Dose Cancer Research Results

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Drug dosage vs efficacy, and actual dosage number of research papers.
Scientific Papers found: Click to Expand⟱
1663- PBG,    Propolis and Their Active Constituents for Chronic Diseases
- Review, Var, NA
NF-kB↓, Casp↓, Fas↓, DNAdam↑, Casp3↑, P53↝, MMP↝, ROS↑, mtDam↑, Dose?, angioG↓, TumCP↓, TumCMig↓, BAX↑, selectivity↑, MMP↓, LDH↓, IL6↓, IL1β↓, TNF-α↓,
1665- PBG,    Evidence on the Health Benefits of Supplemental Propolis
- Review, Nor, NA
*antiOx↑, *Inflam↓, *toxicity↑, *Dose?,
1666- PBG,    Molecular and Cellular Mechanisms of Propolis and Its Polyphenolic Compounds against Cancer
- Review, Var, NA
ChemoSen↑, TumCCA↑, TumCP↓, Apoptosis↑, antiOx↓, ROS↑, COX2↑, ER(estro)↓, cycA1/CCNA1↓, CycB/CCNB1↓, CDK2↓, P21↑, p27↑, hTERT/TERT↓, HDAC↓, ROS⇅, Dose?, ROS↓, ROS↑, DNAdam↑, ChemoSen↑, LOX1↓, lipid-P↓, NO↑, Igs↑, NK cell↑, MMPs↓, VEGF↓, Hif1a↓, GLUT1↓, HK2↓, selectivity↑, RadioS↑, GlucoseCon↓, lactateProd↓, eff↓, *BioAv↓,
1668- PBG,    Propolis: A Detailed Insight of Its Anticancer Molecular Mechanisms
- Review, Var, NA
antiOx↑, Inflam↓, AntiCan↑, TumCP↓, Apoptosis↑, eff↝, MMPs↓, TNF-α↓, iNOS↓, COX2↓, IL1β↑, *BioAv↓, BAX↑, Casp3↑, Cyt‑c↑, Bcl-2↓, eff↑, selectivity↑, P53↑, ROS↑, Casp↑, eff↑, ERK↓, Dose∅, TRAIL↑, NF-kB↑, ROS↑, Dose↑, MMP↓, DNAdam↑, TumAuto↑, LC3II↑, p62↓, EGF↓, Hif1a↓, VEGF↓, TLR4↓, GSK‐3β↓, NF-kB↓, Telomerase↓, ChemoSen↑, ChemoSideEff↓,
2382- PBG,    Integration with Transcriptomic and Metabolomic Analyses Reveals the In Vitro Cytotoxic Mechanisms of Chinese Poplar Propolis by Triggering the Glucose Metabolism in Human Hepatocellular Carcinoma Cells
- in-vitro, HCC, HepG2
TumCP↓, Glycolysis↓, GlucoseCon↓, lactateProd↓, GLUT1↓, GLUT2↓, LDHA↓, HK2↓, PKM2↓, PFK↓, Dose↝,
4954- PEITC,    Selective killing of oncogenically transformed cells through a ROS-mediated mechanism by β-phenylethyl isothiocyanate
- vitro+vivo, Ovarian, SKOV3
ROS↑, GSH↓, selectivity↑, mtDam↑, TumCD↑, OS↑, eff↑, *toxicity↓, H2O2↑, NO↑, eff↓, GPx↓, Dose↝, eff↑,
4963- PEITC,    Doses_of_b_-_Phenylethyl_isothiocyanate_PEITC_Induce_Cell_Cycle_Arrest_and_Retard_Growth_of_p53_Mutated_Oral_Cancer_In_Vitro_and_In_Vivo">Sensory Acceptable Equivalent Doses of β - Phenylethyl isothiocyanate (PEITC) Induce Cell Cycle Arrest and Retard Growth of p53 Mutated Oral Cancer In Vitro and In Vivo
- vitro+vivo, Oral, CAL27 - vitro+vivo, Oral, FaDu - vitro+vivo, Oral, SCC4 - vitro+vivo, Oral, SCC9
Dose↝, selectivity↑, TumCG↓, OS↑, ROS↑, P53↑, P21↑, TumCCA↑, Ki-67↓,
4922- PEITC,    Phenethyl Isothiocyanate: A comprehensive review of anti-cancer mechanisms
- Review, Var, NA
Risk↓, AntiCan↑, TumCP↓, TumMeta↓, ChemoSen↑, *BioAv↑, *other↝, *Dose↝, Dose↓, *BioAv↑, *Dose↝, *Half-Life↝, *toxicity↝, GSH↓, ROS↑, CYP1A1↑, CYP1A2↑, P450↓, CYP2E1↑, CYP3A4↓, CYP2A3/CYP2A6↓, *ROS↓, *GPx1↑, *SOD1↑, *SOD2↑, Akt↓, EGFR↓, HER2/EBBR2↓, P53↑, Telomerase↓, selectivity↑, MMP↓, Cyt‑c↑, Apoptosis↑, DR4↑, Fas↑, XIAP↓, survivin↓, TumAuto↑, Hif1a↓, angioG↓, MMPs↓, ERK↓, NF-kB↓, EMT↓, TumCI↓, TumCMig↓, Glycolysis↓, ATP↓, selectivity↑, *antiOx↑, Dose↝, other↝, OCR↓, GSH↓, ITGB1↓, ITGB6↓, ChemoSen↑,
4924- PEITC,    Nutri-PEITC Jelly Significantly Improves Progression-Free Survival and Quality of Life in Patients with Advanced Oral and Oropharyngeal Cancer: A Blinded Randomized Placebo-Controlled Trial
- Trial, Oral, NA
QoL↑, P53↑, OS↑, Cyt‑c↝, other↝, ROS↑, selectivity↑, P21↑, TumCCA↑, Dose↝, BioAv↑, Weight↑, chemoP↑,
4925- PEITC,    PEITC triggers multiple forms of cell death by GSH-iron-ROS regulation in K7M2 murine osteosarcoma cells
- in-vitro, OS, NA
tumCV↓, TumCP↓, TumCCA↑, GSH↓, ROS↑, Ferroptosis↑, Apoptosis↑, TumAuto↑, MAPK↑, TumCG↓, Dose⇅,
4938- PEITC,    Clinical Trial of 2-Phenethyl Isothiocyanate as an Inhibitor of Metabolic Activation of a Tobacco-Specific Lung Carcinogen in Cigarette Smokers
- Trial, Nor, NA
*Risk↑, *P450↓, *BioAv↑, *BioAv↑, *BioAv↑, *Dose↝, Dose↝,
1768- PG,    Propyl gallate reduces the growth of lung cancer cells through caspase‑dependent apoptosis and G1 phase arrest of the cell cycle
- in-vitro, Lung, Calu-6 - in-vitro, Lung, A549
TumCG↓, TumCCA↑, Dose∅, Bcl-2↓, cl‑PARP↑, MMP↓, Casp3↑, Casp8↑,
1774- PG,    Geno- and cytotoxicity of propyl gallate food additive
- in-vitro, Lung, A549
TumCG↓, Dose∅, DNAdam↑,
1764- PG,  Cu,    DNA strand break induction and enhanced cytotoxicity of propyl gallate in the presence of copper(II)
- in-vitro, Nor, GM05757
*DNAdam↑, *ROS↑, *Dose∅, *DNAdam∅,
1765- PG,    Enhanced cell death effects of MAP kinase inhibitors in propyl gallate-treated lung cancer cells are related to increased ROS levels and GSH depletion
- in-vitro, Lung, A549 - in-vitro, Lung, Calu-6
TumCD↑, MMP↓, ROS↑, GSH↓, Dose∅, eff↑,
1939- PL,    Piperlongumine selectively kills hepatocellular carcinoma cells and preferentially inhibits their invasion via ROS-ER-MAPKs-CHOP
- in-vitro, HCC, HepG2 - in-vitro, HCC, HUH7 - in-vivo, NA, NA
TumCMig↓, TumCI↓, ER Stress↑, selectivity↑, tumCV↓, ROS↑, GSH↓, eff↓, Ca+2↑, MAPK↑, CHOP↑, Dose↝,
2968- PL,  Chit,    Preparation of piperlongumine-loaded chitosan nanoparticles for safe and efficient cancer therapy
- in-vitro, GC, AGS
eff↑, Dose↝, ROS↑, BioAv↑,
2963- PL,    Piperlongumine activates Sirtuin1 and improves cognitive function in a murine model of Alzheimer’s disease
- in-vitro, AD, HEK293
*SIRT1↑, *cognitive↑, *Aβ↓, *Inflam↓, *neuroP↑, memory↑, Dose↓, NAD↑,
5630- ProBio,  Bif,    EFFICACY OF PROBIOTICS IN PREVENTING CHEMOTHERAPY-INDUCED DIARRHEA IN GASTROINTESTINAL CANCER PATIENTS
- Trial, GC, NA
Dose↝, Diar⇅,
5624- ProBio,  Bif,    A randomized double-blind placebo-controlled trial of probiotics in post-surgical colorectal cancer
- Trial, Testi, NA
Dose↝, TNF-α↓, IL6↓, IL10↓, IL12↓, IL22↓, toxicity↓,
3916- PS,    The effect of soybean-derived phosphatidylserine on cognitive performance in elderly with subjective memory complaints: a pilot study
- Human, AD, NA
*memory↑, *cognitive↑, *BP↓, *Dose↝, *eff↑,
3931- PTS,    Pterostilbene Protects against Osteoarthritis through NLRP3 Inflammasome Inactivation and Improves Gut Microbiota as Evidenced by In Vivo and In Vitro Studies
- in-vivo, Arthritis, NA
*Inflam↓, *NLRP3↓, *GutMicro↑, *lipid-P↓, *ROS↓, *Cartilage↑, *IL6↓, *MMP13↓, *Dose↝,
3338- QC,    Quercetin: Its Antioxidant Mechanism, Antibacterial Properties and Potential Application in Prevention and Control of Toxipathy
- Review, Var, NA - Review, Stroke, NA
*antiOx↑, *GSH↑, *ROS↓, *Dose↑, *NADPH↓, *AMP↓, *NF-kB↓, *p38↑, *MAPK↑, *SOD↑, *MDA↓, *iNOS↓, *Catalase↑, *PI3K↑, *Akt↑, *lipid-P↓, *memory↑, *radioP↑, *neuroP↑, *MDA↓,
5969- Rad,  CET,    Radiotherapy plus cetuximab for locoregionally advanced head and neck cancer: 5-year survival data from a phase 3 randomised trial, and relation between cetuximab-induced rash and survival
- Trial, HNSCC, NA
Dose↝, radioP↑, OS↑,
5284- Ramu,    https://pmc.ncbi.nlm.nih.gov/articles/PMC4131847/
- Review, Var, NA
VEGFR2↓, OS↑, angioG↓, toxicity↝, ChemoSen↑, Dose↝,
6054- RES,  SeNPs,    Oral Administration of Resveratrol-Selenium-Peptide Nanocomposites Alleviates Alzheimer's Disease-like Pathogenesis by Inhibiting Aβ Aggregation and Regulating Gut Microbiota
- in-vivo, AD, NA
*Dose↝, *cognitive↑, *Aβ↓, *ROS↓, *TAC↑, *GutMicro↑, *BBB↑,
5781- RES,    Resveratrol improves health and survival of mice on a high-calorie diet
- in-vivo, Nor, NA
*AntiAge↑, *IGF-1↓, *AMPK↑, *CRM↑, *PGC-1α↑, *mtDam↓, *motorD↑, *hepatoP↑, *Dose↝,
5788- RES,    Calorie restriction-like effects of 30 days of Resveratrol (resVida™) supplementation on energy metabolism and metabolic profile in obese humans
- Trial, Nor, NA
*AMPK↑, *SIRT1↑, *PGC-1α↑, *BP↓, *CRM↑, *Dose↝, *mtDam↓, *ALAT↓, *hepatoP↑,
5797- RES,    Enhancing the Delivery of Resveratrol in Humans: If Low Bioavailability is the Problem, What is the Solution?
- Review, Nor, NA
*AntiAge↑, *Dose↑, *BioAv↑, *BioAv↑, *BioAv∅, *BioAv↑, *BioAv↑, *BioAv↑, *BioAv↑,
2334- RES,    Glut 1 in Cancer Cells and the Inhibitory Action of Resveratrol as A Potential Therapeutic Strategy
- Review, Var, NA
GLUT1↓, GlucoseCon↓, lactateProd↓, Akt↓, mTOR↓, Dose↝, SIRT6↑, PKM2↓, HK2↓, PFK1↓, ChemoSen↑,
2650- RES,    Oxidative Stress Inducers in Cancer Therapy: Preclinical and Clinical Evidence
- Review, Var, NA
ROS↑, Dose↝, NRF2↑, NAF1↓, ChemoSen↑, BioAv↓,
2565- RES,    https://onlinelibrary.wiley.com/doi/10.1111/j.1365-2141.2007.06788.x
- in-vitro, NA, NA - in-vivo, NA, NA
AntiAg↑, TXA2↑, PKCδ↑, Dose↝,
2441- RES,    Anti-Cancer Properties of Resveratrol: A Focus on Its Impact on Mitochondrial Functions
- Review, Var, NA
*toxicity↓, *BioAv↝, *Dose↝, *hepatoP↑, *neuroP↑, *AntiAg↑, *COX2↓, *antiOx↑, *ROS↓, *ROS↑, PI3K↓, Akt↓, NF-kB↓, Wnt↓, β-catenin/ZEB1↓, NRF2↑, GPx↑, HO-1↑, BioEnh?, PTEN↑, ChemoSen↑, eff↑, mt-ROS↑, Warburg↓, Glycolysis↓, GlucoseCon↓, GLUT1↓, lactateProd↓, HK2↓, EGFR↓, cMyc↓, ROS↝, MMPs↓, MMP7↓, survivin↓, TumCP↓, TumCMig↓, TumCI↓,
3079- RES,    Therapeutic role of resveratrol against hepatocellular carcinoma: A review on its molecular mechanisms of action
- Review, Var, NA
angioG↓, TumMeta↓, ChemoSen↑, NADPH↑, SIRT1↑, NF-kB↓, NLRP3↓, Dose↝, COX2↓, MMP9↓, PGE2↓, TIMP1↑, TIMP2↑, Sp1/3/4↓, p‑JNK↓, uPAR↓, ROS↓, CXCR4↓, IL6↓, Gli1↓, *ROS↓, *GSTs↑, *SOD↑, *Catalase↑, *GPx↑, *lipid-P↓, *GSH↑, eff↑, eff↑, eff↑,
3078- RES,    The Effects of Resveratrol on Prostate Cancer through Targeting the Tumor Microenvironment
- Review, Pca, NA
*ROS↓, ROS↑, DNAdam↑, Apoptosis↑, Hif1a↑, Casp3↑, Casp9↑, Cyt‑c↑, Dose↝, MMPs↓, MMP2↓, MMP9↓, EMT↓, E-cadherin↑, N-cadherin↓, AR↓,
3076- RES,    Resveratrol for targeting the tumor microenvironment and its interactions with cancer cells
- Review, Var, NA
IL6↓, MMPs↓, MMP2↓, MMP9↓, BioAv↓, Half-Life↑, BioAv↑, Dose↝, angioG↓, IL10↓, VEGF↓, NF-kB↓, COX2↓, SIRT1↑, Wnt↓, cMyc↓, STAT3↓, PTEN↑, ROS↑, RadioS↑, Hif1a↓, E-cadherin↓, Vim↓, angioG↓,
3055- RES,    Resveratrol and Tumor Microenvironment: Mechanistic Basis and Therapeutic Targets
- Review, Var, NA
BioAv↓, BioAv↓, Dose↑, eff↑, eff↑, Dose↑, BioAv↑, ROS↑, MMP↓, P21↑, p27↑, TumCCA↑, ChemoSen↑, COX2↓, 5LO↓, VEGF↓, IL1↓, IL6↓, IL8↓, AR↓, PSA↓, MAPK↓, Hif1a↓, Glycolysis↓, miR-21↓, PTEN↑, Half-Life↝, *IGF-1↓, *IGFBP3↑, Half-Life↓,
3056- RES,    Less is more for cancer chemoprevention: evidence of a non-linear dose response for the protective effects of resveratrol in humans and mice
- in-vivo, Nor, NA
*AMPK↑, *P21↑, *Dose↓, *chemoPv↑,
4357- RF,    Targeted treatment of cancer with radiofrequency electromagnetic fields amplitude-modulated at tumor-specific frequencies
- Review, Var, NA
other↝, Dose↝, AntiTum↑, Ca+2↝, eff↝,
3621- RosA,    Short-Term Study on the Effects of Rosemary on Cognitive Function in an Elderly Population
- Trial, AD, NA
*cognitive↑, *Dose↝, *BioAv↑,
1745- RosA,    Rosmarinic acid and its derivatives: Current insights on anticancer potential and other biomedical applications
- Review, Var, NA - Review, AD, NA
ChemoSideEff↓, ChemoSen↑, antiOx↑, MMP2↓, MMP9↓, p‑AMPK↑, DNMTs↓, tumCV↓, COX2↓, E-cadherin↑, Vim↓, N-cadherin↓, EMT↓, Casp3↑, Casp9↓, ROS↓, GSH↑, ERK↓, Akt↓, ROS↓, NF-kB↓, p‑IκB↓, p50↓, p65↓, neuroP↑, Dose↝,
1742- RosA,    Rosmarinic acid, a natural polyphenol, has a potential pro-oxidant risk via NADH-mediated oxidative DNA damage
- Analysis, Var, NA
ROS↑, eff↑, eff↑, eff↑, eff↑, eff↓, Dose↝, Dose↝,
3012- RosA,  Rad,    Rosmarinic Acid Prevents Radiation-Induced Pulmonary Fibrosis Through Attenuation of ROSMYPT1TGFβ1 Signaling Via miR-19b-3p
- in-vitro, Nor, IMR90
*Inflam↓, *ROS↓, *p‑NF-kB↓, *Rho↓, *ROCK1↓, *radioP↑, *MCP1↓, *RANTES↓, *ICAM-1↓, *PGC1A↑, *NOX4↓, *Dose↝,
3001- RosA,    Therapeutic Potential of Rosmarinic Acid: A Comprehensive Review
- Review, Var, NA
TumCP↓, Apoptosis↑, TumMeta↓, Inflam↓, *antiOx↑, *AntiAge↑, *ROS↓, BioAv↑, Dose↝, NRF2↑, P-gp↑, ATP↑, MMPs↓, cl‑PARP↓, Hif1a↓, GlucoseCon↓, lactateProd↓, Warburg↓, TNF-α↓, COX2↓, IL6↓, HDAC2↓, GSH↑, ROS↓, ChemoSen↑, *BG↓, *IL1β↓, *TNF-α↓, *IL6↓, *p‑JNK↓, *p38↓, *Catalase↑, *SOD↑, *GSTs↑, *VitC↑, *VitE↑, *GSH↑, *GutMicro↑, *cardioP↑, *ROS↓, *MMP↓, *lipid-P↓, *NRF2↑, *hepatoP↑, *neuroP↑, *P450↑, *HO-1↑, *AntiAge↑, *motorD↓,
4905- Sal,    Salinomycin as a drug for targeting human cancer stem cells
- Review, Var, NA
CSCs↓, selectivity↑, Apoptosis↑, Casp3↑, ROS↑, Wnt↓, cycD1/CCND1↓, Fibronectin↓, OXPHOS↓, Diff↑, Dose↝,
5038- SAS,  Rad,    Sulfasalazine, an inhibitor of the cystine-glutamate antiporter, reduces DNA damage repair and enhances radiosensitivity in murine B16F10 melanoma
- in-vivo, Melanoma, B16-F10
xCT↓, ROS↑, RadioS↓, GSH↓, selectivity↑, DNArepair↓, TumCCA↑, H2O2↑, Dose↝,
2549- SDT,    Landscape of Cellular Bioeffects Triggered by Ultrasound-Induced Sonoporation
- Review, Var, NA
sonoP↑, tumCV↓, MMP↓, ROS↑, Ca+2↑, eff↝, eff↑, selectivity↑, Half-Life↝, Dose↝, P-gp↓, ER Stress↑, other↑,
2536- SDT,    Sonodynamic Therapy: Rapid Progress and New Opportunities for Non-Invasive Tumor Cell Killing with Sound
- Review, Var, NA
ROS↑, eff↑, Dose?,
2551- SDT,    Sonoporation: Past, Present, and Future
- Review, Var, NA
other↝, sonoP↑, Dose↝,
2537- SDT,    Design and Challenges of Sonodynamic Therapy System for Cancer Theranostics: From Equipment to Sensitizers
- Review, Var, NA
Dose↝, eff↑, eff↑, eff↑, eff↑,

Showing Research Papers: 401 to 450 of 575
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* indicates research on normal cells as opposed to diseased cells
Total Research Paper Matches: 575

Pathway results for Effect on Cancer / Diseased Cells:


Redox & Oxidative Stress ⓘ

antiOx↓, 1,   antiOx↑, 2,   CYP1A1↑, 1,   CYP2E1↑, 1,   Ferroptosis↑, 1,   GPx↓, 1,   GPx↑, 1,   GSH↓, 7,   GSH↑, 2,   H2O2↑, 2,   HO-1↑, 1,   lipid-P↓, 1,   NAF1↓, 1,   NRF2↑, 3,   OXPHOS↓, 1,   ROS↓, 5,   ROS↑, 22,   ROS⇅, 1,   ROS↝, 1,   mt-ROS↑, 1,   xCT↓, 1,  

Mitochondria & Bioenergetics ⓘ

ATP↓, 1,   ATP↑, 1,   EGF↓, 1,   MMP↓, 7,   MMP↝, 1,   mtDam↑, 2,   OCR↓, 1,   XIAP↓, 1,  

Core Metabolism/Glycolysis ⓘ

p‑AMPK↑, 1,   cMyc↓, 2,   CYP3A4↓, 1,   GlucoseCon↓, 5,   GLUT2↓, 1,   Glycolysis↓, 4,   HK2↓, 4,   lactateProd↓, 5,   LDH↓, 1,   LDHA↓, 1,   NAD↑, 1,   NADPH↑, 1,   PFK↓, 1,   PFK1↓, 1,   PKM2↓, 2,   SIRT1↑, 2,   Warburg↓, 2,  

Cell Death ⓘ

Akt↓, 4,   Apoptosis↑, 7,   BAX↑, 2,   Bcl-2↓, 2,   Casp↓, 1,   Casp↑, 1,   Casp3↑, 6,   Casp8↑, 1,   Casp9↓, 1,   Casp9↑, 1,   Cyt‑c↑, 3,   Cyt‑c↝, 1,   DR4↑, 1,   Fas↓, 1,   Fas↑, 1,   Ferroptosis↑, 1,   hTERT/TERT↓, 1,   iNOS↓, 1,   p‑JNK↓, 1,   MAPK↓, 1,   MAPK↑, 2,   p27↑, 2,   survivin↓, 2,   Telomerase↓, 2,   TRAIL↑, 1,   TumCD↑, 2,  

Kinase & Signal Transduction ⓘ

HER2/EBBR2↓, 1,   Sp1/3/4↓, 1,  

Transcription & Epigenetics ⓘ

miR-21↓, 1,   other↑, 1,   other↝, 4,   tumCV↓, 4,  

Protein Folding & ER Stress ⓘ

CHOP↑, 1,   ER Stress↑, 2,  

Autophagy & Lysosomes ⓘ

LC3II↑, 1,   p62↓, 1,   TumAuto↑, 3,  

DNA Damage & Repair ⓘ

DNAdam↑, 5,   DNArepair↓, 1,   DNMTs↓, 1,   P53↑, 4,   P53↝, 1,   cl‑PARP↓, 1,   cl‑PARP↑, 1,   SIRT6↑, 1,  

Cell Cycle & Senescence ⓘ

CDK2↓, 1,   cycA1/CCNA1↓, 1,   CycB/CCNB1↓, 1,   cycD1/CCND1↓, 1,   P21↑, 4,   TumCCA↑, 7,  

Proliferation, Differentiation & Cell State ⓘ

CSCs↓, 1,   Diff↑, 1,   EMT↓, 3,   ERK↓, 3,   Gli1↓, 1,   GSK‐3β↓, 1,   HDAC↓, 1,   HDAC2↓, 1,   mTOR↓, 1,   PI3K↓, 1,   PTEN↑, 3,   STAT3↓, 1,   TumCG↓, 4,   Wnt↓, 3,  

Migration ⓘ

5LO↓, 1,   AntiAg↑, 1,   Ca+2↑, 2,   Ca+2↝, 1,   E-cadherin↓, 1,   E-cadherin↑, 2,   Fibronectin↓, 1,   ITGB1↓, 1,   ITGB6↓, 1,   Ki-67↓, 1,   MMP2↓, 3,   MMP7↓, 1,   MMP9↓, 4,   MMPs↓, 7,   N-cadherin↓, 2,   PKCδ↑, 1,   TIMP1↑, 1,   TIMP2↑, 1,   TumCI↓, 3,   TumCMig↓, 4,   TumCP↓, 8,   TumMeta↓, 3,   uPAR↓, 1,   Vim↓, 2,   β-catenin/ZEB1↓, 1,  

Angiogenesis & Vasculature ⓘ

angioG↓, 6,   EGFR↓, 2,   Hif1a↓, 6,   Hif1a↑, 1,   LOX1↓, 1,   NO↑, 2,   TXA2↑, 1,   VEGF↓, 4,   VEGFR2↓, 1,  

Barriers & Transport ⓘ

GLUT1↓, 4,   P-gp↓, 1,   P-gp↑, 1,   sonoP↑, 2,  

Immune & Inflammatory Signaling ⓘ

COX2↓, 6,   COX2↑, 1,   CXCR4↓, 1,   Igs↑, 1,   IL1↓, 1,   IL10↓, 2,   IL12↓, 1,   IL1β↓, 1,   IL1β↑, 1,   IL22↓, 1,   IL6↓, 6,   IL8↓, 1,   Inflam↓, 2,   p‑IκB↓, 1,   NF-kB↓, 7,   NF-kB↑, 1,   NK cell↑, 1,   p50↓, 1,   p65↓, 1,   PGE2↓, 1,   PSA↓, 1,   TLR4↓, 1,   TNF-α↓, 4,  

Protein Aggregation ⓘ

NLRP3↓, 1,  

Hormonal & Nuclear Receptors ⓘ

AR↓, 2,   ER(estro)↓, 1,  

Drug Metabolism & Resistance ⓘ

BioAv↓, 4,   BioAv↑, 5,   BioEnh?, 1,   ChemoSen↑, 13,   CYP1A2↑, 1,   CYP2A3/CYP2A6↓, 1,   Dose?, 3,   Dose↓, 2,   Dose↑, 3,   Dose⇅, 1,   Dose↝, 28,   Dose∅, 4,   eff↓, 4,   eff↑, 22,   eff↝, 3,   Half-Life↓, 1,   Half-Life↑, 1,   Half-Life↝, 2,   P450↓, 1,   RadioS↓, 1,   RadioS↑, 2,   selectivity↑, 12,  

Clinical Biomarkers ⓘ

AR↓, 2,   EGFR↓, 2,   HER2/EBBR2↓, 1,   hTERT/TERT↓, 1,   IL6↓, 6,   Ki-67↓, 1,   LDH↓, 1,   PSA↓, 1,  

Functional Outcomes ⓘ

AntiCan↑, 2,   AntiTum↑, 1,   chemoP↑, 1,   ChemoSideEff↓, 2,   memory↑, 1,   neuroP↑, 1,   OS↑, 5,   QoL↑, 1,   radioP↑, 1,   Risk↓, 1,   toxicity↓, 1,   toxicity↝, 1,   Weight↑, 1,  

Infection & Microbiome ⓘ

Diar⇅, 1,  
Total Targets: 219

Pathway results for Effect on Normal Cells:


Redox & Oxidative Stress ⓘ

antiOx↑, 5,   Catalase↑, 3,   GPx↑, 1,   GPx1↑, 1,   GSH↑, 3,   GSTs↑, 2,   HO-1↑, 1,   lipid-P↓, 4,   MDA↓, 2,   NOX4↓, 1,   NRF2↑, 1,   ROS↓, 10,   ROS↑, 2,   SOD↑, 3,   SOD1↑, 1,   SOD2↑, 1,   TAC↑, 1,   VitC↑, 1,   VitE↑, 1,  

Mitochondria & Bioenergetics ⓘ

MMP↓, 1,   mtDam↓, 2,   PGC-1α↑, 2,  

Core Metabolism/Glycolysis ⓘ

ALAT↓, 1,   AMP↓, 1,   AMPK↑, 3,   CRM↑, 2,   NADPH↓, 1,   PGC1A↑, 1,   SIRT1↑, 2,  

Cell Death ⓘ

Akt↑, 1,   iNOS↓, 1,   p‑JNK↓, 1,   MAPK↑, 1,   p38↓, 1,   p38↑, 1,  

Transcription & Epigenetics ⓘ

other↝, 1,  

DNA Damage & Repair ⓘ

DNAdam↑, 1,   DNAdam∅, 1,  

Cell Cycle & Senescence ⓘ

P21↑, 1,  

Proliferation, Differentiation & Cell State ⓘ

IGF-1↓, 2,   IGFBP3↑, 1,   PI3K↑, 1,  

Migration ⓘ

AntiAg↑, 1,   Cartilage↑, 1,   MMP13↓, 1,   Rho↓, 1,   ROCK1↓, 1,  

Barriers & Transport ⓘ

BBB↑, 1,  

Immune & Inflammatory Signaling ⓘ

COX2↓, 1,   ICAM-1↓, 1,   IL1β↓, 1,   IL6↓, 2,   Inflam↓, 4,   MCP1↓, 1,   NF-kB↓, 1,   p‑NF-kB↓, 1,   RANTES↓, 1,   TNF-α↓, 1,  

Protein Aggregation ⓘ

Aβ↓, 2,   NLRP3↓, 1,  

Drug Metabolism & Resistance ⓘ

BioAv↓, 2,   BioAv↑, 12,   BioAv↝, 1,   BioAv∅, 1,   Dose?, 1,   Dose↓, 1,   Dose↑, 2,   Dose↝, 11,   Dose∅, 1,   eff↑, 1,   Half-Life↝, 1,   P450↓, 1,   P450↑, 1,  

Clinical Biomarkers ⓘ

ALAT↓, 1,   BG↓, 1,   BP↓, 2,   GutMicro↑, 3,   IL6↓, 2,  

Functional Outcomes ⓘ

AntiAge↑, 4,   cardioP↑, 1,   chemoPv↑, 1,   cognitive↑, 4,   hepatoP↑, 4,   memory↑, 2,   motorD↓, 1,   motorD↑, 1,   neuroP↑, 4,   radioP↑, 2,   Risk↑, 1,   toxicity↓, 2,   toxicity↑, 1,   toxicity↝, 1,  
Total Targets: 92

Scientific Paper Hit Count for: Dose, Dosage
31 Selenium NanoParticles
30 Magnetic Fields
21 Curcumin
19 Resveratrol
18 Silver-NanoParticles
17 Vitamin C (Ascorbic Acid)
16 Selenium
16 Selenite (Sodium)
15 Radiotherapy/Radiation
14 Apigenin (mainly Parsley)
14 Propolis -bee glue
14 Hydrogen Gas
12 Chemotherapy
12 Carvacrol
12 Chlorogenic acid
11 EGCG (Epigallocatechin Gallate)
10 Sulforaphane (mainly Broccoli)
9 Baicalein
8 Auranofin
8 Lycopene
8 Magnetic Field Rotating
7 3-bromopyruvate
7 Capsaicin
7 chitosan
7 Citric Acid
7 Ellagic acid
7 Exercise
7 Silymarin (Milk Thistle) silibinin
7 Whole Body Vibration
6 5-Hydroxytryptophan
6 Astaxanthin
6 Melatonin
6 nicotinamide adenine dinucleotide
6 Copper and Cu NanoParticles
6 Dichloroacetate
6 Electrical Pulses
6 SonoDynamic Therapy UltraSound
6 Phenethyl isothiocyanate
5 Alpha-Lipoic-Acid
5 Allicin (mainly Garlic)
5 Acetyl-l-carnitine
5 Metformin
5 Aspirin -acetylsalicylic acid
5 Boron
5 Spermidine
5 Hydroxycinnamic-acid
5 diet FMD Fasting Mimicking Diet
5 Bicarbonate(Sodium)
5 Phenylbutyrate
5 Rosmarinic acid
5 Vitamin D3
5 VitK3,menadione
4 cetuximab
4 Ashwagandha(Withaferin A)
4 Berberine
4 Boswellia (frankincense)
4 Butyrate
4 Caffeic acid
4 Celastrol
4 immunotherapy
4 Chocolate
4 Coenzyme Q10
4 Oxygen, Hyperbaric
4 Shilajit/Fulvic Acid
4 Propyl gallate
4 Thymoquinone
3 Astragalus
3 Artemisinin
3 Aloe anthraquinones
3 beta-glucans
3 Bromelain
3 borneol
3 Cat’s Claw
3 Calorie Restriction Mimetics
3 HydroxyCitric Acid
3 Disulfiram
3 Fisetin
3 Honokiol
3 metronomic chemo
3 Methylsulfonylmethane
3 Piperlongumine
3 Shikonin
3 Aflavin-3,3′-digallate
3 Urolithin
3 Vitamin B1/Thiamine
3 Vitamin E
3 Vitamin K2
2 Glucose
2 almonertinib
2 Bevacizumab (brand Avastin)
2 Anti-oxidants
2 Ascorbyl Palmitate
2 Paclitaxel
2 Atorvastatin
2 Betulinic acid
2 beta-carotene(VitA)
2 Bicalutamide
2 Calcium
2 Sorafenib (brand name Nexavar)
2 Celecoxib
2 Chrysin
2 doxorubicin
2 Garcinol
2 diet Plant based
2 diet Short Term Fasting
2 Folic Acid, Vit B9
2 Gambogic Acid
2 Potassium
2 Luteolin
2 capecitabine
2 Iron
2 Niclosamide (Niclocide)
2 probiotics
2 Bifidobacterium
2 Silicic Acid
2 Vitamin B5,Pantothenic Acid
1 5-Aminolevulinic acid
1 Photodynamic Therapy
1 Cisplatin
1 Aromatherapy
1 Baicalin
1 Biochanin A
1 bempedoic acid
1 Bufalin/Huachansu
1 Brucea javanica
1 Bacopa monnieri
1 Bortezomib
1 brusatol
1 Bruteridin(bergamot juice)
1 urea
1 Catechins
1 Cannabidiol
1 Chlorophyllin
1 Choline
1 Camptothecin
1 Crocetin
1 CUSP9
1 diet Ketogenic
1 Docetaxel
1 Zinc
1 Emodin
1 Ferulic acid
1 Fenbendazole
1 Gallic acid
1 Ginkgo biloba
1 Ginger/6-Shogaol/Gingerol
1 Huperzine A/Huperzia serrata
1 itraconazole
1 Juglone
1 MCToil
1 nivolumab
1 magnetic nanoparticles
1 Mushroom Lion’s Mane
1 Naringin
1 Nimbolide
1 Oleuropein
1 Hyperthermia
1 Phosphatidylserine
1 Pterostilbene
1 Quercetin
1 Ramucirumab (CYRAMZA)
1 Radio Frequency
1 salinomycin
1 Sulfasalazine
1 irinotecan
1 Taurine
1 Thymol-Thymus vulgaris
1 Ursolic acid
1 Vitamin B6,pyridoxine
1 Vitamin B12
1 Transarterial Chemoembolization
1 Xylitol
Query results interpretion may depend on "conditions" listed in the research papers.
Such Conditions may include : 
  -low or high Dose
  -format for product, such as nano of lipid formations
  -different cell line effects
  -synergies with other products 
  -if effect was for normal or cancerous cells

Filter Conditions: Pro/AntiFlg:%  IllCat:%  CanType:%  Cells:%  prod#:%  Target#:1114  State#:%  Dir#:%
  wNotes=0  sortOrder:rid,rpid

 

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