| Source: |
| Type: |
| Cognitive |
| 4209- | Hup, | Huperzine A, reduces brain iron overload and alleviates cognitive deficit in mice exposed to chronic intermittent hypoxia |
| - | in-vivo, | AD, | NA |
| 4213- | Hup, | Huperzine A-Liposomes Efficiently Improve Neural Injury in the Hippocampus of Mice with Chronic Intermittent Hypoxia |
| - | in-vivo, | AD, | NA |
| 7479- | Hup, | A phase II trial of huperzine A in mild to moderate Alzheimer disease |
| - | Trial, | AD, | NA |
| 3804- | Hup, | Huperzine A for Alzheimer's disease: a systematic review and meta-analysis of randomized clinical trials |
| - | Review, | AD, | NA |
| 3803- | Hup, | Huperzine A and Its Neuroprotective Molecular Signaling in Alzheimer’s Disease |
| - | Review, | AD, | NA |
| 3800- | Hup, | Role of huperzine a in the treatment of Alzheimer's disease |
| - | Review, | AD, | NA |
| 7710- | IBC, | Isobavachalcone ameliorates Alzheimer disease pathology by autophagy-mediated clearance of amyloid beta and inhibition of NLRP3 inflammasome in primary astrocytes and 5x-FAD mice |
| - | vitro+vivo, | AD, | NA |
| 7664- | IP, | GCL2505, | Administration of bifidobacteria and dietary fiber improves cognitive function by increasing short-chain fatty acid-producing bacteria and reducing inflammation |
| - | Trial, | AD, | NA |
| 7755- | ISL, | Isoliquiritigenin attenuated cognitive impairment, cerebral tau phosphorylation and oxidative stress in a streptozotocin-induced mouse model of Alzheimer's disease |
| - | in-vivo, | AD, | NA |
| 7759- | ISL, | Rad, | Isoliquiritigenin, a Bioactive Blood Component Derived from Licorice, Activates Nrf2 Enzymes to Confer Protection Against Radiation-Induced Nerve Injury |
| - | vitro+vivo, | Nor, | PC12 |
| 7784- | ISL, | Isoliquiritigenin attenuates lipopolysaccharide-induced cognitive impairment through antioxidant and anti-inflammatory activity |
| - | in-vivo, | AD, | NA |
| 7737- | isoFl, | An updated review of dietary isoflavones: Nutrition, processing, bioavailability and impacts on human health |
| - | Review, | Nor, | NA |
| 7731- | isoFl, | Long-term soy isoflavone supplementation and cognition in women: a randomized, controlled trial |
| - | Trial, | AD, | NA |
| 7865- | isoO, | Isoorientin inhibits oxidative stress to ameliorate cognitive dysfunction in type 2 diabetes mice via GSK3β/Nrf2 axis |
| - | in-vivo, | Diabetic, | NA |
| 7851- | isoO, | Isoorientin, a GSK-3β inhibitor, rescues synaptic dysfunction, spatial memory deficits and attenuates pathological progression in APP/PS1 model mice |
| - | in-vivo, | AD, | NA |
| 7879- | isoO, | Isoorientin improves scopolamine-induced cognitive impairments by restoring the cholinergic system, antioxidant defense, and p-CREB/BDNF signaling in the hippocampus and frontal cortex |
| - | in-vivo, | AD, | NA |
| 7838- | ISQ, | Protective effects of isoquercitrin on streptozotocin‐induced neurotoxicity |
| - | in-vivo, | AD, | NA |
| 7799- | ISQ, | Acer okamotoanum and isoquercitrin improve cognitive function via attenuation of oxidative stress in high fat diet- and amyloid beta-induced mice |
| - | in-vivo, | AD, | NA |
| 7821- | ISQ, | Quercitrin improved cognitive impairment through inhibiting inflammation induced by microglia in Alzheimer's disease mice |
| - | in-vivo, | AD, | NA |
| 7836- | ISQ, | An Isoquinolinium Dual Inhibitor of Cholinesterases and Amyloid β Aggregation Mitigates Neuropathological Changes in a Triple-Transgenic Mouse Model of Alzheimer's Disease |
| - | in-vivo, | AD, | NA |
| 7901- | IVT, | Isovitexin restores sevoflurane‑induced cognitive dysfunction by mediating autophagy through activation of the PGC‑1α/FNDC5 signaling pathway |
| - | in-vivo, | Nor, | NA |
| 4007- | K+, | The increased potassium intake improves cognitive performance and attenuates histopathological markers in a model of Alzheimer's disease |
| - | in-vivo, | AD, | NA |
| 4013- | K+, | Apamin Improves Prefrontal Nicotinic Impairment in Mouse Model of Alzheimer's Disease |
| - | in-vitro, | AD, | NA |
| 7827- | KAE, | MBS, | Neuroprotective Potential of Mung Bean (Vigna radiata L.) Polyphenols in Alzheimer's Disease: A Review |
| - | Review, | AD, | NA |
| 8054- | KAE, | Kaempferol Improves Alzheimer's Disease by Inhibiting Neuronal Ferroptosis via Activating GPX4/AKR1C3 Signaling Pathway |
| - | vitro+vivo, | AD, | NA |
| 8219- | LCA, | Licochalcone A Ameliorates Cognitive Dysfunction in an Alzheimer's Disease Model by Inhibiting Endoplasmic Reticulum Stress-Mediated Apoptosis |
| - | in-vivo, | AD, | NA |
| 8220- | LCA, | Licochalcone a enhances cognitive resilience in APP/PS1 Mice by modulating glucose metabolism, Aβ burden, and neuroinflammation |
| - | in-vivo, | AD, | NA |
| 8234- | LCA, | Licochalcone A: A Potential Multitarget Drug for Alzheimer’s Disease Treatment |
| - | Review, | AD, | NA |
| 8228- | LCA, | Detection and pharmacokinetics of licochalcone A in brains of neuroinflammatory mouse model |
| - | in-vivo, | AD, | NA |
| 8274- | LE, | Research on the Antiaging Activity of Licorice Water Extract in Aging Mice via Antioxidation, Neuronal Protection, Gut Microbiota Restoration, and PI3K/AKT/mTOR Modulation |
| - | in-vivo, | Nor, | NA |
| 8278- | LE, | Glycyrrhiza glabra (Licorice): A Comprehensive Review on Its Phytochemistry, Biological Activities, Clinical Evidence and Toxicology |
| - | Review, | Var, | NA |
| 3706- | LEC, | Lecithin for dementia and cognitive impairment |
| - | Review, | AD, | NA |
| 8145- | LF, | Neuroprotective Effects of Lactoferrin in Alzheimer's and Parkinson's Diseases: A Narrative Review |
| - | Review, | AD, | NA | - | Review, | Park, | NA |
| 8144- | LF, | A pilot study on the effect of lactoferrin on Alzheimer's disease pathological sequelae: Impact of the p-Akt/PTEN pathway |
| - | Human, | AD, | NA |
| 8311- | lign, | The Power of Lignans: Plant Compounds with Multifaceted Health-Promoting Effects |
| - | Review, | Nor, | NA |
| 8329- | LIN, | Microglial-targeting induced by intranasal linalool during neurological protection postischemia |
| - | in-vivo, | Stroke, | NA | - | in-vivo, | AD, | NA |
| 8382- | LT, | Luteolin as a dietary flavonoid for brain health: modulating neuroinflammation and cognitive decline in neurodegenerative disorders |
| - | Review, | AD, | NA | - | Review, | Park, | NA |
| 8379- | LT, | Luteolin and neuroinflammation: a multi-target therapeutic strategy for central nervous system disorders |
| - | Review, | Var, | NA | - | Review, | AD, | NA | - | Review, | Stroke, | NA |
| 8388- | LT, | Untargeted metabolomics reveals the mechanisms of luteolin and exercise combination treatment against cognitive impairments in AD mice through modulating autophagy |
| - | in-vivo, | AD, | NA |
| - | in-vivo, | AD, | NA |
| 4293- | LT, | Regulatory Role of NF-κB on HDAC2 and Tau Hyperphosphorylation in Diabetic Encephalopathy and the Therapeutic Potential of Luteolin |
| - | in-vivo, | Diabetic, | NA |
| 4292- | LT, | Luteolin for neurodegenerative diseases: a review |
| - | Review, | AD, | NA | - | Review, | Park, | NA | - | Review, | MS, | NA | - | Review, | Stroke, | NA |
| 8351- | Lut, | Zeax, | Lutein and Zeaxanthin Influence Brain Function in Older Adults: A Randomized Controlled Trial |
| - | Trial, | AD, | NA |
| 8352- | Lut, | Zeax, | The effects of lutein and zeaxanthin on resting state functional connectivity in older Caucasian adults: a randomized controlled trial |
| - | Trial, | AD, | NA |
| 8353- | Lut, | Effect of Omega-3 Fatty Acids, Lutein/Zeaxanthin, or Other Nutrient Supplementation on Cognitive Function: The AREDS2 Randomized Clinical Trial |
| - | Trial, | AD, | NA |
| 4195- | Lut, | Zeax, | Low Xanthophylls, Retinol, Lycopene, and Tocopherols in Grey and White Matter of Brains with Alzheimer’s Disease |
| - | Human, | AD, | NA |
| 4194- | Lut, | Zeax, | Effect of macular pigment carotenoids on cognitive functions: A systematic review |
| - | Review, | AD, | NA |
| 4193- | Lut, | Zeax, | Effects of a Lutein and Zeaxanthin Intervention on Cognitive Function: A Randomized, Double-Masked, Placebo-Controlled Trial of Younger Healthy Adults |
| - | Trial, | Nor, | NA |
| 4192- | Lut, | Zeax, | Lutein and Zeaxanthin Supplementation Improves Dynamic Visual and Cognitive Performance in Children: A Randomized, Double-Blind, Parallel, Placebo-Controlled Study |
| - | Trial, | Nor, | NA |
| 3981- | Lut, | Zeax, | VitE, | Omega-3 fatty acid, carotenoid and vitamin E supplementation improves working memory in older adults: A randomised clinical trial |
| - | Trial, | AD, | NA |
Query results interpretion may depend on "conditions" listed in the research papers. Such Conditions may include : -low or high Dose -format for product, such as nano of lipid formations -different cell line effects -synergies with other products -if effect was for normal or cancerous cells
Filter Conditions: Pro/AntiFlg:% IllCat:% CanType:% Cells:% prod#:% Target#:557 State#:% Dir#:%
wNotes=0 sortOrder:rid,rpid