BioAv Cancer Research Results

BioAv, bioavailability: Click to Expand ⟱
Source:
Type: measurement
Bioavailability (usually in %) absorbed by the body.
Scientific Papers found: Click to Expand⟱
6982- Form,    Formononetin: A Review of Its Anticancer Potentials and Mechanisms
- Review, Var, NA
AntiTum↑, Apoptosis↑, BAX↑, Bcl-2↓, Casp3↑, TumCCA↑, cycA1/CCNA1↓, CycB/CCNB1↓, cycD1/CCND1↓, TumCP↓, VEGF↓, FGF↓, MMP2↓, MMP9↓, eff↑, ChemoSen↑, chemoPv↑, p‑Akt↓, p‑STAT3↑, TumCMig↓, TumCI↓, TIMP1↑, TIMP2↑, PI3K↓, Akt↓, Dose↝, TumCG↓, TumW↓, TumVol↓, angioG↓, Casp3↑, Casp9↑, cl‑PARP↑, DNArepair↓, MMP↓, BAX↑, Bcl-2↓, DR5↑, ROS↑, eff↓, p‑ERK↓, PTEN↑, Hif1a↓, eff↑, eff↑, ChemoSen↑, HDAC↓, *BioAv↑, *Half-Life↝, *BioAv↝, *BioAv↑, *BioAv↑, *eff↑,
6992- Form,    Formononetin: pharmacological properties and therapeutic potential
- Review, Nor, NA
*BMD↑, *BioAv↑, *Half-Life↝, *BioAv↑,
6997- Form,  PI,    Formononetin–piperine–phospholipid complex: enhancement of anti-osteoporotic activity and bioavailability in bone marrow in rats
- in-vivo, ostP, NA
*BMD↑, *BioAv↑,
7012- Fuc,    Fucoidan: A promising natural therapeutic agent for protecting human kidney health
- Review, EC, NA
*RenoP↑, *Inflam↓, *antiOx↑, *ROS↓, *BloodF↑, *diuretic↑, *BioAv↓, *BioAv↑, *MAPK↓, *ERK↑, *NLRP3↓, *NRF2↑, *MDA↓, *SOD↑, *GPx↑, *Catalase↑, *lipid-P↓, *DNAdam↓, *Fibrosis↓, *JAK2↓, *STAT3↓, *uricA↓, *COL1↓, *α-SMA↓, *SIRT1↑, *HO-1↑, *GLP-1R↑, *HMGB1↓, *RAGE↓, *NF-kB↓, *TGF-β1↓, *PI3K↓, *Akt↓, *GutMicro↑, *SCFAs↑, *Buty↑, *IBI↑, *TJ↑, *Dose↝,
7013- Fuc,    Fucoidan-based nanoparticles for colorectal cancer therapy: Mechanisms and preclinical insights
- Review, CRC, NA
*Inflam↓, *antiOx↑, AntiCan↑, BioAv↑, Apoptosis↑, angioG↓, Imm↝, ChemoSen↑, chemoP↑,
7016- Fuc,    Therapies from Fucoidan: New Developments
- Review, Var, NA
*Bacteria↓, *BioAv↓, *Dose↝, *GutMicro↑, PD-1↝, ROS⇅, cl‑Casp↑, cl‑PARP↑, RadioS↑, *radioP↑, *neuroP↑, *Aβ↓,
7026- Fuc,    Fucoidan
- Review, AD, NA
*Inflam↓, *ROS↓, *BioAv↓, *GutMicro↑, *neuroP↑, *glucose↝, *AntiThr↑, *chemoP↑, *Half-Life↝, *BBB∅, *AntiAge↑, Risk↑,
7018- Fuc,    Absorption Study of Mozuku Fucoidan in Japanese Volunteers
- Trial, Nor, NA
*Dose↝, *BioAv↝, *eff↝, *Inflam↓, *AntiThr↑, angioG↓, *AntiViral↑, *AntiTum↑, *antiOx↓, *BioAv↝,
7025- Fuc,    Pilot clinical study to evaluate the anticoagulant activity of fucoidan
- Human, Nor, NA
*Dose↝, *BioAv↓, *antiCG↝,
6998- Fuc,    Detection of Fucoidan in Urine after Oral Intake of Traditional Japanese Seaweed, Okinawa mozuku (Cladosiphon okamuranus Tokida)
- Human, Nor, NA
*BioAv↝,
7006- Fuc,    Seaweeds in the Oncology Arena: Anti-Cancer Potential of Fucoidan as a Drug—A Review
- Review, Var, NA
*toxicity↓, *AntiViral↑, *antiOx↑, *Imm⇅, AntiCan↑, TumCCA↑, Apoptosis↑, TumMeta↓, angioG↓, antiNeop↑, VEGF↓, MMPs↓, BioAv↑, BioAv↑, ROS⇅, cl‑PARP↑, Casp3↑, Casp7↑, ROS↑, GSH↓, MMP↓, PI3K↓, ERK↓, MAPK↑, TumCP↓, Bax:Bcl2↑, TJ↑, ZO-1↑, OCLN↑, CLDN1↑, IBI↑, GutMicro↑, NK cell↑, STAT3↓, eff↑,
4027- FulvicA,    Mummy Induces Apoptosis Through Inhibiting of Epithelial-Mesenchymal Transition (EMT) in Human Breast Cancer Cells
- in-vitro, BC, MDA-MB-231 - in-vitro, BC, MCF7 - in-vitro, Nor, MCF10
tumCV↓, selectivity↑, TGF-β↓, Twist↓, NOTCH1↓, CTNNB1↓, Src↓, E-cadherin↑, EMT↓, TumMeta↓, BioAv↑,
4016- FulvicA,    Shilajit: A Natural Phytocomplex with Potential Procognitive Activity
- Review, AD, NA
*tau↓, *AntiAge↑, *Strength↑, *Dose↝, *BioAv↑, *antiOx↑, *memory↑, *Inflam↓, *cognitive↑, *neuroP↑, *toxicity↝, *toxicity↑,
947- GA,    Gallic acid, a phenolic compound, exerts anti-angiogenic effects via the PTEN/AKT/HIF-1α/VEGF signaling pathway in ovarian cancer cells
- in-vitro, Ovarian, OVCAR-3 - in-vitro, Melanoma, A2780S - in-vitro, Nor, IOSE364 - Human, NA, NA
TumCG↓, VEGF↓, angioG↓, p‑Akt↓, Hif1a↓, PTEN↑, BioAv↑, *toxicity↓,
7038- GA,    Gallic acid for cancer therapy: Molecular mechanisms and boosting efficacy by nanoscopical delivery
- Review, Var, NA
PI3K↓, Akt↓, ChemoSen↑, BioAv↑,
7044- GA,  QC,    Inhibitory effects of gallic acid and quercetin on UDP-glucose dehydrogenase activity
- in-vitro, BC, MCF7
UGDH↓, UGDH↓, TumCP↓, Dose↑, *BioAv↓, eff?,
7027- GA,    Pharmacokinetics of gallic acid and its relative bioavailability from tea in healthy humans
- Human, Nor, NA
AntiCan↑, *Inflam↓, *BioAv↑, *Half-Life↓, *eff↝,
1773- GA,    Impact of Gallic Acid on Gut Health: Focus on the Gut Microbiome, Immune Response, and Mechanisms of Action
- Review, Var, NA
antiOx↑, AntiCan↑, Inflam↓, GutMicro↑, BioAv↝, BioAv↓, BioAv↑, TumMeta↓,
7069- GABA,    United States Pharmacopeia (USP) Safety Review of Gamma-Aminobutyric Acid (GABA)
- Review, Nor, NA
*toxicity↓, *BP↓, *AntiDiabetic↑, *AntiCan↑, *antiOx↑, *Inflam↓, *AntiBio↑, *other↝, *cognitive↑, *GH↑, *Sleep↑, *BioAv↑, *Half-Life↝, *BBB↓, *eff↑,
7066- GamB,    Unravelling the Therapeutic Potential of Gambogic Acid: Deciphering Its Molecular Mechanism of Action and Emerging Role as an Anticancer Xanthone
- Review, Var, NA
angioG↓, TumMeta↓, ChemoSen↑, *cardioP↑, *Inflam↓, *AntiViral↑, *antiOx↑, NF-kB↓, TNF-α↓, COX2/PTGS2↓, iNOS↓, Apoptosis↑, TumAuto↑, TumCP↓, TumCI↓, BioAv↓, ROS↑, MMP↓, SIRT1↓, Akt↓, mTORC1↓, AMPK↑, LRIG1↑, ER Stress↑, Paraptosis↑, Ferroptosis↑, HSP90↓, GSH↓, lipid-P↑, GPx4↓, miR-21↓, PI3K↓, Akt↓, PTEN↑, ASAP2↓, CDK7↓,
7065- GamB,    Gambogic acid: A review of its pharmacological mechanisms against cancer
- Review, Var, NA
AntiTum↑, Apoptosis↑, TumCCA↑, angioG↓, Hif1a↓, VEGF↓, MMPs↓, TumMeta↓, NF-kB↓, PI3K↓, Akt↓, mTOR↓, MAPK↓, P-gp/ABCB1↓, Shh↓, Pyro↑, Casp3↑, GSDME↑, ChemoSen↑, RadioS↑, BioAv↓, Bcl-2↓, Mcl-1↓, BAX↑, Half-Life↓, ROS↑, miR-21↓, MMP2↓, MMP9↓,
5148- GamB,    Gambogic acid: A shining natural compound to nanomedicine for cancer therapeutics
- Review, Var, NA
AntiCan↑, angioG↓, ChemoSen↑, RadioS↑, VEGF↓, MMP2↓, MMP9↓, Telomerase↓, TrxR↓, ERK↓, HSP90↓, ROS↑, SIRT1↑, survivin↓, cFLIP↓, Casp3↑, Casp8↑, Casp9↑, BAD↓, BID↓, Bcl-2↓, BAX↑, STAT3↓, hTERT/TERT↓, NF-kB↓, Myc↓, Hif1a↓, FOXD3↑, BioAv↓, BioAv↑, P53↑, eff↓, OCR↓, MMP↓, PI3K↓, Akt↓, BBB↑, TumCG↓, TumMeta↓, BioAv↑,
7087- GAR,    Garcinol as an Epigenetic Modulator: Mechanisms of Anti-Cancer Activity and Therapeutic Potential
- Review, Var, NA
HATs↓, p300↓, CBP↓, NF-kB↓, STAT3↓, PI3K↓, Akt↓, MAPK↓, Wnt↓, β-catenin/ZEB1↓, Inflam↓, angioG↓, TumCP↓, TumMeta↓, TumCCA↑, EMT↓, CSCs↓, P53↑, TrxR↓, ROS↑, JNK↑, DNAdam↑, mt-Apoptosis↑, ER Stress↑, CHOP/DDIT3↑, DDIT4↑, TRIB3↑, SESN2↑, miR-218↑, eff↑, ChemoSen↑, BioAv↓, Half-Life↓, BioAv↑,
7086- GAR,    Garcinol: An emerging epigenetic modifier with versatile anticancer properties
- Review, Var, NA
AntiCan↑, TumCG↓, TumMeta↓, toxicity↓, Apoptosis↑, angioG↓, *BioAv↝, HATs↓, p300↓, CBP↓, PI3K↓, Akt↓, NF-kB↓, STAT↓, mTOR↓, DFF45↓, survivin↓, N-cadherin↓, Twist↓, MMP2↓, MMP3↓, MMP9↓, Mcl-1↓, EZH2↓, NOTCH↓, CXCR4↓, PGE2↓, VEGF↓, mPGES-1↓, CycB/CCNB1↓, CDK2↓, CDK4/6↓, iNOS↓, COX2/PTGS2↓, IL1↓, TNF-α↓, PARP↑, Bcl-2↓,
7084- GAR,    A unique in vivo pharmacokinetic profile, in vitro metabolic stability and hepatic first-pass metabolism of garcinol, a promising novel anticancer phytoconstituent, by liquid chromatography–mass spectrometry
- in-vivo, Nor, NA
*BioAv↝, *Dose↝, *Inflam↓, *antiOx↑, *chemoPv↑, Wnt↓, β-catenin/ZEB1↓, ERK↓, PI3K↓, Akt↓, NF-kB↓, STAT3↓, TumCP↓, antiNeop↑, ChemoSen↑, chemoP↑,
7094- GAR,    A multi-targeted approach of garcinol for obesity intervention: Mechanistic insights and possible clinical applications
- Review, Nor, NA
*Obesity↓, *Appetite↓, *GutMicro↑, BioAv↝,
7205- GBE,    Exploring the multifaceted role of ginkgolides and bilobalide from Ginkgo biloba in mitigating metabolic disorders
- Review, AD, NA
*antiOx↑, *Inflam↓, *neuroP↑, *ROS↓, *cardioP↑, *Obesity↓, *BioAv↓,
7127- Ge-132,    Synthesis and Evaluation of Novel Organogermanium Sesquioxides As Antitumor Agents
- vitro+vivo, Var, NA
eff↑, BioAv↑, RadioS↑,
7098- Geld,    Geldanamycins: Potent Hsp90 Inhibitors with Significant Potential in Cancer Therapy
- Review, Var, NA
HSP90↓, *toxicity↑, *toxicity↓, *BioAv↑, eff↑, *toxicity↓, other↝,
7109- GEN,    Single- and multiple-dose pharmacokinetics of genistein capsules in healthy chinese subjects: A phase I, randomized, open-label study
- Trial, Nor, NA
*Dose↝, *BioAv↝, *BioAv↝, *BioAv↝,
7103- GEN,    A Comprehensive Review of Genistein's Effects in Preclinical Models of Cervical Cancer
- Review, Cerv, NA
TumCP↓, Apoptosis↑, RadioS↑, ChemoSen↑, *antiOx↑, *Inflam↓, *Bacteria↓, *AntiViral↑, *AntiDiabetic↑, *neuroP↑, AntiCan↑, TumCG↓, TumCI↓, TumCCA↑, cl‑PARP↑, selectivity↑, CycB/CCNB1↓, CDK1↓, p‑cDC2↓, p‑ERK↓, p‑p38↑, p‑JNK↑, MMP9↓, TIMP1↑, BioAv↓, BioAv↑, Half-Life↑,
927- GEN,  PacT,    Bioenhancers from mother nature and their applicability in modern medicine
- Review, Nor, NA
*BioAv↑,
6572- Ger,    Pharmacokinetics of Geraniol and Its Metabolites in Mice After Oral Administration
- in-vivo, Nor, NA
BioAv↝, BBB↑, BioAv↝, Half-Life↝,
6571- Ger,    Unlocking the therapeutic potential of Geraniol: an alternative perspective for metabolic disease management
- Review, Obesity, NA
*lipidLev↓, *antiOx↓, Inflam↓, *ROS↓, *BioAv↑, *AntiDiabetic↑, *Obesity↓,
7276- GGB,    Pharmacokinetics of Ginkgolide B after Oral Administration of Three Different Ginkgolide B Formulations in Beagle Dogs
- in-vivo, Nor, NA
*Dose↝, *BioAv↑, *Dose↝,
7291- GGB,    Inhibition of P-glycoprotein leads to improved oral bioavailability of compound K, an anticancer metabolite of red ginseng extract produced by gut microflora
- in-vivo, Nor, NA
BioAv↑, eff↑,
7141- GI,    Synthesis of New Shogaol Analogues as NRF2 Activators and Evaluation of Their Anti-Inflammatory Activity, Modes of Action and Metabolic Stability
- Study, Nor, BV2
*eff↑, *eff↓, *NRF2↑, *Inflam↓, *eff↑, *antiOx↑, *neuroP↑, *COX2/PTGS2↓, *NF-kB↓, *eff↓, *BioAv↝, *BioAv↑,
7250- Gink,    Ginkgetin from Ginkgo biloba: mechanistic insights into anticancer efficacy
- Review, Var, NA
AntiCan↑, toxicity↓, ChemoSen↑, chemoP↑, TumCCA↑, TumCD↑, TumCI↓, angioG↓, Ferroptosis↑, Imm↑, MOMP↑, Cyt‑c↑, Casp↑, cl‑Casp3↑, cl‑Casp9↑, cl‑PARP↑, Apoptosis↑, ROS↑, TumAuto↑, GPx4↓, xCT/SLC7A11↓, RadioS↑, NRF2↓, HO-1↓, HSP90↓, Dose↝, Dose↝, BioAv↓, BioAv↝, CYP3A4↓, *toxicity↑, *toxicity↝,
7251- Gink,    Ginkgetin: A Promising Multitarget Agent for Diverse Diseases
- Review, Var, NA
*Inflam↓, *antiOx↓, AntiCan↑, *neuroP↑, *cardioP↑, *Bacteria↓, *ROS↓, *lipid-P↓, *NRF2↓, *Keap1↓, *NF-kB↓, *MAPK↓, MMP2↓, M2 MC↓, JAK2↓, STAT3↓, TumCP↓, Casp↑, ChemoSen↑, *BMD↑, *Aβ↓, *Stroke↓, *BioAv↓,
7280- Gins,    Pharmacokinetics of ginsenoside Rb1 and its metabolite compound K after oral administration of Korean Red Ginseng extract
- Trial, Nor, NA
*BioAv↑, *Half-Life↝, *eff↝,
7299- GlaB,    Functional and therapeutic effects of Glabrescione B delivery by liposomes on Hedgehog-dependent tumors
Gli1↓, BioAv↓, BioAv↑, HH↓, BioAv↓,
7300- GlaB,  ATO,    Targeting GLI1 and GLI2 with small molecule inhibitors to suppress GLI-dependent transcription and tumor growth
- in-vitro, Var, NA
Gli↓, HH↓, Gli1↓, BioAv↓,
7302- GlaB,    Glabrescione B delivery by self-assembling micelles efficiently inhibits tumor growth in preclinical models of Hedgehog-dependent medulloblastoma
- vitro+vivo, MB, NA
BioAv↑, Gli1↓, TumCG↓, Dose↝, BBB↑, HH↓,
4597- GoldNP,  Chit,    Influence of chitosan coating on the oral bioavailability of gold nanoparticles in rats
- in-vivo, NA, NA
*BioAv↑,
7321- Gos,    The potential roles of gossypol as anticancer agent: advances and future directions
- Review, Var, NA
other↝, BioAv↑, Bcl-2↓, Casp3↑, Casp9↑, MOMP↑, ROS↑, ATP↓, mtDam↑, Apoptosis↑, hTERT/TERT↓, Akt↓, TumAuto↑, LC3‑Ⅱ/LC3‑Ⅰ↑, NRF2↓, ARE↓, ICAM-1↓, CX43/GJA1↓, NF-kB↓, TLR4↓, IL6↓, Inflam↓, CUL5↝, CUL1↝, NOXA↑, TumCI↓, TumCMig↓, TumCA↓, FAK↓, MDM2↓, VEGF↓, angioG↓, HLA-I/II↑, Imm↑, Dose↝, Glycolysis↓, OXPHOS↓,
7311- Gos,    Systematic Review of Gossypol/AT-101 in Cancer Clinical Trials
- Review, CLL, NA
Dose↝, toxicity↓, PFS↓, OS↑, eff↑, BioAv↑, Bcl-2↓, ROS↑, MOMP↑, Dose↑, Casp3↑, Casp9↑, MMP↑, VEGF↓, APE1/APEX1↓, ChemoSen↑, RadioS↑, toxicity↑, AST↑, ALAT↑,
7314- Gos,    The BH3 mimetic (±) gossypol induces ROS-independent apoptosis and mitochondrial dysfunction in human A375 melanoma cells in vitro
- in-vitro, Melanoma, A375
Dose↝, ROS↑, selectivity↑, Half-Life↓, MMP↓, BioAv↑,
7337- Gra,    Synergistic interactions among flavonoids and acetogenins in Graviola (Annona muricata) leaves confer protection against prostate cancer
- in-vitro, Pca, NA
other↝, eff↝, BioAv↝, TumCD↓, TumCG↓, Dose↝, other↝,
7330- GSE,    Free radicals and grape seed proanthocyanidin extract: importance in human health and disease prevention
- Review, Var, NA
*BioAv↑, *ROS↓, AntiCan↑, selectivity↑, RenoP↑, *hepatoP↑, *DNAdam↓, *Stroke↓, *Bcl-2↑, cMyc↓,
7325- GSE,    The Effects of a Grape Seed Procyanidin Extract on Cytochrome P450 3A4 Activity and Inflammatory Mediators in the Lungs of Heavy Active and Former Smokers
- in-vitro, Lung, NA
*cardioP↑, *Inflam↓, BioAv↑, TNF-α↓, MIP‑1α/CCL3↓, GranB/GZMB↓,

Showing Research Papers: 401 to 450 of 746
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* indicates research on normal cells as opposed to diseased cells
Total Research Paper Matches: 746

Pathway results for Effect on Cancer / Diseased Cells:


NA, unassigned(tgid=0) ⓘ

APE1/APEX1↓, 1,   ASAP2↓, 1,   CDK7↓, 1,   CUL1↝, 1,   CUL5↝, 1,   CX43/GJA1↓, 1,   DDIT4↑, 1,   HLA-I/II↑, 1,   LRIG1↑, 1,   PFS↓, 1,   UGDH↓, 2,  

Redox & Oxidative Stress(tgid=1) ⓘ

antiOx↑, 1,   ARE↓, 1,   Ferroptosis↑, 2,   GPx4↓, 2,   GSH↓, 2,   HO-1↓, 1,   lipid-P↑, 1,   NRF2↓, 2,   OXPHOS↓, 1,   ROS↑, 10,   ROS⇅, 2,   TrxR↓, 2,   xCT/SLC7A11↓, 1,  

Mitochondria & Bioenergetics(tgid=3) ⓘ

ATP↓, 1,   MMP↓, 5,   MMP↑, 1,   mtDam↑, 1,   OCR↓, 1,  

Core Metabolism/Glycolysis(tgid=4) ⓘ

ALAT↑, 1,   AMPK↑, 1,   cMyc↓, 1,   CYP3A4↓, 1,   Glycolysis↓, 1,   SIRT1↓, 1,   SIRT1↑, 1,  

Cell Death(tgid=5) ⓘ

Akt↓, 10,   p‑Akt↓, 2,   Apoptosis↑, 9,   mt-Apoptosis↑, 1,   BAD↓, 1,   BAX↑, 4,   Bax:Bcl2↑, 1,   Bcl-2↓, 7,   BID↓, 1,   Casp↑, 2,   cl‑Casp↑, 1,   Casp3↑, 7,   cl‑Casp3↑, 1,   Casp7↑, 1,   Casp8↑, 1,   Casp9↑, 4,   cl‑Casp9↑, 1,   CBP↓, 2,   cFLIP↓, 1,   Cyt‑c↑, 1,   DR5↑, 1,   Ferroptosis↑, 2,   GranB/GZMB↓, 1,   GSDME↑, 1,   hTERT/TERT↓, 2,   iNOS↓, 2,   JNK↑, 1,   p‑JNK↑, 1,   MAPK↓, 2,   MAPK↑, 1,   Mcl-1↓, 2,   MDM2↓, 1,   MOMP↑, 3,   Myc↓, 1,   NOXA↑, 1,   p‑p38↑, 1,   Paraptosis↑, 1,   Pyro↑, 1,   survivin↓, 2,   Telomerase↓, 1,   TumCD↓, 1,   TumCD↑, 1,  

Kinase & Signal Transduction(tgid=6) ⓘ

FOXD3↑, 1,  

Transcription & Epigenetics(tgid=7) ⓘ

EZH2↓, 1,   HATs↓, 2,   miR-21↓, 2,   miR-218↑, 1,   other↝, 4,   tumCV↓, 1,  

Protein Folding & ER Stress(tgid=8) ⓘ

CHOP/DDIT3↑, 1,   ER Stress↑, 2,   HSP90↓, 4,  

Autophagy & Lysosomes(tgid=9) ⓘ

LC3‑Ⅱ/LC3‑Ⅰ↑, 1,   SESN2↑, 1,   TumAuto↑, 3,  

DNA Damage & Repair(tgid=10) ⓘ

DFF45↓, 1,   DNAdam↑, 1,   DNArepair↓, 1,   P53↑, 2,   PARP↑, 1,   cl‑PARP↑, 5,  

Cell Cycle & Senescence(tgid=11) ⓘ

CDK1↓, 1,   CDK2↓, 1,   cycA1/CCNA1↓, 1,   CycB/CCNB1↓, 3,   cycD1/CCND1↓, 1,   TumCCA↑, 6,  

Proliferation, Differentiation & Cell State(tgid=12) ⓘ

p‑cDC2↓, 1,   CSCs↓, 1,   CTNNB1↓, 1,   EMT↓, 2,   ERK↓, 3,   p‑ERK↓, 2,   FGF↓, 1,   Gli↓, 1,   Gli1↓, 3,   HDAC↓, 1,   HH↓, 3,   mTOR↓, 2,   mTORC1↓, 1,   NOTCH↓, 1,   NOTCH1↓, 1,   p300↓, 2,   PI3K↓, 9,   PTEN↑, 3,   Shh↓, 1,   Src↓, 1,   STAT↓, 1,   STAT3↓, 5,   p‑STAT3↑, 1,   TumCG↓, 7,   Wnt↓, 2,  

Migration(tgid=13) ⓘ

CDK4/6↓, 1,   CLDN1↑, 1,   E-cadherin↑, 1,   FAK↓, 1,   MMP2↓, 5,   MMP3↓, 1,   MMP9↓, 5,   MMPs↓, 2,   N-cadherin↓, 1,   TGF-β↓, 1,   TIMP1↑, 2,   TIMP2↑, 1,   TJ↑, 1,   TRIB3↑, 1,   TumCA↓, 1,   TumCI↓, 5,   TumCMig↓, 2,   TumCP↓, 8,   TumMeta↓, 8,   Twist↓, 2,   ZO-1↑, 1,   β-catenin/ZEB1↓, 2,  

Angiogenesis & Vasculature(tgid=14) ⓘ

angioG↓, 12,   Hif1a↓, 4,   VEGF↓, 8,  

Barriers & Transport(tgid=15) ⓘ

BBB↑, 3,   IBI↑, 1,   OCLN↑, 1,   P-gp/ABCB1↓, 1,  

Immune & Inflammatory Signaling(tgid=16) ⓘ

COX2/PTGS2↓, 2,   CXCR4↓, 1,   ICAM-1↓, 1,   IL1↓, 1,   IL6↓, 1,   Imm↑, 2,   Imm↝, 1,   Inflam↓, 4,   JAK2↓, 1,   M2 MC↓, 1,   MIP‑1α/CCL3↓, 1,   mPGES-1↓, 1,   NF-kB↓, 7,   NK cell↑, 1,   PD-1↝, 1,   PGE2↓, 1,   TLR4↓, 1,   TNF-α↓, 3,  

Drug Metabolism & Resistance(tgid=21) ⓘ

BioAv↓, 10,   BioAv↑, 19,   BioAv↝, 6,   ChemoSen↑, 13,   Dose↑, 2,   Dose↝, 8,   eff?, 1,   eff↓, 2,   eff↑, 9,   eff↝, 1,   Half-Life↓, 3,   Half-Life↑, 1,   Half-Life↝, 1,   RadioS↑, 7,   selectivity↑, 4,  

Clinical Biomarkers(tgid=22) ⓘ

ALAT↑, 1,   AST↑, 1,   EZH2↓, 1,   GutMicro↑, 2,   hTERT/TERT↓, 2,   IL6↓, 1,   Myc↓, 1,   TRIB3↑, 1,  

Functional Outcomes(tgid=23) ⓘ

AntiCan↑, 10,   antiNeop↑, 2,   AntiTum↑, 2,   chemoP↑, 3,   chemoPv↑, 1,   OS↑, 1,   RenoP↑, 1,   Risk↑, 1,   toxicity↓, 3,   toxicity↑, 1,   TumVol↓, 1,   TumW↓, 1,  
Total Targets: 210

Pathway results for Effect on Normal Cells:


NA, unassigned(tgid=0) ⓘ

AntiBio↑, 1,   antiCG↝, 1,   Buty↑, 1,   diuretic↑, 1,   GLP-1R↑, 1,   SCFAs↑, 1,   Stroke↓, 2,  

Redox & Oxidative Stress(tgid=1) ⓘ

antiOx↓, 3,   antiOx↑, 10,   Catalase↑, 1,   GPx↑, 1,   HO-1↑, 1,   Keap1↓, 1,   lipid-P↓, 2,   MDA↓, 1,   NRF2↓, 1,   NRF2↑, 2,   ROS↓, 6,   SOD↑, 1,   uricA↓, 1,  

Core Metabolism/Glycolysis(tgid=4) ⓘ

glucose↝, 1,   lipidLev↓, 1,   SIRT1↑, 1,  

Cell Death(tgid=5) ⓘ

Akt↓, 1,   Bcl-2↑, 1,   MAPK↓, 2,  

Transcription & Epigenetics(tgid=7) ⓘ

AntiThr↑, 2,   other↝, 1,  

DNA Damage & Repair(tgid=10) ⓘ

DNAdam↓, 2,  

Proliferation, Differentiation & Cell State(tgid=12) ⓘ

ERK↑, 1,   GH↑, 1,   PI3K↓, 1,   STAT3↓, 1,  

Migration(tgid=13) ⓘ

COL1↓, 1,   Fibrosis↓, 1,   RAGE↓, 1,   TGF-β1↓, 1,   TJ↑, 1,   α-SMA↓, 1,  

Barriers & Transport(tgid=15) ⓘ

BBB↓, 1,   BBB∅, 1,   IBI↑, 1,  

Immune & Inflammatory Signaling(tgid=16) ⓘ

COX2/PTGS2↓, 1,   HMGB1↓, 1,   Imm⇅, 1,   Inflam↓, 14,   JAK2↓, 1,   NF-kB↓, 3,  

Synaptic & Neurotransmission(tgid=18) ⓘ

tau↓, 1,  

Protein Aggregation(tgid=19) ⓘ

Aβ↓, 2,   NLRP3↓, 1,  

Drug Metabolism & Resistance(tgid=21) ⓘ

BioAv↓, 7,   BioAv↑, 18,   BioAv↝, 10,   Dose↝, 9,   eff↓, 2,   eff↑, 4,   eff↝, 3,   Half-Life↓, 1,   Half-Life↝, 5,  

Clinical Biomarkers(tgid=22) ⓘ

BloodF↑, 1,   BMD↑, 3,   BP↓, 1,   GutMicro↑, 4,   RAGE↓, 1,  

Functional Outcomes(tgid=23) ⓘ

AntiAge↑, 2,   AntiCan↑, 1,   AntiDiabetic↑, 3,   AntiTum↑, 1,   Appetite↓, 1,   cardioP↑, 4,   chemoP↑, 1,   chemoPv↑, 1,   cognitive↑, 2,   hepatoP↑, 1,   memory↑, 1,   neuroP↑, 7,   Obesity↓, 3,   radioP↑, 1,   RenoP↑, 1,   Sleep↑, 1,   Strength↑, 1,   toxicity↓, 5,   toxicity↑, 3,   toxicity↝, 2,  

Infection & Microbiome(tgid=24) ⓘ

AntiViral↑, 4,   Bacteria↓, 3,  
Total Targets: 87

Scientific Paper Hit Count for: BioAv, bioavailability
49 Curcumin
21 EGCG (Epigallocatechin Gallate)
20 chitosan
19 Quercetin
18 Baicalein
18 Chlorogenic acid
17 Resveratrol
16 Selenium NanoParticles
16 Sulforaphane (mainly Broccoli)
15 Apigenin (mainly Parsley)
15 Berberine
15 Chrysin
14 Pterostilbene
13 Thymoquinone
11 Silymarin (Milk Thistle) silibinin
11 Honokiol
11 Lycopene
10 Alpha-Lipoic-Acid
10 Carvacrol
10 Rosmarinic acid
9 Astaxanthin
9 borneol
8 Capsaicin
8 Crocetin
8 Emodin
8 Ferulic acid
8 Fucoidan
8 Piperlongumine
8 Urolithin
7 Allicin (mainly Garlic)
7 Artemisinin
7 Betulinic acid
7 Hydroxycinnamic-acid
7 Piperine
7 Fisetin
7 HydroxyTyrosol
7 Isoliquiritigenin
7 isoquercitrin
7 Luteolin
7 Phenethyl isothiocyanate
6 Silver-NanoParticles
6 Ashwagandha(Withaferin A)
6 Biochanin A
6 Thymol-Thymus vulgaris
6 Propolis -bee glue
6 Ellagic acid
6 Eugenol
5 beta-glucans
5 Baicalin
5 Boswellia (frankincense)
5 Centella asiatica / Gotu kola → asiaticoside
5 Cucurbitacin
5 Formononetin
5 Gallic acid
5 Inositol
5 Magnolol
5 Naringin
5 Selenite (Sodium)
4 1,8-Cineole
4 5-Hydroxytryptophan
4 Beta-Caryophyllene
4 Boron
4 Caffeic acid
4 Celastrol
4 Garcinol
4 Isovitexin
4 Phenylbutyrate
4 Vitamin C (Ascorbic Acid)
4 Shikonin
4 Aflavin-3,3′-digallate
3 Ascorbyl Palmitate
3 Gold NanoParticles
3 Berbamine
3 Folic Acid, Vit B9
3 Chocolate
3 Rutin
3 Cinnamon
3 Coenzyme Q10
3 Copper and Cu NanoParticles
3 Diclofenac
3 Disulfiram
3 Fenbendazole
3 Gambogic Acid
3 Genistein (soy isoflavone)
3 Glabrescione B
3 Gossypol/AT-101
3 Grapeseed extract
3 IP6 (Inositol 1,2,3,4,5,6-hexakisphosphate)
3 Lecithin
3 Magnetic Fields
3 Niclosamide (Niclocide)
3 Selenium
3 Silicic Acid
3 Spermidine
3 Terpinen-4-ol / Tea Tree Oil
2 3-bromopyruvate
2 Auranofin
2 Astragalus
2 Citric Acid
2 Chemotherapy
2 Aspirin
2 Paclitaxel/Taxol
2 Atorvastatin
2 immunotherapy
2 Radiotherapy/Radiation
2 Butyrate
2 Melatonin
2 Cynanbungeigenin C (CBC) and D (CBD)
2 Chlorophyllin
2 Choline
2 Camptothecin
2 Cynara scolymus/Globe Artichoke/Artichoke Extract
2 Dasatinib/Phyrago
2 Dichloroacetate
2 Deguelin
2 D-limonene
2 Evodiamine
2 flavonoids
2 Shilajit/Fulvic Acid
2 Geraniol
2 Ginkgolide B
2 Ginkgetin
2 Hydrogen Gas
2 HydroxyCitric Acid
2 isoflavones
2 isoorientin
2 Methyl salicylate / Sweet Birch oil
2 magnetic nanoparticles
2 nicotinamide adenine dinucleotide
2 Oleuropein
2 Turmerones
2 Ursolic acid
1 Aluminum
1 Anethole/trans-Anethole
1 Aromatherapy
1 Gemcitabine (Gemzar)
1 Aloe anthraquinones
1 doxorubicin
1 Docetaxel
1 xanthohumol
1 beta-carotene(VitA)
1 Bicalutamide
1 Bacopa monnieri
1 α-Bisabolol / Chamomile oil
1 Carnosic acid
1 urea
1 capecitabine
1 Catechins
1 Cat’s Claw
1 Cannabidiol
1 Zinc
1 irinotecan
1 Polyphenols
1 Cyclopamine
1 Dichloroacetophenone(2,2-)
1 Dandelion Root
1 Echinacea
1 Ginkgo biloba-EGb 761
1 Electrical Pulses
1 Eurycomanone
1 Sesame seeds and Oil
1 Mung Bean Sprouts
1 Kaempferol
1 MCToil
1 Gamma-aminobutyric acid
1 Ginkgo biloba
1 Germanium Organic/Ge-132 / propagermanium (organogermanium)
1 Geldanamycin
1 Ginger/6-Shogaol/Gingerol
1 Ginseng
1 Arsenic trioxide
1 Graviola
1 Germacranolide sesquiterpene lactone
1 Hibiscus sabdariffa
1 Hyperthermia
1 Huperzine A/Huperzia serrata
1 Hyperoside
1 Indole-3-carbinol
1 Isobavachalcone
1 iodine
1 Anthocyanins
1 itraconazole
1 Methylene blue
1 Metformin
1 Magnesium
1 Bicarbonate(Sodium)
1 Oleocanthal
1 Oxygen, Hyperbaric
1 Cisplatin
1 Psoralidin
1 Parthenolide
1 enzalutamide
1 Rauwolfia serpentina/Indian Snakeroot
1 salinomycin
1 Date Fruit Extract
1 cetuximab
1 Tomatine
1 Vitamin B3,Niacin
1 Vitamin D3
1 Vitamin E
1 Vitamin K2
1 Vitexin
Query results interpretion may depend on "conditions" listed in the research papers.
Such Conditions may include : 
  -low or high Dose
  -format for product, such as nano of lipid formations
  -different cell line effects
  -synergies with other products 
  -if effect was for normal or cancerous cells

Filter Conditions: Pro/AntiFlg:%  IllCat:%  CanType:%  Cells:%  prod#:%  Target#:792  State#:%  Dir#:%
  wNotes=0  sortOrder:rid,rpid

 

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