MMP9 Cancer Research Results

MMP9, MMP9: Click to Expand ⟱
Source: HalifaxProj(suppress)
Type:
Matrix metalloproteinase-9 (MMP-9) is an enzyme that plays a significant role in the degradation of extracellular matrix components.
MMP-9 facilitates the breakdown of the extracellular matrix, which can enable cancer cells to invade surrounding tissues and spread to distant sites (metastasis).
Elevated levels of MMP-9 have been associated with poor prognosis in several cancers, including breast, lung, and colorectal cancers.
MMP2 and MMP9: two enzymes are critical to tumor invasion.
Scientific Papers found: Click to Expand⟱
1673- PBG,    An Insight into Anticancer Effect of Propolis and Its Constituents: A Review of Molecular Mechanisms
- Review, Var, NA
TumCP↓, Apoptosis↑, TumCCA↑, MALAT1↓, P53↑, RadioS↑, OS↑, ROS↑, NF-kB↓, p65↑, MMP↓, ROS↑, MMP9↓, β-catenin/ZEB1↓, Vim↓, E-cadherin↓, VEGF↓, EMT↓,
1662- PBG,    The immunomodulatory and anticancer properties of propolis
- Review, Var, NA
IL6↓, IL12↓, IL10↑, CSCs↓, PAK1↓, VEGF↓, MMP2↓, MMP9↓, NF-kB↓, Hif1a↓, ChemoSen↑, RadioS↑,
4918- PEITC,    Nutritional Sources and Anticancer Potential of Phenethyl Isothiocyanate: Molecular Mechanisms and Therapeutic Insights
- Review, Var, NA
Apoptosis↑, TumCP↓, angioG↓, TumMeta↓, NF-kB↓, Akt↓, MAPK↓, *BioAv↓, ROS↑, lipid-P↑, AIF↑, Cyt‑c↑, DR4↑, DR5↑, TumCCA↑, JAK↓, STAT3↓, MMP2↓, MMP9↓, PKCδ↓, Hif1a↓, JNK↓, Mcl-1↓, COX2/PTGS2↓, MMP↓, Casp3↑, ChemoSen↑, *BioAv↓, Half-Life↓,
4931- PEITC,    Phenethyl isothiocyanate (PEITC) suppresses prostate cancer cell invasion epigenetically through regulating microRNA-194
- in-vitro, Pca, LNCaP - in-vitro, Pca, PC3
Risk↓, miR-194↑, TumCI↓, MMP2↓, MMP9↓, BMP2↓, *chemoPv↑,
5187- PEITC,    Phenethyl Isothiocyanate Inhibits Migration and Invasion of Human Gastric Cancer AGS Cells through Suppressing MAPK and NF-κB Signal Pathways
- in-vitro, GC, AGS
TumMeta↓, ERK↓, MKK7↓, PKCδ↓, Rho↓, uPA↓, MMP2↓, MMP9↓, RAS↓, VEGF↓, FAK↓, iNOS↓, COX2/PTGS2↓, TumCP↓,
5220- PG,  TMZ,    Propyl Gallate Exerts an Antimigration Effect on Temozolomide-Treated Malignant Glioma Cells through Inhibition of ROS and the NF- κ B Pathway
- in-vitro, GBM, U87MG
TumCMig↓, MMP2↓, MMP9↓, NF-kB↓, ROS↑, selectivity↑,
1163- PI,    The Effect of Piperine on MMP-9, VEGF, and E-cadherin Expression in Breast Cancer MCF-7 Cell Line
- in-vitro, BC, MC38
tumCV↓, VEGF↓, MMP9↓, E-cadherin↓,
3587- PI,    Piperine: A review of its biological effects
- Review, Park, NA - Review, AD, NA
*hepatoP↑, *Inflam↓, *neuroP↑, *antiOx↑, *angioG↑, *cardioP↑, *BioAv↑, *P450↓, *Synergy↑, *BioEnh↑, E-cadherin↓, ER(estro)↓, MMP2↓, MMP9↓, VEGF↓, cMyc↓, BAX↑, P53↑, TumCG↓, OS↑, *cognitive↑, *GSK‐3β↓, *GSH↑, *Casp3↓, *Casp9↓, *Cyt‑c↓, *lipid-P↓, *motorD↑, *AChE↓, *memory↑, *cardioP↑, *ROS↓, *PPARγ↑, *ALAT↓, *AST↓, *ALP↓, *AMPK↑, *5HT↑, *SIRT1↑, *eff↑, *antiAll↑,
3597- PI,    Chronic diseases, inflammation, and spices: how are they linked?
- Review, AD, NA - Review, Park, NA - Review, Var, NA
*NF-kB↓, *MAPK↓, *AP-1↓, *COX2/PTGS2↓, *NOS2↓, *IL1β↓, *TNF-α↓, *PGE2↓, *STAT3↓, *IL10↑, *IL4↓, *IL5↓, P53↑, MMP9↓, MMP2↓, cMyc↓, VEGF↓, STAT3↓, survivin↓, p65↓, *antiAll↑,
4222- PI,    Potential of piperine for neuroprotection in sepsis-associated encephalopathy
- in-vivo, Sepsis, NA
*MMP9↓, *BDNF↑, *memory↑, *neuroP↑,
5209- PI,    Piperine depresses the migration progression via downregulating the Akt/mTOR/MMP-9 signaling pathway in DU145 cells
- in-vitro, Pca, DU145
TumCP↓, TumCMig↓, Apoptosis↑, p‑Akt↓, MMP9↓, p‑mTOR↓, TumMeta↓, *antiOx↓, *Inflam↓, *hepatoP↑, *Imm↑, *AntiCan↑,
2973- PL,    The Natural Alkaloid Piperlongumine Inhibits Metastatic Activity and Epithelial-to-Mesenchymal Transition of Triple-Negative Mammary Carcinoma Cells
- in-vitro, BC, MDA-MB-231 - in-vitro, BC, 4T1
MMP2↓, MMP9↓, IL6↓, E-cadherin↑, ROS↑, EMT↓, Zeb1↓, Slug↓, TumMeta↓, selectivity↑, MMP2↓, GSH↓,
2946- PL,    Piperlongumine, a potent anticancer phytotherapeutic: Perspectives on contemporary status and future possibilities as an anticancer agent
- Review, Var, NA
ROS↑, GSH↓, DNAdam↑, ChemoSen↑, RadioS↑, BioEnh↑, selectivity↑, BioAv↓, eff↑, p‑Akt↓, mTOR↓, GSK‐3β↓, β-catenin/ZEB1↓, HK2↓, Glycolysis↓, Cyt‑c↑, Casp9↑, Casp3↑, Casp7↑, cl‑PARP↑, TrxR↓, ER Stress↑, ATF4↝, CHOP/DDIT3↑, Prx4↑, NF-kB↓, cycD1/CCND1↓, CDK4↓, CDK6↓, p‑RB1↓, RAS↓, cMyc↓, TumCCA↑, selectivity↑, STAT3↓, NRF2↑, HO-1↑, PTEN↑, P-gp/ABCB1↓, MDR1↓, MRP1/ABCC1↓, survivin↓, Twist↓, AP-1↓, Sp1/3/4↓, STAT1↓, STAT6↓, SOX4↑, XBP-1↑, P21↑, eff↑, Inflam↓, COX2/PTGS2↓, IL6↓, MMP9↓, TumMeta↓, TumCI↓, ICAM-1↓, CXCR4↓, VEGF↓, angioG↓, Half-Life↝, BioAv↑,
2948- PL,    The promising potential of piperlongumine as an emerging therapeutics for cancer
- Review, Var, NA
tumCV↓, TumCP↓, TumCI↓, angioG↓, EMT↓, TumMeta↓, *hepatoP↑, *lipid-P↓, *GSH↑, cardioP↑, CycB/CCNB1↓, cycD1/CCND1↓, CDK2↓, CDK1↓, CDK4↓, CDK6↓, PCNA↓, Akt↓, mTOR↓, Glycolysis↓, NF-kB↓, IKKα↓, JAK1↓, JAK2↓, STAT3↓, ERK↓, cFos↓, Slug↓, E-cadherin↑, TOP2↓, P53↑, P21↑, Bcl-2↓, BAX↑, Casp3↑, Casp7↑, Casp8↑, p‑HER2/EBBR2↓, HO-1↑, NRF2↑, BIM↑, p‑FOXO3↓, Sp1/3/4↓, cMyc↓, EGFR↓, survivin↓, cMET↓, NQO1↑, SOD2↑, TrxR↓, MDM2↓, p‑eIF2α↑, ATF4↑, CHOP/DDIT3↑, MDA↑, Ki-67↓, MMP9↓, Twist↓, SOX2↓, Nanog↓, OCT4↓, N-cadherin↓, Vim↓, Snail↓, TumW↓, TumCG↓, HK2↓, RB1↓, IL6↓, IL8↓, SOD1↑, RadioS↑, ChemoSen↑, toxicity↓, Sp1/3/4↓, GSH↓, SOD↑,
7431- Poly,    Garlic peel extract as an antioxidant inhibits triple‐negative breast tumor growth and angiogenesis by inhibiting cyclooxygenase‐2 expression
- vitro+vivo, BC, 4T1
other↝, AntiTum↑, Dose↝, TumCG↓, ALAT↓, AST↓, hepatoP↑, COX2/PTGS2↓, MMP2↓, MMP9↓,
1994- PTL,    Parthenolide Inhibits Tumor Cell Growth and Metastasis in Melanoma A2058 Cells
- in-vitro, Melanoma, A2058 - in-vitro, Nor, L929
tumCV↓, selectivity?, ROS?, BAX↑, TumCCA?, MMP2↓, MMP9↓, TumCMig↓, Synergy↑,
4694- PTS,    Pterostilbene as a Multifaceted Anticancer Agent: Molecular Mechanisms, Therapeutic Potential and Future Directions
- Review, Var, NA
BioAv↑, AntiCan↑, Casp↑, TumCCA↑, angioG↓, TumMeta↓, MMP9↓, VEGF↓, CSCs↓, CD44↓, cMyc↓, ChemoSen↑, mTOR↓,
4692- PTS,    Pterostilbene Suppresses both Cancer Cells and Cancer Stem-Like Cells in Cervical Cancer with Superior Bioavailability to Resveratrol
- in-vitro, Cerv, HeLa
TumCG↓, TumMeta↓, TumCCA↑, ROS↑, Apoptosis↑, MMP2↓, MMP9↓, CD133↓, OCT4↓, SOX2↓, Nanog↓, STAT3↓, CSCs↓,
4689- PTS,    Pterostilbene Suppresses both Cancer Cells and Cancer Stem-Like Cells in Cervical Cancer with Superior Bioavailability to Resveratrol
- in-vitro, Cerv, HeLa
eff↑, TumCCA↑, ROS↑, MMP2↓, MMP9↓, CSCs↓, CD133↓, OCT4↓, SOX2↓, Nanog↓, STAT3↓, BioAv↑, TumCI↓, ROS↑, Apoptosis↑,
3930- PTS,    A Review of Pterostilbene Antioxidant Activity and Disease Modification
- Review, Var, NA - Review, adrenal, NA - Review, Stroke, NA
*BioAv↑, *antiOx↑, *neuroP↑, *Inflam↓, *ROS↓, *H2O2↓, *GSH↑, *GPx↑, *GSR↑, *SOD↑, TumCG↓, PTEN↑, HGF/c-Met↓, PI3K↓, Akt↓, NF-kB↓, TumMeta↓, MMP2↓, MMP9↓, Ki-67↓, Casp3↑, MMP↓, H2O2↑, ROS↑, ChemoSen↑, *cardioP↑, *CDK2↓, *CDK4↓, *cycE/CCNE↓, *cycD1/CCND1↓, *RB1↓, *PCNA↓, *CREB↑, *GABA↑, *memory↑, *IGF-1↑, *ERK↑, TIMP1↑, BAX↑, Cyt‑c↑, Diablo↑, SOD2↑,
2343- QC,    Pharmacological Activity of Quercetin: An Updated Review
- Review, Nor, NA
*ROS↓, *GSH↑, *Catalase↑, *SOD↑, *MDA↓, *GPx↑, *Copper↓, *Iron↓, Apoptosis↓, TumCCA↑, MMP2↓, MMP9↓, GlucoseCon↓, lactateProd↓, PKM2↓, GLUT1↓, LDHA↓, ROS↑,
2341- QC,    Quercetin suppresses the mobility of breast cancer by suppressing glycolysis through Akt-mTOR pathway mediated autophagy induction
- in-vitro, BC, MCF7 - in-vitro, BC, MDA-MB-231 - in-vivo, NA, NA
MMP2↓, MMP9↓, VEGF↓, Glycolysis↓, lactateProd↓, PKM2↓, GLUT1↓, LDHA↓, TumAuto↑, Akt↓, mTOR↓, TumMeta↓, MMP3↓, eff↓, GlucoseCon↓, lactateProd↓, TumAuto↑, LC3B-II↑,
3353- QC,    Quercetin triggers cell apoptosis-associated ROS-mediated cell death and induces S and G2/M-phase cell cycle arrest in KON oral cancer cells
- in-vitro, Oral, KON - in-vitro, Nor, MRC-5
tumCV↓, selectivity↑, TumCCA↑, TumCMig↓, TumCI↓, Apoptosis↑, TumMeta↓, Bcl-2↓, BAX↑, TIMP1↑, MMP2↓, MMP9↓, *Inflam↓, *neuroP↑, *cardioP↑, p38↓, MAPK↓, Twist↓, P21↓, cycD1/CCND1↓, Casp3↑, Casp9↑, p‑Akt↓, p‑ERK↓, CD44↓, CD24↓, ChemoSen↑, MMP↓, Cyt‑c↑, AIF↑, ROS↑, Ca+2↑, Hif1a↓, VEGF↓,
3368- QC,    The potential anti-cancer effects of quercetin on blood, prostate and lung cancers: An update
- Review, Var, NA
*Inflam↓, *antiOx↑, *AntiCan↑, Casp3↓, p‑Akt↓, p‑mTOR↓, p‑ERK↓, β-catenin/ZEB1↓, Hif1a↓, AntiAg↓, VEGFR2/KDR/Flk1↓, EMT↓, EGFR↓, MMP2↓, MMP↓, TumMeta↓, MMPs↓, Akt↓, Snail↓, N-cadherin↓, Vim↓, E-cadherin↑, STAT3↓, TGF-β↓, ROS↓, P53↑, BAX↑, PKCδ↓, PI3K↓, COX2/PTGS2↓, cFLIP↓, cycD1/CCND1↓, cMyc↓, IL6↓, IL10↓, Cyt‑c↑, TumCCA↑, DNMTs↓, HDAC↓, ac‑H3↑, ac‑H4↑, Diablo↑, Casp3↑, Casp9↑, PARP1↑, Synergy↑, PTEN↑, VEGF↓, NO↓, iNOS↓, ChemoSen↑, Synergy↑, Synergy↑, Synergy↑, uPA↓, CXCR4↓, CXCL12↓, CLDN2↓, CDK6↓, MMP9↓, TSP-1↑, Ki-67↓, PCNA↓, ROS↑, ER Stress↑,
3369- QC,    Pharmacological basis and new insights of quercetin action in respect to its anti-cancer effects
- Review, Pca, NA
FAK↓, TumCCA↑, p‑pRB↓, CDK2↑, CycB/CCNB1↓, CDK1↓, EMT↓, PI3K↓, MAPK↓, Wnt↓, ROS↑, miR-21↑, Akt↓, NF-kB↓, FasL↑, Bak↑, BAX↑, Bcl-2↓, Casp3↓, Casp9↑, P53↑, p38↑, MAPK↑, Cyt‑c↑, PARP↓, CHOP/DDIT3↑, ROS↓, LDH↑, GRP78/BiP↑, ERK↑, MDA↓, SOD↑, GSH↑, NRF2↑, VEGF↓, PDGF↓, EGF↓, FGF↓, TNF-α↓, TGF-β↓, VEGFR2/KDR/Flk1↓, EGFR↓, FGFR1↓, mTOR↓, cMyc↓, MMPs↓, LC3B-II↑, Beclin-1/ATG6↑, IL1β↓, CRP↓, IL10↓, COX2/PTGS2↓, IL6↓, TLR4↓, Shh↓, HER2/EBBR2↓, NOTCH↓, DR5↑, HSP70/HSPA5↓, CSCs↓, angioG↓, MMP2↓, MMP9↓, IGFBP3↑, uPA↓, uPAR↓, RAS↓, Raf↓, TSP-1↑,
3370- QC,    Quercetin downregulates matrix metalloproteinases 2 and 9 proteins expression in prostate cancer cells (PC-3)
- in-vitro, Pca, PC3
MMP2↓, MMP9↓,
3372- QC,  FIS,  KAE,    Anticancer Potential of Selected Flavonols: Fisetin, Kaempferol, and Quercetin on Head and Neck Cancers
- Review, HNSCC, NA
ROCK1↑, TumCCA↓, HSPs↓, RAS↓, ROS↑, Ca+2↑, MMP↓, Cyt‑c↑, Endon↑, MMP9↓, MMP2↓, MMP7↓, MMP-10↓, VEGF↓, NF-kB↓, p65↓, iNOS↓, COX2/PTGS2↓, uPA↓, PI3K↓, FAK↓, MEK↓, ERK↓, JNK↓, p38↓, cJun↓, FOXO3↑,
3374- QC,    Therapeutic effects of quercetin in oral cancer therapy: a systematic review of preclinical evidence focused on oxidative damage, apoptosis and anti-metastasis
- Review, Oral, NA - Review, AD, NA
α-SMA↓, α-SMA↑, TumCP↓, tumCV↓, TumVol↓, TumCI↓, TumMeta↓, TumCMig↓, ROS↑, Apoptosis↑, BioAv↓, *neuroP↑, *antiOx↑, *Inflam↓, *Aβ↓, *cardioP↑, MMP↓, Cyt‑c↑, MMP2↓, MMP9↓, EMT↓, MMPs↓, Twist↓, Slug↓, Ca+2↑, AIF↑, Endon↑, P-gp/ABCB1↓, LDH↑, HK2↓, PKA↓, Glycolysis↓, GlucoseCon↓, lactateProd↓, GRP78/BiP↑, Casp12↑, CHOP/DDIT3↑,
4286- RES,    Neuroprotective Properties of Resveratrol and Its Derivatives—Influence on Potential Mechanisms Leading to the Development of Alzheimer’s Disease
- Review, AD, NA
*neuroP↑, *Inflam↓, *antiOx↑, *GSH↑, *HO-1↑, *iNOS↓, *BDNF↑, *p‑CREB↑, *PKA↑, *Bcl-2↑, *BAX↓, *IL1β↓, *IL6↓, *MMP9↓, *memory↑, *AMPK↑, *PGC-1α↓, *NF-kB↓, *Aβ↓, *SIRT1↑, *p‑tau↓, *PP2A↑, *lipid-P↓, *NLRP3↓, *BACE/β-secretase↓,
4657- RES,    Resveratrol, cancer and cancer stem cells: A review on past to future
- Review, Var, NA
CSCs↓, CD133↓, Shh↓, Twist↓, Snail↓, MMP2↓, MMP9↓, Smad1↓, CD44↓, ALDH1A1↓, OCT4↓, Nanog↓, STAT3↓, survivin↓, cycD1/CCND1↓, COX2/PTGS2↓, cMyc↓,
2566- RES,    A comprehensive review on the neuroprotective potential of resveratrol in ischemic stroke
- Review, Stroke, NA
*neuroP↑, *NRF2↑, *SIRT1↑, *PGC-1α↑, *FOXO↑, *HO-1↑, *NQO1↑, *ROS↓, *BP↓, *BioAv↓, *Half-Life↝, *AMPK↑, *GSK‐3β↓, *eff↑, *AntiAg↑, *BBB↓, *Inflam↓, *MPO↓, *TLR4↓, *NF-kB↓, *p65↓, *MMP9↓, *TNF-α↓, *IL1β↓, *PPARγ↑, *MMP↑, *ATP↑, *Cyt‑c∅, *mt-lipid-P↓, *H2O2↓, *HSP70/HSPA5↝, *Mets↝, *eff↑, *eff↑, *motorD↑, *MDA↓, *NADH:NAD↑, eff↑, eff↑,
3086- RES,    Resveratrol inhibits the tumor migration and invasion by upregulating TET1 and reducing TIMP2/3 methylation in prostate carcinoma cells
- in-vitro, Pca, LNCaP - in-vitro, Pca, PC3 - in-vitro, Pca, DU145
TET1↑, TumCMig↓, TumCI↓, TIMP2↑, TIMP3↑, MMP2↓, MMP9↓,
3083- RES,    Resveratrol suppresses breast cancer cell invasion by inactivating a RhoA/YAP signaling axis
- in-vitro, BC, MDA-MB-231 - in-vitro, BC, MDA-MB-468
YAP/TEAD↓, Rho↓, FAK↓, MMP9↓, ChemoSen↑, RAS↓, ROCK1↓, TumCI↓, TumMeta↓,
3081- RES,    Resveratrol and p53: How are they involved in CRC plasticity and apoptosis?
- Review, CRC, NA
NF-kB↓, FAK↓, Ki-67↓, MMP9↓, CSCs↓, CD44↓, CD133↓, ALDH1A1↓, EMT↓, ChemoSen↑, Hif1a↓, ITGB1↓, Inflam↓,
3079- RES,    Therapeutic role of resveratrol against hepatocellular carcinoma: A review on its molecular mechanisms of action
- Review, Var, NA
angioG↓, TumMeta↓, ChemoSen↑, NADPH↑, SIRT1↑, NF-kB↓, NLRP3↓, Dose↝, COX2/PTGS2↓, MMP9↓, PGE2↓, TIMP1↑, TIMP2↑, Sp1/3/4↓, p‑JNK↓, uPAR↓, ROS↓, CXCR4↓, IL6↓, Gli1↓, *ROS↓, *GSTs↑, *SOD↑, *Catalase↑, *GPx↑, *lipid-P↓, *GSH↑, Synergy↑, Synergy↑, Synergy↑,
3078- RES,    The Effects of Resveratrol on Prostate Cancer through Targeting the Tumor Microenvironment
- Review, Pca, NA
*ROS↓, ROS↑, DNAdam↑, Apoptosis↑, Hif1a↑, Casp3↑, Casp9↑, Cyt‑c↑, Dose↝, MMPs↓, MMP2↓, MMP9↓, EMT↓, E-cadherin↑, N-cadherin↓, AR↓,
3077- RES,    Resveratrol attenuates matrix metalloproteinase-9 and -2-regulated differentiation of HTB94 chondrosarcoma cells through the p38 kinase and JNK pathways
- in-vitro, Chon, HTB94
MMP2↓, MMP9↓, SOX9↑, MMPs↓, p‑p38↑, p‑JNK↓, NF-kB↓, HO-1↓,
3076- RES,    Resveratrol for targeting the tumor microenvironment and its interactions with cancer cells
- Review, Var, NA
IL6↓, MMPs↓, MMP2↓, MMP9↓, BioAv↓, Half-Life↑, BioAv↑, Dose↝, angioG↓, IL10↓, VEGF↓, NF-kB↓, COX2/PTGS2↓, SIRT1↑, Wnt↓, cMyc↓, STAT3↓, PTEN↑, ROS↑, RadioS↑, Hif1a↓, E-cadherin↓, Vim↓, angioG↓,
3089- RES,    The Role of Resveratrol in Cancer Therapy
- Review, Var, NA
angioG↓, VEGF↓, EGFR↓, FGF↑, TumCMig↓, TumCI↓, TIMP1↑, MMP2↓, MMP9↓, NF-kB↓, Hif1a↓, PI3K↓, Akt↓, MAPK↓, EMT↓, AR↓,
3092- RES,    Resveratrol in breast cancer treatment: from cellular effects to molecular mechanisms of action
- Review, BC, MDA-MB-231 - Review, BC, MCF7
TumCP↓, tumCV↓, TumCI↓, TumMeta↓, *antiOx↑, *cardioP↑, *Inflam↓, *neuroP↑, *Keap1↓, *NRF2↑, *ROS↓, p62↓, IL1β↓, CRP↓, VEGF↓, Bcl-2↓, MMP2↓, MMP9↓, FOXO4↓, POLD1↓, CK2↓, MMP↓, ROS↑, Apoptosis↑, TumCCA↑, Beclin-1/ATG6↓, Ki-67↓, ATP↓, GlutMet↓, PFK↓, TGF-β↓, SMAD2↓, SMAD3↓, Vim?, Snail↓, Slug↓, E-cadherin↑, EMT↓, Zeb1↓, Fibronectin↓, IGF-1↓, PI3K↓, Akt↓, HO-1↑, Synergy↑, PD-1↓, CD8+↑, Th1 response↑, CSCs↓, RadioS↑, SIRT1↑, Hif1a↓, mTOR↓,
3094- RES,    Resveratrol suppresses growth of cancer stem-like cells by inhibiting fatty acid synthase
- in-vitro, BC, MCF7 - in-vitro, BC, MDA-MB-231
CSCs↓, tumCV↓, FASN↑, BNIP3↑, *cardioP↑, *antiOx↑, NF-kB↓, COX2/PTGS2↓, MMP9↓, IGF-1↓, ERK↓, lipid-P↓, CD24↓,
3095- RES,    Resveratrol suppresses migration, invasion and stemness of human breast cancer cells by interfering with tumor-stromal cross-talk
- in-vitro, BC, NA
TumCP↓, TumCMig↓, TumCI↓, cycD1/CCND1↓, cMyc↓, MMP2↓, MMP9↓, SOX2↓, Akt↓, STAT3↓, α-SMA↓,
3099- RES,    Resveratrol and cognitive decline: a clinician perspective
- Review, Nor, NA - NA, AD, NA
*antiOx↑, *ROS↓, *cognitive↑, *neuroP↑, *SIRT1↑, *AMPK↑, *GPx↑, *HO-1↑, *GSK‐3β↑, *COX2/PTGS2↓, *PGE2↓, *NF-kB↓, *NO↓, *Casp3↓, *MMP3↓, *MMP9↓, *MMP↑, *GSH↑, *other↑, *BioAv↑, *memory↑, *GlutMet↑, *BioAv↓, *Half-Life↓, *toxicity∅,
3063- RES,    Resveratrol: A Review of Pre-clinical Studies for Human Cancer Prevention
- Review, Var, NA
*Inflam↓, *antiOx↑, *AntiAg↑, *chemoPv↑, ChemoSen↑, BioAv↑, Half-Life↝, COX2/PTGS2↓, cycD1/CCND1↓, CDK2↓, CDK4↓, CDK6↓, P21↑, MMP9↓, NF-kB↓, Telomerase↓, PSA↓, MAPK↑, P53↑,
7150- RES,    Modulation of the PI3K/Akt signaling pathway by resveratrol in cancer: molecular mechanisms and therapeutic opportunity
- Review, Var, NA
AntiTum↑, PI3K↓, Akt↓, *AntiAge↑, *SIRT1↑, *lipid-P↓, *ROS↓, *BioAv↓, *NRF2↑, *HO-1↑, SOD↑, HDAC1↓, PTEN↑, P53↑, TumCCA↑, TumCI↓, TumMeta↓, EMT↓, MMPs↓, MMP9↓, angioG↓, VEGF↓, EGFR↓, FGF21↓, HIF-1↓, *neuroP↑, *cardioP↑, BMPs↑, ROS↑, Vim↓, N-cadherin↓, MMP3↓, MMP13↓, E-cadherin↑, Ki-67↓,
3612- RES,    Resveratrol in Alzheimer's disease: a review of pathophysiology and therapeutic potential
- Review, AD, NA
*other↑, *Aβ↓, *Inflam↓, *NF-kB↓, *neuroP↑, *HO-1↑, *lipid-P↓, *COX2/PTGS2↓, *AMPK↑, *Catalase↑, *SOD↑, *GSR↑, *ROS↓, *MMP9↓, *cognitive↑, *SIRT1↑, *IL1β↓, *IL6↓,
3613- RES,    Resveratrol for Alzheimer's disease
- Review, AD, NA
*SIRT1↑, *BioAv↝, *toxicity↓, *ROS↓, *antiOx↑, *Aβ↓, *MMP9↓, *TNF-α↓,
3028- RosA,    Network pharmacology mechanism of Rosmarinus officinalis L.(Rosemary) to improve cell viability and reduces apoptosis in treating Alzheimer’s disease
- in-vitro, AD, HT22 - in-vivo, NA, NA
*Aβ↓, *Apoptosis↓, *antiOx↑, *neuroP↑, *Ingr↝, *IGF-1↑, *MMP9↑, *Src↓, *MAPK↓, *MMP↑,
3010- RosA,    Exploring the mechanism of rosmarinic acid in the treatment of lung adenocarcinoma based on bioinformatics methods and experimental validation
- in-vitro, Lung, A549 - in-vivo, NA, NA
TumCG↓, Ki-67↓, FABP4↑, PPARα↑, ROS↑, Apoptosis↑, MMP9↓, IGFBP3↓, MMP2↓, EMT↓, TumCI↓, PI3K↓, Akt↓, mTOR↓, Gli1↓, PPARγ↑, Cyt‑c↑,
3003- RosA,    Comprehensive Insights into Biological Roles of Rosmarinic Acid: Implications in Diabetes, Cancer and Neurodegenerative Diseases
- Review, Var, NA - Review, AD, NA - Review, Park, NA
*Inflam↓, *antiOx↑, *neuroP↑, *IL6↓, *IL1β↓, *NF-kB↓, *PGE2↓, *COX2/PTGS2↓, *MMP↑, *memory↑, *ROS↓, *Aβ↓, *HMGB1↓, TumCG↓, MARK4↓, Zeb1↓, MDM2↓, BNIP3↑, ASC↑, NLRP3↓, PI3K↓, Akt↓, Casp1↓, E-cadherin↑, STAT3↓, TLR4↓, MMP↓, ICAM-1↓, AMPK↓, IL6↑, MMP2↓, Warburg↓, Bcl-xL↓, Bcl-2↓, TumCCA↑, EMT↓, TumMeta↓, mTOR↓, HSP27↓, Casp3↑, GlucoseCon↓, lactateProd↓, VEGF↓, p‑p65↓, GIT1↓, FOXM1↓, cycD1/CCND1↓, CDK4↓, MMP9↓, HDAC2↓,

Showing Research Papers: 351 to 400 of 448
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* indicates research on normal cells as opposed to diseased cells
Total Research Paper Matches: 448

Pathway results for Effect on Cancer / Diseased Cells:


NA, unassigned(tgid=0) ⓘ

NA↓, 1,  

Redox & Oxidative Stress(tgid=1) ⓘ

antiOx↓, 3,   antiOx↑, 10,   antiOx⇅, 1,   Catalase↓, 5,   Catalase↑, 3,   Copper↓, 1,   Copper↑, 1,   frataxin↑, 1,   GPx↓, 2,   GPx↑, 4,   GPx4↓, 6,   GSH↓, 23,   GSH↑, 5,   GSR↑, 2,   GSTs↓, 1,   GSTs↑, 2,   H2O2↓, 1,   H2O2↑, 5,   HO-1↓, 9,   HO-1↑, 14,   HO-2↓, 1,   Iron↑, 3,   Keap1↓, 1,   lipid-P?, 1,   lipid-P↓, 4,   lipid-P↑, 13,   MDA↓, 5,   MDA↑, 5,   MPO↓, 1,   NOX4↓, 1,   NQO1↓, 1,   NQO1↑, 3,   NRF2↓, 13,   NRF2↑, 16,   NRF2⇅, 1,   NRF2↝, 1,   p‑NRF2↓, 1,   Prx↓, 1,   Prx4↑, 1,   PrxII↓, 1,   RNS↑, 1,   ROS?, 2,   ROS↓, 26,   ROS↑, 170,   ROS⇅, 7,   ROS∅, 1,   i-ROS↓, 2,   i-ROS↑, 2,   mt-ROS↑, 1,   SOD↓, 6,   SOD↑, 7,   SOD1↓, 1,   SOD1↑, 2,   SOD2↓, 1,   SOD2↑, 3,   TBARS↑, 1,   Thiols↓, 1,   Trx1↑, 1,   TrxR↓, 7,   xCT/SLC7A11↓, 1,  

Metal & Cofactor Biology(tgid=2) ⓘ

Ferritin↓, 1,   IronCh↑, 2,   Tf↓, 1,   TfR1/CD71↓, 1,  

Mitochondria & Bioenergetics(tgid=3) ⓘ

ADP:ATP↑, 2,   Bfl-1↓, 1,   CDC2↓, 7,   CDC25↓, 10,   compI↓, 1,   compIII↓, 1,   compV↓, 1,   EGF↓, 5,   ETC↓, 3,   mitResp↓, 1,   mitResp↑, 1,   MKK7↓, 1,   mtDam↑, 8,   OCR↓, 3,   mt-OXPHOS↓, 1,   PDH↝, 1,   PINK1↑, 1,   SIRT3↓, 2,   SIRT3↑, 3,  

Core Metabolism/Glycolysis(tgid=4) ⓘ

12LOX↓, 3,   5LO↓, 6,   ACADS/SCAD↓, 1,   ACC↑, 1,   ALAT↓, 6,   ALAT↝, 1,   AMPK↓, 2,   AMPK↑, 20,   AMPK↝, 1,   p‑AMPK↑, 2,   p‑AMT/GCST/T-protein↑, 1,   ATP↓, 13,   mt-ATP↓, 1,   CAIX/CA9↑, 1,   ECAR↓, 1,   ECAR↝, 1,   ENO1↓, 1,   FABP4↑, 1,   FASN↓, 3,   FASN↑, 1,   GAPDH↓, 2,   GLO-I↓, 1,   glucoNG↓, 1,   glucose↓, 1,   GlucoseCon↓, 9,   GlutMet↓, 2,   Glycolysis↓, 23,   GSK‐3β↓, 11,   GSK‐3β↑, 2,   p‑GSK‐3β↓, 3,   HK1↓, 1,   HK2↓, 11,   lactateProd↓, 9,   LDHA↓, 6,   LDL↓, 1,   lipidLev↓, 1,   NADPH↓, 3,   NADPH↑, 3,   O-Glc↓, 1,   PDK1 / PDPK1?, 2,   PDK1 / PDPK1↓, 7,   p‑PDK1 / PDPK1↓, 1,   PDK3↑, 1,   PFK↓, 1,   PIP3↑, 1,   PKM2↓, 8,   PKM2↑, 1,   PLA2↓, 1,   p‑S6↓, 1,   SIRT1↓, 6,   SIRT1↑, 9,   SIRT2↑, 1,   SREBP1/SREBF1↓, 2,   SREBP2↓, 1,   Warburg↓, 4,  

Cell Death(tgid=5) ⓘ

AIF↑, 10,   APAF1↑, 4,   Apoptosis?, 1,   Apoptosis↓, 4,   Apoptosis↑, 143,   ASC↑, 1,   ASK1↑, 1,   BAD↓, 3,   BAD↑, 5,   Bak↑, 5,   BAX↓, 2,   BAX↑, 94,   BAX⇅, 1,   BAX↝, 1,   Bax:Bcl2↑, 22,   Bcl-2↓, 104,   Bcl-2↑, 3,   Bcl-xL↓, 35,   BID↓, 2,   BID↑, 6,   p‑BID↓, 1,   BIM↑, 5,   BNIP3↑, 3,   BNIP3↝, 1,   Casp↓, 1,   Casp↑, 25,   Casp∅, 1,   cl‑Casp↑, 1,   Casp1↓, 1,   Casp1↑, 1,   Casp12?, 1,   Casp12↑, 2,   Casp2↑, 1,   Casp3↓, 5,   Casp3↑, 114,   Casp3∅, 1,   cl‑Casp3↑, 15,   proCasp3↑, 1,   Casp6↑, 1,   Casp7↑, 12,   cl‑Casp7↑, 1,   Casp8↑, 29,   Casp8∅, 1,   cl‑Casp8↑, 4,   proCasp8↑, 2,   Casp9↓, 1,   Casp9↑, 76,   p‑Casp9↑, 1,   cl‑Casp9↑, 8,   proCasp9↓, 1,   proCasp9↑, 1,   cFLIP↓, 4,   Cyt‑c↓, 1,   Cyt‑c↑, 62,   mt-Cyt‑c↓, 1,   Diablo↑, 12,   DR5↑, 22,   Endon↑, 2,   FADD↑, 4,   Fap1↓, 1,   Fas↓, 1,   Fas↑, 20,   FasL↓, 1,   FasL↑, 8,   FasL⇅, 1,   Ferroptosis↑, 7,   GranB/GZMB↝, 1,   GSDME↑, 1,   HEY1↓, 2,   IAP1↓, 16,   IAP2/BIRC3↓, 6,   ICAD↓, 1,   ICD↑, 1,   iNOS↓, 19,   Mcl-1?, 1,   Mcl-1↓, 27,   p‑Mcl-1↓, 1,   MDM2↓, 9,   MDM2↑, 1,   MOMP↑, 2,   Necroptosis↑, 1,   necrosis↑, 2,   NOXA↑, 3,   p38↓, 13,   p38↑, 13,   p‑p38↓, 4,   p‑p38↑, 4,   p‑p38↝, 1,   Perforin↝, 1,   PUMA↓, 1,   PUMA↑, 6,   Pyro↑, 4,   RIP1↑, 1,   RIP3↑, 1,   survivin↓, 53,   TNFR 1↑, 1,   TRAIL↑, 3,   TRAILR↑, 2,   TumCD↓, 1,   TumCD↑, 7,   XIAP↓, 26,   XIAP↑, 1,   YAP/TEAD↓, 5,  

Kinase & Signal Transduction(tgid=6) ⓘ

Akt↓, 134,   Akt↑, 4,   p‑Akt↓, 43,   AKT1↓, 2,   Akt2↓, 1,   CaMKII ↓, 1,   CIP2A↓, 2,   CK2↓, 4,   cMET↓, 2,   p‑cMET↓, 1,   cSrc↓, 3,   EGFR↓, 34,   p‑EGFR↓, 3,   ERK↓, 53,   ERK↑, 8,   p‑ERK↓, 23,   p‑ERK↑, 1,   p‑ERK↝, 1,   FGFR1↓, 3,   FGFR2↓, 1,   FOXD3↑, 2,   HER2/EBBR2↓, 13,   p‑HER2/EBBR2↓, 1,   HGF/c-Met↓, 2,   Hippo↑, 1,   IGF-1R↓, 6,   IGFR↓, 1,   IKKα↓, 10,   IKKα↝, 1,   p‑IKKα↓, 2,   IκB↓, 1,   p‑IκB↓, 3,   p‑IκB↑, 1,   JAK↓, 6,   p‑JAK↓, 1,   JAK1↓, 4,   p‑JAK1↓, 1,   JAK2↓, 17,   p‑JAK2↓, 3,   p‑JAK3↓, 1,   JNK↓, 12,   JNK↑, 18,   p‑JNK↓, 5,   p‑JNK↑, 2,   p‑JNK↝, 1,   p‑MAP2K1/MEK1↓, 1,   MAPK↓, 35,   MAPK↑, 13,   p‑MAPK↓, 2,   MARK4↓, 2,   MEK↓, 5,   p‑MEK↓, 2,   MKK4↓, 1,   mTOR↓, 67,   mTOR↝, 1,   p‑mTOR↓, 11,   mTORC2↓, 2,   mTORC2↑, 1,   p70S6↓, 1,   P70S6K↓, 2,   p‑P70S6K↓, 1,   p‑P90RSK↑, 1,   PDGFR-BB↓, 1,   p‑PDGFR-BB↓, 1,   PDGFRA↓, 1,   PI3K↓, 106,   PI3K↑, 1,   p‑PI3K↓, 8,   p‑PI3K↑, 1,   PI3K/Akt↓, 4,   PKA↓, 2,   PKCδ↓, 14,   p‑PKCδ↓, 1,   PTEN↓, 1,   PTEN↑, 29,   Raf↓, 5,   e-Raf↓, 1,   c-Raf↓, 1,   RAS↓, 12,   p‑S6K↓, 1,   SHP1↑, 2,   Sp1/3/4↓, 12,   Sp1/3/4↑, 1,   Src↓, 2,   p‑Src↓, 1,   STAT↓, 4,   p‑STAT2↓, 1,   STAT3↓, 76,   STAT3↑, 3,   p‑STAT3↓, 13,   p‑STAT3↑, 3,   STAT5↓, 3,   STAT6↓, 2,   TSC2↑, 1,  

Transcription & Epigenetics(tgid=7) ⓘ

ATF3↑, 1,   ATF4↓, 1,   ATF4↑, 6,   ATF4↝, 1,   CBP↓, 1,   cJun↓, 8,   cJun↑, 1,   p‑cJun↓, 1,   cMyc↓, 40,   cMyc↑, 1,   p‑cMyc↑, 1,   DNMT1↓, 6,   DNMTs↓, 7,   EZH2↓, 6,   FOXM1↓, 4,   FOXO↑, 3,   FOXO1↓, 3,   FOXO1↑, 1,   FOXO3↓, 3,   FOXO3↑, 8,   FOXO3↝, 1,   p‑FOXO3↓, 1,   FOXO4↓, 2,   FOXO4↑, 1,   H3↑, 1,   ac‑H3↓, 1,   ac‑H3↑, 2,   H4↑, 1,   ac‑H4↓, 1,   ac‑H4↑, 2,   HATs↓, 7,   HATs↑, 1,   HDAC↓, 18,   HDAC1↓, 5,   HDAC10↓, 1,   HDAC2↓, 3,   HDAC3↓, 2,   HDAC4↓, 1,   HDAC6↓, 2,   HDAC8↓, 1,   HES1↓, 3,   JPT1/HN1↓, 1,   LINC01116↓, 1,   Matr↓, 1,   miR-106b↓, 1,   miR-107↑, 2,   miR-10b-5p↓, 1,   miR-126↓, 1,   miR-133a-3p↑, 1,   miR-139-5p↑, 2,   miR-149↑, 1,   miR-155↓, 5,   miR-155↑, 1,   miR-17↓, 1,   miR-182-5p↓, 1,   miR-194↑, 1,   miR-195↑, 1,   miR-200b↑, 2,   miR-200c↓, 1,   miR-203↑, 1,   miR-21↓, 8,   miR-21↑, 2,   miR-210↑, 1,   miR-221↓, 1,   miR-224↓, 2,   miR-25-5p↑, 1,   miR-27a-3p↓, 1,   miR-27a-3p↑, 1,   miR-301a-3p↓, 1,   miR-340↓, 2,   miR-34a↑, 5,   miR-34b-5p↑, 1,   miR-384↑, 2,   miR-422a↑, 2,   miR-592↑, 1,   MTA2↓, 1,   Myc↓, 5,   n-MYC↓, 2,   NDRG1↑, 1,   OCT4↓, 15,   other↓, 3,   other↑, 1,   other↝, 4,   other∅, 1,   PAX2↓, 1,   PhotoS↑, 1,   SOX2↓, 11,   SOX4↓, 2,   SOX4↑, 1,   SOX9?, 1,   SOX9↓, 2,   SOX9↑, 1,   TCF-4↓, 2,   tumCV↓, 28,   ZBTB10↑, 1,  

Protein Folding & ER Stress(tgid=8) ⓘ

ATF6↑, 1,   CHOP/DDIT3↓, 1,   CHOP/DDIT3↑, 17,   eIF2α↓, 1,   p‑eIF2α↑, 3,   ER Stress↓, 1,   ER Stress↑, 33,   Erlin1↑, 1,   GRP78/BiP↓, 2,   GRP78/BiP↑, 12,   GRP78/BiP↝, 1,   HSF1↓, 1,   HSP27↓, 4,   HSP27↝, 1,   HSP70/HSPA5↓, 7,   HSP70/HSPA5↑, 1,   HSP70/HSPA5↝, 1,   HSP90↓, 11,   HSPs↓, 1,   IRE1↑, 5,   PDI↑, 1,   PERK↑, 3,   Proteasome↓, 1,   SERPINH1/HSP47↓, 1,   UPR↓, 1,   UPR↑, 4,   XBP-1↓, 1,   XBP-1↑, 1,  

Autophagy & Lysosomes(tgid=9) ⓘ

ATG5↓, 1,   ATG5↑, 2,   ATG7↑, 1,   Beclin-1/ATG6↓, 5,   Beclin-1/ATG6↑, 10,   CTSB↓, 2,   CTSD↓, 2,   CTSK↓, 1,   LC3‑Ⅱ/LC3‑Ⅰ↓, 1,   LC3A↑, 1,   LC3B↓, 1,   LC3B-II↓, 1,   LC3B-II↑, 4,   LC3II↓, 3,   LC3II↑, 8,   LC3s↓, 1,   LC3s↑, 1,   p62↓, 6,   p62↑, 2,   PARK2↑, 1,   TumAuto↓, 1,   TumAuto↑, 31,   TumAuto⇅, 1,  

DNA Damage & Repair(tgid=10) ⓘ

ATM?, 1,   ATM↑, 2,   BRCA1↓, 1,   BRCA1↑, 1,   p‑BRCA1↑, 1,   BRCA2↑, 1,   DFF45↓, 2,   DNAdam↓, 3,   DNAdam↑, 40,   DNArepair↓, 2,   DNArepair↑, 1,   ERCC1↓, 1,   ERCC3↑, 1,   hTERT/TERT↓, 11,   MGMT↓, 1,   p16↑, 4,   P53?, 2,   P53↓, 2,   P53↑, 75,   P53↝, 1,   p‑P53↑, 1,   PARP↓, 2,   PARP↑, 16,   cl‑PARP↓, 1,   cl‑PARP↑, 50,   PARP1↑, 1,   PCNA↓, 24,   POLD1↓, 1,   SIRT6↓, 2,   SIRT6↑, 1,   Telomerase↓, 14,   TOP1↓, 7,   TOP2↓, 6,   TOP2↑, 2,   TP53↑, 3,   TRF2↓, 1,   UHRF1↓, 1,   XRCC1↓, 1,   γH2AX↓, 1,   γH2AX↑, 8,   γH2AX↝, 1,  

Cell Cycle & Senescence(tgid=11) ⓘ

CC(CDKs/cyclins)↓, 1,   CDK1↓, 11,   p‑CDK1↓, 1,   CDK1/2/5/9↓, 1,   CDK2↓, 40,   CDK2↑, 3,   CDK4↓, 51,   CDK4↑, 1,   p‑CDK4↓, 1,   CDK4/6↓, 1,   CDK6↓, 24,   CDK6↑, 1,   CDK8↓, 1,   CDKN1C/p57↓, 1,   CDKN1C/p57↑, 1,   CHK1↓, 3,   p‑CHK1↑, 1,   Chk2↓, 2,   Cyc↓, 2,   cycA1/CCNA1↓, 9,   cycA1/CCNA1↑, 2,   CycB/CCNB1↓, 19,   CycB/CCNB1↑, 1,   cycD1/CCND1↓, 85,   cycD1/CCND1↑, 1,   p‑cycD1/CCND1↓, 1,   CycD3↓, 3,   cycE/CCNE↓, 23,   E2Fs↓, 5,   GADD45A↑, 1,   Ki-67↓, 28,   MAD↓, 1,   P21↓, 4,   P21↑, 55,   p27/CDKN1B↓, 2,   p27/CDKN1B↑, 21,   pRB↓, 2,   pRB↑, 1,   p‑pRB↓, 1,   RB1↓, 1,   RB1↑, 2,   p‑RB1↓, 5,   Securin↓, 1,   TumCCA?, 1,   TumCCA↓, 10,   TumCCA↑, 148,  

Proliferation, Differentiation & Cell State(tgid=12) ⓘ

4E-BP1↓, 1,   ALDH↓, 6,   ALDH1A1↓, 3,   BMP2↓, 2,   BMPs↑, 1,   CD133↓, 10,   CD133↑, 1,   CD24↓, 4,   CD34↓, 1,   cFos↓, 8,   p‑cFos↓, 1,   cMYB↓, 1,   CSCs↓, 38,   CSCs↑, 1,   Diff↓, 1,   Diff↑, 3,   EIF4E↓, 1,   FGF↓, 3,   FGF↑, 1,   Gli↓, 2,   Gli1↓, 9,   HH↓, 8,   IGF-1↓, 9,   IGF-2↓, 1,   IGFBP3↓, 1,   IGFBP3↑, 2,   JAG1↓, 1,   Jun↓, 1,   Ki-67↓, 28,   Let-7↑, 6,   LRP6↓, 1,   p‑LRP6↓, 1,   mTORC1↓, 4,   p‑mTORC1↓, 1,   Nanog↓, 11,   Nestin↓, 2,   NICD↓, 1,   NOTCH↓, 19,   NOTCH1↓, 12,   NOTCH1↑, 3,   NOTCH1↝, 1,   NOTCH2↓, 1,   NOTCH3↓, 2,   p300↓, 2,   Piezo1↑, 1,   PTCH1↓, 2,   Shh↓, 7,   Smo↓, 3,   STAT1↓, 1,   p‑STAT1↓, 1,   Sufu↓, 1,   TAZ↓, 1,   TOPflash↓, 1,   TumCG↓, 67,   TumCG↑, 2,   TumCP?, 1,   TumCP↓, 127,   TumCP↑, 2,   tyrosinase↓, 2,   URGCP/URG4↓, 1,   Wnt↓, 42,   Wnt/(β-catenin)↓, 5,   ZFX↓, 1,  

Migration(tgid=13) ⓘ

AEG1↓, 1,   AntiAg?, 1,   AntiAg↓, 1,   AntiAg↑, 2,   AP-1↓, 20,   AP-1↝, 1,   ATPase↓, 1,   AXL↓, 2,   CA↓, 3,   Ca+2↓, 1,   Ca+2↑, 32,   Ca+2↝, 1,   i-Ca+2?, 1,   i-Ca+2↑, 1,   CAFs/TAFs↓, 2,   cal2↓, 1,   CCN2/CTGF↓, 2,   Cdc42↑, 1,   Cofilin↓, 1,   COL1A1↓, 1,   COL3A1↓, 1,   DLC1↑, 1,   E-cadherin↓, 13,   E-cadherin↑, 69,   EMMPRIN↓, 1,   EMT↓, 101,   EMT↑, 3,   EpCAM↓, 4,   F-actin↓, 2,   FAK↓, 22,   FAK↑, 2,   p‑FAK↓, 5,   fascin↓, 1,   Fibronectin↓, 8,   GIT1↓, 1,   GLI2↓, 2,   IQGAP3↓, 1,   ITGA1∅, 1,   ITGA5↓, 3,   ITGA5∅, 1,   ITGB1↓, 4,   ITGB1∅, 1,   ITGB3↓, 1,   ITGB3∅, 1,   ITGB4∅, 1,   KAI1/CD82↑, 1,   LAMs↓, 1,   LIMK2↓, 1,   MALAT1↓, 1,   MET↓, 1,   MMP-10↓, 2,   MMP1↓, 13,   MMP11↓, 1,   MMP13↓, 8,   MMP14↓, 1,   MMP16↓, 3,   MMP2?, 2,   MMP2↓, 260,   MMP2↑, 2,   MMP2⇅, 1,   MMP2↝, 1,   MMP2∅, 1,   MMP3↓, 15,   MMP7↓, 16,   MMP7∅, 1,   MMP9?, 2,   MMP9↓, 399,   MMP9↑, 9,   MMP9⇅, 1,   MMP9↝, 1,   MMP9∅, 1,   pro‑MMP9↓, 1,   MMPs↓, 27,   MTA1↓, 1,   MUC4↓, 2,   N-cadherin↓, 46,   NCAM↓, 1,   PAI-1/SERPINE1↓, 1,   PAK1↓, 2,   PDGF↓, 7,   Rac1↓, 1,   RECK↑, 1,   Rho↓, 6,   ROCK1↓, 7,   ROCK1↑, 1,   Sharpin↓, 1,   Slug?, 1,   Slug↓, 20,   Smad1↓, 1,   Smad1↑, 1,   SMAD2↓, 1,   p‑SMAD2↓, 2,   SMAD3↓, 2,   SMAD3↑, 1,   p‑SMAD3↓, 2,   SMAD4↓, 2,   Snail?, 2,   Snail↓, 37,   Snail↑, 1,   STAC2↓, 1,   TET1↓, 1,   TET1↑, 3,   TGF-β↓, 21,   TGF-β↑, 2,   TGF-β1↓, 1,   TIMP1↓, 7,   TIMP1↑, 23,   TIMP2↓, 5,   TIMP2↑, 17,   TIMP3↑, 2,   TSP-1↑, 3,   TumCA↓, 7,   TumCA↑, 1,   TumCI↓, 135,   TumCI↑, 2,   TumCMig↓, 126,   TumCMig↑, 1,   TumMeta↓, 94,   TumMeta↑, 6,   TumPF↓, 1,   Twist↓, 28,   Twist↑, 1,   uPA↓, 40,   uPAR↓, 7,   Vim?, 1,   Vim↓, 59,   Zeb1↓, 18,   ZEB2↓, 3,   ZEB2↑, 1,   α-SMA↓, 4,   α-SMA↑, 1,   α-tubulin↑, 3,   β-catenin/ZEB1↓, 49,   β-catenin/ZEB1↑, 1,  

Angiogenesis & Vasculature(tgid=14) ⓘ

angioG↓, 97,   angioG↑, 1,   angioS↑, 1,   CCN1/CYR61↓, 1,   CD31/PECAM-1↓, 3,   ECM/TCF↓, 1,   Endoglin↑, 1,   eNOS↓, 3,   HIF-1↓, 4,   Hif1a↓, 57,   Hif1a↑, 2,   Hif1a↝, 1,   LOX1↓, 1,   NO↓, 7,   NO↑, 1,   PHDs↓, 1,   TXA2↓, 1,   VCAM-1↓, 4,   VEGF↓, 148,   VEGF↑, 1,   VEGFR1↓, 5,   VEGFR2/KDR/Flk1↓, 19,  

Barriers & Transport(tgid=15) ⓘ

BBB↑, 4,   BBB∅, 1,   CLDN1↓, 2,   CLDN2↓, 1,   EPR↑, 5,   EPR↝, 1,   GLUT1↓, 9,   GLUT1↑, 1,   GLUT3↑, 1,   GLUT4↓, 1,   MMP↓, 75,   MMP↑, 1,   MMP∅, 1,   MPT↑, 5,   NHE1↓, 2,   TRPM7↓, 1,   TRPV1↑, 3,   ZO-1↑, 4,  

Immune & Inflammatory Signaling(tgid=16) ⓘ

CCR7↓, 1,   CD4+↓, 1,   CD4+↑, 1,   CD44↓, 15,   CD8+↑, 1,   p‑cDC2↓, 1,   COX1↓, 5,   COX2/PTGS2↓, 107,   COX2/PTGS2↑, 2,   COX2/PTGS2↝, 1,   CXCL1↓, 1,   CXCL12↓, 2,   CXCL16↓, 1,   CXCR2↓, 2,   CXCR4↓, 23,   CXCR4↑, 1,   DR4↑, 8,   FOXP3↓, 2,   FOXP3↑, 1,   Gal-3↓, 1,   HMGB1↓, 4,   ICAM-1↓, 12,   IFN-γ↓, 2,   IFN-γ↑, 2,   Igs↑, 1,   IL-1Ra↑, 1,   IL1↓, 7,   IL1↑, 2,   IL10↓, 6,   IL10↑, 3,   IL12↓, 4,   IL12↑, 1,   IL17↓, 1,   IL18↓, 2,   IL18↑, 1,   IL1R2↑, 1,   IL1RL1/ST2↑, 1,   IL1α↓, 2,   IL1β↓, 15,   IL1β↑, 2,   IL2↓, 4,   IL2↑, 4,   IL22↓, 1,   IL23↓, 1,   IL33↑, 1,   IL4↓, 2,   IL4↑, 2,   IL6↓, 53,   IL6↑, 1,   IL8↓, 13,   IL8↑, 2,   Imm↑, 2,   Imm↝, 3,   Inflam↓, 27,   IRAK1↓, 1,   M2 MC↓, 2,   MCP1/CCL2↓, 7,   MIP2↓, 1,   mPGES-1↓, 2,   NF-kB?, 1,   NF-kB↓, 168,   NF-kB↑, 1,   NF-kB↝, 1,   p‑NF-kB↓, 2,   p‑NF-kB↑, 1,   NK cell↑, 3,   NLRP3↓, 3,   NLRP3↑, 2,   p50↓, 3,   p65↓, 11,   p65↑, 1,   p‑p65↓, 3,   PD-1↓, 2,   PD-L1↓, 8,   PD-L1↑, 1,   PGE2↓, 25,   PSA↓, 5,   PSA∅, 1,   RAGE↓, 1,   T-Cell↑, 1,   Th1 response↑, 2,   TLR2↓, 1,   TLR4↓, 3,   TLR4↝, 1,   TNF-α↓, 34,   TNF-α↑, 7,   TNF-α∅, 1,   TNFRSF25/DR3/APO3/LARD/TRAMP/WSL1↑, 1,   TRAF1↓, 1,   Treg lymp↓, 1,  

Cellular Microenvironment(tgid=17) ⓘ

TAMS↝, 1,  

Synaptic & Neurotransmission(tgid=18) ⓘ

5HT↓, 1,   PTN↓, 1,  

Protein Aggregation(tgid=19) ⓘ

XO↓, 1,  

Hormonal & Nuclear Receptors(tgid=20) ⓘ

AhR↓, 1,   AhR↑, 1,   AhR↓, 1,   AR↓, 12,   AR↑, 1,   CYP19↓, 1,   ER-α36↓, 2,   ER(estro)↓, 1,   ERα/ESR1↓, 1,   FGF21↓, 1,   GR↑, 1,   PPARα↓, 2,   PPARα↑, 1,   PPARα↝, 1,   cl‑PPARα↓, 1,   PPARγ↓, 3,   PPARγ↑, 8,   RANKL↓, 2,  

Drug Metabolism & Resistance(tgid=21) ⓘ

BioAv↓, 40,   BioAv↑, 41,   BioAv↝, 10,   BioEnh↑, 2,   CBR1↓, 1,   ChemoSen↓, 2,   ChemoSen↑, 122,   CompStab↓, 1,   CompStab↝, 2,   CYP1A1↓, 3,   CYP1A1↑, 2,   CYP1A2↓, 1,   CYP1B1↑, 1,   DDS↑, 1,   Dose?, 3,   Dose↓, 3,   Dose↑, 6,   Dose↝, 36,   Dose∅, 9,   eff?, 1,   eff↓, 17,   eff↑, 62,   eff↝, 10,   GSTA1↑, 1,   Half-Life↓, 9,   Half-Life↑, 4,   Half-Life↝, 9,   Half-Life∅, 1,   MDR1↓, 7,   MRP1/ABCC1↓, 3,   MRP1/ABCC1↝, 1,   P-gp/ABCB1↓, 17,   P-gp/ABCB1⇅, 1,   P450↓, 1,   RadioS↑, 37,   selectivity?, 2,   selectivity↑, 45,   selectivity∅, 1,   Synergy↑, 88,   TET2↑, 1,  

Clinical Biomarkers(tgid=22) ⓘ

AFP↓, 1,   ALAT↓, 6,   ALAT↝, 1,   ALP↓, 2,   ALP↝, 1,   AR↓, 12,   AR↑, 1,   ascitic↓, 2,   AST↓, 4,   AST↝, 1,   BRCA1↓, 1,   BRCA1↑, 1,   p‑BRCA1↑, 1,   CA125↓, 1,   CRP↓, 3,   E6↓, 2,   E7↓, 2,   EGFR↓, 34,   p‑EGFR↓, 3,   ERα/ESR1↓, 1,   EZH2↓, 6,   Ferritin↓, 1,   FOXM1↓, 4,   HER2/EBBR2↓, 13,   p‑HER2/EBBR2↓, 1,   hTERT/TERT↓, 11,   IL6↓, 53,   IL6↑, 1,   LDH↓, 3,   LDH↑, 4,   Myc↓, 5,   PD-L1↓, 8,   PD-L1↑, 1,   PSA↓, 5,   PSA∅, 1,   RAGE↓, 1,   TP53↑, 3,  

Functional Outcomes(tgid=23) ⓘ

AntiCan↑, 40,   AntiCan?, 1,   antiCG↓, 1,   antiD↑, 1,   AntiDiabetic↑, 2,   antiNeop↑, 3,   AntiTum↓, 1,   AntiTum↑, 19,   cachexia↓, 2,   cardioP↑, 8,   CardioT↑, 2,   chemoP?, 1,   chemoP↑, 16,   chemoPv↑, 18,   ChemoSideEff↓, 4,   cognitive↑, 2,   hepatoP↓, 1,   hepatoP↑, 8,   neuroP↑, 5,   OS↑, 7,   Pin1↓, 1,   QoL↑, 2,   radioP↑, 7,   Remission↑, 1,   RenoP↑, 5,   Risk↓, 4,   toxicity↓, 13,   toxicity↑, 5,   toxicity↝, 6,   toxicity∅, 1,   TumVol↓, 16,   TumVol∅, 1,   TumW↓, 5,   TumW∅, 1,   Weight↑, 1,   Weight∅, 1,   Wound Healing↓, 1,  

Infection & Microbiome(tgid=24) ⓘ

Bacteria↓, 1,   GutMicro↑, 3,   GutMicro↝, 1,   Sepsis↓, 3,  

Ingredients & Constituents(tgid=25) ⓘ

Ingr↝, 1,  
Total Targets: 1037

Pathway results for Effect on Normal Cells:


Redox & Oxidative Stress(tgid=1) ⓘ

antiOx↓, 5,   antiOx↑, 77,   ARE↑, 1,   Catalase↑, 31,   Copper↓, 1,   GPx↓, 1,   GPx↑, 25,   GPx1↑, 1,   GPx3↑, 1,   GPx4↑, 1,   GSH↑, 28,   GSR↓, 1,   GSR↑, 6,   GSTs↑, 11,   H2O2↓, 5,   H2O2∅, 1,   HDL↓, 1,   HDL↑, 2,   HO-1↑, 20,   hyperG↝, 1,   Iron↓, 2,   i-Iron↓, 1,   Keap1↓, 1,   lipid-P↓, 18,   mt-lipid-P↓, 1,   MDA↓, 22,   MPO↓, 3,   MPO↑, 1,   NADH↓, 1,   NQO1↑, 3,   Nrf1↑, 1,   NRF2?, 1,   NRF2↑, 30,   Prx↑, 2,   RNS↓, 4,   ROS?, 2,   ROS↓, 86,   SOD↑, 40,   SOD1↑, 6,   SOD2↑, 3,   TAC↑, 1,   TrxR↑, 1,   xCT/SLC7A11↑, 1,  

Metal & Cofactor Biology(tgid=2) ⓘ

IronCh↑, 4,   Mets↝, 1,  

Mitochondria & Bioenergetics(tgid=3) ⓘ

Insulin↑, 1,   mtDam↓, 1,   PGC-1α↓, 1,   PGC-1α↑, 1,  

Core Metabolism/Glycolysis(tgid=4) ⓘ

12LOX↑, 1,   5LO↓, 3,   ALAT↓, 8,   AMPK↑, 8,   ATP↑, 1,   cAMP↑, 1,   DGAT1↓, 1,   FASN↓, 1,   glucose↓, 1,   glucose↑, 1,   GlucoseCon↑, 2,   GlutMet↑, 1,   GSK‐3β↓, 4,   GSK‐3β↑, 1,   LDL↓, 3,   NAD↑, 1,   NADH:NAD↑, 1,   SIRT1↑, 11,  

Cell Death(tgid=5) ⓘ

Apoptosis↓, 4,   ASC?, 1,   BAD↓, 1,   BAX↓, 7,   Bcl-2↓, 1,   Bcl-2↑, 1,   Bcl-xL↑, 1,   Casp1↓, 1,   Casp3?, 1,   Casp3↓, 7,   Casp3∅, 1,   cl‑Casp3↓, 1,   cl‑Casp8↓, 1,   Casp9↓, 2,   Cyt‑c↓, 3,   Cyt‑c∅, 2,   Ferroptosis↓, 1,   iNOS↓, 14,   iNOS↑, 1,   necrosis↓, 1,   p38↓, 1,   p38↑, 2,   Pyro?, 1,   RIP1↓, 1,  

Kinase & Signal Transduction(tgid=6) ⓘ

Akt↓, 1,   Akt↑, 5,   p‑Akt↓, 2,   p‑Akt↑, 2,   AKT1↓, 1,   CREB↑, 1,   p‑CREB↑, 1,   ERK↓, 1,   ERK↑, 4,   p‑ERK↑, 1,   IGF-1R↓, 1,   JAK↓, 1,   JAK2↑, 1,   JNK↓, 3,   JNK↑, 1,   p‑JNK↓, 1,   p‑LIMK1↑, 1,   MAPK↓, 9,   MAPK↑, 4,   mTOR↓, 1,   mTOR↑, 2,   PDGFR-BB↓, 1,   PI3K↓, 1,   PI3K↑, 5,   PKA↑, 1,   PKCδ↑, 3,   PP2A↑, 1,   PTEN↓, 2,   PTEN↑, 1,   Src↓, 1,   STAT↓, 1,   STAT3↓, 4,   STAT3↑, 2,   p‑STAT3↑, 1,  

Transcription & Epigenetics(tgid=7) ⓘ

AntiThr↑, 3,   cJun↓, 1,   cMyc↓, 1,   p‑cMyc↑, 1,   FOXO↑, 1,   HDAC↓, 1,   HOTAIR↑, 1,   other↓, 4,   other↑, 5,   other↝, 7,   RUNX2↑, 1,  

Protein Folding & ER Stress(tgid=8) ⓘ

CHOP/DDIT3↓, 1,   ER Stress↓, 1,   GRP78/BiP↓, 1,   HSP70/HSPA5↓, 1,   HSP70/HSPA5↑, 7,   HSP70/HSPA5↝, 1,   HSPs↑, 1,   IRE1↓, 1,  

Autophagy & Lysosomes(tgid=9) ⓘ

Beclin-1/ATG6↓, 1,   p62↑, 1,  

DNA Damage & Repair(tgid=10) ⓘ

p‑BRCA1↑, 1,   DNAdam↓, 2,   p16↓, 1,   P53↓, 2,   PCNA↓, 1,  

Cell Cycle & Senescence(tgid=11) ⓘ

CDK2↓, 1,   CDK4↓, 1,   cycD1/CCND1↓, 2,   cycE/CCNE↓, 1,   E2Fs↑, 2,   P21↓, 1,   RB1↓, 1,   TumCCA↑, 1,  

Proliferation, Differentiation & Cell State(tgid=12) ⓘ

BMP2↑, 1,   cFos↑, 1,   Diff↑, 1,   IGF-1↑, 2,   neuroG↑, 3,   TumCP↓, 1,  

Migration(tgid=13) ⓘ

AntiAg↑, 10,   AP-1↓, 4,   Ca+2↓, 1,   Ca+2↑, 1,   Ca+2↝, 1,   Cartilage↑, 1,   p‑Cofilin↑, 1,   COL1↑, 1,   EMT↑, 1,   LAMs↑, 1,   p‑MLC2/MYL9↑, 1,   MMP-10↓, 1,   MMP1↓, 2,   MMP2↓, 7,   MMP2↑, 2,   MMP3↓, 3,   MMP9↓, 32,   MMP9↑, 6,   MMPs↓, 2,   MYPT1 / PPP1R12A↑, 1,   p‑MYPT1 / PPP1R12A↑, 1,   ROCK1↑, 1,   Smad1↑, 1,   SMAD3↓, 1,   TGF-β↓, 4,   TGF-β↑, 2,   TGF-β1↓, 1,   TIMP1↓, 2,   TIMP1↑, 2,   TIMP2↑, 2,   TregCell↑, 1,   TumCI↓, 1,   TumMeta↓, 1,   α-SMA↓, 5,   β-catenin/ZEB1↑, 1,  

Angiogenesis & Vasculature(tgid=14) ⓘ

angioG↓, 1,   angioG↑, 3,   CD31/PECAM-1↓, 1,   eNOS↑, 2,   HIF-1↓, 1,   Hif1a↓, 1,   Hif1a↑, 1,   LOX1↓, 1,   NO↓, 15,   NO↑, 4,   VCAM-1↓, 5,   VEGF↓, 3,   VEGF↑, 6,   p‑VEGFR2/KDR/Flk1↓, 1,  

Barriers & Transport(tgid=15) ⓘ

BBB↓, 2,   BBB↑, 14,   BBB∅, 2,   CLDN1↝, 1,   GastroP↑, 2,   GLUT1↑, 1,   GLUT2↑, 1,   GLUT3↑, 1,   GLUT4↑, 3,   MMP↑, 10,   MMP∅, 1,   MUC19↓, 1,   MUC2↓, 1,   TJ↑, 1,   TRPM7↓, 1,   ZO-1↝, 1,  

Immune & Inflammatory Signaling(tgid=16) ⓘ

CD19↑, 1,   CD4+↑, 1,   COX1↓, 4,   COX2/PTGS2↓, 34,   CXCR4↓, 1,   Eos↓, 1,   HMGB1↓, 2,   ICAM-1↓, 3,   IFN-γ↓, 1,   IFN-γ↑, 1,   IL1↓, 3,   IL10↓, 1,   IL10↑, 5,   IL12↓, 3,   IL17↓, 3,   IL18↓, 2,   IL1β↓, 25,   IL2↑, 2,   IL23↓, 1,   IL4↓, 2,   IL4↑, 2,   IL5↓, 2,   IL6↓, 31,   IL8↓, 7,   Imm↑, 12,   Inflam↓, 85,   Inflam↑, 2,   IRF3↓, 1,   MCP1/CCL2↓, 3,   MyD88↓, 1,   NeuroI↓, 1,   NF-kB↓, 45,   NK cell↑, 1,   NLRP3↓, 6,   NLRP3↑, 1,   p65↓, 1,   PGE2↓, 14,   PGE2↑, 3,   RAGE↓, 1,   SOCS-3↓, 1,   Th1 response↓, 1,   Th2↑, 2,   TLR2↓, 3,   TLR4↓, 6,   TNF-α↓, 32,   TRIF↓, 1,  

Synaptic & Neurotransmission(tgid=18) ⓘ

5HT↑, 2,   Ach↑, 1,   AChE↓, 12,   AChE↑, 1,   BChE↓, 1,   BDNF↑, 9,   GABA↑, 3,   NGF↑, 2,   PSD95↑, 1,   SNAP25↑, 1,  

Protein Aggregation(tgid=19) ⓘ

AGEs↓, 3,   Aβ↓, 15,   BACE/β-secretase↓, 5,   tau↓, 1,   p‑tau↓, 1,   β-Amyloid↓, 1,  

Hormonal & Nuclear Receptors(tgid=20) ⓘ

AHR↓, 1,   CYP19↓, 1,   PPARγ↓, 1,   PPARγ↑, 4,  

Drug Metabolism & Resistance(tgid=21) ⓘ

BioAv↓, 28,   BioAv↑, 25,   BioAv↝, 19,   BioEnh↑, 1,   CompStab↑, 1,   CYP1A1↑, 1,   CYP1A2↑, 1,   CYP2E1↓, 1,   Dose⇅, 1,   Dose↝, 8,   eff↓, 2,   eff↑, 17,   eff↝, 1,   GSTA1↑, 1,   Half-Life↓, 3,   Half-Life↝, 6,   Half-Life∅, 1,   P-gp/ABCB1↓, 1,   P450↓, 3,   Synergy↑, 5,  

Clinical Biomarkers(tgid=22) ⓘ

ALAT↓, 8,   ALP↓, 3,   AST↓, 11,   BMD↑, 1,   BP↓, 2,   BP↝, 1,   p‑BRCA1↑, 1,   CRP↓, 5,   Hcy/homoC↓, 1,   IL6↓, 31,   LDH↓, 4,   LDH↑, 1,   NOS2↓, 2,   RAGE↓, 1,  

Functional Outcomes(tgid=23) ⓘ

Analgesic↑, 2,   AntiAge↑, 4,   antiAll↑, 14,   AntiArt↑, 7,   AntiCan↓, 1,   AntiCan↑, 16,   antiCG↑, 1,   AntiDiabetic↓, 1,   AntiDiabetic↑, 15,   antiPs↑, 1,   AntiTum↑, 5,   cardioP↑, 27,   CardioT↓, 1,   chemoP↑, 4,   chemoPv↑, 3,   cognitive↓, 1,   cognitive↑, 17,   diuretic↑, 3,   hepatoP↓, 1,   hepatoP↑, 24,   Learn↑, 2,   memory↑, 18,   motorD↑, 4,   Mucositis↓, 1,   neuroP↓, 2,   neuroP↑, 61,   Obesity↓, 4,   OS↑, 1,   Pain↓, 6,   QoL↑, 1,   radioP↑, 2,   RenoP↑, 5,   Risk↓, 1,   Stroke↓, 5,   toxicity↓, 20,   toxicity↑, 1,   toxicity↝, 6,   toxicity∅, 3,   Wound Healing↑, 2,  

Infection & Microbiome(tgid=24) ⓘ

AntiBio↑, 2,   AntiFungal↓, 1,   AntiFungal↑, 2,   AntiP↑, 1,   AntiViral↑, 7,   Bacteria↓, 19,   Diar↓, 1,   GutMicro↑, 4,   Sepsis↓, 1,  

Ingredients & Constituents(tgid=25) ⓘ

Ingr↝, 3,  
Total Targets: 379

Scientific Paper Hit Count for: MMP9, MMP9
19 Resveratrol
15 Fisetin
13 Curcumin
12 Thymoquinone
11 Matrine
11 Sulforaphane (mainly Broccoli)
9 Apigenin (mainly Parsley)
9 Baicalein
9 Berberine
9 Quercetin
9 Luteolin
9 Lycopene
8 Garcinol
8 Magnetic Fields
7 Boswellia (frankincense)
7 Propolis -bee glue
7 Capsaicin
7 Magnolol
7 Morin
6 Silver-NanoParticles
6 Alpha-Lipoic-Acid
6 Artemisinin
6 Caffeic acid
6 Chrysin
6 Diindolylmethane
6 Dandelion Root
6 EGCG (Epigallocatechin Gallate)
6 Eugenol
6 Honokiol
6 Kaempferol
6 Rosmarinic acid
5 Melatonin
5 Betulinic acid
5 Ellagic acid
5 Ferulic acid
5 Formononetin
5 Gambogic Acid
5 Nimbolide
5 Piperine
4 Cisplatin
4 Cucurbitacin
4 Pterostilbene
4 Silymarin (Milk Thistle) silibinin
4 Shikonin
4 Urolithin
3 Ascorbyl Palmitate
3 Celastrol
3 Hydroxycinnamic-acid
3 D-limonene
3 Emodin
3 phytic acid, Inositol hexakisphosphate
3 Magnetic Field Rotating
3 Phenethyl isothiocyanate
3 Piperlongumine
2 1,8-Cineole
2 Sorafenib (brand name Nexavar)
2 Astragalus
2 Paclitaxel/Taxol
2 alpha Linolenic acid
2 Radiotherapy/Radiation
2 Ashwagandha(Withaferin A)
2 Baicalin
2 Berbamine
2 Biochanin A
2 Caffeic Acid Phenethyl Ester (CAPE)
2 Carvacrol
2 Thymol-Thymus vulgaris
2 Celecoxib
2 Chlorogenic acid
2 chitosan
2 Cinnamon
2 Crocetin
2 CUSP9
2 Deguelin
2 Indole-3-carbinol
2 Evodiamine
2 tamoxifen
2 Fucoidan
2 Ginkgolic acids
2 Genistein (soy isoflavone)
2 Ginger/6-Shogaol/Gingerol
2 Graviola
2 Grapeseed extract
2 Proanthocyanidins
2 Hibiscus sabdariffa
2 HydroxyTyrosol
2 Inositol
2 Ivermectin
2 Juglone
2 Licorice
2 Mushroom Chaga, Inonotus obliquus
2 Mushroom Lion’s Mane, Hericium erinaceus
2 Naringin
2 Marjoram (Origanum majorana)
2 Selenite (Sodium)
2 Vitamin C (Ascorbic Acid)
1 2-DeoxyGlucose
1 3-bromopyruvate
1 Allicin (mainly Garlic)
1 Phyllanthus emblica/Emblica officinalis/Amla / Indian Gooseberry
1 Andrographis
1 Anethole/trans-Anethole
1 Isovitexin
1 Aspirin
1 Astaxanthin
1 Beta-Caryophyllene
1 Chemotherapy
1 Brucea javanica
1 brusatol
1 Bacopa monnieri
1 borneol
1 Carnosic acid
1 NTP, Non-Thermal Plasma,Cold Atmospheric Plasma
1 Cynanbungeigenin C (CBC) and D (CBD)
1 Centella asiatica / Gotu kola → asiaticoside
1 Selenium NanoParticles
1 Carvone
1 Cyclopamine
1 Cysteamine
1 Vitamin A, Retinoic Acid
1 Folic Acid, Vit B9
1 Bortezomib
1 Flaxseed/Linseed
1 Gallic acid
1 Ginkgo biloba
1 Geraniol
1 Ginkgetin
1 Hops (Humulus lupulus)
1 Hyperoside
1 Isobavachalcone
1 Isoliquiritigenin
1 isoorientin
1 Plumbagin
1 Lactobacillus
1 Licochalcone A
1 Methylglyoxal
1 Methylsulfonylmethane
1 Myricetin
1 Niclosamide (Niclocide)
1 Propyl gallate
1 temozolomide
1 Polyphenols
1 Parthenolide
1 Sanguinarine
1 Sesame seeds and Oil
1 Salvia miltiorrhiza
1 Aflavin-3,3′-digallate
1 Turmerones
1 VitK3,menadione
Query results interpretion may depend on "conditions" listed in the research papers.
Such Conditions may include : 
  -low or high Dose
  -format for product, such as nano of lipid formations
  -different cell line effects
  -synergies with other products 
  -if effect was for normal or cancerous cells

Filter Conditions: Pro/AntiFlg:%  IllCat:%  CanType:%  Cells:%  prod#:%  Target#:203  State#:%  Dir#:%
  wNotes=0  sortOrder:rid,rpid

 

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