Cancer Database Query Results

Scientific Papers found: Click to Expand⟱
5281- 3BP,    A translational study “case report” on the small molecule “energy blocker” 3-bromopyruvate (3BP) as a potent anticancer agent: from bench side to bedside
- Case Report, Var, NA
Glycolysis↓, mt-OXPHOS↓, ATP↓, selectivity↑, toxicity↝, OS↑, QoL↑,
5276- 3BP,    A Translational Study 'Case Report' on the Small Molecule 'Energy Blocker' 3-Bromopyruvate (3BP) as a Potent Anticancer Agent: From Bench Side to Bedside(2012)
- Case Report, HCC, NA
Dose↓, Remission↑,
5302- 5-HTP,    Hippocampal ischaemia from accidental 5-Hydroxytryptophan (5-HTP) overdose case report
- Case Report, Nor, NA
*toxicity↑, *Dose↑,
5310- 5-HTP,    5-Hydroxytryptophan toxicity successfully treated by haemodialysis in a dog
- Case Report, Nor, NA
*Dose↑, *toxicity↝,
5301- 5-HTP,    Eosinophilia-myalgia syndrome presenting with overlapping features of eosinophilic fasciitis and sarcoidal granulomas
- Case Report, NA, NA
*toxicity↝, *toxicity↝,
5299- 5-HTP,    Serotonin Syndrome from 5-Hydroxytryptophan Supplement Ingestion in a 9-Month-Old Labrador Retriever
- Case Report, AD, NA
*toxicity↝, *toxicity↝,
5307- 5-HTP,    5-Hydroxytryptophan toxicosis in dogs: 1989-1999
- Case Report, Nor, NA
*toxicity↝, *5HT↑, *Dose↝,
305- AgNPs,    Activity and pharmacology of homemade silver nanoparticles in refractory metastatic head and neck squamous cell cancer
- Case Report, HNSCC, NA
OS↑, Dose↓, BioAv↝, toxicity↓, Remission↑, other↝, other↝, other↝, Dose↝, BioAv↝,
5349- Akk,  immuno,    Improved survival in advanced melanoma patients treated with fecal microbiota transplantation using healthy donor stool in combination with anti-PD1: final results of the MIMic phase 1 trial
- Case Report, Melanoma, NA
eff↑, OS↑, eff↑,
5360- almon,  BEV,    Case report: Almonertinib in combination with bevacizumab for leptomeningeal metastases from epidermal growth factor receptor-mutation non-small cell lung cancer: Case series
- Case Report, NSCLC, NA
BBB↑, Dose↝, eff↓, OS↑,
2502- Bical,    Complete Response of Metastatic Androgen Receptor–Positive Breast Cancer to Bicalutamide: Case Report and Review of the Literature
- Case Report, BC, NA
Dose↝, Remission↑,
5714- Brut,    Probable Interaction of Bergamottin and Cyclosporine in a Lung Transplant Recipient
- Case Report, Nor, NA
*CYP3A4↓,
1582- Citrate,    Clinical report: A patient with primary peritoneal mesothelioma that has improved after taking citric acid orally
- Case Report, PerC, NA
Dose∅, Weight↑, OS↑,
1581- Citrate,    Hypothesis proved. . .citric acid (citrate) does improve cancer:A case of a patient suffering from medullary thyroid cancer
- Case Report, Thyroid, NA
OS↑, Weight↑, Dose∅, eff↑,
1809- CUR,  Oxy,    Long-term stabilisation of myeloma with curcumin
- Case Report, Melanoma, NA
*OS↑, QoL↑, Dose↑, Dose↑, IL6↓, STAT3↓, NF-kB↓, COX2↓,
1877- DCA,    Non-Hodgkin′s Lymphoma Reversal with Dichloroacetate
- Case Report, lymphoma, NA
Remission↑, p‑PDKs↓, Glycolysis↓, i-Ca+2↓, toxicity↓, Dose∅,
1879- DCA,    Long-term stabilization of metastatic melanoma with sodium dichloroacetate
- Case Report, Melanoma, NA
OS↑, toxicity↓, Dose∅, Dose∅, Dose∅, QoL∅,
1880- DCA,    A Novel Form of Dichloroacetate Therapy for Patients With Advanced Cancer: A Report of 3 Cases
- Case Report, Var, NA
OS↑, angioG↓, Hif1a↝, pH↝, QoL↑,
1881- DCA,  Chemo,    Co-treatment of dichloroacetate, omeprazole and tamoxifen exhibited synergistically antiproliferative effect on malignant tumors: in vivo experiments and a case report
- in-vitro, NA, HT1080 - in-vitro, NA, WI38 - Case Report, Var, NA
eff↑, selectivity↑, OS↑,
1868- DCA,  MET,    Long-term stabilization of stage 4 colon cancer using sodium dichloroacetate therapy
- Case Report, NA, NA
eff↑, toxicity∅, MMP↓, Apoptosis↑, selectivity↑, pH↝, Dose↝, Dose↝, eff↑,
2169- dietF,    Prolonged stabilization of platinum-resistant ovarian cancer in a single patient consuming a fermented soy therapy
- Case Report, Ovarian, NA
OS↑, CA125↓, eff↑,
5013- DSF,  Cu,  Z,    Disulfiram inhibits activating transcription factor/cyclic AMP-responsive element binding protein and human melanoma growth in a metal-dependent manner in vitro, in mice and in a patient with metastatic disease
- vitro+vivo, Melanoma, NA - Case Report, Melanoma, NA
P-gp↓, NF-kB↓, ChemoSen↑, angioG↓, TumCG↓, TumMeta↓, Remission↑, toxicity↓, ATF2↓, CREB↓, cycA1/CCNA1↓, TumCG↓, angioG↓, Dose↝, toxicity↝,
638- EGCG,  MushCha,  MushReishi,    A Case of Complete and Durable Molecular Remission of Chronic Lymphocytic Leukemia Following Treatment with Epigallocatechin-3-gallate, an Extract of Green Tea
- Case Report, AML, NA
Remission↑,
652- EGCG,  VitK2,  CUR,    Case Report of Unexpectedly Long Survival of Patient With Chronic Lymphocytic Leukemia: Why Integrative Methods Matter
- Case Report, CLL, NA
Remission↑,
2501- EGCG,    A Case of Complete and Durable Molecular Remission of Chronic Lymphocytic Leukemia Following Treatment with Epigallocatechin-3-gallate, an Extract of Green Tea
- Case Report, AML, NA
OS↑, Remission↑, eff↑, Dose↝,
1636- GAR,    Dangerous dietary supplements: Garcinia cambogia-associated hepatic failure requiring transplantation
- Case Report, Obesity, NA
*Dose∅, *other↑,
789- GE,    Complete remission of pulmonary spindle cell carcinoma after treatment with oral germanium sesquioxide
- Case Report, SCC, NA
Remission↑,
2503- H2,    Brain Metastases Completely Disappear in Non-Small Cell Lung Cancer Using Hydrogen Gas Inhalation: A Case Report
- Case Report, Lung, NA
TumVol↓, OS↑, Dose↝, Dose↝, CEA↓, CA125↓, CYFRA21-1↓, SIRT1↓, COX2↓, IL1β↓, IL6↓, TNF-α↓, HMGB1↓, NF-kB↓, EP2↓,
2530- H2,    Improvement of psoriasis-associated arthritis and skin lesions by treatment with molecular hydrogen: A report of three cases
- Case Report, PSA, NA
eff↑, Dose↝, eff↑, IL6↓, eff↑,
3763- H2,    Long-Term Inhalation of Hydrogen Gas for Patients with Advanced Alzheimer's Disease: A Case Report Showing Improvement in Fecal Incontinence
- Case Report, AD, NA
*cognitive↑, *neuroP↑,
1441- HCQ,  Chemo,    Case report: stage 4 pancreatic cancer to remission using paricalcitol and hydroxychloroquine in addition to traditional chemotherapy
- Case Report, GBM, NA
TumAuto↓, Remission↑,
870- Lae,    Physician Beware: Severe Cyanide Toxicity from Amygdalin Tablets Ingestion
- Case Report, NA, NA
other↑,
3902- MCT,    Effects of Caprylic Triglyceride on Cognitive Performance and Cerebral Glucose Metabolism in Mild Alzheimer’s Disease: A Single-Case Observation
- Case Report, AD, NA
*cognitive↑, *KeyT↑,
3903- MCT,    Retrospective case studies of the efficacy of caprylic triglyceride in mild-to-moderate Alzheimer’s disease
- Case Report, AD, NA
*KeyT↑, *cognitive↑, *eff↑,
5804- MET,  NIV,    Durable Response to Nivolumab Combined With Metformin in Advanced Pancreatic Cancer: A Case Report With Seven Years of Follow-Up.
- Case Report, PC, NA
OS↑, Dose↝,
2490- metroC,    Durable complete response of hepatocellular carcinoma after metronomic capecitabine
- Case Report, HCC, NA
angioG↓, TumVol↓, Remission↑,
2489- metroC,  capec,    Long-lasting response with metronomic capecitabine in advanced hepatocellular carcinoma
- Case Report, HCC, NA
Dose↝, OS↑, TumVol↓, AFP↓,
2486- metroC,  capec,    Sustained complete response of advanced hepatocellular carcinoma with metronomic capecitabine: a report of three cases
- Case Report, HCC, NA
OS↑, eff↝, Dose↝, AFP↓, Dose↝, TumVol↓, AFP↓,
505- MF,    Amplitude-modulated electromagnetic fields for the treatment of cancer: Discovery of tumor-specific frequencies and assessment of a novel therapeutic approach
- Case Report, NA, NA
Pain↓, OS↑,
4569- MFrot,    Case Report: A new noninvasive device-based treatment of a mesencephalic H3 K27M glioma
- Case Report, GBM, NA
Dose↝, Dose↑, Dose↑, OS↑, toxicity↓, ETC↓, ROS↑,
2025- PB,    Complete response of a recurrent, multicentric malignant glioma in a patient treated with phenylbutyrate
- Case Report, GBM, NA
Dose↝, OS↑,
616- VitC,    Suppression of alkaline phosphatase in prostate cancer patients by high dose intravenous Vitamin C Treatment: Three cases
- Case Report, NA, NA
PSA↓, ALP↓,
615- VitC,    High Dose IV Vitamin C and Metastatic Breast Cancer: A Case Report
- Case Report, NA, NA
OS↑, Remission↑,
607- VitC,    Intravenously administered vitamin C as cancer therapy: three cases
- Case Report, NA, NA
necrosis↑, OS↑,
620- VitC,    Case Study: High-Dose Intravenous Vitamin C in the Treatment of a Patient with Adenocarcinoma of the Kidney
- Case Report, NA, NA
OS↑,
2485- VitC,  TACE,    High-Dose Vitamin C Promotes Regression of Multiple Pulmonary Metastases Originating from Hepatocellular Carcinoma
- Case Report, HCC, NA
ROS↑, Dose↝, Dose↝, TumCG↓, Remission↑,
4617- VitD3,    Vitamin D3 and its Potential to Ameliorate Chemical and Radiation-Induced Skin Injury During Cancer Therapy
- Case Report, NA, NA
radioP↑,

Showing Research Papers: 1 to 47 of 47

* indicates research on normal cells as opposed to diseased cells
Total Research Paper Matches: 47

Pathway results for Effect on Cancer / Diseased Cells:


Redox & Oxidative Stress

mt-OXPHOS↓, 1,   ROS↑, 2,  

Mitochondria & Bioenergetics

ATP↓, 1,   ETC↓, 1,   MMP↓, 1,  

Core Metabolism/Glycolysis

CREB↓, 1,   Glycolysis↓, 2,   p‑PDKs↓, 1,   SIRT1↓, 1,  

Cell Death

Apoptosis↑, 1,   ATF2↓, 1,   necrosis↑, 1,  

Transcription & Epigenetics

other↑, 1,   other↝, 3,  

Autophagy & Lysosomes

TumAuto↓, 1,  

Cell Cycle & Senescence

cycA1/CCNA1↓, 1,  

Proliferation, Differentiation & Cell State

EP2↓, 1,   STAT3↓, 1,   TumCG↓, 3,  

Migration

i-Ca+2↓, 1,   CEA↓, 1,   TumMeta↓, 1,  

Angiogenesis & Vasculature

angioG↓, 4,   Hif1a↝, 1,  

Barriers & Transport

BBB↑, 1,   P-gp↓, 1,  

Immune & Inflammatory Signaling

COX2↓, 2,   HMGB1↓, 1,   IL1β↓, 1,   IL6↓, 3,   NF-kB↓, 3,   PSA↓, 1,   TNF-α↓, 1,  

Cellular Microenvironment

pH↝, 2,  

Drug Metabolism & Resistance

BioAv↝, 2,   ChemoSen↑, 1,   Dose↓, 2,   Dose↑, 4,   Dose↝, 18,   Dose∅, 6,   eff↓, 1,   eff↑, 11,   eff↝, 1,   selectivity↑, 3,  

Clinical Biomarkers

AFP↓, 3,   ALP↓, 1,   CA125↓, 2,   CEA↓, 1,   CYFRA21-1↓, 1,   IL6↓, 3,   PSA↓, 1,  

Functional Outcomes

OS↑, 21,   Pain↓, 1,   QoL↑, 3,   QoL∅, 1,   radioP↑, 1,   Remission↑, 13,   toxicity↓, 5,   toxicity↝, 2,   toxicity∅, 1,   TumVol↓, 4,   Weight↑, 2,  
Total Targets: 62

Pathway results for Effect on Normal Cells:


Core Metabolism/Glycolysis

CYP3A4↓, 1,   KeyT↑, 2,  

Transcription & Epigenetics

other↑, 1,  

Synaptic & Neurotransmission

5HT↑, 1,  

Drug Metabolism & Resistance

Dose↑, 2,   Dose↝, 1,   Dose∅, 1,   eff↑, 1,  

Functional Outcomes

cognitive↑, 3,   neuroP↑, 1,   OS↑, 1,   toxicity↑, 1,   toxicity↝, 6,  
Total Targets: 13

Query results interpretion may depend on "conditions" listed in the research papers.
Such Conditions may include : 
  -low or high Dose
  -format for product, such as nano of lipid formations
  -different cell line effects
  -synergies with other products 
  -if effect was for normal or cancerous cells
Filter Conditions: Pro/AntiFlg:%  IllCat:%  CanType:%  Cells:%  prod#:%  Target#:%  State#:%  Dir#:%
wNotes=0 sortOrder:rid,rpid

 

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