MMP9 Cancer Research Results

MMP9, MMP9: Click to Expand ⟱
Source: HalifaxProj(suppress)
Type:
Matrix metalloproteinase-9 (MMP-9) is an enzyme that plays a significant role in the degradation of extracellular matrix components.
MMP-9 facilitates the breakdown of the extracellular matrix, which can enable cancer cells to invade surrounding tissues and spread to distant sites (metastasis).
Elevated levels of MMP-9 have been associated with poor prognosis in several cancers, including breast, lung, and colorectal cancers.
MMP2 and MMP9: two enzymes are critical to tumor invasion.
Scientific Papers found: Click to Expand⟱
3131- VitC,    Antioxidant Vitamin C attenuates experimental abdominal aortic aneurysm development in an elastase-induced rat model
- in-vivo, Nor, NA
*MMP2↓, *MMP9↓, *TNF-α↓, *IL1β↓, *TIMP2↑, *TIMP1↓, *antiOx↑, *Inflam↓,
1820- VitK3,    Vitamin K3 (menadione) suppresses epithelial-mesenchymal-transition and Wnt signaling pathway in human colorectal cancer cells
- in-vitro, CRC, SW480 - in-vitro, CRC, SW-620
selectivity↑, TumCI↓, TumCMig↓, EMT↓, E-cadherin↑, ZO-1↑, N-cadherin↓, Vim↓, Zeb1↓, MMP2↓, MMP9↓, TOPflash↓, β-catenin/ZEB1↓, p300↓, cycD1/CCND1↓, TumCCA↑,

Showing Research Papers: 301 to 302 of 302
Prev Page 7 of 7

* indicates research on normal cells as opposed to diseased cells
Total Research Paper Matches: 302

Pathway results for Effect on Cancer / Diseased Cells:


Cell Cycle & Senescence ⓘ

cycD1/CCND1↓, 1,   TumCCA↑, 1,  

Proliferation, Differentiation & Cell State ⓘ

EMT↓, 1,   p300↓, 1,   TOPflash↓, 1,  

Migration ⓘ

E-cadherin↑, 1,   MMP2↓, 1,   MMP9↓, 1,   N-cadherin↓, 1,   TumCI↓, 1,   TumCMig↓, 1,   Vim↓, 1,   Zeb1↓, 1,   ZO-1↑, 1,   β-catenin/ZEB1↓, 1,  

Drug Metabolism & Resistance ⓘ

selectivity↑, 1,  
Total Targets: 16

Pathway results for Effect on Normal Cells:


Redox & Oxidative Stress ⓘ

antiOx↑, 1,  

Migration ⓘ

MMP2↓, 1,   MMP9↓, 1,   TIMP1↓, 1,   TIMP2↑, 1,  

Immune & Inflammatory Signaling ⓘ

IL1β↓, 1,   Inflam↓, 1,   TNF-α↓, 1,  
Total Targets: 8

Scientific Paper Hit Count for: MMP9, MMP9
18 Resveratrol
14 Fisetin
12 Curcumin
12 Thymoquinone
11 Sulforaphane (mainly Broccoli)
9 Baicalein
9 Berberine
9 Lycopene
8 Apigenin (mainly Parsley)
8 Magnetic Fields
8 Quercetin
7 Boswellia (frankincense)
7 Propolis -bee glue
7 Capsaicin
6 Alpha-Lipoic-Acid
6 Artemisinin
6 Caffeic acid
6 EGCG (Epigallocatechin Gallate)
6 Garcinol
6 Honokiol
6 Rosmarinic acid
5 Silver-NanoParticles
5 Betulinic acid
5 Ellagic acid
5 Magnolol
5 Piperine
4 Cisplatin
4 Chrysin
4 Luteolin
4 Pterostilbene
4 Silymarin (Milk Thistle) silibinin
4 Shikonin
4 Urolithin
3 Ascorbyl Palmitate
3 Celastrol
3 Gambogic Acid
3 Magnetic Field Rotating
3 Phenethyl isothiocyanate
3 Piperlongumine
2 Astragalus
2 Paclitaxel
2 alpha Linolenic acid
2 Radiotherapy/Radiation
2 Ashwagandha(Withaferin A)
2 Melatonin
2 Baicalin
2 Berbamine
2 Biochanin A
2 Caffeic Acid Phenethyl Ester (CAPE)
2 Carvacrol
2 Thymol-Thymus vulgaris
2 Celecoxib
2 Chlorogenic acid
2 chitosan
2 Grapeseed extract
2 Proanthocyanidins
2 Hydroxycinnamic-acid
2 Juglone
2 Naringin
2 Selenite (Sodium)
2 Vitamin C (Ascorbic Acid)
1 2-DeoxyGlucose
1 Sorafenib (brand name Nexavar)
1 3-bromopyruvate
1 Allicin (mainly Garlic)
1 Andrographis
1 Aspirin -acetylsalicylic acid
1 Astaxanthin
1 Chemotherapy
1 Brucea javanica
1 brusatol
1 Bacopa monnieri
1 borneol
1 Carnosic acid
1 Selenium NanoParticles
1 Deguelin
1 Evodiamine
1 Emodin
1 Ferulic acid
1 Genistein (soy isoflavone)
1 Graviola
1 HydroxyTyrosol
1 Plumbagin
1 Methylglyoxal
1 Myricetin
1 Niclosamide (Niclocide)
1 Propyl gallate
1 temozolomide
1 Parthenolide
1 Kaempferol
1 Sanguinarine
1 Sesame seeds and Oil
1 Salvia miltiorrhiza
1 Aflavin-3,3′-digallate
1 VitK3,menadione
Query results interpretion may depend on "conditions" listed in the research papers.
Such Conditions may include : 
  -low or high Dose
  -format for product, such as nano of lipid formations
  -different cell line effects
  -synergies with other products 
  -if effect was for normal or cancerous cells

Filter Conditions: Pro/AntiFlg:%  IllCat:%  CanType:%  Cells:%  prod#:%  Target#:203  State#:%  Dir#:%
  wNotes=0  sortOrder:rid,rpid

 

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