TumCG Cancer Research Results

TumCG, Tumor cell growth: Click to Expand ⟱
Source:
Type:
Normal cells grow and divide in a regulated manner through the cell cycle, which consists of phases (G1, S, G2, and M).
Cancer cells often bypass these regulatory mechanisms, leading to uncontrolled proliferation. This can result from mutations in genes that control the cell cycle, such as oncogenes (which promote cell division) and tumor suppressor genes (which inhibit cell division).
Scientific Papers found: Click to Expand⟱
813- GAR,  GEM,    Dietary Garcinol Arrests Pancreatic Cancer in p53 and K-ras Conditional Mutant Mouse Model
- in-vivo, PC, NA
TumCG↓, OS↑,
819- GAR,    Enhanced Hsa-miR-181d/p-STAT3 and Hsa-miR-181d/p-STAT5A Ratios Mediate the Anticancer Effect of Garcinol in STAT3/5A-Addicted Glioblastoma
- in-vivo, GBM, U87MG - in-vitro, GBM, GBM
OCT4↓, SOX2↓, TumCG↓,
822- GAR,    Garcinol, a Polyisoprenylated Benzophenone Modulates Multiple Proinflammatory Signaling Cascades Leading to the Suppression of Growth and Survival of Head and Neck Carcinoma
- vitro+vivo, HNSCC, NA
ROS↑, STAT3↓, cSrc↓, JAK1↓, JAK2↓, NF-kB↓, TGF-β↓, TumCG↓,
825- GAR,    Garcinol-induced apoptosis in prostate and pancreatic cancer cells is mediated by NF- kappaB signaling
- in-vitro, Pca, LNCaP - in-vitro, Pca, Bxpc-3 - in-vitro, Pca, PC3 - in-vitro, Pca, C4-2B
TumCG↓, Apoptosis↑, NF-kB↓,
793- GAR,    Garcinol inhibits tumour cell proliferation, angiogenesis, cell cycle progression and induces apoptosis via NF-κB inhibition in oral cancer
- in-vitro, SCC, SCC9 - in-vitro, SCC, SCC4 - in-vitro, SCC, SCC25
TumCG↓, Apoptosis↑, TumCCA↑, NF-kB↓, COX2↓, VEGF↓,
28- GEN,    Genistein decreases the breast cancer stem-like cell population through Hedgehog pathway
- in-vivo, BC, MCF-7
HH↓, Smo↓, Gli1↓, TumCG↓, TumCP↓, Apoptosis↑, CSCs↓,
29- GEN,    Genistein inhibits the stemness properties of prostate cancer cells through targeting Hedgehog-Gli1 pathway
- in-vivo, Pca, 22Rv1 - in-vivo, Pca, DU145
HH↓, Gli1↓, CSCs↓, TumCI↓, EMT↓, TumCG↓, CD44↓,
1116- GI,    6-Shogaol Inhibits the Cell Migration of Colon Cancer by Suppressing the EMT Process Through the IKKβ/NF-κB/Snail Pathway
- in-vitro, Colon, Caco-2 - in-vitro, CRC, HCT116
TumCG↓, Apoptosis↑, TumCMig↓, MMP2↓, N-cadherin↓, IKKα↓, p‑NF-kB↓, Snail↓, VEGF↓,
32- GlaB,    Gli1/DNA interaction is a druggable target for Hedgehog-dependent tumors
- in-vivo, MB, NA
HH↓, Gli1↓, PTCH1↓, TumCG↓, CSCs↓,
843- Gra,    Graviola (Annona muricata) Exerts Anti-Proliferative, Anti-Clonogenic and Pro-Apoptotic Effects in Human Non-Melanoma Skin Cancer UW-BCC1 and A431 Cells In Vitro: Involvement of Hedgehog Signaling
- in-vitro, NMSC, A431 - in-vitro, NMSC, UW-BCC1 - in-vitro, Nor, NHEKn
TumCG↓, TumCCA↑, Cyc↓, Apoptosis↑, cl‑Casp3↑, cl‑Casp8↑, cl‑PARP↑, HH↓, Smo↓, Gli1↓, GLI2↓, Shh↓, Sufu↑, BAX↑, Bcl-2↓, *toxicity↓,
841- Gra,    The Chemopotential Effect of Annona muricata Leaves against Azoxymethane-Induced Colonic Aberrant Crypt Foci in Rats and the Apoptotic Effect of Acetogenin Annomuricin E in HT-29 Cells: A Bioassay-Guided Approach
- in-vitro, CRC, HT-29 - in-vitro, Nor, CCD841
PCNA↓, Bcl-2↓, BAX↑, *MDA↓, lipid-P↓, TumCG↓, MMP↓, Cyt‑c↑, Casp3↑, Casp7↑, Casp9↑, *ROS↓, LDH↓, *toxicity↓, selectivity↑,
855- Gra,    Antiproliferative activity of ionic liquid-graviola fruit extract against human breast cancer (MCF-7) cell lines using flow cytometry techniques
- in-vitro, BC, MCF-7
TumCG↓, TumCP↓, TumCCA↑, Apoptosis↑,
1292- GSE,  EGCG,    Antiproliferative and Apoptotic Effects Triggered by Grape Seed Extract (GSE) versus Epigallocatechin and Procyanidins on Colon Cancer Cell Lines
- in-vitro, Colon, Caco-2 - in-vitro, CRC, HCT8
TumCG↓, Apoptosis↑,
2511- H2,    Molecular hydrogen suppresses glioblastoma growth via inducing the glioma stem-like cell differentiation
- in-vivo, GBM, U87MG
TumCG↓, OS↑, CD133↓, Ki-67↓, angioG↓, Diff↑, TumCMig↓, TumCI↓, Dose↝, BBB↑, mt-ROS↑,
2516- H2,    Hydrogen Gas in Cancer Treatment
- Review, Var, NA
*Half-Life↓, *ROS↓, *selectivity↑, *SOD↑, *HO-1↑, *NRF2↑, *chemoP↑, *radioP↑, ROS↑, *Inflam↓, eff↑, *TNF-α↓, *IL6↓, *cl‑Casp8↑, *Bax:Bcl2↓, *Apoptosis↓, *cardioP↑, *hepatoP↑, *RenoP↑, *chemoP↑, eff↝, chemoP↑, radioP↑, eff↑, TumCG↓, Ki-67↓, VEGF↓, selectivity↑,
3770- H2,    Role of Molecular Hydrogen in Ageing and Ageing-Related Diseases
- Review, AD, NA - Review, Park, NA
*antiOx↑, *NRF2↑, *HO-1↑, *Inflam↓, *neuroP↑, *cardioP↑, *other↓, *ROS↓, *NADPH↓, *Catalase↑, *GPx1↑, *NO↓, *mt-ROS↓, *SIRT3↑, *SIRT1↑, *TLR4↓, *mTOR↓, *cognitive↑, *Sepsis↓, *PTEN↓, *Akt↓, *NLRP3↓, *AntiAg↑, *IL6↓, *TNF-α↓, *IL1β↓, *MDA↓, *memory↑, *FOXO3↑, TumCG↓, *LDL↓,
292- HCA,    Hydroxycitric Acid Inhibits Chronic Myelogenous Leukemia Growth through Activation of AMPK and mTOR Pathway
- in-vitro, AML, K562
ACLY↓, AMPK↑, mTOR↑, eIF2α↑, ATFs↑, TumCG↓,
293- HCA,  Tam,    Hydroxycitric acid potentiates the cytotoxic effect of tamoxifen in MCF-7 breast cancer cells through inhibition of ATP citrate lyase
- in-vitro, BC, MCF-7
TumCG↓, Apoptosis↑, ACLY↓, ACC-α↓, Fas↓,
1625- HCA,    In S. cerevisiae hydroxycitric acid antagonizes chronological aging and apoptosis regardless of citrate lyase
- Review, Nor, NA
CRM↑, ACLY↓, TumAuto↑, Inflam↓, TumCG↓, toxicity∅, lipoGen↓, *ROS↓, *OCR↓,
2400- HCAs,    The Mixture of Ferulic Acid and P-Coumaric Acid Suppresses Colorectal Cancer through lncRNA 495810/PKM2 Mediated Aerobic Glycolysis
- in-vitro, CRC, NA - in-vivo, CRC, NA
PKM2↓, Glycolysis↓, TumCG↓,
2407- HCAs,    2'-hydroxycinnamaldehyde inhibits cancer cell proliferation and tumor growth by targeting the pyruvate kinase M2
- in-vitro, Pca, DU145 - in-vitro, Pca, LNCaP
p‑PKM2↓, TumCG↓,
1153- HNK,    Honokiol Eliminates Glioma/Glioblastoma Stem Cell-Like Cells via JAK-STAT3 Signaling and Inhibits Tumor Progression by Targeting Epidermal Growth Factor Receptor
- in-vitro, GBM, U251 - in-vitro, GBM, U87MG - in-vivo, NA, NA
tumCV↓, Apoptosis↑, TumCMig↓, TumCI↓, Bcl-2↓, EGFR↓, CD133↓, Nestin↓, Akt↓, ERK↓, Casp3↑, p‑STAT3↓, TumCG↓,
1021- HNK,    Honokiol suppress the PD-L1 expression to improve anti-tumor immunity in lung cancer
- in-vivo, Lung, NA
PD-L1↓, T-Cell↑, CD4+↑, CD8+↑, TumCG↓,
1120- HNK,    Honokiol suppresses renal cancer cells' metastasis via dual-blocking epithelial-mesenchymal transition and cancer stem cell properties through modulating miR-141/ZEB2 signaling
- vitro+vivo, RCC, NA
EMT↓, CSCs↓, TumCG↓, miR-141↑,
4523- HNK,  MAG,  BA,    Honokiol-Magnolol-Baicalin Possesses Synergistic Anticancer Potential and Enhances the Efficacy of Anti-PD-1 Immunotherapy in Colorectal Cancer by Triggering GSDME-Dependent Pyroptosis
- in-vitro, CRC, HCT116 - in-vitro, CRC, LoVo - in-vivo, CRC, HCT116
AntiCan↑, eff↑, TumCP↓, TumCCA↓, cycD1/CCND1↓, Pyro↑, Apoptosis↑, cl‑GSDME↑, Bcl-2↓, Cyt‑c↑, Casp9↑, TumCG↓,
4688- HNK,    Honokiol Suppresses Renal Cancer Cells’ Metastasis via Dual-Blocking Epithelial-Mesenchymal Transition and Cancer Stem Cell Properties through Modulating miR-141/ZEB2 Signaling
- vitro+vivo, RCC, A498
CSCs↓, EMT↓, TumCG↓, PI3K↓, Akt↓, mTOR↓, p‑Akt↓, PTEN↑, Wnt↓, β-catenin/ZEB1↓,
4642- HT,    Hydroxytyrosol, a natural molecule from olive oil, suppresses the growth of human hepatocellular carcinoma cells via inactivating AKT and nuclear factor-kappa B pathways
- in-vitro, HCC, HepG2 - NA, NA, Hep3B - NA, NA, SK-HEP-1
TumCP↓, TumCCA↑, Apoptosis↑, Akt↓, NF-kB↓, TumCG↓, angioG↓,
601- HT,    Dihydroxyphenylethanol induces apoptosis by activating serine/threonine protein phosphatase PP2A and promotes the endoplasmic reticulum stress response in human colon carcinoma cells
- in-vivo, NA, HT-29
TumCG↓, Apoptosis↑, ER Stress↑, UPR↑, CHOP↑, JNK↑, TNF-α↓, PPP2R1A↑,
1293- Ins,    Inositol Hexaphosphate Inhibits Growth and Induces G1 Arrest and Apoptotic Death of Androgen-Dependent Human Prostate Carcinoma LNCaP Cells
- vitro+vivo, Pca, LNCaP
TumCG↓, TumCCA↑, P21↑, CDK4↓, cycD1/CCND1↓, RB1↑, E2Fs↓,
2178- itraC,    Itraconazole inhibits tumor growth via CEBPB-mediated glycolysis in colorectal cancer
- in-vivo, CRC, HCT116
TumCG↓, Glycolysis↓, CEBPB?, ENO1↓, LDHA↓, PKM2↓, GAPDH↓, ECAR↓, OCR↓,
1070- IVM,    Ivermectin accelerates autophagic death of glioma cells by inhibiting glycolysis through blocking GLUT4 mediated JAK/STAT signaling pathway activation
- vitro+vivo, GBM, NA
TumCG↓, LC3II↑, p62↓, ATP↓, Pyruv↓, GlucoseCon↑, HK2↓, PFK1↓, GLUT4↓, Glycolysis↓, JAK2↓, p‑STAT3↓, p‑STAT5↓,
1918- JG,    ROS -mediated p53 activation by juglone enhances apoptosis and autophagy in vivo and in vitro
- in-vitro, Liver, HepG2 - in-vivo, NA, NA
TumCG↓, TumCP↓, Apoptosis↑, TumAuto↑, AMPK↑, mTOR↑, P53↑, H2O2↑, ROS↑, toxicity↝, p62↓, DR5↑, Casp8↑, PARP↑, cl‑Casp3↑,
1926- JG,    Mechanism of juglone-induced apoptosis of MCF-7 cells by the mitochondrial pathway
- in-vitro, BC, MCF-7
TumCG↓, ROS↑, MMP↓, i-Ca+2↑, BAX↑, Bcl-2↓, Cyt‑c↑, Casp3?,
1921- JG,    Juglone induces ferroptotic effect on hepatocellular carcinoma and pan-cancer via the FOSL1-HMOX1 axis
- in-vitro, PC, NA - vitro+vivo, PC, NA
TumCG↓, Ferroptosis↑, ROS↑, Iron↑, lipid-P↑, MDA↑, GSH↓, FOSL1↑, HO-1↑,
5099- JG,    Juglone induces ferroptosis in glioblastoma cells by inhibiting the Nrf2-GPX4 axis through the phosphorylation of p38MAPK
- vitro+vivo, GBM, LN229 - vitro+vivo, GBM, T98G
Ferroptosis↑, p‑MAPK↑, NRF2↓, GPx4↓, TumPF↓, Apoptosis↑, ROS↑, GSH↓, lipid-P↑, Ki-67↓, TumCG↓,
5117- JG,    https://pubmed.ncbi.nlm.nih.gov/31283929/
- vitro+vivo, Liver, NA
TumCG↓, TumCP↓, Apoptosis↑, TumAuto↑, AMPK↑, mTOR↑, P53↑, H2O2↑, ROS↑,
863- Lae,    Amygdalin inhibits the growth of renal cell carcinoma cells in vitro
- in-vitro, RCC, NA
TumCG↓, TumCP↓, TumCCA↑, CDK1↓, CycB/CCNB1↓, E-cadherin↝, N-cadherin↝,
1788- LE,    Activation of rapid signaling pathways and the subsequent transcriptional regulation for the proliferation of breast cancer MCF-7 cells by the treatment with an extract of Glycyrrhiza glabra root
- in-vitro, BC, MCF-7
TumCG↑,
1025- LT,  Api,    Luteolin and its derivative apigenin suppress the inducible PD-L1 expression to improve anti-tumor immunity in KRAS-mutant lung cancer
- in-vivo, Lung, NA
TumCG↓, Apoptosis↑, PD-L1↓, p‑STAT3↓,
1317- LT,    Luteolin Suppresses Teratoma Cell Growth and Induces Cell Apoptosis via Inhibiting Bcl-2
- vitro+vivo, Ovarian, PA1
Bcl-2↓, BAX↑, Apoptosis↑, TumCG↓,
2903- LT,    Luteolin induces apoptosis by ROS/ER stress and mitochondrial dysfunction in gliomablastoma
- in-vitro, GBM, U251 - in-vitro, GBM, U87MG - in-vivo, NA, NA
ER Stress↑, ROS↑, PERK↑, eIF2α↑, ATF4↑, CHOP↑, Casp12↑, eff↓, UPR↑, MMP↓, Cyt‑c↑, Bcl-2↓, BAX↑, TumCG↓, Weight∅, ALAT∅, AST∅,
2918- LT,    Luteolin inhibits melanoma growth in vitro and in vivo via regulating ECM and oncogenic pathways but not ROS
- in-vitro, Melanoma, A375 - in-vivo, Melanoma, NA - in-vitro, Melanoma, SK-MEL-28
TumCG↓, ROS↑, ECM/TCF↓,
4778- Lyco,    Lycopene exerts cytotoxic effects by mitochondrial reactive oxygen species–induced apoptosis in glioblastoma multiforme
- in-vitro, GBM, GBM8401
BBB↑, Apoptosis↑, TumCP↑, P53↑, CycB/CCNB1↓, cycD1/CCND1↓, TumCCA↓, mt-ROS↑, TumCG↓,
4783- Lyco,    Lycopene suppresses gastric cancer cell growth without affecting normal gastric epithelial cells
- in-vitro, GC, AGS - in-vitro, GC, SGC-7901 - in-vitro, Nor, GES-1
TumCG↓, TumCCA↑, Apoptosis↑, MMP↓, selectivity↑, cycE1↓, TP53↑, *antiOx↑,
4799- Lyco,    Anticancer Properties of Lycopene
- Review, Var, NA
Risk↓, TumCG↓, *antiOx↑, *Inflam↓, TumCP↓, TumCCA↑,
4796- Lyco,    The Anti-proliferation Effects of Lycopene on Breast Cancer Cells
- in-vitro, BC, MCF-7 - in-vitro, Nor, MCF10
TumCG↓, selectivity↑, *BioAv↑, *antiOx↑, *ROS↓, Risk↓, *cardioP↑,
4795- Lyco,    Updates on the Anticancer Profile of Lycopene and its Probable Mechanism against Breast and Gynecological Cancer
- Review, BC, NA
TumCG↓, TumCCA↑, Apoptosis↑, P53↝, BAX↝, cycD1/CCND1↓, ERK↓, Akt↓, STAT3↓, NRF2↝, NF-kB↓, ITGB1↓, ITGA5↓, FAK↓, MMP9↓, EMT↓,
4794- Lyco,    Anticancer Effect of Lycopene in Gastric Carcinogenesis
- Review, GC, NA
*AntiCan↑, *ROS↓, *GSH↑, *GPx↑, *GSTs↑, TumCG↓, Apoptosis↑, ERK↓, Bcl-2↓, BAX↑, Cyt‑c↑, TumCCA↑, *DNAdam↓,
2545- M-Blu,    Reversing the Warburg Effect as a Treatment for Glioblastoma
- in-vitro, GBM, U87MG - NA, AD, NA - in-vitro, GBM, A172 - in-vitro, GBM, T98G
Warburg↓, OCR↑, lactateProd↓, TumCP↓, TumCCA↑, AMPK↑, ACC↓, Cyc↓, neuroP↑, Cyt‑c↝, Glycolysis↓, ECAR↓, TumCG↓, other↓,
2541- M-Blu,    Spectroscopic Study of Methylene Blue Interaction with Coenzymes and its Effect on Tumor Metabolism
- in-vivo, Var, NA
TumCG↓, Glycolysis↓, OXPHOS↑, ROS↑, OCR↑, GlucoseCon↑, lactateProd↓,

Showing Research Papers: 301 to 350 of 598
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* indicates research on normal cells as opposed to diseased cells
Total Research Paper Matches: 598

Pathway results for Effect on Cancer / Diseased Cells:


Redox & Oxidative Stress ⓘ

Ferroptosis↑, 2,   GPx4↓, 1,   GSH↓, 2,   H2O2↑, 2,   HO-1↑, 1,   Iron↑, 1,   lipid-P↓, 1,   lipid-P↑, 2,   MDA↑, 1,   NRF2↓, 1,   NRF2↝, 1,   OXPHOS↑, 1,   ROS↑, 10,   mt-ROS↑, 2,  

Mitochondria & Bioenergetics ⓘ

ATP↓, 1,   MMP↓, 4,   OCR↓, 1,   OCR↑, 2,  

Core Metabolism/Glycolysis ⓘ

ACC↓, 1,   ACC-α↓, 1,   ACLY↓, 3,   ALAT∅, 1,   AMPK↑, 4,   CRM↑, 1,   ECAR↓, 2,   ENO1↓, 1,   GAPDH↓, 1,   GlucoseCon↑, 2,   Glycolysis↓, 5,   HK2↓, 1,   lactateProd↓, 2,   LDH↓, 1,   LDHA↓, 1,   lipoGen↓, 1,   PFK1↓, 1,   PKM2↓, 2,   p‑PKM2↓, 1,   Pyruv↓, 1,   Warburg↓, 1,  

Cell Death ⓘ

Akt↓, 4,   p‑Akt↓, 1,   Apoptosis↑, 21,   BAX↑, 6,   BAX↝, 1,   Bcl-2↓, 8,   Casp12↑, 1,   Casp3?, 1,   Casp3↑, 2,   cl‑Casp3↑, 2,   Casp7↑, 1,   Casp8↑, 1,   cl‑Casp8↑, 1,   Casp9↑, 2,   Cyt‑c↑, 5,   Cyt‑c↝, 1,   DR5↑, 1,   Fas↓, 1,   Ferroptosis↑, 2,   cl‑GSDME↑, 1,   JNK↑, 1,   p‑MAPK↑, 1,   PPP2R1A↑, 1,   Pyro↑, 1,  

Kinase & Signal Transduction ⓘ

cSrc↓, 1,  

Transcription & Epigenetics ⓘ

other↓, 1,   tumCV↓, 1,  

Protein Folding & ER Stress ⓘ

ATFs↑, 1,   CHOP↑, 2,   eIF2α↑, 2,   ER Stress↑, 2,   PERK↑, 1,   UPR↑, 2,  

Autophagy & Lysosomes ⓘ

LC3II↑, 1,   p62↓, 2,   TumAuto↑, 3,  

DNA Damage & Repair ⓘ

P53↑, 3,   P53↝, 1,   PARP↑, 1,   cl‑PARP↑, 1,   PCNA↓, 1,   TP53↑, 1,  

Cell Cycle & Senescence ⓘ

CDK1↓, 1,   CDK4↓, 1,   Cyc↓, 2,   CycB/CCNB1↓, 2,   cycD1/CCND1↓, 4,   cycE1↓, 1,   E2Fs↓, 1,   P21↑, 1,   RB1↑, 1,   TumCCA↓, 2,   TumCCA↑, 11,  

Proliferation, Differentiation & Cell State ⓘ

CD133↓, 2,   CD44↓, 1,   CEBPB?, 1,   CSCs↓, 5,   Diff↑, 1,   EMT↓, 4,   ERK↓, 3,   FOSL1↑, 1,   Gli1↓, 4,   HH↓, 4,   mTOR↓, 1,   mTOR↑, 3,   Nestin↓, 1,   OCT4↓, 1,   PI3K↓, 1,   PTCH1↓, 1,   PTEN↑, 1,   Shh↓, 1,   Smo↓, 2,   SOX2↓, 1,   STAT3↓, 2,   p‑STAT3↓, 3,   p‑STAT5↓, 1,   Sufu↑, 1,   TumCG↓, 49,   TumCG↑, 1,   Wnt↓, 1,  

Migration ⓘ

i-Ca+2↑, 1,   E-cadherin↝, 1,   FAK↓, 1,   GLI2↓, 1,   ITGA5↓, 1,   ITGB1↓, 1,   Ki-67↓, 3,   miR-141↑, 1,   MMP2↓, 1,   MMP9↓, 1,   N-cadherin↓, 1,   N-cadherin↝, 1,   Snail↓, 1,   TGF-β↓, 1,   TumCI↓, 3,   TumCMig↓, 3,   TumCP↓, 9,   TumCP↑, 1,   TumPF↓, 1,   β-catenin/ZEB1↓, 1,  

Angiogenesis & Vasculature ⓘ

angioG↓, 2,   ATF4↑, 1,   ECM/TCF↓, 1,   EGFR↓, 1,   VEGF↓, 3,  

Barriers & Transport ⓘ

BBB↑, 2,   GLUT4↓, 1,  

Immune & Inflammatory Signaling ⓘ

CD4+↑, 1,   COX2↓, 1,   IKKα↓, 1,   Inflam↓, 1,   JAK1↓, 1,   JAK2↓, 2,   NF-kB↓, 5,   p‑NF-kB↓, 1,   PD-L1↓, 2,   T-Cell↑, 1,   TNF-α↓, 1,  

Drug Metabolism & Resistance ⓘ

Dose↝, 1,   eff↓, 1,   eff↑, 3,   eff↝, 1,   selectivity↑, 4,  

Clinical Biomarkers ⓘ

ALAT∅, 1,   AST∅, 1,   EGFR↓, 1,   Ki-67↓, 3,   LDH↓, 1,   PD-L1↓, 2,   TP53↑, 1,  

Functional Outcomes ⓘ

AntiCan↑, 1,   chemoP↑, 1,   neuroP↑, 1,   OS↑, 2,   radioP↑, 1,   Risk↓, 2,   toxicity↝, 1,   toxicity∅, 1,   Weight∅, 1,  

Infection & Microbiome ⓘ

CD8+↑, 1,  
Total Targets: 179

Pathway results for Effect on Normal Cells:


Redox & Oxidative Stress ⓘ

antiOx↑, 4,   Catalase↑, 1,   GPx↑, 1,   GPx1↑, 1,   GSH↑, 1,   GSTs↑, 1,   HO-1↑, 2,   MDA↓, 2,   NRF2↑, 2,   ROS↓, 6,   mt-ROS↓, 1,   SIRT3↑, 1,   SOD↑, 1,  

Mitochondria & Bioenergetics ⓘ

OCR↓, 1,  

Core Metabolism/Glycolysis ⓘ

LDL↓, 1,   NADPH↓, 1,   SIRT1↑, 1,  

Cell Death ⓘ

Akt↓, 1,   Apoptosis↓, 1,   Bax:Bcl2↓, 1,   cl‑Casp8↑, 1,  

Transcription & Epigenetics ⓘ

other↓, 1,  

DNA Damage & Repair ⓘ

DNAdam↓, 1,  

Proliferation, Differentiation & Cell State ⓘ

FOXO3↑, 1,   mTOR↓, 1,   PTEN↓, 1,  

Migration ⓘ

AntiAg↑, 1,  

Angiogenesis & Vasculature ⓘ

NO↓, 1,  

Immune & Inflammatory Signaling ⓘ

IL1β↓, 1,   IL6↓, 2,   Inflam↓, 3,   TLR4↓, 1,   TNF-α↓, 2,  

Protein Aggregation ⓘ

NLRP3↓, 1,  

Drug Metabolism & Resistance ⓘ

BioAv↑, 1,   Half-Life↓, 1,   selectivity↑, 1,  

Clinical Biomarkers ⓘ

IL6↓, 2,  

Functional Outcomes ⓘ

AntiCan↑, 1,   cardioP↑, 3,   chemoP↑, 2,   cognitive↑, 1,   hepatoP↑, 1,   memory↑, 1,   neuroP↑, 1,   radioP↑, 1,   RenoP↑, 1,   toxicity↓, 2,  

Infection & Microbiome ⓘ

Sepsis↓, 1,  
Total Targets: 49

Scientific Paper Hit Count for: TumCG, Tumor cell growth
26 Curcumin
25 Magnetic Fields
17 Phenethyl isothiocyanate
15 Quercetin
14 Berberine
13 Silver-NanoParticles
13 Chemotherapy
13 Sulforaphane (mainly Broccoli)
13 Shikonin
12 Vitamin C (Ascorbic Acid)
12 Magnetic Field Rotating
12 Bicarbonate(Sodium)
11 Alpha-Lipoic-Acid
11 Baicalein
11 EGCG (Epigallocatechin Gallate)
10 Capsaicin
10 Apigenin (mainly Parsley)
9 Silymarin (Milk Thistle) silibinin
9 Garcinol
8 Astragalus
8 Artemisinin
8 Resveratrol
8 Dichloroacetate
8 salinomycin
8 diet FMD Fasting Mimicking Diet
8 Phenylbutyrate
8 Pterostilbene
8 Urolithin
7 Allicin (mainly Garlic)
7 HydroxyCitric Acid
7 Ashwagandha(Withaferin A)
7 Boron
7 Boswellia (frankincense)
7 Gambogic Acid
6 Radiotherapy/Radiation
6 Metformin
6 Betulinic acid
6 immunotherapy
6 Coenzyme Q10
6 Deguelin
6 diet Methionine-Restricted Diet
6 Sulfasalazine
6 Magnolol
6 Lycopene
6 Magnesium
6 Rosmarinic acid
5 chitosan
5 Melatonin
5 Berbamine
5 Cisplatin
5 Chrysin
5 Gemcitabine (Gemzar)
5 Fisetin
5 Honokiol
5 Juglone
4 3-bromopyruvate
4 Astaxanthin
4 Atorvastatin
4 Brucea javanica
4 Butyrate
4 Caffeic Acid Phenethyl Ester (CAPE)
4 Citric Acid
4 Emodin
4 Luteolin
4 Piperine
4 Piperlongumine
4 Selenite (Sodium)
4 Thymoquinone
4 Vitamin K2
4 VitK3,menadione
3 Caffeic acid
3 doxorubicin
3 Paclitaxel
3 Baicalin
3 Bufalin/Huachansu
3 brusatol
3 Bruteridin(bergamot juice)
3 Carvacrol
3 Celastrol
3 Chlorogenic acid
3 Selenium NanoParticles
3 Photodynamic Therapy
3 Genistein (soy isoflavone)
3 Graviola
3 Hydrogen Gas
3 Niclosamide (Niclocide)
3 Propyl gallate
3 Plumbagin
3 Aflavin-3,3′-digallate
2 2-DeoxyGlucose
2 Auranofin
2 Fenbendazole
2 Andrographis
2 Ascorbyl Palmitate
2 Dipyridamole
2 Biochanin A
2 Bifidobacterium
2 Bromelain
2 Carnosic acid
2 Oxygen, Hyperbaric
2 diet Short Term Fasting
2 Disulfiram
2 Copper and Cu NanoParticles
2 Ellagic acid
2 Gallic acid
2 Galloflavin
2 tamoxifen
2 Hydroxycinnamic-acid
2 HydroxyTyrosol
2 Methylene blue
2 Oroxylin-A
2 Oleuropein
2 Orlistat
2 Psoralidin
2 Hyperthermia
2 Oxaliplatin
2 Spermidine
2 Ursolic acid
2 Whole Body Vibration
1 5-fluorouracil
1 Anzaroot, Astragalus fasciculifolius Bioss
1 octreotide
1 Diclofenac
1 Acetyl-l-carnitine
1 Anti-oxidants
1 5-Aminolevulinic acid
1 Aloe anthraquinones
1 beta-glucans
1 temozolomide
1 Bacopa monnieri
1 Caffeine
1 urea
1 Cat’s Claw
1 Cannabidiol
1 Celecoxib
1 Chocolate
1 Cinnamon
1 Calorie Restriction Mimetics
1 Bicalutamide
1 Dichloroacetophenone(2,2-)
1 Bortezomib
1 Docosahexaenoic Acid
1 diet Ketogenic
1 diet Plant based
1 Zinc
1 Evodiamine
1 PXD, phenoxodiol
1 Sorafenib (brand name Nexavar)
1 Electrical Pulses
1 erastin
1 Fucoidan
1 Shilajit/Fulvic Acid
1 Ginger/6-Shogaol/Gingerol
1 Glabrescione B
1 Grapeseed extract
1 Inositol
1 itraconazole
1 Ivermectin
1 Laetrile B17 Amygdalin
1 Licorice
1 mebendazole
1 metronomic chemo
1 Methylglyoxal
1 Mushroom Chaga
1 Naringin
1 Nimbolide
1 Noscapine
1 Parthenolide
1 raloxifen
1 Salvia officinalis
1 Vorinostat
1 Selenium
1 irinotecan
1 Salvia miltiorrhiza
1 Saikosaponin B1 and D
1 Sutherlandioside D
1 Taurine
1 Tomatine
1 Tumor Treating Fields
1 Vitamin B1/Thiamine
1 Vitamin B5,Pantothenic Acid
1 Transarterial Chemoembolization
1 γ-Tocotrienol
Query results interpretion may depend on "conditions" listed in the research papers.
Such Conditions may include : 
  -low or high Dose
  -format for product, such as nano of lipid formations
  -different cell line effects
  -synergies with other products 
  -if effect was for normal or cancerous cells

Filter Conditions: Pro/AntiFlg:%  IllCat:%  CanType:%  Cells:%  prod#:%  Target#:323  State#:%  Dir#:%
  wNotes=0  sortOrder:rid,rpid

 

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