| 1324- | EMD, | Is Emodin with Anticancer Effects Completely Innocent? Two Sides of the Coin |
| - | Review, | Var, | NA |
| 1325- | EMD, | PacT, | Emodin enhances antitumor effect of paclitaxel on human non-small-cell lung cancer cells in vitro and in vivo |
| - | vitro+vivo, | Lung, | A549 |
| 1321- | EMD, | Antitumor effects of emodin on LS1034 human colon cancer cells in vitro and in vivo: roles of apoptotic cell death and LS1034 tumor xenografts model |
| - | in-vitro, | CRC, | LS1034 | - | in-vivo, | NA, | NA |
| 1320- | EMD, | SRF, | Emodin Sensitizes Hepatocellular Carcinoma Cells to the Anti-Cancer Effect of Sorafenib through Suppression of Cholesterol Metabolism |
| - | vitro+vivo, | HCC, | HepG2 | - | in-vitro, | HCC, | Hep3B | - | in-vitro, | HCC, | HUH7 | - | vitro+vivo, | Hepat, | SK-HEP-1 |
| 1319- | EMD, | Emodin treatment of papillary thyroid cancer cell lines in vitro inhibits proliferation and enhances apoptosis via downregulation of NF‑κB and its upstream TLR4 signaling |
| - | in-vitro, | Thyroid, | TPC-1 | - | in-vitro, | Thyroid, | IHH4 |
| 1318- | EMD, | Aloe-emodin Induces Apoptosis in Human Liver HL-7702 Cells through Fas Death Pathway and the Mitochondrial Pathway by Generating Reactive Oxygen Species |
| - | in-vitro, | Nor, | HL7702 |
| 1326- | EMD, | Emodin induces a reactive oxygen species-dependent and ATM-p53-Bax mediated cytotoxicity in lung cancer cells |
| - | in-vitro, | Lung, | A549 |
| 1328- | EMD, | Emodin induces apoptosis of human tongue squamous cancer SCC-4 cells through reactive oxygen species and mitochondria-dependent pathways |
| - | in-vitro, | Tong, | SCC4 |
| 1329- | EMD, | Aloe-emodin induces cell death through S-phase arrest and caspase-dependent pathways in human tongue squamous cancer SCC-4 cells |
| - | in-vitro, | Tong, | SCC4 |
| 1331- | EMD, | Aloe-emodin induces apoptosis of human nasopharyngeal carcinoma cells via caspase-8-mediated activation of the mitochondrial death pathway |
| - | in-vitro, | NPC, | NA |
| 1296- | EMD, | Emodin inhibits LOVO colorectal cancer cell proliferation via the regulation of the Bcl-2/Bax ratio and cytochrome c |
| - | in-vitro, | CRC, | LoVo |
| 1330- | EMD, | Aloe emodin-induced apoptosis in t-HSC/Cl-6 cells involves a mitochondria-mediated pathway |
| - | in-vitro, | NA, | NA |
| 1247- | EMD, | Emodin exerts antitumor effects in ovarian cancer cell lines by preventing the development of cancer stem cells via epithelial mesenchymal transition |
| - | vitro+vivo, | Ovarian, | SKOV3 | - | in-vitro, | Ovarian, | A2780S |
| 1245- | EMD, | Emodin Exhibits Strong Cytotoxic Effect in Cervical Cancer Cells by Activating Intrinsic Pathway of Apoptosis |
| - | in-vitro, | Cerv, | HeLa |
| 1246- | EMD, | Emodin reduces Breast Cancer Lung Metastasis by suppressing Macrophage-induced Breast Cancer Cell Epithelial-mesenchymal transition and Cancer Stem Cell formation |
| - | in-vivo, | BC, | NA |
| 7045- | EMD, | TSG, | Synergic effects and possible mechanism of emodin and stilbene glycosides on colorectal cancer |
| - | vitro+vivo, | CRC, | NA |
| 6825- | EMD, | Advances in the pharmacological effects and molecular mechanisms of emodin in the treatment of metabolic diseases |
| - | Review, | Nor, | NA |
| 6824- | EMD, | Neuroprotective, Anti-Inflammatory and Antifibrillogenic Offerings by Emodin against Alzheimer’s Dementia: A Systematic Review |
| - | Review, | AD, | NA |
| 6814- | EMD, | Emodin: A Review of its Pharmacology, Toxicity and Pharmacokinetics |
| - | Review, | Nor, | NA |
| 6815- | EMD, | NMR-based Metabolomic Techniques Identify the Toxicity of Emodin in HepG2 Cells |
| - | in-vitro, | Liver, | HepG2 |
| 6816- | EMD, | Emodin attenuates Alzheimer's disease by activating the protein kinase C signaling pathway |
| - | in-vivo, | AD, | NA |
| 6817- | EMD, | Emodin inhibits aggregation of amyloid-β peptide 1–42 and improves cognitive deficits in Alzheimer's disease transgenic mice |
| - | in-vivo, | AD, | NA |
| 6818- | EMD, | Emodin Rescued Hyperhomocysteinemia-Induced Dementia and Alzheimer's Disease-Like Features in Rats |
| - | in-vivo, | AD, | NA |
| 6819- | EMD, | Recent advances in the therapeutic potential of emodin for human health |
| - | Review, | Nor, | NA |
| 6820- | EMD, | The Health Benefits of Emodin, a Natural Anthraquinone Derived from Rhubarb—A Summary Update |
| - | Review, | Nor, | NA | - | Review, | Arthritis, | NA | - | Review, | AD, | NA |
| 6821- | EMD, | Emodin derivatives as promising multi-aspect intervention agents for amyloid aggregation: molecular docking/dynamics simulation, bioactivities evaluation, and cytoprotection |
| - | Study, | AD, | NA |
| 6822- | EMD, | Behavioral, Histopathological, and Biochemical Implications of Aloe Emodin in Copper-Aβ-Induced Alzheimer's Disease-like Model Rats |
| - | in-vivo, | AD, | NA |
| 6823- | EMD, | Role of emodin to prevent gastrointestinal cancers: recent trends and future prospective |
| - | Review, | Var, | NA |
| 6826- | EMD, | Exploring the therapeutic potential of natural compounds for Alzheimer's disease: Mechanisms of action and pharmacological properties |
| 6827- | EMD, | Mechanism of Emodin in the Treatment of Rheumatoid Arthritis |
| - | Review, | Arthritis, | NA |
| 6828- | EMD, | Neuroprotective effect of emodin against Alzheimer's disease via Nrf2 signaling in U251 cells and APP/PS1 mice |
| - | in-vitro, | AD, | U251 |
| 6829- | EMD, | Molecular Mechanisms of Action of Emodin: As an Anti-Cardiovascular Disease Drug |
| 6830- | EMD, | Anticancer activity of emodin is associated with downregulation of CD155 |
| - | vitro+vivo, | Melanoma, | B16-BL6 | - | in-vitro, | BC, | E0771 | - | in-vitro, | BC, | 4T1 |
| 6831- | EMD, | PI, | Effect of piperine on the bioavailability and pharmacokinetics of emodin in rats |
| - | in-vivo, | Nor, | NA |
| 6832- | EMD, | Emodin induces apoptosis of human cervical cancer hela cells via intrinsic mitochondrial and extrinsic death receptor pathway |
| - | in-vitro, | Cerv, | HeLa |
| 6833- | EMD, | Anticancer potential of emodin |
| - | Review, | Var, | NA |
| 6834- | EMD, | Emodin induces apoptosis of human cervical cancer cells through poly(ADP-ribose) polymerase cleavage and activation of caspase-9 |
| - | in-vitro, | Cerv, | HeLa |
| 6835- | EMD, | Suppressed transformation and induced differentiation of HER-2/neu-overexpressing breast cancer cells by emodin |
| - | in-vitro, | BC, | NA |
| 6836- | EMD, | Emodin and the Anthraquinone Scaffold: Therapeutic Promise and Strategies to Overcome Translational Barriers |
| - | Review, | Nor, | NA |
| 3830- | EMD, | Traditional Chinese Medicine: Role in Reducing β-Amyloid, Apoptosis, Autophagy, Neuroinflammation, Oxidative Stress, and Mitochondrial Dysfunction of Alzheimer’s Disease |
| - | Review, | AD, | NA |
| 950- | EMD, | Emodin Decreases Hepatic Hypoxia-Inducible Factor-1[Formula: see text] by Inhibiting its Biosynthesis |
| - | in-vivo, | NA, | NA | - | in-vitro, | Liver, | HepG2 |
| 988- | EMD, | Emodin Induced Necroptosis and Inhibited Glycolysis in the Renal Cancer Cells by Enhancing ROS |
| - | in-vitro, | RCC, | NA |
| 5228- | EMD, | Evaluating anticancer activity of emodin by enhancing antioxidant activities and affecting PKC/ADAMTS4 pathway in thioacetamide-induced hepatocellular carcinoma in rats |
| - | in-vivo, | HCC, | NA |
| 5227- | EMD, | Emodin and emodin-rich rhubarb inhibits histone deacetylase (HDAC) activity and cardiac myocyte hypertrophy |
| - | vitro+vivo, | Nor, | NA |
| 5226- | EMD, | Emodin and rhein decrease levels of hypoxia-inducible factor-1α in human pancreatic cancer cells and attenuate cancer cachexia in athymic mice carrying these cells |
| - | vitro+vivo, | Pca, | MIA PaCa-2 |
| 5225- | EMD, | Emodin inhibits growth and induces apoptosis in an orthotopic hepatocellular carcinoma model by blocking activation of STAT3 |
| - | vitro+vivo, | HCC, | HepG2 | - | in-vitro, | HCC, | Hep3B | - | in-vitro, | HCC, | HUH7 |
| 5224- | EMD, | Emodin Isolated from Polygoni cuspidati Radix Inhibits TNF-α and IL-6 Release by Blockading NF-κB and MAP Kinase Pathways in Mast Cells Stimulated with PMA Plus A23187 |
| 5223- | EMD, | Emodin inhibits colon cancer by altering BCL-2 family proteins and cell survival pathways |
| - | in-vitro, | CRC, | DLD1 | - | in-vitro, | Nor, | CCD841 |
| 2422- | EMD, | Anti-Cancer Effects of Emodin on HepG2 Cells as Revealed by 1H NMR Based Metabolic Profiling |
| - | in-vitro, | HCC, | HepG2 |
| 2345- | EMD, | Emodin ameliorates antioxidant capacity and exerts neuroprotective effect via PKM2-mediated Nrf2 transactivation |
| - | in-vitro, | AD, | PC12 |
Query results interpretion may depend on "conditions" listed in the research papers. Such Conditions may include : -low or high Dose -format for product, such as nano of lipid formations -different cell line effects -synergies with other products -if effect was for normal or cancerous cells
Filter Conditions: Pro/AntiFlg:% IllCat:% CanType:% Cells:% prod#:% Target#:% State#:% Dir#:%
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