antiOx Cancer Research Results

antiOx, anti-oxidant activities: Click to Expand ⟱
Source:
Type:
Various antioxidants such as Nrf2, SODs, catalase, GPxs, PRDXs, and GSTs are altered in different cancers and have been linked to prognosis. Their overexpression can correlate with aggressive tumor behavior and resistance to treatment in many contexts.
Scientific Papers found: Click to Expand⟱
6906- FIS,  Rad,    Combining fisetin and ionizing radiation suppresses the growth of mammalian colorectal cancers in xenograft tumor models
- in-vivo, CRC, CT26 - in-vivo, CRC, HCT116
antiOx↑, Inflam↓, angioG↓, TumCI↓, TumCP↓, TumCG↓, RadioS↑,
6897- FIS,    Fisetin: A Dietary Antioxidant for Health Promotion
- Review, Nor, NA
*chemoPv↑, *neuroP↑, *antiOx↑, *GSH↑, *HO-1↑, *NRF2↑, angioG↓, TumCG↓, uPA↓, MMP1↓, tumCV↓, PTEN↑, PI3K↓, p‑Akt↓, AMPK↑, mTOR↓, EGFR↓, NF-kB↓, COX2/PTGS2↓, PGE2↓, Wnt↓, β-catenin/ZEB1↓, TCF↓, cycD1/CCND1↓, MMP7↓, RadioS↑, PSA↓, Securin↓, TumCCA↑, XIAP↓, *ERK↑, *p‑CREB↑, *memory↑, *GSH↑, *Inflam↓, *5LO↓,
6922- FIS,    Inhibition of Akt/mTOR signaling by the dietary flavonoid fisetin
- Review, Var, NA
*memory↑, *Inflam↓, *5LO↓, *lipid-P↓, *NF-kB↓, *antiOx↑, *GSH↑, *HO-1↑, *NRF2↑, *ROS↓, PI3K↓, Akt↓, TumCCA↑, cycD1/CCND1↓, cycE/CCNE↓, CDK2↓, CDK4↓, TumCMig↓, MMPs↓, PSA↓,
5392- FIS,  AsP,    Fisetin topical delivery via ascorbyl palmitate/hyaluronan-enhanced limosomes: a novel paradigm for preventing UVB-induced skin photoaging
- in-vivo, Nor, NA
eff↑, *antiOx↑, *MMP9↓, *TNF-α↓, *NF-kB↓, *SOD↑, *Catalase↑, *AntiAge↑, *Inflam↓, *JNK↓,
2313- Flav,    Flavonoids against the Warburg phenotype—concepts of predictive, preventive and personalised medicine to cut the Gordian knot of cancer cell metabolism
- Review, Var, NA
Warburg↓, antiOx↑, angioG↓, Glycolysis↓, PKM2↓, PKM2:PKM1↓, β-catenin/ZEB1↓, cMyc↓, HK2↓, Akt↓, mTOR↓, GLUT1↓, Hif1a↓,
6925- Flav,    Important Flavonoids and Their Role as a Therapeutic Agent
- Review, Nor, NA
AntiCan↑, *antiOx↑, *Inflam↓, *AntiViral↑, *neuroP↑, *cardioP↑, *AChE↓, *cognitive↑, Risk↓, *Stroke↓, *AntiDiabetic↑, *AntiFungal↑,
6924- Flav,    Plant Flavonoids: Chemical Characteristics and Biological Activity
- Review, Nor, NA
*ROS↓, *antiOx↑, *Inflam↓, *Bacteria↓, *cardioP↑, AntiCan↑, *AntiAge↑, *AntiDiabetic↑, AntiViral↑, *BioAv↓, *AntiFungal↑,
6923- Flav,    Flavonoids: an overview
- Review, Nor, NA
*antiOx↑, AntiCan↑, *cardioP↑, *XO↓, *COX2/PTGS2↓, *5LO↓, *PI3K↓, *AChE↓, *Imm⇅, *BP↓, TumCCA↑, *Aβ↓, *BACE/β-secretase↓, *NF-kB↓, *ROS↓, *neuroP↑, *AntiAg↑, *AntiThr↑,
7012- Fuc,    Fucoidan: A promising natural therapeutic agent for protecting human kidney health
- Review, EC, NA
*RenoP↑, *Inflam↓, *antiOx↑, *ROS↓, *BloodF↑, *diuretic↑, *BioAv↓, *BioAv↑, *MAPK↓, *ERK↑, *NLRP3↓, *NRF2↑, *MDA↓, *SOD↑, *GPx↑, *Catalase↑, *lipid-P↓, *DNAdam↓, *Fibrosis↓, *JAK2↓, *STAT3↓, *uricA↓, *COL1↓, *α-SMA↓, *SIRT1↑, *HO-1↑, *GLP-1R↑, *HMGB1↓, *RAGE↓, *NF-kB↓, *TGF-β1↓, *PI3K↓, *Akt↓, *GutMicro↑, *SCFAs↑, *Buty↑, *IBI↑, *TJ↑, *Dose↝,
7013- Fuc,    Fucoidan-based nanoparticles for colorectal cancer therapy: Mechanisms and preclinical insights
- Review, CRC, NA
*Inflam↓, *antiOx↑, AntiCan↑, BioAv↑, Apoptosis↑, angioG↓, Imm↝, ChemoSen↑, chemoP↑,
7018- Fuc,    Absorption Study of Mozuku Fucoidan in Japanese Volunteers
- Trial, Nor, NA
*Dose↝, *BioAv↝, *eff↝, *Inflam↓, *AntiThr↑, angioG↓, *AntiViral↑, *AntiTum↑, *antiOx↓, *BioAv↝,
7019- Fuc,    Fucoidan protects hepatocytes from apoptosis and inhibits invasion of hepatocellular carcinoma by up-regulating p42/44 MAPK-dependent NDRG-1/CAP43
- vitro+vivo, HCC, HUH7
TumCI↓, p42↑, p44↑, MAPK↑, TumMeta↓, hepatoP↑, *antiOx↑, *TumCP↓, Vim↓, E-cadherin↓, Fibronectin↓, NDRG1↑, VMP-1↑, TumMeta↓,
7006- Fuc,    Seaweeds in the Oncology Arena: Anti-Cancer Potential of Fucoidan as a Drug—A Review
- Review, Var, NA
*toxicity↓, *AntiViral↑, *antiOx↑, *Imm⇅, AntiCan↑, TumCCA↑, Apoptosis↑, TumMeta↓, angioG↓, antiNeop↑, VEGF↓, MMPs↓, BioAv↑, BioAv↑, ROS⇅, cl‑PARP↑, Casp3↑, Casp7↑, ROS↑, GSH↓, MMP↓, PI3K↓, ERK↓, MAPK↑, TumCP↓, Bax:Bcl2↑, TJ↑, ZO-1↑, OCLN↑, CLDN1↑, IBI↑, GutMicro↑, NK cell↑, STAT3↓, eff↑,
7007- Fuc,    The Therapeutic Potential of the Anticancer Activity of Fucoidan: Current Advances and Hurdles
- Review, Var, NA
TumCCA↑, Apoptosis↑, NK cell↑, chemoP↑, TumCG↓, *Inflam↓, *antiOx↑, *AntiThr↑, *AntiViral↑, angioG↓, ChemoSen↑, ROS↑, GSH↓, mtDam↓, MMP↓, DNMT3B↓, TumCG↓, Dose↝, Dose↝, QoL∅, fatigue∅, Dose↝,
7008- Fuc,    Ten Years of Research on Fucoidan and Cancer: Focus on Its Antiangiogenic and Antimetastatic Effects
- Review, Var, NA
antiOx↑, AntiViral↑, Imm↝, *AntiThr↑, *AntiDiabetic↑, AntiTum↑, TumMeta↑, angioG↓, Hif1a↓, VEGF↓, MMPs↓, EMT↓, N-cadherin↓, E-cadherin↑, TIMP1↑, PI3K↓, Akt↓, mTOR↓, MMP2↓, ChemoSen↑, OS↑, fatigue↓, CD31/PECAM-1↓,
4024- FulvicA,    ANTI-CARCINOGENIC ACTIVITY OF SHILAJIT REGARDING TO APOPTOSIS ASSAY IN CANCER CELLS: A SYSTEMATIC REVIEW OF IN-VITRO STUDIES
- Review, Var, NA
*Inflam↓, *antiOx↑, TumCG↓, tumCV↓, ROS↑, ChemoSen↑, toxicity↝,
4025- FulvicA,    Mumio (Shilajit) as a potential chemotherapeutic for the urinary bladder cancer treatment
- in-vitro, Bladder, T24/HTB-9 - Review, AD, NA
tumCV↓, selectivity↑, TumCCA↑, other↝, *neuroP↑, *memory↑, *tau↓, *other↝, *lipid-P↓, *VitC↑, *antiOx↑,
4026- FulvicA,    Shilajitin Cancer Treatment: Probable Mode of Action
- Review, Var, NA
*Inflam↓, *antiOx↑, Dose↝,
4016- FulvicA,    Shilajit: A Natural Phytocomplex with Potential Procognitive Activity
- Review, AD, NA
*tau↓, *AntiAge↑, *Strength↑, *Dose↝, *BioAv↑, *antiOx↑, *memory↑, *Inflam↓, *cognitive↑, *neuroP↑, *toxicity↝, *toxicity↑,
7035- GA,    Gallic acid attenuates LPS-induced inflammation in Caco-2 cells by suppressing the activation of the NF-κB/MAPK signaling pathway
- in-vitro, IBD, Caco-2
*Inflam↓, *antiOx↑, *CLDN1↓, *OCLN↓, *ZO-1↓, *IL6↓, *IL1β↓, *TNF-α↓, *BAX↓, *BAD↓, *Casp3↓, *Casp8↓, *ROS↓, *SOD↑, *Catalase↑, *GSH↑, *TJ↑, *Apoptosis↓, *NF-kB↓, *MAPK↓,
7042- GA,    Gallic acid reduces cell growth by induction of apoptosis and reduction of IL-8 in HepG2 cells
- in-vitro, Liver, HepG2
*Inflam↓, *AntiTum↑, *antiOx↑, TumCP↓, IL8↓, IL10↑, IL12↑, Apoptosis↑,
7049- GA,    Pharmacological effects of gallic acid in health and diseases: A mechanistic review
- Review, Var, NA
*antiOx↑, *Inflam↓, *antiNeop↑, *cardioP↑, *Bacteria↓, *AST↓, *ALAT↓, *ALP↓, *lipid-P↓, *GSH↑, *Catalase↑, *GPx↑, *GSTs↑, *Urea↓, *creat↓, tumCV↓, TumCCA↑, i-Ca+2↑, CDK1↑, Casp3↑, Casp8↑, Casp9↑, MMP↓, ROS↑, MMPs↓, *GastroP↑, *hepatoP↑, *ROS↓, *AChE↑,
1773- GA,    Impact of Gallic Acid on Gut Health: Focus on the Gut Microbiome, Immune Response, and Mechanisms of Action
- Review, Var, NA
antiOx↑, AntiCan↑, Inflam↓, GutMicro↑, BioAv↝, BioAv↓, BioAv↑, TumMeta↓,
7069- GABA,    United States Pharmacopeia (USP) Safety Review of Gamma-Aminobutyric Acid (GABA)
- Review, Nor, NA
*toxicity↓, *BP↓, *AntiDiabetic↑, *AntiCan↑, *antiOx↑, *Inflam↓, *AntiBio↑, *other↝, *cognitive↑, *GH↑, *Sleep↑, *BioAv↑, *Half-Life↝, *BBB↓, *eff↑,
7066- GamB,    Unravelling the Therapeutic Potential of Gambogic Acid: Deciphering Its Molecular Mechanism of Action and Emerging Role as an Anticancer Xanthone
- Review, Var, NA
angioG↓, TumMeta↓, ChemoSen↑, *cardioP↑, *Inflam↓, *AntiViral↑, *antiOx↑, NF-kB↓, TNF-α↓, COX2/PTGS2↓, iNOS↓, Apoptosis↑, TumAuto↑, TumCP↓, TumCI↓, BioAv↓, ROS↑, MMP↓, SIRT1↓, Akt↓, mTORC1↓, AMPK↑, LRIG1↑, ER Stress↑, Paraptosis↑, Ferroptosis↑, HSP90↓, GSH↓, lipid-P↑, GPx4↓, miR-21↓, PI3K↓, Akt↓, PTEN↑, ASAP2↓, CDK7↓,
7084- GAR,    A unique in vivo pharmacokinetic profile, in vitro metabolic stability and hepatic first-pass metabolism of garcinol, a promising novel anticancer phytoconstituent, by liquid chromatography–mass spectrometry
- in-vivo, Nor, NA
*BioAv↝, *Dose↝, *Inflam↓, *antiOx↑, *chemoPv↑, Wnt↓, β-catenin/ZEB1↓, ERK↓, PI3K↓, Akt↓, NF-kB↓, STAT3↓, TumCP↓, antiNeop↑, ChemoSen↑, chemoP↑,
7090- GAR,    Garcinol
AChE↓, BChE↓, *Inflam↓, *5LO↓, *PGE2↓, *antiOx↑, FAK↓, DNAdam↑, MMP↓, Casp↑, NF-kB↓, HATs↓, *toxicity↓,
7091- GAR,    Garcinol-A Natural Histone Acetyltransferase Inhibitor and New Anti-Cancer Epigenetic Drug
- Review, Var, NA
antiOx↑, Inflam↓, HATs↓, p300↓, CBP↓, PCAF↓, cycD1/CCND1↓, STAT↓, PI3K↓, Akt↓, TumCP↓, TumCI↓, TumMeta↓, TumCCA↑, CDK2↓, CDK4↓,
7092- GAR,    Garcinol and Its Role in Chronic Diseases
- Review, Var, NA
antiOx↑, Inflam↓, AntiCan↑, NF-kB↓, STAT3↓, antiNeop↑, 5LO↓, eff↑, HATs↓, p300↓, PCAF↓, miR-200c↑, NOTCH1↓, CSCs↓, COX2/PTGS2↓, cycD1/CCND1↓, VEGF↓, PI3K↓, Akt↓, Wnt↑, β-catenin/ZEB1↓, ROS↑, CHOP/DDIT3↑, Bax:Bcl2↑, Casp8↑, FAK↓, *neuroP↑, PCNA↓, *GSTs↑,
7234- GBE,    Ginkgo Biloba Extract Ameliorates Oxidative Phosphorylation Performance and Rescues Aβ-Induced Failure
- in-vitro, Nor, NA
*antiOx↑, *ROS↓, *OXPHOS↑, *OCR↑, *compI↓,
7205- GBE,    Exploring the multifaceted role of ginkgolides and bilobalide from Ginkgo biloba in mitigating metabolic disorders
- Review, AD, NA
*antiOx↑, *Inflam↓, *neuroP↑, *ROS↓, *cardioP↑, *Obesity↓, *BioAv↓,
7206- GBE,  EGb 761,    Ginkgo biloba: A Leaf of Hope in the Fight against Alzheimer's Dementia: Clinical Trial Systematic Review
- Review, AD, NA
*Dose↝, *Inflam↓, *antiOx↑, *neuroP↑, *cognitive↑,
7212- GBE,    The Use of Ginkgo Biloba L. as a Neuroprotective Agent in the Alzheimer’s Disease
- Review, AD, NA
*antiOx↑, *ROS↓, *mitResp↑, *Casp9↓, *Casp3↓, *Apoptosis↓, *ATP↑, *neuroP↑, *IL1β↓, *IL6↓, *TNF-α↓, *PGE2↓, *memory↑, *cognitive↑, *BloodF↑, *lipid-P↓, *Aβ↓, *MAOA↓, *DA↑, *Dose↝, *toxicity↓,
1189- GBE,    New insight into the mechanisms of Ginkgo biloba leaves in the treatment of cancer
- Review, NA, NA
Apoptosis↑, TumCP↓, TumCI↓, TumCMig↓, Inflam↓, antiOx↑, angioG↓,
3723- GBE,    Can We Use Ginkgo biloba Extract to Treat Alzheimer’s Disease? Lessons from Preclinical and Clinical Studies
- Review, AD, NA
*memory↑, *antiOx↑, *Casp3↓, *APP↓, *AChE↓, *Aβ↓, *5HT↑, *SOD↓, *MDA↓, *NO↓, *GSH↑, *Bcl-2↑, *BAX↑, *TNF-α↓, *IL1β↑, *iNOS↓, *IL10↓, *p‑tau↓, *ROS↓, *MAOB↓, *cognitive↑, *neuroP↑, *Apoptosis↓,
7133- Ge-132,    Organogermanium, Ge-132, promotes the clearance of senescent red blood cells via macrophage-mediated phagocyte activation
- in-vitro, Nor, RAW264.7
*RBC↑, *antiOx↑,
7103- GEN,    A Comprehensive Review of Genistein's Effects in Preclinical Models of Cervical Cancer
- Review, Cerv, NA
TumCP↓, Apoptosis↑, RadioS↑, ChemoSen↑, *antiOx↑, *Inflam↓, *Bacteria↓, *AntiViral↑, *AntiDiabetic↑, *neuroP↑, AntiCan↑, TumCG↓, TumCI↓, TumCCA↑, cl‑PARP↑, selectivity↑, CycB/CCNB1↓, CDK1↓, p‑cDC2↓, p‑ERK↓, p‑p38↑, p‑JNK↑, MMP9↓, TIMP1↑, BioAv↓, BioAv↑, Half-Life↑,
7102- GEN,    Genistein: An Integrative Overview of Its Mode of Action, Pharmacological Properties, and Health Benefits
- Review, Var, NA
*antiOx↑, *Inflam↓, *Bacteria↓, *AntiViral↑, *Dose↝, *AntiDiabetic↑, angioG↑, Apoptosis↑, tumCV↓, MyD88↑, Beclin-1↑, LC3II↑, TLR4↑, TumAuto↑, mTOR↓, p62↓, TumCCA↑, TumCP↓, Akt↑, P53↑, DNMT3B↓, MEK↓, hTERT/TERT↓, VEGF↓, NF-kB↓, IAP1↓, MDR1↓, p‑Akt↓, eff↑, ChemoSen↑,
6562- Ger,    Potential Effects of Geraniol on Cancer and Inflammation-Related Diseases: A Review of the Recent Research Findings
- Review, Var, NA - Review, AD, NA
*Inflam↓, *AntiCan↑, *AntiBio↑, *antiOx↑, *neuroP↑, ROS↓, Apoptosis↑, TumCCA↑, P53↝, STAT3↓, Casp↝, *Catalase↑, *GSTs↑, *GPx↑, *AChE↓, *GSH↑, *SOD↑, *TBARS↓, *NO↓, *XO↓, *memory↑, *IL1β↓, *iNOS↓, *NF-kB↓, *COX2/PTGS2↓, *NRF2↑, *HO-1↑, *survivin↓, TumCP↓, TumCMig↓, TumCG↑, selectivity↑, TumMeta↓, angioG↓, Hif1a↓, Beclin-1↓,
6567- Ger,    Geraniin inhibits proliferation and induces apoptosis through inhibition of phosphatidylinositol 3-kinase/Akt pathway in human colorectal cancer in vitro and in vivo
- vitro+vivo, CRC, SW480 - in-vitro, CRC, HT29
AntiTum↑, *Inflam↓, *antiOx↓, TumCP↓, BAX↑, Casp3↑, Casp9↑, Bcl-2↓, TumCMig↓, TumCI↓, MMP2↓, MMP9↓, p‑PI3K↓, p‑Akt↓, Dose↝, TumCG↓,
6571- Ger,    Unlocking the therapeutic potential of Geraniol: an alternative perspective for metabolic disease management
- Review, Obesity, NA
*lipidLev↓, *antiOx↓, Inflam↓, *ROS↓, *BioAv↑, *AntiDiabetic↑, *Obesity↓,
7217- GGB,    Role of Ginkgolides in the Inflammatory Immune Response of Neurological Diseases: A Review of Current Literatures
- Review, AD, NA
*eff↑, *AntiAg↑, *Apoptosis↓, *antiOx↑, *Inflam↓, *MAPK↓, *NF-kB↓, *PAF↓, *TLR1↓, *MyD88↓, *BDNF↑, *ROS↓, *PARP↓, *Cyt‑c↓,
7141- GI,    Synthesis of New Shogaol Analogues as NRF2 Activators and Evaluation of Their Anti-Inflammatory Activity, Modes of Action and Metabolic Stability
- Study, Nor, BV2
*eff↑, *eff↓, *NRF2↑, *Inflam↓, *eff↑, *antiOx↑, *neuroP↑, *COX2/PTGS2↓, *NF-kB↓, *eff↓, *BioAv↝, *BioAv↑,
7142- GI,    Phase II study of the Effects of Ginger Root Extract on Eicosanoids in Colon Mucosa in People at Normal Risk for Colorectal Cancer
- Trial, Nor, NA
COX2/PTGS2↓, *PGE2↓, *5-HETE↓, *12-HETE↓, *Eic↓, *AntiCan↑, *antiOx↑, *Inflam↓, 5LO↓, eff↝,
7140- GI,    Benefits of Ginger and Its Constituent 6-Shogaol in Inhibiting Inflammatory Processes
- Review, Var, NA
*Dose↝, *Inflam↓, *COX2/PTGS2↓, *iNOS↓, *NF-kB↓, *MAPK?, *HO-1↑, *PGE2↓, *TNF-α↓, *IL6↓, *IL1β↓, *IFN-γ↓, *MCP1/CCL2↓, *MIP2↓, *RANTES↓, *MPO↓, *NO↓, *Stroke↓, *BrainVol↑, *MDA↓, *ROS↓, *GSH↑, *NRF2↑, *antiOx↑, NLRP3↓, HDAC1↓,
7135- GI,    Examination of the Pharmacokinetics of Active Ingredients of Ginger in Humans
- Trial, Nor, NA
*Dose↝, *Half-Life↝, *antiOx↑, *Inflam↓, *AntiTum↑, *Half-Life↓,
6771- GI,    A glimpse on influences of ginger and its derivatives as a feed additive in finfish farming: A mini-review
- Review, Nor, NA
*AntiBio↓, *Imm↑, *Inflam↓, *antiOx↑, *SOD↓, *Catalase↓, *GSH↓,
4247- GI,    6-Shogaol from Dried Ginger Protects against Intestinal Ischemia/Reperfusion by Inhibiting Cell Apoptosis via the BDNF/TrkB/PI3K/AKT Pathway
- vitro+vivo, NA, NA
*BDNF↑, *TrkB↑, *PI3K↑, *Akt↑, *Apoptosis↓, *Inflam↓, *antiOx↑,
2464- GI,    The Effect of Ginger (Zingiber officinale) on Platelet Aggregation: A Systematic Literature Review
- Review, Nor, NA
*Inflam↓, *antiOx↑, *LDL↓, *AntiAg↑, *AntiAg∅,
7251- Gink,    Ginkgetin: A Promising Multitarget Agent for Diverse Diseases
- Review, Var, NA
*Inflam↓, *antiOx↓, AntiCan↑, *neuroP↑, *cardioP↑, *Bacteria↓, *ROS↓, *lipid-P↓, *NRF2↓, *Keap1↓, *NF-kB↓, *MAPK↓, MMP2↓, M2 MC↓, JAK2↓, STAT3↓, TumCP↓, Casp↑, ChemoSen↑, *BMD↑, *Aβ↓, *Stroke↓, *BioAv↓,

Showing Research Papers: 401 to 450 of 868
Prev Page 9 of 18 Next

* indicates research on normal cells as opposed to diseased cells
Total Research Paper Matches: 868

Pathway results for Effect on Cancer / Diseased Cells:


NA, unassigned(tgid=0) ⓘ

ASAP2↓, 1,   CDK7↓, 1,   LRIG1↑, 1,   VMP-1↑, 1,  

Redox & Oxidative Stress(tgid=1) ⓘ

antiOx↑, 7,   Ferroptosis↑, 1,   GPx4↓, 1,   GSH↓, 3,   lipid-P↑, 1,   ROS↓, 1,   ROS↑, 6,   ROS⇅, 1,  

Mitochondria & Bioenergetics(tgid=3) ⓘ

MEK↓, 1,   MMP↓, 5,   mtDam↓, 1,   p42↑, 1,   XIAP↓, 1,  

Core Metabolism/Glycolysis(tgid=4) ⓘ

AMPK↑, 2,   cMyc↓, 1,   Glycolysis↓, 1,   HK2↓, 1,   PKM2↓, 1,   PKM2:PKM1↓, 1,   SIRT1↓, 1,   Warburg↓, 1,  

Cell Death(tgid=5) ⓘ

Akt↓, 8,   Akt↑, 1,   p‑Akt↓, 3,   Apoptosis↑, 9,   BAX↑, 1,   Bax:Bcl2↑, 2,   Bcl-2↓, 1,   Casp↑, 2,   Casp↝, 1,   Casp3↑, 3,   Casp7↑, 1,   Casp8↑, 2,   Casp9↑, 2,   CBP↓, 1,   Ferroptosis↑, 1,   hTERT/TERT↓, 1,   IAP1↓, 1,   iNOS↓, 1,   p‑JNK↑, 1,   MAPK↑, 2,   p‑p38↑, 1,   Paraptosis↑, 1,  

Transcription & Epigenetics(tgid=7) ⓘ

HATs↓, 3,   miR-21↓, 1,   other↝, 1,   PCAF↓, 2,   tumCV↓, 5,  

Protein Folding & ER Stress(tgid=8) ⓘ

CHOP/DDIT3↑, 1,   ER Stress↑, 1,   HSP90↓, 1,  

Autophagy & Lysosomes(tgid=9) ⓘ

Beclin-1↓, 1,   Beclin-1↑, 1,   LC3II↑, 1,   p62↓, 1,   TumAuto↑, 2,  

DNA Damage & Repair(tgid=10) ⓘ

DNAdam↑, 1,   DNMT3B↓, 2,   P53↑, 1,   P53↝, 1,   cl‑PARP↑, 2,   PCNA↓, 1,  

Cell Cycle & Senescence(tgid=11) ⓘ

CDK1↓, 1,   CDK1↑, 1,   CDK2↓, 2,   CDK4↓, 2,   CycB/CCNB1↓, 1,   cycD1/CCND1↓, 4,   cycE/CCNE↓, 1,   Securin↓, 1,   TumCCA↑, 11,  

Proliferation, Differentiation & Cell State(tgid=12) ⓘ

p‑cDC2↓, 1,   CSCs↓, 1,   EMT↓, 1,   ERK↓, 2,   p‑ERK↓, 1,   HDAC1↓, 1,   mTOR↓, 4,   mTORC1↓, 1,   NOTCH1↓, 1,   p300↓, 2,   PI3K↓, 8,   p‑PI3K↓, 1,   PTEN↑, 2,   STAT↓, 1,   STAT3↓, 5,   TCF↓, 1,   TumCG↓, 7,   TumCG↑, 1,   Wnt↓, 2,   Wnt↑, 1,  

Migration(tgid=13) ⓘ

5LO↓, 2,   i-Ca+2↑, 1,   CD31/PECAM-1↓, 1,   CLDN1↑, 1,   E-cadherin↓, 1,   E-cadherin↑, 1,   FAK↓, 2,   Fibronectin↓, 1,   miR-200c↑, 1,   MMP1↓, 1,   MMP2↓, 3,   MMP7↓, 1,   MMP9↓, 2,   MMPs↓, 4,   N-cadherin↓, 1,   p44↑, 1,   TIMP1↑, 2,   TJ↑, 1,   TumCI↓, 7,   TumCMig↓, 4,   TumCP↓, 12,   TumMeta↓, 7,   TumMeta↑, 1,   uPA↓, 1,   Vim↓, 1,   ZO-1↑, 1,   β-catenin/ZEB1↓, 4,  

Angiogenesis & Vasculature(tgid=14) ⓘ

angioG↓, 11,   angioG↑, 1,   EGFR↓, 1,   Hif1a↓, 3,   VEGF↓, 4,  

Barriers & Transport(tgid=15) ⓘ

GLUT1↓, 1,   IBI↑, 1,   OCLN↑, 1,  

Immune & Inflammatory Signaling(tgid=16) ⓘ

COX2/PTGS2↓, 4,   IL10↑, 1,   IL12↑, 1,   IL8↓, 1,   Imm↝, 2,   Inflam↓, 6,   JAK2↓, 1,   M2 MC↓, 1,   MyD88↑, 1,   NF-kB↓, 6,   NK cell↑, 2,   PGE2↓, 1,   PSA↓, 2,   TLR4↑, 1,   TNF-α↓, 1,  

Synaptic & Neurotransmission(tgid=18) ⓘ

AChE↓, 1,   BChE↓, 1,  

Protein Aggregation(tgid=19) ⓘ

NLRP3↓, 1,  

Drug Metabolism & Resistance(tgid=21) ⓘ

BioAv↓, 3,   BioAv↑, 5,   BioAv↝, 1,   ChemoSen↑, 9,   Dose↝, 5,   eff↑, 4,   eff↝, 1,   Half-Life↑, 1,   MDR1↓, 1,   RadioS↑, 3,   selectivity↑, 3,  

Clinical Biomarkers(tgid=22) ⓘ

EGFR↓, 1,   GutMicro↑, 2,   hTERT/TERT↓, 1,   PSA↓, 2,  

Functional Outcomes(tgid=23) ⓘ

AntiCan↑, 9,   antiNeop↑, 3,   AntiTum↑, 2,   chemoP↑, 3,   fatigue↓, 1,   fatigue∅, 1,   hepatoP↑, 1,   NDRG1↑, 1,   OS↑, 1,   QoL∅, 1,   Risk↓, 1,   toxicity↝, 1,  

Infection & Microbiome(tgid=24) ⓘ

AntiViral↑, 2,  
Total Targets: 176

Pathway results for Effect on Normal Cells:


NA, unassigned(tgid=0) ⓘ

12-HETE↓, 1,   5-HETE↓, 1,   AntiBio↓, 1,   AntiBio↑, 2,   Buty↑, 1,   DA↑, 1,   diuretic↑, 1,   Eic↓, 1,   GLP-1R↑, 1,   PAF↓, 1,   RBC↑, 1,   SCFAs↑, 1,   Stroke↓, 3,  

Redox & Oxidative Stress(tgid=1) ⓘ

antiOx↓, 4,   antiOx↑, 39,   Catalase↓, 1,   Catalase↑, 5,   compI↓, 1,   GPx↑, 3,   GSH↓, 1,   GSH↑, 8,   GSTs↑, 3,   HO-1↑, 5,   Keap1↓, 1,   lipid-P↓, 6,   MDA↓, 3,   MPO↓, 1,   NRF2↓, 1,   NRF2↑, 6,   OXPHOS↑, 1,   ROS↓, 14,   SOD↓, 2,   SOD↑, 4,   TBARS↓, 1,   uricA↓, 1,   VitC↑, 1,  

Mitochondria & Bioenergetics(tgid=3) ⓘ

ATP↑, 1,   mitResp↑, 1,   OCR↑, 1,  

Core Metabolism/Glycolysis(tgid=4) ⓘ

ALAT↓, 1,   p‑CREB↑, 1,   LDL↓, 1,   lipidLev↓, 1,   SIRT1↑, 1,  

Cell Death(tgid=5) ⓘ

Akt↓, 1,   Akt↑, 1,   Apoptosis↓, 5,   BAD↓, 1,   BAX↓, 1,   BAX↑, 1,   Bcl-2↑, 1,   Casp3↓, 3,   Casp8↓, 1,   Casp9↓, 1,   Cyt‑c↓, 1,   iNOS↓, 3,   JNK↓, 1,   MAPK?, 1,   MAPK↓, 4,   survivin↓, 1,  

Transcription & Epigenetics(tgid=7) ⓘ

AntiThr↑, 4,   other↝, 2,  

DNA Damage & Repair(tgid=10) ⓘ

DNAdam↓, 1,   PARP↓, 1,  

Proliferation, Differentiation & Cell State(tgid=12) ⓘ

ERK↑, 2,   GH↑, 1,   PI3K↓, 2,   PI3K↑, 1,   STAT3↓, 1,  

Migration(tgid=13) ⓘ

5LO↓, 4,   AntiAg↑, 3,   AntiAg∅, 1,   APP↓, 1,   CLDN1↓, 1,   COL1↓, 1,   Fibrosis↓, 1,   MMP9↓, 1,   RAGE↓, 1,   TGF-β1↓, 1,   TJ↑, 2,   TumCP↓, 1,   ZO-1↓, 1,   α-SMA↓, 1,  

Angiogenesis & Vasculature(tgid=14) ⓘ

NO↓, 3,  

Barriers & Transport(tgid=15) ⓘ

BBB↓, 1,   GastroP↑, 1,   IBI↑, 1,   OCLN↓, 1,  

Immune & Inflammatory Signaling(tgid=16) ⓘ

COX2/PTGS2↓, 4,   HMGB1↓, 1,   IFN-γ↓, 1,   IL10↓, 1,   IL1β↓, 4,   IL1β↑, 1,   IL6↓, 3,   Imm↑, 1,   Imm⇅, 2,   Inflam↓, 34,   JAK2↓, 1,   MCP1/CCL2↓, 1,   MIP2↓, 1,   MyD88↓, 1,   NF-kB↓, 10,   PGE2↓, 4,   RANTES↓, 1,   TLR1↓, 1,   TNF-α↓, 5,  

Synaptic & Neurotransmission(tgid=18) ⓘ

5HT↑, 1,   AChE↓, 4,   AChE↑, 1,   BDNF↑, 2,   BrainVol↑, 1,   MAOA↓, 1,   tau↓, 2,   p‑tau↓, 1,   TrkB↑, 1,  

Protein Aggregation(tgid=19) ⓘ

Aβ↓, 4,   BACE/β-secretase↓, 1,   MAOB↓, 1,   NLRP3↓, 1,   XO↓, 2,  

Drug Metabolism & Resistance(tgid=21) ⓘ

BioAv↓, 4,   BioAv↑, 5,   BioAv↝, 4,   Dose↝, 9,   eff↓, 2,   eff↑, 4,   eff↝, 1,   Half-Life↓, 1,   Half-Life↝, 2,  

Clinical Biomarkers(tgid=22) ⓘ

ALAT↓, 1,   ALP↓, 1,   AST↓, 1,   BloodF↑, 2,   BMD↑, 1,   BP↓, 2,   creat↓, 1,   GutMicro↑, 1,   IL6↓, 3,   RAGE↓, 1,   Urea↓, 1,  

Functional Outcomes(tgid=23) ⓘ

AntiAge↑, 3,   AntiCan↑, 3,   AntiDiabetic↑, 7,   antiNeop↑, 1,   AntiTum↑, 3,   cardioP↑, 7,   chemoPv↑, 2,   cognitive↑, 6,   hepatoP↑, 1,   memory↑, 7,   neuroP↑, 14,   Obesity↓, 2,   RenoP↑, 1,   Sleep↑, 1,   Strength↑, 1,   toxicity↓, 4,   toxicity↑, 1,   toxicity↝, 1,  

Infection & Microbiome(tgid=24) ⓘ

AntiFungal↑, 2,   AntiViral↑, 7,   Bacteria↓, 5,  
Total Targets: 162

Scientific Paper Hit Count for: antiOx, anti-oxidant activities
37 Lycopene
31 Curcumin
28 Thymoquinone
25 Resveratrol
25 Alpha-Lipoic-Acid
25 Hydrogen Gas
24 Selenium NanoParticles
24 Quercetin
20 Silymarin (Milk Thistle) silibinin
19 Rosmarinic acid
17 Ferulic acid
16 Astaxanthin
16 Chlorogenic acid
15 Silver-NanoParticles
15 EGCG (Epigallocatechin Gallate)
14 Eugenol
14 Honokiol
13 Berberine
13 Carvacrol
12 Baicalein
12 Propolis -bee glue
12 Fisetin
11 Allicin (mainly Garlic)
10 Coenzyme Q10
10 Vitamin C (Ascorbic Acid)
10 Luteolin
9 Crocetin
9 Dandelion Root
9 Magnetic Fields
9 Moringa oleifera
8 Melatonin
8 Selenium
8 chitosan
8 Sulforaphane (mainly Broccoli)
8 Emodin
8 Urolithin
7 Radiotherapy/Radiation
7 Apigenin (mainly Parsley)
7 α-Bisabolol / Chamomile oil
7 Cinnamon
7 Chemotherapy
7 Fucoidan
7 Ginger/6-Shogaol/Gingerol
7 Magnolol
6 Phyllanthus emblica/Emblica officinalis/Amla / Indian Gooseberry
6 Ashwagandha(Withaferin A)
6 Betulinic acid
6 Boron
6 Caffeic acid
6 Capsaicin
6 Chrysin
6 Cichoric acid / Chicoric acid
6 Hydroxycinnamic-acid
6 Ellagic acid
6 Ginkgo biloba
6 Isoliquiritigenin
6 Piperine
5 doxorubicin
5 Beta-Caryophyllene
5 Thymol-Thymus vulgaris
5 Carnosine
5 Centella asiatica / Gotu kola → asiaticoside
5 Vitamin E
5 Carvone
5 Ginkgo biloba-EGb 761
5 Hibiscus sabdariffa
5 HydroxyTyrosol
5 Pterostilbene
5 Selenite (Sodium)
4 Cisplatin
4 beta-carotene(VitA)
4 Bacopa monnieri
4 Caffeic Acid Phenethyl Ester (CAPE)
4 Date Fruit Extract
4 D-limonene
4 flavonoids
4 Shilajit/Fulvic Acid
4 Gallic acid
4 Garcinol
4 Hyperoside
4 iodine
4 IP6 (Inositol 1,2,3,4,5,6-hexakisphosphate)
4 Mung Bean Sprouts
4 Shikonin
3 Anthocyanins
3 Cynara scolymus/Globe Artichoke/Artichoke Extract
3 Ascorbyl Palmitate
3 Chyawanprash
3 Vitamin K2
3 Carica papaya leaf extract
3 Cucurbitacin
3 Dipyridamole
3 Geraniol
3 Inositol
3 isoquercitrin
3 Lecithin
3 Naringin
3 Nimbolide
3 Rutin
3 Salvia officinalis
3 Taurine
3 Ursolic acid
2 1,8-Cineole
2 5-fluorouracil
2 Anethole/trans-Anethole
2 Fennel Oil/Foeniculum vulgare
2 Aromatherapy
2 Vitamin B6,pyridoxine
2 Chocolate
2 Echinacea
2 Eurycomanone
2 Genistein (soy isoflavone)
2 Ginkgetin
2 High-Ozonide Oil
2 Huperzine A/Huperzia serrata
2 Isobavachalcone
2 isoflavones
2 Juglone
2 Methylene blue
2 Phenylbutyrate
2 Phenethyl isothiocyanate
2 Propyl gallate
2 Rauwolfia serpentina/Indian Snakeroot
2 α-Santalol/Sandalwood oil
2 Shankhpushpi
2 Vitamin B1/Thiamine
2 Vitamin B12
2 Folic Acid, Vit B9
2 Vitamin D3
1 Astragalus
1 Citric Acid
1 Ajoene (compound of Garlic)
1 alpha Linolenic acid
1 DTS(dibenzyl trisulphide) from Anamu
1 Artemisinin
1 Aloe anthraquinones
1 beta-glucans
1 Baicalin
1 Biochanin A
1 Cannabidiol
1 Boswellia (frankincense)
1 Bruteridin(bergamot juice)
1 Carnosic acid
1 Celastrol
1 Chlorophyllin
1 Choline
1 methotrexate
1 Copper and Cu NanoParticles
1 Deguelin
1 Dihydrocaffeic Acid
1 diet Fermented Foods
1 diet Methionine-Restricted Diet
1 Aspirin
1 eicosapentaenoic acid
1 Fenbendazole
1 Gamma-aminobutyric acid
1 Gambogic Acid
1 Germanium Organic/Ge-132 / propagermanium (organogermanium)
1 Ginkgolide B
1 Germacranolide sesquiterpene lactone
1 hydrogen sulfide
1 Helleborus niger extracts – Christmas Rose
1 Oleuropein
1 Indole-3-carbinol
1 Butein
1 Scopoletin
1 Kaempferol
1 Lutein
1 Methyl salicylate / Sweet Birch oil
1 Magnetic Field Rotating
1 Methylsulfonylmethane
1 N-Acetyl-Cysteine
1 nicotinamide adenine dinucleotide
1 Neem
1 Oleocanthal
1 Oregano
1 Phenolic Acids
1 Polyphenols
1 Phosphatidylserine
1 Psoralidin
1 Perilla
1 Gold NanoParticles
1 Sinapic acid
1 Sulfasalazine
1 Sesame seeds and Oil
1 Iron
1 Spermidine
1 Terpinen-4-ol / Tea Tree Oil
1 cetuximab
1 Ginseng
1 Aflavin-3,3′-digallate
1 Vanillic Acid
1 Dichloroacetate
1 probiotics
1 Zinc
Query results interpretion may depend on "conditions" listed in the research papers.
Such Conditions may include : 
  -low or high Dose
  -format for product, such as nano of lipid formations
  -different cell line effects
  -synergies with other products 
  -if effect was for normal or cancerous cells

Filter Conditions: Pro/AntiFlg:%  IllCat:%  CanType:%  Cells:%  prod#:%  Target#:1103  State#:%  Dir#:%
  wNotes=0  sortOrder:rid,rpid

 

Home Page