BioAv Cancer Research Results

BioAv, bioavailability: Click to Expand ⟱
Source:
Type: measurement
Bioavailability (usually in %) absorbed by the body.
Scientific Papers found: Click to Expand⟱
1605- EA,    Ellagic Acid and Cancer Hallmarks: Insights from Experimental Evidence
- Review, Var, NA
*BioAv↓, antiOx↓, Inflam↓, TumCP↓, TumCCA↑, cycD1/CCND1↓, cycE/CCNE↓, P53↑, P21↑, COX2/PTGS2↓, NF-kB↓, Akt↑, NOTCH↓, CDK2↓, CDK6↓, JAK↓, STAT3↓, EGFR↓, p‑ERK↓, p‑Akt↓, p‑STAT3↓, TGF-β↓, SMAD3↓, CDK6↓, Wnt/(β-catenin)↓, Myc↓, survivin↓, CDK8↓, PKCδ↓, tumCV↓, RadioS↑, eff↑, MDM2↓, XIAP↓, p‑RB1↓, PTEN↑, p‑FAK↓, Bax:Bcl2↑, Bcl-xL↓, Mcl-1↓, PUMA↑, NOXA↑, MMP↓, Cyt‑c↑, ROS↑, Ca+2↝, Endoglin↑, Diablo↑, AIF↑, iNOS↓, Casp9↑, Casp3↑, cl‑PARP↑, RadioS↑, Hif1a↓, HO-1↓, HO-2↓, SIRT1↓, selectivity↑, Dose∅, NHE1↓, Glycolysis↓, GlucoseCon↓, lactateProd↓, PDK1 / PDPK1?, PDK1 / PDPK1?, ECAR↝, COX1↓, Snail↓, Twist↓, cMyc↓, Telomerase↓, angioG↓, MMP2↓, MMP9↓, VEGF↓, Dose↝, PD-L1↓, eff↑, SIRT6↑, DNAdam↓,
1608- EA,    Ellagic Acid from Hull Blackberries: Extraction, Purification, and Potential Anticancer Activity
- in-vitro, Cerv, HeLa - in-vitro, Liver, HepG2 - in-vitro, BC, MCF7 - in-vitro, Lung, A549 - in-vitro, Nor, HUVECs
eff↑, Dose∅, *BioAv↑, selectivity↑, TumCP↓, Casp↑, PTEN↑, TSC1↑, mTOR⇅, Akt↓, PDK1 / PDPK1↓, E6↓, E7↓, DNAdam↑, ROS↑, *BioAv↓, *BioEnh↑, *Half-Life∅,
1611- EA,    Targeting Myeloperoxidase Activity and Neutrophil ROS Production to Modulate Redox Process: Effect of Ellagic Acid and Analogues
- in-vitro, Mal, NA
*BioAv↓, eff↑, *BioAv↓, ROS↑,
1615- EA,    Absorption, metabolism, and antioxidant effects of pomegranate (Punica granatum l.) polyphenols after ingestion of a standardized extract in healthy human volunteers
- Human, Nor, NA
*BioAv∅, *ROS∅,
6801- EA,    A radiotherapeutic paradox: ellagic acid sensitizes tumors while attenuating radiation-induced myocardial injury
- vitro+vivo, BC, 4T1
TumCCA↑, CDK4↓, RadioS↑, TumCG↓, *radioP↑, *cardioP↑, *antiOx↑, *ROS↓, Dose↑, selectivity↑, BioAv↓,
6604- Ech,    Echinacea alkamide disposition and pharmacokinetics in humans after tablet ingestion
- Human, Nor, NA
*BioAv↑, *Half-Life↝, *Dose↝, Dose?,
7222- EGb 761,    Ginkgo biloba extract EGb 761® in the symptomatic treatment of mild-to-moderate dementia: a profile of its use
- Review, AD, NA
*cognitive↑, *toxicity↓, *Dose↝, *BioAv↑, *Half-Life↑, *neuroP↑, *Half-Life↝, *Dose↝, *other↝, *eff↑,
3201- EGCG,    Epigallocatechin Gallate (EGCG): Pharmacological Properties, Biological Activities and Therapeutic Potential
- Review, Var, NA
*AntiCan↑, *cardioP↑, *neuroP↑, *BioAv↝, *BioAv↓, *BioAv↓, *Dose↝, *Half-Life↝, *BioAv↑, *BBB↑, *hepatoP↓, *other↓, *Inflam↓, *NF-kB↓, *AP-1↓, *iNOS↓, *COX2/PTGS2↓, *ROS↓, *RNS↓, *IL8↓, *JAK↓, *PDGFR-BB↓, *IGF-1R↓, *MMP2↓, *P53↓, *NRF2↑, *TNF-α↓, *IL6↓, *E2Fs↑, *SOD1↑, *SOD2↑, Casp3↑, Cyt‑c↑, PARP↑, DNMTs↓, Telomerase↓, Hif1a↓, MMPs↓, BAX↑, Bak↑, Bcl-2↓, Bcl-xL↓, P53↑, PTEN↑, TumCP↓, MAPK↓, HGF/c-Met↓, TIMP1↑, HDAC↓, MMP9↓, uPA↓, GlutMet↓, ChemoSen↑, chemoP↑,
3593- EGCG,    Epigallocatechin Gallate (EGCG)
- Review, AD, NA
AntiTum↑, *Inflam↓, *neuroP↑, *Aβ↓, *BioAv↝, cognitive↑,
6780- EGCG,    The pharmacological activity of epigallocatechin-3-gallate (EGCG) on Alzheimer's disease animal model: A systematic review
- Review, AD, NA
*neuroP↑, *tau↓, *antiOx↑, *Inflam↓, *Apoptosis↓, *AChE↓, *TNF-α↓, *JNK↓, *NGF↑, *SOD↑, *GPx↑, *MDA↓, *NO↓, *ROS↓, *iNOS↓, *COX2/PTGS2↓, *BAX↓, *CHOP/DDIT3↓, *GRP78/BiP↓, *Bcl-2↑, *Dose↑, *BioAv↑, *hepatoP↓,
6779- EGCG,    Effectiveness of epigallocatechin gallate nanoparticles on the in-vivo treatment of Alzheimer's disease in a rat/mouse model: a systematic review
- Review, AD, NA
*BioAv↑, *ROS↓, *AChE↓, *Dose↝, *neuroP↑, *APP↓, *GSK‐3β↓, *PDK1 / PDPK1↓, *BBB↑, *memory↑,
6783- EGCG,    Absorption, metabolism, bioactivity, and biotransformation of epigallocatechin gallate
- Review, Nor, NA
*antiOx↑, *Inflam↓, *AntiCan↑, *Bacteria↓, *AntiBio↑, *BioAv↓, *GutMicro↑,
6782- EGCG,    Pharmacokinetics of tea catechins after ingestion of green tea and (-)-epigallocatechin-3-gallate by humans: formation of different metabolites and individual variability
- Human, Nor, NA
*Dose↝, BioAv↝, Half-Life↝,
6789- EGCG,    Epigallocatechin-3-gallate (EGCG) for Clinical Trials: More Pitfalls than Promises?
- Review, Var, NA
BioAv↓, Half-Life↝, Half-Life↝, BioAv↝, *BioAv↑, *BioAv↓, *BioAv↑, *BioAv↑, *Dose↝, *toxicity↝,
6785- EGCG,    Epigallocatechin-3-gallate at the nanoscale: a new strategy for cancer treatment
- Review, Var, NA
AntiCan↑, BioAv↓, CompStab↑, EPR↑, TumCG↓, *Half-Life↝, BioAv↑, eff↑, eff↑, eff↑, NF-kB↓, ROS↑, ChemoSen↑, *toxicity↝,
6784- EGCG,    Dietary (−)-Epigallocatechin Gallate (EGCG): State-of-the-Art Advances in Bioactivities, Bioavailability Enhancement Strategies, and Applications in Nutrition and Health
- Review, Nor, NA
*antiOx↑, *Inflam↓, *AntiCan↑, *cardioP↑, *neuroP↑, *GutMicro↑, *AntiBio↑, *ROS↓, *TNF-α↓, *IL6↓, TumCP↓, *LDL↓, *NO↓, *Obesity↓, *p‑tau↓, *Aβ↓, *NRF2↑, *SOD↑, *Catalase↑, *GPx↑, *NLRP3↓, *mTOR↓, TumCCA↑, NRF2↓, Apoptosis↑, SIRT1↓, miR-25-5p↓, PARP↑, Casp3↑, Casp9↑, ER Stress↑, TumAuto↑, EMT↓, TumCI↓, TumCMig↓, TGF-β↓, Smad1↓, STAT3↓, VEGF↓, angioG↓, Imm↑, EGFR↓, *GutMicro↑, *Bacteria↓, *AntiViral↑, *BioAv↓, *BioAv↑, *Synergy↑, *BioAv↑, Synergy↑, ChemoSen↑, *toxicity↝,
648- EGCG,    Bioavailability of Epigallocatechin Gallate Administered With Different Nutritional Strategies in Healthy Volunteers
- Human, Nor, NA
*BioAv↑,
647- EGCG,    Food Inhibits the Oral Bioavailability of the Major Green Tea Antioxidant Epigallocatechin Gallate in Humans
- Human, Nor, NA
*BioAv↑,
646- EGCG,  PI,    Piperine enhances the bioavailability of the tea polyphenol (-)-epigallocatechin-3-gallate in mice
- in-vivo, Nor, NA
*BioAv↑,
644- EGCG,  Citrate,    Simple Approach to Enhance Green Tea Epigallocatechin Gallate Stability in Aqueous Solutions and Bioavailability: Experimental and Theoretical Characterizations
- Analysis, Nor, NA
*BioAv↑,
675- EGCG,    When Natural Compounds Meet Nanotechnology: Nature-Inspired Nanomedicines for Cancer Immunotherapy
- Review, Var, NA
*BioAv↑,
1516- EGCG,    Epigallocatechin Gallate (EGCG): Pharmacological Properties, Biological Activities and Therapeutic Potential
- Review, Var, NA
*Dose∅, *Half-Life∅, *BioAv∅, *BBB↑, *toxicity∅, eff↓, Apoptosis↑, Casp3↑, Cyt‑c↑, cl‑PARP↑, DNMTs↓, Telomerase↓, angioG↓, Hif1a↓, NF-kB↓, MMPs↓, BAX↑, Bak↑, Bcl-2↓, Bcl-xL↓, P53↑, PTEN↑, IGF-1↓, H3↓, HDAC1↓, *LDH↓, *ROS↓,
2994- EGCG,    Nano-Engineered Epigallocatechin Gallate (EGCG) Delivery Systems: Overcoming Bioavailability Barriers to Unlock Clinical Potential in Cancer Therapy
- Review, Var, NA
BioAv↓, NF-kB↓, Casp↑, MMP9↑, Sp1/3/4↑,
6049- EGCG,  SeNPs,    Epigallocatechin-3-gallate (EGCG)-stabilized selenium nanoparticles coated with Tet-1 peptide to reduce amyloid-β aggregation and cytotoxicity
- Study, AD, PC12
*Aβ↓, *Dose↝, *BioAv↑, *ROS↓,
5227- EMD,    Emodin and emodin-rich rhubarb inhibits histone deacetylase (HDAC) activity and cardiac myocyte hypertrophy
- vitro+vivo, Nor, NA
*cardioP↑, HDAC↓, HDAC1↓, HDAC2↓, ac‑H3↑, Dose↝, BioAv↓,
6819- EMD,    Recent advances in the therapeutic potential of emodin for human health
- Review, Nor, NA
AntiCan↑, *AntiDiabetic↑, *neuroP↑, *Inflam↓, *antiOx↑, *BioAv↓, *BioAv↑, *SOD↑, *GPx↑, *GSH↑, *NRF2↑, *ROS↓, *lipid-P↓, *Cyt‑c↓, *BAX↓, *Bcl-2↓, *iNOS↓, *NO↓, *IL6↓, *IL10↓, *IL17↓, *IFN-γ↓, *NF-kB↓, *LC3II↓, *Akt↓, *Beclin-1/ATG6↓, *AMPK↓, *TNF-α↓, *PGE2↓, *Apoptosis↓, *Casp3↓, *Casp9↓, *P53↓, *P21↓, *NAD↓, *ATP↓, *CHOP/DDIT3↓, *GADD34↓, *ATF4↓, tumCV↓, Apoptosis↑, TumCG↓, TumCI↓, TumMeta↓, CSCs↓, NOTCH1↓, STAT3↓, Synergy↑, miR-34a↓, *neuroP↑, *BDNF↓, *hepatoP↑, *ALAT↓, *AST↓, TG/TAG↓, ROS↑, Slug↓, EMT↓, Glycolysis↓, ChemoSen↑, P-gp/ABCB1↓, Ki-67↓, PCNA↓, ER Stress↑, TRIB3↑, NF-kB↑, TumMeta↑, *Imm↓, *toxicity↝,
6824- EMD,    Neuroprotective, Anti-Inflammatory and Antifibrillogenic Offerings by Emodin against Alzheimer’s Dementia: A Systematic Review
- Review, AD, NA
*Inflam?, *antiOx↑, *tau↓, *Aβ↓, *neuroP↑, *ROS↓, *memory↑, *cognitive↑, *other↝, *AChE↓, *BACE/β-secretase↓, *LC3II↓, *Beclin-1/ATG6↓, *p‑tau↓, *CREB↑, *HNE↓, *BioAv↓, *BioAv↝, *BioAv↑, *BioAv↑, *BioAv↑, *BioAv↑, BioAv↑, *HO-1↑, *PKCδ↑, *Akt↑, *NLRP3↓, *NF-kB↓, *TLR3↓,
6823- EMD,    Role of emodin to prevent gastrointestinal cancers: recent trends and future prospective
- Review, Var, NA
AntiCan↑, *antiOx↑, *chemoP↑, *Inflam↓, TumCP↓, TumMeta↓, TumCCA↑, MAPK↑, BAX↑, Casp↑, ROS↑, *BioAv↓, other↝, TumCI↓, EMT↓, TumCG↑, Apoptosis↑, TumCP↑, MMP2↓, Casp3↑, ChemoSen↑, PI3K↓, Akt↓, Cyt‑c↑, cl‑PARP↑, MMP↓, Warburg↓, HK2↓, PKM2↓, LDHA↓, mtDam↑, Apoptosis↑, N-cadherin↓, Vim↓, E-cadherin↑, eff↑, eff↑, eff↑, toxicity↝, toxicity↑,
6831- EMD,  PI,    Effect of piperine on the bioavailability and pharmacokinetics of emodin in rats
- in-vivo, Nor, NA
*BioAv↑,
6836- EMD,    Emodin and the Anthraquinone Scaffold: Therapeutic Promise and Strategies to Overcome Translational Barriers
- Review, Nor, NA
*antiOx↑, *neuroP↑, *Inflam↓, *hepatoP↑, AntiTum↑, *Bacteria↓, *diuretic↑, *AntiDiabetic↑, *BioAv↝, *NF-kB↓, *AMPK↑, *JAK↓, *STAT3↓, *ROS↓, *lipid-P↓, ROS↑, TumCCA↑, CycB/CCNB1↓, BAX↑, Bcl-2↓, MOMP↑, Cyt‑c↑, Casp9↑, Casp3↑, Casp7↑, Apoptosis↑, P53↑,
6814- EMD,    Emodin: A Review of its Pharmacology, Toxicity and Pharmacokinetics
- Review, Nor, NA
AntiCan↑, *hepatoP↑, *Inflam↑, *antiOx↑, *AntiBio↑, *BioAv↓, *AntiViral↑, *AntiDiabetic↑, *neuroP↑, CSCs↓, NOTCH↓, β-catenin/ZEB1↓, STAT3↓, TumCCA↑, *TNF-α↓, IL6↓, IL1β↓, *MMP9↓, *HO-1↑, cMyc↓, Mcl-1↓, *antiAll↑,
1324- EMD,    Is Emodin with Anticancer Effects Completely Innocent? Two Sides of the Coin
- Review, Var, NA
*toxicity↑, *BioAv↓, Akt↓, ERK↓, ROS↑, MMP↓, Bcl-2↓, BAX↑, TumCCA↑,
5256- EP,    Pulsed electric fields: a sharp sword in the battle against cancers
- Review, Var, NA
BioAv↑, TumCD↑, MMP↓, Apoptosis↑, TumCCA↑, Imm↑, RadioS↑, ChemoSen↑,
6581- EU,    Bioavailability of Eurycomanone in Its Pure Form and in a Standardised Eurycoma longifolia Water Extract
- in-vitro, Colon, Caco-2 - in-vivo, Nor, NA
*Half-Life↓, *BioAv↝,
6383- Eug,    In Vitro Incorporation of Radioiodinated Eugenol on Adenocarcinoma Cell Lines (Caco2, MCF7, and PC3)
- in-vitro, Colon, Caco-2 - in-vitro, BC, MCF7 - in-vitro, Pca, PC3
antiOx↑, Inflam↓, AntiCan↓, other↝, BioAv↑, other↝,
6381- Eug,    Biological Properties and Prospects for the Application of Eugenol—A Review
- Review, Var, NA
*eff↑, *BioAv↝, *CompStab↝, *BioAv↑, *antiOx↑, *AntiAg↑, *Inflam↓, *AntiBio↑, *MAOA↓, *neuroP↑, *ROS↓, *RNS↓, *Synergy↑, NF-kB↓, PGE2↓, COX2/PTGS2↓, TumCCA↑, Apoptosis↑, TumCMig↓, TumCI↓, tumCV↓, PI3K↓, Akt↓, MMPs↓, ChemoSen↑, ALDH↓, *Pain↓, *VGSC↓, *IL1β↓, *IL6↓, *TNF-α↓, *iNOS↓, *5LO↓, *chemoPv↑, *antiAll↑,
6389- Eug,    Molecular Insights into the Management of Eugenol's Anticancer Action Against Colon Cancer: A Detailed Review
- Review, Colon, NA
Apoptosis↓, TumCCA↓, Inflam↓, TumMeta↓, BioAv↑, eff↓, Half-Life↓, *ROS↓, *RNS↓, *SOD↓, *Catalase↑, *GSTs↑, *MAOA↓, *neuroP↑, *DNAdam↓, Apoptosis↑, ROS↑, selectivity↑, MMP↓, Cyt‑c↓, Casp3↑, Casp9↑, TumCD↑, BAX↑, BAD↑, APAF1↑, Bcl-2↓, Bcl-xL↓, P53↑, cl‑PARP↑, TumCCA↑, cycD1/CCND1↓, CycB/CCNB1↓, CDK2↓, CDK4↓, P21↑, p27/CDKN1B↑, NF-kB↓, COX2/PTGS2↓, PGE2↓, MAPK↓, PI3K↓, Akt↓, mTOR↓, MMPs↓, EMT↓, Snail↓, Slug↓, Zeb1↓, E-cadherin↑, ChemoSen↑, CompStab↑,
6388- Eug,    Eugenol’s anti-cancer properties, its modulation of signalling pathways, and cascades across various cancers: A review
- Review, Var, NA
Dose↝, AntiCan↑, *Inflam↓, *cardioP↑, *neuroP↑, angioG↓, TumMeta↓, *BioAv↑, *CompStab↑, *toxicity↝, antiNeop↑, TumCCA↑, Apoptosis↑, *antiOx↑, *lipid-P↓, *ROS↓, *SOD↑, *Catalase↑, *GSTs↑, *GPx↑, *iNOS↓, *COX2/PTGS2↓, *IL6↓, *TNF-α↓, *AntiArt↑, *Bacteria↓, TumAuto↑, PI3K↓, Akt↓, FOXO3↝, BAX↑, mTOR↓, NF-kB↓, P53↑, TumCG↓, CSCs↓, CD44↓, EpCAM↓, NOTCH1↓, OCT4↓, Bcl-2↓, PDK1 / PDPK1↓, HER2/EBBR2↓, BAD↓, cycD1/CCND1↓, ROS↑, Casp3↑, selectivity↑, MMP2↓, MMP9↓, TIMP1↑, VEGF↓, VEGFR1↓, RECK↑, TIMP2↑, DNAdam↑, MMP↓, Thiols↓, PARP↑, *Pain↓, E2Fs↓, survivin↓,
6325- Eug,    Anticancer Properties of Eugenol: A Review
- Review, Var, NA
*antiOx↑, *AntiCan↑, *Inflam↓, TumCD↑, TumCCA↑, TumCMig↓, TumMeta↓, angioG↓, ChemoSen↑, chemoP↑, *BioAv↝, *BioAv↑, *BioAv↑, *BioAv↑, *Bacteria↓, *ROS↓, *IL6↓, *COX2/PTGS2↓, *TNF-α↓, *lipid-P↓, *SOD1↑, *Catalase↑, *GPx1↑, *GSTs↑, ROS↑, MMP↓, Apoptosis↑, COX2/PTGS2↓, TumCCA↑, E2Fs↓, PI3K↓, Akt↓, MMPs↓, CSCs↓, OCT4↓, CD44↓, EpCAM↓, NOTCH1↓, TumVol↓, Casp3↑, P53↑, cl‑PARP↑, MMP2↓, MMP9↓, TIMP1↑, ALDH↓, NF-kB↓, *toxicity↓,
6323- Eug,    Eugenol: An Insight Into the Anticancer Perspective and Pharmacological Aspects
- Review, Var, NA - Review, Arthritis, NA
*AntiCan↑, *AntiDiabetic↑, *cardioP↑, *toxicity↝, *GutMicro↑, *neuroP↑, *BioAv⇅, *BioAv↝, *antiOx↑, *Inflam↑, *AntiArt↑, *TNF-α↓, *IL6↓, *IL10↓, *GSH↑, *GPx↑, *Catalase↑, *MDA↓, *TAC↑, TumCMig↓, TumCI↓, Akt↑, FOXO3↑, Casp3↑, Casp9↑, P21↑, angioG↓, TumCI↓, Apoptosis↑, NF-kB↓, Synergy↑, Synergy↑, ChemoSen↑, NA↑, Casp3↑, Casp9↑, *AntiDiabetic↑, *glucose↓, *ROS↓, *Inflam↓, *MDA↓, *GSH↑, *BioAv↑,
6847- EVO,    Evodiamine as an anticancer agent: a comprehensive review on its therapeutic application, pharmacokinetic, toxicity, and metabolism in various cancers
- Review, Var, NA
ChemoSen↑, BioAv↝,
6848- EVO,    Evodiamine: A Extremely Potential Drug Development Candidate of Alkaloids from Evodia rutaecarpa
- Review, Nor, NA
AntiTum↑, cardioP↑, Inflam↓, TumCP↓, TumCCA↑, Apoptosis↑, TumAuto↑, BioAv↓, toxicity↑, NF-kB↓, MAPK↓, NOD1↓, p‑Akt↓, BAX↑, cl‑Casp3↑, γH2AX↑, cl‑PARP↑, ROS↑, BBB↑, neuroP↑, BioAv↑,
6868- FA,    Examination of the Bioavailability and Bioconversion of Wheat Bran-Bound Ferulic Acid: Insights into Gastrointestinal Processing and Colonic Metabolites
- in-vivo, Nor, NA
*BioAv↓,
6871- FA,  Sesame,    Nano-encapsulated ferulic acid in sesame protein isolate alleviates acrylamide-induced liver toxicity and genotoxicity in rats via oxidative stress and DNA damage modulation
- in-vivo, Nor, NA
*GSH↑, *GPx↑, *SOD↓, *Catalase↑, *MDA↓, *IL6↓, *TNF-α↑, *DNAdam↓, *hepatoP↑, *BioAv↓, *BioAv↑, CompStab↓,
6881- FA,    Potential Therapeutic Efficacy of Ferulic Acid and Its Derivatives in the Management of Cancers: A Comprehensive Analysis With Mechanistic Insight
- Review, Var, NA
ROS↑, TumCCA↑, TumCI↓, TumCMig↓, TumCP↓, BioAv↑, BioAv↑, TP53↑, CDK2↓, CDK4↓, CDK6↓, JAK2↓, STAT6↓, tyrosinase↓, p‑Akt↓, p‑PI3K↓, mTOR↓, Ki-67↓, Casp3↑, proCasp8↑, cl‑PARP↑, BAX↑, Bcl-2↓, Mcl-1↓, MMP9↓, cycD1/CCND1↓, cycE/CCNE↓, PINK1↑, PARK2↑, MMP↓, CycD3↓, TumAuto⇅, Synergy↑, Synergy↑, ALAT↓, AST↓, ALP↓, VEGF↓, MMPs↓, angioG↓,
1654- FA,    Molecular mechanism of ferulic acid and its derivatives in tumor progression
- Review, Var, NA
AntiCan↑, Inflam↓, RadioS↑, ROS↑, Apoptosis↑, TumCCA↑, TumCMig↑, TumCI↓, angioG↓, ChemoSen↑, ChemoSideEff↓, P53↑, cycD1/CCND1↓, CDK4↓, CDK6↓, TumW↓, miR-34a↑, Bcl-2↓, Casp3↑, BAX↑, β-catenin/ZEB1↓, cMyc↓, Bax:Bcl2↑, SOD↓, GSH↓, LDH↓, ERK↑, Synergy↑, JAK2↓, STAT6↓, NF-kB↓, PYCR1↓, PI3K↓, Akt↓, mTOR↓, Ki-67↓, VEGF↓, FGFR1↓, EMT↓, CAIX/CA9↓, LC3II↑, p62↑, PKM2↓, Glycolysis↓, *BioAv↓,
1656- FA,    Ferulic Acid: A Natural Phenol That Inhibits Neoplastic Events through Modulation of Oncogenic Signaling
- Review, Var, NA
tyrosinase↓, CK2↓, TumCP↓, TumCMig↓, FGF↓, FGFR1↓, PI3K↓, Akt↓, VEGF↓, FGFR1↓, FGFR2↓, PDGF↓, ALAT↓, AST↓, TumCCA↑, CDK2↓, CDK4↓, CDK6↓, BAX↓, Bcl-2↓, MMP2↓, MMP9↓, P53↑, PARP↑, PUMA↑, NOXA↑, Casp3↑, Casp9↑, TIMP1↑, lipid-P↑, mtDam↑, EMT↓, Vim↓, E-cadherin↓, p‑STAT3↓, COX2/PTGS2↓, CDC25↓, RadioS↑, ROS↑, DNAdam↑, γH2AX↑, PTEN↑, LC3II↓, Beclin-1/ATG6↓, SOD↓, Catalase↓, GPx↓, Fas↑, *BioAv↓, cMyc↓, Beclin-1/ATG6↑, LC3‑Ⅱ/LC3‑Ⅰ↓,
7829- FA,  MBS,    Neuroprotective Potential of Mung Bean (Vigna radiata L.) Polyphenols in Alzheimer's Disease: A Review
- Review, AD, NA
*BioAv↑, *cognitive↓, *Dose↝, *neuroP↑, *Aβ↓, *BACE/β-secretase↓, *ADAM10↑, *Ac-histone H3↑, *BloodF↑, *IRes↑, *memory↑, *Dose↝,
4069- FA,    Folate, folic acid and 5-methyltetrahydrofolate are not the same thing
- Review, AD, NA
*other↑, *BioAv↝, *other↝, *eff↑,
3712- FA,    Ferulic Acid: A Hope for Alzheimer’s Disease Therapy from Plants
- Review, AD, NA
*antiOx↑, *Inflam↓, *ROS↓, *Aβ↓, *HO-1↑, *HSP70/HSPA5↑, *ERK↑, *Akt↑, *iNOS↓, *COX2/PTGS2↓, *cardioP↑, *memory↑, *IL2↓, *cognitive↑, *APP↓, *SOD↑, *Catalase↑, *Akt↑, *BioAv↑,

Showing Research Papers: 351 to 400 of 856
Prev Page 8 of 18 Next

* indicates research on normal cells as opposed to diseased cells
Total Research Paper Matches: 856

Pathway results for Effect on Cancer / Diseased Cells:


NA, unassigned(tgid=0) ⓘ

NA↑, 5,  

Redox & Oxidative Stress(tgid=1) ⓘ

antiOx↓, 4,   antiOx↑, 17,   ARE↓, 1,   Catalase↓, 7,   Catalase↑, 5,   Fenton↑, 4,   frataxin↑, 1,   GPx↓, 3,   GPx↑, 5,   GPx4↓, 11,   GPx4↑, 1,   GSH↓, 34,   GSH↑, 7,   GSH/GSSG↓, 1,   GSR↓, 2,   GSR↑, 1,   ox-GSSG↑, 1,   GSTs↓, 1,   GSTs↑, 2,   H2O2↓, 1,   H2O2↑, 4,   e-H2O2↓, 1,   i-H2O2∅, 1,   HO-1↓, 6,   HO-1↑, 10,   HO-2↓, 1,   Iron↑, 5,   Iron↝, 1,   i-Iron↑, 1,   c-Iron↑, 1,   Keap1↓, 1,   Keap1↑, 1,   lipid-P?, 1,   lipid-P↓, 8,   lipid-P↑, 15,   MDA↓, 3,   MDA↑, 5,   NADH↓, 1,   NOX↓, 1,   NOX4↓, 1,   NOX4↑, 1,   NQO1↓, 1,   NQO1↑, 3,   NRF2↓, 16,   NRF2↑, 23,   Prx↓, 1,   Prx4↑, 1,   Prx6↑, 1,   ox-PrxI↑, 1,   PrxII↓, 1,   PYCR1↓, 1,   ROS?, 1,   ROS↓, 28,   ROS↑, 235,   ROS⇅, 9,   ROS↝, 3,   i-ROS↓, 1,   i-ROS↑, 2,   mt-ROS↑, 1,   SOD↓, 9,   SOD↑, 8,   SOD1↓, 2,   SOD2↓, 4,   SOD2↑, 1,   Thiols↓, 2,   Trx↓, 2,   Trx1↑, 1,   TrxR↓, 8,   VitC↓, 1,   VitE↓, 1,   xCT/SLC7A11↓, 2,  

Metal & Cofactor Biology(tgid=2) ⓘ

Ferritin↓, 1,   IronCh↑, 5,   Tf↓, 1,   Tf↑, 1,   TfR1/CD71↑, 2,   Zn2+↑, 1,  

Mitochondria & Bioenergetics(tgid=3) ⓘ

ADP:ATP↑, 2,   BCR-ABL↓, 1,   CDC2↓, 4,   CDC25↓, 5,   compI↓, 6,   compII↓, 1,   compIII↓, 1,   compV↓, 1,   EGF↓, 2,   ETC↓, 3,   ETC↑, 1,   MFN2↑, 1,   mitResp↓, 2,   Mortalin↓, 1,   mtDam↓, 1,   mtDam↑, 15,   OCR↓, 2,   OCR↑, 3,   OXPHOS↓, 5,   OXPHOS↑, 3,   mt-OXPHOS↓, 2,   PDH↑, 2,   PGC-1α↑, 1,   PINK1↑, 1,   SDH↑, 1,   SIRT3↓, 1,   SIRT3↑, 1,  

Core Metabolism/Glycolysis(tgid=4) ⓘ

12LOX?, 1,   12LOX↓, 1,   5LO↓, 5,   ACLY↓, 2,   ACSL4↑, 1,   ALAT↓, 6,   ALAT↑, 1,   ALDOA↓, 1,   AMPK↑, 19,   AMPK↝, 1,   p‑AMT/GCST/T-protein↑, 1,   ATP↓, 18,   ATP↑, 1,   mt-ATP↓, 1,   CAIX/CA9↓, 1,   CAIX/CA9↑, 1,   CRM↝, 1,   ECAR↓, 3,   ECAR↝, 1,   ENO1↓, 2,   FASN↓, 5,   FDG↓, 1,   GAPDH↓, 2,   GLO-I↓, 1,   glucoNG↓, 1,   glucose↓, 1,   GlucoseCon↓, 12,   GlutaM↓, 1,   GlutMet↓, 1,   Glycolysis↓, 36,   Glycolysis↝, 1,   GSK‐3β↓, 14,   GSK‐3β↑, 5,   p‑GSK‐3β↓, 1,   H2S↑, 1,   HK1↓, 1,   HK2↓, 18,   HMG-CoA↓, 1,   IDH1↓, 1,   lactateProd↓, 14,   lactateProd↑, 1,   LDHA↓, 3,   LDL↓, 4,   lipoGen↓, 1,   MCT4↓, 2,   NADH:NAD↓, 1,   NADPH↓, 4,   PDK1 / PDPK1?, 2,   PDK1 / PDPK1↓, 8,   PDK3↑, 1,   PFK1↓, 1,   PKM2↓, 11,   SCD1↓, 1,   SIRT1↓, 8,   SIRT1↑, 8,   SIRT2↓, 1,   SIRT2↑, 1,   SREBP1/SREBF1↓, 1,   TCA↓, 2,   TCA↑, 1,   TCA↝, 1,   UGDH↓, 2,   Warburg↓, 11,  

Cell Death(tgid=5) ⓘ

AIF↑, 13,   APAF1↑, 4,   Apoptosis?, 1,   Apoptosis↓, 2,   Apoptosis↑, 190,   mt-Apoptosis↑, 2,   ASC↓, 1,   BAD↓, 2,   BAD↑, 4,   Bak↓, 1,   Bak↑, 6,   BAX↓, 3,   BAX↑, 84,   Bax:Bcl2↓, 1,   Bax:Bcl2↑, 20,   Bcl-2↓, 85,   Bcl-2↑, 4,   Bcl-xL↓, 20,   BID↓, 1,   BID↑, 3,   p‑BID↓, 1,   BIM↓, 1,   BIM↑, 4,   BNIP3↑, 1,   BNIP3↝, 1,   BOK↑, 1,   Casp↑, 39,   cl‑Casp↑, 1,   Casp1↓, 1,   Casp1↑, 3,   Casp12?, 1,   Casp12↑, 1,   cl‑Casp12↑, 1,   Casp3↓, 2,   Casp3↑, 101,   Casp3↝, 1,   cl‑Casp3↑, 13,   cl‑Casp3⇅, 1,   proCasp3↑, 1,   Casp6↑, 1,   Casp7↑, 14,   cl‑Casp7↑, 2,   Casp8↑, 23,   cl‑Casp8↑, 2,   proCasp8↑, 1,   pro‑Casp8↑, 1,   Casp9↓, 1,   Casp9↑, 61,   cl‑Casp9↑, 6,   proCasp9↓, 1,   cFLIP↓, 3,   Cyt‑c↓, 3,   Cyt‑c↑, 56,   Cyt‑c↝, 1,   Diablo↑, 3,   DR5↑, 19,   Endon↑, 1,   FADD↑, 5,   Fas↑, 11,   FasL↓, 1,   FasL↑, 6,   Ferroptosis↑, 20,   GranB/GZMB↓, 1,   GranB/GZMB↝, 1,   GSDME↑, 1,   IAP1↓, 4,   IAP2/BIRC3↓, 2,   IAP2/BIRC3↑, 1,   ICD↑, 1,   iNOS↓, 15,   Mcl-1↓, 18,   Mcl-1↑, 1,   p‑Mcl-1↓, 1,   MDM2↓, 8,   MDM2↑, 2,   p‑MDM2↓, 1,   MOMP↓, 1,   MOMP↑, 4,   NAIP↓, 1,   Necroptosis↑, 2,   necrosis↑, 4,   NOXA↑, 4,   p38↓, 2,   p38↑, 14,   p‑p38↓, 1,   p‑p38↑, 2,   Paraptosis↑, 1,   Perforin↝, 1,   pS2/TFF1↓, 1,   PUMA↓, 1,   PUMA↑, 5,   Pyro↑, 3,   RIP1↑, 1,   RIP3↑, 1,   survivin↓, 37,   TRAIL↑, 2,   TRAIL⇅, 1,   TRAILR↑, 1,   TumCD↓, 2,   TumCD↑, 17,   XIAP↓, 20,   XIAP↑, 1,   YAP/TEAD↓, 4,  

Kinase & Signal Transduction(tgid=6) ⓘ

ABL1↓, 2,   Akt↓, 126,   Akt↑, 6,   p‑Akt↓, 31,   AKT1↓, 3,   Akt2↓, 1,   AMPKα↑, 1,   BRAF↓, 1,   CaMKII ↓, 1,   CIP2A↓, 1,   CK2↓, 2,   cMET↓, 3,   cSrc↓, 2,   DDIT4↑, 1,   DYRK1B↓, 1,   EF-1α↓, 1,   EGFR↓, 30,   EGFR↑, 2,   p‑EGFR↓, 1,   ERK↓, 42,   ERK↑, 5,   p‑ERK↓, 12,   FGFR1↓, 3,   FGFR2↓, 1,   FOXD3↑, 1,   HER2/EBBR2↓, 7,   HGF/c-Met↓, 3,   Hippo↑, 1,   IGF-1R↓, 3,   IGF-2R↑, 1,   IKKα↓, 3,   p‑IKKα↓, 1,   IκB↓, 1,   IκB↑, 1,   JAK↓, 5,   JAK1↓, 3,   JAK1↑, 1,   JAK2↓, 9,   p‑JAK2↓, 1,   JNK↓, 6,   JNK↑, 16,   p‑JNK↑, 2,   LIMK1↓, 1,   p‑MAP2K1/MEK1↓, 1,   MAPK↓, 32,   MAPK↑, 13,   MAPK↝, 2,   p‑MAPK↓, 1,   MARK4↓, 2,   MEK↓, 3,   mTOR↓, 70,   mTOR⇅, 1,   mTOR↝, 2,   p‑mTOR↓, 6,   p‑p70S6↓, 1,   P70S6K↓, 2,   p‑P70S6K↓, 1,   p‑PDGFR-BB↓, 1,   PI3K↓, 98,   PI3K↑, 3,   PI3K↝, 1,   p‑PI3K↓, 4,   p‑PI3K↑, 1,   PKA↓, 2,   PKCδ↓, 7,   PP2A↑, 1,   PTEN↓, 2,   PTEN↑, 33,   Raf↓, 3,   c-Raf↓, 1,   RAS↓, 11,   RET↓, 1,   SHP1↑, 1,   Sp1/3/4↓, 6,   Sp1/3/4↑, 1,   Src↓, 3,   p‑Src↓, 1,   STAT↓, 3,   STAT3↓, 65,   STAT3↑, 3,   p‑STAT3↓, 10,   p‑STAT3↑, 2,   STAT6↓, 3,   p‑STAT6↓, 1,  

Transcription & Epigenetics(tgid=7) ⓘ

ATF3↓, 1,   ATF4↑, 6,   ATF4↝, 1,   CBP↓, 2,   cJun↓, 3,   cJun↑, 1,   p‑cJun↑, 1,   cMyc↓, 34,   cMyc↑, 1,   p‑cMyc↑, 1,   DNMT1↓, 7,   DNMT3A↓, 2,   DNMTs↓, 7,   EZH2↓, 5,   FOXM1↓, 4,   FOXO1↓, 2,   FOXO1↑, 2,   FOXO3↓, 1,   FOXO3↑, 4,   FOXO3↝, 1,   FOXO4↑, 2,   H3↓, 2,   H3↑, 2,   ac‑H3↑, 1,   H4↓, 1,   H4↑, 2,   HATs↓, 4,   HATs↑, 4,   HDAC↓, 27,   HDAC1↓, 8,   HDAC10↓, 1,   HDAC2↓, 6,   HDAC3↓, 2,   HDAC4↓, 1,   HDAC8↓, 2,   HES1↓, 1,   miR-106b↓, 2,   miR-107↑, 1,   miR-124-3p↓, 1,   miR-139-5p↑, 1,   miR-155↓, 2,   miR-19b↓, 2,   miR-200b↑, 1,   miR-203↑, 1,   miR-21↓, 7,   miR-218↑, 1,   miR-224↓, 1,   miR-25-5p↓, 1,   miR-27a-3p↓, 1,   miR-29b↓, 1,   miR-30a-5p↑, 1,   miR-339-5p↝, 1,   miR-340↓, 1,   miR-34a↓, 2,   miR-34a↑, 6,   miR-375↑, 1,   miR-384↑, 1,   miR-422a↑, 1,   miR-590-3p↑, 1,   MTA2↓, 1,   Myc↓, 5,   MYCN↓, 1,   OCT4↓, 9,   other↓, 2,   other↑, 8,   other↝, 40,   other∅, 1,   PhotoS↑, 3,   SD↑, 1,   sonoS↑, 1,   SOX2↓, 6,   SOX4↓, 2,   SOX4↑, 1,   SOX9?, 1,   tumCV?, 1,   tumCV↓, 24,   ZBTB10↑, 1,  

Protein Folding & ER Stress(tgid=8) ⓘ

ATF6↑, 1,   CHOP/DDIT3↓, 1,   CHOP/DDIT3↑, 15,   cl‑CHOP/DDIT3↑, 1,   CUL1↝, 1,   CUL5↝, 1,   eIF2α↓, 1,   eIF2α↑, 4,   p‑eIF2α↑, 2,   ER Stress↓, 1,   ER Stress↑, 34,   GRP78/BiP?, 1,   GRP78/BiP↓, 2,   GRP78/BiP↑, 6,   GRP78/BiP↝, 1,   HSP27↝, 1,   HSP70/HSPA5↓, 2,   HSP70/HSPA5↑, 1,   HSP70/HSPA5↝, 1,   HSP90↓, 12,   PERK↑, 8,   Proteasome↓, 1,   UPR↑, 6,   XBP-1↓, 1,   XBP-1↑, 1,  

Autophagy & Lysosomes(tgid=9) ⓘ

ATG5↑, 2,   ATG7↑, 2,   Beclin-1/ATG6↓, 1,   Beclin-1/ATG6↑, 8,   CTSK↓, 1,   LAMP1?, 1,   LC3‑Ⅱ/LC3‑Ⅰ↓, 1,   LC3‑Ⅱ/LC3‑Ⅰ↑, 1,   LC3B-II↑, 2,   LC3II↓, 2,   LC3II↑, 14,   p62↓, 5,   p62↑, 3,   PARK2↑, 1,   SESN2↑, 2,   TFEB↑, 1,   TumAuto↓, 2,   TumAuto↑, 38,   TumAuto⇅, 1,   TumAuto↝, 2,  

DNA Damage & Repair(tgid=10) ⓘ

APE1/APEX1↓, 1,   ATM?, 1,   ATM↑, 2,   BRCA1↓, 2,   p‑BRCA1↑, 1,   DFF45↓, 1,   DNAdam↓, 3,   DNAdam↑, 51,   DNAdamC↑, 1,   DNArepair↓, 3,   DNArepair↑, 1,   ERCC3↑, 1,   m-FAM72A↓, 1,   G9a↓, 1,   hTERT/TERT↓, 13,   MGMT↓, 2,   NKX3.1↓, 1,   p16↑, 2,   P53?, 1,   P53↓, 4,   P53↑, 72,   p‑P53↑, 1,   p53 Wildtype↓, 1,   p53 Wildtype↑, 1,   p53 Wildtype∅, 1,   p73↑, 1,   PARP↓, 1,   PARP↑, 19,   cl‑PARP↓, 2,   cl‑PARP↑, 49,   PARP1↑, 1,   PCNA↓, 17,   SIRT6↑, 1,   Telomerase↓, 16,   TOP1?, 1,   TOP1↓, 11,   TOP2↓, 6,   TOP2↑, 2,   TP53↑, 4,   UHRF1↓, 1,   XRCC1↓, 1,   γH2AX↓, 1,   γH2AX↑, 3,   γH2AX↝, 1,  

Cell Cycle & Senescence(tgid=11) ⓘ

CC(CDKs/cyclins)↓, 1,   CDK1↓, 8,   CDK1↑, 5,   CDK2↓, 30,   CDK2↑, 1,   CDK4↓, 39,   p‑CDK4↓, 1,   CDK4/6↓, 1,   CDK6↓, 11,   CDK6↑, 1,   CDK7↓, 1,   CDK8↓, 1,   CDKN1C/p57↓, 1,   CDKN1C/p57↑, 1,   CHK1↓, 2,   p‑CHK1↑, 1,   Chk2↓, 2,   Cyc↓, 1,   cycA1/CCNA1↓, 3,   cycA1/CCNA1↑, 2,   CycB/CCNB1↓, 21,   CycB/CCNB1↑, 4,   cycD1/CCND1↓, 54,   cycD1/CCND1↑, 2,   p‑cycD1/CCND1↓, 1,   CycD3↓, 1,   cycE/CCNE↓, 13,   E2Fs↓, 5,   E2Fs↑, 1,   Ki-67↓, 27,   mitA↑, 3,   p19↑, 1,   P21?, 1,   P21↓, 1,   P21↑, 42,   p27/CDKN1B↓, 2,   p27/CDKN1B↑, 16,   pRB↓, 1,   RB1↑, 1,   p‑RB1↓, 5,   Securin↓, 1,   TubPol↓, 1,   TumCCA↓, 6,   TumCCA↑, 169,   UBE2C↓, 1,  

Proliferation, Differentiation & Cell State(tgid=12) ⓘ

ALDH↓, 7,   ALDH1A1↓, 2,   ALDH1A3↓, 1,   Axin2↑, 1,   BMP7/OP1↓, 1,   BMPs↑, 2,   CD133↓, 3,   CD133↑, 1,   CD34↓, 1,   cFos↓, 4,   cFos↑, 1,   cMYB↓, 2,   CSCs?, 1,   CSCs↓, 43,   Diff↑, 2,   EIF4E↓, 1,   FGF↓, 3,   Gli↓, 2,   Gli1↓, 9,   HH↓, 10,   HH∅, 1,   HMGCR↓, 1,   IGF-1↓, 6,   IGFBP1↑, 1,   IGFBP3↑, 1,   JAG1↓, 1,   Ki-67↓, 27,   Let-7↑, 3,   LRP6↓, 1,   mTORC1↓, 5,   Nanog↓, 10,   Nestin↓, 2,   NICD↓, 1,   NOTCH↓, 16,   NOTCH1↓, 12,   NOTCH1↑, 4,   NOTCH3↓, 2,   p300↓, 2,   PTCH1↓, 1,   PTCH2↓, 1,   Shh↓, 8,   Smo↓, 3,   STAT1↓, 1,   TAZ↓, 1,   TumCG↓, 70,   TumCG↑, 3,   TumCP?, 1,   TumCP↓, 130,   TumCP↑, 5,   TumCP⇅, 1,   tyrosinase↓, 2,   Wnt↓, 41,   Wnt↝, 1,   Wnt/(β-catenin)↓, 2,   Zn2+↑, 1,  

Migration(tgid=13) ⓘ

AEG1↓, 1,   annexin II↓, 1,   AP-1↓, 10,   ASAP2↓, 1,   AXL↓, 1,   BACH1↓, 1,   CA↓, 1,   Ca+2↓, 3,   Ca+2↑, 18,   Ca+2↝, 2,   Cav1↓, 1,   Cdc42↓, 1,   Cdc42↑, 1,   CTNNB1↓, 1,   E-cadherin↓, 9,   E-cadherin↑, 30,   EMT↓, 64,   EMT↑, 1,   EpCAM↓, 2,   FAK↓, 11,   FAK↑, 1,   p‑FAK↓, 4,   fascin↓, 1,   Fibronectin↓, 1,   GLI2↓, 1,   hnRNPA1↓, 1,   ITGB1↓, 3,   ITGB3↓, 1,   ITGB6↓, 1,   KRAS↓, 2,   LAMs↓, 2,   MALAT1↓, 3,   MET↓, 1,   p‑MET↓, 1,   MMP-10↓, 1,   MMP1↓, 5,   MMP13↓, 4,   MMP15↓, 1,   MMP16↓, 1,   MMP2↓, 77,   MMP2↑, 1,   MMP3↓, 7,   MMP7↓, 9,   MMP9↓, 90,   MMP9↑, 4,   MMPs↓, 35,   MUC4↓, 2,   N-cadherin↓, 20,   PDGF↓, 5,   Rac1↓, 2,   RECK↑, 1,   Rho↓, 4,   Rho↑, 1,   ROCK1↓, 5,   ROCK1↑, 1,   Slug↓, 7,   Smad1↓, 1,   SMAD3↓, 1,   Snail↓, 12,   TET1?, 1,   TET1↑, 5,   TGF-β↓, 10,   TIMP1↓, 1,   TIMP1↑, 13,   TIMP2↑, 11,   TIMP3↑, 1,   TRIB3↑, 3,   TSC1↑, 1,   TumCA↓, 4,   TumCI↓, 69,   TumCMig↓, 55,   TumCMig↑, 1,   TumMeta?, 1,   TumMeta↓, 86,   TumMeta↑, 7,   TumPF↓, 1,   Twist↓, 14,   TXNIP↑, 1,   Tyro3↓, 1,   uPA↓, 14,   uPAR↓, 1,   Vim↓, 25,   Vim↑, 1,   Zeb1↓, 9,   ZEB2↓, 2,   α-SMA↓, 2,   α-SMA↑, 1,   α-tubulin↓, 1,   β-catenin/ZEB1↓, 44,   β-catenin/ZEB1↑, 2,  

Angiogenesis & Vasculature(tgid=14) ⓘ

angioG↓, 117,   angioG↑, 2,   CD31/PECAM-1↓, 6,   EGR1↑, 1,   EGR4↓, 1,   Endoglin↑, 2,   HIF-1↓, 7,   Hif1a↓, 62,   Hif1a↝, 1,   LOX1↓, 2,   NO↓, 4,   NO↑, 1,   PGI2↓, 1,   VCAM-1↓, 3,   VEGF↓, 100,   VEGF↑, 1,   VEGFR1↓, 3,   VEGFR2/KDR/Flk1↓, 8,  

Barriers & Transport(tgid=15) ⓘ

BBB↑, 16,   CLDN1↓, 4,   CLDN1↑, 1,   CX43/GJA1↓, 1,   EPR↑, 16,   GLUT1↓, 8,   GLUT1↑, 1,   GLUT3↑, 1,   GLUT4↓, 2,   IBI↑, 1,   MMP↓, 80,   MMP↑, 2,   MPT↑, 6,   NHE1↓, 2,   OATPs↓, 2,   OCLN↑, 1,   TJ↓, 1,   TJ↑, 1,   TRPV1↑, 3,   ZO-1↑, 2,  

Immune & Inflammatory Signaling(tgid=16) ⓘ

CB2 / CNR2↑, 3,   CD4+↓, 1,   CD4+↑, 1,   CD44↓, 9,   CD47↓, 1,   CD8+↑, 2,   p‑cDC2↓, 1,   COX1↓, 2,   COX1↑, 1,   COX2/PTGS2↓, 71,   COX2/PTGS2↑, 5,   CXCL12↓, 1,   CXCR4↓, 9,   Dectin1↝, 1,   DR4↑, 5,   FOXP3↓, 2,   FOXP3↑, 1,   Gal-3↓, 1,   GM-CSF↓, 1,   HCAR1↓, 1,   HLA↑, 1,   HLA-I/II↑, 1,   HMGB1↓, 2,   ICAM-1↓, 5,   IFN-γ↓, 1,   IFN-γ↑, 3,   Igs↑, 2,   IL-1Ra↑, 1,   IL1↓, 6,   IL1↑, 1,   IL10↓, 4,   IL10↑, 3,   IL12↓, 1,   IL12↑, 1,   IL18↑, 1,   IL1R2↑, 1,   IL1RL1/ST2↑, 1,   IL1α↓, 1,   IL1β↓, 20,   IL1β↑, 1,   IL2↓, 4,   IL2↑, 7,   IL4↑, 1,   IL6↓, 38,   IL8↓, 10,   Imm↑, 18,   Imm↝, 2,   INF-γ↓, 1,   Inflam↓, 42,   IRAK1↓, 1,   LRIG1↑, 1,   M2 MC↓, 1,   MCP1/CCL2↓, 3,   MCT1↓, 2,   MDSCs↓, 1,   MIP‑1α/CCL3↓, 1,   MIP2↓, 1,   mPGES-1↓, 1,   NAF1↓, 1,   NF-kB?, 1,   NF-kB↓, 141,   NF-kB↑, 4,   p‑NF-kB↓, 1,   p‑NF-kB↑, 2,   NK cell↑, 7,   NLRP3↓, 3,   NLRP3↑, 2,   NOD1↓, 1,   p65↓, 4,   p‑p65↓, 2,   PD-1↓, 3,   PD-1↝, 2,   PD-L1↓, 11,   PGE1↓, 1,   PGE2↓, 22,   PSA↓, 12,   SOCS-3↓, 1,   T-Cell↑, 1,   TCF↓, 1,   Th1 response↑, 1,   TLR4↓, 5,   TLR4↝, 1,   TNF-α↓, 37,   TNF-α↑, 5,   TNFRSF25/DR3/APO3/LARD/TRAMP/WSL1↑, 1,   Treg lymp↓, 3,  

Cellular Microenvironment(tgid=17) ⓘ

pH↓, 1,   pH↑, 1,   e-pH↑, 2,   i-pH↓, 1,   TAMS↓, 1,   TAMS↝, 1,  

Synaptic & Neurotransmission(tgid=18) ⓘ

5HT↓, 1,   PTN↓, 1,   SYN1↑, 1,  

Protein Aggregation(tgid=19) ⓘ

XO↓, 1,  

Hormonal & Nuclear Receptors(tgid=20) ⓘ

2/16-OHE1↑, 1,   2/16-OHE1↝, 1,   AhR↓, 1,   AhR↓, 1,   AR↓, 17,   AR↝, 2,   AR-FL↓, 1,   AR-V7↑, 1,   COMT↓, 2,   CYP17A1↓, 1,   CYP19↓, 2,   ENL↑, 1,   ER(estro)↓, 2,   ERα/ESR1↓, 1,   Estro↝, 1,   FGF21↓, 1,   FKBP5↓, 1,   PPARα↓, 2,   PPARγ↓, 1,   PPARγ↑, 3,   RANKL↓, 2,  

Drug Metabolism & Resistance(tgid=21) ⓘ

ABCG2↓, 1,   BioAv↓, 175,   BioAv↑, 235,   BioAv⇅, 2,   BioAv↝, 74,   BioEnh?, 1,   BioEnh↑, 7,   CBR1↓, 1,   chemoR↓, 2,   ChemoSen?, 1,   ChemoSen↓, 2,   ChemoSen↑, 197,   ChemoSen⇅, 2,   CompStab?, 1,   CompStab↓, 7,   CompStab↑, 7,   CompStab↝, 3,   CYP1A1↓, 6,   CYP1A1↑, 2,   CYP1A2↓, 1,   CYP1A2↑, 2,   CYP2A3/CYP2A6↓, 1,   CYP2C9↓, 1,   CYP2E1↑, 1,   CYP3A2↓, 1,   CYP3A4↓, 4,   DDS↑, 10,   Dose?, 4,   Dose↓, 4,   Dose↑, 16,   Dose↝, 90,   Dose∅, 11,   DrugR↓, 1,   eff?, 1,   eff↓, 28,   eff↑, 129,   eff⇅, 1,   eff↝, 13,   eff∅, 3,   GSTA1↑, 2,   GSTM1↑, 1,   GSTZ1↓, 1,   GSTZ1↝, 1,   Half-Life↓, 33,   Half-Life↑, 12,   Half-Life↝, 36,   Half-Life∅, 5,   MDR1↓, 10,   MRP↓, 1,   MRP1/ABCC1↓, 5,   MRP1/ABCC1↑, 1,   MRP1/ABCC1↝, 1,   P-gp/ABCB1↓, 22,   P-gp/ABCB1↑, 3,   P-gp/ABCB1⇅, 1,   P450↓, 4,   RadioS?, 1,   RadioS↑, 69,   RadioS↝, 1,   selectivity?, 1,   selectivity↑, 86,   selectivity↝, 1,   selectivity∅, 1,   Synergy↑, 111,   Synergy↝, 1,  

Clinical Biomarkers(tgid=22) ⓘ

AFP↓, 1,   ALAT↓, 6,   ALAT↑, 1,   ALP↓, 2,   AR↓, 17,   AR↝, 2,   ascitic↓, 1,   AST↓, 4,   AST↑, 1,   BMD↑, 1,   BP↓, 2,   BRAF↓, 1,   BRCA1↓, 2,   p‑BRCA1↑, 1,   CEA↓, 2,   CEC↝, 1,   CRP↓, 2,   E6↓, 2,   E7↓, 2,   EGFR↓, 30,   EGFR↑, 2,   p‑EGFR↓, 1,   ERα/ESR1↓, 1,   EZH2↓, 5,   Ferritin↓, 1,   FOXM1↓, 4,   HER2/EBBR2↓, 7,   hTERT/TERT↓, 13,   IL6↓, 38,   KRAS↓, 2,   LDH↓, 5,   LDH↑, 1,   LDH↝, 1,   Myc↓, 5,   NOS2↓, 1,   NOS2↑, 1,   NSE↓, 1,   PD-L1↓, 11,   PSA↓, 12,   TF-Ag↓, 1,   TG/TAG↓, 1,   TP53↑, 4,   TRIB3↑, 3,  

Functional Outcomes(tgid=23) ⓘ

AntiAge↑, 2,   AntiArt↑, 1,   AntiCan↓, 3,   AntiCan↑, 79,   AntiCan∅, 1,   antiD↑, 1,   AntiDiabetic↑, 1,   antiNeop↑, 3,   antiPs↑, 1,   AntiTum↑, 29,   cachexia↓, 3,   cardioP↑, 22,   CardioT↓, 1,   CardioT↑, 1,   chemoP↑, 41,   chemoPv↑, 22,   ChemoSideEff↓, 7,   cognitive?, 1,   cognitive↑, 4,   fatigue↓, 2,   hepatoP↓, 3,   hepatoP↑, 14,   memory↑, 4,   Mucositis↓, 1,   neuroP↑, 13,   NP/CIPN↓, 3,   NP/CIPN↑, 1,   Obesity↓, 1,   ORR↑, 1,   OS↑, 18,   OS↝, 1,   OS∅, 1,   Pain↓, 5,   PFS↓, 1,   PFS↑, 1,   PFS∅, 1,   QoL↑, 5,   QoL↝, 1,   radioP↑, 10,   Remission↑, 2,   RenoP↑, 5,   Risk↓, 29,   Risk↑, 1,   Sleep↑, 1,   toxicity↓, 38,   toxicity↑, 8,   toxicity⇅, 2,   toxicity↝, 21,   toxicity∅, 4,   TumVol↓, 20,   TumW↓, 7,   Weight↑, 1,   Wound Healing↑, 2,  

Infection & Microbiome(tgid=24) ⓘ

AntiBio↓, 1,   AntiViral↑, 1,   Bacteria↓, 1,   Dectin1↝, 1,   GutMicro↑, 11,   GutMicro↝, 1,   Sepsis↓, 3,  

Ingredients & Constituents(tgid=25) ⓘ

Ingr?, 2,   Ingr↝, 2,  
Total Targets: 1036

Pathway results for Effect on Normal Cells:


NA, unassigned(tgid=0) ⓘ

NA↓, 1,  

Redox & Oxidative Stress(tgid=1) ⓘ

4-HNE↓, 1,   antiOx?, 1,   antiOx↓, 16,   antiOx↑, 188,   ARE↑, 4,   ARE↝, 1,   Catalase↓, 1,   Catalase↑, 67,   Fenton↓, 2,   GPx↓, 1,   GPx↑, 53,   GPx1↑, 2,   GPx4↑, 1,   GSH↓, 1,   GSH↑, 65,   GSR↑, 9,   GSTs↓, 3,   GSTs↑, 17,   H2O2↓, 7,   H2O2↑, 1,   H2O2∅, 2,   HDL↑, 5,   HDL∅, 1,   HNE↓, 1,   HO-1↓, 2,   HO-1↑, 46,   HO-2↓, 1,   Iron↓, 1,   Keap1↓, 2,   Keap1↑, 2,   Keap1↝, 1,   lipid-P↓, 57,   mt-lipid-P↓, 1,   MDA↓, 51,   MPO↓, 10,   NADH↓, 1,   NOX↓, 1,   NQO1↑, 10,   NQO1↝, 1,   NQO1∅, 1,   Nrf1↑, 2,   NRF2?, 1,   NRF2↓, 3,   NRF2↑, 74,   NRF2⇅, 1,   NRF2↝, 1,   Prx↑, 1,   RNS↓, 5,   ROS?, 1,   ROS↓, 222,   ROS↑, 4,   ROS⇅, 4,   ROS∅, 2,   mt-ROS?, 1,   selenoP↑, 4,   SOD↓, 5,   SOD↑, 96,   mt-SOD↑, 1,   SOD1↑, 5,   SOD2↑, 3,   TAC↑, 7,   TBARS↓, 2,   Thiols↑, 1,   Trx↑, 2,   Trx1↑, 1,   TrxR↑, 1,   uricA↓, 3,   VitC↑, 5,   VitE↑, 4,  

Metal & Cofactor Biology(tgid=2) ⓘ

Ferritin↓, 1,   Ferritin↑, 1,   FPN↑, 1,   IronCh↑, 13,   IronCh↝, 1,   Mets↝, 1,   TfR1/CD71↑, 1,  

Mitochondria & Bioenergetics(tgid=3) ⓘ

compI↑, 2,   compII↑, 2,   compIII↑, 2,   compIV↑, 1,   DRP1/DNM1L↓, 1,   ETC↑, 1,   Insulin↓, 2,   Insulin↑, 4,   Insulin↝, 1,   MFN2↑, 1,   mtDam↓, 4,   OCR↓, 1,   OCR↑, 2,   OXPHOS↑, 1,   PGC-1α↑, 4,   PGC-1α↝, 1,   PINK1↑, 1,   SIRT3↑, 1,  

Core Metabolism/Glycolysis(tgid=4) ⓘ

12LOX↓, 2,   15-LOX/ALOX15↓, 1,   5LO↓, 5,   ACC↓, 1,   Acetyl-CoA↑, 1,   adiP↑, 1,   ALAT↓, 18,   ALAT∅, 2,   AMPK↓, 2,   AMPK↑, 16,   AMPK↝, 1,   ATP↓, 1,   ATP↑, 11,   Buty↑, 1,   cAMP↑, 2,   CRM↑, 1,   cytoP450↓, 1,   DHODH↓, 1,   FABP4↓, 1,   FAO↑, 1,   FASN↓, 1,   FFA/NEFA↓, 1,   G6PD↑, 1,   glucose↓, 8,   glucose↝, 4,   GlucoseCon↑, 5,   GlutMet↑, 1,   glyC↓, 1,   Glycolysis↓, 1,   GSK‐3β↓, 13,   GSK‐3β↑, 3,   p‑GSK‐3β↑, 1,   H2S↑, 1,   HMG-CoA↓, 2,   LDHA↑, 1,   LDL↓, 15,   lipidLev↓, 6,   lipoGen↓, 1,   NAD↓, 1,   NAD↑, 2,   NADH:NAD↑, 1,   NADPH↓, 3,   NADPH↑, 4,   PDK1 / PDPK1↓, 1,   PFK↓, 1,   PLA2↓, 2,   SCFAs↑, 1,   SIRT1↑, 21,   SIRT1↝, 1,   SIRT2↑, 1,   SREBF2↓, 1,   SREBF2⇅, 1,   SREBP1/SREBF1↓, 1,   SREBP1/SREBF1↑, 1,  

Cell Death(tgid=5) ⓘ

AIF↓, 1,   Apoptosis↓, 15,   ASC↓, 1,   BAX↓, 11,   Bax:Bcl2↓, 2,   Bcl-2↓, 3,   Bcl-2↑, 9,   Casp1↓, 1,   Casp12↓, 1,   Casp3↓, 24,   cl‑Casp3↓, 1,   Casp6↓, 1,   Casp8↓, 1,   Casp9↓, 11,   Casp9↑, 1,   Cyt‑c↓, 5,   Cyt‑c∅, 1,   Fas↓, 1,   Ferroptosis↓, 2,   GranB/GZMB↓, 1,   iNOS↓, 27,   iNOS↑, 1,   necrosis↓, 1,   p38↓, 3,   Pyro↓, 1,  

Kinase & Signal Transduction(tgid=6) ⓘ

Akt↓, 5,   Akt↑, 19,   Akt↝, 1,   p‑Akt↓, 1,   p‑Akt↑, 3,   Akt2↓, 1,   AMPKα↑, 1,   CREB↑, 4,   p‑CREB↑, 1,   ERK↓, 6,   ERK↑, 5,   p‑ERK↑, 3,   HGF/c-Met↑, 1,   IGF-1R↓, 1,   IKKα↓, 2,   JAK↓, 2,   JAK2↓, 1,   JAK2↑, 1,   JNK↓, 7,   p‑JNK↓, 3,   MAPK↓, 17,   MAPK↑, 2,   MAPK↝, 2,   mTOR↓, 3,   mTOR↑, 5,   mTOR↝, 1,   P70S6K↓, 1,   PDGFR-BB↓, 1,   PI3K↓, 5,   PI3K↑, 10,   PI3K↝, 1,   PKCδ↓, 2,   PKCδ↑, 2,   PP2A↑, 1,   PTEN↓, 2,   PTEN↑, 1,   STAT↓, 2,   STAT3↓, 3,   STAT3↑, 3,   p‑STAT3↑, 1,  

Transcription & Epigenetics(tgid=7) ⓘ

Ac-histone H3↑, 1,   AntiThr↑, 7,   ATF2↑, 1,   ATF4↓, 3,   DNMT1↓, 1,   FOXO↑, 1,   FOXO3↑, 1,   H3↑, 1,   H4↑, 1,   HATs↓, 1,   HDAC↓, 3,   HDAC↑, 2,   HDAC1↓, 1,   HDAC2↓, 1,   HDAC3↓, 2,   HOTAIR↑, 1,   other?, 3,   other↓, 10,   other↑, 23,   other↝, 41,   PhotoS↑, 1,   SOX2↑, 1,  

Protein Folding & ER Stress(tgid=8) ⓘ

CHOP/DDIT3↓, 4,   CHOP/DDIT3↑, 1,   eIF2α↓, 1,   p‑eIF2α↓, 1,   ER Stress↓, 7,   GRP78/BiP↓, 4,   GRP78/BiP↑, 2,   GRP94↑, 1,   HSP70/HSPA5↑, 3,   HSP70/HSPA5↝, 1,   HSP90↑, 1,   HSPs↑, 2,   IRE1↓, 1,   PERK↓, 1,   UPR↑, 1,   XBP-1↓, 1,  

Autophagy & Lysosomes(tgid=9) ⓘ

Beclin-1/ATG6↓, 5,   Beclin-1/ATG6↑, 1,   LC3‑Ⅱ/LC3‑Ⅰ↑, 1,   LC3II↓, 2,   LC3II↑, 1,   MitoP↓, 1,   p62↑, 1,   PARK2↑, 1,  

DNA Damage & Repair(tgid=10) ⓘ

p‑BRCA1↑, 1,   DNAdam↓, 13,   DNArepair↑, 3,   P53↓, 3,   PARP1↓, 1,   PCNA↓, 2,   Telomerase↓, 1,   TOP1↓, 1,  

Cell Cycle & Senescence(tgid=11) ⓘ

CDK2↓, 1,   CDK4↓, 1,   cycD1/CCND1↓, 1,   cycE/CCNE↓, 1,   E2Fs↑, 1,   GADD34↓, 1,   Ki-67↓, 2,   Ki-67↑, 1,   P21↓, 1,   RB1↓, 1,   TumCCA↑, 1,  

Proliferation, Differentiation & Cell State(tgid=12) ⓘ

CEBPA↓, 1,   Choline↑, 2,   Diff↝, 1,   FGF↑, 1,   GH↑, 1,   HH↓, 1,   HMGCR↓, 1,   IGF-1↓, 1,   IGF-1↑, 1,   IGFBP3↑, 1,   Ki-67↓, 2,   Ki-67↑, 1,   Nestin↑, 1,   neuroG↑, 8,   NOTCH1↑, 1,   TumCP↓, 1,  

Migration(tgid=13) ⓘ

AntiAg↓, 3,   AntiAg↑, 25,   AP-1↓, 7,   BACH1↓, 1,   Ca+2↓, 3,   Ca+2↑, 2,   Ca+2↝, 1,   Cartilage↑, 2,   COL1↓, 3,   Fibrosis↓, 1,   LRP1↑, 1,   MLC2/MYL9↝, 1,   MMP13↓, 2,   MMP2↓, 2,   MMP2↑, 2,   MMP3↓, 1,   MMP9↓, 10,   MMPs↓, 4,   MUC1↑, 1,   N-cadherin↑, 1,   Rho↓, 1,   ROCK1↓, 1,   p‑SMAD2↓, 2,   p‑SMAD3↓, 1,   p‑SMAD3↑, 1,   p‑T-cadherin↓, 1,   TGF-β↓, 5,   TGF-β↑, 2,   TGF-β1↓, 2,   TGF-β1↑, 1,   TIMP1↓, 1,   TregCell↑, 1,   TXNIP↓, 1,   uPA↑, 1,   α-SMA↓, 4,  

Angiogenesis & Vasculature(tgid=14) ⓘ

angioG↓, 2,   angioG↑, 3,   CD31/PECAM-1↑, 1,   E-sel↓, 1,   NO↓, 20,   NO↑, 3,   TXA2↓, 2,   VCAM-1↓, 8,   VEGF↓, 2,   VEGF↑, 3,  

Barriers & Transport(tgid=15) ⓘ

BBB?, 1,   BBB↓, 7,   BBB↑, 53,   BBB↝, 3,   BBB∅, 3,   EPR↑, 1,   GastroP↑, 6,   GLUT2↑, 2,   GLUT3↑, 1,   GLUT4↑, 3,   H+/K+-ATPase↓, 1,   IBI↑, 5,   memfluid↑, 2,   MMP↓, 1,   MMP↑, 16,   MMP∅, 1,   MUC19↓, 1,   MUC2↓, 1,   OCLN↓, 1,   OCLN↝, 1,   TJ↑, 3,   TRPA1↑, 1,   TRPV1↑, 2,   TRPV3↑, 2,   VGSC↓, 1,   ZO-1↓, 1,   ZO-1↑, 1,  

Immune & Inflammatory Signaling(tgid=16) ⓘ

AIF1/Iba-1↓, 1,   CB2 / CNR2↑, 1,   CD4+↑, 2,   CD8+↑, 1,   COX1↓, 9,   COX2/PTGS2↓, 57,   COX2/PTGS2↑, 1,   CXCR4↓, 1,   HMGB1↓, 2,   ICAM-1↓, 5,   IFN-γ↓, 5,   IFN-γ↑, 1,   IL1↓, 5,   IL10↓, 5,   IL10↑, 6,   IL12↓, 2,   IL17↓, 4,   IL18↓, 3,   IL1α∅, 1,   IL1β↓, 47,   IL1β∅, 1,   IL2↓, 5,   IL22↓, 1,   IL33↓, 1,   IL4↓, 5,   IL4↑, 1,   IL5↓, 2,   IL6↓, 55,   IL6↑, 3,   IL8↓, 12,   IL8↑, 1,   IL8∅, 1,   Imm↓, 2,   Imm↑, 20,   Imm⇅, 1,   Imm↝, 2,   INF-γ↓, 1,   Inflam?, 1,   Inflam↓, 216,   Inflam↑, 6,   IRF3↓, 1,   LPS↓, 1,   pol-M2 MC↑, 1,   MCP1/CCL2↓, 5,   MCP1/CCL2↑, 1,   MCP1/CCL2∅, 1,   MCT1↓, 1,   MIP‑1α/CCL3↓, 1,   MyD88↓, 1,   NeuroI↓, 3,   NF-kB↓, 77,   NF-kB↑, 3,   p‑NF-kB↓, 1,   NLRP3↓, 14,   NLRP3↑, 2,   p65↓, 2,   PGE2↓, 19,   RAGE↓, 3,   RANTES↓, 1,   TLR2↓, 4,   TLR3↓, 1,   TLR4↓, 9,   TLR4↑, 1,   TNF-α↓, 79,   TNF-α↑, 2,   VitD↑, 1,  

Cellular Microenvironment(tgid=17) ⓘ

GFAP↓, 1,  

Synaptic & Neurotransmission(tgid=18) ⓘ

5HT↓, 1,   5HT↑, 6,   Ach↑, 6,   AChE↓, 30,   AChE↑, 2,   ADAM10↑, 3,   BChE↓, 9,   BDNF↓, 1,   BDNF↑, 19,   ChAT↑, 6,   GABA↑, 5,   MAOA↓, 6,   MAOA↝, 1,   MAOB↓, 2,   monoA↑, 1,   NGF↑, 6,   PSD95↑, 4,   SNAP25↑, 2,   TPH1↓, 1,   TrkB↑, 4,  

Protein Aggregation(tgid=19) ⓘ

AGEs↓, 7,   APOE4↓, 1,   APP↓, 6,   cl‑APP↑, 1,   Aβ↓, 54,   Aβ42↓, 4,   BACE/β-secretase↓, 15,   PSEN1/PS1↑, 1,   tau↓, 16,   p‑tau↓, 7,   XO↓, 1,   XO↝, 1,   β-Amyloid↓, 1,  

Hormonal & Nuclear Receptors(tgid=20) ⓘ

ACE/ACE1↓, 1,   ACE2↓, 1,   cortisol↑, 1,   CYP19↓, 2,   DHT↑, 1,   GLP-1R↑, 1,   GR↑, 1,   PPARα↑, 4,   PPARγ↓, 3,   PPARγ↑, 8,   p‑PPARγ↓, 1,   SHBG↓, 1,  

Drug Metabolism & Resistance(tgid=21) ⓘ

ABC↓, 1,   BioAv?, 2,   BioAv↓, 210,   BioAv↑, 352,   BioAv⇅, 4,   BioAv↝, 171,   BioAv∅, 3,   BioEnh↑, 6,   ChemoSen↑, 4,   CompStab↓, 1,   CompStab↑, 10,   CompStab↝, 3,   CYP1A1↑, 1,   CYP1A2↑, 1,   CYP2E1↓, 2,   CYP3A2↓, 1,   DDS↑, 1,   Dose?, 4,   Dose↑, 9,   Dose⇅, 2,   Dose↝, 117,   Dose∅, 4,   eff↓, 5,   eff↑, 58,   eff↝, 7,   GSTA1↓, 1,   GSTA1↑, 1,   Half-Life?, 2,   Half-Life↓, 34,   Half-Life↑, 19,   Half-Life↝, 58,   Half-Life∅, 6,   MRP1/ABCC1↓, 1,   P-gp/ABCB1↓, 7,   P450↓, 3,   P450↑, 2,   P450↝, 1,   Synergy↑, 34,  

Clinical Biomarkers(tgid=22) ⓘ

ALAT↓, 18,   ALAT∅, 2,   ALB↑, 1,   ALP↓, 4,   anemia↓, 1,   AST↓, 20,   AST∅, 2,   BG↓, 2,   BloodF↑, 7,   BMD↑, 5,   BP↓, 17,   BP↝, 1,   p‑BRCA1↑, 1,   creat↓, 3,   CRP↓, 8,   Ferritin↓, 1,   Ferritin↑, 1,   HemoG↑, 1,   HOMA↓, 1,   hs-CRP↓, 3,   IL6↓, 55,   IL6↑, 3,   IRes↓, 1,   IRes↑, 2,   IRes↝, 1,   LDH↓, 6,   NOS2↓, 2,   RAGE↓, 3,   RBC↑, 1,   TC↓, 2,   TG/TAG↓, 2,   TMAO↓, 1,   Urea↓, 1,   VitD↑, 1,  

Functional Outcomes(tgid=23) ⓘ

Analgesic↑, 5,   AntiAge↑, 12,   antiAll↑, 19,   AntiArt↑, 8,   AntiCan↓, 1,   AntiCan↑, 35,   antiCG↝, 1,   AntiDiabetic↓, 2,   AntiDiabetic↑, 48,   AntiMyl↑, 1,   antiPs↑, 4,   AntiTum↓, 2,   AntiTum↑, 6,   Appetite↓, 1,   cardioP↓, 2,   cardioP↑, 95,   cardioP⇅, 1,   CardioT↓, 2,   chemoP↑, 15,   chemoPv↑, 13,   cognitive↓, 2,   cognitive↑, 76,   cognitive↝, 1,   cognitive∅, 2,   cough?, 1,   diuretic↑, 3,   hepatoP↓, 3,   hepatoP↑, 67,   Learn↑, 5,   memory↓, 1,   memory↑, 60,   motorD↓, 1,   motorD↑, 10,   Mucositis↓, 2,   neuroP↓, 2,   neuroP↑, 168,   neuroP↝, 1,   Obesity↓, 26,   OS↑, 4,   Pain↓, 11,   radioP↑, 9,   RenoP↓, 1,   RenoP↑, 20,   RenoP↝, 1,   Risk↓, 6,   Risk↑, 3,   Sleep↑, 2,   SoreThr?, 1,   Strength↑, 2,   Stroke↓, 16,   toxicity?, 2,   toxicity↓, 75,   toxicity↑, 13,   toxicity⇅, 1,   toxicity↝, 27,   toxicity∅, 12,   Weight↓, 4,   Weight↝, 1,   Wound Healing↑, 8,  

Infection & Microbiome(tgid=24) ⓘ

AntiBio↑, 20,   AntiFungal↑, 7,   AntiP↑, 1,   AntiViral↑, 16,   Bacteria↓, 40,   Diar↓, 2,   GutMicro↑, 40,   GutMicro↝, 2,   Sepsis↓, 4,  

Ingredients & Constituents(tgid=25) ⓘ

Ingr?, 1,   Ingr↑, 5,   Ingr↝, 8,  
Total Targets: 622

Scientific Paper Hit Count for: BioAv, bioavailability
49 Curcumin
21 Sulforaphane (mainly Broccoli)
20 chitosan
20 Quercetin
20 EGCG (Epigallocatechin Gallate)
18 Baicalein
18 Chlorogenic acid
17 Resveratrol
15 Berberine
15 Selenium NanoParticles
15 Chrysin
15 Luteolin
15 Lycopene
14 Apigenin (mainly Parsley)
14 Pterostilbene
13 Kaempferol
12 Thymoquinone
11 Silymarin (Milk Thistle) silibinin
11 Honokiol
10 Alpha-Lipoic-Acid
10 Rosmarinic acid
10 Magnolol
9 Astaxanthin
9 borneol
9 Carvacrol
9 Morin
9 Urolithin
8 Broccoli
8 Capsaicin
8 Crocetin
8 Diindolylmethane
8 Emodin
8 Ferulic acid
8 Fucoidan
8 Piperlongumine
7 Allicin (mainly Garlic)
7 Artemisinin
7 Betulinic acid
7 Hydroxycinnamic-acid
7 Piperine
7 Fisetin
7 Flaxseed/Linseed
7 HydroxyTyrosol
7 Isoliquiritigenin
7 isoquercitrin
7 Phenethyl isothiocyanate
6 Silver-NanoParticles
6 Ashwagandha(Withaferin A)
6 Biochanin A
6 Rutin
6 Propolis -bee glue
6 Ellagic acid
6 Eugenol
5 beta-glucans
5 Baicalin
5 Boswellia (frankincense)
5 Thymol-Thymus vulgaris
5 Centella asiatica / Gotu kola → asiaticoside
5 Cucurbitacin
5 Formononetin
5 SDG/lignans
5 Gallic acid
5 Inositol
5 Naringin
5 Selenite (Sodium)
4 1,8-Cineole
4 5-Hydroxytryptophan
4 Beta-Caryophyllene
4 Boron
4 Caffeic acid
4 Melatonin
4 Celastrol
4 phytic acid, Inositol hexakisphosphate
4 Garcinol
4 Isovitexin
4 Lactoferrin/Talactoferrin
4 Matrine
4 Phenylbutyrate
4 Vitamin C (Ascorbic Acid)
4 Shikonin
4 Aflavin-3,3′-digallate
3 Ascorbyl Palmitate
3 Gold NanoParticles
3 Berbamine
3 Folic Acid, Vit B9
3 Chocolate
3 Cinnamon
3 Coenzyme Q10
3 Copper and Cu NanoParticles
3 Diclofenac
3 Indole-3-carbinol
3 Disulfiram
3 Fenbendazole
3 Gambogic Acid
3 Genistein (soy isoflavone)
3 Glabrescione B
3 Gossypol/AT-101
3 Grapeseed extract
3 Lapatinib
3 Licochalcone A
3 Licorice
3 Lecithin
3 Linalool
3 Lutein
3 Methylene blue
3 mebendazole
3 Metformin
3 Magnetic Fields
3 Niclosamide (Niclocide)
3 Selenium
3 Silicic Acid
3 Spermidine
3 Terpinen-4-ol / Tea Tree Oil
2 3-bromopyruvate
2 Auranofin
2 Astragalus
2 Citric Acid
2 Aspirin
2 Paclitaxel/Taxol
2 Atorvastatin
2 immunotherapy
2 doxorubicin
2 Docetaxel
2 Radiotherapy/Radiation
2 buckwheat sprouts
2 Butyrate
2 Cynanbungeigenin C (CBC) and D (CBD)
2 Chlorophyllin
2 Choline
2 Camptothecin
2 Cynara scolymus/Globe Artichoke/Artichoke Extract
2 Dasatinib/Phyrago
2 Dichloroacetate
2 Deguelin
2 D-limonene
2 Evodiamine
2 flavonoids
2 MCT oil
2 Shilajit/Fulvic Acid
2 Geraniol
2 Ginkgolide B
2 Ginkgetin
2 Hydrogen Gas
2 HydroxyCitric Acid
2 isoflavones
2 isoorientin
2 itraconazole
2 Ivermectin
2 Lapachol
2 Lemongrass Extract/Citral
2 Methyl salicylate / Sweet Birch oil
2 magnetic nanoparticles
2 Magnesium
2 Mushroom Lion’s Mane, Hericium erinaceus
2 nicotinamide adenine dinucleotide
2 Oleuropein
2 Turmerones
2 Ursolic acid
1 Aluminum
1 Anethole/trans-Anethole
1 Aromatherapy
1 Gemcitabine (Gemzar)
1 Aloe anthraquinones
1 xanthohumol
1 beta-carotene(VitA)
1 Bicalutamide
1 Bacopa monnieri
1 α-Bisabolol / Chamomile oil
1 Bullatacin
1 Carnosic acid
1 urea
1 capecitabine
1 Catechins
1 Cat’s Claw
1 Cannabidiol
1 Zinc
1 Citicoline, CDP-Choline
1 irinotecan
1 Polyphenols
1 Cyclopamine
1 Dichloroacetophenone(2,2-)
1 Dandelion Root
1 Echinacea
1 Ginkgo biloba-EGb 761
1 Electrical Pulses
1 Eurycomanone
1 Sesame seeds and Oil
1 Mung Bean Sprouts
1 tamoxifen
1 Gamma-aminobutyric acid
1 Ginkgo biloba
1 Germanium Organic/Ge-132 / propagermanium (organogermanium)
1 Geldanamycin
1 Ginger/6-Shogaol/Gingerol
1 Ginseng
1 Arsenic trioxide
1 Graviola
1 Germacranolide sesquiterpene lactone
1 Hibiscus sabdariffa
1 Hyperthermia
1 Huperzine A/Huperzia serrata
1 Hyperoside
1 Isobavachalcone
1 iodine
1 Anthocyanins
1 L-Theanine
1 Modified Citrus Pectin
1 Bicarbonate(Sodium)
1 Oleocanthal
1 Oxygen, Hyperbaric
1 Cisplatin
1 Psoralidin
1 Parthenolide
1 enzalutamide
1 Rauwolfia serpentina/Indian Snakeroot
1 salinomycin
1 Chemotherapy
1 Date Fruit Extract
1 cetuximab
1 Tomatine
1 Vitamin B3,Niacin
1 Vitamin D3
1 Vitamin E
1 Vitamin K2
1 Vitexin
Query results interpretion may depend on "conditions" listed in the research papers.
Such Conditions may include : 
  -low or high Dose
  -format for product, such as nano of lipid formations
  -different cell line effects
  -synergies with other products 
  -if effect was for normal or cancerous cells

Filter Conditions: Pro/AntiFlg:%  IllCat:%  CanType:%  Cells:%  prod#:%  Target#:792  State#:%  Dir#:%
  wNotes=0  sortOrder:rid,rpid

 

Home Page