Cancer Database Query Results

Scientific Papers found: Click to Expand⟱
1992- PTL,    Parthenolide induces ROS-dependent cell death in human gastric cancer cell
- in-vitro, BC, MGC803
TumCCA↑, Casp↑, Apoptosis↑, Necroptosis↑, RIP1↓, RIP3↑, MLKL↑, ROS↑, eff↓,
1993- PTL,    Parthenolide induces apoptosis and autophagy through the suppression of PI3K/Akt signaling pathway in cervical cancer
- in-vitro, Cerv, HeLa
tumCV↓, TumAuto↑, Casp3↑, BAX↑, Beclin-1↑, ATG3↑, ATG5↑, Bcl-2↓, mTOR↓, PI3K↓, Akt↓, PTEN↑, ROS↑, MMP↓,
1994- PTL,    Parthenolide Inhibits Tumor Cell Growth and Metastasis in Melanoma A2058 Cells
- in-vitro, Melanoma, A2058 - in-vitro, Nor, L929
tumCV↓, selectivity?, ROS?, BAX↑, TumCCA?, MMP2↓, MMP9↓, TumCMig↓, eff↑,
1983- PTL,    Targeting thioredoxin reductase by micheliolide contributes to radiosensitizing and inducing apoptosis of HeLa cells
- in-vitro, Cerv, HeLa
eff↑, TrxR↓, ROS↑, RadioS↑,
1236- PTS,    Pterostilbene inhibits the metastasis of TNBC via suppression of β-catenin-mediated epithelial to mesenchymal transition and stemness
- in-vitro, BC, MCF-7 - in-vitro, BC, MDA-MB-231 - in-vitro, BC, MDA-MB-468
TumMeta↓, EMT↓, E-cadherin↑, Zeb1↓, Snail↓, β-catenin/ZEB1↓, CD44↓, MMPs↓, CSCs↓,
1237- PTS,    Pterostilbene induces cell apoptosis and inhibits lipogenesis in SKOV3 ovarian cancer cells by activation of AMPK-induced inhibition of Akt/mTOR signaling cascade
- in-vitro, Ovarian, SKOV3
TumCMig↓, TumCI↓, MDA↑, ROS↑, BAX↑, Casp3↑, Bcl-2↓, SREBP1↓, FASN↓, AMPK↓, p‑AMPK↑, p‑P53↑, p‑TSC2↑, p‑Akt↓, p‑mTOR↓, p‑S6K↓, p‑4E-BP1↓,
1238- PTS,    Pterostilbene suppresses gastric cancer proliferation and metastasis by inhibiting oncogenic JAK2/STAT3 signaling: In vitro and in vivo therapeutic intervention
- in-vitro, GC, NA - in-vivo, NA, NA
TumCCA↑, TumCP↓, TumCMig↓, TumCI↓, TumVol↓, TumW↓, Weight∅, JAK2↓, STAT3↓,
3925- PTS,    Analysis of Safety from a Human Clinical Trial with Pterostilbene
- Trial, NA, NA
*toxicity↓, *Half-Life↑, *BioAv↑,
3930- PTS,    A Review of Pterostilbene Antioxidant Activity and Disease Modification
- Review, Var, NA - Review, adrenal, NA - Review, Stroke, NA
*BioAv↑, *antiOx↑, *neuroP↑, *Inflam↓, *ROS↓, *H2O2↓, *GSH↑, *GPx↑, *GSR↑, *SOD↑, TumCG↓, PTEN↑, HGF/c-Met↓, PI3K↓, Akt↓, NF-kB↓, TumMeta↓, MMP2↓, MMP9↓, Ki-67↓, Casp3↑, MMP↓, H2O2↑, ROS↑, ChemoSen↑, *cardioP↑, *CDK2↓, *CDK4↓, *cycE/CCNE↓, *cycD1/CCND1↓, *RB1↓, *PCNA↓, *CREB↑, *GABA↑, *memory↑, *IGF-1↑, *ERK↑, TIMP1↑, BAX↑, Cyt‑c↑, Diablo↑, SOD2↑,
3929- PTS,    New Insights into Dietary Pterostilbene: Sources, Metabolism, and Health Promotion Effects
- Review, Var, NA - Review, Arthritis, NA
*NRF2↑, *BioAv↑, *ROS↓, *Inflam↓, *HO-1↑, *SOD↑, *Catalase↑, *GPx↑, *lipid-P↓, *hepatoP↑, *neuroP↑, *iNOS↓, *COX2↓, TumMeta↓, SOD2↓, ROS↑, TumCI↓, TumCG↓, HDAC1↓, PTEN↑, BP↓, *GutMicro↑,
3931- PTS,    Pterostilbene Protects against Osteoarthritis through NLRP3 Inflammasome Inactivation and Improves Gut Microbiota as Evidenced by In Vivo and In Vitro Studies
- in-vivo, Arthritis, NA
*Inflam↓, *NLRP3↓, *GutMicro↑, *lipid-P↓, *ROS↓, *Cartilage↑, *IL6↓, *MMP13↓, *Dose↝,
3928- PTS,    The effects of pterostilbene on neutrophil activity in experimental model of arthritis
- in-vivo, Arthritis, NA
*ROS↓, *Neut↓,
3927- PTS,    Effects of Pterostilbene on Cardiovascular Health and Disease
- Review, AD, NA - Review, Stroke, NA
*Inflam↓, *antiOx↑, *BioAv↑, *toxicity↓, *NADPH↓, *ROS↓, *Catalase↑, *GSH↑, *SOD↑, *TNF-α↓, *IL1β↓, *IL4↓, *MMPs↓, *COX2↓, *MAPK↝, *NF-kB↓, *IL8↓, *MCP1↓, *E-sel↓, *lipid-P↓, *NRF2↑, *PPARα↑, *LDL↓, other↓,
3926- PTS,    Pterostilbene exert an anti-arthritic effect by attenuating inflammation, oxidative stress, and alteration of gut microbiota
- in-vivo, Arthritis, NA
*Inflam↓, *GutMicro↑, *ROS↓,
3924- PTS,    Effect of resveratrol and pterostilbene on aging and longevity
- Review, AD, NA - Review, Stroke, NA
*antiOx↓, *ROS↑, *SOD↑, *GSH↑, *NRF2↑, *MDA↓, *HNE↓, *Inflam↓, *MAPK↓, *IL6↓, *TNF-α↓, *HO-1↑, *cardioP↑, *neuroP↑, *CRM↑, *NLRP3↓,
3923- PTS,    Pterostilbene Supplement Benefits: Longevity Miracle or Hoax
- Review, AD, NA
*BioAv↑, *Half-Life↑, *BBB↑, *BP↓, *cognitive↑,
3922- PTS,    Pterostilbene attenuates amyloid-β induced neurotoxicity with regulating PDE4A-CREB-BDNF pathway
- in-vivo, AD, NA
*BioAv↑, *BBB↑, *memory↑, *p‑CREB↑, *BDNF↑, *PSD95↑, *neuroP↑,
3920- PTS,    Resveratrol, pterostilbene, and dementia
- Review, AD, NA
*cognitive↑,
3919- PTS,    Low-dose pterostilbene, but not resveratrol, is a potent neuromodulator in aging and Alzheimer's disease
- in-vivo, AD, NA
*cognitive↑, *SIRT1∅, *PPARα↑, *SOD2↑, *JNK↓, *p‑tau↓,
3918- PTS,    Pterostilbene inhibits amyloid-β-induced neuroinflammation in a microglia cell line by inactivating the NLRP3/caspase-1 inflammasome pathway
- in-vitro, AD, BV2
*IL6↓, *IL1β↓, *TNF-α↓, *NLRP3↓, *Inflam↓, *NO↓, *iNOS↓,
5033- PTS,    Involvement of the Nrf2 Pathway in the Regulation of Pterostilbene-Induced Apoptosis in HeLa Cells via ER Stress
- in-vitro, Cerv, HeLa
ER Stress↑, ROS↑, NRF2↑, TumCP↓, GSH/GSSG↓,
5032- PTS,    Pterostilbene Decreases the Antioxidant Defenses of Aggressive Cancer Cells In Vivo: A Physiological Glucocorticoids- and Nrf2-Dependent Mechanism
- in-vivo, Melanoma, NA
TumCG↓, NRF2↓, GR↓, BBB↑, ACTH↓, eff↑,
5034- PTS,    Pterostilbene in Cancer Therapy
- Review, Var, NA
BioAv↓, Half-Life↓, iNOS↓, Apoptosis↑, STAT3↓, Akt↓, mTOR↓, NF-kB↓, NRF2↓, ChemoSen↑, BBB↑,
4693- PTS,    Pterostilbene in the treatment of inflammatory and oncological diseases
BioAv↑, *Inflam↓, *antiOx↑, AntiTum↑, BBB↑, Half-Life↝, *ROS↓, *NRF2↑, *NQO1↑, *HO-1↑, PTEN↑, miR-19b↓, TumCCA↑, ER Stress↑, PERK↑, ATF4↑, CHOP↑, Ca+2↝, EMT↓, NF-kB↓, Twist↓, Vim↓, E-cadherin↑, ChemoSen↑, toxicity∅, toxicity↝,
4704- PTS,  Cisplatin,    Pterostilbene Sensitizes Cisplatin-Resistant Human Bladder Cancer Cells with Oncogenic HRAS
- in-vitro, Bladder, NA
PI3K↓, mTOR↓, P70S6K↓, MEK↑, ERK↑, ChemoSen↑, TumAuto↑,
4703- PTS,  RES,    Pterostilbene and resveratrol: Exploring their protective mechanisms against skin photoaging - A scoping review
- NA, Nor, NA
*AntiAge↑, *eff↑, *Inflam↓, *AntiCan↑, *ROS↓, *Catalase↑, *GSR↑, *HO-1↑, *NAD↑, *NQO1↑, *SOD↑, *NRF2↑,
4702- PTS,    Pterostilbene Inhibits Pancreatic Cancer In Vitro
- in-vitro, PC, MIA PaCa-2 - in-vitro, PC, PANC1
tumCV↓, TumCG↓, BioAv↑,
4701- PTS,  RES,    Targeting cancer stem cells and signaling pathways by resveratrol and pterostilbene
- Review, Var, NA
CSCs↓, E-cadherin↑, NF-kB↓, EMT↓, GRP78/BiP↓, CD133↓, COX2↓, β-catenin/ZEB1↓, NOTCH↓,
4700- PTS,    Pterostilbene, a bioactive component of blueberries, suppresses the generation of breast cancer stem cells within tumor microenvironment and metastasis via modulating NF-κB/microRNA 448 circuit
- in-vitro, BC, MDA-MB-231 - in-vitro, BC, MCF-7
CSCs↓, NF-kB↓, Twist↓, Vim↓, E-cadherin↑,
4699- PTS,    Pterostilbene inhibits triple-negative breast cancer metastasis via inducing microRNA-205 expression and negatively modulates epithelial-to-mesenchymal transition
- in-vitro, BC, MDA-MB-231 - in-vitro, BC, HS587T - in-vivo, BC, MDA-MB-231
TumCMig↓, TumCI↓, E-cadherin↑, Snail↓, Slug↓, Vim↓, Zeb1↑, miR-205↑, Src↓, TumCG↓, FAK↓, EMT↓,
4698- PTS,    Pterostilbene, a bioactive component of blueberries, suppresses the generation of breast cancer stem cells within tumor microenvironment and metastasis via modulating NF ‐κ B /microRNA 448 circuit
- in-vitro, BC, MCF-7 - in-vitro, BC, MDA-MB-231
CSCs↓, NF-kB↓, Twist↓, Vim↓, E-cadherin↑, miR-448↑,
4697- PTS,    Pterostilbene and cancer: current review
- Review, Var, NA
TumCCA↑, Apoptosis↑, TumMeta↑, toxicity↓, BioAv↑,
4696- PTS,    BlueBerry Isolate, Pterostilbene, Functions as a Potential Anticancer Stem Cell Agent in Suppressing Irradiation-Mediated Enrichment of Hepatoma Stem Cells
- in-vitro, HCC, NA
CD133↓, CSCs↓,
4695- PTS,    Pterostilbene in Cancer Therapy: Enhancing Treatment Efficacy and Overcoming Resistance
- Review, Var, NA
CSCs↓, ChemoSen↑, BioAv↑, *toxicity↓,
4694- PTS,    Pterostilbene as a Multifaceted Anticancer Agent: Molecular Mechanisms, Therapeutic Potential and Future Directions
BioAv↑, AntiCan↑, Casp↑, TumCCA↑, angioG↓, TumMeta↓, MMP9↓, VEGF↓, CSCs↓, CD44↓, cMyc↓, ChemoSen↑, mTOR↓,
4692- PTS,    Pterostilbene Suppresses both Cancer Cells and Cancer Stem-Like Cells in Cervical Cancer with Superior Bioavailability to Resveratrol
- in-vitro, Cerv, HeLa
TumCG↓, TumMeta↓, TumCCA↑, ROS↑, Apoptosis↑, MMP2↓, MMP9↓, CD133↓, OCT4↓, SOX2↓, Nanog↓, STAT3↓, CSCs↓,
4691- PTS,    Pterostilbene as a Potent Chemopreventive Agent in Cancer
ChemoSen↑, BioAv↑, *Inflam↓, *antiOx↑, AntiCan↑,
4690- PTS,  immuno,    Pterostilbene: Mechanisms of its action as oncostatic agent in cell models and in vivo studies
- Review, Var, NA
eff↑, Half-Life↑, TumCG↓, TumMeta↓, angioG↓, CSCs↓, Apoptosis↑, eff↑, CD44↓, CD24↓,
4689- PTS,    Pterostilbene Suppresses both Cancer Cells and Cancer Stem-Like Cells in Cervical Cancer with Superior Bioavailability to Resveratrol
eff↑, TumCCA↑, ROS↑, MMP2↓, MMP9↓, CSCs↓, CD133↓, OCT4↓, SOX2↓, Nanog↓, STAT3↓, BioAv↑, TumCI↓, ROS↑, Apoptosis↑,
2409- PTS,    Pterostilbene Induces Pyroptosis in Breast Cancer Cells through Pyruvate Kinase 2/Caspase-8/Gasdermin C Signaling Pathway
- in-vitro, BC, EMT6 - in-vitro, BC, 4T1 - in-vitro, Nor, HC11
Pyro↑, Glycolysis↓, *toxicity∅, selectivity↑, GSDMC↑, PKM2↓, PKM1↑, GlucoseCon↓, lactateProd↓, ATP↓, TumCG↓,
2408- PTS,    Pterostilbene suppresses the growth of esophageal squamous cell carcinoma by inhibiting glycolysis and PKM2/STAT3/c-MYC signaling pathway
- in-vitro, ESCC, NA
TumCP↓, TumCMig↓, PKA↓, GlucoseCon↓, lactateProd↓, PKM2↓, STAT3↓, cMyc↓,
2343- QC,    Pharmacological Activity of Quercetin: An Updated Review
- Review, Nor, NA
*ROS↓, *GSH↑, *Catalase↑, *SOD↑, *MDA↓, *GPx↑, *Copper↓, *Iron↓, Apoptosis↓, TumCCA↑, MMP2↓, MMP9↓, GlucoseCon↓, lactateProd↓, PKM2↓, GLUT1↓, LDHA↓, ROS↑,
2300- QC,    Flavonoids Targeting HIF-1: Implications on Cancer Metabolism
- Review, Var, NA
AntiTum↑, Hif1a↓, *Hif1a↑, Glycolysis↓, HK2↓, PDK3↓, PFKP?,
2303- QC,  doxoR,    Quercetin greatly improved therapeutic index of doxorubicin against 4T1 breast cancer by its opposing effects on HIF-1α in tumor and normal cells
- in-vitro, BC, 4T1 - in-vivo, NA, NA
cardioP↑, hepatoP↑, TumCG↓, OS↑, ChemoSen↑, chemoP↑, Hif1a↓, *Hif1a↑, selectivity↑, TumVol↓, OS↑,
2338- QC,    Quercetin: A Flavonoid with Potential for Treating Acute Lung Injury
- Review, Nor, NA
*SIRT1↑, *NLRP3↓, *Inflam↓, *TNF-α↓, *IL1β↓, *IL6↓, *PKM2↓, *HO-1↑, *ROS↓, *NO↓, *MDA↓, *antiOx↑, *COX2↓, *HMGB1↓, *iNOS↓, *NF-kB↓,
2339- QC,    Quercetin protects against LPS-induced lung injury in mice via SIRT1-mediated suppression of PKM2 nuclear accumulation
- in-vivo, Nor, NA
*Inflam↓, *antiOx↑, *NLRP3↓, *Sepsis↓, *PKM2↓, *SIRT1↓,
2340- QC,    Oral Squamous Cell Carcinoma Cells with Acquired Resistance to Erlotinib Are Sensitive to Anti-Cancer Effect of Quercetin via Pyruvate Kinase M2 (PKM2)
- in-vitro, OS, NA
TumCG↓, GlucoseCon↓, TumCI↓, GLUT1↓, PKM2↓, LDHA↓, Glycolysis↓, lactateProd↓, HK2↓, eff↑,
2341- QC,    Quercetin suppresses the mobility of breast cancer by suppressing glycolysis through Akt-mTOR pathway mediated autophagy induction
- in-vitro, BC, MCF-7 - in-vitro, BC, MDA-MB-231 - in-vivo, NA, NA
MMP2↓, MMP9↓, VEGF↓, Glycolysis↓, lactateProd↓, PKM2↓, GLUT1↓, LDHA↓, TumAuto↑, Akt↓, mTOR↓, TumMeta↓, MMP3↓, eff↓, GlucoseCon↓, lactateProd↓, TumAuto↑, LC3B-II↑,
2342- QC,    Quercetin Inhibits the Proliferation of Glycolysis-Addicted HCC Cells by Reducing Hexokinase 2 and Akt-mTOR Pathway
- in-vitro, HCC, Bel-7402 - in-vitro, HCC, SMMC-7721 cell - in-vivo, NA, NA
TumCP↓, HK2↓, Akt↓, mTOR↓, GlucoseCon↓, lactateProd↓, Glycolysis↓,
2431- QC,    The Protective Effect of Quercetin against the Cytotoxicity Induced by Fumonisin B1 in Sertoli Cells
- in-vitro, Nor, TM4
*Apoptosis↓, *ROS↓, *antiOx↓, *MMP↑, *GPI↑, *HK2↑, *ALDOA↑, *PKM1↑, *LDHA↑, *PFKL↑,

Showing Research Papers: 4501 to 4550 of 6108
Prev Page 91 of 123 Next

* indicates research on normal cells as opposed to diseased cells
Total Research Paper Matches: 6108

Pathway results for Effect on Cancer / Diseased Cells:


Redox & Oxidative Stress ⓘ

GSH/GSSG↓, 1,   H2O2↑, 1,   MDA↑, 1,   NRF2↓, 2,   NRF2↑, 1,   ROS?, 1,   ROS↑, 11,   SOD2↓, 1,   SOD2↑, 1,   TrxR↓, 1,  

Mitochondria & Bioenergetics ⓘ

ATP↓, 1,   MEK↑, 1,   MMP↓, 2,  

Core Metabolism/Glycolysis ⓘ

AMPK↓, 1,   p‑AMPK↑, 1,   cMyc↓, 2,   FASN↓, 1,   GlucoseCon↓, 6,   Glycolysis↓, 5,   HK2↓, 3,   lactateProd↓, 7,   LDHA↓, 3,   PDK3↓, 1,   PFKP?, 1,   PKM1↑, 1,   PKM2↓, 5,   p‑S6K↓, 1,   SREBP1↓, 1,  

Cell Death ⓘ

Akt↓, 5,   p‑Akt↓, 1,   Apoptosis↓, 1,   Apoptosis↑, 6,   BAX↑, 4,   Bcl-2↓, 2,   Casp↑, 2,   Casp3↑, 3,   Cyt‑c↑, 1,   Diablo↑, 1,   GSDMC↑, 1,   HGF/c-Met↓, 1,   iNOS↓, 1,   MLKL↑, 1,   Necroptosis↑, 1,   Pyro↑, 1,   RIP1↓, 1,  

Kinase & Signal Transduction ⓘ

p‑TSC2↑, 1,  

Transcription & Epigenetics ⓘ

miR-205↑, 1,   other↓, 1,   tumCV↓, 3,  

Protein Folding & ER Stress ⓘ

CHOP↑, 1,   ER Stress↑, 2,   GRP78/BiP↓, 1,   PERK↑, 1,  

Autophagy & Lysosomes ⓘ

ATG3↑, 1,   ATG5↑, 1,   Beclin-1↑, 1,   LC3B-II↑, 1,   TumAuto↑, 4,  

DNA Damage & Repair ⓘ

p‑P53↑, 1,  

Cell Cycle & Senescence ⓘ

TumCCA?, 1,   TumCCA↑, 8,  

Proliferation, Differentiation & Cell State ⓘ

p‑4E-BP1↓, 1,   CD133↓, 4,   CD24↓, 1,   CD44↓, 3,   CSCs↓, 10,   EMT↓, 4,   ERK↑, 1,   HDAC1↓, 1,   miR-448↑, 1,   mTOR↓, 6,   p‑mTOR↓, 1,   Nanog↓, 2,   NOTCH↓, 1,   OCT4↓, 2,   P70S6K↓, 1,   PI3K↓, 3,   PTEN↑, 4,   SOX2↓, 2,   Src↓, 1,   STAT3↓, 5,   TumCG↓, 10,  

Migration ⓘ

Ca+2↝, 1,   E-cadherin↑, 6,   FAK↓, 1,   Ki-67↓, 1,   miR-19b↓, 1,   MMP2↓, 6,   MMP3↓, 1,   MMP9↓, 7,   MMPs↓, 1,   PKA↓, 1,   RIP3↑, 1,   Slug↓, 1,   Snail↓, 2,   TIMP1↑, 1,   TumCI↓, 6,   TumCMig↓, 5,   TumCP↓, 4,   TumMeta↓, 7,   TumMeta↑, 1,   Twist↓, 3,   Vim↓, 4,   Zeb1↓, 1,   Zeb1↑, 1,   β-catenin/ZEB1↓, 2,  

Angiogenesis & Vasculature ⓘ

angioG↓, 2,   ATF4↑, 1,   Hif1a↓, 2,   VEGF↓, 2,  

Barriers & Transport ⓘ

BBB↑, 3,   GLUT1↓, 3,  

Immune & Inflammatory Signaling ⓘ

COX2↓, 1,   JAK2↓, 1,   NF-kB↓, 6,  

Hormonal & Nuclear Receptors ⓘ

ACTH↓, 1,   GR↓, 1,  

Drug Metabolism & Resistance ⓘ

BioAv↓, 1,   BioAv↑, 7,   ChemoSen↑, 8,   eff↓, 2,   eff↑, 7,   Half-Life↓, 1,   Half-Life↑, 1,   Half-Life↝, 1,   RadioS↑, 1,   selectivity?, 1,   selectivity↑, 2,  

Clinical Biomarkers ⓘ

BP↓, 1,   Ki-67↓, 1,  

Functional Outcomes ⓘ

AntiCan↑, 2,   AntiTum↑, 2,   cardioP↑, 1,   chemoP↑, 1,   hepatoP↑, 1,   OS↑, 2,   toxicity↓, 1,   toxicity↝, 1,   toxicity∅, 1,   TumVol↓, 2,   TumW↓, 1,   Weight∅, 1,  
Total Targets: 142

Pathway results for Effect on Normal Cells:


Redox & Oxidative Stress ⓘ

antiOx↓, 2,   antiOx↑, 6,   Catalase↑, 4,   Copper↓, 1,   GPx↑, 3,   GSH↑, 4,   GSR↑, 2,   H2O2↓, 1,   HNE↓, 1,   HO-1↑, 5,   Iron↓, 1,   lipid-P↓, 3,   MDA↓, 3,   NQO1↑, 2,   NRF2↑, 5,   ROS↓, 11,   ROS↑, 1,   SOD↑, 6,   SOD2↑, 1,  

Mitochondria & Bioenergetics ⓘ

MMP↑, 1,  

Core Metabolism/Glycolysis ⓘ

ALDOA↑, 1,   CREB↑, 1,   p‑CREB↑, 1,   CRM↑, 1,   GPI↑, 1,   HK2↑, 1,   LDHA↑, 1,   LDL↓, 1,   NAD↑, 1,   NADPH↓, 1,   PFKL↑, 1,   PKM1↑, 1,   PKM2↓, 2,   PPARα↑, 2,   SIRT1↓, 1,   SIRT1↑, 1,   SIRT1∅, 1,  

Cell Death ⓘ

Apoptosis↓, 1,   iNOS↓, 3,   JNK↓, 1,   MAPK↓, 1,   MAPK↝, 1,  

DNA Damage & Repair ⓘ

PCNA↓, 1,  

Cell Cycle & Senescence ⓘ

CDK2↓, 1,   CDK4↓, 1,   cycD1/CCND1↓, 1,   cycE/CCNE↓, 1,   RB1↓, 1,  

Proliferation, Differentiation & Cell State ⓘ

ERK↑, 1,   IGF-1↑, 1,  

Migration ⓘ

Cartilage↑, 1,   E-sel↓, 1,   MMP13↓, 1,   MMPs↓, 1,  

Angiogenesis & Vasculature ⓘ

Hif1a↑, 2,   NO↓, 2,  

Barriers & Transport ⓘ

BBB↑, 2,  

Immune & Inflammatory Signaling ⓘ

COX2↓, 3,   HMGB1↓, 1,   IL1β↓, 3,   IL4↓, 1,   IL6↓, 4,   IL8↓, 1,   Inflam↓, 12,   MCP1↓, 1,   Neut↓, 1,   NF-kB↓, 2,   TNF-α↓, 4,  

Synaptic & Neurotransmission ⓘ

BDNF↑, 1,   GABA↑, 1,   PSD95↑, 1,   p‑tau↓, 1,  

Protein Aggregation ⓘ

NLRP3↓, 5,  

Drug Metabolism & Resistance ⓘ

BioAv↑, 6,   Dose↝, 1,   eff↑, 1,   Half-Life↑, 2,  

Clinical Biomarkers ⓘ

BP↓, 1,   GutMicro↑, 3,   IL6↓, 4,  

Functional Outcomes ⓘ

AntiAge↑, 1,   AntiCan↑, 1,   cardioP↑, 2,   cognitive↑, 3,   hepatoP↑, 1,   memory↑, 2,   neuroP↑, 4,   toxicity↓, 3,   toxicity∅, 1,  

Infection & Microbiome ⓘ

Sepsis↓, 1,  
Total Targets: 90

Query results interpretion may depend on "conditions" listed in the research papers.
Such Conditions may include : 
  -low or high Dose
  -format for product, such as nano of lipid formations
  -different cell line effects
  -synergies with other products 
  -if effect was for normal or cancerous cells

Filter Conditions: Pro/AntiFlg:%  IllCat:%  CanType:%  Cells:%  prod#:%  Target#:%  State#:%  Dir#:%
  wNotes=0  sortOrder:rid,rpid

 

Home Page