/CCND1↓, MMP9↓, CXCR4↓, ICAM-1↓, VEGF↓, angioG↓, TumCG↓,
8425- OM,    Anti-metastatic and anti-tumor growth effects of Origanum majorana on highly metastatic human breast cancer cells: inhibition of NFκB signaling and reduction of nitric oxide production
- vitro+vivo, BC, MDA-MB-231
TumCCA↑, Apoptosis↑, E-cadherin↑, TumCMig↓, MMP2↓, MMP9↓, uPAR↓, ICAM-1↓, VEGF↓, p‑IκB↓, NF-kB↓, NO↓, TumCG↓, TumMeta↓,
8452- OM,    Sweet Marjoram: A Review of Ethnopharmacology, Phytochemistry, and Biological Activities
- Review, Nor, NA
*hepatoP↑, *cardioP↑, *AntiAg↑, *GastroP↑, *Bacteria↓, *AntiFungal↑, *Inflam↓, *TumMeta↓, *AntiTum↑, *AChE↓, *Ingr↝, *antiOx↑, Apoptosis↑, P53↑, Bcl-2↓, E-cadherin↑, MMP2↓, MMP9↓, TumMeta↓, *NO↓, *lipid-P↓,
1239- PACs,    Cranberry proanthocyanidins inhibit MMP production and activity
- in-vitro, Nor, NA
*MMPs↓, *MMP1↓, *MMP9↓, *NF-kB↓,
3249- PBG,    Can Propolis Be a Useful Adjuvant in Brain and Neurological Disorders and Injuries? A Systematic Scoping Review of the Latest Experimental Evidence
- Review, Var, NA
*Inflam↓, *ROS↓, *MDA↓, *TNF-α↓, *NO↓, *iNOS↓, *SOD↑, *GPx↑, *GSR↓, *GSH↑, *neuroP↑, *IL6↓, *MMP2↓, *MMP9↓, *MCP1/CCL2↓, *HSP70/HSPA5↑, *motorD↑, *Pain↓, *VCAM-1↓, *NF-kB↓, *MAPK↓, *JNK↓, *IL1β↓, *AChE↓, *toxicity∅, cognitive↑,
3250- PBG,    Allergic Inflammation: Effect of Propolis and Its Flavonoids
- Review, Nor, NA
*SOD↑, *GPx↑, *Catalase↑, *Prx↑, *HO-1↑, *Inflam↓, *TNF-α↓, *IL1β↓, *IL4↑, *IL10↑, *TLR4↓, *LOX1↓, *COX1↓, *COX2/PTGS2↓, *NF-kB↓, *AP-1↓, *ROS↓, *GSH↑, *TGF-β↓, *IL8↓, *MMP9↓, *α-SMA↓, *MDA↓, *antiAll↑,
3257- PBG,    The Potential Use of Propolis as a Primary or an Adjunctive Therapy in Respiratory Tract-Related Diseases and Disorders: A Systematic Scoping Review
- Review, Var, NA
CDK4↓, CDK6↓, pRB↓, ROS↓, TumCCA↑, P21↑, PI3K↓, Akt↓, EMT↓, E-cadherin↑, Vim↓, *COX2/PTGS2↓, *MPO↓, *MDA↓, *TNF-α↓, *IL6↓, *Catalase↑, *SOD↑, *AST↓, *ALAT↓, *IL1β↓, *IL10↓, *GPx↓, *TLR4↓, *Sepsis↓, *IFN-γ↑, *GSH↑, *NRF2↑, *α-SMA↓, *TGF-β↓, *IL5↓, *IL6↓, *IL8↓, *PGE2↓, *NF-kB↓, *MMP9↓,

Showing Research Papers: 301 to 350 of 448
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* indicates research on normal cells as opposed to diseased cells
Total Research Paper Matches: 448

Pathway results for Effect on Cancer / Diseased Cells:


NA, unassigned(tgid=0) ⓘ

NA↓, 1,  

Redox & Oxidative Stress(tgid=1) ⓘ

antiOx↓, 3,   antiOx↑, 10,   antiOx⇅, 1,   Catalase↓, 5,   Catalase↑, 3,   Copper↓, 1,   Copper↑, 1,   frataxin↑, 1,   GPx↓, 2,   GPx↑, 4,   GPx4↓, 6,   GSH↓, 23,   GSH↑, 5,   GSR↑, 2,   GSTs↓, 1,   GSTs↑, 2,   H2O2↓, 1,   H2O2↑, 5,   HO-1↓, 9,   HO-1↑, 14,   HO-2↓, 1,   Iron↑, 3,   Keap1↓, 1,   lipid-P?, 1,   lipid-P↓, 4,   lipid-P↑, 13,   MDA↓, 5,   MDA↑, 5,   MPO↓, 1,   NOX4↓, 1,   NQO1↓, 1,   NQO1↑, 3,   NRF2↓, 13,   NRF2↑, 16,   NRF2⇅, 1,   NRF2↝, 1,   p‑NRF2↓, 1,   Prx↓, 1,   Prx4↑, 1,   PrxII↓, 1,   RNS↑, 1,   ROS?, 2,   ROS↓, 26,   ROS↑, 170,   ROS⇅, 7,   ROS∅, 1,   i-ROS↓, 2,   i-ROS↑, 2,   mt-ROS↑, 1,   SOD↓, 6,   SOD↑, 7,   SOD1↓, 1,   SOD1↑, 2,   SOD2↓, 1,   SOD2↑, 3,   TBARS↑, 1,   Thiols↓, 1,   Trx1↑, 1,   TrxR↓, 7,   xCT/SLC7A11↓, 1,  

Metal & Cofactor Biology(tgid=2) ⓘ

Ferritin↓, 1,   IronCh↑, 2,   Tf↓, 1,   TfR1/CD71↓, 1,  

Mitochondria & Bioenergetics(tgid=3) ⓘ

ADP:ATP↑, 2,   Bfl-1↓, 1,   CDC2↓, 7,   CDC25↓, 10,   compI↓, 1,   compIII↓, 1,   compV↓, 1,   EGF↓, 5,   ETC↓, 3,   mitResp↓, 1,   mitResp↑, 1,   MKK7↓, 1,   mtDam↑, 8,   OCR↓, 3,   mt-OXPHOS↓, 1,   PDH↝, 1,   PINK1↑, 1,   SIRT3↓, 2,   SIRT3↑, 3,  

Core Metabolism/Glycolysis(tgid=4) ⓘ

12LOX↓, 3,   5LO↓, 6,   ACADS/SCAD↓, 1,   ACC↑, 1,   ALAT↓, 6,   ALAT↝, 1,   AMPK↓, 2,   AMPK↑, 20,   AMPK↝, 1,   p‑AMPK↑, 2,   p‑AMT/GCST/T-protein↑, 1,   ATP↓, 13,   mt-ATP↓, 1,   CAIX/CA9↑, 1,   ECAR↓, 1,   ECAR↝, 1,   ENO1↓, 1,   FABP4↑, 1,   FASN↓, 3,   FASN↑, 1,   GAPDH↓, 2,   GLO-I↓, 1,   glucoNG↓, 1,   glucose↓, 1,   GlucoseCon↓, 9,   GlutMet↓, 2,   Glycolysis↓, 23,   GSK‐3β↓, 11,   GSK‐3β↑, 2,   p‑GSK‐3β↓, 3,   HK1↓, 1,   HK2↓, 11,   lactateProd↓, 9,   LDHA↓, 6,   LDL↓, 1,   lipidLev↓, 1,   NADPH↓, 3,   NADPH↑, 3,   O-Glc↓, 1,   PDK1 / PDPK1?, 2,   PDK1 / PDPK1↓, 7,   p‑PDK1 / PDPK1↓, 1,   PDK3↑, 1,   PFK↓, 1,   PIP3↑, 1,   PKM2↓, 8,   PKM2↑, 1,   PLA2↓, 1,   p‑S6↓, 1,   SIRT1↓, 6,   SIRT1↑, 9,   SIRT2↑, 1,   SREBP1/SREBF1↓, 2,   SREBP2↓, 1,   Warburg↓, 4,  

Cell Death(tgid=5) ⓘ

AIF↑, 10,   APAF1↑, 4,   Apoptosis?, 1,   Apoptosis↓, 4,   Apoptosis↑, 143,   ASC↑, 1,   ASK1↑, 1,   BAD↓, 3,   BAD↑, 5,   Bak↑, 5,   BAX↓, 2,   BAX↑, 94,   BAX⇅, 1,   BAX↝, 1,   Bax:Bcl2↑, 22,   Bcl-2↓, 104,   Bcl-2↑, 3,   Bcl-xL↓, 35,   BID↓, 2,   BID↑, 6,   p‑BID↓, 1,   BIM↑, 5,   BNIP3↑, 3,   BNIP3↝, 1,   Casp↓, 1,   Casp↑, 25,   Casp∅, 1,   cl‑Casp↑, 1,   Casp1↓, 1,   Casp1↑, 1,   Casp12?, 1,   Casp12↑, 2,   Casp2↑, 1,   Casp3↓, 5,   Casp3↑, 114,   Casp3∅, 1,   cl‑Casp3↑, 15,   proCasp3↑, 1,   Casp6↑, 1,   Casp7↑, 12,   cl‑Casp7↑, 1,   Casp8↑, 29,   Casp8∅, 1,   cl‑Casp8↑, 4,   proCasp8↑, 2,   Casp9↓, 1,   Casp9↑, 76,   p‑Casp9↑, 1,   cl‑Casp9↑, 8,   proCasp9↓, 1,   proCasp9↑, 1,   cFLIP↓, 4,   Cyt‑c↓, 1,   Cyt‑c↑, 62,   mt-Cyt‑c↓, 1,   Diablo↑, 12,   DR5↑, 22,   Endon↑, 2,   FADD↑, 4,   Fap1↓, 1,   Fas↓, 1,   Fas↑, 20,   FasL↓, 1,   FasL↑, 8,   FasL⇅, 1,   Ferroptosis↑, 7,   GranB/GZMB↝, 1,   GSDME↑, 1,   HEY1↓, 2,   IAP1↓, 16,   IAP2/BIRC3↓, 6,   ICAD↓, 1,   ICD↑, 1,   iNOS↓, 19,   Mcl-1?, 1,   Mcl-1↓, 27,   p‑Mcl-1↓, 1,   MDM2↓, 9,   MDM2↑, 1,   MOMP↑, 2,   Necroptosis↑, 1,   necrosis↑, 2,   NOXA↑, 3,   p38↓, 13,   p38↑, 13,   p‑p38↓, 4,   p‑p38↑, 4,   p‑p38↝, 1,   Perforin↝, 1,   PUMA↓, 1,   PUMA↑, 6,   Pyro↑, 4,   RIP1↑, 1,   RIP3↑, 1,   survivin↓, 53,   TNFR 1↑, 1,   TRAIL↑, 3,   TRAILR↑, 2,   TumCD↓, 1,   TumCD↑, 7,   XIAP↓, 26,   XIAP↑, 1,   YAP/TEAD↓, 5,  

Kinase & Signal Transduction(tgid=6) ⓘ

Akt↓, 134,   Akt↑, 4,   p‑Akt↓, 43,   AKT1↓, 2,   Akt2↓, 1,   CaMKII ↓, 1,   CIP2A↓, 2,   CK2↓, 4,   cMET↓, 2,   p‑cMET↓, 1,   cSrc↓, 3,   EGFR↓, 34,   p‑EGFR↓, 3,   ERK↓, 53,   ERK↑, 8,   p‑ERK↓, 23,   p‑ERK↑, 1,   p‑ERK↝, 1,   FGFR1↓, 3,   FGFR2↓, 1,   FOXD3↑, 2,   HER2/EBBR2↓, 13,   p‑HER2/EBBR2↓, 1,   HGF/c-Met↓, 2,   Hippo↑, 1,   IGF-1R↓, 6,   IGFR↓, 1,   IKKα↓, 10,   IKKα↝, 1,   p‑IKKα↓, 2,   IκB↓, 1,   p‑IκB↓, 3,   p‑IκB↑, 1,   JAK↓, 6,   p‑JAK↓, 1,   JAK1↓, 4,   p‑JAK1↓, 1,   JAK2↓, 17,   p‑JAK2↓, 3,   p‑JAK3↓, 1,   JNK↓, 12,   JNK↑, 18,   p‑JNK↓, 5,   p‑JNK↑, 2,   p‑JNK↝, 1,   p‑MAP2K1/MEK1↓, 1,   MAPK↓, 35,   MAPK↑, 13,   p‑MAPK↓, 2,   MARK4↓, 2,   MEK↓, 5,   p‑MEK↓, 2,   MKK4↓, 1,   mTOR↓, 67,   mTOR↝, 1,   p‑mTOR↓, 11,   mTORC2↓, 2,   mTORC2↑, 1,   p70S6↓, 1,   P70S6K↓, 2,   p‑P70S6K↓, 1,   p‑P90RSK↑, 1,   PDGFR-BB↓, 1,   p‑PDGFR-BB↓, 1,   PDGFRA↓, 1,   PI3K↓, 106,   PI3K↑, 1,   p‑PI3K↓, 8,   p‑PI3K↑, 1,   PI3K/Akt↓, 4,   PKA↓, 2,   PKCδ↓, 14,   p‑PKCδ↓, 1,   PTEN↓, 1,   PTEN↑, 29,   Raf↓, 5,   e-Raf↓, 1,   c-Raf↓, 1,   RAS↓, 12,   p‑S6K↓, 1,   SHP1↑, 2,   Sp1/3/4↓, 12,   Sp1/3/4↑, 1,   Src↓, 2,   p‑Src↓, 1,   STAT↓, 4,   p‑STAT2↓, 1,   STAT3↓, 76,   STAT3↑, 3,   p‑STAT3↓, 13,   p‑STAT3↑, 3,   STAT5↓, 3,   STAT6↓, 2,   TSC2↑, 1,  

Transcription & Epigenetics(tgid=7) ⓘ

ATF3↑, 1,   ATF4↓, 1,   ATF4↑, 6,   ATF4↝, 1,   CBP↓, 1,   cJun↓, 8,   cJun↑, 1,   p‑cJun↓, 1,   cMyc↓, 40,   cMyc↑, 1,   p‑cMyc↑, 1,   DNMT1↓, 6,   DNMTs↓, 7,   EZH2↓, 6,   FOXM1↓, 4,   FOXO↑, 3,   FOXO1↓, 3,   FOXO1↑, 1,   FOXO3↓, 3,   FOXO3↑, 8,   FOXO3↝, 1,   p‑FOXO3↓, 1,   FOXO4↓, 2,   FOXO4↑, 1,   H3↑, 1,   ac‑H3↓, 1,   ac‑H3↑, 2,   H4↑, 1,   ac‑H4↓, 1,   ac‑H4↑, 2,   HATs↓, 7,   HATs↑, 1,   HDAC↓, 18,   HDAC1↓, 5,   HDAC10↓, 1,   HDAC2↓, 3,   HDAC3↓, 2,   HDAC4↓, 1,   HDAC6↓, 2,   HDAC8↓, 1,   HES1↓, 3,   JPT1/HN1↓, 1,   LINC01116↓, 1,   Matr↓, 1,   miR-106b↓, 1,   miR-107↑, 2,   miR-10b-5p↓, 1,   miR-126↓, 1,   miR-133a-3p↑, 1,   miR-139-5p↑, 2,   miR-149↑, 1,   miR-155↓, 5,   miR-155↑, 1,   miR-17↓, 1,   miR-182-5p↓, 1,   miR-194↑, 1,   miR-195↑, 1,   miR-200b↑, 2,   miR-200c↓, 1,   miR-203↑, 1,   miR-21↓, 8,   miR-21↑, 2,   miR-210↑, 1,   miR-221↓, 1,   miR-224↓, 2,   miR-25-5p↑, 1,   miR-27a-3p↓, 1,   miR-27a-3p↑, 1,   miR-301a-3p↓, 1,   miR-340↓, 2,   miR-34a↑, 5,   miR-34b-5p↑, 1,   miR-384↑, 2,   miR-422a↑, 2,   miR-592↑, 1,   MTA2↓, 1,   Myc↓, 5,   n-MYC↓, 2,   NDRG1↑, 1,   OCT4↓, 15,   other↓, 3,   other↑, 1,   other↝, 4,   other∅, 1,   PAX2↓, 1,   PhotoS↑, 1,   SOX2↓, 11,   SOX4↓, 2,   SOX4↑, 1,   SOX9?, 1,   SOX9↓, 2,   SOX9↑, 1,   TCF-4↓, 2,   tumCV↓, 28,   ZBTB10↑, 1,  

Protein Folding & ER Stress(tgid=8) ⓘ

ATF6↑, 1,   CHOP/DDIT3↓, 1,   CHOP/DDIT3↑, 17,   eIF2α↓, 1,   p‑eIF2α↑, 3,   ER Stress↓, 1,   ER Stress↑, 33,   Erlin1↑, 1,   GRP78/BiP↓, 2,   GRP78/BiP↑, 12,   GRP78/BiP↝, 1,   HSF1↓, 1,   HSP27↓, 4,   HSP27↝, 1,   HSP70/HSPA5↓, 7,   HSP70/HSPA5↑, 1,   HSP70/HSPA5↝, 1,   HSP90↓, 11,   HSPs↓, 1,   IRE1↑, 5,   PDI↑, 1,   PERK↑, 3,   Proteasome↓, 1,   SERPINH1/HSP47↓, 1,   UPR↓, 1,   UPR↑, 4,   XBP-1↓, 1,   XBP-1↑, 1,  

Autophagy & Lysosomes(tgid=9) ⓘ

ATG5↓, 1,   ATG5↑, 2,   ATG7↑, 1,   Beclin-1/ATG6↓, 5,   Beclin-1/ATG6↑, 10,   CTSB↓, 2,   CTSD↓, 2,   CTSK↓, 1,   LC3‑Ⅱ/LC3‑Ⅰ↓, 1,   LC3A↑, 1,   LC3B↓, 1,   LC3B-II↓, 1,   LC3B-II↑, 4,   LC3II↓, 3,   LC3II↑, 8,   LC3s↓, 1,   LC3s↑, 1,   p62↓, 6,   p62↑, 2,   PARK2↑, 1,   TumAuto↓, 1,   TumAuto↑, 31,   TumAuto⇅, 1,  

DNA Damage & Repair(tgid=10) ⓘ

ATM?, 1,   ATM↑, 2,   BRCA1↓, 1,   BRCA1↑, 1,   p‑BRCA1↑, 1,   BRCA2↑, 1,   DFF45↓, 2,   DNAdam↓, 3,   DNAdam↑, 40,   DNArepair↓, 2,   DNArepair↑, 1,   ERCC1↓, 1,   ERCC3↑, 1,   hTERT/TERT↓, 11,   MGMT↓, 1,   p16↑, 4,   P53?, 2,   P53↓, 2,   P53↑, 75,   P53↝, 1,   p‑P53↑, 1,   PARP↓, 2,   PARP↑, 16,   cl‑PARP↓, 1,   cl‑PARP↑, 50,   PARP1↑, 1,   PCNA↓, 24,   POLD1↓, 1,   SIRT6↓, 2,   SIRT6↑, 1,   Telomerase↓, 14,   TOP1↓, 7,   TOP2↓, 6,   TOP2↑, 2,   TP53↑, 3,   TRF2↓, 1,   UHRF1↓, 1,   XRCC1↓, 1,   γH2AX↓, 1,   γH2AX↑, 8,   γH2AX↝, 1,  

Cell Cycle & Senescence(tgid=11) ⓘ

CC(CDKs/cyclins)↓, 1,   CDK1↓, 11,   p‑CDK1↓, 1,   CDK1/2/5/9↓, 1,   CDK2↓, 40,   CDK2↑, 3,   CDK4↓, 51,   CDK4↑, 1,   p‑CDK4↓, 1,   CDK4/6↓, 1,   CDK6↓, 24,   CDK6↑, 1,   CDK8↓, 1,   CDKN1C/p57↓, 1,   CDKN1C/p57↑, 1,   CHK1↓, 3,   p‑CHK1↑, 1,   Chk2↓, 2,   Cyc↓, 2,   cycA1/CCNA1↓, 9,   cycA1/CCNA1↑, 2,   CycB/CCNB1↓, 19,   CycB/CCNB1↑, 1,   cycD1/CCND1↓, 85,   cycD1/CCND1↑, 1,   p‑cycD1/CCND1↓, 1,   CycD3↓, 3,   cycE/CCNE↓, 23,   E2Fs↓, 5,   GADD45A↑, 1,   Ki-67↓, 28,   MAD↓, 1,   P21↓, 4,   P21↑, 55,   p27/CDKN1B↓, 2,   p27/CDKN1B↑, 21,   pRB↓, 2,   pRB↑, 1,   p‑pRB↓, 1,   RB1↓, 1,   RB1↑, 2,   p‑RB1↓, 5,   Securin↓, 1,   TumCCA?, 1,   TumCCA↓, 10,   TumCCA↑, 148,  

Proliferation, Differentiation & Cell State(tgid=12) ⓘ

4E-BP1↓, 1,   ALDH↓, 6,   ALDH1A1↓, 3,   BMP2↓, 2,   BMPs↑, 1,   CD133↓, 10,   CD133↑, 1,   CD24↓, 4,   CD34↓, 1,   cFos↓, 8,   p‑cFos↓, 1,   cMYB↓, 1,   CSCs↓, 38,   CSCs↑, 1,   Diff↓, 1,   Diff↑, 3,   EIF4E↓, 1,   FGF↓, 3,   FGF↑, 1,   Gli↓, 2,   Gli1↓, 9,   HH↓, 8,   IGF-1↓, 9,   IGF-2↓, 1,   IGFBP3↓, 1,   IGFBP3↑, 2,   JAG1↓, 1,   Jun↓, 1,   Ki-67↓, 28,   Let-7↑, 6,   LRP6↓, 1,   p‑LRP6↓, 1,   mTORC1↓, 4,   p‑mTORC1↓, 1,   Nanog↓, 11,   Nestin↓, 2,   NICD↓, 1,   NOTCH↓, 19,   NOTCH1↓, 12,   NOTCH1↑, 3,   NOTCH1↝, 1,   NOTCH2↓, 1,   NOTCH3↓, 2,   p300↓, 2,   Piezo1↑, 1,   PTCH1↓, 2,   Shh↓, 7,   Smo↓, 3,   STAT1↓, 1,   p‑STAT1↓, 1,   Sufu↓, 1,   TAZ↓, 1,   TOPflash↓, 1,   TumCG↓, 67,   TumCG↑, 2,   TumCP?, 1,   TumCP↓, 127,   TumCP↑, 2,   tyrosinase↓, 2,   URGCP/URG4↓, 1,   Wnt↓, 42,   Wnt/(β-catenin)↓, 5,   ZFX↓, 1,  

Migration(tgid=13) ⓘ

AEG1↓, 1,   AntiAg?, 1,   AntiAg↓, 1,   AntiAg↑, 2,   AP-1↓, 20,   AP-1↝, 1,   ATPase↓, 1,   AXL↓, 2,   CA↓, 3,   Ca+2↓, 1,   Ca+2↑, 32,   Ca+2↝, 1,   i-Ca+2?, 1,   i-Ca+2↑, 1,   CAFs/TAFs↓, 2,   cal2↓, 1,   CCN2/CTGF↓, 2,   Cdc42↑, 1,   Cofilin↓, 1,   COL1A1↓, 1,   COL3A1↓, 1,   DLC1↑, 1,   E-cadherin↓, 13,   E-cadherin↑, 69,   EMMPRIN↓, 1,   EMT↓, 101,   EMT↑, 3,   EpCAM↓, 4,   F-actin↓, 2,   FAK↓, 22,   FAK↑, 2,   p‑FAK↓, 5,   fascin↓, 1,   Fibronectin↓, 8,   GIT1↓, 1,   GLI2↓, 2,   IQGAP3↓, 1,   ITGA1∅, 1,   ITGA5↓, 3,   ITGA5∅, 1,   ITGB1↓, 4,   ITGB1∅, 1,   ITGB3↓, 1,   ITGB3∅, 1,   ITGB4∅, 1,   KAI1/CD82↑, 1,   LAMs↓, 1,   LIMK2↓, 1,   MALAT1↓, 1,   MET↓, 1,   MMP-10↓, 2,   MMP1↓, 13,   MMP11↓, 1,   MMP13↓, 8,   MMP14↓, 1,   MMP16↓, 3,   MMP2?, 2,   MMP2↓, 260,   MMP2↑, 2,   MMP2⇅, 1,   MMP2↝, 1,   MMP2∅, 1,   MMP3↓, 15,   MMP7↓, 16,   MMP7∅, 1,   MMP9?, 2,   MMP9↓, 399,   MMP9↑, 9,   MMP9⇅, 1,   MMP9↝, 1,   MMP9∅, 1,   pro‑MMP9↓, 1,   MMPs↓, 27,   MTA1↓, 1,   MUC4↓, 2,   N-cadherin↓, 46,   NCAM↓, 1,   PAI-1/SERPINE1↓, 1,   PAK1↓, 2,   PDGF↓, 7,   Rac1↓, 1,   RECK↑, 1,   Rho↓, 6,   ROCK1↓, 7,   ROCK1↑, 1,   Sharpin↓, 1,   Slug?, 1,   Slug↓, 20,   Smad1↓, 1,   Smad1↑, 1,   SMAD2↓, 1,   p‑SMAD2↓, 2,   SMAD3↓, 2,   SMAD3↑, 1,   p‑SMAD3↓, 2,   SMAD4↓, 2,   Snail?, 2,   Snail↓, 37,   Snail↑, 1,   STAC2↓, 1,   TET1↓, 1,   TET1↑, 3,   TGF-β↓, 21,   TGF-β↑, 2,   TGF-β1↓, 1,   TIMP1↓, 7,   TIMP1↑, 23,   TIMP2↓, 5,   TIMP2↑, 17,   TIMP3↑, 2,   TSP-1↑, 3,   TumCA↓, 7,   TumCA↑, 1,   TumCI↓, 135,   TumCI↑, 2,   TumCMig↓, 126,   TumCMig↑, 1,   TumMeta↓, 94,   TumMeta↑, 6,   TumPF↓, 1,   Twist↓, 28,   Twist↑, 1,   uPA↓, 40,   uPAR↓, 7,   Vim?, 1,   Vim↓, 59,   Zeb1↓, 18,   ZEB2↓, 3,   ZEB2↑, 1,   α-SMA↓, 4,   α-SMA↑, 1,   α-tubulin↑, 3,   β-catenin/ZEB1↓, 49,   β-catenin/ZEB1↑, 1,  

Angiogenesis & Vasculature(tgid=14) ⓘ

angioG↓, 97,   angioG↑, 1,   angioS↑, 1,   CCN1/CYR61↓, 1,   CD31/PECAM-1↓, 3,   ECM/TCF↓, 1,   Endoglin↑, 1,   eNOS↓, 3,   HIF-1↓, 4,   Hif1a↓, 57,   Hif1a↑, 2,   Hif1a↝, 1,   LOX1↓, 1,   NO↓, 7,   NO↑, 1,   PHDs↓, 1,   TXA2↓, 1,   VCAM-1↓, 4,   VEGF↓, 148,   VEGF↑, 1,   VEGFR1↓, 5,   VEGFR2/KDR/Flk1↓, 19,  

Barriers & Transport(tgid=15) ⓘ

BBB↑, 4,   BBB∅, 1,   CLDN1↓, 2,   CLDN2↓, 1,   EPR↑, 5,   EPR↝, 1,   GLUT1↓, 9,   GLUT1↑, 1,   GLUT3↑, 1,   GLUT4↓, 1,   MMP↓, 75,   MMP↑, 1,   MMP∅, 1,   MPT↑, 5,   NHE1↓, 2,   TRPM7↓, 1,   TRPV1↑, 3,   ZO-1↑, 4,  

Immune & Inflammatory Signaling(tgid=16) ⓘ

CCR7↓, 1,   CD4+↓, 1,   CD4+↑, 1,   CD44↓, 15,   CD8+↑, 1,   p‑cDC2↓, 1,   COX1↓, 5,   COX2/PTGS2↓, 107,   COX2/PTGS2↑, 2,   COX2/PTGS2↝, 1,   CXCL1↓, 1,   CXCL12↓, 2,   CXCL16↓, 1,   CXCR2↓, 2,   CXCR4↓, 23,   CXCR4↑, 1,   DR4↑, 8,   FOXP3↓, 2,   FOXP3↑, 1,   Gal-3↓, 1,   HMGB1↓, 4,   ICAM-1↓, 12,   IFN-γ↓, 2,   IFN-γ↑, 2,   Igs↑, 1,   IL-1Ra↑, 1,   IL1↓, 7,   IL1↑, 2,   IL10↓, 6,   IL10↑, 3,   IL12↓, 4,   IL12↑, 1,   IL17↓, 1,   IL18↓, 2,   IL18↑, 1,   IL1R2↑, 1,   IL1RL1/ST2↑, 1,   IL1α↓, 2,   IL1β↓, 15,   IL1β↑, 2,   IL2↓, 4,   IL2↑, 4,   IL22↓, 1,   IL23↓, 1,   IL33↑, 1,   IL4↓, 2,   IL4↑, 2,   IL6↓, 53,   IL6↑, 1,   IL8↓, 13,   IL8↑, 2,   Imm↑, 2,   Imm↝, 3,   Inflam↓, 27,   IRAK1↓, 1,   M2 MC↓, 2,   MCP1/CCL2↓, 7,   MIP2↓, 1,   mPGES-1↓, 2,   NF-kB?, 1,   NF-kB↓, 168,   NF-kB↑, 1,   NF-kB↝, 1,   p‑NF-kB↓, 2,   p‑NF-kB↑, 1,   NK cell↑, 3,   NLRP3↓, 3,   NLRP3↑, 2,   p50↓, 3,   p65↓, 11,   p65↑, 1,   p‑p65↓, 3,   PD-1↓, 2,   PD-L1↓, 8,   PD-L1↑, 1,   PGE2↓, 25,   PSA↓, 5,   PSA∅, 1,   RAGE↓, 1,   T-Cell↑, 1,   Th1 response↑, 2,   TLR2↓, 1,   TLR4↓, 3,   TLR4↝, 1,   TNF-α↓, 34,   TNF-α↑, 7,   TNF-α∅, 1,   TNFRSF25/DR3/APO3/LARD/TRAMP/WSL1↑, 1,   TRAF1↓, 1,   Treg lymp↓, 1,  

Cellular Microenvironment(tgid=17) ⓘ

TAMS↝, 1,  

Synaptic & Neurotransmission(tgid=18) ⓘ

5HT↓, 1,   PTN↓, 1,  

Protein Aggregation(tgid=19) ⓘ

XO↓, 1,  

Hormonal & Nuclear Receptors(tgid=20) ⓘ

AhR↓, 1,   AhR↑, 1,   AhR↓, 1,   AR↓, 12,   AR↑, 1,   CYP19↓, 1,   ER-α36↓, 2,   ER(estro)↓, 1,   ERα/ESR1↓, 1,   FGF21↓, 1,   GR↑, 1,   PPARα↓, 2,   PPARα↑, 1,   PPARα↝, 1,   cl‑PPARα↓, 1,   PPARγ↓, 3,   PPARγ↑, 8,   RANKL↓, 2,  

Drug Metabolism & Resistance(tgid=21) ⓘ

BioAv↓, 40,   BioAv↑, 41,   BioAv↝, 10,   BioEnh↑, 2,   CBR1↓, 1,   ChemoSen↓, 2,   ChemoSen↑, 122,   CompStab↓, 1,   CompStab↝, 2,   CYP1A1↓, 3,   CYP1A1↑, 2,   CYP1A2↓, 1,   CYP1B1↑, 1,   DDS↑, 1,   Dose?, 3,   Dose↓, 3,   Dose↑, 6,   Dose↝, 36,   Dose∅, 9,   eff?, 1,   eff↓, 17,   eff↑, 62,   eff↝, 10,   GSTA1↑, 1,   Half-Life↓, 9,   Half-Life↑, 4,   Half-Life↝, 9,   Half-Life∅, 1,   MDR1↓, 7,   MRP1/ABCC1↓, 3,   MRP1/ABCC1↝, 1,   P-gp/ABCB1↓, 17,   P-gp/ABCB1⇅, 1,   P450↓, 1,   RadioS↑, 37,   selectivity?, 2,   selectivity↑, 45,   selectivity∅, 1,   Synergy↑, 88,   TET2↑, 1,  

Clinical Biomarkers(tgid=22) ⓘ

AFP↓, 1,   ALAT↓, 6,   ALAT↝, 1,   ALP↓, 2,   ALP↝, 1,   AR↓, 12,   AR↑, 1,   ascitic↓, 2,   AST↓, 4,   AST↝, 1,   BRCA1↓, 1,   BRCA1↑, 1,   p‑BRCA1↑, 1,   CA125↓, 1,   CRP↓, 3,   E6↓, 2,   E7↓, 2,   EGFR↓, 34,   p‑EGFR↓, 3,   ERα/ESR1↓, 1,   EZH2↓, 6,   Ferritin↓, 1,   FOXM1↓, 4,   HER2/EBBR2↓, 13,   p‑HER2/EBBR2↓, 1,   hTERT/TERT↓, 11,   IL6↓, 53,   IL6↑, 1,   LDH↓, 3,   LDH↑, 4,   Myc↓, 5,   PD-L1↓, 8,   PD-L1↑, 1,   PSA↓, 5,   PSA∅, 1,   RAGE↓, 1,   TP53↑, 3,  

Functional Outcomes(tgid=23) ⓘ

AntiCan↑, 40,   AntiCan?, 1,   antiCG↓, 1,   antiD↑, 1,   AntiDiabetic↑, 2,   antiNeop↑, 3,   AntiTum↓, 1,   AntiTum↑, 19,   cachexia↓, 2,   cardioP↑, 8,   CardioT↑, 2,   chemoP?, 1,   chemoP↑, 16,   chemoPv↑, 18,   ChemoSideEff↓, 4,   cognitive↑, 2,   hepatoP↓, 1,   hepatoP↑, 8,   neuroP↑, 5,   OS↑, 7,   Pin1↓, 1,   QoL↑, 2,   radioP↑, 7,   Remission↑, 1,   RenoP↑, 5,   Risk↓, 4,   toxicity↓, 13,   toxicity↑, 5,   toxicity↝, 6,   toxicity∅, 1,   TumVol↓, 16,   TumVol∅, 1,   TumW↓, 5,   TumW∅, 1,   Weight↑, 1,   Weight∅, 1,   Wound Healing↓, 1,  

Infection & Microbiome(tgid=24) ⓘ

Bacteria↓, 1,   GutMicro↑, 3,   GutMicro↝, 1,   Sepsis↓, 3,  

Ingredients & Constituents(tgid=25) ⓘ

Ingr↝, 1,  
Total Targets: 1037

Pathway results for Effect on Normal Cells:


Redox & Oxidative Stress(tgid=1) ⓘ

antiOx↓, 5,   antiOx↑, 77,   ARE↑, 1,   Catalase↑, 31,   Copper↓, 1,   GPx↓, 1,   GPx↑, 25,   GPx1↑, 1,   GPx3↑, 1,   GPx4↑, 1,   GSH↑, 28,   GSR↓, 1,   GSR↑, 6,   GSTs↑, 11,   H2O2↓, 5,   H2O2∅, 1,   HDL↓, 1,   HDL↑, 2,   HO-1↑, 20,   hyperG↝, 1,   Iron↓, 2,   i-Iron↓, 1,   Keap1↓, 1,   lipid-P↓, 18,   mt-lipid-P↓, 1,   MDA↓, 22,   MPO↓, 3,   MPO↑, 1,   NADH↓, 1,   NQO1↑, 3,   Nrf1↑, 1,   NRF2?, 1,   NRF2↑, 30,   Prx↑, 2,   RNS↓, 4,   ROS?, 2,   ROS↓, 86,   SOD↑, 40,   SOD1↑, 6,   SOD2↑, 3,   TAC↑, 1,   TrxR↑, 1,   xCT/SLC7A11↑, 1,  

Metal & Cofactor Biology(tgid=2) ⓘ

IronCh↑, 4,   Mets↝, 1,  

Mitochondria & Bioenergetics(tgid=3) ⓘ

Insulin↑, 1,   mtDam↓, 1,   PGC-1α↓, 1,   PGC-1α↑, 1,  

Core Metabolism/Glycolysis(tgid=4) ⓘ

12LOX↑, 1,   5LO↓, 3,   ALAT↓, 8,   AMPK↑, 8,   ATP↑, 1,   cAMP↑, 1,   DGAT1↓, 1,   FASN↓, 1,   glucose↓, 1,   glucose↑, 1,   GlucoseCon↑, 2,   GlutMet↑, 1,   GSK‐3β↓, 4,   GSK‐3β↑, 1,   LDL↓, 3,   NAD↑, 1,   NADH:NAD↑, 1,   SIRT1↑, 11,  

Cell Death(tgid=5) ⓘ

Apoptosis↓, 4,   ASC?, 1,   BAD↓, 1,   BAX↓, 7,   Bcl-2↓, 1,   Bcl-2↑, 1,   Bcl-xL↑, 1,   Casp1↓, 1,   Casp3?, 1,   Casp3↓, 7,   Casp3∅, 1,   cl‑Casp3↓, 1,   cl‑Casp8↓, 1,   Casp9↓, 2,   Cyt‑c↓, 3,   Cyt‑c∅, 2,   Ferroptosis↓, 1,   iNOS↓, 14,   iNOS↑, 1,   necrosis↓, 1,   p38↓, 1,   p38↑, 2,   Pyro?, 1,   RIP1↓, 1,  

Kinase & Signal Transduction(tgid=6) ⓘ

Akt↓, 1,   Akt↑, 5,   p‑Akt↓, 2,   p‑Akt↑, 2,   AKT1↓, 1,   CREB↑, 1,   p‑CREB↑, 1,   ERK↓, 1,   ERK↑, 4,   p‑ERK↑, 1,   IGF-1R↓, 1,   JAK↓, 1,   JAK2↑, 1,   JNK↓, 3,   JNK↑, 1,   p‑JNK↓, 1,   p‑LIMK1↑, 1,   MAPK↓, 9,   MAPK↑, 4,   mTOR↓, 1,   mTOR↑, 2,   PDGFR-BB↓, 1,   PI3K↓, 1,   PI3K↑, 5,   PKA↑, 1,   PKCδ↑, 3,   PP2A↑, 1,   PTEN↓, 2,   PTEN↑, 1,   Src↓, 1,   STAT↓, 1,   STAT3↓, 4,   STAT3↑, 2,   p‑STAT3↑, 1,  

Transcription & Epigenetics(tgid=7) ⓘ

AntiThr↑, 3,   cJun↓, 1,   cMyc↓, 1,   p‑cMyc↑, 1,   FOXO↑, 1,   HDAC↓, 1,   HOTAIR↑, 1,   other↓, 4,   other↑, 5,   other↝, 7,   RUNX2↑, 1,  

Protein Folding & ER Stress(tgid=8) ⓘ

CHOP/DDIT3↓, 1,   ER Stress↓, 1,   GRP78/BiP↓, 1,   HSP70/HSPA5↓, 1,   HSP70/HSPA5↑, 7,   HSP70/HSPA5↝, 1,   HSPs↑, 1,   IRE1↓, 1,  

Autophagy & Lysosomes(tgid=9) ⓘ

Beclin-1/ATG6↓, 1,   p62↑, 1,  

DNA Damage & Repair(tgid=10) ⓘ

p‑BRCA1↑, 1,   DNAdam↓, 2,   p16↓, 1,   P53↓, 2,   PCNA↓, 1,  

Cell Cycle & Senescence(tgid=11) ⓘ

CDK2↓, 1,   CDK4↓, 1,   cycD1/CCND1↓, 2,   cycE/CCNE↓, 1,   E2Fs↑, 2,   P21↓, 1,   RB1↓, 1,   TumCCA↑, 1,  

Proliferation, Differentiation & Cell State(tgid=12) ⓘ

BMP2↑, 1,   cFos↑, 1,   Diff↑, 1,   IGF-1↑, 2,   neuroG↑, 3,   TumCP↓, 1,  

Migration(tgid=13) ⓘ

AntiAg↑, 10,   AP-1↓, 4,   Ca+2↓, 1,   Ca+2↑, 1,   Ca+2↝, 1,   Cartilage↑, 1,   p‑Cofilin↑, 1,   COL1↑, 1,   EMT↑, 1,   LAMs↑, 1,   p‑MLC2/MYL9↑, 1,   MMP-10↓, 1,   MMP1↓, 2,   MMP2↓, 7,   MMP2↑, 2,   MMP3↓, 3,   MMP9↓, 32,   MMP9↑, 6,   MMPs↓, 2,   MYPT1 / PPP1R12A↑, 1,   p‑MYPT1 / PPP1R12A↑, 1,   ROCK1↑, 1,   Smad1↑, 1,   SMAD3↓, 1,   TGF-β↓, 4,   TGF-β↑, 2,   TGF-β1↓, 1,   TIMP1↓, 2,   TIMP1↑, 2,   TIMP2↑, 2,   TregCell↑, 1,   TumCI↓, 1,   TumMeta↓, 1,   α-SMA↓, 5,   β-catenin/ZEB1↑, 1,  

Angiogenesis & Vasculature(tgid=14) ⓘ

angioG↓, 1,   angioG↑, 3,   CD31/PECAM-1↓, 1,   eNOS↑, 2,   HIF-1↓, 1,   Hif1a↓, 1,   Hif1a↑, 1,   LOX1↓, 1,   NO↓, 15,   NO↑, 4,   VCAM-1↓, 5,   VEGF↓, 3,   VEGF↑, 6,   p‑VEGFR2/KDR/Flk1↓, 1,  

Barriers & Transport(tgid=15) ⓘ

BBB↓, 2,   BBB↑, 14,   BBB∅, 2,   CLDN1↝, 1,   GastroP↑, 2,   GLUT1↑, 1,   GLUT2↑, 1,   GLUT3↑, 1,   GLUT4↑, 3,   MMP↑, 10,   MMP∅, 1,   MUC19↓, 1,   MUC2↓, 1,   TJ↑, 1,   TRPM7↓, 1,   ZO-1↝, 1,  

Immune & Inflammatory Signaling(tgid=16) ⓘ

CD19↑, 1,   CD4+↑, 1,   COX1↓, 4,   COX2/PTGS2↓, 34,   CXCR4↓, 1,   Eos↓, 1,   HMGB1↓, 2,   ICAM-1↓, 3,   IFN-γ↓, 1,   IFN-γ↑, 1,   IL1↓, 3,   IL10↓, 1,   IL10↑, 5,   IL12↓, 3,   IL17↓, 3,   IL18↓, 2,   IL1β↓, 25,   IL2↑, 2,   IL23↓, 1,   IL4↓, 2,   IL4↑, 2,   IL5↓, 2,   IL6↓, 31,   IL8↓, 7,   Imm↑, 12,   Inflam↓, 85,   Inflam↑, 2,   IRF3↓, 1,   MCP1/CCL2↓, 3,   MyD88↓, 1,   NeuroI↓, 1,   NF-kB↓, 45,   NK cell↑, 1,   NLRP3↓, 6,   NLRP3↑, 1,   p65↓, 1,   PGE2↓, 14,   PGE2↑, 3,   RAGE↓, 1,   SOCS-3↓, 1,   Th1 response↓, 1,   Th2↑, 2,   TLR2↓, 3,   TLR4↓, 6,   TNF-α↓, 32,   TRIF↓, 1,  

Synaptic & Neurotransmission(tgid=18) ⓘ

5HT↑, 2,   Ach↑, 1,   AChE↓, 12,   AChE↑, 1,   BChE↓, 1,   BDNF↑, 9,   GABA↑, 3,   NGF↑, 2,   PSD95↑, 1,   SNAP25↑, 1,  

Protein Aggregation(tgid=19) ⓘ

AGEs↓, 3,   Aβ↓, 15,   BACE/β-secretase↓, 5,   tau↓, 1,   p‑tau↓, 1,   β-Amyloid↓, 1,  

Hormonal & Nuclear Receptors(tgid=20) ⓘ

AHR↓, 1,   CYP19↓, 1,   PPARγ↓, 1,   PPARγ↑, 4,  

Drug Metabolism & Resistance(tgid=21) ⓘ

BioAv↓, 28,   BioAv↑, 25,   BioAv↝, 19,   BioEnh↑, 1,   CompStab↑, 1,   CYP1A1↑, 1,   CYP1A2↑, 1,   CYP2E1↓, 1,   Dose⇅, 1,   Dose↝, 8,   eff↓, 2,   eff↑, 17,   eff↝, 1,   GSTA1↑, 1,   Half-Life↓, 3,   Half-Life↝, 6,   Half-Life∅, 1,   P-gp/ABCB1↓, 1,   P450↓, 3,   Synergy↑, 5,  

Clinical Biomarkers(tgid=22) ⓘ

ALAT↓, 8,   ALP↓, 3,   AST↓, 11,   BMD↑, 1,   BP↓, 2,   BP↝, 1,   p‑BRCA1↑, 1,   CRP↓, 5,   Hcy/homoC↓, 1,   IL6↓, 31,   LDH↓, 4,   LDH↑, 1,   NOS2↓, 2,   RAGE↓, 1,  

Functional Outcomes(tgid=23) ⓘ

Analgesic↑, 2,   AntiAge↑, 4,   antiAll↑, 14,   AntiArt↑, 7,   AntiCan↓, 1,   AntiCan↑, 16,   antiCG↑, 1,   AntiDiabetic↓, 1,   AntiDiabetic↑, 15,   antiPs↑, 1,   AntiTum↑, 5,   cardioP↑, 27,   CardioT↓, 1,   chemoP↑, 4,   chemoPv↑, 3,   cognitive↓, 1,   cognitive↑, 17,   diuretic↑, 3,   hepatoP↓, 1,   hepatoP↑, 24,   Learn↑, 2,   memory↑, 18,   motorD↑, 4,   Mucositis↓, 1,   neuroP↓, 2,   neuroP↑, 61,   Obesity↓, 4,   OS↑, 1,   Pain↓, 6,   QoL↑, 1,   radioP↑, 2,   RenoP↑, 5,   Risk↓, 1,   Stroke↓, 5,   toxicity↓, 20,   toxicity↑, 1,   toxicity↝, 6,   toxicity∅, 3,   Wound Healing↑, 2,  

Infection & Microbiome(tgid=24) ⓘ

AntiBio↑, 2,   AntiFungal↓, 1,   AntiFungal↑, 2,   AntiP↑, 1,   AntiViral↑, 7,   Bacteria↓, 19,   Diar↓, 1,   GutMicro↑, 4,   Sepsis↓, 1,  

Ingredients & Constituents(tgid=25) ⓘ

Ingr↝, 3,  
Total Targets: 379

Scientific Paper Hit Count for: MMP9, MMP9
19 Resveratrol
15 Fisetin
13 Curcumin
12 Thymoquinone
11 Matrine
11 Sulforaphane (mainly Broccoli)
9 Apigenin (mainly Parsley)
9 Baicalein
9 Berberine
9 Quercetin
9 Luteolin
9 Lycopene
8 Garcinol
8 Magnetic Fields
7 Boswellia (frankincense)
7 Propolis -bee glue
7 Capsaicin
7 Magnolol
7 Morin
6 Silver-NanoParticles
6 Alpha-Lipoic-Acid
6 Artemisinin
6 Caffeic acid
6 Chrysin
6 Diindolylmethane
6 Dandelion Root
6 EGCG (Epigallocatechin Gallate)
6 Eugenol
6 Honokiol
6 Kaempferol
6 Rosmarinic acid
5 Melatonin
5 Betulinic acid
5 Ellagic acid
5 Ferulic acid
5 Formononetin
5 Gambogic Acid
5 Nimbolide
5 Piperine
4 Cisplatin
4 Cucurbitacin
4 Pterostilbene
4 Silymarin (Milk Thistle) silibinin
4 Shikonin
4 Urolithin
3 Ascorbyl Palmitate
3 Celastrol
3 Hydroxycinnamic-acid
3 D-limonene
3 Emodin
3 phytic acid, Inositol hexakisphosphate
3 Magnetic Field Rotating
3 Phenethyl isothiocyanate
3 Piperlongumine
2 1,8-Cineole
2 Sorafenib (brand name Nexavar)
2 Astragalus
2 Paclitaxel/Taxol
2 alpha Linolenic acid
2 Radiotherapy/Radiation
2 Ashwagandha(Withaferin A)
2 Baicalin
2 Berbamine
2 Biochanin A
2 Caffeic Acid Phenethyl Ester (CAPE)
2 Carvacrol
2 Thymol-Thymus vulgaris
2 Celecoxib
2 Chlorogenic acid
2 chitosan
2 Cinnamon
2 Crocetin
2 CUSP9
2 Deguelin
2 Indole-3-carbinol
2 Evodiamine
2 tamoxifen
2 Fucoidan
2 Ginkgolic acids
2 Genistein (soy isoflavone)
2 Ginger/6-Shogaol/Gingerol
2 Graviola
2 Grapeseed extract
2 Proanthocyanidins
2 Hibiscus sabdariffa
2 HydroxyTyrosol
2 Inositol
2 Ivermectin
2 Juglone
2 Licorice
2 Mushroom Chaga, Inonotus obliquus
2 Mushroom Lion’s Mane, Hericium erinaceus
2 Naringin
2 Marjoram (Origanum majorana)
2 Selenite (Sodium)
2 Vitamin C (Ascorbic Acid)
1 2-DeoxyGlucose
1 3-bromopyruvate
1 Allicin (mainly Garlic)
1 Phyllanthus emblica/Emblica officinalis/Amla / Indian Gooseberry
1 Andrographis
1 Anethole/trans-Anethole
1 Isovitexin
1 Aspirin
1 Astaxanthin
1 Beta-Caryophyllene
1 Chemotherapy
1 Brucea javanica
1 brusatol
1 Bacopa monnieri
1 borneol
1 Carnosic acid
1 NTP, Non-Thermal Plasma,Cold Atmospheric Plasma
1 Cynanbungeigenin C (CBC) and D (CBD)
1 Centella asiatica / Gotu kola → asiaticoside
1 Selenium NanoParticles
1 Carvone
1 Cyclopamine
1 Cysteamine
1 Vitamin A, Retinoic Acid
1 Folic Acid, Vit B9
1 Bortezomib
1 Flaxseed/Linseed
1 Gallic acid
1 Ginkgo biloba
1 Geraniol
1 Ginkgetin
1 Hops (Humulus lupulus)
1 Hyperoside
1 Isobavachalcone
1 Isoliquiritigenin
1 isoorientin
1 Plumbagin
1 Lactobacillus
1 Licochalcone A
1 Methylglyoxal
1 Methylsulfonylmethane
1 Myricetin
1 Niclosamide (Niclocide)
1 Propyl gallate
1 temozolomide
1 Polyphenols
1 Parthenolide
1 Sanguinarine
1 Sesame seeds and Oil
1 Salvia miltiorrhiza
1 Aflavin-3,3′-digallate
1 Turmerones
1 VitK3,menadione
Query results interpretion may depend on "conditions" listed in the research papers.
Such Conditions may include : 
  -low or high Dose
  -format for product, such as nano of lipid formations
  -different cell line effects
  -synergies with other products 
  -if effect was for normal or cancerous cells

Filter Conditions: Pro/AntiFlg:%  IllCat:%  CanType:%  Cells:%  prod#:%  Target#:203  State#:%  Dir#:%
  wNotes=0  sortOrder:rid,rpid

 

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