| 5016- | PEITC, | Phenethyl Isothiocyanate (PEITC) interaction with Keap1 activates the Nrf2 pathway and inhibits lipid accumulation in adipocytes |
| - | in-vitro, | Nor, | NA |
| 4936- | PEITC, | PEITC treatment suppresses myeloid derived tumor suppressor cells to inhibit breast tumor growth |
| - | in-vivo, | BC, | MDA-MB-231 |
| 4937- | PEITC, | PEITC: Functional Compound for Primary and Tertiary Chemoprevention of Cancer |
| 4938- | PEITC, | Clinical Trial of 2-Phenethyl Isothiocyanate as an Inhibitor of Metabolic Activation of a Tobacco-Specific Lung Carcinogen in Cigarette Smokers |
| - | Trial, | Nor, | NA |
| 4939- | PEITC, | Phenethyl Isothiocyanate Inhibits Angiogenesis In vitro and Ex vivo |
| - | in-vitro, | Pca, | PC3 | - | ex-vivo, | Nor, | HUVECs |
| 4940- | PEITC, | Phenethyl Isothiocyanate (PEITC) Inhibits the Growth of Human Oral Squamous Carcinoma HSC-3 Cells through G 0/G 1 Phase Arrest and Mitochondria-Mediated Apoptotic Cell Death |
| - | in-vitro, | Oral, | HSC3 |
| 4941- | PEITC, | PEITC: A resounding molecule averts metastasis in breast cancer cells in vitro by regulating PKCδ/Aurora A interplay |
| - | in-vitro, | BC, | MCF-7 | - | in-vitro, | BC, | MDA-MB-231 |
| 4942- | PEITC, | Phenethyl Isothiocyanate (PEITC) Inhibits the Growth of Human Oral Squamous Carcinoma HSC-3 Cells through G(0)/G(1) Phase Arrest and Mitochondria-Mediated Apoptotic Cell Death |
| - | in-vitro, | Oral, | HSC3 |
| 4943- | PEITC, | Phenethyl isothiocyanate (PEITC) inhibits growth of ovarian cancer cells by inducing apoptosis: role of caspase and MAPK activation |
| - | in-vitro, | Ovarian, | OVCAR-3 |
| 5072- | PEITC, | Inhibition and Inactivation of Human Cytochrome P450 Isoforms by Phenethyl Isothiocyanate |
| - | in-vitro, | Nor, | NA |
| 5183- | PEITC, | Cisplatin, | Phenethyl Isothiocyanate Induces Apoptosis Through ROS Generation and Caspase-3 Activation in Cervical Cancer Cells |
| - | in-vitro, | Cerv, | HeLa | - | in-vitro, | Nor, | HaCaT |
| 5184- | PEITC, | Phenethyl isothiocyanate exhibits antileukemic activity in vitro and in vivo by inactivation of Akt and activation of JNK pathways |
| - | vitro+vivo, | AML, | U937 |
| 5185- | PEITC, | SFN, | Suppression of NF-kappaB and NF-kappaB-regulated gene expression by sulforaphane and PEITC through IkappaBalpha, IKK pathway in human prostate cancer PC-3 cells |
| - | in-vitro, | Pca, | PC3 |
| 5186- | PEITC, | Phenethyl Isothiocyanate inhibits STAT3 activation in prostate cancer cells |
| - | in-vitro, | Pca, | DU145 | - | in-vitro, | Pca, | LNCaP |
| 5187- | PEITC, | Phenethyl Isothiocyanate Inhibits Migration and Invasion of Human Gastric Cancer AGS Cells through Suppressing MAPK and NF-κB Signal Pathways |
| - | in-vitro, | GC, | AGS |
| 34- | PFB, | Naturally occurring small-molecule inhibitors of hedgehog/GLI-mediated transcription |
| - | in-vitro, | PC, | PANC1 |
| 5220- | PG, | TMZ, | Propyl Gallate Exerts an Antimigration Effect on Temozolomide-Treated Malignant Glioma Cells through Inhibition of ROS and the NF- κ B Pathway |
| - | in-vitro, | GBM, | U87MG |
| 5217- | PG, | Role of redox signaling regulation in propyl gallate-induced apoptosis of human leukemia cells |
| - | in-vitro, | AML, | THP1 | - | in-vitro, | AML, | Jurkat | - | in-vitro, | AML, | HL-60 |
| 5218- | PG, | Propyl gallate inhibits hepatocellular carcinoma cell growth through the induction of ROS and the activation of autophagy |
| - | in-vitro, | HCC, | Hep3B |
| 5219- | PG, | Propyl gallate inhibits the growth of HeLa cells via caspase-dependent apoptosis as well as a G1 phase arrest of the cell cycle |
| - | in-vitro, | Cerv, | HeLa |
| 1766- | PG, | Propyl gallate induces human pulmonary fibroblast cell death through the regulation of Bax and caspase-3 |
| - | in-vitro, | Nor, | NA |
| 1767- | PG, | Propyl gallate induces cell death in human pulmonary fibroblast through increasing reactive oxygen species levels and depleting glutathione |
| - | in-vitro, | Nor, | NA |
| 1768- | PG, | Propyl gallate reduces the growth of lung cancer cells through caspase‑dependent apoptosis and G1 phase arrest of the cell cycle |
| - | in-vitro, | Lung, | Calu-6 | - | in-vitro, | Lung, | A549 |
| 1769- | PG, | The Anti-Apoptotic Effects of Caspase Inhibitors in Propyl Gallate-Treated Lung Cancer Cells Are Related to Changes in Reactive Oxygen Species and Glutathione Levels |
| - | in-vitro, | Lung, | Calu-6 | - | in-vitro, | Lung, | A549 |
| 1770- | PG, | Propyl gallate sensitizes human lung cancer cells to cisplatin-induced apoptosis by targeting heme oxygenase-1 for TRC8-mediated degradation |
| - | in-vitro, | Lung, | NA |
| 1772- | PG, | Propyl gallate decreases the proliferation of Calu-6 and A549 lung cancer cells via affecting reactive oxygen species and glutathione levels |
| - | in-vitro, | Lung, | Calu-6 | - | in-vitro, | Lung, | A549 |
| 1774- | PG, | Geno- and cytotoxicity of propyl gallate food additive |
| - | in-vitro, | Lung, | A549 |
| 1771- | PG, | Pharmacokinetic and toxicological overview of propyl gallate food additive |
| - | Human, | Nor, | NA |
| 1764- | PG, | Cu, | DNA strand break induction and enhanced cytotoxicity of propyl gallate in the presence of copper(II) |
| - | in-vitro, | Nor, | GM05757 |
| 1763- | PG, | Generation of Hydrogen Peroxide in Cancer Cells: Advancing Therapeutic Approaches for Cancer Treatment |
| - | Review, | NA, | NA |
| 1765- | PG, | Enhanced cell death effects of MAP kinase inhibitors in propyl gallate-treated lung cancer cells are related to increased ROS levels and GSH depletion |
| - | in-vitro, | Lung, | A549 | - | in-vitro, | Lung, | Calu-6 |
| 1164- | PI, | Inhibition of T cell activation by the phytochemical piperine |
| - | in-vitro, | Nor, | NA |
| - | in-vitro, | NA, | NA |
| 1165- | PI, | Piperine inhibits IL-1β-induced IL-6 expression by suppressing p38 MAPK and STAT3 activation in gastric cancer cells |
| - | in-vitro, | GC, | TMK-1 |
| 1163- | PI, | The Effect of Piperine on MMP-9, VEGF, and E-cadherin Expression in Breast Cancer MCF-7 Cell Line |
| - | in-vitro, | BC, | MC38 |
| 1258- | PI, | Piperlongumine Alleviates Mouse Colitis and Colitis-Associated Colorectal Cancer |
| - | in-vivo, | CRC, | NA |
| 1257- | PI, | Piperlongumine attenuates bile duct ligation-induced liver fibrosis in mice via inhibition of TGF-β1/Smad and EMT pathways |
| - | ex-vivo, | LiverDam, | NA |
| 1256- | PI, | Hypoxia potentiates the cytotoxic effect of piperlongumine in pheochromocytoma models |
| - | in-vitro, | adrenal, | PHEO | - | in-vivo, | NA, | NA |
| 1255- | PI, | ALA, | Antileukemic effects of piperlongumine and alpha lipoic acid combination on Jurkat, MEC1 and NB4 cells in vitro |
| - | in-vitro, | CLL, | NA |
| 1254- | PI, | VitC, | Piperlongumine combined with vitamin C as a new adjuvant therapy against gastric cancer regulates the ROS–STAT3 pathway |
| - | in-vivo, | GC, | NA |
| 925- | PI, | Bioenhancers from mother nature and their applicability in modern medicine |
| - | Review, | Nor, | NA |
| 1016- | PI, | Piperine suppresses the Wnt/β-catenin pathway and has anti-cancer effects on colorectal cancer cells |
| - | in-vitro, | CRC, | HCT116 | - | in-vitro, | CRC, | SW480 | - | in-vitro, | CRC, | DLD1 |
| 1131- | PI, | Piperlongumine‑loaded nanoparticles inhibit the growth, migration and invasion and epithelial‑to‑mesenchymal transition of triple‑negative breast cancer cells |
| - | in-vitro, | BC, | MDA-MB-231 | - | in-vitro, | BC, | BT549 |
| 1059- | PI, | Piperine Inhibits TGF-β Signaling Pathways and Disrupts EMT-Related Events in Human Lung Adenocarcinoma Cells |
| - | in-vitro, | Lung, | A549 | - | in-vitro, | BC, | MDA-MB-231 | - | in-vitro, | Liver, | HepG2 |
| 3587- | PI, | Piperine: A review of its biological effects |
| - | Review, | Park, | NA | - | Review, | AD, | NA |
| 3589- | PI, | Anti-inflammatory and antiarthritic effects of piperine in human interleukin 1β-stimulated fibroblast-like synoviocytes and in rat arthritis models |
| - | in-vivo, | Arthritis, | NA |
| 3595- | PI, | Black pepper and health claims: a comprehensive treatise |
| - | Review, | Var, | NA | - | Review, | AD, | NA |
| 3596- | PI, | Antioxidant efficacy of black pepper (Piper nigrum L.) and piperine in rats with high fat diet induced oxidative stress |
| - | in-vivo, | Nor, | NA |
| 3597- | PI, | Chronic diseases, inflammation, and spices: how are they linked? |
| - | Review, | AD, | NA | - | Review, | Park, | NA | - | Review, | Var, | NA |
| 3598- | PI, | Piperine attenuates cognitive impairment in an experimental mouse model of sporadic Alzheimer's disease |
| - | in-vivo, | AD, | NA |
Query results interpretion may depend on "conditions" listed in the research papers. Such Conditions may include : -low or high Dose -format for product, such as nano of lipid formations -different cell line effects -synergies with other products -if effect was for normal or cancerous cells
Filter Conditions: Pro/AntiFlg:% IllCat:% CanType:% Cells:% prod#:% Target#:% State#:% Dir#:%
wNotes=0 sortOrder:rid,rpid