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| Type: |
| Normal cells grow and divide in a regulated manner through the cell cycle, which consists of phases (G1, S, G2, and M). Cancer cells often bypass these regulatory mechanisms, leading to uncontrolled proliferation. This can result from mutations in genes that control the cell cycle, such as oncogenes (which promote cell division) and tumor suppressor genes (which inhibit cell division). |
| 19- | Deg, | Deguelin inhibits proliferation and migration of human pancreatic cancer cells in vitro targeting hedgehog pathway |
| - | in-vitro, | PC, | Bxpc-3 | - | in-vitro, | PC, | PANC1 |
| 1442- | Deg, | Deguelin, a novel anti-tumorigenic agent targeting apoptosis, cell cycle arrest and anti-angiogenesis for cancer chemoprevention |
| - | Review, | Var, | NA |
| 1443- | Deg, | Deguelin Action Involves c-Met and EGFR Signaling Pathways in Triple Negative Breast Cancer Cells |
| - | vitro+vivo, | BC, | MDA-MB-231 | - | in-vitro, | BC, | MDA-MB-435 | - | in-vitro, | BC, | BT549 |
| 1444- | Deg, | Deguelin promotes apoptosis and inhibits angiogenesis of gastric cancer |
| - | in-vitro, | GC, | MKN-28 |
| 1445- | Deg, | Deguelin--an inhibitor to tumor lymphangiogenesis and lymphatic metastasis by downregulation of vascular endothelial cell growth factor-D in lung tumor model |
| - | in-vivo, | lymphoma, | NA | - | in-vitro, | lymphoma, | NA |
| 1446- | Deg, | Efficacy and mechanism of action of Deguelin in suppressing metastasis of 4T1 cells |
| - | in-vitro, | BC, | 4T1 |
| 6708- | DFC, | Repurposing Drugs as Expanding Cancer Treatment Palette: Diclofenac |
| 6692- | DFC, | Diclofenac Inhibits Tumor Growth in a Murine Model of Pancreatic Cancer by Modulation of VEGF Levels and Arginase Activity |
| - | in-vivo, | PC, | Panc02 |
| 6664- | DFE, | Anticancer Properties of Different Varieties of Date Palm (Phoenix dactylifera L.) Leaf Extracts in Human Tumor Cells: a Comparative Study |
| - | in-vitro, | BC, | MDA-MB-231 | - | in-vitro, | GBM, | U87MG |
| 1183- | DHA, | Docosahexaenoic acid inhibited the Wnt/β-catenin pathway and suppressed breast cancer cells in vitro and in vivo |
| - | in-vitro, | BC, | 4T1 | - | in-vitro, | BC, | MCF7 | - | in-vivo, | BC, | NA |
| 6745- | DHA, | Omega-3 fatty acid DHA induces ferroptosis in colorectal cancer patient-derived organoids and drug-tolerant cells |
| - | in-vitro, | CRC, | HT29 |
| 6748- | DHA, | Docosahexaenoic acid enrichment of tumor phospholipid membranes increases tumor necroptosis in mice bearing triple negative breast cancer patient-derived xenografts |
| - | in-vivo, | BC, | NA |
| 6753- | DHA, | Docosahexaenoic Acid (DHA) for Women With Breast Cancer in the Neoadjuvant Setting (DHA-WIN) |
| 1847- | dietFMD, | VitC, | Synergistic effect of fasting-mimicking diet and vitamin C against KRAS mutated cancers |
| - | in-vitro, | PC, | PANC1 |
| 1849- | dietFMD, | The emerging role of fasting-mimicking diets in cancer treatment |
| - | Review, | Var, | NA |
| 1846- | dietFMD, | VitC, | A fasting-mimicking diet and vitamin C: turning anti-aging strategies against cancer |
| - | Study, | Var, | NA |
| 1853- | dietFMD, | Impact of Fasting on Patients With Cancer: An Integrative Review |
| - | Review, | Var, | NA |
| 1857- | dietFMD, | Fasting cycles retard growth of tumors and sensitize a range of cancer cell types to chemotherapy |
| - | in-vitro, | BC, | 4T1 | - | in-vivo, | NA, | NA |
| 1859- | dietFMD, | Chemo, | Fasting-Mimicking Diet Reduces HO-1 to Promote T Cell-Mediated Tumor Cytotoxicity |
| - | in-vitro, | BC, | 4T1 | - | in-vivo, | Melanoma, | B16-BL6 |
| 1860- | dietFMD, | Chemo, | Fasting-mimicking diet blocks triple-negative breast cancer and cancer stem cell escape |
| - | in-vitro, | BC, | SUM159 | - | in-vitro, | BC, | 4T1 |
| 1810- | dietKeto, | Oxy, | The Ketogenic Diet and Hyperbaric Oxygen Therapy Prolong Survival in Mice with Systemic Metastatic Cancer |
| - | in-vivo, | Var, | NA |
| 1897- | dietMet, | Methionine metabolism in health and cancer: a nexus of diet and precision medicine |
| - | Review, | Var, | NA |
| 1896- | dietMet, | Dietary methionine links nutrition and metabolism to the efficacy of cancer therapies |
| - | in-vivo, | CRC, | NA |
| 1893- | dietMet, | Clinical Studies of Methionine-Restricted Diets for Cancer Patients |
| - | Review, | Var, | NA |
| 2263- | dietMet, | Methionine Restriction and Cancer Biology |
| - | Review, | Var, | NA |
| 2267- | dietMet, | Role of amino acids in regulation of ROS balance in cancer |
| - | Review, | Var, | NA |
| 5188- | dietMet, | Dietary methionine links nutrition and metabolism to the efficacy of cancer therapies |
| - | in-vivo, | Var, | NA |
| 2157- | dietP, | Plant-Based Diets and Disease Progression in Men With Prostate Cancer |
| - | Study, | Pca, | NA |
| 1626- | dietSTF, | dietFMD, | When less may be more: calorie restriction and response to cancer therapy |
| - | Review, | Var, | NA |
| 5071- | dietSTF, | Unraveling the impact of intermittent fasting in cancer prevention, mitigation, and treatment: A narrative review |
| - | Review, | Var, | NA | - | Review, | AD, | NA |
| 6729- | Dipy, | Dipyridamole prevents triple-negative breast-cancer progression |
| - | Trial, | BC, | MDA-MB-231 |
| 6730- | Dipy, | ASA, | Dipyridamole enhances the anti-cancer ability of aspirin against colorectal cancer by inducing apoptosis in an unfolded protein response-dependent manner |
| - | vitro+vivo, | CRC, | NA |
| 4984- | Dipy, | ATV, | Immediate Utility of Two Approved Agents to Target Both the Metabolic Mevalonate Pathway and Its Restorative Feedback Loop |
| - | in-vitro, | AML, | NA |
| 6270- | DL, | d-limonene exhibits antitumor activity by inducing autophagy and apoptosis in lung cancer |
| - | vitro+vivo, | Lung, | A549 | - | vitro+vivo, | Lung, | H1299 |
| 6276- | DL, | Tam, | Combination of tamoxifen and D-limonene enhances therapeutic efficacy in breast cancer cells |
| - | in-vitro, | BC, | MCF7 |
| 6328- | DRE, | Hydroalcoholic extract of Taraxacum officinale induces apoptosis and autophagy in 4T1 breast cancer cells |
| - | in-vitro, | BC, | 4T1 |
| 6343- | DRE, | Dandelion root extract affects ESCC progression via regulating multiple signal pathways |
| - | vitro+vivo, | ESCC, | NA |
| 6318- | DRE, | Dandelion root extract affects colorectal cancer proliferation and survival through the activation of multiple death signalling pathways |
| - | vitro+vivo, | CRC, | HCT116 | - | NA, | Nor, | NCM460 |
| 6327- | DRE, | Effect of Methanolic Extract of Dandelion Roots on Cancer Cell Lines and AMP-Activated Protein Kinase Pathway |
| - | in-vitro, | Liver, | HepG2 | - | in-vitro, | BC, | MCF7 | - | in-vitro, | CRC, | HCT116 | - | in-vitro, | Nor, | Hs27 |
| 6360- | DRE, | Dandelion Seed Extract Affects Tumor Progression and Enhances the Sensitivity of Cisplatin in Esophageal Squamous Cell Carcinoma |
| - | in-vitro, | ESCC, | KYSE450 | - | in-vitro, | ESCC, | Eca109 |
| 6743- | DSF, | Disulfiram/Copper Activates ER Stress to Promote Immunogenic Cell Death of Oral Squamous Cell Carcinoma |
| - | in-vitro, | OS, | NA |
| 6742- | DSF, | Localized Sustained Release of Copper Enhances Anti-Tumor Effects of Disulfiram in Head and Neck Cancer |
| - | in-vitro, | HNSCC, | NA |
| 5010- | DSF, | Cu, | Rad, | Disulfiram/Copper Combined with Irradiation Induces Immunogenic Cell Death in Melanoma |
| - | in-vivo, | Melanoma, | B16-F10 |
| - | vitro+vivo, | Melanoma, | NA | - | Case Report, | Melanoma, | NA |
| 1613- | EA, | Ellagitannins in Cancer Chemoprevention and Therapy |
| - | Review, | Var, | NA |
| 6801- | EA, | A radiotherapeutic paradox: ellagic acid sensitizes tumors while attenuating radiation-induced myocardial injury |
| - | vitro+vivo, | BC, | 4T1 |
| 27- | EA, | Ellagic acid inhibits human pancreatic cancer growth in Balb c nude mice |
| - | in-vivo, | PC, | PANC1 |
| 6634- | Ech, | Echinacea purpurea: Pharmacology, phytochemistry and analysis methods |
| - | Review, | Var, | NA |
| 7237- | EGb 761, | Ginkgo biloba Extract Mechanism Inhibits Hepatocellular Carcinoma through the Nuclear Factor-κB/p53 Signaling Pathway |
| - | in-vitro, | HCC, | HepG2 |
| 7220- | EGb 761, | Ginkgo Biloba Extract Inhibits Metastasis and ERK/Nuclear Factor kappa B (NF-κB) Signaling Pathway in Gastric Cancer |
| - | vitro+vivo, | GC, | SGC-7901 |
Query results interpretion may depend on "conditions" listed in the research papers. Such Conditions may include : -low or high Dose -format for product, such as nano of lipid formations -different cell line effects -synergies with other products -if effect was for normal or cancerous cells
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