| 6580- | EU, | Eurycomanone Blocks TGF-β1-Induced Epithelial-to-Mesenchymal Transition, Migration, and Invasion Pathways in Human Non-Small Cell Lung Cancer Cells by Targeting Smad and Non-Smad Signaling |
| - | in-vitro, | Lung, | A549 | - | in-vitro, | Lung, | Calu-1 |
| 6581- | EU, | Bioavailability of Eurycomanone in Its Pure Form and in a Standardised Eurycoma longifolia Water Extract |
| - | in-vitro, | Colon, | Caco-2 | - | in-vivo, | Nor, | NA |
| 6582- | EU, | Eurycoma longifolia (Jack) Improves Serum Total Testosterone in Men: A Systematic Review and Meta-Analysis of Clinical Trials |
| - | Review, | Nor, | NA |
| 6583- | EU, | Inactivation of AKT/NF-κB signaling by eurycomalactone decreases human NSCLC cell viability and improves the chemosensitivity to cisplatin |
| - | in-vitro, | NSCLC, | A549 | - | in-vitro, | NSCLC, | Calu-1 |
| 6584- | EU, | Eurycoma longifolia: an overview on the pharmacological properties for the treatment of common cancer |
| - | Review, | Var, | NA |
| 6585- | EU, | Anti-Tumor Activity of Eurycoma longifolia Root Extracts against K-562 Cell Line: In Vitro and In Vivo Study |
| - | vitro+vivo, | AML, | K562 |
| 6586- | EU, | Unfermented Freeze-Dried Leaf Extract of Tongkat Ali (Eurycoma longifolia Jack.) Induced Cytotoxicity and Apoptosis in MDA-MB-231 and MCF-7 Breast Cancer Cell Lines |
| 6772- | Eug, | Antimicrobial activity of eugenol and essential oils containing eugenol: A mechanistic viewpoint |
| - | Review, | Nor, | NA |
| 6384- | Eug, | Eugenol modulates the NOD1-NF-κB signaling pathway via targeting NF-κB protein in triple-negative breast cancer cells |
| - | in-vitro, | BC, | MDA-MB-231 | - | in-vitro, | BC, | MDA-MB-453 |
| 6355- | Eug, | Pharmacological and Toxicological Properties of Eugenol |
| - | Review, | Var, | NA |
| 6356- | Eug, | Cin, | Investigating the Molecular Mechanisms of the Anticancer Effects of Eugenol and Cinnamaldehyde Against Colorectal Cancer (CRC) Cells In Vitro |
| - | in-vitro, | CRC, | SW-620 | - | in-vitro, | CRC, | Caco-2 | - | in-vitro, | Nor, | NCM460 |
| 6383- | Eug, | In Vitro Incorporation of Radioiodinated Eugenol on Adenocarcinoma Cell Lines (Caco2, MCF7, and PC3) |
| - | in-vitro, | Colon, | Caco-2 | - | in-vitro, | BC, | MCF7 | - | in-vitro, | Pca, | PC3 |
| 6390- | Eug, | Molecular mechanisms of eugenol as an antitumour bioactive compound: A comprehensive review |
| - | Review, | Var, | NA |
| 6391- | Eug, | BCP, | 5-FU, | Exploring Mechanism of Actions for Eugenol and Beta-Caryophyllene to Combat Colorectal Cancer Chemotherapy Using Network Pharmacology |
| - | in-vitro, | CRC, | HCT116 |
| 6382- | Eug, | Eugenol enhances the chemotherapeutic potential of gemcitabine and induces anticarcinogenic and anti-inflammatory activity in human cervical cancer cells |
| - | in-vitro, | Cerv, | NA |
| 6381- | Eug, | Biological Properties and Prospects for the Application of Eugenol—A Review |
| - | Review, | Var, | NA |
| 6380- | Eug, | Bioactivity of Eugenol: A Potential Antibiotic Adjuvant with Minimal Ecotoxicological Impact |
| - | in-vitro, | Nor, | NA |
| 6379- | Eug, | Safety assessment of a standardized polyphenolic extract of clove buds: Subchronic toxicity and mutagenicity studies |
| - | in-vivo, | Nor, | NA |
| 6378- | Eug, | Effects of Eugenol on the Central Nervous System: Its Possible Application to Treatment of Alzheimer's Disease, Depression, and Parkinson's Disease |
| - | Review, | AD, | NA |
| 6377- | Eug, | Pharmacological Properties and Health Benefits of Eugenol: A Comprehensive Review |
| - | Review, | Var, | NA | - | Review, | AD, | NA |
| 6376- | Eug, | Preparation, characterization, oral bioavailability, and pharmacodynamic study of eugenol-porous silica solidified powder |
| - | NA, | Nor, | NA |
| 6389- | Eug, | Molecular Insights into the Management of Eugenol's Anticancer Action Against Colon Cancer: A Detailed Review |
| - | Review, | Colon, | NA |
| 6385- | Eug, | Anticancer potential of eugenol in hepatocellular carcinoma through modulation of oxidative stress, inflammation, apoptosis, and proliferation mechanisms |
| - | in-vivo, | HCC, | HepG2 |
| 6386- | Eug, | A comprehensive and systematic review on potential anticancer activities of eugenol: From pre-clinical evidence to molecular mechanisms of action |
| - | Review, | Var, | NA |
| 6387- | Eug, | Anticancer and antibacterial effects of a clove bud essential oil-based nanoscale emulsion system |
| - | in-vitro, | Thyroid, | NA | - | in-vitro, | Nor, | HEK293 |
| 6388- | Eug, | Eugenol’s anti-cancer properties, its modulation of signalling pathways, and cascades across various cancers: A review |
| - | Review, | Var, | NA |
| 6335- | Eug, | Eugenol with antioxidant activity inhibits MMP-9 related to metastasis in human fibrosarcoma cells |
| - | in-vitro, | Nor, | NA |
| 6336- | Eug, | Eugenol induces apoptosis and inhibits invasion and angiogenesis in a rat model of gastric carcinogenesis induced by MNNG |
| - | in-vivo, | GC, | NA |
| 6337- | Eug, | Eugenol alleviated breast precancerous lesions through HER2/PI3K-AKT pathway-induced cell apoptosis and S-phase arrest |
| - | in-vitro, | BC, | MCF-10AT |
| 6338- | Eug, | Tumor suppressive roles of eugenol in human lung cancer cells |
| - | in-vitro, | Lung, | A549 |
| 6339- | Eug, | Induction of apoptosis by eugenol in human breast cancer cells |
| - | in-vitro, | BC, | NA |
| 6340- | Eug, | Eugenol triggers apoptosis in breast cancer cells through E2F1/survivin down-regulation |
| - | in-vitro, | BC, | MCF7 | - | in-vitro, | BC, | T47D | - | in-vitro, | BC, | MDA-MB-231 |
| 6341- | Eug, | A Metabolomic Investigation of Eugenol on Colorectal Cancer Cell Line HT-29 by Modifying the Expression of APC, p53, and KRAS Genes |
| - | NA, | Colon, | HT29 |
| 6325- | Eug, | Anticancer Properties of Eugenol: A Review |
| - | Review, | Var, | NA |
| 6324- | Eug, | Pharmacodynamic, pharmacokinetic, toxicity, and recent advances in Eugenol's potential benefits against natural and chemical noxious agents: A mechanistic review |
| - | Review, | Var, | NA |
| 6323- | Eug, | Eugenol: An Insight Into the Anticancer Perspective and Pharmacological Aspects |
| - | Review, | Var, | NA | - | Review, | Arthritis, | NA |
| 6333- | Eug, | Cisplatin, | Rad, | Eugenol Exerts Apoptotic Effect and Modulates the Sensitivity of HeLa Cells to Cisplatin and Radiation |
| - | in-vitro, | Cerv, | HeLa |
| 6332- | Eug, | Anti-metastatic and anti-proliferative activity of eugenol against triple negative and HER2 positive breast cancer cells |
| - | in-vitro, | BC, | MDA-MB-231 | - | in-vitro, | BC, | SkBr3 |
| 6331- | Eug, | Eugenol-Induced Autophagy and Apoptosis in Breast Cancer Cells via PI3K/AKT/FOXO3a Pathway Inhibition |
| - | in-vitro, | BC, | MDA-MB-231 |
| 6330- | Eug, | Molecular Mechanisms of Action of Eugenol in Cancer: Recent Trends and Advancement |
| - | Review, | Var, | NA |
| 6847- | EVO, | Evodiamine as an anticancer agent: a comprehensive review on its therapeutic application, pharmacokinetic, toxicity, and metabolism in various cancers |
| - | Review, | Var, | NA |
| 6846- | EVO, | Evodiamine Inhibits Colorectal Cancer Growth via RTKs Mediated PI3K/AKT/p53 Signaling Pathway |
| - | in-vitro, | CRC, | HT29 | - | in-vitro, | CRC, | HCT116 |
| 6845- | EVO, | Evodiamine, a Novel NOTCH3 Methylation Stimulator, Significantly Suppresses Lung Carcinogenesis in Vitro and in Vivo |
| - | vitro+vivo, | NSCLC, | A549 | - | in-vitro, | Lung, | H1299 |
| 6844- | EVO, | Evodiamine inhibits both stem cell and non-stem-cell populations in human cancer cells by targeting heat shock protein 70 |
| - | vitro+vivo, | Lung, | A549 | - | in-vitro, | Colon, | HCT116 | - | in-vitro, | BC, | MDA-MB-231 | - | in-vitro, | Nor, | MCF10 |
| 6843- | EVO, | Effects of evodiamine on PI3K/Akt and MAPK/ERK signaling pathways in pancreatic cancer cells |
| - | in-vivo, | PC, | PANC1 | - | in-vitro, | PC, | SW1990 |
| 6842- | EVO, | Evodiamine activates cellular apoptosis through suppressing PI3K/AKT and activating MAPK in glioma |
| - | in-vitro, | GBM, | U251 | - | in-vitro, | GBM, | LN229 |
| 6841- | EVO, | Evodiamine induces reactive oxygen species-dependent apoptosis and necroptosis in human melanoma A-375 cells |
| - | in-vitro, | Melanoma, | A375 |
| 6840- | EVO, | Evodiamine Induces G2/M Arrest and Apoptosis via Mitochondrial and Endoplasmic Reticulum Pathways in H446 and H1688 Human Small-Cell Lung Cancer Cells |
| - | in-vitro, | Lung, | H446 | - | in-vitro, | Lung, | H1688 |
| 6839- | EVO, | Activation of JNK Contributes to Evodiamine-Induced Apoptosis and G2/M Arrest in Human Colorectal Carcinoma Cells: A Structure-Activity Study of Evodiamine |
| - | in-vitro, | CRC, | COLO205 | - | in-vitro, | Colon, | HT29 |
| 6837- | EVO, | Evodiamine Stabilizes Topoisomerase I-DNA Cleavable Complex to Inhibit Topoisomerase I Activity |
| - | in-vitro, | BC, | MCF7 |
Query results interpretion may depend on "conditions" listed in the research papers. Such Conditions may include : -low or high Dose -format for product, such as nano of lipid formations -different cell line effects -synergies with other products -if effect was for normal or cancerous cells
Filter Conditions: Pro/AntiFlg:% IllCat:% CanType:% Cells:% prod#:% Target#:% State#:% Dir#:%
wNotes=0 sortOrder:rid,rpid