antiOx Cancer Research Results

antiOx, anti-oxidant activities: Click to Expand ⟱
Source:
Type:
Various antioxidants such as Nrf2, SODs, catalase, GPxs, PRDXs, and GSTs are altered in different cancers and have been linked to prognosis. Their overexpression can correlate with aggressive tumor behavior and resistance to treatment in many contexts.
Scientific Papers found: Click to Expand⟱
2861- FIS,    The neuroprotective effects of fisetin, a natural flavonoid in neurodegenerative diseases: Focus on the role of oxidative stress
- Review, Nor, NA - Review, Stroke, NA - Review, Park, NA
*antiOx↑, *ROS↓, *neuroP↑, *NO↑, BioAv↝, *BBB↑, *toxicity↑, *eff↑, *GSH↑, *SOD↑, *Aβ↓, *12LOX↓, *COX2↓, *Catalase↑, *Inflam↓, *TNF-α↓, *IL6↑, *lipid-P↓, NF-kB↓, IL1β↓, NRF2↑, HO-1↑, GSTs↑, cognitive↑, *BDNF↑,
2845- FIS,    Fisetin: A bioactive phytochemical with potential for cancer prevention and pharmacotherapy
- Review, Var, NA
PI3K↓, Akt↓, mTOR↓, p38↓, *antiOx↑, *neuroP↑, Casp3↑, Bcl-2↓, Mcl-1↓, BAX↑, BIM↑, BAD↑, AMPK↑, ACC↑, DNAdam↑, MMP↓, eff↑, ROS↑, cl‑PARP↑, Cyt‑c↑, Diablo↑, P53↑, p65↓, Myc↓, HSP70/HSPA5↓, HSP27↓, COX2↓, Wnt↓, EGFR↓, NF-kB↓, TumCCA↑, CDK2↓, CDK4↓, cycD1/CCND1↓, cycA1/CCNA1↓, P21↑, MMP2↓, MMP9↓, TumMeta↓, MMP1↓, MMP3↓, MMP7↓, MET↓, N-cadherin↓, Vim↓, Snail↓, Fibronectin↓, E-cadherin↑, uPA↓, ChemoSen↑, EMT↓, Twist↓, Zeb1↓, cFos↓, cJun↓, EGF↓, angioG↓, VEGF↓, eNOS↓, *NRF2↑, HO-1↑, NRF2↓, GSTs↓, ATF4↓,
2824- FIS,    Fisetin in Cancer: Attributes, Developmental Aspects, and Nanotherapeutics
- Review, Var, NA
*antiOx↑, *Inflam↓, angioG↓, BioAv↓, BioAv↑, TumCP↓, TumCI↓, TumCMig↓, *neuroP↑, EMT↓, ROS↑, selectivity↑, EGFR↓, NF-kB↓, VEGF↓, MMP9↓, MMP↓, cl‑PARP↑, Casp7↑, Casp8↑, Casp9↑, *ROS↓, uPA↓, MMP1↓, Wnt↓, Akt↓, PI3K↓, ERK↓, Half-Life↝,
2825- FIS,    Exploring the molecular targets of dietary flavonoid fisetin in cancer
- Review, Var, NA
*Inflam↓, *antiOx↓, *ERK↑, *p‑cMyc↑, *NRF2↑, *GSH↑, *HO-1↑, mTOR↓, PI3K↓, Akt↓, TumCCA↑, cycD1/CCND1↓, cycE/CCNE↓, CDK2↓, CDK4↓, CDK6↓, P21↑, p27↑, JNK↑, MMP2↓, MMP9↓, uPA↓, NF-kB↓, cFos↓, cJun↓, E-cadherin↑, Vim↓, N-cadherin↓, EMT↓, MMP↓, Cyt‑c↑, Diablo↑, Casp↑, cl‑PARP↑, P53↑, COX2↓, PGE2↓, HSP70/HSPA5↓, HSP27↓, DNAdam↑, Casp3↑, Casp9↑, ROS↑, AMPK↑, NO↑, Ca+2↑, mTORC1↓, p70S6↓, ROS↓, ER Stress↑, IRE1↑, ATF4↑, GRP78/BiP↑, eff↑, eff↑, eff↑, RadioS↑, ChemoSen↑, Half-Life↝,
2827- FIS,    The Potential Role of Fisetin, a Flavonoid in Cancer Prevention and Treatment
- Review, Var, NA
*antiOx↑, *Inflam↓, neuroP↑, hepatoP↑, RenoP↑, cycD1/CCND1↓, TumCCA↑, MMPs↓, VEGF↓, MAPK↓, NF-kB↓, angioG↓, Beclin-1↑, LC3s↑, ATG5↑, Bcl-2↓, BAX↑, Casp↑, TNF-α↓, Half-Life↓, MMP↓, mt-ROS↑, cl‑PARP↑, CDK2↓, CDK4↓, Cyt‑c↑, Diablo↑, DR5↑, Fas↑, PCNA↓, Ki-67↓, p‑H3↓, chemoP↑, Ca+2↑, Dose↝, CDC25↓, CDC2↓, CHK1↑, Chk2↑, ATM↑, PCK1↓, RAS↓, p‑p38↓, Rho↓, uPA↓, MMP7↓, MMP13↓, GSK‐3β↑, E-cadherin↑, survivin↓, VEGFR2↓, IAP2↓, STAT3↓, JAK1↓, mTORC1↓, mTORC2↓, NRF2↑,
2828- FIS,    Fisetin, a Potent Anticancer Flavonol Exhibiting Cytotoxic Activity against Neoplastic Malignant Cells and Cancerous Conditions: A Scoping, Comprehensive Review
- Review, Var, NA
*neuroP↑, *antiOx↑, *Inflam↓, RenoP↑, COX2↓, Wnt↓, EGFR↓, NF-kB↓, Casp3↑, Ca+2↑, Casp8↑, TumCCA↑, CDK1↓, PI3K↓, Akt↓, mTOR↓, MAPK↓, *P53↓, *P21↓, *p16↓, mTORC1↓, mTORC2↓, P53↑, P21↑, cycD1/CCND1↓, cycA1/CCNA1↓, CDK2↓, CDK4↓, BAX↑, Bcl-2↓, PCNA↓, HER2/EBBR2↓, Cyt‑c↑, MMP↓, cl‑Casp9↑, MMP2↓, MMP9↓, cl‑PARP↑, uPA↓, DR4↑, DR5↑, ROS↓, AIF↑, CDC25↓, Dose↑, CHOP↑, ROS↑, cMyc↓, cardioP↑,
2831- FIS,    Fisetin as a chemoprotective and chemotherapeutic agent: mechanistic insights and future directions in cancer therapy
- Review, Var, NA
TumCG↓, ER Stress↑, antiOx↓, ROS↓, ChemoSen↑,
5392- FIS,  AsP,    Fisetin topical delivery via ascorbyl palmitate/hyaluronan-enhanced limosomes: a novel paradigm for preventing UVB-induced skin photoaging
- in-vivo, Nor, NA
eff↑, *antiOx↑, *MMP9↓, *TNF-α↓, *NF-kB↓, *SOD↑, *Catalase↑, *AntiAge↑, *Inflam↓, *JNK↓,
2313- Flav,    Flavonoids against the Warburg phenotype—concepts of predictive, preventive and personalised medicine to cut the Gordian knot of cancer cell metabolism
- Review, Var, NA
Warburg↓, antiOx↑, angioG↓, Glycolysis↓, PKM2↓, PKM2:PKM1↓, β-catenin/ZEB1↓, cMyc↓, HK2↓, Akt↓, mTOR↓, GLUT1↓, Hif1a↓,
4024- FulvicA,    ANTI-CARCINOGENIC ACTIVITY OF SHILAJIT REGARDING TO APOPTOSIS ASSAY IN CANCER CELLS: A SYSTEMATIC REVIEW OF IN-VITRO STUDIES
- Review, Var, NA
*Inflam↓, *antiOx↑, TumCG↓, tumCV↓, ROS↑, ChemoSen↑, toxicity↝,
4025- FulvicA,    Mumio (Shilajit) as a potential chemotherapeutic for the urinary bladder cancer treatment
- in-vitro, Bladder, T24/HTB-9 - Review, AD, NA
tumCV↓, selectivity↑, TumCCA↑, other↝, *neuroP↑, *memory↑, *tau↓, *other↝, *lipid-P↓, *VitC↑, *antiOx↑,
4026- FulvicA,    Shilajitin Cancer Treatment: Probable Mode of Action
- Review, Var, NA
*Inflam↓, *antiOx↑, Dose↝,
4016- FulvicA,    Shilajit: A Natural Phytocomplex with Potential Procognitive Activity
- Review, AD, NA
*tau↓, *AntiAge↑, *Strength↑, *Dose↝, *BioAv↑, *antiOx↑, *memory↑, *Inflam↓, *cognitive↑, *neuroP↑, *toxicity↝, *toxicity↑,
1773- GA,    Impact of Gallic Acid on Gut Health: Focus on the Gut Microbiome, Immune Response, and Mechanisms of Action
- Review, Var, NA
antiOx↑, AntiCan↑, Inflam↑, GutMicro↑, BioAv↝, BioAv↓, BioAv↑, TumMeta↓,
1189- Gb,    New insight into the mechanisms of Ginkgo biloba leaves in the treatment of cancer
- Review, NA, NA
Apoptosis↑, TumCP↓, TumCI↓, TumCMig↓, Inflam↓, antiOx↑, angioG↓,
3723- Gb,    Can We Use Ginkgo biloba Extract to Treat Alzheimer’s Disease? Lessons from Preclinical and Clinical Studies
- Review, AD, NA
*memory↑, *antiOx↑, *Casp3↓, *APP↓, *AChE↓, *Aβ↓, *5HT↑, *SOD↓, *MDA↓, *NO↓, *GSH↑, *Bcl-2↑, *BAX↑, *TNF-α↓, *IL1β↑, *iNOS↓, *IL10↓, *p‑tau↓, *ROS↓, *MAOB↓, *cognitive↑, *neuroP↑, *Apoptosis↓,
3721- Gb,    Ginkgo biloba Extract in Alzheimer’s Disease: From Action Mechanisms to Medical Practice
- Review, AD, NA
*antiOx↑, *ROS↓, *SOD↑, *Catalase↑, *GSR↑, *MMP↑, *Inflam↓, *Aβ↓, *memory↑, *Dose↝, *BBB↑, *neuroP↑,
6561- Ger,    Geraniol Pharmacokinetics, Bioavailability and Its Multiple Effects on the Liver Antioxidant and Xenobiotic-Metabolizing Enzymes
- in-vivo, Nor, NA
*Inflam↓, *antiOx↑, *neuroP↑, *AntiCan↑, *BioAv↝, *Dose↝, *toxicity↓, *Catalase↑, *NADPH↑, *GSR↑, *ALAT∅, *AST∅,
6562- Ger,    Potential Effects of Geraniol on Cancer and Inflammation-Related Diseases: A Review of the Recent Research Findings
- Review, Var, NA - Review, AD, NA
*Inflam↓, *AntiCan↑, *AntiBio↑, *antiOx↑, *neuroP↑, ROS↓, Apoptosis↑, TumCCA↑, P53↝, STAT3↓, Casp↝, *Catalase↑, *GSTs↑, *GPx↑, *AChE↓, *GSH↑, *SOD↑, *TBARS↓, *NO↓, *XO↓, *memory↑, *IL1β↓, *iNOS↓, *NF-kB↓, *COX2↓, *NRF2↑, *HO-1↑, *survivin↓, TumCP↓, TumCMig↓, TumCG↑, selectivity↑, TumMeta↓, angioG↓, Hif1a↓, Beclin-1↓,
6567- Ger,    Geraniin inhibits proliferation and induces apoptosis through inhibition of phosphatidylinositol 3-kinase/Akt pathway in human colorectal cancer in vitro and in vivo
- vitro+vivo, CRC, SW480 - in-vitro, CRC, HT29
AntiTum↑, *Inflam↓, *antiOx↓, TumCP↓, BAX↑, Casp3↑, Casp9↑, Bcl-2↓, TumCMig↓, TumCI↓, MMP2↓, MMP9↓, p‑PI3K↓, p‑Akt↓, Dose↝, TumCG↓,
6571- Ger,    Unlocking the therapeutic potential of Geraniol: an alternative perspective for metabolic disease management
- Review, Obesity, NA
*lipidLev↓, *antiOx↓, Inflam↓, *ROS↓, *BioAv↑, *AntiDiabetic↑, *Obesity↓,
4247- GI,    6-Shogaol from Dried Ginger Protects against Intestinal Ischemia/Reperfusion by Inhibiting Cell Apoptosis via the BDNF/TrkB/PI3K/AKT Pathway
- vitro+vivo, NA, NA
*BDNF↑, *TrkB↑, *PI3K↑, *Akt↑, *Apoptosis↓, *Inflam↓, *antiOx↑,
2464- GI,    The Effect of Ginger (Zingiber officinale) on Platelet Aggregation: A Systematic Literature Review
- Review, Nor, NA
*Inflam↓, *antiOx↑, *LDL↓, *AntiAg↑, *AntiAg∅,
2519- H2,    Hydrogen: an advanced and safest gas option for cancer treatment
- Review, Var, NA
antiOx↑, neuroP↓, BBB↑, toxicity∅, TumCP↓, Apoptosis↓, ROS↑, Hif1a↓, NF-kB↓, P53?, OS↑, chemoP↑,
2515- H2,    Recent Advances in Studies of Molecular Hydrogen against Sepsis
- Review, Sepsis, NA
*Sepsis↓, *Inflam↓, *antiOx↑, *ROS↓, *NADPH↓,
2513- H2,    Hydrogen therapy: from mechanism to cerebral diseases
- Review, Stroke, NA
*BBB?, *antiOx↑, *Inflam↓, *Apoptosis↓, *NF-kB↓, *Dose↝,
2510- H2,    Hydrogen acts as a therapeutic antioxidant by selectively reducing cytotoxic oxygen radicals
- in-vivo, Stroke, NA
*ROS↓, *antiOx↑,
2527- H2,    The healing effect of hydrogen-rich water on acute radiation-induced skin injury in rats
- in-vivo, Wounds, NA
*Dose↝, *SOD↑, *EGF↑, *antiOx↑, *Inflam↓, *Dose↝,
3770- H2,    Role of Molecular Hydrogen in Ageing and Ageing-Related Diseases
- Review, AD, NA - Review, Park, NA
*antiOx↑, *NRF2↑, *HO-1↑, *Inflam↓, *neuroP↑, *cardioP↑, *other↓, *ROS↓, *NADPH↓, *Catalase↑, *GPx1↑, *NO↓, *mt-ROS↓, *SIRT3↑, *SIRT1↑, *TLR4↓, *mTOR↓, *cognitive↑, *Sepsis↓, *PTEN↓, *Akt↓, *NLRP3↓, *AntiAg↑, *IL6↓, *TNF-α↓, *IL1β↓, *MDA↓, *memory↑, *FOXO3↑, TumCG↓, *LDL↓,
3771- H2,    Molecular Hydrogen Neuroprotection in Post-Ischemic Neurodegeneration in the Form of Alzheimer’s Disease Proteinopathy: Underlying Mechanisms and Potential for Clinical Implementation—Fantasy or Reality?
- Review, AD, NA - Review, Stroke, NA
*cognitive↑, AntiCan↑, *Inflam↓, *antiOx↑, *ROS↓, *neuroP↑, *SOD↑, *GPx↑, *MDA↑, *BBB↑, *OS↑, *Ca+2↓, *APP↓, *p‑tau↓,
3773- H2,    Role and mechanism of molecular hydrogen in the treatment of Parkinson’s diseases
- Review, Park, NA
*neuroP↑, *antiOx↑, *Inflam↓, *ROS↓, *NADPH↓, *NRF2↑, *BBB↑, *IL1β↓, *IL6↓, *TNF-α↓, *NF-kB↓, *NLRP3↓, *Sepsis↓, *p‑mTOR↓, *AMPK↑, *SIRT1↑, *HO-1↑,
3774- H2,    The role of hydrogen in Alzheimer’s disease
- Review, AD, NA
*Inflam↓, *antiOx↑, *NLRP3↓, *memory↑, *Aβ↓, *AMPK↑, *SIRT1↑, *FOXO3↑, *p‑p38↓, *JNK↓, *ROS↓, *cognitive↑, *ER(estro)↑, *BDNF↑,
3775- H2,    Molecular hydrogen therapy for neurological diseases: a review of current evidence
- Review, AD, NA - Review, Stroke, NA
*Inflam↓, *antiOx↑, *neuroP↑, *cognitive↑,
3776- H2,    The role of hydrogen in Alzheimer's disease
- Review, AD, NA
*antiOx↑, *Inflam↓, *NLRP3↓, *AMPK↑, *SIRT1↑, *FOXO3↑, *ROS↓, *BDNF↑,
3787- H2,    Hydrogen, a Novel Therapeutic Molecule, Regulates Oxidative Stress, Inflammation, and Apoptosis
- Review, AD, NA
*Inflam↓, *antiOx↑, *ROS↓, *other↝, *NF-kB↓, *IL2↓, *IL6↓, *TNF-α↓, *HO-1↑, Apoptosis↑, TumAuto↑, *Sepsis↓, *NLRP3↓, Pyro↑,
3765- H2,    Therapeutic Inhalation of Hydrogen Gas for Alzheimer’s Disease Patients and Subsequent Long-Term Follow-Up as a Disease-Modifying Treatment: An Open Label Pilot Study
- Study, AD, NA
*antiOx↑, *Inflam↓, *cognitive↑, *BBB↑,
3766- H2,    The role of hydrogen in Alzheimer′s disease
- Review, AD, NA
*antiOx↑, *Inflam↓, *AMPK↑, *SIRT1↑, *FOXO↑, *mtDam↓, *neuroP↑, *ROS↓, *p38↓, *cognitive↑, *BDNF↑, *memory↑, *lipid-P↓, *IL6↓, *TNF-α↓, *JNK↓, *NF-kB↓, *NLRP3↓,
3767- H2,    The role of hydrogen therapy in Alzheimer's disease management: Insights into mechanisms, administration routes, and future challenges
- Review, AD, NA
*Inflam↓, *neuroP↑, *toxicity↓, *antiOx↑, *ROS↓, *NLRP3↓, *IL1β↓, *mtDam↓, *ATP↑, *AMPK↑, *FOXO3↑, *SOD1↑, *Catalase↑, *NRF2↑, *NO↓, *MDA↓, *lipid-P↓, *memory↑, *ER(estro)↓, *BDNF↑, *cognitive↑, *APP↓, *BACE↓, *Aβ↓, *BP∅, *BBB↑,
4343- H2,    Inhibitory effects of hydrogen on in vitro platelet activation and in vivo prevention of thrombosis formation
- vitro+vivo, NA, NA
*antiOx↑, *AntiAg↑, *NO↑, *ERK↑,
4345- H2,    The Benefit of Hydrogen Gas as an Adjunctive Therapy for Chronic Obstructive Pulmonary Disease
- Human, NA, NA
*Inflam↓, *antiOx↑, *ROS↓, *NLRP3↑, *NF-kB↓, *SOD↑, *Catalase↑, *AntiAg↑,
4236- H2,    Neuroprotective effects of hydrogen inhalation in an experimental rat intracerebral hemorrhage model
- in-vivo, Stroke, NA
*neuroP↑, *Inflam↓, *antiOx↑, *BDNF↑, *Casp3↓,
3769- H2S,    Research progress of hydrogen sulfide in Alzheimer's disease from laboratory to hospital: a narrative review
- Review, AD, NA
*APP↓, *Apoptosis↓, *Inflam↓, *antiOx↑, *BP↓, *NLRP3↓, *ROS↓, *Aβ↓, *ER Stress↓,
1638- HCAs,    Anticancer potential of hydroxycinnamic acids: mechanisms, bioavailability, and therapeutic applications
- Review, Nor, NA
*BioAv↓, Inflam↓, COX2↓, TumCCA↑, ChemoSen↑, RadioS↑, selectivity↑, ROS↑, DNAdam↑, antiOx↑, SOD↑, Catalase↑, GPx↑, GSH↑, NRF2↑, NF-kB↓, Cyc↓, CDK1↑, P21↑, p27↑, P53↑, VEGF↓, MAPK↓,
1649- HCAs,    Anticancer Properties of Hydroxycinnamic Acids -A Review
- Review, Var, NA
*antiOx↑, MMP2↓, MMP9↓, VEGF↓, TGF-β↓, Bax:Bcl2↑, TumCCA↑, COX2↓, NF-kB↓,
2071- HNK,    Identification of senescence rejuvenation mechanism of Magnolia officinalis extract including honokiol as a core ingredient
- Review, Nor, HaCaT
*ROS↓, *antiOx↑, *AntiAge↑, *MMP↑, *ECAR↓, *Glycolysis↓, *PAR-2↓, *CXCL12↑, *BMAL1↑, *mt-ROS↓, *OXPHOS↓,
2082- HNK,    Revealing the role of honokiol in human glioma cells by RNA-seq analysis
- in-vitro, GBM, U87MG - in-vitro, GBM, U251
AntiCan↑, TumCP↑, TumAuto↑, Apoptosis↑, *BioAv↑, *neuroP↑, *NF-kB↑, MAPK↑, GPx4↑, Tf↑, BAX↑, Bcl-2↓, antiOx↑, Hif1a↓, Ferroptosis↑,
2873- HNK,    Honokiol Alleviates Oxidative Stress-Induced Neurotoxicity via Activation of Nrf2
- in-vitro, Nor, PC12
*neuroP↑, *GSH↑, *HO-1↑, *NADPH↑, *Trx1↑, *TrxR1↑, *NRF2↑, *ROS↓, *antiOx↑, *BBB↑, Dose↓,
2872- HNK,    Honokiol alleviated neurodegeneration by reducing oxidative stress and improving mitochondrial function in mutant SOD1 cellular and mouse models of amyotrophic lateral sclerosis
- in-vivo, ALS, NA - NA, Stroke, NA - NA, AD, NA - NA, Park, NA
*eff↑, *ROS↓, *GSH↑, *NRF2↑, *motorD↑, *OS↑, *neuroP↑, *BBB↑, *cognitive↑, *eff↑, *antiOx↑, *Cyt‑c↑, *PGC-1α↑,
2868- HNK,    Honokiol: A review of its pharmacological potential and therapeutic insights
- Review, Var, NA - Review, Sepsis, NA
*P-gp↓, *ROS↓, *TNF-α↓, *IL10↓, *IL6↓, eIF2α↑, CHOP↑, GRP78/BiP↑, BAX↑, cl‑Casp9↑, p‑PERK↑, ER Stress↑, Apoptosis↑, MMPs↓, cFLIP↓, CXCR4↓, Twist↓, HDAC↓, BMPs↑, p‑STAT3↓, mTOR↓, EGFR↓, NF-kB↓, Shh↓, VEGF↓, tumCV↓, TumCMig↓, TumCI↓, ERK↓, Akt↓, Bcl-2↓, Nestin↓, CD133↓, p‑cMET↑, RAS↑, chemoP↑, *NRF2↑, *NADPH↓, *p‑Rac1↓, *ROS↓, *IKKα↑, *NF-kB↓, *COX2↓, *PGE2↓, *Casp3↓, *hepatoP↑, *antiOx↑, *GSH↑, *Catalase↑, *RenoP↑, *ALP↓, *AST↓, *ALAT↓, *neuroP↑, *cardioP↑, *HO-1↑, *Inflam↓,
2867- HNK,    Honokiol ameliorates oxidative stress-induced DNA damage and apoptosis of c2c12 myoblasts by ROS generation and mitochondrial pathway
- in-vitro, Nor, C2C12
*antiOx↑, *ROS↓, *Bcl-2↑, *BAX↓, Casp9∅, Casp3∅, cl‑PARP∅, Cyt‑c?,

Showing Research Papers: 351 to 400 of 732
Prev Page 8 of 15 Next

* indicates research on normal cells as opposed to diseased cells
Total Research Paper Matches: 732

Pathway results for Effect on Cancer / Diseased Cells:


Redox & Oxidative Stress(tgid=1) ⓘ

antiOx↓, 1,   antiOx↑, 6,   Catalase↑, 1,   Ferroptosis↑, 1,   GPx↑, 1,   GPx4↑, 1,   GSH↑, 1,   GSTs↓, 1,   GSTs↑, 1,   HO-1↑, 2,   NRF2↓, 1,   NRF2↑, 3,   ROS↓, 4,   ROS↑, 7,   mt-ROS↑, 1,   SOD↑, 1,  

Metal & Cofactor Biology(tgid=2) ⓘ

Tf↑, 1,  

Mitochondria & Bioenergetics(tgid=3) ⓘ

AIF↑, 1,   CDC2↓, 1,   CDC25↓, 2,   EGF↓, 1,   MMP↓, 5,  

Core Metabolism/Glycolysis(tgid=4) ⓘ

ACC↑, 1,   AMPK↑, 2,   cMyc↓, 2,   Glycolysis↓, 1,   HK2↓, 1,   PCK1↓, 1,   PKM2↓, 1,   PKM2:PKM1↓, 1,   Warburg↓, 1,  

Cell Death(tgid=5) ⓘ

Akt↓, 6,   p‑Akt↓, 1,   Apoptosis↓, 1,   Apoptosis↑, 5,   BAD↑, 1,   BAX↑, 6,   Bax:Bcl2↑, 1,   Bcl-2↓, 6,   BIM↑, 1,   Casp↑, 2,   Casp↝, 1,   Casp3↑, 4,   Casp3∅, 1,   Casp7↑, 1,   Casp8↑, 2,   Casp9↑, 3,   Casp9∅, 1,   cl‑Casp9↑, 2,   cFLIP↓, 1,   Chk2↑, 1,   Cyt‑c↑, 4,   Cyt‑c?, 1,   Diablo↑, 3,   DR4↑, 1,   DR5↑, 2,   Fas↑, 1,   Ferroptosis↑, 1,   IAP2↓, 1,   JNK↑, 1,   MAPK↓, 3,   MAPK↑, 1,   Mcl-1↓, 1,   Myc↓, 1,   p27↑, 2,   p38↓, 1,   p‑p38↓, 1,   Pyro↑, 1,   survivin↓, 1,  

Kinase & Signal Transduction(tgid=6) ⓘ

HER2/EBBR2↓, 1,   p70S6↓, 1,  

Transcription & Epigenetics(tgid=7) ⓘ

cJun↓, 2,   p‑H3↓, 1,   other↝, 1,   tumCV↓, 3,  

Protein Folding & ER Stress(tgid=8) ⓘ

CHOP↑, 2,   eIF2α↑, 1,   ER Stress↑, 3,   GRP78/BiP↑, 2,   HSP27↓, 2,   HSP70/HSPA5↓, 2,   IRE1↑, 1,   p‑PERK↑, 1,  

Autophagy & Lysosomes(tgid=9) ⓘ

ATG5↑, 1,   Beclin-1↓, 1,   Beclin-1↑, 1,   LC3s↑, 1,   TumAuto↑, 2,  

DNA Damage & Repair(tgid=10) ⓘ

ATM↑, 1,   CHK1↑, 1,   DNAdam↑, 3,   P53?, 1,   P53↑, 4,   P53↝, 1,   cl‑PARP↑, 5,   cl‑PARP∅, 1,   PCNA↓, 2,  

Cell Cycle & Senescence(tgid=11) ⓘ

CDK1↓, 1,   CDK1↑, 1,   CDK2↓, 4,   CDK4↓, 4,   Cyc↓, 1,   cycA1/CCNA1↓, 2,   cycD1/CCND1↓, 4,   cycE/CCNE↓, 1,   P21↑, 4,   TumCCA↑, 8,  

Proliferation, Differentiation & Cell State(tgid=12) ⓘ

CD133↓, 1,   cFos↓, 2,   p‑cMET↑, 1,   EMT↓, 3,   ERK↓, 2,   GSK‐3β↑, 1,   HDAC↓, 1,   mTOR↓, 5,   mTORC1↓, 3,   mTORC2↓, 2,   Nestin↓, 1,   PI3K↓, 4,   p‑PI3K↓, 1,   RAS↓, 1,   RAS↑, 1,   Shh↓, 1,   STAT3↓, 2,   p‑STAT3↓, 1,   TumCG↓, 4,   TumCG↑, 1,   Wnt↓, 3,  

Migration(tgid=13) ⓘ

Ca+2↑, 3,   E-cadherin↑, 3,   Fibronectin↓, 1,   Ki-67↓, 1,   MET↓, 1,   MMP1↓, 2,   MMP13↓, 1,   MMP2↓, 5,   MMP3↓, 1,   MMP7↓, 2,   MMP9↓, 6,   MMPs↓, 2,   N-cadherin↓, 2,   Rho↓, 1,   Snail↓, 1,   TGF-β↓, 1,   TumCI↓, 4,   TumCMig↓, 5,   TumCP↓, 5,   TumCP↑, 1,   TumMeta↓, 3,   Twist↓, 2,   uPA↓, 5,   Vim↓, 2,   Zeb1↓, 1,   β-catenin/ZEB1↓, 1,  

Angiogenesis & Vasculature(tgid=14) ⓘ

angioG↓, 6,   ATF4↓, 1,   ATF4↑, 1,   EGFR↓, 4,   eNOS↓, 1,   Hif1a↓, 4,   NO↑, 1,   VEGF↓, 6,   VEGFR2↓, 1,  

Barriers & Transport(tgid=15) ⓘ

BBB↑, 1,   GLUT1↓, 1,  

Immune & Inflammatory Signaling(tgid=16) ⓘ

COX2↓, 5,   CXCR4↓, 1,   IL1β↓, 1,   Inflam↓, 3,   Inflam↑, 1,   JAK1↓, 1,   NF-kB↓, 10,   p65↓, 1,   PGE2↓, 1,   TNF-α↓, 1,  

Hormonal & Nuclear Receptors(tgid=20) ⓘ

CDK6↓, 1,  

Drug Metabolism & Resistance(tgid=21) ⓘ

BioAv↓, 2,   BioAv↑, 2,   BioAv↝, 2,   ChemoSen↑, 5,   Dose↓, 1,   Dose↑, 1,   Dose↝, 3,   eff↑, 5,   Half-Life↓, 1,   Half-Life↝, 2,   RadioS↑, 2,   selectivity↑, 4,  

Clinical Biomarkers(tgid=22) ⓘ

BMPs↑, 1,   EGFR↓, 4,   GutMicro↑, 1,   HER2/EBBR2↓, 1,   Ki-67↓, 1,   Myc↓, 1,  

Functional Outcomes(tgid=23) ⓘ

AntiCan↑, 3,   AntiTum↑, 1,   cardioP↑, 1,   chemoP↑, 3,   cognitive↑, 1,   hepatoP↑, 1,   neuroP↓, 1,   neuroP↑, 1,   OS↑, 1,   RenoP↑, 2,   toxicity↝, 1,   toxicity∅, 1,  
Total Targets: 206

Pathway results for Effect on Normal Cells:


NA, unassigned(tgid=0) ⓘ

AntiBio↑, 1,  

Redox & Oxidative Stress(tgid=1) ⓘ

antiOx↓, 3,   antiOx↑, 40,   Catalase↑, 9,   GPx↑, 2,   GPx1↑, 1,   GSH↑, 7,   GSR↑, 2,   GSTs↑, 1,   HO-1↑, 7,   lipid-P↓, 4,   MDA↓, 3,   MDA↑, 1,   NRF2↑, 9,   OXPHOS↓, 1,   ROS↓, 23,   mt-ROS↓, 2,   SIRT3↑, 1,   SOD↓, 1,   SOD↑, 7,   SOD1↑, 1,   TBARS↓, 1,   Trx1↑, 1,   TrxR1↑, 1,   VitC↑, 1,  

Mitochondria & Bioenergetics(tgid=3) ⓘ

ATP↑, 1,   EGF↑, 1,   MMP↑, 2,   mtDam↓, 2,   PGC-1α↑, 1,  

Core Metabolism/Glycolysis(tgid=4) ⓘ

12LOX↓, 1,   ALAT↓, 1,   ALAT∅, 1,   AMPK↑, 5,   BMAL1↑, 1,   p‑cMyc↑, 1,   ECAR↓, 1,   Glycolysis↓, 1,   LDL↓, 2,   lipidLev↓, 1,   NADPH↓, 4,   NADPH↑, 2,   SIRT1↑, 5,  

Cell Death(tgid=5) ⓘ

Akt↓, 1,   Akt↑, 1,   Apoptosis↓, 4,   BAX↓, 1,   BAX↑, 1,   Bcl-2↑, 2,   Casp3↓, 3,   Cyt‑c↑, 1,   iNOS↓, 2,   JNK↓, 3,   p38↓, 1,   p‑p38↓, 1,   survivin↓, 1,  

Transcription & Epigenetics(tgid=7) ⓘ

other↓, 1,   other↝, 2,  

Protein Folding & ER Stress(tgid=8) ⓘ

ER Stress↓, 1,  

DNA Damage & Repair(tgid=10) ⓘ

p16↓, 1,   P53↓, 1,  

Cell Cycle & Senescence(tgid=11) ⓘ

P21↓, 1,  

Proliferation, Differentiation & Cell State(tgid=12) ⓘ

ERK↑, 2,   FOXO↑, 1,   FOXO3↑, 4,   mTOR↓, 1,   p‑mTOR↓, 1,   PI3K↑, 1,   PTEN↓, 1,  

Migration(tgid=13) ⓘ

AntiAg↑, 4,   AntiAg∅, 1,   APP↓, 4,   Ca+2↓, 1,   CXCL12↑, 1,   MMP9↓, 1,   p‑Rac1↓, 1,  

Angiogenesis & Vasculature(tgid=14) ⓘ

NO↓, 4,   NO↑, 2,  

Barriers & Transport(tgid=15) ⓘ

BBB?, 1,   BBB↑, 8,   P-gp↓, 1,  

Immune & Inflammatory Signaling(tgid=16) ⓘ

COX2↓, 3,   IKKα↑, 1,   IL10↓, 2,   IL1β↓, 4,   IL1β↑, 1,   IL2↓, 1,   IL6↓, 5,   IL6↑, 1,   Inflam↓, 32,   NF-kB↓, 8,   NF-kB↑, 1,   PAR-2↓, 1,   PGE2↓, 1,   TLR4↓, 1,   TNF-α↓, 8,  

Synaptic & Neurotransmission(tgid=18) ⓘ

5HT↑, 1,   AChE↓, 2,   BDNF↑, 7,   tau↓, 2,   p‑tau↓, 2,   TrkB↑, 1,  

Protein Aggregation(tgid=19) ⓘ

Aβ↓, 6,   BACE↓, 1,   MAOB↓, 1,   NLRP3↓, 8,   NLRP3↑, 1,   XO↓, 1,  

Hormonal & Nuclear Receptors(tgid=20) ⓘ

ER(estro)↓, 1,   ER(estro)↑, 1,  

Drug Metabolism & Resistance(tgid=21) ⓘ

BioAv↓, 1,   BioAv↑, 3,   BioAv↝, 1,   Dose↝, 6,   eff↑, 3,  

Clinical Biomarkers(tgid=22) ⓘ

ALAT↓, 1,   ALAT∅, 1,   ALP↓, 1,   AST↓, 1,   AST∅, 1,   BP↓, 1,   BP∅, 1,   IL6↓, 5,   IL6↑, 1,  

Functional Outcomes(tgid=23) ⓘ

AntiAge↑, 3,   AntiCan↑, 2,   AntiDiabetic↑, 1,   cardioP↑, 2,   cognitive↑, 10,   hepatoP↑, 1,   memory↑, 9,   motorD↑, 1,   neuroP↑, 21,   Obesity↓, 1,   OS↑, 2,   RenoP↑, 1,   Strength↑, 1,   toxicity↓, 2,   toxicity↑, 2,   toxicity↝, 1,  

Infection & Microbiome(tgid=24) ⓘ

Sepsis↓, 4,  
Total Targets: 141

Scientific Paper Hit Count for: antiOx, anti-oxidant activities
37 Lycopene
31 Curcumin
28 Thymoquinone
25 Resveratrol
25 Alpha-Lipoic-Acid
24 Selenium NanoParticles
24 Quercetin
20 Silymarin (Milk Thistle) silibinin
18 Rosmarinic acid
18 Hydrogen Gas
16 Astaxanthin
16 Chlorogenic acid
14 Silver-NanoParticles
13 Berberine
13 Carvacrol
13 Eugenol
13 Ferulic acid
12 Baicalein
12 Propolis -bee glue
12 Honokiol
11 EGCG (Epigallocatechin Gallate)
10 Coenzyme Q10
10 Allicin (mainly Garlic)
10 Vitamin C (Ascorbic Acid)
9 Crocetin
9 Dandelion Root
9 Luteolin
9 Magnetic Fields
9 Moringa oleifera
8 Melatonin
8 Selenium
8 chitosan
8 Sulforaphane (mainly Broccoli)
8 Fisetin
8 Urolithin
7 Apigenin (mainly Parsley)
7 α-Bisabolol / Chamomile oil
7 Cinnamon
7 Magnolol
6 Radiotherapy/Radiation
6 Ashwagandha(Withaferin A)
6 Betulinic acid
6 Boron
6 Capsaicin
6 Chrysin
6 Cichoric acid / Chicoric acid
6 Chemotherapy
6 Piperine
5 Beta-Caryophyllene
5 Thymol-Thymus vulgaris
5 Carnosine
5 Centella asiatica / Gotu kola → asiaticoside
5 Vitamin E
5 Carvone
5 Pterostilbene
5 Selenite (Sodium)
4 Cisplatin
4 doxorubicin
4 beta-carotene(VitA)
4 Bacopa monnieri
4 Caffeic acid
4 Caffeic Acid Phenethyl Ester (CAPE)
4 Date Fruit Extract
4 D-limonene
4 Ellagic acid
4 Shilajit/Fulvic Acid
4 Shikonin
3 Anthocyanins
3 Ascorbyl Palmitate
3 Hydroxycinnamic-acid
3 Vitamin K2
3 Carica papaya leaf extract
3 Cucurbitacin
3 Ginkgo biloba
3 Geraniol
3 HydroxyTyrosol
3 Lecithin
3 Naringin
3 Rutin
3 Salvia officinalis
3 Taurine
3 Ursolic acid
2 1,8-Cineole
2 Anethole/trans-Anethole
2 Fennel Oil/Foeniculum vulgare
2 Aromatherapy
2 Vitamin B6,pyridoxine
2 Chocolate
2 Echinacea
2 Eurycomanone
2 Ginger/6-Shogaol/Gingerol
2 Huperzine A/Huperzia serrata
2 Juglone
2 Methylene blue
2 Nimbolide
2 Phenylbutyrate
2 Phenethyl isothiocyanate
2 Propyl gallate
2 α-Santalol/Sandalwood oil
2 Shankhpushpi
2 Vitamin B1/Thiamine
2 Vitamin B12
2 Folic Acid, Vit B9
2 Vitamin D3
1 5-fluorouracil
1 Astragalus
1 Citric Acid
1 Ajoene (compound of Garlic)
1 alpha Linolenic acid
1 DTS(dibenzyl trisulphide) from Anamu
1 Artemisinin
1 Aloe anthraquinones
1 beta-glucans
1 Baicalin
1 Biochanin A
1 Cannabidiol
1 Boswellia (frankincense)
1 Bruteridin(bergamot juice)
1 Carnosic acid
1 Celastrol
1 Chlorophyllin
1 Choline
1 methotrexate
1 Copper and Cu NanoParticles
1 Deguelin
1 diet Methionine-Restricted Diet
1 Fenbendazole
1 flavonoids
1 Gallic acid
1 Germacranolide
1 hydrogen sulfide
1 Lutein
1 Methyl salicylate / Sweet Birch oil
1 Magnetic Field Rotating
1 Methylsulfonylmethane
1 N-Acetyl-Cysteine
1 nicotinamide adenine dinucleotide
1 Oleocanthal
1 Phosphatidylserine
1 Psoralidin
1 Perilla
1 Sulfasalazine
1 Sesame seeds and Oil
1 Iron
1 Spermidine
1 Terpinen-4-ol / Tea Tree Oil
1 cetuximab
1 Ginseng
1 Aflavin-3,3′-digallate
1 Dichloroacetate
1 probiotics
1 Zinc
Query results interpretion may depend on "conditions" listed in the research papers.
Such Conditions may include : 
  -low or high Dose
  -format for product, such as nano of lipid formations
  -different cell line effects
  -synergies with other products 
  -if effect was for normal or cancerous cells

Filter Conditions: Pro/AntiFlg:%  IllCat:%  CanType:%  Cells:%  prod#:%  Target#:1103  State#:%  Dir#:%
  wNotes=0  sortOrder:rid,rpid

 

Home Page