| 7029- | GA, | Gallic acid induces G1 phase arrest and apoptosis of triple-negative breast cancer cell MDA-MB-231 via p38 mitogen-activated protein kinase/p21/p27 axis |
| - | in-vitro, | BC, | MDA-MB-231 | - | in-vitro, | BC, | HS587T | - | in-vitro, | Nor, | MCF10 |
| 7028- | GA, | Gallic acid: Pharmacological activities and molecular mechanisms involved in inflammation-related diseases |
| - | Review, | Nor, | NA |
| 7027- | GA, | Pharmacokinetics of gallic acid and its relative bioavailability from tea in healthy humans |
| - | Human, | Nor, | NA |
| 1091- | GA, | Gallic acid reduces cell viability, proliferation, invasion and angiogenesis in human cervical cancer cells |
| - | in-vitro, | Cerv, | HeLa | - | in-vitro, | Cerv, | HTB-35 |
| 1115- | GA, | Gallic acid alleviates gastric precancerous lesions through inhibition of epithelial mesenchymal transition via Wnt/β-catenin signaling pathway |
| - | in-vivo, | GC, | GES-1 |
| 1086- | GA, | Anti-leukemic effects of gallic acid on human leukemia K562 cells: downregulation of COX-2, inhibition of BCR/ABL kinase and NF-κB inactivation |
| - | in-vitro, | AML, | K562 |
| 1065- | GA, | Gallic acid, a phenolic acid, hinders the progression of prostate cancer by inhibition of histone deacetylase 1 and 2 expression |
| - | vitro+vivo, | Pca, | NA |
| 987- | GA, | Targeting Aerobic Glycolysis: Gallic Acid as Promising Anticancer Drug |
| - | in-vitro, | GBM, | AMGM | - | in-vitro, | Cerv, | HeLa | - | in-vitro, | BC, | MCF7 |
| 997- | GA, | The Inhibitory Mechanisms of Tumor PD-L1 Expression by Natural Bioactive Gallic Acid in Non-Small-Cell Lung Cancer (NSCLC) Cells |
| - | in-vitro, | Lung, | A549 | - | in-vitro, | Lung, | H292 | - | in-vitro, | Nor, | HUVECs |
| 947- | GA, | Gallic acid, a phenolic compound, exerts anti-angiogenic effects via the PTEN/AKT/HIF-1α/VEGF signaling pathway in ovarian cancer cells |
| - | in-vitro, | Ovarian, | OVCAR-3 | - | in-vitro, | Melanoma, | A2780S | - | in-vitro, | Nor, | IOSE364 | - | Human, | NA, | NA |
| 7833- | GA, | Neuroprotective Potential of Mung Bean (Vigna radiata L.) Polyphenols in Alzheimer's Disease: A Review |
| - | Review, | AD, | NA |
| 1283- | GA, | immuno, | Gallic acid induces T-helper-1-like Treg cells and strengthens immune checkpoint blockade efficacy |
| - | vitro+vivo, | CRC, | NA |
| 1300- | GA, | PacT, | carbop, | Gallic acid potentiates the apoptotic effect of paclitaxel and carboplatin via overexpression of Bax and P53 on the MCF-7 human breast cancer cell line |
| - | in-vitro, | BC, | MCF7 |
| 1624- | GA, | Anticancer Effect of Pomegranate Peel Polyphenols against Cervical Cancer |
| - | in-vitro, | Cerv, | NA |
| 1773- | GA, | Impact of Gallic Acid on Gut Health: Focus on the Gut Microbiome, Immune Response, and Mechanisms of Action |
| - | Review, | Var, | NA |
| - | Trial, | Nor, | NA |
| 7071- | GABA, | Oral intake of γ-aminobutyric acid affects mood and activities of central nervous system during stressed condition induced by mental tasks |
| - | Trial, | Nor, | NA |
| 7070- | GABA, | Neurotransmitters as food supplements: the effects of GABA on brain and behavior |
| - | Review, | Nor, | NA |
| 7069- | GABA, | United States Pharmacopeia (USP) Safety Review of Gamma-Aminobutyric Acid (GABA) |
| - | Review, | Nor, | NA |
| 7075- | GABA, | Effects of γ-aminobutyric acid supplementation on glucose control in adults with prediabetes: A double-blind, randomized, placebo-controlled trial |
| - | Trial, | Diabetic, | NA |
| 7074- | GABA, | Effect of oral γ-aminobutyric acid (GABA) administration on sleep and its absorption in humans |
| - | Trial, | Nor, | NA |
| 7076- | GABA, | Anti-hypertensive effect of gamma-aminobutyric acid (GABA)-rich Chlorella on high-normal blood pressure and borderline hypertension in placebo-controlled double blind study |
| - | Trial, | Nor, | NA |
| - | Trial, | Nor, | NA |
| 7078- | GABA, | GABA attenuates amyloid toxicity by downregulating its endocytosis and improves cognitive impairment |
| - | in-vivo, | AD, | NA |
| 7079- | GABA, | GABAergic Inhibitory Interneuron Deficits in Alzheimer’s Disease: Implications for Treatment |
| - | Review, | AD, | NA |
| 7080- | GABA, | The Effect of Oral GABA on the Nervous System: Potential for Therapeutic Intervention |
| - | Review, | AD, | NA |
| 7081- | GABA, | Exploring the Therapeutic Potential of Gamma-Aminobutyric Acid in Stress and Depressive Disorders through the Gut–Brain Axis |
| - | Review, | AD, | NA |
| 7082- | GABA, | Contributions of Gamma-Aminobutyric Acid (GABA) Produced by Lactic Acid Bacteria on Food Quality and Human Health: Current Applications and Future Prospects |
| - | Review, | AD, | NA |
| 7083- | GABA, | Impact of oral supplementation of Glutamate and GABA on memory performance and neurochemical profile in hippocampus of rats |
| 7073- | GABA, | Safety and Efficacy of Gamma-Aminobutyric Acid from Fermented Rice Germ in Patients with Insomnia Symptoms: A Randomized, Double-Blind Trial |
| - | Trial, | Nor, | NA |
| 3719- | GABA, | Treatment Options in Alzheimer´s Disease: The GABA Story |
| - | Review, | AD, | NA |
| 3720- | GABA, | Effects of Oral Gamma-Aminobutyric Acid (GABA) Administration on Stress and Sleep in Humans: A Systematic Review |
| - | Review, | AD, | NA |
| 4248- | Gala, | Meta-analysis of randomized controlled trials of galantamine in schizophrenia: significant cognitive enhancement |
| - | Review, | NA, | NA |
| 7050- | Gallo, | Galloflavin suppresses lactate dehydrogenase activity and causes MYC downregulation in Burkitt lymphoma cells through NAD/NADH-dependent inhibition of sirtuin-1 |
| - | in-vitro, | lymphoma, | NA |
| 7051- | Gallo, | MET, | Galloflavin Plus Metformin Treatment Impairs Pancreatic Cancer Cells |
| - | in-vitro, | PC, | MIA PaCa-2 |
| 7052- | Gallo, | Galloflavin Relieves the Malignant Behavior of Colorectal Cancer Cells in the Inflammatory Tumor Microenvironment |
| - | in-vivo, | Colon, | SW48 |
| 7053- | Gallo, | Therapeutic Strategies Toward Lactate Dehydrogenase Within the Tumor Microenvironment of Pancreatic Cancer |
| - | in-vitro, | PC, | PANC1 | - | in-vitro, | PC, | MIA PaCa-2 | - | in-vitro, | PC, | Bxpc-3 |
| 935- | Gallo, | Galloflavin, a new lactate dehydrogenase inhibitor, induces the death of human breast cancer cells with different glycolytic attitude by affecting distinct signaling pathways |
| - | in-vitro, | BC, | MCF7 | - | in-vitro, | BC, | MDA-MB-231 |
| 934- | Gallo, | Galloflavin (CAS 568-80-9): a novel inhibitor of lactate dehydrogenase |
| - | Analysis, | NA, | NA |
| 5207- | Gallo, | Targeting pancreatic cancer with combinatorial treatment of CPI-613 and inhibitors of lactate metabolism |
| 5206- | Gallo, | Galloflavin prevents the binding of lactate dehydrogenase A to single stranded DNA and inhibits RNA synthesis in cultured cells |
| - | in-vitro, | Var, | NA |
| 5205- | Gallo, | Evaluation of the anti-tumor effects of lactate dehydrogenase inhibitor galloflavin in endometrial cancer cells |
| - | in-vitro, | Endo, | ISH |
| 7056- | GamB, | Gambogic acid induces cell death via covalent binding with PRDX1 to regulate ER stress and autophagy |
| - | in-vitro, | RCC, | 786-O |
| 7066- | GamB, | Unravelling the Therapeutic Potential of Gambogic Acid: Deciphering Its Molecular Mechanism of Action and Emerging Role as an Anticancer Xanthone |
| - | Review, | Var, | NA |
| 7065- | GamB, | Gambogic acid: A review of its pharmacological mechanisms against cancer |
| - | Review, | Var, | NA |
| 7064- | GamB, | Gambogic acid inhibits the catalytic activity of human topoisomerase IIα by binding to its ATPase domain |
| - | in-vitro, | GC, | SGC-7901 | - | in-vitro, | Liver, | Bel-7402 | - | in-vitro, | HCC, | SMMC-7721 cell | - | in-vitro, | Ovarian, | HO-8910 |
| 7063- | GamB, | Gambogic acid mediates apoptosis as a p53 inducer through down-regulation of mdm2 in wild-type p53-expressing cancer cells |
| - | vitro+vivo, | Lung, | H1299 |
| 7062- | GamB, | Chit, | Modified chitosan derivative micelle system for natural anti-tumor product gambogic acid delivery |
| - | in-vivo, | Nor, | NA |
| 7061- | GamB, | An open-labeled, randomized, multicentered, phase IIa study for advanced cancer treatment by gambogic acid injection (THS) |
| - | Trial, | Var, | NA |
| 7060- | GamB, | New targets for the antitumor activity of gambogic acid in hematologic malignancies |
| - | Review, | Melanoma, | RPMI-8226 |
Query results interpretion may depend on "conditions" listed in the research papers. Such Conditions may include : -low or high Dose -format for product, such as nano of lipid formations -different cell line effects -synergies with other products -if effect was for normal or cancerous cells
Filter Conditions: Pro/AntiFlg:% IllCat:% CanType:% Cells:% prod#:% Target#:% State#:% Dir#:%
wNotes=0 sortOrder:rid,rpid