eff Cancer Research Results

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5926- CAR,    An Updated Review of Research into Carvacrol and Its Biological Activities
- Review, Nor, NA - Review, AD, NA - Review, asthmatic, NA
*Inflam↓, *antiOx↑, *neuroP↑, *BioAv↑, *toxicity↓, *Pain↓, *TRPV3↑, *NRF2↑, *Ca+2↑, *ATP↑, *5LO↓, *COX2↓, PGE2↓, *hepatoP↑, *AntiAg↑, *Diar↓, *cardioP↑, *other↝, *chemoPv↑, *cognitive↑, *AChE↓, *GastroP↑, *eff↑, *BChE↓, *CRP↓,
5862- carbop,  Cisplatin,    Molecular Mechanisms of Resistance and Toxicity Associated with Platinating Agents
- Review, Var, NA
DNAdam↑, ER Stress↑, UPR↑, ATF4↑, ATF6↑, XBP-1↑, GRP78/BiP↑, NP/CIPN↝, toxicity↝, eff↑, TrxR1⇅,
3869- Carno,    Carnosine, Small but Mighty—Prospect of Use as Functional Ingredient for Functional Food Formulation
- Review, AD, NA - Review, Stroke, NA
*ROS↓, *IronCh↑, *AntiAge↑, *antiOx↑, *Inflam↓, *neuroP↑, *lipid-P↓, *toxicity↓, *NOX4↓, *SOD↑, *HNE↓, *IL6↓, *TNF-α↓, *IL1β↓, *Sepsis↓, *eff↑, *GABA↝, *Aβ↓, Glycolysis↓, AntiTum↑, p‑Akt↓, TumCCA↑, angioG↓, VEGFR2↓, NF-kB↓,
5916- Cats,  Chemo,    Uncaria tomentosa—Adjuvant Treatment for Breast Cancer: Clinical Trial
- Trial, BC, NA
*DNAdam↓, Neut↓, eff↑, Imm↑, Dose↝,
5917- Cats,    Uncaria tomentosa for Reducing Side Effects Caused by Chemotherapy in CRC Patients: Clinical Trial
- Trial, CRC, NA
Dose↝, *DNArepair↑, toxicity↝, BioAv↝, eff∅,
5920- Cats,    Treatment with Uncaria tomentosa Promotes Apoptosis in B16-BL6 Mouse Melanoma Cells and Inhibits the Growth of B16-BL6 Tumours
- in-vivo, Melanoma, B16-BL6
eff↑, Ki-67↓, TumCP↓, Apoptosis↑, TumCG↓,
5914- Cats,    Induction of apoptosis by Uncaria tomentosa through reactive oxygen species production, cytochrome c release, and caspases activation in human leukemia cells
- in-vitro, AML, HL-60
*Inflam↓, eff↑, DNAdam↑, Cyt‑c↑, Casp3↑, PARP↑, Fas↑, proCasp8↑, cl‑BID↑, BAX↑, Bcl-xL↑, cl‑Mcl-1↑,
5811- CBC,    The Potential of Cannabichromene (CBC) as a Therapeutic Agent
- Review, Var, NA
*eff?, *Half-Life↝, *Inflam↓,
5814- CBD,    Cannabis and Cannabinoids in Adults With Cancer: ASCO Guideline
- Review, Var, NA
eff↓,
5816- CBD,    Cannabidiol inhibits human glioma by induction of lethal mitophagy through activating TRPV4
- in-vitro, GBM, NA
TRPV2↑, Ca+2↑, MitoP↑, eff↑,
5817- CBD,    COX-2 and PPAR-γ confer cannabidiol-induced apoptosis of human lung cancer cells
- vitro+vivo, Lung, A549
AntiTum⇅, tumCV↓, Apoptosis↑, eff↓, COX2↑, PPARγ↑,
5818- CBD,    Cannabidiol's cytotoxicity in pancreatic cancer is induced via an upregulation of ceramide synthase 1 and ER stress
- in-vivo, PC, PANC1
GRP78/BiP↑, ATF4↑, CHOP↑, UPR↑, TumCG↓, ER Stress↑, eff↓,
5979- CDT,  AgNPs,    Multifunctional nanomedicines-enabled chemodynamic-synergized multimodal tumor therapy via Fenton and Fenton-like reactions
- Review, Var, NA
Fenton↑, eff↑,
5973- CDT,    Chemodynamic Therapy via Fenton and Fenton-Like Nanomaterials: Strategies and Recent Advances
- Review, Var, NA
Fenton↑, selectivity↑, eff↑,
5966- CEL,    Determine whether administering celecoxib during radiotherapy can reduce the risk of recurrence of triple-negative breast cancer. Pilot study
- Trial, BC, NA
Risk↓, eff↑,
5960- CEL,    Phase II, Randomized, Placebo-Controlled Trial of Neoadjuvant Celecoxib in Men With Clinically Localized Prostate Cancer: Evaluation of Drug-Specific Biomarkers
- Trial, Pca, NA
eff∅, Dose↝, CardioT↑,
5953- Cela,  CUR,    The Combination of Celastrol and Curcumin Enhances the Antitumor Effect in Nasopharyngeal Carcinoma by Inducing Ferroptosis
- vitro+vivo, NPC, NA
eff↑, TumCP↓, GPx4↓, eff↑, TumAuto↑, Ferroptosis↑, Dose↝, ACSL4↑, toxicity↓,
5941- Cela,    Celastrol inhibits migration and invasion through blocking the NF-κB pathway in ovarian cancer cells
- in-vitro, Ovarian, SKOV3 - in-vitro, Ovarian, OVCAR-3
TumCMig↓, TumCI↓, NF-kB↓, p65↓, MMP9↓, eff↑, AntiTum↑, Inflam↓, AntiDiabetic↑,
5942- Cela,    Celastrol elicits antitumor effects by inhibiting the STAT3 pathway through ROS accumulation in non-small cell lung cancer
- vitro+vivo, NSCLC, H460 - in-vitro, NSCLC, PC9
TumCG↓, TumCP↓, TumMeta↓, ROS↑, ER Stress↑, p‑STAT3↓, Apoptosis↑, eff↓, TumCG↓, IL6↓, other↝,
5943- Cela,    Celastrol: A Spectrum of Treatment Opportunities in Chronic Diseases
- Review, Arthritis, NA - Review, IBD, NA - Review, AD, NA - Review, Park, NA
*other↝, *other↝, *CRP↓, *eff↝, *other↑, *CXCR4↓, *IL1β↓, *IL6↓, *IL17↓, *IL18↓, *TNF-α↓, *MMP9↓, *PGE2↓, *COX1↓, *COX2↓, *PI3K↓, *Akt↓, *other↑, TumCCA↑, Apoptosis↑, ROS↑, JNK↑, TumAuto↑, Hif1a↓, BNIP3↝, HSP90↓, Fas↑, FasL↑, ETC↓, VEGF↓, angioG↓, RadioS↑, *neuroP↑, *HSP70/HSPA5↑, *ROS↓, *MMP↑, *Cyt‑c↓, *Casp3↓, *Casp9↓, *MAPK↓, *Dose⇅, *HSPs↑, BioAv↓, Dose↝,
5948- Cela,    Recent Trends in anti-tumor mechanisms and molecular targets of celastrol
TumCP↓, TumCCA↑, Apoptosis↑, TumAuto↑, TumCI↓, TumMeta↓, Imm↝, angioG↓, Cyt‑c↑, ROS↑, BAX↑, Casp3↑, Casp9↑, cl‑PARP↑, PrxII↓, ER Stress↑, mtDam↑, CHOP↑, Inflam↓, NF-kB↓, CXCR4↓, MMP9↓, IL6↓, TNF-α↓, HSP90↓, neuroP↑, STAT3↓, Prx↓, HO-1↑, eff↑, eff↑, BioAv↑, toxicity↑, CardioT↑, hepatoP↓,
5949- Cela,    Celastrol suppresses invasion of colon and pancreatic cancer cells through the downregulation of expression of CXCR4 chemokine receptor
- in-vitro, BC, MCF7
CXCR4↓, eff↑, TumCI↓, TumMeta↓,
6635- Cen,    Pharmacokinetics and metabolomics investigation of an orally modified formula of standardized Centella asiatica extract in healthy volunteers
- Trial, Nor, NA
*BioAv↝, *eff↑, *Choline↑, *memory↑, *cognitive↑, *neuroP↑, *BioAv↑,
6656- Cen,    Recent insights into therapeutic potential and nanostructured carrier systems of Centella asiatica: An evidence-based review
- Review, Var, NA - Review, AD, NA
AntiCan↑, *AntiDiabetic↑, *neuroP↑, *antiOx↑, *cardioP↑, *Inflam↓, *hepatoP↑, *AntiAge↑, *AST↓, *ALAT↓, *LDH↓, *lipid-P↓, Casp3↑, *memory↑, *Wound Healing↑, eff↑,
6645- Cen,    Can Asiatic Acid from Centella asiatica Be a Potential Remedy in Cancer Therapy?—A Review
- Review, Var, NA
TumCD↑, TumCG↓, TumMeta↓, PI3K↓, Akt↓, mTOR↓, P70S6K↓, STAT3↓, N-cadherin↓, β-catenin/ZEB1↓, CLDN1↓, Vim↓, TumAuto↑, *BioAv↓, Casp3↑, ROS↑, MMP15↓, MMP↓, eff↑, *toxicity↓,
6649- Cen,    Centella asiatica Extract Improves Behavioral Deficits in a Mouse Model of Alzheimer's Disease: Investigation of a Possible Mechanism of Action
- in-vivo, AD, NA
*eff↑, *memory↑, *NO↓, *cognitive↑, *AChE∅,
6646- Cen,    Effectiveness of Gotu Kola Extract 750 mg and 1000 mg Compared with Folic Acid 3 mg in Improving Vascular Cognitive Impairment after Stroke
- Trial, Stroke, NA
*eff↑, *memory↑, *cognitive↑, *AST∅, *ALAT∅, *AChE↓, *toxicity↓,
5968- CET,    Cetuximab as a Key Partner in Personalized Targeted Therapy for Metastatic Colorectal Cancer
- in-vitro, CRC, NA
eff↑, Half-Life↑, Half-Life↑, EGFR↓, OS↑, QoL↑, eff↑, KRAS↓,
5967- CET,    FDA grants accelerated approval to adagrasib with cetuximab for KRAS G12C-mutated colorectal cancer
- Study, CRC, NA
eff↑, Dose↝,
6020- CGA,  BetaL,    Chlorogenic Acid Enhances Beta‐Lapachone‐Induced Cell Death by Suppressing Autophagy in NQO1‐Positive Cancer Cells
- in-vitro, BC, MDA-MB-231
eff↑, Apoptosis↑, PKA↑, eff↑,
6019- CGA,  immuno,    Combination immunotherapy of chlorogenic acid liposomes modified with sialic acid and PD-1 blockers effectively enhances the anti-tumor immune response and therapeutic effects
- in-vivo, Melanoma, NA
eff↑, Dose↝, AntiTum↑, eff↑,
6018- CGA,    Chlorogenic acid: a review on its mechanisms of anti-inflammation, disease treatment, and related delivery systems
- Review, Var, NA - Review, RCC, NA
*BioAv↓, *Inflam↓, *TNF-α↓, *NO↓, *COX2↓, *PGE2↓, *NF-kB↓, *IL6↓, *IL1β↓, *TLR2↓, *MAPK↓, *NRF2↓, *HO-1↑, *NQO1↑, *cardioP↑, *neuroP↑, *SOD↑, *GSH↑, *ROS↓, *LDH↓, *MDA↓, *cognitive↑, *eff↑,
6017- CGA,    Therapeutic Potential of Chlorogenic Acid in Chemoresistance and Chemoprotection in Cancer Treatment
- Review, Var, NA
AntiCan↑, *chemoP↑, TNF-α↓, COX2↓, IL6↓, eff↑, PD-L1↓, *cognitive↓, *Aβ↓, *TAC↑, *SOD↑, *eff↑, *eff↑, ChemoSen↑, tumCV↓, Apoptosis↑, ERK↓, chemoP↑, *GPx↑, *GSTs↑, *GSH↑, *SOD↑, *Catalase↑, *ROS↓, *lipid-P↓, *MDA↓, *Casp3↓, *HO-1↓, cardioP↑, radioP↑,
6016- CGA,    Coffee Chlorogenic Acids Incorporation for Bioactivity Enhancement of Foods: A Review
- Review, Var, NA - Review, AD, NA - Review, Diabetic, NA
antiOx↑, *Bacteria↓, AntiCan↑, *Inflam↓, *cardioP↑, *AntiDiabetic↑, *GutMicro↑, *eff↑, *eff↑, *ROS↓, *IronCh↑, *neuroP↑, *AChE↓, *BChE↓, *chemoPv↑, *BioAv⇅,
6002- CGA,    Chlorogenic Acid: A Systematic Review on the Biological Functions, Mechanistic Actions, and Therapeutic Potentials
- Review, Var, NA - Review, Diabetic, NA - Review, AD, NA - Review, Park, NA - Review, Stroke, NA
*neuroP↑, *Inflam↓, *antiOx↑, *cardioP↑, *NRF2↑, *AMPK↑, *SOD↑, *Catalase↑, *GSH↑, *GPx↑, *ROS↓, *TNF-α↓, *IL6↓, *NF-kB↓, *COX2↓, *glucose↓, *TRPC1↓, *Ca+2↓, *HO-1↑, *NF-kB↓, *PPARα↝, *Hif1a↓, *JNK↓, *BP↓, *AntiDiabetic↑, *hepatoP↑, *TLR4↓, *NRF2↑, *Casp↓, *neuroP↑, *Aβ↓, *LDH↓, *MDA↓, *memory↑, *AChE↓, *eff↑, EMT↝, N-cadherin↓, E-cadherin↑, TumCCA↑, ROS↑, p‑P53↑, HO-1↑, NRF2↑, ChemoSen↑, mtDam↑, Casp3↑, Casp9↑, PARP↑, Bax:Bcl2↑, TumCG↓, cycD1/CCND1↓, cMyc↓, CDK2↓, mitResp↓, Glycolysis↓, Hif1a↓, PCNA↓, p‑GSK‐3β↓, VEGF↓, PI3K↓, Akt↓, mTOR↓, OS↑,
6013- CGA,    Advances in Pharmacological Properties, Molecular Mechanisms, and Bioavailability Strategies of Chlorogenic Acid in Cardiovascular Diseases Therapy
- Review, CardioV, NA
*BioAv↝, *BioAv↝, *BP↓, *ROS↓, *NADPH↓, *AntiAg↑, *TXA2↓, *antiOx↑, *cardioP↑, *Inflam↓, *SOD↑, *Catalase↑, *Ferroptosis↓, *NF-kB↓, *JNK↓, *NRF2↑, *HO-1↑, *toxicity↓, *BioAv↓, *BioAv↑, *BioAv↑, eff↑,
6008- CGA,    Risk Assessment of Chlorogenic and Isochlorogenic Acids in Coffee By-Products
- Review, Nor, NA
*toxicity↓, *antiOx↑, *Bacteria↓, *AntiDiabetic↑, *neuroP↑, *Inflam↓, *cardioP↑, *BP↓, *other↓, eff↓,
6038- CGA,    Neuromodulation and neuroprotective effects of chlorogenic acids in excitatory synapses of mouse hippocampal slices
- in-vivo, AD, NA - in-vivo, Stroke, NA
*eff↑, *other↓, *Risk↓, *cognitive↑, *neuroP↑, *antiOx↑,
6037- CGA,    Pharmacokinetics and brain penetration study of chlorogenic acid in rats
- in-vivo, AD, NA - in-vivo, Stroke, NA
*Dose↝, *eff↑, *BioAv↑, *eff↑,
6036- CGA,    Effect of Chlorogenic Acids on Cognitive Function: A Randomized, Double-Blind, Placebo-Controlled Trial
- Trial, Nor, NA
*motorD↑, *cognitive↑, *eff↑,
6034- CGA,    Effect and mechanism of chlorogenic acid on cognitive dysfunction in mice by lipopolysaccharide-induced neuroinflammation
- in-vivo, AD, NA
*cognitive↑, *TNF-α↓, *antiOx↑, *Inflam↓, *neuroP↑, *BBB↑, *eff↑, *memory↑, *AKT1↓, *MMP9↓, *MAPK↓,
6033- CGA,  CA,    Comparative study on the inhibitory effect of caffeic and chlorogenic acids on key enzymes linked to Alzheimer's disease and some pro-oxidant induced oxidative stress in rats' brain-in vitro
- in-vivo, AD, NA
*AChE↓, *BChE↓, *eff↑, *eff↑, *neuroP↑,
6630- CGA,    In Vitro and In Silico Study on the Impact of Chlorogenic Acid in Colorectal Cancer Cells: Proliferation, Apoptosis, and Interaction with β-Catenin and LRP6
- in-vitro, CRC, HT29 - in-vitro, CRC, SW480
tumCV↓, DNAdam↑, mt-ROS↑, MMP↓, Casp3↑, eff↝,
1244- CGA,  immuno,    Cancer Differentiation Inducer Chlorogenic Acid Suppresses PD-L1 Expression and Boosts Antitumor Immunity of PD-1 Antibody
- in-vivo, NA, NA
PD-L1↓, T-Cell↑, eff↑,
2175- Chemo,  VitB12,  FA,    Systemic Chemotherapy Interferes in Homocysteine Metabolism in Breast Cancer Patients
- Study, BC, NA
other↓, other↝, homoC↓, eff↝, other↝,
6025- Chit,    Glycated chitosan as a new non-toxic immunological stimulant
- vitro+vivo, Var, HeLa
*Imm↑, *BioAv↑, eff↑, *toxicity↓, *TNF-α↑, *Obesity↓,
6000- Chit,    Chitosan in Modern Pharmacotherapy: From Drug Encapsulation to Targeted Delivery Systems
- Review, Var, NA
DDS↑, toxicity↓, TJ↓, BioAv↑, *Bacteria↓, *Inflam↓, *antiOx↓, Wound Healing↑, other↝, eff↑, eff↑,
6001- Chit,    Recent advances in engineering chitosan-based nanoplatforms in biotherapeutic multi-delivery for multi-targeted disease treatments: Promises and outlooks
- Review, Var, HepG2 - Review, AD, NA
TumVol↓, toxicity↓, Half-Life↑, eff↑, selectivity↑, Dose↝, *BDNF↑, *NRF2↑, *ROS↓, *neuroP↑, *memory↑, *cognitive↑, *Obesity↓,
5981- Chit,    Chitosan-Based Drug Delivery Systems for Targeted Chemotherapy in Colorectal Cancer: A Scoping Review
- Review, CRC, NA
DDS↑, eff↑, BioAv↑, BioEnh↑, eff↑,
5984- Chit,    Chitosan in cancer therapy: a dual role as a therapeutic agent and drug delivery system
- Review, Var, NA
DDS↑, BioAv↑, TumCP↓, angioG↓, TumMeta↓, Apoptosis↑, eff↑,

Showing Research Papers: 401 to 450 of 1426
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* indicates research on normal cells as opposed to diseased cells
Total Research Paper Matches: 1426

Pathway results for Effect on Cancer / Diseased Cells:


Redox & Oxidative Stress(tgid=1) ⓘ

antiOx↑, 1,   Fenton↑, 2,   Ferroptosis↑, 1,   GPx4↓, 1,   HO-1↑, 2,   NRF2↑, 1,   Prx↓, 1,   PrxII↓, 1,   ROS↑, 5,   mt-ROS↑, 1,   TrxR1⇅, 1,  

Mitochondria & Bioenergetics(tgid=3) ⓘ

ETC↓, 1,   mitResp↓, 1,   MMP↓, 2,   mtDam↑, 2,  

Core Metabolism/Glycolysis(tgid=4) ⓘ

ACSL4↑, 1,   cMyc↓, 1,   Glycolysis↓, 2,   homoC↓, 1,   PPARγ↑, 1,  

Cell Death(tgid=5) ⓘ

Akt↓, 2,   p‑Akt↓, 1,   Apoptosis↑, 8,   BAX↑, 2,   Bax:Bcl2↑, 1,   Bcl-xL↑, 1,   cl‑BID↑, 1,   Casp3↑, 6,   proCasp8↑, 1,   Casp9↑, 2,   Cyt‑c↑, 2,   Fas↑, 2,   FasL↑, 1,   Ferroptosis↑, 1,   JNK↑, 1,   cl‑Mcl-1↑, 1,   TumCD↑, 1,  

Kinase & Signal Transduction(tgid=6) ⓘ

TRPV2↑, 1,  

Transcription & Epigenetics(tgid=7) ⓘ

other↓, 1,   other↝, 4,   tumCV↓, 3,  

Protein Folding & ER Stress(tgid=8) ⓘ

ATF6↑, 1,   CHOP↑, 2,   ER Stress↑, 4,   GRP78/BiP↑, 2,   HSP90↓, 2,   UPR↑, 2,   XBP-1↑, 1,  

Autophagy & Lysosomes(tgid=9) ⓘ

BNIP3↝, 1,   MitoP↑, 1,   TumAuto↑, 4,  

DNA Damage & Repair(tgid=10) ⓘ

DNAdam↑, 3,   p‑P53↑, 1,   PARP↑, 2,   cl‑PARP↑, 1,   PCNA↓, 1,  

Cell Cycle & Senescence(tgid=11) ⓘ

CDK2↓, 1,   cycD1/CCND1↓, 1,   TumCCA↑, 4,  

Proliferation, Differentiation & Cell State(tgid=12) ⓘ

EMT↝, 1,   ERK↓, 1,   p‑GSK‐3β↓, 1,   mTOR↓, 2,   P70S6K↓, 1,   PI3K↓, 2,   STAT3↓, 2,   p‑STAT3↓, 1,   TumCG↓, 6,  

Migration(tgid=13) ⓘ

Ca+2↑, 1,   CLDN1↓, 1,   E-cadherin↑, 1,   Ki-67↓, 1,   KRAS↓, 1,   MMP15↓, 1,   MMP9↓, 2,   N-cadherin↓, 2,   PKA↑, 1,   TJ↓, 1,   TumCI↓, 3,   TumCMig↓, 1,   TumCP↓, 5,   TumMeta↓, 5,   Vim↓, 1,   β-catenin/ZEB1↓, 1,  

Angiogenesis & Vasculature(tgid=14) ⓘ

angioG↓, 4,   ATF4↑, 2,   EGFR↓, 1,   Hif1a↓, 2,   VEGF↓, 2,   VEGFR2↓, 1,  

Immune & Inflammatory Signaling(tgid=16) ⓘ

COX2↓, 1,   COX2↑, 1,   CXCR4↓, 2,   IL6↓, 3,   Imm↑, 1,   Imm↝, 1,   Inflam↓, 2,   Neut↓, 1,   NF-kB↓, 3,   p65↓, 1,   PD-L1↓, 2,   PGE2↓, 1,   T-Cell↑, 1,   TNF-α↓, 2,  

Drug Metabolism & Resistance(tgid=21) ⓘ

BioAv↓, 1,   BioAv↑, 4,   BioAv↝, 1,   BioEnh↑, 1,   ChemoSen↑, 2,   DDS↑, 3,   Dose↝, 8,   eff↓, 5,   eff↑, 33,   eff↝, 2,   eff∅, 2,   Half-Life↑, 3,   RadioS↑, 1,   selectivity↑, 2,  

Clinical Biomarkers(tgid=22) ⓘ

EGFR↓, 1,   IL6↓, 3,   Ki-67↓, 1,   KRAS↓, 1,   PD-L1↓, 2,  

Functional Outcomes(tgid=23) ⓘ

AntiCan↑, 3,   AntiDiabetic↑, 1,   AntiTum↑, 3,   AntiTum⇅, 1,   cardioP↑, 1,   CardioT↑, 2,   chemoP↑, 1,   hepatoP↓, 1,   neuroP↑, 1,   NP/CIPN↝, 1,   OS↑, 2,   QoL↑, 1,   radioP↑, 1,   Risk↓, 1,   toxicity↓, 3,   toxicity↑, 1,   toxicity↝, 2,   TumVol↓, 1,   Wound Healing↑, 1,  
Total Targets: 142

Pathway results for Effect on Normal Cells:


Redox & Oxidative Stress(tgid=1) ⓘ

antiOx↓, 1,   antiOx↑, 8,   Catalase↑, 3,   Ferroptosis↓, 1,   GPx↑, 2,   GSH↑, 3,   GSTs↑, 1,   HNE↓, 1,   HO-1↓, 1,   HO-1↑, 3,   lipid-P↓, 3,   MDA↓, 3,   NOX4↓, 1,   NQO1↑, 1,   NRF2↓, 1,   NRF2↑, 5,   ROS↓, 8,   SOD↑, 6,   TAC↑, 1,  

Metal & Cofactor Biology(tgid=2) ⓘ

IronCh↑, 2,  

Mitochondria & Bioenergetics(tgid=3) ⓘ

ATP↑, 1,   MMP↑, 1,  

Core Metabolism/Glycolysis(tgid=4) ⓘ

AKT1↓, 1,   ALAT↓, 1,   ALAT∅, 1,   AMPK↑, 1,   glucose↓, 1,   LDH↓, 3,   NADPH↓, 1,   PPARα↝, 1,  

Cell Death(tgid=5) ⓘ

Akt↓, 1,   Casp↓, 1,   Casp3↓, 2,   Casp9↓, 1,   Cyt‑c↓, 1,   Ferroptosis↓, 1,   JNK↓, 2,   MAPK↓, 3,  

Kinase & Signal Transduction(tgid=6) ⓘ

TRPV3↑, 1,  

Transcription & Epigenetics(tgid=7) ⓘ

other↓, 2,   other↑, 2,   other↝, 3,  

Protein Folding & ER Stress(tgid=8) ⓘ

HSP70/HSPA5↑, 1,   HSPs↑, 1,  

DNA Damage & Repair(tgid=10) ⓘ

DNAdam↓, 1,   DNArepair↑, 1,  

Proliferation, Differentiation & Cell State(tgid=12) ⓘ

Choline↑, 1,   PI3K↓, 1,  

Migration(tgid=13) ⓘ

5LO↓, 1,   AntiAg↑, 2,   Ca+2↓, 1,   Ca+2↑, 1,   MMP9↓, 2,   TRPC1↓, 1,  

Angiogenesis & Vasculature(tgid=14) ⓘ

Hif1a↓, 1,   NO↓, 2,   TXA2↓, 1,  

Barriers & Transport(tgid=15) ⓘ

BBB↑, 1,   GastroP↑, 1,  

Immune & Inflammatory Signaling(tgid=16) ⓘ

COX1↓, 1,   COX2↓, 4,   CRP↓, 2,   CXCR4↓, 1,   IL17↓, 1,   IL18↓, 1,   IL1β↓, 3,   IL6↓, 4,   Imm↑, 1,   Inflam↓, 12,   NF-kB↓, 4,   PGE2↓, 2,   TLR2↓, 1,   TLR4↓, 1,   TNF-α↓, 5,   TNF-α↑, 1,  

Synaptic & Neurotransmission(tgid=18) ⓘ

AChE↓, 5,   AChE∅, 1,   BChE↓, 3,   BDNF↑, 1,   GABA↝, 1,  

Protein Aggregation(tgid=19) ⓘ

Aβ↓, 3,  

Drug Metabolism & Resistance(tgid=21) ⓘ

BioAv↓, 3,   BioAv↑, 6,   BioAv⇅, 1,   BioAv↝, 3,   Dose⇅, 1,   Dose↝, 1,   eff?, 1,   eff↑, 18,   eff↝, 1,   Half-Life↝, 1,  

Clinical Biomarkers(tgid=22) ⓘ

ALAT↓, 1,   ALAT∅, 1,   AST↓, 1,   AST∅, 1,   BP↓, 3,   CRP↓, 2,   GutMicro↑, 1,   IL6↓, 4,   LDH↓, 3,  

Functional Outcomes(tgid=23) ⓘ

AntiAge↑, 2,   AntiDiabetic↑, 4,   cardioP↑, 7,   chemoP↑, 1,   chemoPv↑, 2,   cognitive↓, 1,   cognitive↑, 9,   hepatoP↑, 3,   memory↑, 7,   motorD↑, 1,   neuroP↑, 14,   Obesity↓, 2,   Pain↓, 1,   Risk↓, 1,   toxicity↓, 7,   Wound Healing↑, 1,  

Infection & Microbiome(tgid=24) ⓘ

Bacteria↓, 3,   Diar↓, 1,   Sepsis↓, 1,  
Total Targets: 119

Scientific Paper Hit Count for: eff, efficacy
69 Silver-NanoParticles
58 Magnetic Fields
49 Curcumin
43 Sulforaphane (mainly Broccoli)
35 Vitamin C (Ascorbic Acid)
32 Thymoquinone
32 Chemotherapy
29 immunotherapy
28 Shikonin
26 chitosan
26 EGCG (Epigallocatechin Gallate)
25 Piperlongumine
24 Artemisinin
24 Quercetin
23 Resveratrol
23 Selenium NanoParticles
23 Selenite (Sodium)
22 Copper and Cu NanoParticles
22 Baicalein
21 Dichloroacetate
20 Radiotherapy/Radiation
20 Ashwagandha(Withaferin A)
20 Berberine
18 Chlorogenic acid
18 Capsaicin
18 Chrysin
18 Magnetic Field Rotating
17 Apigenin (mainly Parsley)
17 Phenylbutyrate
16 Metformin
16 diet FMD Fasting Mimicking Diet
16 Gambogic Acid
16 Bicarbonate(Sodium)
15 Selenium
15 Lycopene
14 Citric Acid
14 Propolis -bee glue
14 Exercise
14 Phenethyl isothiocyanate
13 3-bromopyruvate
13 Caffeic acid
12 Cisplatin
12 Betulinic acid
12 Disulfiram
12 Fisetin
11 Folic Acid, Vit B9
11 Auranofin
11 Melatonin
11 borneol
11 doxorubicin
11 salinomycin
11 Dandelion Root
11 Rosmarinic acid
10 Alpha-Lipoic-Acid
10 Luteolin
10 Atorvastatin
10 Boron
10 Choline
10 Vitamin K2
10 Silymarin (Milk Thistle) silibinin
10 diet Methionine-Restricted Diet
10 Honokiol
10 VitK3,menadione
10 Urolithin
9 Coenzyme Q10
9 Gold NanoParticles
9 SonoDynamic Therapy UltraSound
9 Vitamin D3
9 Ellagic acid
9 Carvacrol
9 Electrical Pulses
9 Eugenol
9 Hydrogen Gas
8 Photodynamic Therapy
8 Hyperthermia
8 Chlorophyllin
8 Docosahexaenoic Acid
8 Plumbagin
8 Parthenolide
7 5-fluorouracil
7 Docetaxel
7 Carnosic acid
7 Piperine
6 Vitamin B12
6 Fenbendazole
6 Allicin (mainly Garlic)
6 Dipyridamole
6 beta-glucans
6 Bifidobacterium
6 Celastrol
6 Diclofenac
6 HydroxyCitric Acid
6 Spermidine
6 Juglone
6 Terpinen-4-ol / Tea Tree Oil
5 1,8-Cineole
5 Astragalus
5 chemodynamic therapy
5 Akkermansia
5 Bevacizumab (brand Avastin)
5 Gemcitabine (Gemzar)
5 Aspirin
5 Ascorbyl Palmitate
5 Astaxanthin
5 Berbamine
5 beta-carotene(VitA)
5 Bortezomib
5 Boswellia (frankincense)
5 Thymol-Thymus vulgaris
5 Centella asiatica / Gotu kola → asiaticoside
5 diet Plant based
5 Echinacea
5 MCToil
5 Magnolol
5 Moringa oleifera
5 Nimbolide
4 2-DeoxyGlucose
4 cetuximab
4 almonertinib
4 Andrographis
4 α-Bisabolol / Chamomile oil
4 Butyrate
4 capecitabine
4 Cat’s Claw
4 Cannabidiol
4 CUSP9
4 erastin
4 diet Short Term Fasting
4 Propyl gallate
4 Pterostilbene
4 Sulfasalazine
4 Whole Body Vibration
3 Anthocyanins
3 Zinc
3 Anti-oxidants
3 Aloe anthraquinones
3 D-limonene
3 Biochanin A
3 Beta-Caryophyllene
3 bempedoic acid
3 Lutein
3 Zeaxanthin
3 Bufalin/Huachansu
3 temozolomide
3 hydroxychloroquine
3 Chocolate
3 Cichoric acid / Chicoric acid
3 Calorie Restriction Mimetics
3 Cysteamine
3 Ginseng
3 Lecithin
3 nicotinamide adenine dinucleotide
3 Naringin
3 Radio Frequency
3 Taurine
3 Vitamin B1/Thiamine
2 5-Aminolevulinic acid
2 Glucose
2 Anethole/trans-Anethole
2 Vitamin A, Retinoic Acid
2 Aromatherapy
2 Sorafenib (brand name Nexavar)
2 Trastuzumab
2 Arsenic trioxide
2 Baicalin
2 brusatol
2 Caffeic Acid Phenethyl Ester (CAPE)
2 Rutin
2 Caffeine
2 Calcium
2 carboplatin
2 Celecoxib
2 Cinnamon
2 Hydroxycinnamic-acid
2 Crocetin
2 Cucurbitacin
2 Cyclopamine
2 Dichloroacetophenone(2,2-)
2 Dasatinib/Phyrago
2 Deguelin
2 Date Fruit Extract
2 Oxygen, Hyperbaric
2 Emodin
2 ferumoxytol
2 Kaempferol
2 Genistein (soy isoflavone)
2 γ-linolenic acid (Borage Oil)
2 Orlistat
2 Potassium
2 Methylene blue
2 metronomic chemo
2 Methylsulfonylmethane
2 Mushroom Lion’s Mane
2 Niclosamide (Niclocide)
2 Phosphatidylserine
2 Aflavin-3,3′-digallate
2 tetrathiomolybdate
1 Serotonin, 5-hydroxytryptamine
1 dietMediterranean
1 Trichostatin A
1 wortmannin
1 Resiquimod
1 EMF
1 Anzaroot, Astragalus fasciculifolius Bioss
1 Ajoene (compound of Garlic)
1 Acetyl-l-carnitine
1 Amodiaquine
1 DTS(dibenzyl trisulphide) from Anamu
1 Fennel Oil/Foeniculum vulgare
1 Huperzine A/Huperzia serrata
1 probiotics
1 Brucea javanica
1 Bacopa monnieri
1 Bromelain
1 Bruteridin(bergamot juice)
1 urea
1 Carnosine
1 Cannabichromene
1 Beta‐Lapachone
1 Carica papaya leaf extract
1 Camptothecin
1 irinotecan
1 Carvone
1 Black phosphorus
1 gefitinib, erlotinib
1 eicosapentaenoic acid
1 Dihydrocaffeic Acid
1 diet Fermented Foods
1 diet Ketogenic
1 Mistletoe
1 Lemongrass Extract/Citral
1 PXD, phenoxodiol
1 Eurycomanone
1 Ferulic acid
1 Vitamin E
1 flavonoids
1 Flickering Light Stimulation
1 verapamil
1 Garcinol
1 Geraniol
1 tamoxifen
1 HydroxyTyrosol
1 itraconazole
1 Laetrile B17 Amygdalin
1 lambertianic acid
1 Linalool
1 Matrine
1 Methyl Jasmonate
1 methotrexate
1 Magnesium
1 Methylglyoxal
1 Mushroom Reishi
1 Myricetin
1 No Product/Mechanism Only
1 Oleocanthal
1 Peppermint
1 sericin
1 Paclitaxel
1 Psoralidin
1 enzalutamide
1 Oxaliplatin
1 α-Santalol/Sandalwood oil
1 Scoulerine
1 polyethylene glycol
1 acetaminophen
1 Formononetin
1 acetazolamide
1 Iron
1 Squalene
1 Glutathione
1 statins
1 Sutherlandioside D
1 triptolide
1 Tumor Treating Fields
1 Turmerones
1 Ursolic acid
1 Vitamin B3,Niacin
1 Vitamin B5,Pantothenic Acid
1 Vitamin B6,pyridoxine
1 Wogonin
Query results interpretion may depend on "conditions" listed in the research papers.
Such Conditions may include : 
  -low or high Dose
  -format for product, such as nano of lipid formations
  -different cell line effects
  -synergies with other products 
  -if effect was for normal or cancerous cells

Filter Conditions: Pro/AntiFlg:%  IllCat:%  CanType:%  Cells:%  prod#:%  Target#:961  State#:%  Dir#:%
  wNotes=0  sortOrder:rid,rpid

 

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